AI & ChatGPT searches , social queries for INTEGRIN BETA-5
Search references for INTEGRIN BETA-5. Phrases containing INTEGRIN BETA-5
See searches and references containing INTEGRIN BETA-5!
Search references for INTEGRIN BETA-5. Phrases containing INTEGRIN BETA-5
See searches and references containing INTEGRIN BETA-5!INTEGRIN BETA-5
Protein-coding gene in the species Homo sapiens
Integrin beta-5 is a protein that in humans is encoded by the ITGB5 gene. Integrin, beta 5 has been shown to interact with PTK2, Annexin A5 and PAK4. ITGB5
Integrin_beta_5
Protein-coding gene in the species Homo sapiens
Integrin beta-6 is a protein that in humans is encoded by the ITGB6 gene. It is the β6 subunit of the integrin αvβ6. Integrins are αβ heterodimeric glycoproteins
Integrin_beta_6
Mammalian protein found in Homo sapiens
In molecular biology, CD18 (Integrin beta chain-2) is an integrin beta chain protein that is encoded by the ITGB2 gene in humans. Upon binding with one
Integrin_beta_2
Mammalian protein found in Homo sapiens
Integrin beta-3 (β3) or CD61 is a protein that in humans is encoded by the ITGB3 gene. CD61 is a cluster of differentiation found on thrombocytes. The
Integrin_beta_3
Mammalian protein found in Homo sapiens
Integrin beta-1 (ITGB1), also known as CD29, is a cell surface receptor that in humans is encoded by the ITGB1 gene. This integrin associates with integrin
Integrin_beta_1
Integrin beta-7 is an integrin protein that in humans is encoded by the ITGB7 gene. It can pair with ITGA4 (CD49d) to form the heterodimeric integrin
Integrin_beta_7
Protein-coding gene in the species Homo sapiens
Integrin, beta 4 (ITGB4) also known as CD104 (Cluster of Differentiation 104), is a human gene. Integrins are heterodimers composed of alpha and beta
Integrin_beta_4
Protein
family. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This gene encodes the integrin alpha 5 chain
Integrin_alpha_5
Mammalian protein found in Homo sapiens
protein. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This protein combines with the beta 2 chain
Integrin_alpha_X
Transmembrane receptors involved in cellular adhesion and signalling
Integrins are transmembrane receptors that help cell–cell and cell–extracellular matrix (ECM) adhesion. Upon ligand binding, integrins activate signal
Integrin
Protein-coding gene in the species Homo sapiens
encoded by the ITGAE gene. CD103 binds integrin beta 7 (β7– ITGB7) to form the complete heterodimeric integrin molecule αEβ7, which has no distinct name
Integrin_alpha_E
Mammalian protein found in Homo sapiens
Integrin alpha-3 is a protein that in humans is encoded by the ITGA3 gene. ITGA3 is an integrin alpha subunit. Together with beta-1 subunit, it makes
Integrin_alpha_3
It consists of two components, integrin alpha V and integrin beta 5. Sheppard D (October 2002). "Endothelial integrins and angiogenesis: not so simple
Alpha-v_beta-5
Mammalian protein found in Homo sapiens
Integrin alpha-IIb is a protein that in humans is encoded by the ITGA2B gene. ITGA2B, also known as CD41, encodes integrin alpha chain 2b. Integrins are
Integrin_alpha_2b
αVβ3 is a type of integrin that is a receptor for vitronectin. It consists of two components, integrin alpha V and integrin beta 3 (CD61), and is expressed
Alpha-v_beta-3
Topics referred to by the same term
5 (Power Rangers), a fictional character from the Power Rangers franchise Integrin alpha-5, a protein encoded by the ITGA5 gen in humans Alpha-5 beta-1
Alpha_5
Mammalian protein found in Homo sapiens
alpha 6 may combine with beta 4 in the integrin referred to as TSP180, or with beta 1 in the integrin VLA-6. Integrins are known to participate in cell adhesion
Integrin_alpha_6
Mammalian protein found in Homo sapiens
common beta chain. They are found on a wide variety of cell types including T cells (the NKT cells), NK cells, fibroblasts and platelets. Integrins are involved
Integrin_alpha_2
Mammalian protein found in Homo sapiens
alpha chain family of proteins. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This gene encodes an alpha
Integrin_alpha_4
Protein-coding gene in the species Homo sapiens
Integrin subunit beta like 1 is a protein that in humans is encoded by the ITGBL1 gene. This gene encodes a beta integrin-related protein that is a member
Integrin_subunit_beta_like_1
Protein-coding gene in the species Homo sapiens
soluble integrin-alkaline phosphatase chimera to characterize integrin alpha 8 beta 1 receptor interactions with tenascin: murine alpha 8 beta 1 binds
Integrin_alpha_8
Protein-coding gene in the species Homo sapiens
encodes an alpha integrin. Integrins are heterodimeric integral membrane glycoproteins composed of an alpha chain and a beta chain that mediate cell-cell
Integrin_alpha_9
Mammalian protein found in Homo sapiens
Integrin alpha M (ITGAM) is one protein subunit that forms heterodimeric integrin alpha-M beta-2 (αMβ2) molecule, also known as macrophage-1 antigen (Mac-1)
Integrin_alpha_M
Mammalian protein found in Homo sapiens
beta chain. Alpha V undergoes post-translational cleavage to yield disulfide-linked heavy and light chains, that combine with multiple integrin beta chains
Integrin_alpha_V
Mammalian protein found in Homo sapiens
beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form the integrin lymphocyte function-associated antigen-1
Integrin_alpha_L
join with beta 1 to form an integrin that binds to the extracellular matrix protein laminin-1. The primary binding partners of alpha-7 integrin are laminin-1
Integrin_alpha_7
Protein-coding gene in the species Homo sapiens
"Cloning and chromosomal localization of a novel gene-encoding a human beta 2-integrin alpha subunit". Gene. 171 (2): 291–4. doi:10.1016/0378-1119(95)00869-1
Integrin_alpha_D
Integrin complex found on platelets
medicine, glycoprotein IIb/IIIa (GPIIb/IIIa, also known as integrin αIIbβ3) is an integrin complex found on platelets. It is a transmembrane receptor
Glycoprotein_IIb/IIIa
Protein-coding gene in the species Homo sapiens
(May 2003). "Alpha v beta 5 integrin-dependent programmed cell death triggered by a peptide mimic of annexin V". Molecular Cell. 11 (5): 1151–62. doi:10
Annexin_A5
Cytokine
et al. (May 1996). "Inactivation of the integrin beta 6 subunit gene reveals a role of epithelial integrins in regulating inflammation in the lung and
Transforming growth factor beta
Transforming_growth_factor_beta
Protein found in humans
catalytic domain. Integrins lack enzymatic activity and depend on adapters to signal proteins. ILK is linked to beta-1 and beta-3 integrin cytoplasmic domains
Integrin-linked_kinase
Medication used for the treatment of gastro-intestinal diseases
to integrin α4β7 (LPAM-1, lymphocyte Peyer's patch adhesion molecule 1, a dimer of Integrin alpha-4 and Integrin beta-7), blocking the α4β7 integrin results
Vedolizumab
Protein-coding gene in the species Homo sapiens
an alpha chain and a beta chain. This protein contains an I domain, is expressed in muscle tissue, dimerizes with beta 1 integrin in vitro, and appears
Integrin_alpha_11
Mammalian protein found in Homo sapiens
collagen. ITGA1 noncovalently associates with the Beta-1 (β1) integrin subunit to form the α1β1 integrin heterodimer, which is a cell-surface receptor also
Integrin_alpha-1
Surface glycoproteins involved in hemostasis
Calvete JJ (1995). "On the structure and function of platelet integrin alpha IIb beta 3, the fibrinogen receptor". Proc. Soc. Exp. Biol. Med. 208 (4):
Platelet membrane glycoprotein
Platelet_membrane_glycoprotein
Contrast agent for cancer imaging
(LAP) in its complex with transforming growth factor beta 1 (TGF-β1). Binding of αvβ6-integrin to LAP releases and thus, activates TGF-β1. In early-stage
Ga-68-Trivehexin
Sheppard, D. (1996). "Inactivation of the integrin beta 6 subunit gene reveals a role of epithelial integrins in regulating inflammation in the lung and
TGF_beta_Activation
American immunologist
H.; Calderwood, D. A. (2003). "Talin binding to integrin beta tails: a final common step in integrin activation". Science. 302 (5642): 103–106. Bibcode:2003Sci
Timothy_A._Springer
Protein-coding gene in the species Homo sapiens
(December 1995). "Beta 3-endonexin, a novel polypeptide that interacts specifically with the cytoplasmic tail of the integrin beta 3 subunit". J Cell
ITGB3BP
α5β1, also known as the fibronectin receptor, is an integrin that binds to matrix macromolecules and proteinases and thereby stimulates angiogenesis. It
Alpha-5_beta-1
Integrin found on lymphocytes
Lymphocyte function-associated antigen 1 (LFA-1) is an integrin found on lymphocytes and other leukocytes. LFA-1 plays a key role in emigration, which
Lymphocyte function-associated antigen 1
Lymphocyte_function-associated_antigen_1
Protein found in humans
Ugarova TP, Ye RD, Lau LF, Lam SC (June 2002). "Identification of integrin alpha(M)beta(2) as an adhesion receptor on peripheral blood monocytes for Cyr61
CCN_family_member_2
Proteins from viper venom inhibiting platelets aggregation
clumping of platelets. They interact with the beta-1 and -3 families of integrins receptors. Integrins are cell receptors involved in cell–cell and cell–extracellular
Disintegrin
Protein-coding gene in the species Homo sapiens
containing alpha 10 combines with the integrin beta 1 chain (ITGB1) to form a novel collagen type II-binding integrin expressed in cartilage tissue. TAR
Integrin_alpha_10
Mammalian protein found in Homo sapiens
expressed on endothelial cells and cells of the immune system. It binds to integrins of type CD11a / CD18, or CD11b / CD18 and is also exploited by rhinovirus
ICAM-1
Protein-coding gene in the species Homo sapiens
POSTN gene. Periostin functions as a ligand for alpha-V/beta-3 and alpha-V/beta-5 integrins to support adhesion and migration of epithelial cells. Periostin
Periostin
Medical treatment
trials for Crohn's disease. Etrolizumab is an integrin receptor antagonist that targets beta 7 integrins. Etrolizumab has shown efficacy in phase 2 trials
Biological therapy for inflammatory bowel disease
Biological_therapy_for_inflammatory_bowel_disease
Protein-coding gene in humans
affect myogenesis, subcellular distribution, and determine binding to integrin [beta] subunits". The Journal of Cell Biology. 156 (2): 361–376. doi:10.1083/jcb
Filamin-A
Protein-coding gene in the species Homo sapiens
Integrin beta-1-binding protein 1 is a protein that in humans is encoded by the ITGB1BP1 gene. The cytoplasmic domains of integrins are essential for
ITGB1BP1
Protein-coding gene in the species Homo sapiens
recognized by alpha 3 beta 1, alpha 6 beta 1 and alpha 6 beta 4 integrins". Journal of Cell Science. 113 (5): 869–76. doi:10.1242/jcs.113.5.869. PMID 10671376
Laminin,_beta_2
Protein-coding gene in humans
egg alpha6beta1 integrin is the receptor for sperm fertilinbeta". Chemistry & Biology. 6 (1): 1–10. doi:10.1016/S1074-5521(99)80015-5. PMID 9889149. Vidaeus
ADAM2
Protein found in humans
demonstrates structural and functional similarities to the alpha 4 beta 7-integrin binding domains of murine MAdCAM-1, but extreme divergence of mucin-like
Addressin
Protein-coding gene in the species Homo sapiens
2000). "Integrin binding specificity of laminin-10/11: laminin-10/11 are recognized by alpha 3 beta 1, alpha 6 beta 1 and alpha 6 beta 4 integrins". Journal
Laminin,_alpha_5
Conversion of mechanical stimulus of a cell into electrochemical activity
extracellular matrix ligands, integrins are also receptive to autocrine and paracrine signals such as growth factors in the TGF-beta family. Chondrocytes have
Mechanotransduction
Protein family
The transforming growth factor beta (TGF-β) superfamily is a large group of structurally related cell regulatory proteins that was named after its first
Transforming growth factor beta superfamily
Transforming_growth_factor_beta_superfamily
Contact-based cell-cell signalling
cell communication. Cells use mainly the receptor integrin to interact with ECM proteins. Integrins are a family of receptor proteins that integrate the
Juxtacrine_signalling
Protein-coding gene in the species Homo sapiens
Lam SC (Oct 1999). "Identification of a talin-binding site in the integrin beta(3) subunit distinct from the NPLY regulatory motif of post-ligand binding
TLN1
Subset of cell adhesion proteins
transcription. Integrins are heterodimeric, as they consist of an alpha and beta subunit. There are currently 18 alpha subunits and 8 beta subunits, which
Cell_adhesion_molecule
Protein in the extracellular matrix
275 (5): 725–730. doi:10.1006/jmbi.1997.1510. PMID 9480764. Nieuwenhuis B, Haenzi B, Andrews MR, Verhaagen J, Fawcett JW (August 2018). "Integrins promote
Laminin
Protein-coding gene in the species Homo sapiens
S2CID 45122439. Sheppard D (September 2005). "Integrin-mediated activation of latent transforming growth factor beta". Cancer Metastasis Reviews. 24 (3): 395–402
TGF_beta_1
Protein-coding gene in the species Homo sapiens
affect myogenesis, subcellular distribution, and determine binding to integrin [beta] subunits". J. Cell Biol. 156 (2). United States: 361–76. doi:10.1083/jcb
Filamin-B
Human protein-encoding gene
outgrowth and cell migration in vitro and is associated with the alpha 6/beta 1 integrin and the neural adhesion molecule L1". Journal of Neuroscience Research
CD9
Protein found in humans
presumed through a direct association with the cytoplasmic tail of beta-integrin. The N-terminal region of paxillin is rich in protein–protein interaction
Paxillin
Human protein-coding gene
J, Balmes J, Sheppard D (May 1995). "Distribution of integrins alpha v beta 6 and alpha 9 beta 1 and their known ligands, fibronectin and tenascin, in
Tenascin_C
Protein-coding gene in humans
interact with the beta-1 integrin subunit in vitro and is thought to be involved in the transduction of signals from ECM-integrin clusters. However,
PTK2
Protein-coding gene in the species Homo sapiens
β(2) integrin function depend on both cell type (Natural killer cell or Leukocytes) and the integrin activation stimulus. The prevention of the beta-3 activation
FERMT3
Macrophage found in the lungs
inducing the expression of the αvβ6 integrin. Integrins are dimeric cell-surface receptors composed of alpha and beta subunits, which activates TGF-β. TGF-β
Alveolar_macrophage
Mammalian protein found in humans
Non-small-cell lung carcinoma Prostate cancer Homotrimer Lipid raft Integrin, beta 1 GRCh38: Ensembl release 89: ENSG00000050767 – Ensembl, May 2017 GRCm38:
Collagen,_type_XXIII,_alpha_1
Signaling pathway involving transforming growth factor beta proteins
The transforming growth factor beta (TGFβ) signaling pathway is involved in many cellular processes in both the adult organism and the developing embryo
TGF_beta_signaling_pathway
Medication used to treat multiple sclerosis and Crohn's disease
a humanized monoclonal antibody against the cell adhesion molecule α4-integrin. It is given by intravenous infusion. The drug is believed to work by reducing
Natalizumab
Protein-coding gene in humans
CD47 (Cluster of Differentiation 47) also known as integrin associated protein (IAP) is a transmembrane protein that in humans is encoded by the CD47 gene
CD47
Type of chemical bond
particle, integrin alpha L beta 2 and intercellular adhesion molecule 1 (ICAM-1), integrin alpha 4 beta 1 with vascular adhesion molecule 1, integrin alpha
Catch_bond
Protein-coding gene in the species Homo sapiens
"Interaction of alphaPIX (ARHGEF6) with beta-parvin (PARVB) suggests an involvement of alphaPIX in integrin-mediated signaling". Hum. Mol. Genet. 12
PARVB
Enzyme
Dib K (March 2003). "Fgr but not Syk tyrosine kinase is a target for beta 2 integrin-induced c-Cbl-mediated ubiquitination in adherent human neutrophils"
Tyrosine-protein_kinase_SYK
Protein-coding gene in the species Homo sapiens
Sheetz MP (Sep 2009). "Clustering of alpha(5)beta(1) integrins determines adhesion strength whereas alpha(v)beta(3) and talin enable mechanotransduction"
TLN2
Protein-coding gene in humans
(ADAM-9/Meltrin gamma) functions as an adhesion molecule by binding the alpha(v)beta(5) integrin". Biochem. Biophys. Res. Commun. 280 (2): 574–80. doi:10.1006/bbrc
ADAM9
Component of striated muscle cells
dystrophin-glycoprotein complex (DGC) and the integrin-vinculin-talin complex. The sarcoglycans of the DGC and the integrins of the integrin-vinculin-talin complex attach
Costamere
Type of proteins
alpha (Gα), beta (Gβ) and gamma (Gγ) subunits. In addition, the beta and gamma subunits can form a stable dimeric complex referred to as the beta-gamma complex
G_protein
Mammalian protein found in humans
associates with transmembrane 4 superfamily members, CD9 and CD81, and with beta 1 integrins in human melanoma". Biochem. Biophys. Res. Commun. 222 (1): 13–8. Bibcode:1996BBRC
CD81
Protein-coding gene in the species Homo sapiens
Transforming growth factor-beta 2 (TGF-β2) is a secreted protein known as a cytokine that performs many cellular functions and has a vital role during
TGF_beta_2
Exocrine gland in humans and other mammals
sub-locally. Important players include beta-1 integrin, epidermal growth factor receptor (EGFR), laminin-1/5, collagen-IV, matrix metalloproteinase (MMPs)
Mammary_gland
Mammalian protein found in humans
specifically associated with integrin alpha 4 beta 1 (CD49d/CD29)". Journal of Immunology. 157 (5): 2039–47. doi:10.4049/jimmunol.157.5.2039. PMID 8757325. Skubitz
CD63
Chemical compound
molecule inhibitors for alphav(beta)6, alphav(beta)5, and alphav(beta)3 integrins". Journal of Medicinal Chemistry. 45 (5): 1045–51. doi:10.1021/jm0102598
Cilengitide
Mammalian protein found in humans
specifically associated with integrin alpha 4 beta 1 (CD49d/CD29)". J. Immunol. 157 (5): 2039–47. doi:10.4049/jimmunol.157.5.2039. PMID 8757325. Szöllósi
CD53
Protein domain
codistributes with concentrations of integrins in the plasma membrane. Furthermore, in vitro binding studies suggest that integrins bind to talin, although with
Talin_(protein)
Protein-coding gene in humans
associates with Pyk2 and Src to regulate Src kinase activity, alpha(v)beta(3) integrin-mediated signaling, cell adhesion, and osteoclast motility". J. Cell
PTK2B
Protein-coding gene in humans
disintegrin-like domain, this protein specifically interacts with the integrin beta chain, beta 3. It also interacts with Src family protein-tyrosine kinases
ADAM15
Mammalian protein found in Homo sapiens
Interleukin-1 beta (IL-1β) also known as leukocytic pyrogen, leukocytic endogenous mediator, mononuclear cell factor, lymphocyte activating factor and
Interleukin_1_beta
Protein-coding gene in the species Homo sapiens
"PDZ interaction sites in integrin alpha subunits. T14853, TIP/GIPC binds to a type I recognition sequence in alpha 6A/alpha 5 and a novel sequence in alpha
GIPC1
Substance that forms a complex with a biomolecule
1982). "Narcotic antagonistic potency of bivalent ligands which contain beta-naltrexamine. Evidence for bridging between proximal recognition sites".
Ligand_(biochemistry)
South Korean biochemist
the Transforming Growth Factor-beta -induced Matrix Protein beta ig-h3 That Interact with the alpha vbeta 5 Integrin". Journal of Biological Chemistry
Lee_Byung-heon_(biochemist)
Protein-coding gene in the species Homo sapiens
Bernstein CN, Sargent M, Gallatin WM, Wilkins J (October 1996). "Beta 2-integrin/intercellular adhesion molecule (ICAM) expression in the normal human
ICAM2
Protein-coding gene in the species Homo sapiens
Medicine. Li J, Mayne R, Wu C (Feb 2000). "A novel muscle-specific beta 1 integrin binding protein (MIBP) that modulates myogenic differentiation". J
ITGB1BP3
Protein involved in cell adhesion, cell growth, cell migration and differentiation
extracellular matrix that binds to membrane-spanning receptor proteins called integrins. Fibronectin also binds to other extracellular matrix proteins such as
Fibronectin
Mammalian protein found in humans
suggested to be integrins. Thy1 is one of the known ligands of beta 3 integrins. Interaction of thy1 expressed on maturing axons with beta 3 integrins expressed
CD90
Protein-coding gene in humans
protein also interacts with integrin alpha(IIb)beta(3), which may implicate this protein as a regulatory molecule for alpha(IIb)beta(3). CIB1 is a small protein
CIB1
British scientist
A; Stephens, PE; Robinson, MK; Watt, FM (2003). "A tumor-associated beta 1 integrin mutation that abrogates epithelial differentiation control". J. Cell
Fiona_Watt
not listed on hcdm Bennett JS. Structure and function of the platelet integrin alphaIIbbeta3. J Clin Invest 2005; 115:3363-9. "FITC Anti-human CD51 Antibody
List of human clusters of differentiation
List_of_human_clusters_of_differentiation
Peptides released by neurons as intercellular messengers
accumbens) Epinephrine (adrenaline) Neuropeptide Y Neurotensin Serotonin (5-HT) Substance P TRH Enkephalin Some neurons make several different peptides
Neuropeptide
Protein-coding gene in the species Homo sapiens
(2000). "Integrin binding specificity of laminin-10/11: laminin-10/11 are recognized by alpha 3 beta 1, alpha 6 beta 1 and alpha 6 beta 4 integrins". J. Cell
Laminin,_beta_1
INTEGRIN BETA-5
INTEGRIN BETA-5
INTEGRIN BETA-5
INTEGRIN BETA-5
INTEGRIN BETA-5
INTEGRIN BETA-5
INTEGRIN BETA-5
INTEGRIN BETA-5
INTEGRIN BETA-5