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Segment of nucleic acid that affects the expression of associated genes
A regulatory sequence is a segment of a nucleic acid molecule which is capable of increasing or decreasing the expression of specific genes within an
Regulatory_sequence
Sequence of DNA that determines traits in an organism
intermediate template for the synthesis of a protein. Genes and their regulatory sequences are mainly responsible for determining the physical traits, or the
Gene
DNA sequence that binds activators to increase the likelihood of gene transcription
strategies have led to a better understanding of the features of regulatory DNA sequences, the prediction, and the design of synthetic enhancers. Building
Enhancer_(genetics)
the insulin transcription start site, called the "insulin regulatory sequence". This sequence is made up of several distinct regions with different biochemical
Insulin_regulatory_sequence
All genetic material of an organism
non-coding genes, other functional regions of the genome such as regulatory sequences (see non-coding DNA), and often a substantial fraction of junk DNA
Genome
Group of open reading frames under the same regulation
important in its function is a regulatory gene, a constantly expressed gene which codes for repressor proteins. The regulatory gene does not need to be in
Operon
Organisation of elements within a gene
functional. This includes the sequence that actually encodes the functional protein or ncRNA, as well as multiple regulatory sequence regions. These regions
Gene_structure
Complete set of nucleic acid sequences for humans
genome might be devoted to regulatory sequences. A value of 8% would correspond to approximately 10,000 bp of regulatory DNA per gene and a value of
Human_genome
DNA that does not code for proteins
piRNA, ribosomal RNA, and regulatory RNAs). Other functional regions of the non-coding DNA fraction include regulatory sequences that control gene expression;
Non-coding_DNA
Region of non-coding DNA that regulates the transcription of neighboring genes
Both of these sequence elements are structural regions of DNA that serve as transcriptional regulators.[citation needed] Cis-regulatory modules are one
Cis-regulatory_element
Protein that increases transcription of a gene or set of genes
"activation domain". Most activators function by binding sequence-specifically to a regulatory DNA site located near a promoter and making protein–protein
Activator_(genetics)
Cats with genetic anomaly that causes extra toes
of its paws. A point mutation in the noncoding region of the ZRS regulatory sequence causes abnormal SHH expression during limb development, causing variable
Polydactyl_cat
Gene involved in controlling expression of other genes
regulator, or regulatory gene is a gene involved in controlling the expression of one or more other genes. Regulatory sequences, which encode regulatory genes
Regulator_gene
Process of copying a segment of DNA into RNA
protein. The regulatory sequence before (upstream from) the coding sequence is called the five prime untranslated regions (5'UTR); the sequence after (downstream
Transcription_(biology)
Portion of gene's sequence which codes for protein
can be controlled by a regulatory sequence found before the open reading frame begins in a strand of DNA. The regulatory sequence will then determine the
Coding_region
RNA processing within a biological cell
produced by transcription often contains both exons (coding sequences) and introns (non-coding sequences); splicing removes the introns and links the exons directly
Post-transcriptional modification
Post-transcriptional_modification
Faculty of mind to store and retrieve data
are not immediately repaired. About 600 regulatory sequences in promoters and about 800 regulatory sequences in enhancers appear to depend on double strand
Memory
Control of DNA to RNA conversion in cells
of activators or repressors. In the absence of other regulatory elements, a promoter's sequence-based affinity for RNA polymerases varies, which results
Transcriptional_regulation
DNA sequence
non-coding sequences are functional elements of the genome other than coding DNA. Some of these functional elements include non-coding genes, regulatory sequences
Conserved_non-coding_sequence
Region of DNA encouraging transcription
conformation of regulatory proteins in a cell, which enable activating transcription factors to recruit RNA polymerase. Given the short sequences of most promoter
Promoter_(genetics)
Chinese fluffy breed of chicken
shown to be a SNP in a regulator of the SHH gene, called the ZPA Regulatory Sequence (ZRS). This causes ectopic SHH expression in the anterior of the
Silkie
DNA sequences with no known biological function
coding regions such as genes for ribosomal RNA and transfer RNA, regulatory sequences, origins of replication, centromeres, telomeres, and scaffold attachment
Junk_DNA
Technique in molecular biology
cellular processes in real-time. Reporter genes are often fused to regulatory sequences of genes of interest, enabling scientists to analyze promoter activity
Reporter_gene
DNA sequence
which has a shorter consensus sequence. The TATA box is considered a non-coding DNA sequence (also known as a cis-regulatory element). It was termed the
TATA_box
Gene or genetic material that has been transferred from one organism to another
promoter, which is a regulatory sequence that will determine where and when the transgene is active, an exon, a protein coding sequence (usually derived from
Transgene
An upstream activating sequence or upstream activation sequence (UAS) is a cis-acting regulatory sequence found in yeast like Saccharomyces cerevisiae
Upstream_activating_sequence
DNA segment
cassette is a distinct component of vector DNA consisting of a gene and regulatory sequence to be expressed by a transfected cell. In each successful transformation
Expression_cassette
gene starts in microbial genomes. Implications for finding sequence motifs in regulatory regions". Nucleic Acids Research. 29 (12): 2607–18. doi:10.1093/nar/29
List of gene prediction software
List_of_gene_prediction_software
DNA response element in some eukaryotes
but distinct elements to bind E-box and tetraplex structures of regulatory sequences of muscle-specific genes". Nucleic Acids Res. 35 (21): 7087–7095
E-box
Most common variant of a genetic sequence across samples
Specific sequence motifs can function as regulatory sequences controlling biosynthesis, or as signal sequences that direct a molecule to a specific site
Consensus_sequence
Development of limbs in vertebrates
enhancer sequences may have contributed to the progressive limb loss in snake evolution. In particular, many studies have focused on the ZPA Regulatory Sequence
Limb_development
Topics referred to by the same term
may refer to: A3 paper, a paper size defined by ISO 216 A3 regulatory sequence, a sequence for the insulin gene Adenosine A3 receptor, a human gene Annexin
A3
transcription initiation without a functional TATA box. It has the consensus sequence YYA+1NWYY in humans. Similarly to the TATA box, the Inr element facilitates
Initiator_element
Biological mechanism
super-enhancer, located downstream the more distal Calpha gene, the 3' regulatory region (3'RR). In some occasions, the 3'RR super-enhancer can itself be
Immunoglobulin class switching
Immunoglobulin_class_switching
Protein found in humans
factors that have been predicted by Genomatix that binds to the regulatory sequence of the CCDC138 gene. CCDC138 has been identified as one of the many
CCDC138
Distinct pattern of nucleotides in molecular biology
binding general transcription factors. Both of these consensus sequences belong to the regulatory promoter. Full gene expression occurs when transcription activator
CAAT_box
Studies of the visible part of a canine
study found a regulatory sequence next to the gene Insulin-like growth factor 1 (IGF1), which, together with the gene and regulatory sequence, "is a major
Dog_anatomy
Topics referred to by the same term
three-dimensional space group number 5 C2 domain, a protein structural domain C2 regulatory sequence for the insulin gene Apolipoprotein C2, a human apolipoprotein In
C2
gene-expression regulatory sequences (promoter and poly-A addition site sequences) also could have originated from stop codons. A conserved sequence, AATAAA,
Split_gene_theory
Polygenic phenotypic characteristic
counts, hair and skin tone. The polymorphisms may be in an OCA2 regulatory sequence, where they may influence the expression of the gene product, which
Eye_color
Malaysian haematologist
between MYB and HBS1L. Thain showed that this interval contains regulatory sequences. She has investigated how QTL regulates the expression of MYB and
Swee_Lay_Thein
State of having more than five digits in ancient fish and tetrapods
of polarizing region activity regulatory sequence) that is located approximately 1 Mb upstream of the coding sequence of Shh." Devonian taxa were polydactylous
Polydactyly_in_stem-tetrapods
Protein-coding gene in the species Homo sapiens
protein encoded by SON gene binds to a specific DNA sequence upstream of the upstream regulatory sequence of the core promoter and second enhancer of human
SON_(gene)
Cellular process of protein synthesis
mRNAs can have different translation rates due to the presence of regulatory sequence elements. This has been shown to be important in a variety of settings
Translation_(biology)
DNA sequence required in bacterial promoters for transcription
The Pribnow box (also known as the Pribnow-Schaller box) is a sequence of TATAAT of six nucleotides (thymine, adenine, thymine, etc.) that is an essential
Pribnow_box
Class of proteins involved in regulation of transcription
domain that binds either to a DNA promoter site or a specific DNA regulatory sequence called an enhancer. Binding of the activator-coactivator complex
Coactivator_(genetics)
Functionless relative of a gene
Pseudogenes are usually identified when genome sequence analysis finds gene-like sequences that lack regulatory sequences or are incapable of producing a functional
Pseudogene
Nucleotide or amino-acid sequence pattern
the "B-form" DNA double helix). Outside of gene exons, there exist regulatory sequence motifs and motifs within the "junk", such as satellite DNA. Some
Sequence_motif
Alteration in the nucleotide sequence of a genome
is in a coding or non-coding region. Mutations in the non-coding regulatory sequences of a gene, such as promoters, enhancers, and silencers, can alter
Mutation
(BRE) is a DNA sequence found in the promoter region of most[clarification needed] genes in eukaryotes and Archaea. The BRE is a cis-regulatory element that
B_recognition_element
Heritable characteristics affecting learning
are not immediately repaired. About 600 regulatory sequences in promoters and about 800 regulatory sequences in enhancers appear to depend on double strand
Epigenetics in learning and memory
Epigenetics_in_learning_and_memory
Field of molecular biology
constructs of candidate cis-regulatory elements is generated, each of these elements is linked to a unique barcode sequence and then cloned into plasmids
Functional_genomics
Belgian bio-engineer and computational biologist
(2005-07-01). "TOUCAN 2: the all-inclusive open source workbench for regulatory sequence analysis". Nucleic Acids Research. 33 (Web Server issue): W393–396
Stein_Aerts
Topics referred to by the same term
amplitude of an optical signal. Attenuator (genetics), a specific regulatory sequence transcribed into RNA. Impact attenuator, used on highways as a crumple
Attenuator
Type of machine learning model
nature. Nucleic acid models have proven useful in detecting regulatory sequences, sequence classification, RNA-RNA interaction prediction, and RNA structure
Large_language_model
Topics referred to by the same term
protein component of proteasome-mediated protein degradation E2 regulatory sequence, for the insulin gene Levuglandin E2, an aldehyde Prostaglandin E2
E2
Protein that exhibits bright green fluorescence when exposed to ultraviolet light
proteins and that is controlled by the same regulatory sequence; that is, the gene's regulatory sequence now controls the production of GFP, in addition
Green_fluorescent_protein
consensus sequence was originally thought to be RGWCGTG, however more recent studies have suggested it to be the similar but more general sequence RGWYV(T)
Downstream_promoter_element
Topics referred to by the same term
reaction, which targets a protein for degradation via a proteasome] E1 regulatory sequence for the insulin gene Estrone, a hormone Pyruvate dehydrogenase (E1)
E1
Transcription is heterocatalytic function of DNA
promoter. Well-characterized regulatory elements include enhancers, silencers, and insulators. These regulatory sequences can be spread over a large genomic
Eukaryotic_transcription
Topics referred to by the same term
A5 and variants may refer to: A5 regulatory sequence in biochemistry A5, the abbreviation for the androgen Androstenediol Annexin A5, a human cellular
A5
a regulatory sequence that showed evidence of hominid adaptation, such as higher nucleotide substitution rates and certain regulatory sequences that
Contribution of epigenetic modifications to evolution
Contribution_of_epigenetic_modifications_to_evolution
Biological cell regulation mechanisms
certain sequences.[citation needed] Three prime untranslated regions (3'-UTRs) of messenger RNAs (mRNAs) often contain regulatory sequences that post-transcriptionally
Regulation_of_gene_expression
Process of determining the nucleic acid sequence
researchers to identify changes in genes and noncoding DNA (including regulatory sequences), associations with diseases and phenotypes, and identify potential
DNA_sequencing
Limbless, scaly, elongate reptile
with DNA mutations in the Zone of Polarizing Activity Regulatory Sequence (ZRS), a regulatory region of the sonic hedgehog gene which is critically required
Snake
Conversion of a gene's sequence into a mature gene product or products
untranslated regions (3′UTRs) of messenger RNAs (mRNAs) often contain regulatory sequences that post-transcriptionally influence gene expression. Such 3′-UTRs
Gene_expression
Medical condition
Primarily, mutations are found in the zone of polarizing activity regulatory sequence, or ZRS, that controls the expression of SHH in developing limbs
Polysyndactyly
RNA family
(nuclear factor of activated T cells) Predicted secondary structure and sequence conservation of NRON Identifiers Symbol NRON Rfam RF00636 Other data RNA
NRON
Biological term
inter-individual differences in DNA methylation are mainly determined by cis-regulatory sequence polymorphisms, probably involving mutations in TFBSs (Transcription
Epigenome
Topics referred to by the same term
protein domain C1-inhibitor, a human serine protease inhibitor C1 regulatory sequence for the insulin gene Apolipoprotein C1, a human lipoprotein Chlorophyll
C1
Ability of an organism to exert itself and remain active for a long period of time
regulated, as in tissues generally, by regulatory DNA sequences, especially enhancers. Enhancers are non-coding sequences in the genome that activate the expression
Endurance
Topics referred to by the same term
Geb Čeb, old name for Čelarevo, Serbia CAAT enhancer binding, a regulatory sequence in DNA Census Enumerators' Books, books used by researchers in social
CEB
Small domesticated bird
larger leg bones. The cause of these changes is a change in the regulatory sequences of DNA that control the expression of the Pitx1 and the Tbx5 genes
Domestic_pigeon
that perform non-coding functions. These represent a new class of regulatory sequences and may have played an important role in the development of specific
HCONDELs
Topics referred to by the same term
G-1, or G One may refer to: G1 phase, in the cellular cycle G1 regulatory sequence for the insulin gene ATC code G01 Gynecological antiinfectives and
G1
Computational analysis of large, complex sets of biological data
determine genes that encode proteins, RNA genes, regulatory sequences, structural motifs, and repetitive sequences. A comparison of genes within a species or
Bioinformatics
Virus or plasmid designed for gene expression in cells
the production of proteins. The vector is engineered to contain regulatory sequences that act as enhancer and promoter regions and lead to efficient transcription
Expression_vector
Hypothesis for alleles
(not necessarily disease-causing) are known to exist in coding and regulatory sequences of genes. According to the CD-CV hypothesis, some of those variants
Common_disease-common_variant
Research consortium investigating functional elements in human and model organism DNA
- a variety of DNA elements, such as promoters, transcriptional regulatory sequences, and regions of chromatin structure and histone modification. It
ENCODE
Area of genome devoid of protein-coding genes
elements, including regulatory sequences, but also large stretches of junk DNA (See Non-coding DNA). One study focused on a regulatory archipelago, a region
Gene_desert
RNA that is read by the ribosome to produce a protein
composing a final complex protein) and their coding sequence is grouped and regulated together in a regulatory region, containing a promoter and an operator
Messenger_RNA
codon and a stop codon. operator A regulatory sequence within an operon, typically located between the promoter sequence and the structural genes of the
Glossary of cellular and molecular biology (M–Z)
Glossary_of_cellular_and_molecular_biology_(M–Z)
Database
from GO. The nucleotide sequences of the promoter and coding regions for Yeast genes were obtained from Regulatory Sequence Analysis Tools (RSAT). All
Yeastract
Process by which a genome changes in structure or size over time
obtained new functions. Given that gene expression is driven by short regulatory sequences, this demonstrates that relatively few mutations are required to
Genome_evolution
Protein that regulates the rate of DNA transcription
may be classified by their (1) mechanism of action, (2) regulatory function, or (3) sequence homology (and hence structural similarity) in their DNA-binding
Transcription_factor
Sex-specific adaptations
traits may involve transcription factors or cofactors rather than regulatory sequences. Sexual dimorphism may also influence differences in parental investment
Sexual_dimorphism
Species of flowering plant
alkaloid gene clusters across fungal endophytes: predicting the co-regulatory sequence motifs and the evolutionary history". Fungal Genetics and Biology
Lolium_arundinaceum
Protein found in humans
nucleotides between the edited nucleoside and this mooring sequence. There is also a regulatory sequence 3′ to the editing site. The active site of ApoBEC-1
Apolipoprotein_B
Regulatory DNA sequences
Distal promoter elements are regulatory DNA sequences that can be many kilobases distant from the gene that they regulate. They can either be enhancers
Distal_promoter
Molecule that carries genetic information
annotations that identify the locations of genes and regulatory elements on each chromosome. Regions of DNA sequence that have the characteristic patterns associated
DNA
Property of nucleic acid strands with respect to their translatability into protein
in which amino acids are assembled to make proteins, as well as regulatory sequences, splicing sites, non-coding introns, and other gene products. For
Sense_(molecular_biology)
these IEG genes. Activation of more than 600 regulatory sequences in promoters and 800 regulatory sequences in enhancers, in many cell types, appears to
TOP2B
Field of study
regulated, as in tissues generally, by regulatory DNA sequences, especially enhancers. Enhancers are non-coding sequences in the genome that activate the expression
Epigenetics of physical exercise
Epigenetics_of_physical_exercise
Gene formed by the combination of two independent genes
non-coding sequence region, it can lead to the misregulation of the expression of a gene now under the control of the cis-regulatory sequence of another
Fusion_gene
Region of DNA in a eukaryotic chromosome
sequence (ACS) is a region of DNA in a eukaryotic chromosome in which histone modifications such as acetylation lead to exposure of the DNA sequence thus
Active_chromatin_sequence
Laboratory technique to multiply a DNA sample for study
fragments that contain complementary sequences. It is used to join DNA pieces containing genes, regulatory sequences, or mutations; the technique enables
Polymerase_chain_reaction
Medical condition
Wilkie, Andrew O. M. (2008-08-15). "A variant in the sonic hedgehog regulatory sequence (ZRS) is associated with triphalangeal thumb and deregulates expression
Familial opposable triphalangeal thumbs duplication
Familial_opposable_triphalangeal_thumbs_duplication
Chromosome that differs from an ordinary autosome in form, size, and behavior
or internal organs. There is a gene in the Y chromosome that has regulatory sequences that control genes that code for maleness, called the SRY gene. This
Sex_chromosome
Protein-coding gene in the species Homo sapiens
Protein FAM46B also known as family with sequence similarity 46 member B is a protein that in humans is encoded by the FAM46B gene. FAM46B contains one
Protein_FAM46B
DNA Sequence
Posttranscriptional Regulatory Element (WPRE) is a DNA sequence that, when transcribed, creates a tertiary structure enhancing expression. The sequence is commonly
WHP Posttranscriptional Response Element
WHP_Posttranscriptional_Response_Element
REGULATORY SEQUENCE
REGULATORY SEQUENCE
Girl/Female
Bengali, Gujarati, Hindu, Indian, Kannada, Malayalam, Marathi, Sanskrit, Telugu
Sequence
Boy/Male
Indian, Sanskrit
Connector; Regulator
Boy/Male
Indian, Sanskrit
Order; Sequence
Surname or Lastname
English
English : from a medieval male personal name (from Latin Hilarius, a derivative of hilaris ‘cheerful’, ‘glad’, from Greek hilaros ‘propitious’, ‘joyful’). The Latin name was chosen by many early Christians to express their joy and hope of salvation, and was borne by several saints, including a 4th-century bishop of Poitiers noted for his vigorous resistance to the Arian heresy, and a 5th-century bishop of Arles. Largely due to veneration of the first of these, the name became popular in France in the forms Hilari and Hilaire, and was brought to England by the Norman conquerors.English : from the much rarer female personal name Eulalie (from Latin Eulalia, from Greek eulalos ‘eloquent’, literally well-speaking, chosen by early Christians as a reference to the gift of tongues), likewise introduced into England by the Normans. A St. Eulalia was crucified at Barcelona in the reign of the Emperor Diocletian and became the patron of that city. In England the name underwent dissimilation of the sequence -l-l- to -l-r- and the unfamiliar initial vowel was also mutilated, so that eventually the name was considered as no more than a feminine form of Hilary (of which the initial aspirate was in any case variable).
Girl/Female
Tamil
Anuloma | அநà¯à®²à¯‹à®®à®¾
Sequence
Anuloma | அநà¯à®²à¯‹à®®à®¾
Boy/Male
Indian, Sikh
Music; In-sequence
REGULATORY SEQUENCE
REGULATORY SEQUENCE
Girl/Female
Indian
Chaste, Pure, Pious, Clean
Girl/Female
Gujarati, Hindu, Indian, Kannada, Malayalam, Marathi, Sanskrit, Sindhi, Tamil, Telugu
Dear One; Beloved
Boy/Male
Hindu
Will, Determination, Resolve
Girl/Female
British, English
Lover of Tristan
Female
French
Feminine form of French Philippe, PHILIPPINE means "lover of horses."
Boy/Male
Australian, Gaelic, Irish
Child of the Old Hero; Small and Ancient; Old Hero
Girl/Female
American, Hindu, Indian
Meeting; Get Together; Eager; Rival
Girl/Female
Hindu, Indian
Sweet Hearted / Kind Hearted
Girl/Female
German, Latin
Firm
Surname or Lastname
English
English : variant spelling of Byas.
REGULATORY SEQUENCE
REGULATORY SEQUENCE
REGULATORY SEQUENCE
REGULATORY SEQUENCE
REGULATORY SEQUENCE
n.
A contrivance for regulating and controlling motion, as: (a) The lever or index in a watch, which controls the effective length of the hairspring, and thus regulates the vibrations of the balance. (b) The governor of a steam engine. (c) A valve for controlling the admission of steam to the steam chest, in a locomotive.
n.
One who, or that which, regulates.
n.
One who, or that which, disposes; a regulator; a director; a bestower.
a.
Pertaining to emulation; connected with rivalry.
n.
All five cards, of a hand, in consecutive order as to value, but not necessarily of the same suit; when of one suit, it is called a sequence flush.
n.
A member of a volunteer committee which, in default of the lawful authority, undertakes to preserve order and prevent crimes; also, sometimes, one of a band organized for the comission of violent crimes.
n.
That which follows as a result; a sequence.
a.
Tending tu refute; refuting.
n.
A melodic phrase or passage successively repeated one tone higher; a rosalia.
n.
A sequence of three playing cards of the same suit. Tierce of ace, king, queen, is called tierce-major.
n.
Simple succession, or the coming after in time, without asserting or implying causative energy; as, the reactions of chemical agents may be conceived as merely invariable sequences.
n.
A form of melody in which a phrase or passage is successively repeated, each time a step or half step higher; a melodic sequence.
a.
Pertaining to, or containing, redargution; refutatory.
n.
A number of things or events standing or succeeding in order, and connected by a like relation; sequence; order; course; a succession of things; as, a continuous series of calamitous events.
n.
Three or more cards of the same suit in immediately consecutive order of value; as, ace, king, and queen; or knave, ten, nine, and eight.
v. t.
One who, or that which, directs another in his conduct or course of lifo; a director; a regulator.
n.
The quality or state of succession in a series; sequence.
n.
A course ending where it began; a circuit; a beat; especially, one freguently or regulary traversed; also, the act of traversing a circuit; as, a watchman's round; the rounds of the postman.
n.
A clock, or other timepiece, used as a standard of correct time. See Astronomical clock (a), under Clock.
n.
A hymn introduced in the Mass on certain festival days, and recited or sung immediately before the gospel, and after the gradual or introit, whence the name.