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INTEGRIN ALPHA-2

  • Integrin alpha 2
  • Mammalian protein found in Homo sapiens

    Integrin alpha-2, or CD49b (cluster of differentiation 49b), is a protein which in humans is encoded by the CD49b gene. The CD49b protein is an integrin

    Integrin alpha 2

    Integrin alpha 2

    Integrin_alpha_2

  • Integrin alpha 3
  • Mammalian protein found in Homo sapiens

    Integrin alpha-3 is a protein that in humans is encoded by the ITGA3 gene. ITGA3 is an integrin alpha subunit. Together with beta-1 subunit, it makes

    Integrin alpha 3

    Integrin alpha 3

    Integrin_alpha_3

  • Integrin beta 1
  • Mammalian protein found in Homo sapiens

    with integrin alpha 1 and integrin alpha 2 to form integrin complexes which function as collagen receptors. It also forms dimers with integrin alpha 3 to

    Integrin beta 1

    Integrin beta 1

    Integrin_beta_1

  • Integrin alpha X
  • Mammalian protein found in Homo sapiens

    known as Integrin, alpha X (complement component 3 receptor 4 subunit) (ITGAX), is a gene that encodes for CD11c . CD11c is an integrin alpha X chain protein

    Integrin alpha X

    Integrin alpha X

    Integrin_alpha_X

  • Integrin alpha V
  • Mammalian protein found in Homo sapiens

    Integrin alpha-V is a protein that in humans is encoded by the ITGAV gene. ITGAV encodes integrin alpha chain V. Integrins are heterodimeric integral membrane

    Integrin alpha V

    Integrin alpha V

    Integrin_alpha_V

  • Integrin alpha 4
  • Mammalian protein found in Homo sapiens

    is an integrin alpha subunit. It makes up half of the α4β1 lymphocyte homing receptor. The product of this gene belongs to the integrin alpha chain family

    Integrin alpha 4

    Integrin alpha 4

    Integrin_alpha_4

  • Integrin alpha 5
  • Protein

    Integrin alpha-5 is a protein that in humans is encoded by the ITGA5 gene. The product of this gene belongs to the integrin alpha chain family. Integrins

    Integrin alpha 5

    Integrin alpha 5

    Integrin_alpha_5

  • Integrin alpha 7
  • Alpha-7 integrin is a protein that in humans is encoded by the ITGA7 gene. Alpha-7 integrin is critical for modulating cell-matrix interactions. Alpha-7

    Integrin alpha 7

    Integrin alpha 7

    Integrin_alpha_7

  • Integrin alpha 6
  • Mammalian protein found in Homo sapiens

    Integrin alpha-6 is a protein that in humans is encoded by the ITGA6 gene. The ITGA6 protein product is the integrin alpha chain alpha 6. Integrins are

    Integrin alpha 6

    Integrin alpha 6

    Integrin_alpha_6

  • Integrin alpha-1
  • Mammalian protein found in Homo sapiens

    Integrin alpha-1 also CD49a is an integrin alpha subunit encoded in humans by the gene ITGA1. It makes up half of the α1β1 integrin duplex. Though CD49a

    Integrin alpha-1

    Integrin alpha-1

    Integrin_alpha-1

  • Integrin alpha L
  • Mammalian protein found in Homo sapiens

    Integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide), also known as ITGAL, is a protein that in humans

    Integrin alpha L

    Integrin alpha L

    Integrin_alpha_L

  • Integrin alpha 9
  • Protein-coding gene in the species Homo sapiens

    Integrin alpha-9 is a protein that in humans is encoded by the ITGA9 gene. Cytogenetic location: 3p22.2 This gene encodes an alpha integrin. Integrins

    Integrin alpha 9

    Integrin alpha 9

    Integrin_alpha_9

  • Integrin alpha 2b
  • Mammalian protein found in Homo sapiens

    Integrin alpha-IIb is a protein that in humans is encoded by the ITGA2B gene. ITGA2B, also known as CD41, encodes integrin alpha chain 2b. Integrins are

    Integrin alpha 2b

    Integrin alpha 2b

    Integrin_alpha_2b

  • Integrin
  • Transmembrane receptors involved in cellular adhesion and signalling

    Integrins are transmembrane receptors that help cell–cell and cell–extracellular matrix (ECM) adhesion. Upon ligand binding, integrins activate signal

    Integrin

    Integrin

    Integrin

  • Integrin alpha M
  • Mammalian protein found in Homo sapiens

    Integrin alpha M (ITGAM) is one protein subunit that forms heterodimeric integrin alpha-M beta-2 (αMβ2) molecule, also known as macrophage-1 antigen (Mac-1)

    Integrin alpha M

    Integrin alpha M

    Integrin_alpha_M

  • Integrin alpha 11
  • Protein-coding gene in the species Homo sapiens

    Integrin alpha-11 is a protein that, in humans, is encoded by the ITGA11 gene. This gene encodes an alpha integrin. Integrins are heterodimeric integral

    Integrin alpha 11

    Integrin alpha 11

    Integrin_alpha_11

  • Integrin beta 2
  • Mammalian protein found in Homo sapiens

    CD18 (Integrin beta chain-2) is an integrin beta chain protein that is encoded by the ITGB2 gene in humans. Upon binding with one of a number of alpha chains

    Integrin beta 2

    Integrin beta 2

    Integrin_beta_2

  • Integrin alpha D
  • Protein-coding gene in the species Homo sapiens

    Integrin alpha-D is a protein that in humans is encoded by the ITGAD gene. GRCh38: Ensembl release 89: ENSG00000156886 – Ensembl, May 2017 GRCm38: Ensembl

    Integrin alpha D

    Integrin alpha D

    Integrin_alpha_D

  • Integrin alpha 8
  • Protein-coding gene in the species Homo sapiens

    Integrin alpha-8 is a protein that in humans is encoded by the ITGA8 gene. GRCh38: Ensembl release 89: ENSG00000077943 – Ensembl, May 2017 GRCm38: Ensembl

    Integrin alpha 8

    Integrin alpha 8

    Integrin_alpha_8

  • VLA-4
  • Integrin dimer

    Integrin α4β1 (very late antigen-4) is an integrin dimer. It is composed of CD49d (alpha 4) and CD29 (beta 1). The alpha 4 subunit is 155 kDa, and the

    VLA-4

    VLA-4

    VLA-4

  • Integrin alpha E
  • Protein-coding gene in the species Homo sapiens

    Integrin, alpha E (ITGAE) also known as CD103 (cluster of differentiation 103) is an integrin protein that in human is encoded by the ITGAE gene. CD103

    Integrin alpha E

    Integrin alpha E

    Integrin_alpha_E

  • Integrin beta 6
  • Protein-coding gene in the species Homo sapiens

    Integrin beta-6 is a protein that in humans is encoded by the ITGB6 gene. It is the β6 subunit of the integrin αvβ6. Integrins are αβ heterodimeric glycoproteins

    Integrin beta 6

    Integrin beta 6

    Integrin_beta_6

  • LPAM-1
  • Protein complex

    Integrin α4β7 (Lymphocyte Peyer’s patch adhesion molecule-1) is an integrin heterodimer composed of CD49d (alpha-4) subunit and beta-7 subunit noncovalently

    LPAM-1

    LPAM-1

  • Integrin beta 3
  • Mammalian protein found in Homo sapiens

    ITGB3 protein product is the integrin beta chain beta 3. Integrins are integral cell-surface proteins composed of an alpha chain and a beta chain. A given

    Integrin beta 3

    Integrin beta 3

    Integrin_beta_3

  • Integrin beta 7
  • Integrin beta-7 is an integrin protein that in humans is encoded by the ITGB7 gene. It can pair with ITGA4 (CD49d) to form the heterodimeric integrin

    Integrin beta 7

    Integrin beta 7

    Integrin_beta_7

  • Integrin alpha 10
  • Protein-coding gene in the species Homo sapiens

    Integrin alpha-10 also known as ITGA10 is a protein that in humans is encoded by the ITGA10 gene. Integrins are integral membrane proteins composed of

    Integrin alpha 10

    Integrin alpha 10

    Integrin_alpha_10

  • Integrin beta 5
  • Protein-coding gene in the species Homo sapiens

    subunit of integrin that can interact with the integrin alpha v to form the integrin alpha v beta 5 integrin heterodimer. Integrin alpha V beta 5 is

    Integrin beta 5

    Integrin beta 5

    Integrin_beta_5

  • Vatelizumab
  • Pharmaceutical compound

    Vatelizumab is an immunomodulator. It binds to integrin alpha 2. It was withdrawn from Phase II trials for inflammatory bowel disease due to a lack of

    Vatelizumab

    Vatelizumab

  • Glycoprotein IIb/IIIa
  • Integrin complex found on platelets

    medicine, glycoprotein IIb/IIIa (GPIIb/IIIa, also known as integrin αIIbβ3) is an integrin complex found on platelets. It is a transmembrane receptor

    Glycoprotein IIb/IIIa

    Glycoprotein_IIb/IIIa

  • Integrin beta 4
  • Protein-coding gene in the species Homo sapiens

    Integrin, beta 4 (ITGB4) also known as CD104 (Cluster of Differentiation 104), is a human gene. Integrins are heterodimers composed of alpha and beta subunits

    Integrin beta 4

    Integrin beta 4

    Integrin_beta_4

  • Vedolizumab
  • Medication used for the treatment of gastro-intestinal diseases

    to integrin α4β7 (LPAM-1, lymphocyte Peyer's patch adhesion molecule 1, a dimer of Integrin alpha-4 and Integrin beta-7), blocking the α4β7 integrin results

    Vedolizumab

    Vedolizumab

  • Integrin beta 8
  • Protein-coding gene in the species Homo sapiens

    This protein noncovalently binds to an alpha subunit to form a heterodimeric integrin complex. In general, integrin complexes mediate cell-cell and cell-extracellular

    Integrin beta 8

    Integrin beta 8

    Integrin_beta_8

  • Collagen, type XVII, alpha 1
  • Mammalian protein found in humans

    ectodomain, within amino acids 506-519, is responsible for binding to alpha 6 integrin, this binding seems to be important for the collagen XVII integration

    Collagen, type XVII, alpha 1

    Collagen, type XVII, alpha 1

    Collagen,_type_XVII,_alpha_1

  • Alpha-actinin-3
  • Mammalian protein found in Homo sapiens

    neutrophils induces an interaction between the integrin beta 2-subunit (CD18) and the actin binding protein alpha-actinin". Journal of Immunology. 151 (7).

    Alpha-actinin-3

    Alpha-actinin-3

    Alpha-actinin-3

  • Macrophage-1 antigen
  • antigen (or integrin αMβ2 or macrophage integrin or Mac-1) is a complement receptor ("CR3") consisting of CD11b (integrin αM) and CD18 (integrin β2). The

    Macrophage-1 antigen

    Macrophage-1_antigen

  • Alpha-actinin-2
  • Protein-coding gene in the species Homo sapiens

    Alpha-actinin-2 is a protein which in humans is encoded by the ACTN2 gene. This gene encodes an alpha-actinin isoform that is expressed in both skeletal

    Alpha-actinin-2

    Alpha-actinin-2

    Alpha-actinin-2

  • Cell adhesion molecule
  • Subset of cell adhesion proteins

    survival, and transcription. Integrins are heterodimeric, as they consist of an alpha and beta subunit. There are currently 18 alpha subunits and 8 beta subunits

    Cell adhesion molecule

    Cell_adhesion_molecule

  • Natalizumab
  • Medication used to treat multiple sclerosis and Crohn's disease

    a humanized monoclonal antibody against the cell adhesion molecule α4-integrin. It is given by intravenous infusion. The drug is believed to work by reducing

    Natalizumab

    Natalizumab

    Natalizumab

  • Collagen, type III, alpha 1
  • Mammalian protein

    (monomers), each called an alpha 1 chain of type III collagen. Formally, the monomers are called collagen type III, alpha-1 chain and in humans are encoded

    Collagen, type III, alpha 1

    Collagen, type III, alpha 1

    Collagen,_type_III,_alpha_1

  • Lymphocyte function-associated antigen 1
  • Integrin found on lymphocytes

    Lymphocyte function-associated antigen 1 (LFA-1) is an integrin found on lymphocytes and other leukocytes. LFA-1 plays a key role in emigration, which

    Lymphocyte function-associated antigen 1

    Lymphocyte_function-associated_antigen_1

  • Lymph node stromal cell
  • migration. Alpha-7 integrin pericytes (AIPs) express several types of integrin chains which generate heterodimers. Integrin chains allow integrin pericytes

    Lymph node stromal cell

    Lymph_node_stromal_cell

  • Vitaxin
  • Pharmaceutical compound

    (MEDI-523) is a humanized monoclonal antibody against the vascular integrin alpha-v beta-3. It is shown to be a promising angiogenesis inhibitor used

    Vitaxin

    Vitaxin

  • Adhesion molecule (immunoglobulin-like)
  • Protein domain

    of immunoglobulin superfamily domains 1 and 2 of MAdCAM-1 reveals novel features important for integrin recognition". Structure. 6 (6): 793–801. doi:10

    Adhesion molecule (immunoglobulin-like)

    Adhesion molecule (immunoglobulin-like)

    Adhesion_molecule_(immunoglobulin-like)

  • Von Willebrand factor
  • Mammalian protein involved in blood clotting

    I and III. The C4 domain: Contains an RGD motif that binds to platelet integrin αIIbβ3. The CK (cystine knot) domain at the protein's C-terminal end: Involved

    Von Willebrand factor

    Von Willebrand factor

    Von_Willebrand_factor

  • Fibroblast activation protein, alpha
  • Enzyme in humans

    Fibroblast activation protein alpha (FAP-alpha) also known as prolyl endopeptidase FAP is an enzyme that in humans is encoded by the FAP gene. Prolyl endopeptidase

    Fibroblast activation protein, alpha

    Fibroblast activation protein, alpha

    Fibroblast_activation_protein,_alpha

  • Timothy A. Springer
  • American immunologist

    ; Weissman, I. L.; Hamann, A.; Butcher, E. C. (16 July 1993). "Alpha 4 beta 7 integrin mediates lymphocyte binding to the mucosal vascular addressin MAdCAM-1"

    Timothy A. Springer

    Timothy_A._Springer

  • Integrin-linked kinase
  • Protein found in humans

    Integrin-linked kinase is an enzyme that in humans is encoded by the ILK gene involved with integrin-mediated signal transduction. Mutations in ILK are

    Integrin-linked kinase

    Integrin-linked kinase

    Integrin-linked_kinase

  • LAMA2 related congenital muscular dystrophy
  • Medical condition neuromuscular disorders

    namely integrin-α7β1 and α-dystroglycan. In LAMA2-CMD the laminin alpha2 deficiency results in malfunctioning or down regulation of integrin-α7β1 and

    LAMA2 related congenital muscular dystrophy

    LAMA2 related congenital muscular dystrophy

    LAMA2_related_congenital_muscular_dystrophy

  • Transforming growth factor beta
  • Cytokine

    Kawakatsu H, Griffiths MJ, Dalton SL, Wu J, et al. (February 1999). "The integrin alpha v beta 6 binds and activates latent TGF beta 1: a mechanism for regulating

    Transforming growth factor beta

    Transforming growth factor beta

    Transforming_growth_factor_beta

  • Alpha chain
  • Subunit of a protein

    receptor, the fibrinogen alpha chain, the integrin alpha chain, Hemoglobin, alpha 1 It should be distinguished from the term alpha helix, which refers to

    Alpha chain

    Alpha_chain

  • List of human clusters of differentiation
  • not listed on hcdm Bennett JS. Structure and function of the platelet integrin alphaIIbbeta3. J Clin Invest 2005; 115:3363-9. "FITC Anti-human CD51 Antibody

    List of human clusters of differentiation

    List_of_human_clusters_of_differentiation

  • CD9
  • Human protein-encoding gene

    Robertson C, McNicol A (January 2001). "CD63 associates with the alphaIIb beta3 integrin-CD9 complex on the surface of activated platelets". Thrombosis

    CD9

    CD9

    CD9

  • Periostin
  • Protein-coding gene in the species Homo sapiens

    OSF-2) is a protein that in humans is encoded by the POSTN gene. Periostin functions as a ligand for alpha-V/beta-3 and alpha-V/beta-5 integrins to support

    Periostin

    Periostin

    Periostin

  • Arginylglycylaspartic acid
  • Chemical compound

    known as iRGD, is a cyclic peptide that homes to tumors via binding to integrin alpha V receptors. It also binds and activates neuropilin-1, leading to a

    Arginylglycylaspartic acid

    Arginylglycylaspartic acid

    Arginylglycylaspartic_acid

  • ICAM-1
  • Mammalian protein found in Homo sapiens

    expressed on endothelial cells and cells of the immune system. It binds to integrins of type CD11a / CD18, or CD11b / CD18 and is also exploited by rhinovirus

    ICAM-1

    ICAM-1

    ICAM-1

  • Ga-68-Trivehexin
  • Contrast agent for cancer imaging

    targets (i.e., binds to) the cell surface receptor αvβ6-integrin and accumulates in αvβ6-integrin-abundant tissues after intravenous (i.v.) application

    Ga-68-Trivehexin

    Ga-68-Trivehexin

    Ga-68-Trivehexin

  • Collagen, type XVI, alpha 1
  • Protein found in humans

    Collagen alpha-1(XVI) chain is a protein that in humans is encoded by the COL16A1 gene. This gene encodes the alpha chain of type XVI collagen, a member

    Collagen, type XVI, alpha 1

    Collagen, type XVI, alpha 1

    Collagen,_type_XVI,_alpha_1

  • FERMT3
  • Protein-coding gene in the species Homo sapiens

    altering the molecule's conformation. Modification of integrin's conformation serves to dissociate alpha and beta subunits by disrupting their interactions

    FERMT3

    FERMT3

    FERMT3

  • Laminin, alpha 5
  • Protein-coding gene in the species Homo sapiens

    2000). "Integrin binding specificity of laminin-10/11: laminin-10/11 are recognized by alpha 3 beta 1, alpha 6 beta 1 and alpha 6 beta 4 integrins". Journal

    Laminin, alpha 5

    Laminin, alpha 5

    Laminin,_alpha_5

  • Leukocyte extravasation
  • Movement of white blood cells out of blood vessels and towards the inflamed site

    juxtacrine activation of integrins by chemokines and soluble factors released by endothelial cells. In the activated state, integrins bind tightly to complementary

    Leukocyte extravasation

    Leukocyte extravasation

    Leukocyte_extravasation

  • Fibronectin
  • Protein involved in cell adhesion, cell growth, cell migration and differentiation

    extracellular matrix that binds to membrane-spanning receptor proteins called integrins. Fibronectin also binds to other extracellular matrix proteins such as

    Fibronectin

    Fibronectin

    Fibronectin

  • Focal adhesion
  • Structures which transmit force and signals between a cell and the extracellular matrix

    DGEA and GFOGER motifs found in collagen. Integrins are heterodimers which are formed from one beta and one alpha subunit. These subunits are present in

    Focal adhesion

    Focal adhesion

    Focal_adhesion

  • Platelet membrane glycoprotein
  • Surface glycoproteins involved in hemostasis

    (link) Calvete JJ (1995). "On the structure and function of platelet integrin alpha IIb beta 3, the fibrinogen receptor". Proc. Soc. Exp. Biol. Med. 208

    Platelet membrane glycoprotein

    Platelet_membrane_glycoprotein

  • Laminin
  • Protein in the extracellular matrix

    includes the brain and muscle fibers. In muscle, it binds to alpha-dystroglycan and integrin alpha7—beta1 via the G domain, and via the other end, it binds

    Laminin

    Laminin

    Laminin

  • Tenascin C
  • Human protein-coding gene

    attachment and spreading on human tenascin is mediated by alpha 2 beta 1 and alpha v beta 3 integrins". Journal of Cell Science. 105 (4): 1001–1012. doi:10

    Tenascin C

    Tenascin C

    Tenascin_C

  • Biological therapy for inflammatory bowel disease
  • Medical treatment

    proinflammatory cytokines. The alpha 4 integrin on inflammatory cells interacts with these adhesion molecules to allow for migration. Integrin receptor antagonists

    Biological therapy for inflammatory bowel disease

    Biological therapy for inflammatory bowel disease

    Biological_therapy_for_inflammatory_bowel_disease

  • Talin (protein)
  • Protein domain

    codistributes with concentrations of integrins in the plasma membrane. Furthermore, in vitro binding studies suggest that integrins bind to talin, although with

    Talin (protein)

    Talin_(protein)

  • Collagen, type XXIII, alpha 1
  • Mammalian protein found in humans

    β1 integrins. Collagen XXIII interacts in an ion-and conformation-dependent manner with integrin α2β1. Integrin α2β1 is a collagen-binding integrin present

    Collagen, type XXIII, alpha 1

    Collagen, type XXIII, alpha 1

    Collagen,_type_XXIII,_alpha_1

  • Alveolar macrophage
  • Macrophage found in the lungs

    thus inducing the expression of the αvβ6 integrin. Integrins are dimeric cell-surface receptors composed of alpha and beta subunits, which activates TGF-β

    Alveolar macrophage

    Alveolar macrophage

    Alveolar_macrophage

  • Von Willebrand factor type A domain
  • Protein Domain

    "Crystal structure of the I-domain from the CD11a/CD18 (LFA-1, alpha L beta 2) integrin". Proc. Natl. Acad. Sci. U.S.A. 92 (22): 10277–81. Bibcode:1995PNAS

    Von Willebrand factor type A domain

    Von Willebrand factor type A domain

    Von_Willebrand_factor_type_A_domain

  • Platelet plug
  • Aggregation of platelets formed during early stage of coagulation

    adhesion. This process will then be mediated by integrins, such as β1 (α2β1, α5β1) and β3 (αIIbβ3) integrins. In addition, platelets are activated, they will

    Platelet plug

    Platelet_plug

  • Collagen, type V, alpha 1
  • Protein found in humans

    "Mac-2 binding protein is a cell-adhesive protein of the extracellular matrix which self-assembles into ring-like structures and binds beta1 integrins, collagens

    Collagen, type V, alpha 1

    Collagen, type V, alpha 1

    Collagen,_type_V,_alpha_1

  • Addressin
  • Protein found in humans

    (MAdCAM-1) demonstrates structural and functional similarities to the alpha 4 beta 7-integrin binding domains of murine MAdCAM-1, but extreme divergence of mucin-like

    Addressin

    Addressin

    Addressin

  • Alpha-1B adrenergic receptor
  • Protein-coding gene in the species Homo sapiens

    function of Gh/transglutaminase 2 inhibits cell migration through interaction with cytoplasmic tail of integrin alpha subunits". J. Biol. Chem. 279 (35):

    Alpha-1B adrenergic receptor

    Alpha-1B adrenergic receptor

    Alpha-1B_adrenergic_receptor

  • Bone sialoprotein
  • Protein-coding gene in the species Homo sapiens

    human variant of BSP is called bone sialoprotein 2 also known as cell-binding sialoprotein or integrin-binding sialoprotein and is encoded by the IBSP

    Bone sialoprotein

    Bone sialoprotein

    Bone_sialoprotein

  • Leukocyte adhesion deficiency
  • Medical condition

    chromosome 21. This subunit is involved in the formation of the β-2 integrins (LFA-1, integrin alphaXbeta2/CR4/p150,95, and Mac-1/CR3) by dimerization with different

    Leukocyte adhesion deficiency

    Leukocyte_adhesion_deficiency

  • Alpha-actinin-1
  • Protein-coding gene in the species Homo sapiens

    Alpha-actinin-1 is a protein that in humans is encoded by the ACTN1 gene. Alpha actinins belong to the spectrin gene superfamily which represents a diverse

    Alpha-actinin-1

    Alpha-actinin-1

    Alpha-actinin-1

  • PKC alpha
  • Protein-coding gene in the species Homo sapiens

    Protein kinase C alpha (PKCα) is an enzyme that in humans is encoded by the PRKCA gene. Protein kinase C (PKC) is a family of serine- and threonine-specific

    PKC alpha

    PKC alpha

    PKC_alpha

  • TGF beta Activation
  • J. F.; Kaminski, N.; Garat, C.; Matthay, M. A.; et al. (1999). "The integrin alpha v beta 6 binds and activates latent TGF beta 1: a mechanism for regulating

    TGF beta Activation

    TGF_beta_Activation

  • Laminin, alpha 3
  • Protein-coding gene in the species Homo sapiens

    α3β1 Integrin, and Mitogen-activated Protein Kinase Can Regulate Epithelial Cell Proliferation". Mol. Biol. Cell. 10 (2): 259–70. doi:10.1091/mbc.10.2.259

    Laminin, alpha 3

    Laminin, alpha 3

    Laminin,_alpha_3

  • Collagen, type VI, alpha 3
  • Mammalian protein found in humans

    Collagen alpha-3(VI) chain is a protein that in humans is encoded by the COL6A3 gene. This protein is an alpha chain of type VI collagen that aids in

    Collagen, type VI, alpha 3

    Collagen, type VI, alpha 3

    Collagen,_type_VI,_alpha_3

  • VCAM-1
  • Protein-coding gene in the species Homo sapiens

    Yonekawa K, Harlan JM (2005). "Targeting leukocyte integrins in human diseases". J. Leukoc. Biol. 77 (2): 129–40. doi:10.1189/jlb.0804460. PMID 15548573

    VCAM-1

    VCAM-1

    VCAM-1

  • Collagen, type IV, alpha 3
  • Protein found in humans

    composed of three alpha subunits; this gene encodes the alpha 3 subunit. These subunits are encoded by six different genes, alpha 1 through alpha 6, each of

    Collagen, type IV, alpha 3

    Collagen, type IV, alpha 3

    Collagen,_type_IV,_alpha_3

  • ADAM2
  • Protein-coding gene in humans

    "Functional classification of ADAMs based on a conserved motif for binding to integrin alpha 9beta 1: implications for sperm-egg binding and other cell interactions"

    ADAM2

    ADAM2

    ADAM2

  • TLN1
  • Protein-coding gene in the species Homo sapiens

    mediate cell-cell adhesion via the linkage of integrins to the actin cytoskeleton and in the activation of integrins. Altered expression of talin-1 has been

    TLN1

    TLN1

    TLN1

  • CD47
  • Protein-coding gene in humans

    and partners with membrane integrins and also binds the ligands thrombospondin 1 (TSP-1) and signal-regulatory protein alpha (SIRPα). CD-47 acts as a don't

    CD47

    CD47

    CD47

  • Tyrosine-protein kinase SYK
  • Enzyme

    WA (June 1997). "Thrombspondin acts via integrin-associated protein to activate the platelet integrin alphaIIbbeta3". The Journal of Biological Chemistry

    Tyrosine-protein kinase SYK

    Tyrosine-protein kinase SYK

    Tyrosine-protein_kinase_SYK

  • Alpha-actinin-4
  • Protein-coding gene in the species Homo sapiens

    1242/jcs.101.2.403. PMID 1629252. Otey CA, Pavalko FM, Burridge K (1990). "An interaction between alpha-actinin and the beta 1 integrin subunit in vitro"

    Alpha-actinin-4

    Alpha-actinin-4

    Alpha-actinin-4

  • Actinin
  • Protein factor that regulates the length of R-actin

    the connection between the actin cytoskeleton within the cell and the integrins that directly interact with the stromal ECM. Additionally, it can sense

    Actinin

    Actinin

  • CIB1
  • Protein-coding gene in humans

    protein also interacts with integrin alpha(IIb)beta(3), which may implicate this protein as a regulatory molecule for alpha(IIb)beta(3). CIB1 is a small

    CIB1

    CIB1

    CIB1

  • FLNA
  • Protein-coding gene in humans

    regulates the reorganization of the actin cytoskeleton by interacting with integrins, transmembrane receptor complexes, and secondary messengers. At least

    FLNA

    FLNA

    FLNA

  • ISG15
  • Protein found in humans

    can be detected in supernatant or blood plasma. ISG15 binds the LFA-1 integrin receptor on NK- and T-cells to potentiate their production of IFN-II, which

    ISG15

    ISG15

    ISG15

  • Norwegian Elkhound
  • Dog breed

    Chondrodysplasia Caused by a Truncating Mutation in Collagen-Binding Integrin Alpha Subunit 10". PLoS ONE. 8 (9) e75621. Public Library of Science (PLoS)

    Norwegian Elkhound

    Norwegian Elkhound

    Norwegian_Elkhound

  • PTK2
  • Protein-coding gene in humans

    WA (June 1997). "Thrombspondin acts via integrin-associated protein to activate the platelet integrin alphaIIbbeta3". The Journal of Biological Chemistry

    PTK2

    PTK2

    PTK2

  • Human metapneumovirus
  • Species of virus

    the F protein has been proven by its ability to bind to host cells via integrin αvβ1 using an Arginine-Glycine-Aspartate (RGD) motif, which is speculated

    Human metapneumovirus

    Human metapneumovirus

    Human_metapneumovirus

  • Juxtacrine signalling
  • Contact-based cell-cell signalling

    cell communication. Cells use mainly the receptor integrin to interact with ECM proteins. Integrins are a family of receptor proteins that integrate the

    Juxtacrine signalling

    Juxtacrine signalling

    Juxtacrine_signalling

  • ICAM3
  • Mammalian protein found in Homo sapiens

    immune system. ICAM3 mediates adhesion between cells by binding to specific integrin receptors. It plays an important role in the immune cell response through

    ICAM3

    ICAM3

    ICAM3

  • List of MeSH codes (D12.776.543)
  • – tacrolimus binding protein 1a MeSH D12.776.543.750.705.408.100 – integrin alpha chains MeSH D12.776.543.750.705.408.100.100 – antigens, cd11a MeSH D12

    List of MeSH codes (D12.776.543)

    List_of_MeSH_codes_(D12.776.543)

  • Laminin, beta 2
  • Protein-coding gene in the species Homo sapiens

    2000). "Integrin binding specificity of laminin-10/11: laminin-10/11 are recognized by alpha 3 beta 1, alpha 6 beta 1 and alpha 6 beta 4 integrins". Journal

    Laminin, beta 2

    Laminin, beta 2

    Laminin,_beta_2

  • Vitronectin
  • Protein

    bone. In humans it is encoded by the VTN gene. Vitronectin binds to integrin alpha-V beta-3 and thus promotes cell adhesion and spreading. It also inhibits

    Vitronectin

    Vitronectin

    Vitronectin

AI & ChatGPT searchs for online references containing INTEGRIN ALPHA-2

INTEGRIN ALPHA-2

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INTEGRIN ALPHA-2

  • ALPHA
  • Male

    African

    ALPHA

    (ox); the first letter of the Greek alphabet.

    ALPHA

  • Shafana |
  • Girl/Female

    Muslim

    Shafana |

    Integrity and virtuous

    Shafana |

  • Salamah
  • Boy/Male

    Arabic, Muslim

    Salamah

    Soundness; Integrity

    Salamah

  • Sahbyada
  • Girl/Female

    Indian

    Sahbyada

    Trust; Integrity

    Sahbyada

  • Duck-young
  • Boy/Male

    Korean

    Duck-young

    Integrity lasts.

    Duck-young

  • Salaamat
  • Boy/Male

    Arabic

    Salaamat

    Soundness; Integrity

    Salaamat

  • Alpha
  • Girl/Female

    Greek American

    Alpha

    Firstbom.' The first letter of the Greek alphabet.

    Alpha

  • Aliha
  • Girl/Female

    Arabic

    Aliha

    Respectable

    Aliha

  • Salamat
  • Boy/Male

    Muslim

    Salamat

    Soundness. Integrity.

    Salamat

  • Altha
  • Girl/Female

    American, British, English, Greek

    Altha

    Healer; With Healing Power

    Altha

  • Duck-hwan
  • Boy/Male

    Korean

    Duck-hwan

    Integrity returns.

    Duck-hwan

  • Alpha
  • Boy/Male

    Hindu

    Alpha

    First letter of the greek alphabet

    Alpha

  • Alpa
  • Girl/Female

    Gujarati, Hindu, Indian, Jain, Kannada, Malayalam, Marathi, Oriya, Sanskrit, Tamil, Telugu

    Alpa

    Little; Collection of Many Small Things

    Alpa

  • Alpha
  • Boy/Male

    African, Australian, Chinese, French, Latin, Swedish

    Alpha

    First Letter of the Greek Alphabet; Leader

    Alpha

  • Altha
  • Girl/Female

    English American

    Altha

    Healer.

    Altha

  • Dong-sun
  • Boy/Male

    Korean

    Dong-sun

    Eastern integrity.

    Dong-sun

  • Salamah
  • Boy/Male

    Muslim/Islamic

    Salamah

    Soundness integrity

    Salamah

  • Zameer
  • Boy/Male

    Afghan, Arabic, Bengali, Indian, Malayalam, Muslim, Pashtun, Punjabi, Sikh, Telugu

    Zameer

    Conscience; Integrity

    Zameer

  • Alphu
  • Girl/Female

    Indian

    Alphu

    Loving

    Alphu

  • Alpa
  • Girl/Female

    Indian

    Alpa

    Little

    Alpa

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Online names & meanings

  • Kerenhappuch
  • Girl/Female

    Hebrew

    Kerenhappuch

    Horn of antimony (Antimony was used in ancient times as a cosmetic).

  • Anasooya
  • Girl/Female

    Bengali, Hindu, Indian, Kannada, Mythological, Sanskrit

    Anasooya

    Wife of Rishi Atri

  • Sa'id
  • Boy/Male

    Muslim

    Sa'id

    Happy. Lucky. Rivulet.

  • Tarrence
  • Boy/Male

    American, British, English, Latin

    Tarrence

    Smooth; Roman Clan Name

  • Khashar |
  • Girl/Female

    Muslim

    Khashar |

    Decorated, Ornamented

  • ANUCIS
  • Female

    Egyptian

    ANUCIS

    , Anka.

  • Sharan
  • Boy/Male

    Christian, Gujarati, Hindu, Indian, Kannada, Malayalam, Marathi, Punjabi, Sikh, Sindhi, Tamil, Telugu

    Sharan

    Shelter

  • Amaravathy
  • Girl/Female

    Gujarati, Indian, Kannada, Marathi, Traditional

    Amaravathy

    Flowing River

  • Antini
  • Girl/Female

    Bengali, Gujarati, Hindu, Indian, Kannada, Marathi, Telugu

    Antini

    Living in a Hermitage

  • Naila
  • Girl/Female

    Indian

    Naila

    Acquirer, Obtained

AI search & ChatGPT queriess for Facebook and twitter users, user names, hashtags with INTEGRIN ALPHA-2

INTEGRIN ALPHA-2

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Other words and meanings similar to

INTEGRIN ALPHA-2

AI search in online dictionary sources & meanings containing INTEGRIN ALPHA-2

INTEGRIN ALPHA-2

  • Entireness
  • n.

    Integrity; wholeness of heart; honesty.

  • Alpha
  • n.

    The first letter in the Greek alphabet, answering to A, and hence used to denote the beginning.

  • Integral
  • a.

    Lacking nothing of completeness; complete; perfect; uninjured; whole; entire.

  • Alpia
  • n.

    The seed of canary grass (Phalaris Canariensis), used for feeding cage birds.

  • Integral
  • a.

    Pertaining to, or proceeding by, integration; as, the integral calculus.

  • Integrity
  • n.

    The state or quality of being entire or complete; wholeness; entireness; unbroken state; as, the integrity of an empire or territory.

  • Integrity
  • n.

    Moral soundness; honesty; freedom from corrupting influence or motive; -- used especially with reference to the fulfillment of contracts, the discharge of agencies, trusts, and the like; uprightness; rectitude.

  • Integral
  • n.

    An expression which, being differentiated, will produce a given differential. See differential Differential, and Integration. Cf. Fluent.

  • Integrity
  • n.

    Unimpaired, unadulterated, or genuine state; entire correspondence with an original condition; purity.

  • Integral
  • n.

    A whole; an entire thing; a whole number; an individual.

  • Interring
  • p. pr. & vb. n.

    of Inter

  • True-blue
  • n.

    A person of inflexible integrity or fidelity.

  • Integral
  • a.

    Of, pertaining to, or being, a whole number or undivided quantity; not fractional.

  • Omega
  • n.

    The last letter of the Greek alphabet. See Alpha.

  • Incorruptness
  • n.

    Probity; integrity; honesty.

  • Integral
  • a.

    Essential to completeness; constituent, as a part; pertaining to, or serving to form, an integer; integrant.

  • Intern
  • a.

    To put for safe keeping in the interior of a place or country; to confine to one locality; as, to intern troops which have fled for refuge to a neutral country.

  • Integrant
  • a.

    Making part of a whole; necessary to constitute an entire thing; integral.

  • Lyra
  • n.

    A northern constellation, the Harp, containing a white star of the first magnitude, called Alpha Lyrae, or Vega.

  • Alpist
  • n.

    Alt. of Alpia