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CD40

  • CD40
  • Mammalian protein found in humans

    Cluster of differentiation 40, CD40 is a type I transmembrane protein found on antigen-presenting cells and is required for their activation. The binding

    CD40

    CD40

    CD40

  • CD154
  • Protein found in humans

    CD154, also called CD40 ligand or CD40L, is a protein that is primarily expressed on activated T cells and is a member of the TNF superfamily of molecules

    CD154

    CD154

    CD154

  • Hyper IgM syndrome
  • Primary immune deficiency disorders

    recombination (Ig-CSR) deficiencies. The most common causes are mutations in the CD40 Ligand (CD40LG) gene located at Xq26.3-27 leading to X-linked HIGM (XHIGM)

    Hyper IgM syndrome

    Hyper IgM syndrome

    Hyper_IgM_syndrome

  • Antigen-presenting cell
  • Cell that displays antigen bound by MHC proteins on its surface

    several co-stimulatory molecules required for T cell activation, including CD40 and B7. The latter can interact with CD28 on the surface of a CD4+ T cell

    Antigen-presenting cell

    Antigen-presenting cell

    Antigen-presenting_cell

  • Frexalimab
  • Monoclonal antibody

    Frexalimab (SAR441344) is a second-generation monoclonal antibody that inhibits CD40 ligand. It is in development by Sanofi for the treatment of relapsing multiple

    Frexalimab

    Frexalimab

  • B cell
  • Type of white blood cell

    co-stimulatory factor for B cell activation by binding the B cell surface receptor CD40, which promotes B cell proliferation, immunoglobulin class switching, and

    B cell

    B cell

    B_cell

  • Germinal center
  • Lymphatic tissue structure

    interaction between B and T cells in the interfollicular area of the lymph node, CD40-CD40L ligation, NF-kB signaling and expression of IRF4 and BCL6. GC B cells

    Germinal center

    Germinal center

    Germinal_center

  • Act 1 adaptor protein
  • Type of protein

    signaling pathway. Moreover, this protein is only used in cells expressing CD40 and CD40L, which are also from the tumor necrosis receptor superfamily and

    Act 1 adaptor protein

    Act_1_adaptor_protein

  • Macrophage
  • Type of white blood cell

    immunohistochemical staining by their specific expression of proteins such as CD14, CD40, CD11b, CD64, F4/80 (mice)/EMR1 (human), lysozyme M, MAC-1/MAC-3 and CD68

    Macrophage

    Macrophage

    Macrophage

  • Sertoli cell
  • Cells found in human testes which help produce sperm

    T-cells on the periphery. CD40, a molecule associated with dendritic cells (DCs). SCs are able to down regulate the expression of CD40 on the surface of DCs

    Sertoli cell

    Sertoli cell

    Sertoli_cell

  • Helper T cell
  • Type of immune cell

    aid those cells through a combination of cell to cell interactions (e.g. CD40 (protein) and CD40L) and through cytokines.[citation needed] Th cells are

    Helper T cell

    Helper T cell

    Helper_T_cell

  • Seth Lederman
  • American pharmacologist (born 1957)

    Presbyterian Hospital). As assistant professor at Columbia, Lederman discovered the CD40-Ligand (CD154) and elucidated the molecular basis of T cell helper function

    Seth Lederman

    Seth Lederman

    Seth_Lederman

  • Dendritic cell
  • Accessory cell of the mammalian immune system

    co-receptors in T-cell activation such as CD80 (B7.1), CD86 (B7.2), and CD40 greatly enhancing their ability to activate T-cells. They also upregulate

    Dendritic cell

    Dendritic cell

    Dendritic_cell

  • Cytotoxic T cell
  • T cell that kills infected, damaged or cancerous cells

    cells proceeds by signaling between CD154/CD40L on the T helper cell and the CD40 receptor on the antigen-presenting cell during immunological synapse formation

    Cytotoxic T cell

    Cytotoxic T cell

    Cytotoxic_T_cell

  • Lucatumumab
  • Monoclonal antibody

    Lucatumumab (CHIR 12.12 or HCD122) is a human monoclonal antibody against CD40 development of which was discontinued by Novartis in 2013 after it was investigated

    Lucatumumab

    Lucatumumab

  • Dacetuzumab
  • Monoclonal antibody

    is a humanized monoclonal antibody being developed for the treatment of CD40-positive cancers like non-Hodgkin's lymphoma and hematological malignancies

    Dacetuzumab

    Dacetuzumab

  • Tegoprubart
  • Experimental drug

    conference demonstrated that tegoprubart, a monoclonal antibody inhibiting the CD40 ligand, enabled 100% insulin independence in ten evaluable patients following

    Tegoprubart

    Tegoprubart

  • Hypergammaglobulinemia
  • Excess amounts of gamma globulin in the blood

    which codes for CD40 ligand. This gene is located on the long arm of the X chromosome at position 26, denoted Xq26. Normally, CD40 ligand is expressed

    Hypergammaglobulinemia

    Hypergammaglobulinemia

  • Langhans giant cell
  • Cell type

    activated CD4+ T cells and monocytes are in close contact, interaction of CD40-CD40L between these two cells and subsequent IFNγ secretion by the T cells

    Langhans giant cell

    Langhans giant cell

    Langhans_giant_cell

  • Trap
  • Topics referred to by the same term

    receptor-associated proteins TNF-related activation protein, also known as CD40 ligand Tripartite ATP-independent periplasmic transporter, in prokaryotes

    Trap

    Trap

  • Immunotherapy
  • Activation or suppression of the immune system to treat disease

    agonistic antibodies (e.g., anti-CD40) that are conjugated with antigen of interest. Multiple, next-generation anti-CD40 platforms are being actively developed

    Immunotherapy

    Immunotherapy

  • Memory B cell
  • Cell of the adaptive immune system

    T-cell zone will bind to the MHCII ligand. The T cells will then express the CD40 ligand (CD40L) molecule and will begin to secrete cytokines which cause the

    Memory B cell

    Memory B cell

    Memory_B_cell

  • CD37
  • Mammalian protein found in humans

    CD26 CD27 CD28 CD29 CD30 CD31 CD32 A B CD33 CD34 CD35 CD36 CD37 CD38 CD39 CD40 CD41 CD42 a b c d CD43 CD44 CD45 CD46 CD47 CD48 CD49 a b c d e f CD50 51–100

    CD37

    CD37

    CD37

  • Reactive arthritis
  • Inflammatory arthritis triggered by infection elsewhere in the body

    Lanier, L.L. (February 1995). "T-cell costimulation via CD28-CD80/CD86 and CD40-CD40 ligand interactions". Research in Immunology. 146 (3): 171–176. doi:10

    Reactive arthritis

    Reactive arthritis

    Reactive_arthritis

  • AKNA
  • Protein-coding gene in the species Homo sapiens

    different isoforms. AKNA is known to upregulate expression of the receptor CD40 and its ligand CD40L/CD154. AKNA is an essential part in the construction

    AKNA

    AKNA

    AKNA

  • Teneliximab
  • Monoclonal antibody

    a chimeric monoclonal antibody binding to the immune stimulatory protein CD40. As of 2009[update], it has not entered clinical trials. International Nonproprietary

    Teneliximab

    Teneliximab

  • Follicular B helper T cells
  • Type of immune cell involved in germinal center formation and maintenance

    formation and maintenance of germinal centers through the expression of CD40 ligand (CD40L) and the secretion of IL-21 and IL-4. TFH cells also migrate

    Follicular B helper T cells

    Follicular B helper T cells

    Follicular_B_helper_T_cells

  • Esther Lutgens
  • Dutch physician, molecular biologist and professor

    particular, the signalling axis between the protein CD40 and its ligand, CD40L. Lutgens identified that the CD40 ligand was expressed in atherosclerotic plaque

    Esther Lutgens

    Esther_Lutgens

  • Immunoglobulin class switching
  • Biological mechanism

    these activated B cells encounter specific signaling molecules via their CD40 and cytokine receptors (both modulated by T helper cells), they undergo antibody

    Immunoglobulin class switching

    Immunoglobulin class switching

    Immunoglobulin_class_switching

  • List of minor planets: 761001–762000
  • 2010 Mount Lemmon Mount Lemmon Survey EOS 1.5 km MPC · JPL 761582 2010 CD40 — February 13, 2010 Mount Lemmon Mount Lemmon Survey  · 2.2 km MPC · JPL

    List of minor planets: 761001–762000

    List_of_minor_planets:_761001–762000

  • Centroblast
  • Enlarged B cell in the germinal center of lymphoid follicles

    centroblast development. Interaction between CD40 ligand on an activated helper T cell and the B cell CD40 receptor induces centroblasts to express activation-induced

    Centroblast

    Centroblast

    Centroblast

  • Lymphatic system
  • Organ system in vertebrates complementary to the circulatory system

    Olsson Bontell, T; Smits, A; Essand, M; Dimberg, A (5 July 2021). "Agonistic CD40 therapy induces tertiary lymphoid structures but impairs responses to checkpoint

    Lymphatic system

    Lymphatic system

    Lymphatic_system

  • California's 40th congressional district
  • U.S. House district for California

    Election Returns: District Definitions California Voter Foundation map – CD40 33°53′41″N 117°55′23″W / 33.894642°N 117.922955°W / 33.894642; -117.922955

    California's 40th congressional district

    California's_40th_congressional_district

  • Cytokine
  • Category of small signaling proteins

    extracellular binding domain, and includes several other non-cytokine ligands like CD40, CD27 and CD30, besides the ligands on which the family is named. Seven transmembrane

    Cytokine

    Cytokine

    Cytokine

  • Rheumatoid arthritis
  • Type of autoimmune arthritis

    include genes affecting co-stimulatory immune pathways—for example CD28 and CD40, cytokine signaling, lymphocyte receptor activation threshold (e.g., PTPN22)

    Rheumatoid arthritis

    Rheumatoid arthritis

    Rheumatoid_arthritis

  • TTRAP
  • Protein-coding gene in the species Homo sapiens

    and CD40. This gene encodes a member of a superfamily of divalent cation-dependent phosphodiesterases. The encoded protein associates with CD40, tumor

    TTRAP

    TTRAP

  • Immune checkpoint
  • Regulators of the immune system

    are members of the tumor necrosis factor (TNF) receptor superfamily—CD27, CD40, OX40, GITR and CD137. Another two stimulatory checkpoint molecules belong

    Immune checkpoint

    Immune checkpoint

    Immune_checkpoint

  • List of minor planets: 483001–484000
  • 2000 CX39 — January 11, 2000 Socorro LINEAR  · 1.4 km MPC · JPL 483421 2000 CD40 — February 3, 2000 Socorro LINEAR  · 2.1 km MPC · JPL 483422 2000 CE59 —

    List of minor planets: 483001–484000

    List_of_minor_planets:_483001–484000

  • List of minor planets: 580001–581000
  • — October 20, 2003 Kitt Peak Spacewatch  · 3.1 km MPC · JPL 580594 2015 CD40 — November 3, 2004 Kitt Peak Spacewatch GEF 1.5 km MPC · JPL 580595 2015

    List of minor planets: 580001–581000

    List_of_minor_planets:_580001–581000

  • Bhaskar Saha
  • Indian cell biologist (born 1964)

    he is involved in five projects viz. Leishmania-macrophage interaction, CD40 signaling, DC subset mediated priming against prostate cancer, Development

    Bhaskar Saha

    Bhaskar_Saha

  • CAR T cell
  • Genetically engineered T cell

    including the use of nonconventional costimulatory molecules like MyD88/CD40, highlight the innovative approaches being taken to optimize CAR T-cell therapies

    CAR T cell

    CAR_T_cell

  • Toralizumab
  • Monoclonal antibody

    Monoclonal antibody Type Whole antibody Source Humanized (from mouse) Target CD40 ligand Clinical data ATC code none Identifiers CAS Number 252662-47-8 N ChemSpider

    Toralizumab

    Toralizumab

  • List of minor planets: 755001–756000
  • February 2, 2017 Haleakala Pan-STARRS 1  · 1.5 km MPC · JPL 755359 2017 CD40 — February 1, 2017 Mount Lemmon Mount Lemmon Survey  · 1.6 km MPC · JPL 755360

    List of minor planets: 755001–756000

    List_of_minor_planets:_755001–756000

  • CD80
  • Mammalian protein found in humans

    interleukin 2 (IL-2) as well as ɑ-chain of CD25 (which is a receptor of IL-2), CD40 ligand, tumor necrosis factor-α (TNFα), TNF-β, and interferon-γ (IFN-γ).

    CD80

    CD80

    CD80

  • B7 (protein)
  • Integral membrane protein

    to continue the immune response can come from B7-CD28 and CD40–CD40L interactions. When CD40 on the APC binds CD40L(CD154) on the T cell, signals are sent

    B7 (protein)

    B7_(protein)

  • NF-κB
  • Family of transcription factor protein complexes

    Wilson CA, Lee SJ, Zhao X, Benveniste EN (November 2005). "LPS induces CD40 gene expression through the activation of NF-kappaB and STAT-1alpha in macrophages

    NF-κB

    NF-κB

    NF-κB

  • Immune system
  • Biological system protecting an organism against disease

    an upregulation of molecules expressed on the T cell's surface, such as CD40 ligand (also called CD154), which provide extra stimulatory signals typically

    Immune system

    Immune system

    Immune_system

  • Adenoviridae
  • Family of viruses

    (November 2009). "A genetically engineered adenovirus vector targeted to CD40 mediates transduction of canine dendritic cells and promotes antigen-specific

    Adenoviridae

    Adenoviridae

    Adenoviridae

  • B-cell receptor
  • Transmembrane protein on the surface of a B cell

    lymphoid neoplasms. It has been shown that BCR signaling is synchronised with CD40 pathway activation provided by B-T cell interactions, and this seems to be

    B-cell receptor

    B-cell receptor

    B-cell_receptor

  • Hypogammaglobulinemia
  • Human disease

    treatment for many combined primary immunodeficiencies including SCID, CD40 deficiency, CD40 ligand deficiency, and Wiskott-Aldrich syndrome, but has been extended

    Hypogammaglobulinemia

    Hypogammaglobulinemia

  • ALCAM
  • Protein-coding gene in the species Homo sapiens

    CD26 CD27 CD28 CD29 CD30 CD31 CD32 A B CD33 CD34 CD35 CD36 CD37 CD38 CD39 CD40 CD41 CD42 a b c d CD43 CD44 CD45 CD46 CD47 CD48 CD49 a b c d e f CD50 51–100

    ALCAM

    ALCAM

    ALCAM

  • Co-stimulation
  • Signal to activate immune cells

    TNF receptor super-family (TNFRSF) (such as 41-BB, OX40, CD27, GITR, HVEM, CD40, BAFFR, BAFF and others). Additionally, some co-stimulatory molecules belong

    Co-stimulation

    Co-stimulation

  • Melanocyte
  • Melanin-producing cells of the skin

    Importantly, melanocytes stimulated by cytokines express surface proteins such as CD40 and ICAM1 in addition to MHC class II, allowing for co-stimulation of T cells

    Melanocyte

    Melanocyte

    Melanocyte

  • T-cell surface glycoprotein CD3 zeta chain
  • Protein-coding gene in the species Homo sapiens

    CD26 CD27 CD28 CD29 CD30 CD31 CD32 A B CD33 CD34 CD35 CD36 CD37 CD38 CD39 CD40 CD41 CD42 a b c d CD43 CD44 CD45 CD46 CD47 CD48 CD49 a b c d e f CD50 51–100

    T-cell surface glycoprotein CD3 zeta chain

    T-cell surface glycoprotein CD3 zeta chain

    T-cell_surface_glycoprotein_CD3_zeta_chain

  • Gail A. Bishop
  • Immunologist

    Advancement of Science Her publications include: Bishop, Gail A. (2009-10-01). "CD40 and autoimmunity: the dark side of a great activator". Seminars in Immunology

    Gail A. Bishop

    Gail_A._Bishop

  • CD163
  • Protein found in humans

    CD26 CD27 CD28 CD29 CD30 CD31 CD32 A B CD33 CD34 CD35 CD36 CD37 CD38 CD39 CD40 CD41 CD42 a b c d CD43 CD44 CD45 CD46 CD47 CD48 CD49 a b c d e f CD50 51–100

    CD163

    CD163

    CD163

  • LYN
  • Mammalian protein found in Homo sapiens

    surface receptor proteins, including the B cell antigen receptor (BCR), CD40, or CD19. The abbreviation Lyn is derived from Lck/Yes novel tyrosine kinase

    LYN

    LYN

    LYN

  • CD52
  • Protein-coding gene found in humans

    CD26 CD27 CD28 CD29 CD30 CD31 CD32 A B CD33 CD34 CD35 CD36 CD37 CD38 CD39 CD40 CD41 CD42 a b c d CD43 CD44 CD45 CD46 CD47 CD48 CD49 a b c d e f CD50 51–100

    CD52

    CD52

    CD52

  • Integrin alpha 2b
  • Mammalian protein found in Homo sapiens

    CD26 CD27 CD28 CD29 CD30 CD31 CD32 A B CD33 CD34 CD35 CD36 CD37 CD38 CD39 CD40 CD41 CD42 a b c d CD43 CD44 CD45 CD46 CD47 CD48 CD49 a b c d e f CD50 51–100

    Integrin alpha 2b

    Integrin alpha 2b

    Integrin_alpha_2b

  • IL2RA
  • Mammalian protein found in Homo sapiens

    receptor 1-10 TNFR1 (TNFRSF1A) TNFR2 (TNFRSF1B) LTBR (TNFRSF3) CD134 (TNFRSF4) CD40 (TNFRSF5) Fas receptor (TNFRSF6) DcR3 (TNFRSF6B) CD27 (TNFRSF7) CD30 (TNFRSF8)

    IL2RA

    IL2RA

    IL2RA

  • Christina Annunziata
  • American medical oncologist

    and residency training in internal medicine. Her dissertation was titled CD40 signaling Hodgkin's disease. She came to the National Cancer Institute (NCI)

    Christina Annunziata

    Christina Annunziata

    Christina_Annunziata

  • CD79
  • Protein family

    CD26 CD27 CD28 CD29 CD30 CD31 CD32 A B CD33 CD34 CD35 CD36 CD37 CD38 CD39 CD40 CD41 CD42 a b c d CD43 CD44 CD45 CD46 CD47 CD48 CD49 a b c d e f CD50 51–100

    CD79

    CD79

  • Integrin beta 3
  • Mammalian protein found in Homo sapiens

    CD26 CD27 CD28 CD29 CD30 CD31 CD32 A B CD33 CD34 CD35 CD36 CD37 CD38 CD39 CD40 CD41 CD42 a b c d CD43 CD44 CD45 CD46 CD47 CD48 CD49 a b c d e f CD50 51–100

    Integrin beta 3

    Integrin beta 3

    Integrin_beta_3

  • Glycoprotein IX
  • Protein-coding gene in the species Homo sapiens

    CD26 CD27 CD28 CD29 CD30 CD31 CD32 A B CD33 CD34 CD35 CD36 CD37 CD38 CD39 CD40 CD41 CD42 a b c d CD43 CD44 CD45 CD46 CD47 CD48 CD49 a b c d e f CD50 51–100

    Glycoprotein IX

    Glycoprotein IX

    Glycoprotein_IX

  • VPREB1
  • Protein-coding gene in the species Homo sapiens

    CD26 CD27 CD28 CD29 CD30 CD31 CD32 A B CD33 CD34 CD35 CD36 CD37 CD38 CD39 CD40 CD41 CD42 a b c d CD43 CD44 CD45 CD46 CD47 CD48 CD49 a b c d e f CD50 51–100

    VPREB1

    VPREB1

    VPREB1

  • MAPK/ERK pathway
  • Cell signaling pathway

    aberrantly active in Hodgkin disease: a signaling pathway shared by CD30, CD40, and RANK that regulates cell proliferation and survival". Blood. 102 (3):

    MAPK/ERK pathway

    MAPK/ERK_pathway

  • Mannose receptor
  • Protein family

    CD26 CD27 CD28 CD29 CD30 CD31 CD32 A B CD33 CD34 CD35 CD36 CD37 CD38 CD39 CD40 CD41 CD42 a b c d CD43 CD44 CD45 CD46 CD47 CD48 CD49 a b c d e f CD50 51–100

    Mannose receptor

    Mannose_receptor

  • Signal-regulatory protein alpha
  • Protein-coding gene in the species Homo sapiens

    CD26 CD27 CD28 CD29 CD30 CD31 CD32 A B CD33 CD34 CD35 CD36 CD37 CD38 CD39 CD40 CD41 CD42 a b c d CD43 CD44 CD45 CD46 CD47 CD48 CD49 a b c d e f CD50 51–100

    Signal-regulatory protein alpha

    Signal-regulatory protein alpha

    Signal-regulatory_protein_alpha

  • List of therapeutic monoclonal antibodies
  • Bivatuzumab mab humanized CD44 v6 squamous cell carcinoma Bleselumab mab human CD40 organ transplant rejection Blinatumomab Blincyto BiTE mouse CD19 Y pre-B

    List of therapeutic monoclonal antibodies

    List of therapeutic monoclonal antibodies

    List_of_therapeutic_monoclonal_antibodies

  • LILRB3
  • Protein-coding gene in the species Homo sapiens

    CD26 CD27 CD28 CD29 CD30 CD31 CD32 A B CD33 CD34 CD35 CD36 CD37 CD38 CD39 CD40 CD41 CD42 a b c d CD43 CD44 CD45 CD46 CD47 CD48 CD49 a b c d e f CD50 51–100

    LILRB3

    LILRB3

    LILRB3

  • HLA-DMA
  • Protein-coding gene in the species Homo sapiens

    cell activation by interfering with expression of costimulatory molecules CD40 ligand and CD80 (B71)". J. Immunol. 155 (2): 917–24. doi:10.4049/jimmunol

    HLA-DMA

    HLA-DMA

    HLA-DMA

  • Epstein–Barr virus latent membrane protein 1
  • and mediates signaling through the nuclear factor-κB pathway, mimicking CD40 receptor signaling. It is often found in the malignant Reed–Sternberg cells

    Epstein–Barr virus latent membrane protein 1

    Epstein–Barr_virus_latent_membrane_protein_1

  • Kawasaki disease
  • Disease found in young children

    with Asian and non-Asian backgrounds. SNPs in FCGR2A, CASP3, BLK, ITPKC, CD40 and ORAI1 have all been linked to susceptibility, prognosis, and risk of

    Kawasaki disease

    Kawasaki disease

    Kawasaki_disease

  • PDCD1LG2
  • Protein-coding gene in the species Homo sapiens

    CD26 CD27 CD28 CD29 CD30 CD31 CD32 A B CD33 CD34 CD35 CD36 CD37 CD38 CD39 CD40 CD41 CD42 a b c d CD43 CD44 CD45 CD46 CD47 CD48 CD49 a b c d e f CD50 51–100

    PDCD1LG2

    PDCD1LG2

    PDCD1LG2

  • Glycoprotein 130
  • Mammalian protein found in Homo sapiens

    CD26 CD27 CD28 CD29 CD30 CD31 CD32 A B CD33 CD34 CD35 CD36 CD37 CD38 CD39 CD40 CD41 CD42 a b c d CD43 CD44 CD45 CD46 CD47 CD48 CD49 a b c d e f CD50 51–100

    Glycoprotein 130

    Glycoprotein 130

    Glycoprotein_130

  • Immunodeficiency
  • Lack of or compromised immune system

    The key genes associated with immunodeficiency diseases include CD40L, CD40, RAG1, RAG2, IL2RG, and ADA. Here is a summary of some methods utilized to

    Immunodeficiency

    Immunodeficiency

  • Enadenotucirev
  • Species of oncocytic human adenovirus

    contains two transgenes expressing the heavy and light chains for a secreted CD40 agonist monoclonal antibody. NG-641: This vector contains four transgenes

    Enadenotucirev

    Enadenotucirev

  • CD86
  • Mammalian protein found in humans

    Sagurachi group that Treg cells were able to downregulate CD80 and CD86, but not CD40 or MHC class II on DC in a way that was adhesion dependent. Downregulation

    CD86

    CD86

    CD86

  • CD82 (gene)
  • Mammalian protein found in humans

    CD26 CD27 CD28 CD29 CD30 CD31 CD32 A B CD33 CD34 CD35 CD36 CD37 CD38 CD39 CD40 CD41 CD42 a b c d CD43 CD44 CD45 CD46 CD47 CD48 CD49 a b c d e f CD50 51–100

    CD82 (gene)

    CD82 (gene)

    CD82_(gene)

  • IL2RB
  • Protein-coding gene in the species Homo sapiens

    receptor 1-10 TNFR1 (TNFRSF1A) TNFR2 (TNFRSF1B) LTBR (TNFRSF3) CD134 (TNFRSF4) CD40 (TNFRSF5) Fas receptor (TNFRSF6) DcR3 (TNFRSF6B) CD27 (TNFRSF7) CD30 (TNFRSF8)

    IL2RB

    IL2RB

    IL2RB

  • Baculoviral IAP repeat-containing protein 2
  • Protein-coding gene in the species Homo sapiens

    Zoog SJ, Dang TT, Kehry MR, Crute JJ (2001). "Molecular characterization of CD40 signaling intermediates". J. Biol. Chem. 276 (46): 43334–42. doi:10.1074/jbc

    Baculoviral IAP repeat-containing protein 2

    Baculoviral IAP repeat-containing protein 2

    Baculoviral_IAP_repeat-containing_protein_2

  • Decoy receptor 2
  • Protein-coding gene in the species Homo sapiens

    CD26 CD27 CD28 CD29 CD30 CD31 CD32 A B CD33 CD34 CD35 CD36 CD37 CD38 CD39 CD40 CD41 CD42 a b c d CD43 CD44 CD45 CD46 CD47 CD48 CD49 a b c d e f CD50 51–100

    Decoy receptor 2

    Decoy receptor 2

    Decoy_receptor_2

  • IFITM1
  • Protein-coding gene in the species Homo sapiens

    CD26 CD27 CD28 CD29 CD30 CD31 CD32 A B CD33 CD34 CD35 CD36 CD37 CD38 CD39 CD40 CD41 CD42 a b c d CD43 CD44 CD45 CD46 CD47 CD48 CD49 a b c d e f CD50 51–100

    IFITM1

    IFITM1

    IFITM1

  • CD20
  • Mammalian protein found in humans

    physically coupled to major histocompatibility complex class II (MHCII), CD40 and B-cell receptor (BCR). The biological function of CD20 as well as its

    CD20

    CD20

    CD20

  • Dipeptidyl peptidase-4
  • Mammalian protein found in humans

    CD26 CD27 CD28 CD29 CD30 CD31 CD32 A B CD33 CD34 CD35 CD36 CD37 CD38 CD39 CD40 CD41 CD42 a b c d CD43 CD44 CD45 CD46 CD47 CD48 CD49 a b c d e f CD50 51–100

    Dipeptidyl peptidase-4

    Dipeptidyl peptidase-4

    Dipeptidyl_peptidase-4

  • Fucosyltransferase 3
  • Protein and coding gene in humans

    CD26 CD27 CD28 CD29 CD30 CD31 CD32 A B CD33 CD34 CD35 CD36 CD37 CD38 CD39 CD40 CD41 CD42 a b c d CD43 CD44 CD45 CD46 CD47 CD48 CD49 a b c d e f CD50 51–100

    Fucosyltransferase 3

    Fucosyltransferase 3

    Fucosyltransferase_3

  • LILRB2
  • Protein-coding gene in the species Homo sapiens

    CD26 CD27 CD28 CD29 CD30 CD31 CD32 A B CD33 CD34 CD35 CD36 CD37 CD38 CD39 CD40 CD41 CD42 a b c d CD43 CD44 CD45 CD46 CD47 CD48 CD49 a b c d e f CD50 51–100

    LILRB2

    LILRB2

    LILRB2

  • CD48
  • Protein-coding gene in humans

    CD26 CD27 CD28 CD29 CD30 CD31 CD32 A B CD33 CD34 CD35 CD36 CD37 CD38 CD39 CD40 CD41 CD42 a b c d CD43 CD44 CD45 CD46 CD47 CD48 CD49 a b c d e f CD50 51–100

    CD48

    CD48

    CD48

  • Galectin-9
  • Protein-coding gene in the species Homo sapiens

    can also interact with other proteins (CLEC7A, CD137, CD40). For example, an interaction with CD40 on T-cells inhibits their proliferation and induces cell

    Galectin-9

    Galectin-9

    Galectin-9

  • CD1A
  • Protein-coding gene in humans

    CD26 CD27 CD28 CD29 CD30 CD31 CD32 A B CD33 CD34 CD35 CD36 CD37 CD38 CD39 CD40 CD41 CD42 a b c d CD43 CD44 CD45 CD46 CD47 CD48 CD49 a b c d e f CD50 51–100

    CD1A

    CD1A

    CD1A

  • Kinase insert domain receptor
  • Protein-coding gene in the species Homo sapiens

    CD26 CD27 CD28 CD29 CD30 CD31 CD32 A B CD33 CD34 CD35 CD36 CD37 CD38 CD39 CD40 CD41 CD42 a b c d CD43 CD44 CD45 CD46 CD47 CD48 CD49 a b c d e f CD50 51–100

    Kinase insert domain receptor

    Kinase insert domain receptor

    Kinase_insert_domain_receptor

  • TRAF3
  • Protein-coding gene in the species Homo sapiens

    (TNFR) superfamily. This protein participates in the signal transduction of CD40, a TNFR family member important for the activation of the immune response

    TRAF3

    TRAF3

    TRAF3

  • Integrin beta 4
  • Protein-coding gene in the species Homo sapiens

    CD26 CD27 CD28 CD29 CD30 CD31 CD32 A B CD33 CD34 CD35 CD36 CD37 CD38 CD39 CD40 CD41 CD42 a b c d CD43 CD44 CD45 CD46 CD47 CD48 CD49 a b c d e f CD50 51–100

    Integrin beta 4

    Integrin beta 4

    Integrin_beta_4

  • Interleukin-31 receptor
  • Protein in humans

    receptor 1-10 TNFR1 (TNFRSF1A) TNFR2 (TNFRSF1B) LTBR (TNFRSF3) CD134 (TNFRSF4) CD40 (TNFRSF5) Fas receptor (TNFRSF6) DcR3 (TNFRSF6B) CD27 (TNFRSF7) CD30 (TNFRSF8)

    Interleukin-31 receptor

    Interleukin-31_receptor

  • Sjögren's disease
  • Autoimmune disease

    Ohlsson M, Szodoray P, Loro LL, Johannessen AC, Jonsson R (December 2002). "CD40, CD154, Bax and Bcl-2 expression in Sjögren's syndrome salivary glands: a

    Sjögren's disease

    Sjögren's disease

    Sjögren's_disease

  • Waldenström macroglobulinemia
  • Type of blood cancer

    overexpressed. The following signalling pathways have been implicated: CD154/CD40 Akt ubiquitination, p53 activation, and cytochrome c release NF-κB Wnt/beta-catenin

    Waldenström macroglobulinemia

    Waldenström_macroglobulinemia

  • TRAF2
  • Protein-coding gene in humans

    Baculoviral IAP repeat-containing protein 3, CASP8AP2, CD134, CD137, CD27, CD40, CFLAR, CHUK, Caveolin 1, EDARADD, HIVEP3, IKK2, Low affinity nerve growth

    TRAF2

    TRAF2

    TRAF2

  • IL3RA
  • Human gene

    receptor 1-10 TNFR1 (TNFRSF1A) TNFR2 (TNFRSF1B) LTBR (TNFRSF3) CD134 (TNFRSF4) CD40 (TNFRSF5) Fas receptor (TNFRSF6) DcR3 (TNFRSF6B) CD27 (TNFRSF7) CD30 (TNFRSF8)

    IL3RA

    IL3RA

    IL3RA

  • APC Activator
  • Type of immunotherapy

    antigen-specific immune responses. Professional APCs express MHC class II and CD40 molecules as surface receptors, and can be activated through direct interactions

    APC Activator

    APC_Activator

  • Cornelis Melief
  • Dutch immunologist (born 1943)

    Induction of anti-tumor CTL immunity through in vivo triggering of 4-1BB and/or CD40 2007 - Long peptides of 22-45 amino acid residues that induce and/or enhance

    Cornelis Melief

    Cornelis_Melief

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Online names & meanings

  • Shou
  • Boy/Male

    Australian, Chinese, Japanese

    Shou

    Defend; Guard

  • Kavishri
  • Boy/Male

    Indian, Telugu

    Kavishri

    Poet

  • Aneezah
  • Girl/Female

    Arabic, Muslim, Sindhi

    Aneezah

    Female Goat

  • Nasria
  • Girl/Female

    Arabic, British, French

    Nasria

    Good

  • Lidin
  • Boy/Male

    Hindu

    Lidin

  • Jarnail
  • Boy/Male

    Hindu, Indian, Punjabi, Sikh

    Jarnail

    The Commanding Officer

  • Narmin
  • Boy/Male

    Arabic, Muslim

    Narmin

    Sensitive; Soft; Clean

  • Bashair
  • Girl/Female

    Indian

    Bashair

    Another name of holy Quran, Good news, Good omens

  • Ahzab
  • Boy/Male

    Indian

    Ahzab

    A narrator of Hadith

  • Rawahah
  • Boy/Male

    Muslim/Islamic

    Rawahah

    Departure Fragrance, ease

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Other words and meanings similar to

CD40

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CD40