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Transcription factor
repressor CTCF also known as 11-zinc finger protein or CCCTC-binding factor is a transcription factor that in humans is encoded by the CTCF gene. CTCF is involved
CTCF
Genetic boundary element that blocks the interaction between enhancers and promoters
many examples of insulators, including the CTCF insulator, the gypsy insulator, and the β-globin locus. The CTCF insulator is especially important in vertebrates
Insulator_(genetics)
Self-interacting genomic region
and even across species and are highly enriched with CCCTC-binding factor (CTCF) and cohesin. In addition, some types of genes (such as transfer RNA genes
Topologically associating domain
Topologically_associating_domain
Medium security prison in Cañon City, Colorado
Colorado Territorial Correctional Facility (CTCF), colloquially known simply as "Territorial" and formerly known as the Colorado State Prison, is a medium
Colorado Territorial Correctional Facility
Colorado_Territorial_Correctional_Facility
Complex of DNA and protein in eukaryotic cells
the complex itself. CTCF, a transcription factor that limits the frontier of the DNA loop. To stop the growth of a loop, two CTCF molecules must be positioned
Chromatin
Mechanism of nuclear organization
road-block that can be randomly encountered on the DNA. CTCF: The C-terminal DNA-binding domain of CTCF has been shown to directly interact with SA2 and SCC1
Loop_extrusion
Protein complex that regulates the separation of sister chromatids during cell division
interactions by bridging them in cis. Cohesin connecting CTCF sites in cis by interacting with CTCFs in a highly specific and oriented manner. Cohesin creating
Cohesin
DXZ4 is composed of 3kb monomers containing a highly conserved CTCF binding site. CTCF is a transcription factor protein and the main insulator responsible
DXZ4
CCCTC-binding factor (CTCF) is a zinc finger protein which occurs naturally in some human cells. CTCF is localized to the nucleus of cells. CTCF has been shown
HHV latency associated transcript
HHV_latency_associated_transcript
Adaptive immunity variety-generation process
can occur in many places), but more importantly on chromatin interaction. CTCF-binding elements (CBEs) are another key feature of V(D)J-recombining loci
V(D)J_recombination
Negative regulation (or limiting) of body weight and cell proliferation
determined that the later-replicating maternal H19 allele is CTCF-bound, and that it is this CTCF binding that determines the time of H19 replication. Evidence
H19_(gene)
Protein hormone
three DNA sequences bind to CTCF in a way that limits downstream enhancer access to the IGF2 region. The mechanism in which CTCF binds to these regions is
Insulin-like_growth_factor_2
Protein-coding gene in the species Homo sapiens
factor (CTCF), an 11-zinc finger factor involved in gene regulation, utilizes different zinc fingers to bind varying DNA target sites. CTCF forms methylation-sensitive
CTCFL
Medical condition
removed, eliminating three CCCTC-binding factor (CTCF) sites. CTCF sites are where CTCF proteins bind. CTCF proteins help organize the genome by forming a
Acheiropodia
In mammals, insulators are bound by CTCF, but only a minority of CTCF-bound sites function as insulators. CTCF molecules can form homodimers on DNA,
Insulated_neighborhood
Family of proteins
death pathway has been activated. [citation needed] CCCTC-binding factor (CTCF) induces PAR accumulation. ADP-ribose polymers, either free or PARP1 bound
Poly_(ADP-ribose)_polymerase
Process of copying a segment of DNA into RNA
The loop is stabilized by a dimer of a connector protein (e.g. dimer of CTCF or YY1), with one member of the dimer anchored to its binding motif on the
Transcription_(biology)
Geneticist
CTCF and cohesin function in ESCs. Work from his lab suggests that sperm chromatin may not be as inert as previously thought, and that RNAPII, CTCF,
Victor_Corces
Regulatory protein in bacteria
TFIID TFIIE 1 2 TFIIF 1 2 TFIIH 1 2 4 2I 3A 3C1 3C2 ATBF1 BCL 6 11A 11B CTCF E4F1 EGR 1 2 3 4 ERV3 GFI1 GLI family 1 2 3 REST S1 S2 YY1 HIC 1 2 HIVEP
CAMP_receptor_protein
Protein molecule receiving signals for a cell
TFIID TFIIE 1 2 TFIIF 1 2 TFIIH 1 2 4 2I 3A 3C1 3C2 ATBF1 BCL 6 11A 11B CTCF E4F1 EGR 1 2 3 4 ERV3 GFI1 GLI family 1 2 3 REST S1 S2 YY1 HIC 1 2 HIVEP
Receptor_(biochemistry)
Genomic analysis technique
TADs, the researchers discovered increases in the number of DHS sites, CTCF binding ability, active histone modifications, and target gene expressions
Hi-C (genomic analysis technique)
Hi-C_(genomic_analysis_technique)
American geneticist and molecular biologist (1929–2024)
interactions between enhancers and promoters. He discovered that the protein CTCF functions as a major genomic boundary element, playing a crucial role in
Gary_Felsenfeld
Spatial distribution of chromatin within a cell nucleus
active in regulating CTCF binding and therefore affect genome organization and transcription of many genes. CCCTC-binding factor (CTCF), or 11-zinc finger
Nuclear_organization
2018 Italian-American television series
"Ascolti tv domenica 20 febbraio 2022: L'amica geniale, Che bella giornata, CTCF". TvBlog (in Italian). Archived from the original on February 21, 2022. Retrieved
My Brilliant Friend (TV series)
My_Brilliant_Friend_(TV_series)
Protein that regulates the rate of DNA transcription
TFIID TFIIE 1 2 TFIIF 1 2 TFIIH 1 2 4 2I 3A 3C1 3C2 ATBF1 BCL 6 11A 11B CTCF E4F1 EGR 1 2 3 4 ERV3 GFI1 GLI family 1 2 3 REST S1 S2 YY1 HIC 1 2 HIVEP
Transcription_factor
Study of DNA modifications that do not change its sequence
2014). "Nucleosome repositioning links DNA (de)methylation and differential CTCF binding during stem cell development". Genome Research. 24 (8): 1285–95.
Epigenetics
Method in molecular biology
also identified the first clear evidence of CTCF-Cohesin looping in Hi-C maps and identified the convergent CTCF motif rule underlying these loops. In 2018
Chromosome conformation capture
Chromosome_conformation_capture
Protein-coding gene in humans
PMC 517884. PMID 15456888. Ishihara K, Oshimura M, Nakao M (September 2006). "CTCF-dependent chromatin insulator is linked to epigenetic remodeling". Molecular
CHD8
Brazilian higher education institution
was built and, attached to it, the Technical School of Coronel Fabriciano (CTCF) - now the Padre de Man School. Thus, the complex became the first technical
Catholic University Center of Eastern Minas Gerais
Catholic_University_Center_of_Eastern_Minas_Gerais
JD, Bhattacharya A, Cui Y (January 2013). "CTCFBSDB 2.0: a database for CTCF-binding sites and genome organization". Nucleic Acids Research. 41 (Database
Transcription factor binding site databases
Transcription_factor_binding_site_databases
Mammalian protein found in Homo sapiens
SP1/GC CAAT CCAAT binding factors ZF57 KRAB domain zinc finger protein 57 CTCF CTCF and BORIS gene family, transcriptional regulators with highly conserved
Cholesin
Protein structural motif
TFIID TFIIE 1 2 TFIIF 1 2 TFIIH 1 2 4 2I 3A 3C1 3C2 ATBF1 BCL 6 11A 11B CTCF E4F1 EGR 1 2 3 4 ERV3 GFI1 GLI family 1 2 3 REST S1 S2 YY1 HIC 1 2 HIVEP
Basic_helix–loop–helix
Mammalian protein found in humans
TFIID TFIIE 1 2 TFIIF 1 2 TFIIH 1 2 4 2I 3A 3C1 3C2 ATBF1 BCL 6 11A 11B CTCF E4F1 EGR 1 2 3 4 ERV3 GFI1 GLI family 1 2 3 REST S1 S2 YY1 HIC 1 2 HIVEP
P53
Region of DNA in a eukaryotic chromosome
markedly enriched for DNase I hypersensitive sites and for the binding of CTCF, the major organizer of higher-order chromatin. This observation indicates
Active_chromatin_sequence
Instance of defined set in Homo sapiens with Reactome ID (R-HSA-6806560)
TFIID TFIIE 1 2 TFIIF 1 2 TFIIH 1 2 4 2I 3A 3C1 3C2 ATBF1 BCL 6 11A 11B CTCF E4F1 EGR 1 2 3 4 ERV3 GFI1 GLI family 1 2 3 REST S1 S2 YY1 HIC 1 2 HIVEP
AP-1_transcription_factor
Protein-coding gene in the species Homo sapiens
interactions, mediated by CTCF in epidermal keratinocytes. Such hubs contain multiple connecting DNA loops that require not only CTCF binding that is rather
TP63
posttranslational histonemodification of heterochromatin. LADs are also known to have CTCF-binding sites at their periphery. Topologically associating domain Nuclear
Lamina_associated_domains
Transcription factor gene of the SOX family
TFIID TFIIE 1 2 TFIIF 1 2 TFIIH 1 2 4 2I 3A 3C1 3C2 ATBF1 BCL 6 11A 11B CTCF E4F1 EGR 1 2 3 4 ERV3 GFI1 GLI family 1 2 3 REST S1 S2 YY1 HIC 1 2 HIVEP
SOX9
Biological term
are characterized by the massive presence of insulator binding proteins CTCF. Secondly, boundary regions block heterochromatin spreading, thus preventing
Epigenome
Region of DNA encouraging transcription
The loop is stabilized by a dimer of a connector protein (e.g. dimer of CTCF or YY1), with one member of the dimer anchored to its binding motif on the
Promoter_(genetics)
Mammalian protein found in Homo sapiens
TFIID TFIIE 1 2 TFIIF 1 2 TFIIH 1 2 4 2I 3A 3C1 3C2 ATBF1 BCL 6 11A 11B CTCF E4F1 EGR 1 2 3 4 ERV3 GFI1 GLI family 1 2 3 REST S1 S2 YY1 HIC 1 2 HIVEP
Oct-4
German biologist (born 1962)
relationship between cohesin and CTCF in gene regulation. Peters and his colleagues showed that cohesin contributes to CTCF-mediated transcriptional insulation
Jan-Michael_Peters
Cytoplasmic receptor protein found inside cells
TFIID TFIIE 1 2 TFIIF 1 2 TFIIH 1 2 4 2I 3A 3C1 3C2 ATBF1 BCL 6 11A 11B CTCF E4F1 EGR 1 2 3 4 ERV3 GFI1 GLI family 1 2 3 REST S1 S2 YY1 HIC 1 2 HIVEP
Progesterone_receptor
Fibrillar network
(LADs). The average length of human LADs is 0.1–10 MBp. LADs are flanked by CTCF-binding sites. At the onset of mitosis (prophase, prometaphase), the cellular
Nuclear_lamina
TFIID TFIIE 1 2 TFIIF 1 2 TFIIH 1 2 4 2I 3A 3C1 3C2 ATBF1 BCL 6 11A 11B CTCF E4F1 EGR 1 2 3 4 ERV3 GFI1 GLI family 1 2 3 REST S1 S2 YY1 HIC 1 2 HIVEP
GSX1
American prison warden and actor
father Boon as warden of the Colorado Territorial Correctional Facility (CTCF) in Canon City. Adams later appointed Roy as warden of the same facility
Roy_Best_(prison_warden)
Protein-coding gene in the species Homo sapiens
repair. Y box binding protein 1 has been shown to interact with: ANKRD2, CTCF, P53, PCNA, RBBP6, and SFRS9. GRCh38: Ensembl release 89: ENSG00000065978
Y-box-binding_protein_1
American cell biologist
factor CTCF. She found that in the absence of CTCF, H19 becomes hypermethylated and embryos die early in development. She went on to show that CTCF was crucial
Marisa_Bartolomei
Conversion of a gene's sequence into a mature gene product or products
The loop is stabilized by a dimer of a connector protein (e.g. dimer of CTCF or YY1). One member of the dimer is anchored to its binding motif on the
Gene_expression
TFIID TFIIE 1 2 TFIIF 1 2 TFIIH 1 2 4 2I 3A 3C1 3C2 ATBF1 BCL 6 11A 11B CTCF E4F1 EGR 1 2 3 4 ERV3 GFI1 GLI family 1 2 3 REST S1 S2 YY1 HIC 1 2 HIVEP
Corticosteroid_receptor
Protein-coding gene in the species Homo sapiens
factors: Vertebrate TATA binding protein factor, ZF5 POZ domain zinc finger, CTCF and BORIS gene family transcriptional regulators, E2F-myc activator/cell
Proline and serine-rich protein 2
Proline_and_serine-rich_protein_2
Long non-coding RNA transcribed from telomeres
known as 61-29-37 Repeats. Additionally, the chromatin organization factors CTCF (CCCTC-Binding Factor), Cohesin, and Rad21 - which are known to aid in the
Telomeric repeat–containing RNA
Telomeric_repeat–containing_RNA
Non-coding RNA
cases of point mutations in the XIST promoter reveal a correlation between CTCF binding and pre-emptive choices of X chromosome inactivation". Human Molecular
XIST
Protein
TFIID TFIIE 1 2 TFIIF 1 2 TFIIH 1 2 4 2I 3A 3C1 3C2 ATBF1 BCL 6 11A 11B CTCF E4F1 EGR 1 2 3 4 ERV3 GFI1 GLI family 1 2 3 REST S1 S2 YY1 HIC 1 2 HIVEP
FOSB
detected by ChIP-exo. This has allowed, for example, the recognition of more CTCF transcription factor binding sites than previously discovered. Lower sequencing
ChIP-exo
Group of proteins
TFIID TFIIE 1 2 TFIIF 1 2 TFIIH 1 2 4 2I 3A 3C1 3C2 ATBF1 BCL 6 11A 11B CTCF E4F1 EGR 1 2 3 4 ERV3 GFI1 GLI family 1 2 3 REST S1 S2 YY1 HIC 1 2 HIVEP
Octamer_transcription_factor
Proteins that bind DNA
TFIID TFIIE 1 2 TFIIF 1 2 TFIIH 1 2 4 2I 3A 3C1 3C2 ATBF1 BCL 6 11A 11B CTCF E4F1 EGR 1 2 3 4 ERV3 GFI1 GLI family 1 2 3 REST S1 S2 YY1 HIC 1 2 HIVEP
WRKY_transcription_factor
Transcription factor activated by vitamin D
TFIID TFIIE 1 2 TFIIF 1 2 TFIIH 1 2 4 2I 3A 3C1 3C2 ATBF1 BCL 6 11A 11B CTCF E4F1 EGR 1 2 3 4 ERV3 GFI1 GLI family 1 2 3 REST S1 S2 YY1 HIC 1 2 HIVEP
Vitamin_D_receptor
Mammalian protein found in Homo sapiens
TFIID TFIIE 1 2 TFIIF 1 2 TFIIH 1 2 4 2I 3A 3C1 3C2 ATBF1 BCL 6 11A 11B CTCF E4F1 EGR 1 2 3 4 ERV3 GFI1 GLI family 1 2 3 REST S1 S2 YY1 HIC 1 2 HIVEP
ATF4
Protein-coding gene in humans
TFIID TFIIE 1 2 TFIIF 1 2 TFIIH 1 2 4 2I 3A 3C1 3C2 ATBF1 BCL 6 11A 11B CTCF E4F1 EGR 1 2 3 4 ERV3 GFI1 GLI family 1 2 3 REST S1 S2 YY1 HIC 1 2 HIVEP
MYB_(gene)
Vertebrate receptor protein and transcription factor
TFIID TFIIE 1 2 TFIIF 1 2 TFIIH 1 2 4 2I 3A 3C1 3C2 ATBF1 BCL 6 11A 11B CTCF E4F1 EGR 1 2 3 4 ERV3 GFI1 GLI family 1 2 3 REST S1 S2 YY1 HIC 1 2 HIVEP
Aryl_hydrocarbon_receptor
Basic structural unit of DNA packaging in eukaryotes
consistent with nucleosomes being able to "slide" along the DNA in cis. CTCF binding sites act as nucleosome positioning anchors so that, when used to
Nucleosome
Protein-coding gene in the species Homo sapiens
TFIID TFIIE 1 2 TFIIF 1 2 TFIIH 1 2 4 2I 3A 3C1 3C2 ATBF1 BCL 6 11A 11B CTCF E4F1 EGR 1 2 3 4 ERV3 GFI1 GLI family 1 2 3 REST S1 S2 YY1 HIC 1 2 HIVEP
SPI1
specific TF according to literature or domain structure – No motif [127] CTCF ENSG00000102974 C2H2 ZF Known motif – High-throughput in vitro [128] CCDSBAGGKGGCGCB
List of human transcription factors
List_of_human_transcription_factors
Transcription factor and coding gene in humans
TFIID TFIIE 1 2 TFIIF 1 2 TFIIH 1 2 4 2I 3A 3C1 3C2 ATBF1 BCL 6 11A 11B CTCF E4F1 EGR 1 2 3 4 ERV3 GFI1 GLI family 1 2 3 REST S1 S2 YY1 HIC 1 2 HIVEP
STAT1
Protein-coding gene in the species Homo sapiens
TFIID TFIIE 1 2 TFIIF 1 2 TFIIH 1 2 4 2I 3A 3C1 3C2 ATBF1 BCL 6 11A 11B CTCF E4F1 EGR 1 2 3 4 ERV3 GFI1 GLI family 1 2 3 REST S1 S2 YY1 HIC 1 2 HIVEP
EGR1
Protein-coding gene in the species Homo sapiens
in ischemic brain injury, but its mechanism in stroke is still enigmatic. CTCF inhibited miR-383-5p expression via its enrichment in the promoter region
HDAC9
American scholar
elite literature (Doctoral thesis). Michigan State University. doi:10.25335/ctcf-wx92. "Janice A. Radway, Professor Emeritus and Bass Fellow". Duke University
Janice_Radway
Protein found in humans
TFIID TFIIE 1 2 TFIIF 1 2 TFIIH 1 2 4 2I 3A 3C1 3C2 ATBF1 BCL 6 11A 11B CTCF E4F1 EGR 1 2 3 4 ERV3 GFI1 GLI family 1 2 3 REST S1 S2 YY1 HIC 1 2 HIVEP
Transcription_factor_Jun
Protein-coding gene in the species Homo sapiens
TFIID TFIIE 1 2 TFIIF 1 2 TFIIH 1 2 4 2I 3A 3C1 3C2 ATBF1 BCL 6 11A 11B CTCF E4F1 EGR 1 2 3 4 ERV3 GFI1 GLI family 1 2 3 REST S1 S2 YY1 HIC 1 2 HIVEP
DTX2
Protein-coding gene in the species Homo sapiens
TFIID TFIIE 1 2 TFIIF 1 2 TFIIH 1 2 4 2I 3A 3C1 3C2 ATBF1 BCL 6 11A 11B CTCF E4F1 EGR 1 2 3 4 ERV3 GFI1 GLI family 1 2 3 REST S1 S2 YY1 HIC 1 2 HIVEP
NFX1
Protein-coding gene in the species Homo sapiens
TFIID TFIIE 1 2 TFIIF 1 2 TFIIH 1 2 4 2I 3A 3C1 3C2 ATBF1 BCL 6 11A 11B CTCF E4F1 EGR 1 2 3 4 ERV3 GFI1 GLI family 1 2 3 REST S1 S2 YY1 HIC 1 2 HIVEP
SOX3
Protein-coding gene in the species Homo sapiens
TFIID TFIIE 1 2 TFIIF 1 2 TFIIH 1 2 4 2I 3A 3C1 3C2 ATBF1 BCL 6 11A 11B CTCF E4F1 EGR 1 2 3 4 ERV3 GFI1 GLI family 1 2 3 REST S1 S2 YY1 HIC 1 2 HIVEP
Farnesoid_X_receptor
Nuclear receptor protein found in humans
TFIID TFIIE 1 2 TFIIF 1 2 TFIIH 1 2 4 2I 3A 3C1 3C2 ATBF1 BCL 6 11A 11B CTCF E4F1 EGR 1 2 3 4 ERV3 GFI1 GLI family 1 2 3 REST S1 S2 YY1 HIC 1 2 HIVEP
Peroxisome proliferator-activated receptor delta
Peroxisome_proliferator-activated_receptor_delta
Family of transcription factor protein complexes
TFIID TFIIE 1 2 TFIIF 1 2 TFIIH 1 2 4 2I 3A 3C1 3C2 ATBF1 BCL 6 11A 11B CTCF E4F1 EGR 1 2 3 4 ERV3 GFI1 GLI family 1 2 3 REST S1 S2 YY1 HIC 1 2 HIVEP
NF-κB
Protein found in humans
TFIID TFIIE 1 2 TFIIF 1 2 TFIIH 1 2 4 2I 3A 3C1 3C2 ATBF1 BCL 6 11A 11B CTCF E4F1 EGR 1 2 3 4 ERV3 GFI1 GLI family 1 2 3 REST S1 S2 YY1 HIC 1 2 HIVEP
CCAAT/enhancer binding protein zeta
CCAAT/enhancer_binding_protein_zeta
Mammalian protein found in Homo sapiens
S, Baxter EW, et al. (April 2009). "A conserved insulator that recruits CTCF and cohesin exists between the closely related but divergently regulated
Granulocyte-macrophage colony-stimulating factor
Granulocyte-macrophage_colony-stimulating_factor
Paired box transcription factor protein
TFIID TFIIE 1 2 TFIIF 1 2 TFIIH 1 2 4 2I 3A 3C1 3C2 ATBF1 BCL 6 11A 11B CTCF E4F1 EGR 1 2 3 4 ERV3 GFI1 GLI family 1 2 3 REST S1 S2 YY1 HIC 1 2 HIVEP
PAX7
Protein found in humans
TFIID TFIIE 1 2 TFIIF 1 2 TFIIH 1 2 4 2I 3A 3C1 3C2 ATBF1 BCL 6 11A 11B CTCF E4F1 EGR 1 2 3 4 ERV3 GFI1 GLI family 1 2 3 REST S1 S2 YY1 HIC 1 2 HIVEP
OLIG2
Protein family
TFIID TFIIE 1 2 TFIIF 1 2 TFIIH 1 2 4 2I 3A 3C1 3C2 ATBF1 BCL 6 11A 11B CTCF E4F1 EGR 1 2 3 4 ERV3 GFI1 GLI family 1 2 3 REST S1 S2 YY1 HIC 1 2 HIVEP
Mef2
Brown KW, Moorwood K, Moon H, Holmgren C, Mardikar SH, et al. (2007). "A CTCF-binding silencer regulates the imprinted genes AWT1 and WT1-AS and exhibits
WT1-AS
Protein-coding gene in the species Homo sapiens
ORegAnno citations correlate with a “NANP” gene, while transcription factors CTCF and CEBPA are confirmed in the enhancer region for the ZNF337 gene. Both
ZNF337
Protein-coding gene in the species Homo sapiens
TFIID TFIIE 1 2 TFIIF 1 2 TFIIH 1 2 4 2I 3A 3C1 3C2 ATBF1 BCL 6 11A 11B CTCF E4F1 EGR 1 2 3 4 ERV3 GFI1 GLI family 1 2 3 REST S1 S2 YY1 HIC 1 2 HIVEP
NFYB
Protein-coding gene in the species Homo sapiens
TFIID TFIIE 1 2 TFIIF 1 2 TFIIH 1 2 4 2I 3A 3C1 3C2 ATBF1 BCL 6 11A 11B CTCF E4F1 EGR 1 2 3 4 ERV3 GFI1 GLI family 1 2 3 REST S1 S2 YY1 HIC 1 2 HIVEP
Zinc_finger_protein_ZPR1
Family of regulator genes
TFIID TFIIE 1 2 TFIIF 1 2 TFIIH 1 2 4 2I 3A 3C1 3C2 ATBF1 BCL 6 11A 11B CTCF E4F1 EGR 1 2 3 4 ERV3 GFI1 GLI family 1 2 3 REST S1 S2 YY1 HIC 1 2 HIVEP
Myc
Protein-coding gene in the species Homo sapiens
TFIID TFIIE 1 2 TFIIF 1 2 TFIIH 1 2 4 2I 3A 3C1 3C2 ATBF1 BCL 6 11A 11B CTCF E4F1 EGR 1 2 3 4 ERV3 GFI1 GLI family 1 2 3 REST S1 S2 YY1 HIC 1 2 HIVEP
NFE2L3
Protein-coding gene in humans
TFIID TFIIE 1 2 TFIIF 1 2 TFIIH 1 2 4 2I 3A 3C1 3C2 ATBF1 BCL 6 11A 11B CTCF E4F1 EGR 1 2 3 4 ERV3 GFI1 GLI family 1 2 3 REST S1 S2 YY1 HIC 1 2 HIVEP
PAX1
Protein that controls rate of transcription of GH genes
TFIID TFIIE 1 2 TFIIF 1 2 TFIIH 1 2 4 2I 3A 3C1 3C2 ATBF1 BCL 6 11A 11B CTCF E4F1 EGR 1 2 3 4 ERV3 GFI1 GLI family 1 2 3 REST S1 S2 YY1 HIC 1 2 HIVEP
Pituitary-specific positive transcription factor 1
Pituitary-specific_positive_transcription_factor_1
Protein-coding gene in the species Homo sapiens
TFIID TFIIE 1 2 TFIIF 1 2 TFIIH 1 2 4 2I 3A 3C1 3C2 ATBF1 BCL 6 11A 11B CTCF E4F1 EGR 1 2 3 4 ERV3 GFI1 GLI family 1 2 3 REST S1 S2 YY1 HIC 1 2 HIVEP
SOX12
Mammalian protein found in humans
TFIID TFIIE 1 2 TFIIF 1 2 TFIIH 1 2 4 2I 3A 3C1 3C2 ATBF1 BCL 6 11A 11B CTCF E4F1 EGR 1 2 3 4 ERV3 GFI1 GLI family 1 2 3 REST S1 S2 YY1 HIC 1 2 HIVEP
Androgen_receptor
Protein-coding gene in the species Homo sapiens
TFIID TFIIE 1 2 TFIIF 1 2 TFIIH 1 2 4 2I 3A 3C1 3C2 ATBF1 BCL 6 11A 11B CTCF E4F1 EGR 1 2 3 4 ERV3 GFI1 GLI family 1 2 3 REST S1 S2 YY1 HIC 1 2 HIVEP
Factor_in_the_germline_alpha
Protein-coding gene in the species Homo sapiens
TFIID TFIIE 1 2 TFIIF 1 2 TFIIH 1 2 4 2I 3A 3C1 3C2 ATBF1 BCL 6 11A 11B CTCF E4F1 EGR 1 2 3 4 ERV3 GFI1 GLI family 1 2 3 REST S1 S2 YY1 HIC 1 2 HIVEP
FOXG1
Protein-coding gene in the species Homo sapiens
TFIID TFIIE 1 2 TFIIF 1 2 TFIIH 1 2 4 2I 3A 3C1 3C2 ATBF1 BCL 6 11A 11B CTCF E4F1 EGR 1 2 3 4 ERV3 GFI1 GLI family 1 2 3 REST S1 S2 YY1 HIC 1 2 HIVEP
NFKB2
Genes on human chromosome 9
TFIID TFIIE 1 2 TFIIF 1 2 TFIIH 1 2 4 2I 3A 3C1 3C2 ATBF1 BCL 6 11A 11B CTCF E4F1 EGR 1 2 3 4 ERV3 GFI1 GLI family 1 2 3 REST S1 S2 YY1 HIC 1 2 HIVEP
Retinoid_X_receptor
Segment of nucleic acid that affects the expression of associated genes
The loop is stabilized by a dimer of a connector protein (e.g. dimer of CTCF or YY1), with one member of the dimer anchored to its binding motif on the
Regulatory_sequence
Protein-coding gene in the species Homo sapiens
TFIID TFIIE 1 2 TFIIF 1 2 TFIIH 1 2 4 2I 3A 3C1 3C2 ATBF1 BCL 6 11A 11B CTCF E4F1 EGR 1 2 3 4 ERV3 GFI1 GLI family 1 2 3 REST S1 S2 YY1 HIC 1 2 HIVEP
Thyroid_hormone_receptor_beta
Protein-coding gene in the species Homo sapiens
TFIID TFIIE 1 2 TFIIF 1 2 TFIIH 1 2 4 2I 3A 3C1 3C2 ATBF1 BCL 6 11A 11B CTCF E4F1 EGR 1 2 3 4 ERV3 GFI1 GLI family 1 2 3 REST S1 S2 YY1 HIC 1 2 HIVEP
RAR-related orphan receptor alpha
RAR-related_orphan_receptor_alpha
Protein-coding gene in the species Homo sapiens
TFIID TFIIE 1 2 TFIIF 1 2 TFIIH 1 2 4 2I 3A 3C1 3C2 ATBF1 BCL 6 11A 11B CTCF E4F1 EGR 1 2 3 4 ERV3 GFI1 GLI family 1 2 3 REST S1 S2 YY1 HIC 1 2 HIVEP
Retinoid_X_receptor_alpha
Protein found in humans
TFIID TFIIE 1 2 TFIIF 1 2 TFIIH 1 2 4 2I 3A 3C1 3C2 ATBF1 BCL 6 11A 11B CTCF E4F1 EGR 1 2 3 4 ERV3 GFI1 GLI family 1 2 3 REST S1 S2 YY1 HIC 1 2 HIVEP
Msh_homeobox_2
Mammalian protein found in humans
TFIID TFIIE 1 2 TFIIF 1 2 TFIIH 1 2 4 2I 3A 3C1 3C2 ATBF1 BCL 6 11A 11B CTCF E4F1 EGR 1 2 3 4 ERV3 GFI1 GLI family 1 2 3 REST S1 S2 YY1 HIC 1 2 HIVEP
SMAD4
travel, tourism, insurance
CTCF
CTCF
CTCF
CTCF
CTCF
CTCF
CTCF
CTCF
CTCF
travel, tourism, insurance