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ANTICANCER GENE

  • Anticancer gene
  • Type of gene used for anticancer

    Anticancer genes have a special ability to target and kill cancer cells without harming healthy ones. They do this through processes like programmed cell

    Anticancer gene

    Anticancer_gene

  • Tumor suppressor gene
  • Gene that inhibits tumorigenic phenotype

    suppressors include pVHL, APC, CD95, ST5, YPEL3, ST7, and ST14, p16, BRCA2. Anticancer gene Metastasis suppressor Adenomatosis polyposis coli Oncogene Cancer DNA

    Tumor suppressor gene

    Tumor suppressor gene

    Tumor_suppressor_gene

  • Oncogene
  • Gene that has the potential to cause cancer

    intensifying treatment in this poor prognostic group. Anticancer gene Oncogenomics Tumor suppressor gene Oncovirus Genetic predisposition Quantitative trait

    Oncogene

    Oncogene

    Oncogene

  • Dendrimer
  • Highly ordered, branched polymeric molecule

    dendrimers: Enhancing efficacy and mitigating toxicity for effective anticancer drug and gene delivery". Acta Biomaterialia. 43: 14–29. doi:10.1016/j.actbio

    Dendrimer

    Dendrimer

    Dendrimer

  • Phorbol-12-myristate-13-acetate-induced protein 1
  • Protein-coding gene in the species Homo sapiens

    protein 1 is a protein that in humans is encoded by the PMAIP1 gene, and is also known as Noxa. Noxa (Latin for damage) is a pro-apoptotic member

    Phorbol-12-myristate-13-acetate-induced protein 1

    Phorbol-12-myristate-13-acetate-induced protein 1

    Phorbol-12-myristate-13-acetate-induced_protein_1

  • HAMLET (protein complex)
  • HAMLET (Human Alpha-lactalbumin Made LEthal to Tumor cells) is a complex between alpha-lactalbumin and oleic acid that has been shown in cell culture experiments

    HAMLET (protein complex)

    HAMLET_(protein_complex)

  • Antineoplastic
  • Class of drugs used to treat malignant tumors

    Antineoplastic agents, also known as anticancer drugs or antineoplastic drugs, are medications used to treat malignant tumors. These drugs work through

    Antineoplastic

    Antineoplastic

    Antineoplastic

  • Epithelioid sarcoma
  • Medical condition

    Li; Reisman, David (2014). "The silencing of the SWI/SNF subunit and anticancer gene BRM in Rhabdoid tumors". Oncotarget. 5 (10): 3316–32. doi:10.18632/oncotarget

    Epithelioid sarcoma

    Epithelioid sarcoma

    Epithelioid_sarcoma

  • TRAIL
  • Mammalian protein

    both apoptosis and necrosis, which makes them a potential candidate for anticancer drug development. Recent studies show that in cancer cells treated with

    TRAIL

    TRAIL

    TRAIL

  • P53
  • Mammalian protein found in humans

    a tumor suppressor gene. The TP53 gene is the most frequently mutated gene (>50%) in human cancer, indicating that the TP53 gene plays a crucial role

    P53

    P53

    P53

  • PAWR
  • Protein-coding gene in humans

    response-4, is a tumor-suppressor protein coded for in the human by the PAWR gene, that induces apoptosis in cancer cells, but not in normal cells. The tumor

    PAWR

    PAWR

    PAWR

  • BRAF (gene)
  • Protein-coding gene in humans

    BRAF is a human gene that encodes a protein called B-Raf. The gene is also referred to as proto-oncogene B-Raf and v-Raf murine sarcoma viral oncogene

    BRAF (gene)

    BRAF (gene)

    BRAF_(gene)

  • Platinum-based antineoplastic
  • Chemotherapeutic agents used to treat cancer

    Approved platinum-based anticancer drugs cisplatin carboplatin oxaliplatin nedaplatin Dicycloplatin Platinum-based anticancer drugs in trials triplatin

    Platinum-based antineoplastic

    Platinum-based_antineoplastic

  • Chemotherapy
  • Treatment of cancer using drugs that inhibit cell division or kill cells

    hyperthermia, it was important to show that chemoresistance against several anticancer drugs (e.g. mitomycin C, anthracyclines, BCNU, melphalan) including CDDP

    Chemotherapy

    Chemotherapy

    Chemotherapy

  • KRAS
  • Protein-coding gene in humans

    Forrester K, Jordano J, et al. (1987). "The c-K-ras gene and human cancer (review)". Anticancer Research. 7 (4A): 639–652. PMID 3310850. Yamamoto F,

    KRAS

    KRAS

    KRAS

  • Temozolomide
  • Cancer medication

    Temozolomide, sold under the brand name Temodar among others, is an anticancer medication used to treat brain tumors such as glioblastoma and anaplastic

    Temozolomide

    Temozolomide

    Temozolomide

  • Trophoblastic neoplasm
  • Medical condition

    strategy for metastatic gestational trophoblastic disease: Engineered anticancer gene-expressing stem cells to selectively target choriocarcinoma". Oncology

    Trophoblastic neoplasm

    Trophoblastic neoplasm

    Trophoblastic_neoplasm

  • Topoisomerase inhibitor
  • Compounds that inhibit the activity of DNA topoisomerases

    Aoki D (2012). "Association of epigenetic inactivation of the WRN gene with anticancer drug sensitivity in cervical cancer cells". Oncol. Rep. 28 (4): 1146–52

    Topoisomerase inhibitor

    Topoisomerase_inhibitor

  • Noscapine
  • Chemical compound

    Larson TR, et al. (June 2012). "A Papaver somniferum 10-gene cluster for synthesis of the anticancer alkaloid noscapine". Science. 336 (6089). New York, N

    Noscapine

    Noscapine

    Noscapine

  • Lactoferrin
  • Mammalian protein found in Homo sapiens

    plasma membrane of C. albicans inducing an apoptotic-like process. The anticancer activity of bovine lactoferrin (bLF) has been demonstrated in experimental

    Lactoferrin

    Lactoferrin

    Lactoferrin

  • CYP2B6
  • Protein-coding gene in humans

    Cytochrome P450 2B6 is an enzyme that in humans is encoded by the CYP2B6 gene. CYP2B6 is a member of the cytochrome P450 group of enzymes. Along with CYP2A6

    CYP2B6

    CYP2B6

    CYP2B6

  • Histone deacetylase inhibitor
  • Compounds that inhibit histone deacetylases

    addition to increased expression of BDNF. Pan-HDAC inhibitors have shown anticancer potential in several in in vitro and in vivo studies, focused on Pancreatic

    Histone deacetylase inhibitor

    Histone_deacetylase_inhibitor

  • Telomerase reverse transcriptase
  • Catalytic subunit of the enzyme telomerase

    promoter to restrict induction of apoptosis to tumors in vitro and in vivo". Anticancer Research. 21 (3B): 1937–43. PMID 11497281. Song JS, Kim HP, Yoon WS, Lee

    Telomerase reverse transcriptase

    Telomerase reverse transcriptase

    Telomerase_reverse_transcriptase

  • CYP3A4
  • Enzyme that metabolizes substances by oxidation

    encoded by the CYP3A4 gene. This gene is part of a cluster of cytochrome P450 genes on chromosome 7q22.1. Previously another CYP3A gene, CYP3A3, was thought

    CYP3A4

    CYP3A4

    CYP3A4

  • Human leukocyte antigen
  • Genes on human chromosome 6

    The human leukocyte antigen (HLA) system is a complex of genes on chromosome 6 in humans that encode cell-surface proteins responsible for regulation

    Human leukocyte antigen

    Human leukocyte antigen

    Human_leukocyte_antigen

  • Beta-2 adrenergic receptor
  • Mammalian protein found in humans

    beta-2-adrenergic receptor locus on chromosome 5 in human colorectal carcinomas". Anticancer Research. 11 (6): 2047–50. PMID 1663718. Bouvier M, Guilbault N, Bonin

    Beta-2 adrenergic receptor

    Beta-2 adrenergic receptor

    Beta-2_adrenergic_receptor

  • Stefan Grimm
  • German-British biologist and toxicologist

    with the development of cancer. He also revealed a new class of genes – anticancer genes – which could specifically target human cancers. Grimm's research

    Stefan Grimm

    Stefan_Grimm

  • SCEL (gene)
  • Protein-coding gene in the species Homo sapiens

    Sciellin (SCEL) as a candidate gene in esophageal squamous cell carcinoma". Anticancer Res. 24 (3a): 1417–9. PMID 15274303. Champliaud MF, Viel A, Baden HP (2003)

    SCEL (gene)

    SCEL (gene)

    SCEL_(gene)

  • Antimicrobial peptides
  • Class of peptides that have antimicrobial activity

    "Surrounding cells affect the gene expression pattern of human beta-defensins in squamous cell carcinoma in vitro". Anticancer Research. 34 (11): 6443–6449

    Antimicrobial peptides

    Antimicrobial peptides

    Antimicrobial_peptides

  • PD-L1
  • Mammalian protein found in humans

    cells thereby compromising T cell's disease ameliorating activity e.g., anticancer immune reactions. Resting human cholangiocytes express PD-L1 mRNA, but

    PD-L1

    PD-L1

    PD-L1

  • RANKL
  • Mammalian protein found in Homo sapiens

    differentiation factor (ODF), is a protein that in humans is encoded by the TNFSF11 gene. RANKL is known as a type II membrane protein and is a member of the tumor

    RANKL

    RANKL

    RANKL

  • Transcription factor Jun
  • Mammalian protein found in Homo sapiens

    can prevent silencing of the gene p16INK4a.[citation needed] Tylophorine is a type of plant-derived alkaloid with anticancer activity by inducing cell cycle

    Transcription factor Jun

    Transcription factor Jun

    Transcription_factor_Jun

  • Hemocyanin
  • Proteins that transport oxygen throughout the bodies of some invertebrate animals

    "Keyhole limpet hemocyanin, a novel immune stimulant with promising anticancer activity in Barrett's esophageal adenocarcinoma". American Journal of

    Hemocyanin

    Hemocyanin

    Hemocyanin

  • Growth curve (biology)
  • Empirical model of the evolution of a population or biomass over time

    to the toxic effects that conventional anticancer drugs have on the cancer cells. Many conventional anticancer drugs (for example, 5-Fluorouracil) interfere

    Growth curve (biology)

    Growth curve (biology)

    Growth_curve_(biology)

  • Sirtuin 2
  • Protein-coding gene in the species Homo sapiens

    instability during mitosis. SIRT2-specific inhibitors exhibits broad anticancer activity. SIRT2 has been shown to interact with: α-tubulin, TUG, β-catenin

    Sirtuin 2

    Sirtuin 2

    Sirtuin_2

  • Alpha-fetoprotein
  • Fetal analogue of serum albumin

    fetal protein) is a protein that in humans is encoded by the AFP gene. The AFP gene is located on the q arm of chromosome 4 (4q13.3). Maternal AFP serum

    Alpha-fetoprotein

    Alpha-fetoprotein

    Alpha-fetoprotein

  • P-glycoprotein
  • Protein found in humans

    of resistance to anticancer drugs. This protein also functions as a transporter in the blood–brain barrier. Mutations in this gene are associated with

    P-glycoprotein

    P-glycoprotein

    P-glycoprotein

  • TST (gene)
  • Protein-coding gene in the species Homo sapiens

    sulfurtransferase is an enzyme that in humans is encoded by the TST gene. The product of this gene is a mitochondrial matrix enzyme that is encoded by the nucleus

    TST (gene)

    TST (gene)

    TST_(gene)

  • Cancer treatment
  • Medical intervention

    permanent problem. Chemotherapy is the treatment of cancer with drugs ("anticancer drugs") that can destroy cancer cells. Chemotherapy can be given in a

    Cancer treatment

    Cancer treatment

    Cancer_treatment

  • Stephen Neidle
  • British X-ray crystallographer, chemist and drug designer

    H.; Neidle, Stephen (2011). "Targeting G-quadruplexes in gene promoters: A novel anticancer strategy?". Nature Reviews Drug Discovery. 10 (4): 261–275

    Stephen Neidle

    Stephen_Neidle

  • Hemojuvelin
  • "Potential prognostic value of repulsive guidance molecules in breast cancer". Anticancer Research. 31 (5): 1703–1711. PMID 21617229. Kuninger D, Kuns-Hashimoto

    Hemojuvelin

    Hemojuvelin

    Hemojuvelin

  • Reverse engineering
  • Process of extracting design information from anything artificial

    engineering of gene networks range from understanding mechanisms of plant physiology to the highlighting of new targets for anticancer therapy. Reverse

    Reverse engineering

    Reverse engineering

    Reverse_engineering

  • IFNB1
  • Protein-coding gene in the species Homo sapiens

    humans is encoded by the IFNB1 gene. The natural and recombinant protein forms have antiviral, antibacterial, and anticancer properties. Interferon beta

    IFNB1

    IFNB1

    IFNB1

  • Doxorubicin
  • Chemotherapy medication

    Farmitalia Research Laboratories, began an organized effort to find anticancer compounds from soil-based microbes. A soil sample was isolated from the

    Doxorubicin

    Doxorubicin

    Doxorubicin

  • Fibroblast growth factor receptor 1
  • Protein found in humans

    The FGFR1 gene, similar to the FGFR2-4 genes are commonly activated in human cancers as a result of their duplication, fusion with other genes, and point

    Fibroblast growth factor receptor 1

    Fibroblast growth factor receptor 1

    Fibroblast_growth_factor_receptor_1

  • Survivin
  • Mammalian protein

    and anticancer drugs". Cancer Research. 58 (23): 5315–5320. PMID 9850056. Ambrosini G, Adida C, Altieri DC (August 1997). "A novel anti-apoptosis gene, survivin

    Survivin

    Survivin

    Survivin

  • Cyclin D1
  • Protein found in humans

    that in humans is encoded by the CCND1 gene. The CCND1 gene encodes the cyclin D1 protein. The human CCND1 gene is located on the long arm of chromosome

    Cyclin D1

    Cyclin D1

    Cyclin_D1

  • Celecoxib
  • Nonsteroidal anti-inflammatory medication

    adenomatous polyposis, while also being investigated for broader psychiatric, anticancer, and chemopreventive applications. Celecoxib was patented in 1993 and

    Celecoxib

    Celecoxib

    Celecoxib

  • CD276
  • Protein found in humans

    1038/s41467-023-41631-w. PMC 10517151. PMID 37739951. "Servier Pays MacroGenics $20M for Option to Anticancer Antibody - GEN". GEN. December 2011. Kontos F, Michelakos

    CD276

    CD276

    CD276

  • USF1
  • Protein-coding gene in the species Homo sapiens

    is a protein that in humans is encoded by the USF1 gene. The upstream stimulatory factor (USF) gene encodes a transcription factor USF that belongs to

    USF1

    USF1

    USF1

  • Cecropin
  • Protein family

    belongs to this family.[citation needed] A derivative of Cecropin B is an anticancer polypeptide(L). Structure consists of mainly alpha helixes, determined

    Cecropin

    Cecropin

    Cecropin

  • CpG site
  • Region of often-methylated DNA with a cytosine followed by a guanine

    Kaina B (2009). "FEN1 is overexpressed in testis, lung and brain tumors". Anticancer Res. 29 (7): 2453–9. PMID 19596913. Kastan MB (2008). "DNA damage responses:

    CpG site

    CpG site

    CpG_site

  • CDKN1B
  • Protein-coding gene in humans

    (p27Kip1) is an enzyme inhibitor that in humans is encoded by the CDKN1B gene. It encodes a protein which belongs to the Cip/Kip family of cyclin dependent

    CDKN1B

    CDKN1B

    CDKN1B

  • MEN1
  • Protein

    molecular and histopathological features than those without MEN1 gene alterations. Anticancer drugs that exert their pharmacological effect by interfering

    MEN1

    MEN1

    MEN1

  • Penicillium roqueforti
  • Species of fungus

    blue cheese. The andrastins inhibit proteins involved in the efflux of anticancer drugs from multidrug-resistant cancer cells, indicating potential value

    Penicillium roqueforti

    Penicillium roqueforti

    Penicillium_roqueforti

  • PDGFRB
  • Protein-coding gene in humans

    encoded by the PDGFRB gene. Mutations in PDGFRB are mainly associated with the clonal eosinophilia class of malignancies. The PDGFRB gene is located on human

    PDGFRB

    PDGFRB

    PDGFRB

  • Tumor necrosis factor
  • Immune system messenger protein which induces inflammation

    isolated from Coley's bacterial toxins as the substance responsible for the anticancer effect. In particular, endotoxin could cause tumor regression when injected

    Tumor necrosis factor

    Tumor necrosis factor

    Tumor_necrosis_factor

  • Apoptosis regulator BAX
  • Mammalian protein found in Homo sapiens

    Drugs that activate BAX, such as ABT-737, a BH3 mimetic, hold promise as anticancer treatments by inducing apoptosis in cancer cells. For instance, binding

    Apoptosis regulator BAX

    Apoptosis regulator BAX

    Apoptosis_regulator_BAX

  • Melanoma
  • Skin cancer originating in melanocytes

    malignant melanoma: facts about sunbeds and sunscreen". Expert Review of Anticancer Therapy. 5 (5): 821–833. doi:10.1586/14737140.5.5.821. PMID 16221052.

    Melanoma

    Melanoma

    Melanoma

  • PDF (gene)
  • Protein-coding gene in the species Homo sapiens

    new anticancer target of actinonin-based antibiotics". J Clin Invest. 114 (8): 1107–16. doi:10.1172/JCI22269. PMC 522256. PMID 15489958. "Entrez Gene: PDF

    PDF (gene)

    PDF (gene)

    PDF_(gene)

  • Interleukin 24
  • Protein-coding gene in the species Homo sapiens

    et al. (2014). "MDA-7/IL-24: Multifunctional Cancer Killing Cytokine". Anticancer Genes. Advances in Experimental Medicine and Biology. Vol. 818. pp. 127–53

    Interleukin 24

    Interleukin 24

    Interleukin_24

  • Interleukin 15
  • Cytokine with structural similarity to Interleukin-2

    Interleukin-15 (IL-15) is a protein that in humans is encoded by the IL15 gene. IL-15 is an inflammatory cytokine with structural similarity to Interleukin-2

    Interleukin 15

    Interleukin 15

    Interleukin_15

  • SLC22A13
  • Protein-coding gene in the species Homo sapiens

    Alzahrani AJ, Al-Ali A, Sanders TA, Aboagye EO, Grimm S (2015). "The anticancer gene ORCTL3 targets stearoyl-CoA desaturase-1 for tumour-specific apoptosis"

    SLC22A13

    SLC22A13

    SLC22A13

  • Fibroblast activation protein, alpha
  • Enzyme in humans

    prolyl endopeptidase FAP is an enzyme that in humans is encoded by the FAP gene. Prolyl endopeptidase FAP is a 170 kDa membrane-bound gelatinase. It was

    Fibroblast activation protein, alpha

    Fibroblast activation protein, alpha

    Fibroblast_activation_protein,_alpha

  • Bcl-2
  • Protein found in humans

    Bcl-2, encoded in humans by the BCL2 gene, is the founding member of the Bcl-2 family of regulator proteins. BCL2 blocks programmed cell death (apoptosis)

    Bcl-2

    Bcl-2

    Bcl-2

  • DNA repair
  • Cellular mechanism

    SR (September 2005). "Rapid and reversible induction of the longevity, anticancer and genomic effects of caloric restriction". Mechanisms of Ageing and

    DNA repair

    DNA repair

    DNA_repair

  • DPAGT1
  • Protein-coding gene in the species Homo sapiens

    that in humans is encoded by the DPAGT1 gene. Mutations in DPAGT1 cause myasthenia. The protein encoded by this gene is an enzyme that catalyzes the first

    DPAGT1

    DPAGT1

    DPAGT1

  • Topoisomerase
  • Class of enzymes

    1998). "Clinical applications of anticancer drugs targeted to topoisomerase II". Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression. 1400

    Topoisomerase

    Topoisomerase

  • Progeria
  • Genetic disorder that causes early aging

    is a type of progeroid syndrome. A single gene mutation is responsible for causing progeria. The affected gene, known as lamin A (LMNA), makes a protein

    Progeria

    Progeria

    Progeria

  • DCAF15
  • Protein-coding gene in the species Homo sapiens

    Capota E, Kim J, Ting TC, Xie Y, Williams NS, Nijhawan D (April 2017). "Anticancer sulfonamides target splicing by inducing RBM39 degradation via recruitment

    DCAF15

    DCAF15

    DCAF15

  • Salinomycin
  • Chemical compound

    coccidiostat ionophore therapeutic drug. It is widely researched for its anticancer stem cell properties. Salinomycin is also known to isomerise in solution

    Salinomycin

    Salinomycin

    Salinomycin

  • Epidermal growth factor receptor
  • Transmembrane protein

    The identification of EGFR as an oncogene has led to the development of anticancer therapeutics directed against EGFR (called "EGFR inhibitors", EGFRi),

    Epidermal growth factor receptor

    Epidermal growth factor receptor

    Epidermal_growth_factor_receptor

  • Ras GTPase
  • GTP-binding proteins functioning on cell-cycle regulation

    Agrawal AG, Somani RR (June 2009). "Farnesyltransferase inhibitor as anticancer agent". Mini Reviews in Medicinal Chemistry. 9 (6): 638–52. doi:10

    Ras GTPase

    Ras GTPase

    Ras_GTPase

  • Interleukin 2
  • Mammalian protein found in humans

    of IL-2 in the tumor has been shown to be clinically more effective in anticancer therapy than systemic IL-2 therapy, over a broad range of doses, without

    Interleukin 2

    Interleukin 2

    Interleukin_2

  • Hedgehog signaling pathway
  • Embryonic signaling pathway for proper cell differentiation

    suppress hedgehog signaling pathway and pancreatic cancer proliferation". Anticancer Research. 27 (6A): 3743–3747. PMID 17970037. Hunt R, Bragina O, Drews

    Hedgehog signaling pathway

    Hedgehog_signaling_pathway

  • Cathelicidin antimicrobial peptide
  • Group of antimicrobial peptides in vertebrates

    peptide (CAMP) is an antimicrobial peptide encoded in the human by the CAMP gene. The active form is LL-37, a 37 amino acid peptide having sequence

    Cathelicidin antimicrobial peptide

    Cathelicidin antimicrobial peptide

    Cathelicidin_antimicrobial_peptide

  • Fatty acid synthase
  • Class of enzymes

    Fatty acid synthase (FAS) is an enzyme that in humans is encoded by the FASN gene. Fatty acid synthase is a multi-enzyme protein that catalyzes fatty acid

    Fatty acid synthase

    Fatty acid synthase

    Fatty_acid_synthase

  • DNA
  • Molecule that carries genetic information

    Gradillas A, de Pascual-Teresa B, Ramos A (November 2001). "Intercalators as anticancer drugs". Current Pharmaceutical Design. 7 (17): 1745–80. doi:10.2174/1381612013397113

    DNA

    DNA

    DNA

  • Heat shock protein
  • Family of proteins

    Hence small molecule inhibitors of HSPs, especially Hsp90 show promise as anticancer agents. The potent Hsp90 inhibitor 17-AAG was in clinical trials for the

    Heat shock protein

    Heat_shock_protein

  • NPM1
  • Protein-coding gene in humans

    translocated to the nucleoplasm in case of serum starvation or treatment with anticancer drugs. The protein was identified as a phosphoprotein. However, later

    NPM1

    NPM1

    NPM1

  • Ameloblastin
  • Protein-coding gene in the species Homo sapiens

    RS (August 2009). "Mutation of ameloblastin gene in calcifying epithelial odontogenic tumor". Anticancer Research. 29 (8): 3065–3067. PMID 19661317. Tamburstuen

    Ameloblastin

    Ameloblastin

    Ameloblastin

  • Tumor marker
  • Proxy markers for certain cancers

    "Tumor type M2 pyruvate kinase expression in advanced breast cancer". Anticancer Research. 20 (6D): 5077–5082. PMID 11326672. INIST 1059012. Benesch, Carina;

    Tumor marker

    Tumor_marker

  • RPTOR
  • Protein-coding gene in humans

    RPTOR gene. Two mRNAs from the gene have been identified that encode proteins of 1335 (isoform 1) and 1177 (isoform 2) amino acids long. The human gene is

    RPTOR

    RPTOR

    RPTOR

  • Bacillus subtilis
  • Catalase-positive bacterium

    Chemioterapia. 5 (6): 404–07. PMID 3100070. Shylakhovenko VA (June 2003). "Anticancer and Immunostimulatory effects of Nucleoprotein Fraction of 'Bacillus subtilis'"

    Bacillus subtilis

    Bacillus subtilis

    Bacillus_subtilis

  • Sodium/glucose cotransporter 1
  • Mammalian protein found in Homo sapiens

    Pathways for Tumor Cell Growth and Proliferation". Medicinal Chemistry of Anticancer Drugs. Elsevier. pp. 251–305. doi:10.1016/b978-0-444-52824-7.00009-3.

    Sodium/glucose cotransporter 1

    Sodium/glucose cotransporter 1

    Sodium/glucose_cotransporter_1

  • GeneRIF
  • A GeneRIF or Gene Reference Into Function is a short (255 characters or fewer) statement about the function of a gene. GeneRIFs provide a simple mechanism

    GeneRIF

    GeneRIF

  • Therapeutic gene modulation
  • Process of modifying a gene

    differs from gene therapy in that gene modulation seeks to alter the expression of an endogenous gene (perhaps through the introduction of a gene encoding

    Therapeutic gene modulation

    Therapeutic_gene_modulation

  • ERBB3
  • Protein found in humans

    "Expression of c-erbB family gene products in adenoid cystic carcinoma of salivary glands: an immunohistochemical study". Anticancer Research. 15 (6B): 2623–2626

    ERBB3

    ERBB3

    ERBB3

  • Auger therapy
  • Medical intervention

    disrupted the herpes-specific gene in several transformed cell cultures.[citation needed] The group of metal-based anticancer drugs originated with cisplatin

    Auger therapy

    Auger_therapy

  • Dihydrofolate reductase
  • Mammalian protein found in humans

    one-carbon transfer chemistry. In humans, the DHFR enzyme is encoded by the DHFR gene. It is found in the q14.1 region of chromosome 5. There are two structural

    Dihydrofolate reductase

    Dihydrofolate reductase

    Dihydrofolate_reductase

  • TACSTD2
  • Protein-coding gene in the species Homo sapiens

    human gene that encodes tumor-associated calcium signal transducer 2 (Trop-2, or epithelial glycoprotein-1 antigen (EGP-1)) is a . This intronless gene is

    TACSTD2

    TACSTD2

    TACSTD2

  • MACC1, MET transcriptional regulator
  • Protein-coding gene in the species Homo sapiens

    (July 2010). "MACC1 as a marker for advanced colorectal carcinoma". Anticancer Research. 30 (7): 2689–92. PMID 20682999. Shirahata A, Sakata M, Kitamura

    MACC1, MET transcriptional regulator

    MACC1, MET transcriptional regulator

    MACC1,_MET_transcriptional_regulator

  • Warburg effect (oncology)
  • Form of metabolism in tumors

    have been developed which inhibit glycolysis and so have potential as anticancer agents, including SB-204990, 2-deoxy-D-glucose (2DG), 3-bromopyruvate

    Warburg effect (oncology)

    Warburg_effect_(oncology)

  • Emerging technologies
  • Technology still to be fully developed

    "CRISPR/Cas9 technology: towards a new generation of improved CAR-T cells for anticancer therapies". Briefings in Functional Genomics. 19 (3): 191–200. doi:10

    Emerging technologies

    Emerging_technologies

  • Peptide
  • Short chains of 2–50 amino acids

    invertebrate peptides, amphibian/skin peptides, venom peptides, cancer/anticancer peptides, vaccine peptides, immune/inflammatory peptides, brain peptides

    Peptide

    Peptide

    Peptide

  • Synthetic lethality
  • Cell death resulting from a deficiency of or interaction between in two or more genes

    (October 2012). "Association of epigenetic inactivation of the WRN gene with anticancer drug sensitivity in cervical cancer cells". Oncology Reports. 28

    Synthetic lethality

    Synthetic_lethality

  • ABC transporter
  • Gene family

    transport proteins are overexpressed in cancer cells, they can export anticancer drugs and render tumors resistant. ABC transporters utilize the energy

    ABC transporter

    ABC transporter

    ABC_transporter

  • Capecitabine
  • Chemical compound

    Capecitabine, sold under the brand name Xeloda among others, is an anticancer medication used to treat breast cancer, gastric cancer and colorectal cancer

    Capecitabine

    Capecitabine

    Capecitabine

  • Gastrin-releasing peptide
  • is a neuropeptide, a regulatory molecule encoded in the human by the GRP gene. GRP has been implicated in a number of physiological and pathophysiological

    Gastrin-releasing peptide

    Gastrin-releasing peptide

    Gastrin-releasing_peptide

  • Interleukin-1 receptor antagonist
  • Protein and coding gene in humans

    Lichtenegger W (2003). "Polymorphism of IL-1 receptor antagonist gene: role in cancer". Anticancer Research. 22 (6A): 3421–3424. PMID 12530098. Kamangar F, Cheng

    Interleukin-1 receptor antagonist

    Interleukin-1 receptor antagonist

    Interleukin-1_receptor_antagonist

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ANTICANCER GENE

  • Genevra
  • Girl/Female

    Australian, French, Italian

    Genevra

    Italian Form of Genevieve; White Wave; Of the Race of Women; Fair and Yielding; Juniper Tree

    Genevra

  • Leeds
  • Surname or Lastname

    English

    Leeds

    English : habitational name from the city in West Yorkshire, or the place in Kent. The former is of British origin, appearing in Bede in the form Loidis ‘People of the Lāt’, (Lāt being an earlier name of the river Aire, meaning ‘the violent one’). Loidis was originally a district name, but was subsequently restricted to the city. The Kentish place name may be from an Old English stream name hl̄de ‘loud, rushing stream’.Daniel Leeds (1652–1720) was born in England, probably in Nottinghamshire, and emigrated to America with his father, Thomas, some time in the third quarter of the 17th century. The family settled in Shrewsbury, NJ, in 1677. Daniel made almanacs and was surveyor general of the Province of West Jersey in 1682. He was married four times and had numerous children.

    Leeds

  • GENEVRA
  • Female

    Italian

    GENEVRA

    Variant spelling of Italian Ginevra, probably GENEVRA means "race of women."

    GENEVRA

  • Mifflin
  • Surname or Lastname

    English

    Mifflin

    English : unexplained.John Mifflin (born 1640) came to Delaware from Warminster, Wiltshire, England, in the 1670s. He is probably the same person as the John Mifflin, a Quaker, who built his home, ‘Fountain Green’, in Fairmont Park, Philadelphia, in 1679. His fourth-generation descendant Thomas Mifflin (1744–1800) was a member of the Continental Congress, a revolutionary soldier, and governor of PA.

    Mifflin

  • Matthew
  • Surname or Lastname

    English and Scottish

    Matthew

    English and Scottish : from the Middle English personal name Ma(t)thew, vernacular form of the Greek New Testament name Matthias, Matthaios, which is ultimately from the Hebrew personal name Matityahu ‘gift of God’. This was taken into Latin as Mat(t)hias and Matthaeus respectively, the former being used for the twelfth apostle (who replaced Judas Iscariot) and the latter for the author of the first Gospel. In many European languages this distinction is reflected in different surname forms. The commonest vernacular forms of the personal name, including English Matthew, Old French Matheu, Spanish Mateo, Italian Matteo, Portuguese Mateus, Catalan and Occitan Mateu are generally derived from the form Matthaeus. The American surname Matthew has also absorbed European cognates from other languages, including Greek Mathias and Mattheos.It is found as a personal name among Christians in India, and in the U.S. is used as a family name among families from southern India.

    Matthew

  • Maudlin
  • Surname or Lastname

    English

    Maudlin

    English : from the Middle English vernacular form, Maudeleyn, of the New Testament Greek personal name Magdalēnē. This is a byname, meaning ‘woman from Magdala’ (a village on the Sea of Galilee, deriving its name from Hebrew migdal ‘tower’), denoting the woman cured of evil spirits by Jesus (Luke 8:2), who later became a faithful follower. In Christian folk belief she was generally identified with the repentant sinner who washed Christ’s feet with her tears in Luke 7; hence the name came to be used as a byname for a prostitute, also a tearful woman. The popularity of the personal name increased with the supposed discovery of her relics in the 13th century.

    Maudlin

  • Luce
  • Surname or Lastname

    English (Gloucestershire and South Wales)

    Luce

    English (Gloucestershire and South Wales) : most probably from the Norman personal name Luce (a vernacular form of Latin Lucia or Lucius). This is generally a female name, although male bearers are found in France. It was borne by a young Sicilian maiden and an aged Roman widow, both of whom were martyred under Diocletian and are venerated as saints.English (Gloucestershire and South Wales) : Alternatively, the surname may be a variant of Lewis.English (Gloucestershire and South Wales) : American bearers of this surname are descended from Henry Luce (1640–c.1688), who came to Scituate, MA, from south Wales in or before 1666, and moved to Martha’s Vineyard, MA, in about 1670. He had many prominent descendants.

    Luce

  • GENEVIEVE
  • Female

    English

    GENEVIEVE

     English form of French Geneviève, probably GENEVIEVE means "race of women."

    GENEVIEVE

  • GENERYS
  • Female

    Welsh

    GENERYS

    Medieval Welsh name, probably GENERYS means "white lady." 

    GENERYS

  • GENEVA
  • Female

    English

    GENEVA

    Pet form of French Geneviève, probably GENEVA means "race of women."

    GENEVA

  • GENETTE
  • Female

    English

    GENETTE

    English variant spelling of French Jeanette, GENETTE means "God is gracious."

    GENETTE

  • Logsdon
  • Surname or Lastname

    English (Bedfordshire)

    Logsdon

    English (Bedfordshire) : habitational name from an unidentified place. In Tudor records, the surname is generally spelled Logsden or Loggesden. It may be a variant of Loxton, name of a place in Somerset, or possibly an irregularly altered form of Roxton, name of a place in Bedfordshire (see Ruxton).A William Logsden is recorded in Somerset Co., MD, tax rolls in the late 17th century.

    Logsdon

  • Generosa
  • Girl/Female

    Australian, Spanish

    Generosa

    Generous

    Generosa

  • Lakin
  • Surname or Lastname

    Americanized spelling of Jewish Leykin (from Belarus), a metronymic from Leyke, a pet form of the Yiddish female personal name Leye, from the Hebrew female personal name Lea, from which English Leah is derived (see Genesis 29

    Lakin

    Americanized spelling of Jewish Leykin (from Belarus), a metronymic from Leyke, a pet form of the Yiddish female personal name Leye, from the Hebrew female personal name Lea, from which English Leah is derived (see Genesis 29 : 16) + the Slavic possessive suffix -in.English : from a medieval personal name, a diminutive of Lawrence. Compare Law 1 and Larkin.

    Lakin

  • Marr
  • Surname or Lastname

    Scottish

    Marr

    Scottish : habitational name from Mar in Aberdeenshire, the etymology of which is uncertain, possibly Old Norse marr, a rare word generally denoting the sea, but perhaps also a marsh or fen, as reflected in modern dialect forms.English : habitational name from Marr in West Yorkshire, whose name is likewise of uncertain origin; possibly the same as 1.German : from the Germanic personal name Marro.

    Marr

  • Generosb
  • Boy/Male

    Spanish

    Generosb

    Generous.

    Generosb

  • GENEVIÈVE
  • Female

    French

    GENEVIÈVE

    French form of Celtic Genovefa, probably GENEVIÈVE means "race of women."

    GENEVIÈVE

  • GENESIS
  • Female

    English

    GENESIS

    (Γένεσις) English name of Greek origin, derived from the word genesis, GENESIS means "creation, generation, origin, source," from gignesthai "to be born," which is related to genos "birth, descent, race." In the bible, this is the name of the first book of the Old Testament.

    GENESIS

  • GENE
  • Male

    English

    GENE

    Short form of English Eugene, GENE means "well born."

    GENE

  • Longstreet
  • Surname or Lastname

    English

    Longstreet

    English : topographic name from Middle English lang, long ‘long’ + strete ‘road’.Translation of Dutch Langestraet, cognate with 1.The confederate general James Longstreet (1821–1904), was born in SC, came from an old Dutch family in New Netherland with the name Langestraet; he was the nephew of Augustus B. Longstreet, a Methodist clergyman born in Augusta, GA, in 1790.

    Longstreet

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Online names & meanings

  • Dharmapal | தர்மபால
  • Boy/Male

    Tamil

    Dharmapal | தர்மபால

    Protector of his religion

  • Athul | அதுல
  • Boy/Male

    Tamil

    Athul | அதுல

    Matchless or incomparable

  • Lerner
  • Surname or Lastname

    English

    Lerner

    English : occupational name for a scholar or schoolmaster, from an agent derivative of Middle English lern(en), which meant both ‘to learn’ and ‘to teach’ (Old English leornian).South German : habitational name for someone from Lern near Freising.South German : nickname from Middle High German lerner ‘pupil’, ‘schoolboy’.Jewish (Ashkenazic) : occupational name from Yiddish lerner ‘Talmudic student or scholar’.

  • Prabanjan | ப்ரபஂஜந
  • Boy/Male

    Tamil

    Prabanjan | ப்ரபஂஜந

  • Visheshiya
  • Girl/Female

    Indian

    Visheshiya

    Special

  • Laasya
  • Boy/Male

    Hindu, Indian

    Laasya

    Smile

  • Yathran
  • Boy/Male

    Indian, Tamil

    Yathran

    Lord Shiva

  • Miftah
  • Boy/Male

    Arabic, Muslim

    Miftah

    Key; Opener

  • Whitefield
  • Surname or Lastname

    English

    Whitefield

    English : habitational name from places in Greater Manchester and the Isle of Wight, named with Old English hwīt ‘white’ + feld ‘pasture’, ‘open country’ (see Whitfield).Americanized form of German Weissfeld (see Weisfeld).

  • Nangai
  • Girl/Female

    Assamese, Hindu, Indian, Kannada, Marathi, Sindhi, Tamil, Telugu

    Nangai

    Cultured Lady

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Other words and meanings similar to

ANTICANCER GENE

AI search in online dictionary sources & meanings containing ANTICANCER GENE

ANTICANCER GENE

  • Genevese
  • n. sing. & pl.

    A native or inhabitant of Geneva; collectively, the inhabitants of Geneva; people of Geneva.

  • Solicitor-general
  • n.

    The second law officer in the government of Great Britain; also, a similar officer under the United States government, who is associated with the attorney-general; also, the chief law officer of some of the States.

  • Genevese
  • a.

    Of or pertaining to Geneva, in Switzerland; Genevan.

  • Postmasters-general
  • pl.

    of Postmaster-general

  • Genethliacal
  • a.

    Genethliac.

  • Genethliac
  • n.

    One skilled in genethliacs.

  • Genevan
  • n.

    A native or inhabitant of Geneva.

  • Genet
  • n.

    Alt. of Genette

  • Genevan
  • a.

    Of or pertaining to Geneva, in Switzerland; Genevese.

  • Genette
  • n.

    The fur of the common genet (Genetta vulgaris); also, any skin dressed in imitation of this fur.

  • Genetically
  • adv.

    In a genetical manner.

  • Postmaster-general
  • n.

    The chief officer of the post-office department of a government. In the United States the postmaster-general is a member of the cabinet.

  • Genette
  • n.

    One of several species of small Carnivora of the genus Genetta, allied to the civets, but having the scent glands less developed, and without a pouch.

  • Genetic
  • a.

    Same as Genetical.

  • Genevan
  • n.

    A supported of Genevanism.

  • Genetical
  • a.

    Pertaining to, concerned with, or determined by, the genesis of anything, or its natural mode of production or development.