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Disease due to contents of killed cancer cells being released into the bloodstream
Tumor lysis syndrome (TLS) is a group of metabolic abnormalities that can occur as a complication from the treatment of cancer, where large amounts of
Tumor_lysis_syndrome
Medication
phosphoribosyltransferase. Allopurinol was also commonly used to treat tumor lysis syndrome in chemotherapeutic treatments, as these regimens can rapidly produce
Allopurinol
Organic compound
oxipurinol. Tumor lysis syndrome, an emergency condition that may result from blood cancers, produces high uric acid levels in blood when tumor cells release
Uric_acid
Treatment of cancer using drugs that inhibit cell division or kill cells
large tumors and cancers with high white cell counts, such as lymphomas, teratomas, and some leukemias, some people develop tumor lysis syndrome. The rapid
Chemotherapy
Low calcium levels in one's blood serum
pancreatitis, calcium channel blocker overdose, rhabdomyolysis, tumor lysis syndrome, and medications such as bisphosphonates or denosumab. Diagnosis
Hypocalcemia
Immunomodulatory drug
include sleepiness, rash, and dizziness. Severe side effects include tumor lysis syndrome, blood clots, and peripheral neuropathy. Thalidomide is a known human
Thalidomide
Human disease
have already formed. Such rapid and massive lysis of tissue poses a risk of complications (tumor lysis syndrome), but it is necessary to avoid a stroke.
Leukostasis
Pharmaceutical drug
(and European counterparts) for the prevention and treatment of tumor lysis syndrome (TLS) in people receiving chemotherapy for hematologic cancers such
Rasburicase
Syndromes
Tsukuhara syndrome Tumor lysis syndrome Tumor necrosis factor receptor associated periodic syndrome Turner syndrome Twiddler's syndrome Twin Anemia-Polycythemia
List_of_syndromes
Topics referred to by the same term
DNA repair Transponder landing system, an airplane landing system Tumor lysis syndrome, a group of metabolic complications that can occur after treatment
TLS
Chemical compound
initiation and ramp-up phase due to potential increased risk of Tumor lysis syndrome. Sonrotoclax was approved for medical use in the United States in
Sonrotoclax
Medical condition
or supplements that contain magnesium. Less common causes include tumor lysis syndrome, seizures, and prolonged ischemia. Diagnosis is based on a blood
Hypermagnesemia
Chemical compound
In phase I trial, 16% of patients receiving the drug developed tumor lysis syndrome. A phase II trial is underway for patients with myeloproliferative
Gandotinib
Excess phosphate in the blood
pseudohypoparathyroidism, hypoparathyroidism, diabetic ketoacidosis, tumor lysis syndrome, and rhabdomyolysis. Diagnosis is generally based on a blood phosphate
Hyperphosphatemia
Medication used in cancer treatment
leukocyte count, low lymphocyte count, interstitial lung disease, tumor lysis syndrome, high uric acid levels, dizziness, blurred vision, atrial fibrillation
Ibrutinib
Medical condition
levels may be decreased. All of these findings together can suggest tumor lysis syndrome. The disease is an uncontrolled proliferation of B cell lymphocytes
Post-transplant lymphoproliferative disorder
Post-transplant_lymphoproliferative_disorder
Excess uric acid in the urine
failure Tumor lysis syndrome Fanconi syndrome Dent's disease (very rare) Acute hyperuricosuria is a common complication of tumor lysis syndrome. This syndrome
Hyperuricosuria
Blood cancer characterized by overproduction of lymphoblasts
the cause is unknown. Genetic risk factors may include Down syndrome, Li–Fraumeni syndrome, or neurofibromatosis type 1. Environmental risk factors may
Acute_lymphoblastic_leukemia
Pair of enantiomers
malignancy, severe cutaneous reactions, hypersensitivity reactions, tumor lysis syndrome, tumor flare reaction, hypothyroidism, and hyperthyroidism. Lenalidomide
Lenalidomide
Subcutaneous fat necrosis of the newborn Traumatic panniculitis Tumor lysis syndrome Weber–Christian disease (relapsing febrile nonsuppurative panniculitis)
List_of_skin_conditions
Italian pharmaceutical company
exposure to uric acid in patients at intermediate to high risk of tumor lysis syndrome: results of the Florence study". 19th Congress of the European Hematology
Menarini
Cancer of the lymphatic system
chemotherapy can be hazardous to the patient, as a phenomenon called "tumor lysis syndrome" could occur. Close monitoring of the patient and adequate hydration
Burkitt_lymphoma
Drugs that modify immune system response
treating IgA-mediated diseases. Cardiac arrest, cytokine release syndrome, tumor lysis syndrome and acute kidney injury, infections, hepatitis B reactivation
Biological_response_modifier
Metabolic medical condition
lymphomas Pheochromocytoma Tumor lysis syndrome D-lactic acidosis due to intestinal bacterial flora production in short gut syndrome Glucose metabolism begins
Lactic_acidosis
Metabolic enzyme expressed in all species except certain primates
lymphoblastic leukemia (B-ALL), often experience tumor lysis syndrome (TLS), which occurs when breakdown of tumor cells by chemotherapy releases uric acid and
Urate_oxidase
Chain reaction of white blood cell activation
in the case of drugs, from other adverse effects; for example, tumor lysis syndrome requires different interventions. As of 2015, differential diagnoses
Cytokine_release_syndrome
White blood cells that have migrated to a tumor
Ivert T, Péterffy A, Nilsonne U, Kreicbergs A, Aparisi T (1986). "Lysis of autologous tumor cells by blood lymphocytes tested at the time of surgery. Correlation
Tumor-infiltrating lymphocytes
Tumor-infiltrating_lymphocytes
Pinching of the intestine between the abdominal aorta and superior mesenteric artery
angle with no symptoms of SMA syndrome. SMA syndrome is also known as Wilkie's syndrome, cast syndrome, mesenteric root syndrome, chronic duodenal ileus and
Superior mesenteric artery syndrome
Superior_mesenteric_artery_syndrome
Excess uric acid in the blood
genetic component), tumor lysis syndrome produces extreme levels of uric acid, mainly leading to kidney failure. The Lesch–Nyhan syndrome is also associated
Hyperuricemia
Season of television series
so he let him loose to avoid media attention. Final diagnosis: Tumor lysis syndrome and steroid-induced psychosis 167 12 "Chase" Matt Shakman Peter Blake
House_season_8
Biopharmaceutical drug
include: Severe infusion reaction Cardiac arrest Cytokine release syndrome Tumor lysis syndrome, causing acute kidney injury Infections Progressive multifocal
Rituximab
Sudden decrease in kidney function that develops within seven days
respectively. Other causes of intrinsic AKI are rhabdomyolysis and tumor lysis syndrome. Certain medication classes such as antibiotics (e.g. amoxicillin/clavulanic
Acute_kidney_injury
Medical condition
under-treated. Infection Deep Vein Thrombosis Pulmonary Embolism Tumor Lysis Syndrome Muscle Aches Symptoms that require immediate treatment include: Fever
Signs_and_symptoms_of_cancer
Medical condition caused by the deposition of calcium salts in the kidneys
typically acute and present only with kidney failure. These include tumor lysis syndrome, acute phosphate nephropathy, and occasional cases of enteric hyperoxaluria
Nephrocalcinosis
TLR tonic labyrinthine reflex TLS tumor lysis syndrome TM tympanic membrane TMA thrombotic microangiopathy TMB tumor mutational burden TME toxic metabolic
List of medical abbreviations: T
List_of_medical_abbreviations:_T
Treatment for non-Hodgkin lymphoma
prophylactically to prevent hyperuricemia that results from tumor lysis syndrome, the result of rapid death of tumor cells.[citation needed] A pivotal study published
CHOP_(chemotherapy)
Medication
thrombocytopenia (low platelet count). Major side effects include tumor lysis syndrome and severe neutropenia. Additionally, this drug may cause fertility
Venetoclax
Medical condition where blood clots block small blood vessels
generates plasmin (in the presence of thrombin), which is responsible for the lysis of fibrin clots. The breakdown of fibrinogen and fibrin results in polypeptides
Disseminated intravascular coagulation
Disseminated_intravascular_coagulation
Medical condition
brittle nail syndrome which manifests as Onychorrhexis and Onychoschizia) Trauma excessive manicuring Trauma which manifests as Onychorrhexis Tumor which manifests
Onycholysis
Excess potassium in the blood
rhabdomyolysis, burns, or any cause of rapid tissue necrosis, including tumor lysis syndrome can cause the release of intracellular potassium into blood, causing
Hyperkalemia
Spectrum of conditions caused by HIV infection
can lead to a spectrum of conditions including acquired immunodeficiency syndrome (AIDS). It is a preventable disease. It can be managed with treatment and
HIV/AIDS
Chemical compound
accelerated approval regulations requiring further clinical studies.) Tumor lysis syndrome (TLS). Clofarabine quickly kills leukaemia cells in the blood. The
Clofarabine
syndrome) Neuropathy, ataxia, and retinitis pigmentosa (NARP syndrome) 277.88 Tumor lysis syndrome 277.89 Other specified disorders of metabolism 278 Obesity
List of ICD-9 codes 240–279: endocrine, nutritional and metabolic diseases, and immunity disorders
List_of_ICD-9_codes_240–279:_endocrine,_nutritional_and_metabolic_diseases,_and_immunity_disorders
Medical procedure involving liver
embolotherapy. It can be thought of as a type of tumor lysis syndrome. After abrupt ischemic tumor cell death, the tumor cells lyse and release their intracellular
Bland_embolization
Natural killer T cells genetically engineered to combat cancer
cytokine release, complementing CAR-mediated lysis. This dual action enhances efficacy against heterogeneous tumors. CAR-NK therapy evolved from CAR-T successes
CAR-NK
Type of cytotoxic lymphocyte
enter, inducing either apoptosis or osmotic cell lysis. The distinction between apoptosis and cell lysis is important in immunology: lysing a virus-infected
Natural_killer_cell
Protein found in humans
fas-mediated lysis in vitro by the Austin Research Institute, Cellular Cytotoxicity Laboratory. More recently, fas-mediated bystander tumor cell killing
Fas_receptor
Metabolic disease involving abnormal deposited amyloid proteins
ATTR amyloidosis, non-cardiac symptoms include: bilateral carpal tunnel syndrome, lumbar spinal stenosis, biceps tendon rupture, small fiber neuropathy
Amyloidosis
Human virus that infects RBC precursors
transcription, assembly of capsids and packaging of the genome, and finally cell lysis with release of the mature virions. In humans the P antigen (also known
Parvovirus_B19
Malignant mesenchymal tumor Malignant mixed Müllerian tumor Malignant paroxysmal ventricular tachycardia Mallory–Weiss syndrome Malonic aciduria Malonyl-CoA
List_of_diseases_(M)
marrow transplant related kidney diseases Radiation nephropathy Tumor lysis syndrome Acute kidney injury in the hospitalized cancer patient. The ethics
Onconephrology
– Marek's disease MeSH C20.683.515.920 – Sézary syndrome MeSH C20.683.515.950 – tumor lysis syndrome MeSH C20.683.780.250 – cryoglobulinemia MeSH C20
List_of_MeSH_codes_(C20)
hypereosinophilic syndrome). Plasmacytomas* are common skin tumors in dogs that derive from B lymphocytes. Most are benign. Tumors of B lymphocyte origin
List_of_dog_diseases
Decreasing kidney function due to high levels of uric acid in the urine
Acute uric acid nephropathy is usually seen as part of the acute tumour lysis syndrome in patients undergoing chemotherapy or radiation therapy for the treatment
Acute_uric_acid_nephropathy
uveoparotid fever MeSH C15.604.515.841 – sezary syndrome MeSH C15.604.515.880 – tumor lysis syndrome MeSH C15.604.515.925 – waldenstrom macroglobulinemia
List_of_MeSH_codes_(C15)
White blood cell with immune function
complex, as has been shown by the ability to cause lysis in non-immunogenic, allogeneic and syngeneic tumors. LAK cells function in the same way as NK cells
Lymphokine-activated killer cell
Lymphokine-activated_killer_cell
Lyon hypothesis Lys Lysate Lysis Lysogen Lysogenic Macromolecule Macrorestriction map Malformation Gene mapping Marfan syndrome Marker gene Mass spectrometry
Index_of_genetics_articles
Type of cytokine produced primarily by monocytes and macrophages
1 and tumor necrosis factor, render cultured vascular endothelial cells susceptible to lysis by antibodies circulating during Kawasaki syndrome". The
Monokine
Medical condition
lymphadenopathy, and/or constitutional symptoms. Unknown fever, cytopenias, tumor lysis syndrome (including lactic acidosis, hyperkalemia, hyperuricemia, hypocalcemia
AIDS-related_lymphoma
Eradicated viral disease
seemed to move from cell to cell, but by around the 12th day, widespread lysis of infected cells occurred and the virus could be found in the bloodstream
Smallpox
Mammalian protein found in humans
production, co-stimulation of CD4+ and CD8+ T cells, and tumor cell susceptibility to T-cell lysis. In addition the CD40/CD40LG axis is important for immune
CD40
Type of white blood cell
ranges from prolonging the neutrophil lifespan to causing rapid neutrophil lysis after phagocytosis. Chlamydia pneumoniae and Neisseria gonorrhoeae have
Neutrophil
Tumor-derived fragmented DNA in the bloodstream
Circulating tumor DNA (ctDNA) is tumor-derived fragmented DNA in the bloodstream that is not associated with cells. ctDNA should not be confused with cell-free
Circulating_tumor_DNA
Informal grouping of viruses
U94 protein is believed to repress genes that are involved in cellular lysis (apoptosis) and also may aid in telomeric integration. Once stored in human
Human_herpesvirus_6
Subtype of white blood cell
spleen and lymph nodes) where they survey for invading pathogens and/or tumor cells. The lymphocytes involved in adaptive immunity (i.e. B and T cells)
Lymphocyte
Lymphoproliferative disorder – Lymphosarcoma – Lymphoscintigraphy – Lynch syndrome – Lysis – Lysosome – Lytic – Lytic lesion M protein – Macroglobulinemia – Macrophage
Index_of_oncology_articles
Genus of viruses
this genus. Diseases associated with this genus can cause histiocytomas, tumor-like masses of mononuclear cells. The genus contains the following species
Yatapoxvirus
Mechanical or functional obstruction of the intestines
hernias, volvulus, endometriosis, inflammatory bowel disease, appendicitis, tumors, diverticulitis, ischemic bowel, tuberculosis and intussusception. Small
Bowel_obstruction
Rare and highly aggressive skin cancer
tumors typically vary in size from 0.5 cm (less than one-quarter of an inch) to more than 5 cm (2 inches) in diameter and may enlarge rapidly. Tumors
Merkel-cell_carcinoma
Species of virus
plates incubate, and then undergo lysis. The plaque that determines whether the phage is present or not is caused by the lysis of the indicator strains. Titers
Bacteriophage_T12
Realm of viruses
capsid. After progeny have been synthesized, lysis occurs. phiX174 and its close relatives use single-gene lysis (Sgl), encoding a single protein that lyses
Volvereviria
Toxin from bacteria that destroys or disrupts cells
Exotoxins may be secreted, or, similar to endotoxins, may be released during lysis of the cell. Gram negative pathogens may secrete outer membrane vesicles
Exotoxin
transposon – Traube cell – trophic level – tropism – tubulin – tumor – turgor – Turner syndrome – twin urea cycle vaccine – vacuole – varicella-zoster virus
Index_of_biology_articles
Genus of viruses (poxes)
brick-shaped intracellular mature virion, which can be released upon cell lysis, or can acquire a second membrane from the Golgi apparatus and bud as extracellular
Orthopoxvirus
Chemical compound
include low blood pressure, tumour lysis syndrome, heart failure, and reversible posterior leukoencephalopathy syndrome. It is in the class of medications
Bortezomib
Inflammation of the mouth, lips, and gums, often due to herpes infection
during this infection include replication of the herpes simplex virus, cell lysis and finally, destruction of the mucosal tissue. HSV-1 can very easily enter
Herpetic_gingivostomatitis
involvement LOA left occipitoanterior (fetal position) level of activity lysis of adhesions Loss of Appetite LOC loss of consciousness level of consciousness
List of medical abbreviations: L
List_of_medical_abbreviations:_L
Medical condition
Stevens–Johnson syndrome (SJS), toxic epidermal necrolysis (TEN), hypersensitivity vasculitis, drug induced hypersensitivity syndrome (DIHS), erythroderma
Drug_eruption
Infectious agent that replicates in cells
the host cell. Release – Viruses can be released from the host cell by lysis, a process that kills the cell by bursting its membrane and cell wall if
Virus
Spasms of the middle ear muscles
Stapedial Tendon Reconstruction for Postoperative Hyperacusis after Tendon Lysis for Middle Ear Myoclonus". Otology & Neurotology: Official Publication of
Middle_ear_myoclonus
agarose gel electrophoresis - agarose gel - akaryocyte - Alagille syndrome - alkaline lysis - allele - amino acids - amino terminus - amp resistance - amplification
Index of molecular biology articles
Index_of_molecular_biology_articles
Species of virus
are assembled for future infection. Mature virions are released via cell lysis and aid in host-to-host transmission of the virus. Extracellular virions
Molluscum_contagiosum_virus
Protein found in humans
recycling, cell adhesion, programmed cell death, and complement-mediated cell lysis. Overexpression of secretory CLU can protect cells from apoptosis induced
Clusterin
Raised body temperature caused by disease
Roth J, Blatteis CM (October 2014). "Mechanisms of fever production and lysis: Lessons from experimental LPS fever". Comprehensive Physiology. 4 (4):
Fever
Chemical compound
galactose/lactose intolerance. Cautions include: Myelosuppression Tumour lysis syndrome Liver impairment History of pancreatitis Check serum lipase periodically
Nilotinib
Process of formation of blood clots
plasminogen activator (t-PA), activate plasminogen into plasmin, which promotes lysis of the fibrin clot; this restores the flow of blood in the damaged/obstructed
Coagulation
Overview of and topical guide to immunology
Tumors History of immunology Timeline of immunology Immunity: Immunity against: Pathogens Pathogenic bacteria Viruses Fungi Protozoa Parasites Tumors
Outline_of_immunology
Drug that inhibits activity of immune system
cyclosporin therapy. Polyclonal antibodies inhibit T lymphocytes and cause their lysis, which is both complement-mediated cytolysis and cell-mediated opsonization
Immunosuppressive_drug
Medical intervention
discectomy Artificial disc replacement or total disc replacement Epidural lysis of adhesions, also known as percutaneous adhesiolysis or the Racz procedure
Minimally invasive spine surgery
Minimally_invasive_spine_surgery
Ulceration of the gastrointestinal tract
disease, and vasculitis. Gastrinomas (Zollinger–Ellison syndrome), or rare gastrin-secreting tumors, also cause multiple and difficult-to-heal ulcers. It
Peptic_ulcer_disease
Family of viruses
protein shells and released from the cell as a result of virally induced cell lysis. Adenovirus is capable of multiplicity reactivation (MR) (Yamamoto and Shimojo
Adenoviridae
S T U V W X Y Z AACTG – acquired immunity – acquired immunodeficiency syndrome (AIDS) – ACT UP/Golden Gate – active immunity – acupuncture – acute HIV
Index of HIV/AIDS-related articles
Index_of_HIV/AIDS-related_articles
Medication
Coagulopathy Red cell aplasia Lymphopenia Anaphylactic reactions Tumour lysis syndrome Rare (<0.1% frequency): Hepatitis B infection or reactivation Ofatumumab
Ofatumumab
Set of chemical reactions in organisms
their efficacy. In various diseases, such as type II diabetes, metabolic syndrome, and cancer, normal metabolism is disrupted. The metabolism of cancer cells
Metabolism
Physical effects resulting from activation of the immune system
pain, redness, swelling, and loss of function (Latin calor, dolor, rubor, tumor, and functio laesa). Inflammation is a generic response, and therefore is
Inflammation
Type of immune cell
inflammation, autoimmune diseases, transplantation reactions, and in anti-tumor immunity. The history of Breg research is can be described as progressing
Regulatory_B_cell
cell lysis. ** CD158F2 Killer cell immunoglobulin-like receptor 2DL5B; encoded by KIR2DL5B gene; inhibits NK cell activity thus prevents cell lysis. **
List of human clusters of differentiation
List_of_human_clusters_of_differentiation
Chemical compound
Pyroptosis is a form of programmed cell death which causes parent cell swelling, Lysis (i.e., the breakdown of their surface membranes), and the release of IL-1β
Itaconic_acid
Medical condition
size with azurophilic granules that contains proteins involved in cell lysis such as perforin and granzyme B. Flow cytometry is also commonly used. Bone
Large granular lymphocytic leukemia
Large_granular_lymphocytic_leukemia
Protein-coding gene in the species Homo sapiens
Moretta A, Biassoni R (1999). "NKp44, A Triggering Receptor Involved in Tumor Cell Lysis by Activated Human Natural Killer Cells, Is a Novel Member of the Immunoglobulin
TYROBP
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TUMOR LYSIS-SYNDROME
TUMOR LYSIS-SYNDROME
TUMOR LYSIS-SYNDROME
TUMOR LYSIS-SYNDROME
TUMOR LYSIS-SYNDROME
TUMOR LYSIS-SYNDROME
TUMOR LYSIS-SYNDROME
TUMOR LYSIS-SYNDROME
TUMOR LYSIS-SYNDROME
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