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Mammalian protein found in Homo sapiens
In molecular biology, CD18 (Integrin beta chain-2) is an integrin beta chain protein that is encoded by the ITGB2 gene in humans. Upon binding with one
Integrin_beta_2
Protein-coding gene in the species Homo sapiens
Integrin beta-6 is a protein that in humans is encoded by the ITGB6 gene. It is the β6 subunit of the integrin αvβ6. Integrins are αβ heterodimeric glycoproteins
Integrin_beta_6
Mammalian protein found in Homo sapiens
Integrin beta-1 (ITGB1), also known as CD29, is a cell surface receptor that in humans is encoded by the ITGB1 gene. This integrin associates with integrin
Integrin_beta_1
Mammalian protein found in Homo sapiens
Integrin beta-3 (β3) or CD61 is a protein that in humans is encoded by the ITGB3 gene. CD61 is a cluster of differentiation found on thrombocytes. The
Integrin_beta_3
Integrin beta-7 is an integrin protein that in humans is encoded by the ITGB7 gene. It can pair with ITGA4 (CD49d) to form the heterodimeric integrin
Integrin_beta_7
Protein-coding gene in the species Homo sapiens
subunit of integrin that can interact with the integrin alpha v to form the integrin alpha v beta 5 integrin heterodimer. Integrin alpha V beta 5 is a receptor
Integrin_beta_5
Transmembrane receptors involved in cellular adhesion and signalling
Integrins are transmembrane receptors that help cell–cell and cell–extracellular matrix (ECM) adhesion. Upon ligand binding, integrins activate signal
Integrin
Protein-coding gene in the species Homo sapiens
Integrin, beta 4 (ITGB4) also known as CD104 (Cluster of Differentiation 104), is a human gene. Integrins are heterodimers composed of alpha and beta
Integrin_beta_4
Protein-coding gene in the species Homo sapiens
Integrin beta-8 is a protein that in humans is encoded by the ITGB8 gene. This gene is a member of the integrin beta chain family and encodes a single-pass
Integrin_beta_8
Mammalian protein found in Homo sapiens
Integrin alpha-3 is a protein that in humans is encoded by the ITGA3 gene. ITGA3 is an integrin alpha subunit. Together with beta-1 subunit, it makes
Integrin_alpha_3
Mammalian protein found in Homo sapiens
Integrin alpha-2, or CD49b (cluster of differentiation 49b), is a protein which in humans is encoded by the CD49b gene. The CD49b protein is an integrin
Integrin_alpha_2
Mammalian protein found in Homo sapiens
protein. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This protein combines with the beta 2 chain
Integrin_alpha_X
Integrin dimer
Integrin α4β1 (very late antigen-4) is an integrin dimer. It is composed of CD49d (alpha 4) and CD29 (beta 1). The alpha 4 subunit is 155 kDa, and the
VLA-4
Mammalian protein found in Homo sapiens
alpha chain family of proteins. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This gene encodes an alpha
Integrin_alpha_4
Protein
chain family. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This gene encodes the integrin alpha 5 chain
Integrin_alpha_5
Mammalian protein found in Homo sapiens
beta chain. Alpha V undergoes post-translational cleavage to yield disulfide-linked heavy and light chains, that combine with multiple integrin beta chains
Integrin_alpha_V
Mammalian protein found in Homo sapiens
Integrin alpha M (ITGAM) is one protein subunit that forms heterodimeric integrin alpha-M beta-2 (αMβ2) molecule, also known as macrophage-1 antigen (Mac-1)
Integrin_alpha_M
Human chromosome
receptor 2 IL10RB: encoding interleukin-10 receptor subunit beta ITGB2: encoding protein integrin beta-2 ITSN1: encoding protein intersectin-1 JAM2: encoding
Chromosome_21
include the novel CAR-T therapy Kymriah and betibeglogene autotemcel for beta thalassemia. As of 31 March 2021, 62 requests for RMAT status have been granted
Regenerative medicine advanced therapy
Regenerative_medicine_advanced_therapy
Protein complex
Integrin α4β7 (Lymphocyte Peyer’s patch adhesion molecule-1) is an integrin heterodimer composed of CD49d (alpha-4) subunit and beta-7 subunit noncovalently
LPAM-1
(alpha1-beta1-gamma1), laminin-2 (alpha2-beta1-gamma1) and laminin-4 (alpha2-beta2-gamma1). Alpha-7/beta-1 is the major integrin complex expressed in differentiated
Integrin_alpha_7
Protein found in humans
catalytic domain. Integrins lack enzymatic activity and depend on adapters to signal proteins. ILK is linked to beta-1 and beta-3 integrin cytoplasmic domains
Integrin-linked_kinase
Mammalian protein found in Homo sapiens
Integrin alpha-IIb is a protein that in humans is encoded by the ITGA2B gene. ITGA2B, also known as CD41, encodes integrin alpha chain 2b. Integrins are
Integrin_alpha_2b
Protein-coding gene in the species Homo sapiens
encoded by the ITGAE gene. CD103 binds integrin beta 7 (β7– ITGB7) to form the complete heterodimeric integrin molecule αEβ7, which has no distinct name
Integrin_alpha_E
Mammalian protein found in Homo sapiens
beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form the integrin lymphocyte function-associated antigen-1
Integrin_alpha_L
Protein-coding gene in the species Homo sapiens
Integrin subunit beta like 1 is a protein that in humans is encoded by the ITGBL1 gene. This gene encodes a beta integrin-related protein that is a member
Integrin_subunit_beta_like_1
Protein-coding gene in the species Homo sapiens
encodes an alpha integrin. Integrins are heterodimeric integral membrane glycoproteins composed of an alpha chain and a beta chain that mediate cell-cell
Integrin_alpha_9
Integrin complex found on platelets
medicine, glycoprotein IIb/IIIa (GPIIb/IIIa, also known as integrin αIIbβ3) is an integrin complex found on platelets. It is a transmembrane receptor
Glycoprotein_IIb/IIIa
Species of bacterium
kills granulocytes, monocytes, and other white blood cells expressing integrin beta-2 (CD18) Cytolethal distending toxin Immunosuppression factors that inhibit
Aggregatibacter actinomycetemcomitans
Aggregatibacter_actinomycetemcomitans
Mammalian protein found in Homo sapiens
"Activation of human neutrophils induces an interaction between the integrin beta 2-subunit (CD18) and the actin binding protein alpha-actinin". Journal
Alpha-actinin-3
Mammalian protein found in Homo sapiens
Integrin alpha-1 also CD49a is an integrin alpha subunit encoded in humans by the gene ITGA1. It makes up half of the α1β1 integrin duplex. Though CD49a
Integrin_alpha-1
Protein-coding gene in the species Homo sapiens
human integrin alpha 8 subunit: a beta 1-associated alpha subunit expressed in smooth muscle cells". J Cell Sci. 108 (2): 537–44. doi:10.1242/jcs.108.2.537
Integrin_alpha_8
not listed on hcdm Bennett JS. Structure and function of the platelet integrin alphaIIbbeta3. J Clin Invest 2005; 115:3363-9. "FITC Anti-human CD51 Antibody
List of human clusters of differentiation
List_of_human_clusters_of_differentiation
Protein-coding gene in the species Homo sapiens
an alpha chain and a beta chain. This protein contains an I domain, is expressed in muscle tissue, dimerizes with beta 1 integrin in vitro, and appears
Integrin_alpha_11
Integrin protease-dependent activation mechanism Because MMP-2 and MMP-9 can activate TGF-β through proteolytic degradation of the latent TGF beta complex
TGF_beta_Activation
Protein-coding gene in the species Homo sapiens
Transforming growth factor-beta 2 (TGF-β2) is a secreted protein known as a cytokine that performs many cellular functions and has a vital role during
TGF_beta_2
Protein-coding gene in the species Homo sapiens
"Activation of human neutrophils induces an interaction between the integrin beta 2-subunit (CD18) and the actin binding protein alpha-actinin". Journal
Alpha-actinin-2
Mammalian protein found in Homo sapiens
alpha 6 may combine with beta 4 in the integrin referred to as TSP180, or with beta 1 in the integrin VLA-6. Integrins are known to participate in cell adhesion
Integrin_alpha_6
Protein-coding gene in the species Homo sapiens
chromosomal localization of a novel gene-encoding a human beta 2-integrin alpha subunit". Gene. 171 (2): 291–4. doi:10.1016/0378-1119(95)00869-1. PMID 8666289
Integrin_alpha_D
Medication used for the treatment of gastro-intestinal diseases
to integrin α4β7 (LPAM-1, lymphocyte Peyer's patch adhesion molecule 1, a dimer of Integrin alpha-4 and Integrin beta-7), blocking the α4β7 integrin results
Vedolizumab
Contrast agent for cancer imaging
(LAP) in its complex with transforming growth factor beta 1 (TGF-β1). Binding of αvβ6-integrin to LAP releases and thus, activates TGF-β1. In early-stage
Ga-68-Trivehexin
Cytokine
MMPs. Because MMP-2 and MMP-9 can activate TGF-β through proteolytic degradation of the latent TGF beta complex, αV containing integrins activate TGF-β1
Transforming growth factor beta
Transforming_growth_factor_beta
Protein-coding gene in the species Homo sapiens
"Activation of human neutrophils induces an interaction between the integrin beta 2-subunit (CD18) and the actin binding protein alpha-actinin". J. Immunol
Alpha-actinin-4
Protein domain
which are ligands for integrins. The crystal structure of this domain has been reported; it adopts an immunoglobulin-like beta-sandwich structure, with
Adhesion molecule (immunoglobulin-like)
Adhesion_molecule_(immunoglobulin-like)
Integrin found on lymphocytes
Lymphocyte function-associated antigen 1 (LFA-1) is an integrin found on lymphocytes and other leukocytes. LFA-1 plays a key role in emigration, which
Lymphocyte function-associated antigen 1
Lymphocyte_function-associated_antigen_1
Contact-based cell-cell signalling
cell communication. Cells use mainly the receptor integrin to interact with ECM proteins. Integrins are a family of receptor proteins that integrate the
Juxtacrine_signalling
Protein-coding gene in the species Homo sapiens
containing alpha 10 combines with the integrin beta 1 chain (ITGB1) to form a novel collagen type II-binding integrin expressed in cartilage tissue. TAR
Integrin_alpha_10
Type of proteins
alpha (Gα), beta (Gβ) and gamma (Gγ) subunits. In addition, the beta and gamma subunits can form a stable dimeric complex referred to as the beta-gamma complex
G_protein
Subset of cell adhesion proteins
transcription. Integrins are heterodimeric, as they consist of an alpha and beta subunit. There are currently 18 alpha subunits and 8 beta subunits, which
Cell_adhesion_molecule
Pharmaceutical compound
(MEDI-523) is a humanized monoclonal antibody against the vascular integrin alpha-v beta-3. It is shown to be a promising angiogenesis inhibitor used in
Vitaxin
Conversion of mechanical stimulus of a cell into electrochemical activity
extracellular matrix ligands, integrins are also receptive to autocrine and paracrine signals such as growth factors in the TGF-beta family. Chondrocytes have
Mechanotransduction
Mammalian protein found in Homo sapiens
expressed on endothelial cells and cells of the immune system. It binds to integrins of type CD11a / CD18, or CD11b / CD18 and is also exploited by rhinovirus
ICAM-1
Mammalian protein found in Homo sapiens
Interleukin-1 beta (IL-1β) also known as leukocytic pyrogen, leukocytic endogenous mediator, mononuclear cell factor, lymphocyte activating factor and
Interleukin_1_beta
Enzyme
is a target for beta 2 integrin-induced c-Cbl-mediated ubiquitination in adherent human neutrophils". The Biochemical Journal. 370 (Pt 2): 687–94. doi:10
Tyrosine-protein_kinase_SYK
American immunologist
interaction in inflammation: distinct roles for LECAM-1 and the leukocyte beta 2 integrins in vivo". Proceedings of the National Academy of Sciences of the United
Timothy_A._Springer
Cell cycle regulation pathway
E17K activating mutations, which is observed in 4–6% of breast cancers and 1–2% of colorectal cancer. Research towards Akt inhibition has focused on inhibition
PI3K/AKT/mTOR_pathway
Protein-coding gene in the species Homo sapiens
OSF-2) is a protein that in humans is encoded by the POSTN gene. Periostin functions as a ligand for alpha-V/beta-3 and alpha-V/beta-5 integrins to support
Periostin
Protein-coding gene in the species Homo sapiens
S2CID 45122439. Sheppard D (September 2005). "Integrin-mediated activation of latent transforming growth factor beta". Cancer Metastasis Reviews. 24 (3): 395–402
TGF_beta_1
Surface glycoproteins involved in hemostasis
Calvete JJ (1995). "On the structure and function of platelet integrin alpha IIb beta 3, the fibrinogen receptor". Proc. Soc. Exp. Biol. Med. 208 (4):
Platelet membrane glycoprotein
Platelet_membrane_glycoprotein
Structures which transmit force and signals between a cell and the extracellular matrix
the DGEA and GFOGER motifs found in collagen. Integrins are heterodimers which are formed from one beta and one alpha subunit. These subunits are present
Focal_adhesion
Medication used to treat multiple sclerosis and Crohn's disease
a humanized monoclonal antibody against the cell adhesion molecule α4-integrin. It is given by intravenous infusion. The drug is believed to work by reducing
Natalizumab
Signaling pathway involving transforming growth factor beta proteins
The transforming growth factor beta (TGFβ) signaling pathway is involved in many cellular processes in both the adult organism and the developing embryo
TGF_beta_signaling_pathway
Medical condition
β-2 integrin subunit, also called CD18, which is encoded by the ITGB2 gene found on chromosome 21. This subunit is involved in the formation of the β-2
Leukocyte_adhesion_deficiency
Protein-coding gene in the species Homo sapiens
Lam SC (Oct 1999). "Identification of a talin-binding site in the integrin beta(3) subunit distinct from the NPLY regulatory motif of post-ligand binding
TLN1
Exocrine gland in humans and other mammals
cell growth or differentiation sub-locally. Important players include beta-1 integrin, epidermal growth factor receptor (EGFR), laminin-1/5, collagen-IV
Mammary_gland
Protein-coding gene in humans
Disintegrin and metalloproteinase domain-containing protein 2 or Beta-fertilin is an enzyme that in humans is encoded by the ADAM2 gene. This gene encodes
ADAM2
Cascade of intracellular and molecular events for transmission/amplification of signals
signaling is mainly orchestrated in focal adhesions, regions where the integrin-bound actin cytoskeleton detects changes and transmits them downstream
Signal_transduction
Macrophage found in the lungs
inducing the expression of the αvβ6 integrin. Integrins are dimeric cell-surface receptors composed of alpha and beta subunits, which activates TGF-β. TGF-β
Alveolar_macrophage
Protein-coding gene in the species Homo sapiens
2000). "Integrin binding specificity of laminin-10/11: laminin-10/11 are recognized by alpha 3 beta 1, alpha 6 beta 1 and alpha 6 beta 4 integrins". Journal
Laminin,_beta_2
Medical treatment
2 trials for Crohn's disease. Etrolizumab is an integrin receptor antagonist that targets beta 7 integrins. Etrolizumab has shown efficacy in phase 2
Biological therapy for inflammatory bowel disease
Biological_therapy_for_inflammatory_bowel_disease
Human protein-encoding gene
outgrowth and cell migration in vitro and is associated with the alpha 6/beta 1 integrin and the neural adhesion molecule L1". Journal of Neuroscience Research
CD9
Protein found in humans
demonstrates structural and functional similarities to the alpha 4 beta 7-integrin binding domains of murine MAdCAM-1, but extreme divergence of mucin-like
Addressin
900 – integrin alphav MeSH D12.776.543.750.705.408.100.950 – platelet membrane glycoprotein iib MeSH D12.776.543.750.705.408.200 – integrin beta chains
List of MeSH codes (D12.776.543)
List_of_MeSH_codes_(D12.776.543)
Protein family
The transforming growth factor beta (TGF-β) superfamily is a large group of structurally related cell regulatory proteins that was named after its first
Transforming growth factor beta superfamily
Transforming_growth_factor_beta_superfamily
Peptides released by neurons as intercellular messengers
protein-coupled receptors". The Journal of Cell Biology. 150 (2): F83–F88. doi:10.1083/jcb.150.2.f83. PMC 2180217. PMID 10908591. Dürrnagel S, Kuhn A, Tsiairis
Neuropeptide
Protein-coding gene in humans
interact with the beta-1 integrin subunit in vitro and is thought to be involved in the transduction of signals from ECM-integrin clusters. However,
PTK2
Protein in the extracellular matrix
secreted by Schwann cells. Neurons of the peripheral nervous system express integrin receptors that attach to laminins and promote neuroregeneration after injury
Laminin
Human protein-coding gene
attachment and spreading on human tenascin is mediated by alpha 2 beta 1 and alpha v beta 3 integrins". Journal of Cell Science. 105 (4): 1001–1012. doi:10.1242/jcs
Tenascin_C
Protein-coding gene in humans
protein also interacts with integrin alpha(IIb)beta(3), which may implicate this protein as a regulatory molecule for alpha(IIb)beta(3). CIB1 is a small protein
CIB1
Protein found in humans
presumed through a direct association with the cytoplasmic tail of beta-integrin. The N-terminal region of paxillin is rich in protein–protein interaction
Paxillin
Mammalian protein
domain. The COL3A1 gene is located on the long (q) arm of chromosome 2 at 2q32.2, between positions 188974372 and 189012745. The gene has 51 exons and
Collagen,_type_III,_alpha_1
Mammalian protein found in humans
CD81 (TAPA-1), CD82, CD63, and CD53 specifically associated with integrin alpha 4 beta 1 (CD49d/CD29)". Journal of Immunology. 157 (5): 2039–47. doi:10
CD63
Protein-coding gene in the species Homo sapiens
Integrin beta-1-binding protein 1 is a protein that in humans is encoded by the ITGB1BP1 gene. The cytoplasmic domains of integrins are essential for
ITGB1BP1
Mammalian protein found in humans
suggested to be integrins. Thy1 is one of the known ligands of beta 3 integrins. Interaction of thy1 expressed on maturing axons with beta 3 integrins expressed
CD90
Protein-coding gene in humans
CD47 (Cluster of Differentiation 47) also known as integrin associated protein (IAP) is a transmembrane protein that in humans is encoded by the CD47 gene
CD47
Protein found in humans
Ugarova TP, Ye RD, Lau LF, Lam SC (June 2002). "Identification of integrin alpha(M)beta(2) as an adhesion receptor on peripheral blood monocytes for Cyr61
Connective tissue growth factor
Connective_tissue_growth_factor
Protein Domain
"Crystal structure of the I-domain from the CD11a/CD18 (LFA-1, alpha L beta 2) integrin". Proc. Natl. Acad. Sci. U.S.A. 92 (22): 10277–81. Bibcode:1995PNAS
Von Willebrand factor type A domain
Von_Willebrand_factor_type_A_domain
Protein-coding gene in humans
associates with Pyk2 and Src to regulate Src kinase activity, alpha(v)beta(3) integrin-mediated signaling, cell adhesion, and osteoclast motility". J. Cell
PTK2B
Protein-coding gene in the species Homo sapiens
(2000). "Integrin binding specificity of laminin-10/11: laminin-10/11 are recognized by alpha 3 beta 1, alpha 6 beta 1 and alpha 6 beta 4 integrins". J. Cell
Laminin,_beta_1
Protein found in humans
"Human coxsackie-adenovirus receptor is colocalized with integrins alpha(v)beta(3) and alpha(v)beta(5) on the cardiomyocyte sarcolemma and upregulated in
Coxsackievirus and adenovirus receptor
Coxsackievirus_and_adenovirus_receptor
Protein involved in cell adhesion, cell growth, cell migration and differentiation
extracellular matrix that binds to membrane-spanning receptor proteins called integrins. Fibronectin also binds to other extracellular matrix proteins such as
Fibronectin
Series of molecular signals
single-pass transmembrane proteins and are members of the DSL (Delta/Serrate/LAG-2) family of proteins. In Drosophila melanogaster (the fruit fly), there are
Notch_signaling_pathway
switching by means of overlapping motifs (e.g. the C-terminal tails of integrin beta subunits), or they can allow high avidity interactions by multiple low
Short_linear_motif
Protein-coding gene in humans
platelet aggregation. Evidence for a mechanistic link between PECAM-1- and integrin-mediated cellular signaling". The Journal of Biological Chemistry. 272
PTPN11
Protein-coding gene in the species Homo sapiens
fibrinogen, fibronectin, laminin, collagens types V and VII and integrins alpha-V/beta-1. This protein has been shown to play roles in platelet aggregation
Thrombospondin_1
Proteins from viper venom inhibiting platelets aggregation
clumping of platelets. They interact with the beta-1 and -3 families of integrins receptors. Integrins are cell receptors involved in cell–cell and cell–extracellular
Disintegrin
Cell signaling pathway
expression of S-phase entry genes including Cyclin E, Cyclin A2 and Emi1. ERK1/2 activation downstream of mitogen induced Ras signaling is necessary and sufficient
MAPK/ERK_pathway
Protein-coding gene in the species Homo sapiens
β(2) integrin function depend on both cell type (Natural killer cell or Leukocytes) and the integrin activation stimulus. The prevention of the beta-3
FERMT3
Pore-forming toxin produced by the bacteria Staphylococcus
protein-containing receptors, typically G-protein coupled receptors, or an integrin on the host cell's surface. The S subunit then recruits a second, "F" subunit
Leukocidin
Protein domain
codistributes with concentrations of integrins in the plasma membrane. Furthermore, in vitro binding studies suggest that integrins bind to talin, although with
Talin_(protein)
INTEGRIN BETA-2
INTEGRIN BETA-2
Female
Hebrew
(× Ö¶×˜Ö·×¢) Hebrew unisex name NETA means meaning "plant, shrub."
Female
Hungarian
Hungarian form of Greek Elisabet, ERZSÉBET means "God is my oath."
Female
Spanish
 Short form of Spanish Aleta, LETA means "winged." Compare with another form of Leta.
Female
Polish
Polish form of Greek Elisabet, ELŻBIETA means "God is my oath."
Boy/Male
Scottish Shakespearean
Son of Beth.
Female
German
Short form of German Margarete, META means "pearl."
Female
English
Czech and Polish form of German Bertha, BERTA means "bright."
Boy/Male
Hindu, Indian, Sanskrit
Emperor; Single Beat
Girl/Female
Greek Hebrew English
From the Hebrew Elisheba, meaning either oath of God, or God is satisfaction. Famous bearer: Old...
Girl/Female
Indian, Marathi
Our Heart Beat
Female
English
Short form of English Elizabeth, BETH means "God is my oath."Â
Female
Polish
Polish name derived from Latin beatus, BEATA means "blessed."Â
Female
Native American
 Native American Blackfoot name PETA means "golden eagle." Compare with another form of Peta.
Biblical
Beth (Hebrew)|house of the sun
Female
English
Short form of English Elizabeth, BET means "God is my oath."Â
Boy/Male
Bengali, Hindu, Indian, Sanskrit
Heart Beat
Female
English
Short form of English Beatrix, BEA means "voyager (through life)."Â
Female
Italian
 Variant spelling of Italian Zita, ZETA means "little girl." Compare with another form of Zeta.
Male
Hebrew
(בֶּלַע) Hebrew name BELA means "destruction." In the bible, this is the name of several characters, including a king of Edom.
Female
English
English name derived from the second letter of the Greek alphabet, beta, related to Hebrew bet, BETA means "house."Â
INTEGRIN BETA-2
INTEGRIN BETA-2
Boy/Male
Hindu, Indian
Lord Krishna
Girl/Female
Indian
Lit by the Moon
Girl/Female
American, British, English
Sea of Bitterness; Variant of Mary; Bitter; Often Used as English Surname
Female
Welsh
Welsh name, possibly GWENHWYVACH means "Gwengwy the less." In Arthurian legend, this is the name of the sister of Guinevere (Gwenhwyvar). She may have been wife to Mordred.
Boy/Male
Tamil
Fearful
Male
Croatian
, cross of peace.
Boy/Male
Hindu, Indian
Open
Boy/Male
British, Christian, English, Latin
Sage; Counsel from the Elves; Elf Counsel
Boy/Male
Hindu, Indian, Punjabi, Sikh
Full of Strength
Boy/Male
Indian
Calm; Variant of Sara and Serene Serene
INTEGRIN BETA-2
INTEGRIN BETA-2
INTEGRIN BETA-2
INTEGRIN BETA-2
INTEGRIN BETA-2
v. t.
To strike repeatedly; to lay repeated blows upon; as, to beat one's breast; to beat iron so as to shape it; to beat grain, in order to force out the seeds; to beat eggs and sugar; to beat a drum.
p. p.
of Beat
n.
The state or quality of being entire or complete; wholeness; entireness; unbroken state; as, the integrity of an empire or territory.
a.
Making part of a whole; necessary to constitute an entire thing; integral.
imp. & p. p.
of Bet
a.
Pertaining to, or proceeding by, integration; as, the integral calculus.
v. t.
To give the signal for, by beat of drum; to sound by beat of drum; as, to beat an alarm, a charge, a parley, a retreat; to beat the general, the reveille, the tattoo. See Alarm, Charge, Parley, etc.
imp.
of Beat
a.
Essential to completeness; constituent, as a part; pertaining to, or serving to form, an integer; integrant.
a.
To put for safe keeping in the interior of a place or country; to confine to one locality; as, to intern troops which have fled for refuge to a neutral country.
v. t.
To beat severely.
v. i.
To make a succession of strokes on a drum; as, the drummers beat to call soldiers to their quarters.
v. i.
A round or course which is frequently gone over; as, a watchman's beat.
v. i.
A cheat or swindler of the lowest grade; -- often emphasized by dead; as, a dead beat.
n.
A recurring stroke; a throb; a pulsation; as, a beat of the heart; the beat of the pulse.
v. t.
To beat thoroughly or severely.
v. i.
To make a sound when struck; as, the drums beat.
v. t.
That on which bets are laid; the subject of a bet.