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Gene family
The ABC transporters, also known as ATP-binding cassette transporters, are a transport system superfamily that is one of the largest and possibly one
ABC_transporter
Cellular molecule transport mechanism against the concentration gradient
vacuolar ATPase ABC (ATP binding cassette) transporter: MDR, CFTR, etc. Adenosine triphosphate-binding cassette transporters (ABC transporters) comprise a
Active_transport
Main transmembrane structural unit of ATP-binding cassette transporter proteins
ABC transporter transmembrane domain is the main transmembrane structural unit of ATP-binding cassette transporter proteins, consisting of 6 to 10 alpha
Transmembrane domain of ABC transporters
Transmembrane_domain_of_ABC_transporters
Chinese-born American biochemist
on elucidating the structure and function of ATP-binding cassette (ABC) transporters. Chen was born in Changsha, China and graduated from Changsha No.
Jue_Chen_(scientist)
Protein found in humans
humans is encoded by the ABCB1 gene. P-gp is a well-characterized ABC-transporter (which transports a wide variety of substrates across extra- and intracellular
P-glycoprotein
Blood antigen set classification systems
Abstract: The human ATP-binding cassette (ABC) transporter ABCB6 has been described as a mitochondrial porphyrin transporter essential for heme biosynthesis, but
Human_blood_group_systems
Water-soluble domain of transmembrane ABC transporters
biology, ATP-binding domain of ABC transporters is a water-soluble domain of transmembrane ABC transporters. ABC transporters belong to the ATP-Binding Cassette
ATP-binding domain of ABC transporters
ATP-binding_domain_of_ABC_transporters
Protein found in humans
ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into
ABCC11
and C106‑2 represent the first and second flights of Dragon C106. Many Transporter and Bandwagon payloads are not public, or don't have a publicly revealed
List of Falcon 9 and Falcon Heavy launches
List_of_Falcon_9_and_Falcon_Heavy_launches
The ABC-type ferric hydroxamate transporter, (known also as the iron(III) hydroxamate ABC transporter and ATP phosphohydrolase [ABC-type, iron(III)
ABC-type ferric hydroxamate transporter
ABC-type_ferric_hydroxamate_transporter
South African – Israeli biophysicist
the University of Copenhagen, Stein worked out the kinetics of the ABC transporter P-glycoprotein (ABCB1) based on transport and ATPase measurements.
Wilfred_Stein
Genus of grass cultivated for grain
mildew. It is used intensively in wheat cultivation worldwide. It is an ABC transporter, producing a 'slow rusting'/adult resistance phenotype. Pm8 is a widely
Wheat
Genetic skin disease
erythroderma-like presentation. ABCA12 is an ATP-binding cassette transporter (ABC transporter), which is a member of a large family of proteins that hydrolyze
Harlequin-type_ichthyosis
Protein-coding gene in the species Homo sapiens
ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into
ABCD4
Species of archaeon
burtonii has a distinct lack of identifiable ABC transporters for peptides. This lack of identifiable ABC-transporter permease for peptides constitutes a major
Methanococcoides_burtonii
Physiological molecule and therapeutic drug
N-acetyl-D-glucosamine to the nascent polysaccharide as it is extruded via ABC-transporter through the cell membrane into the extracellular space. The term fasciacyte
Hyaluronic_acid
Sex-linked mutation
protein coded by the white gene functions as an ATP-binding cassette (ABC) transporter. It carries the precursors of the red and brown eye color pigments
White_(mutation)
Protein family
novo biosynthesis. Species with this protein always lack the ThiBPQ ABC transporter. In some species (e.g. Streptococcus mutans and Streptococcus pyogenes)
Thiamine_transporter
British biochemist, science writer and educator
his research on vacuolar proton (H+) pumps, ATP-binding cassette (ABC) transporters, and phytochelatin (PC) synthase. His early work on plant vacuolar
Philip_A._Rea
Biological database
biological database for the adenosine triphosphate-binding cassette (ABC) transporters encoded by completely sequenced archaeal and bacterial genomes. These
ABCdb
Protein-coding gene in the species Homo sapiens
this gene is included in the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular
ABCG2
Biochemistry
254. PMID 19710689. Ishikawa, Toshihisa; Toyoda, Yu (2016). Human ABC Transporter ABCC11: Looking Back Pioneers' Odyssey and Creating a New Path Toward
Biochemistry_of_body_odor
Foreign chemical substance found within an organism
is the use of ATP-binding cassette (ABC) transporters, which is largely exhibited in insects. Such transporters contribute to resistance by enabling
Xenobiotic
Genetically-inherited lipid metabolic disorder
(ABCG5 and ABCG8) located in chromosome 2 in band 2p21 and encode for ABC transporter proteins named sterolin-1 and sterolin-2, respectively. The two proteins
Sitosterolemia
Protein family
may comprise the membrane component of an ABC (ATP binding cassette) transporter complex. This transporter may be necessary for transport of some component
Cytochrome c assembly protein family
Cytochrome_c_assembly_protein_family
Mammalian protein found in humans
as the gene linked with cystic fibrosis. The CFTR gene codes for an ABC transporter-class ion channel protein that conducts chloride and bicarbonate ions
Cystic fibrosis transmembrane conductance regulator
Cystic_fibrosis_transmembrane_conductance_regulator
Protein-coding gene in the species Homo sapiens
ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra-and intra-cellular membranes. ABC genes are divided into
ABCC1
Pharmaceutical drug
resistance in cancer. Biricodar is considered a second-generation ABC transporter inhibitor and has been described as one of the most famous foundational
Biricodar
Family of proteins
component (DctP) of a transporter that recognized these compounds, which they assumed would form part of a typical ABC transporter, but when they sequenced
Tripartite ATP-independent periplasmic transporter
Tripartite_ATP-independent_periplasmic_transporter
Group of exotoxins from bacteria
(between the IM and OM). Type 1 secretion system components include: an ABC transporter (TC# 3.A.1), a membrane fusion protein (MFP; TC# 8.A.1), and an outer
RTX_toxin
Class of transport proteins
ZnuABC is a high-affinity transporter specialized for transporting zinc ions as part of a system for metal ion homeostasis in bacteria. The complex is
ZnuABC
Protein-coding gene in humans
complex in the respiratory chain. It is not related to the family of ABC transporter proteins. Expression of this gene is induced by the tumor suppressor
COQ8A
Protein-coding gene in humans
is encoded by the ABCB11 gene. The product of the ABCB11 gene is an ABC transporter named BSEP (bile salt export pump), or sPgp (sister of P-glycoprotein)
ABCB11
Gene profile for C10orf88 (aka PAAT)
contains an ABC transporter domain predicted to associate with Type II ABC transporters. PAAT physically interacts with mitochondrial inner membrane ABC transporters
PAAT_(protein)
Protein-coding gene in the species Homo sapiens
ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into
ABCC6
Transmembrane protein that moves ions across a biological membrane
phosphorylation, A-type ATPases that transfer anions, and ABC transporters (ATP binding cassette transporters) that transport a broad set of molecules. Examples
Ion_transporter
Protein-coding gene in the species Homo sapiens
ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into
ABCA2
Membrane protein involved in transportation
P-P-bond-hydrolysis-driven transporters (a.k.a. ATP-driven pumps, or transport ATPases): ATP-binding cassette transporter (ABC transporter), such as MDR, CFTR
Membrane_transport_protein
Protein-coding gene in the species Homo sapiens
ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into
ABCB6
Protein family
Transporter associated with antigen processing (TAP) protein complex belongs to the ATP-binding-cassette transporter family. It delivers cytosolic peptides
Transporter associated with antigen processing
Transporter_associated_with_antigen_processing
Regulon associated with the catabolism of maltose and maltodextrins
another ABC transporter, a part of the phosphoenolpyruvate-dependent phosphotransferase system (PTS). In S. pyogenes, there are two ABC transporter operons
Mal_regulon
Signaling molecule enabling detection and response to cell-population density
cleavage of a 41-amino acid precursor peptide (ComC); is secreted by an ABC transporter (ComAB); and is detected by a sensor kinase protein (ComD) once it
Autoinducer
Protein-coding gene in the species Homo sapiens
inner surface of the plasma membrane, and the chains are extruded via ABC-Transporter into the extracellular space. It serves a variety of functions, including
HAS2
Biologically active pigment made by bacteria and fungi
PMID 35482661. Hunter, Ryan C.; Newman, Dianne K. (2010). "A Putative ABC Transporter, HatABCDE, is among Molecular Determinants of Pyomelanin Production
Pyomelanin
Protein-coding gene in humans
membrane-spanning protein that in humans is encoded by the ABCB5 gene. ABCB5 is an ABC transporter and P-glycoprotein family member principally expressed in physiological
ABCB5
Mammalian protein found in humans
high-energy inorganic phosphate to carry out change in conformation of the ABC transporter. Transcribed ABCA4 forms into a heterodimer: the two dimerized compartments
ABCA4
Species of bacterium
circular genome for virulence factors like ATP-binding cassette (ABC) transporters and a 0.98 Mb circular megaplasmid for substrate utilization enzymes
Enterococcus_raffinosus
Class of enzymes
The ABC-type oligopeptide transporter (EC 7.4.2.6) or oligopeptide permease is an enzyme that catalyzes the chemical reaction ATP + H2O + oligopeptide(out)
ABC-type oligopeptide transporter
ABC-type_oligopeptide_transporter
Species of fungus
8%. The C. auris genome was found to encode several genes for the ABC transporter family, a major facilitator superfamily, which helps to explain its
Candida_auris
Energy-carrying molecule in living cells
Transport is mediated by ATP binding cassette transporters. The human genome encodes 48 ABC transporters, that are used for exporting drugs, lipids, and
Adenosine_triphosphate
Genetic disease in which elastic fibers in certain tissues harden
mutations in the MRP6 gene encoding a transmembrane ATP-binding cassette (ABC) transporter". primary. Proceedings of the National Academy of Sciences of the United
Pseudoxanthoma_elasticum
Chemical compound
from Escherichia coli, the SiaPQM TRAP transporter from Haemophilus influenzae and the SatABCD ABC transporter from Haemophilus ducreyi. In Japan, Neu5Ac
N-Acetylneuraminic_acid
Chemical compound
subsequently transferred into the bacterial cytoplasm via the use of ABC transporters. The biosynthetic pathway of bacillibactin was first identified by
Bacillibactin
Two-wheeled, self-balancing personal vehicle
Segway (/ˈsɛɡweɪ/ SEG-way) was a two-wheeled, self-balancing personal transporter invented by Dean Kamen. The name is a registered trademark of Segway
Segway
Calcium channel blocker medication
another study with ponies. Verapamil inhibits the ATP-binding cassette (ABC) transporter family of proteins found in stem cells and has been used to study cancer
Verapamil
RNA family
RNA. RydC is thought to regulate a mRNA, yejABEF, which encodes an ABC transporter protein. RydC is known to bind the Hfq protein, which causes a conformational
RydC_RNA
Protein found in humans
multispecific organic anion transporter 1 (cMOAT). MRP2 is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various
ATP-binding cassette sub-family C member 2
ATP-binding_cassette_sub-family_C_member_2
Fluorescent dye and complexometric indicator
proteins (ABC transporters ATP-binding cassette transporter genes) in intact cells as it is an excellent substrate of the multidrug resistance transporter 1 (MDR1)
Calcein
Protein-coding gene in the species Homo sapiens
peptide transporter 2. The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins
TAP2
Protein with oligosaccharide modifications
effects of antitumor drugs. P-glycoprotein, or multidrug transporter (MDR1), is a type of ABC transporter that transports compounds out of cells. This transportation
Glycoprotein
Protein-coding gene in the species Homo sapiens
ABC-type organic anion transporter ABCA8 is a protein that in humans is encoded by the ABCA8 gene. The membrane-associated protein encoded by this gene
ABCA8
Protein-coding gene in humans
ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into
ABCA3
Pathogenic genus of Gram-negative bacteria
periplasmic serine endoprotease DegP precursor, DNA polymerase I, and ABC transporter permease, that are specifically present in different species of the
Legionella
ATP or helping with the construction of the ATP-binding cassette (ABC) transporter. The ATP molecule binds to the connecting point of each subunit of
ATP-binding_motif
Protein of the immune system
the ER is accomplished by the transporter associated with antigen processing (TAP). TAP is a member of the ABC transporter family and is a heterodimeric
MHC_class_I
Protein-coding gene in the species Homo sapiens
inner surface of the plasma membrane, and the chains are extruded via ABC-transporter into the extracellular space. It serves a variety of functions, including
HAS1
family ABC transporters Antiporter Aquaporins Globin Major facilitator superfamily Neurotransmitter transporter GABA transporter Glutamate transporter Glycine
List_of_gene_families
general public. Kubanek has three patents filed in the United States: ABC transporter ligand GATX1, Compounds and compositions useful in the treatment of
Julia_Kubanek
Protein-coding gene in the species Homo sapiens
ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into
ABCF2
Group of disorders characterised by degeneration of white matter in the brain
(X-ALD), a mutation occurs in the peroxisomal ATP-binding cassette (ABC transporter). This leads to cerebral inflammatory demyelination caused by myelin
Leukodystrophy
Protein-coding gene in the species Homo sapiens
ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into
ABCG8
Class of enzymes
phosphohydrolase (maltose-importing). This enzyme is a member of the ABC Transporter family. As of late 2007, two structures have been solved for this class
Maltose-transporting_ATPase
Chemical compound
Clofarabine-resistance arises from decreased deoxycytidine kinase activity in vitro. ABC transporter ABCG2 promotes export of clofarabine-5´-monophosphate and thus limits
Clofarabine
Plasma membrane found in gram-negative bacteria
transport systems, namely, the O-antigen transporter Wzx (RfbX) and the ATP binding cassette (ABC) transporter MsbA that flips the lipid A-core moiety
Bacterial_outer_membrane
Mammalian protein found in Homo sapiens
ATP-binding cassette transporter ABCA1 (member 1 of human transporter sub-family ABCA), also known as the cholesterol efflux regulatory protein (CERP)
ABCA1
Protein-coding gene in the species Homo sapiens
ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into
ABCA7
Protein-coding gene in the species Homo sapiens
ATP-binding cassette sub-family A member 12 also known as ATP-binding cassette transporter 12 is a protein that in humans is encoded by the ABCA12 gene. ABCA12
ABCA12
Protein complexes that move compounds, generally toxic, out of bacterial cells
family (MATE). Of these, only the ABC superfamily is a primary transporter, the rest being secondary transporters utilizing proton or sodium gradient
Efflux_pump
Species of fruit fly
(January 1, 1998). "ABC transporters involved in transport of eye pigment precursors in Drosophila melanogaster". ABC Transporters: Biochemical, Cellular
Drosophila_melanogaster
Canadian microbiologist and researcher (born 1961)
these kinases are modulators of phase separation and clustering of an ABC transporter in Mtb. His early works also characterized and identified mycothiol
Yossef_Av-Gay
Protein-coding gene in humans
ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into
ABCB9
Family of protein complexes
–2 are two ‘half’ adenosine triphosphate binding (ATP) cassette (ABC) transporters which have been found to be indispensable for the regulation of sterol
Sterolin
Class of enzymes
phosphohydrolase (monosaccharide-importing). This enzyme participates in abc transporters - general. As of late 2007, only one structure has been solved for
Monosaccharide-transporting ATPase
Monosaccharide-transporting_ATPase
Italian botanist
Bovet, L., Fukao, Y., Düchtig, P., ... & Geisler, M. (2005). MDR‐like ABC transporter AtPGP4 is involved in auxin‐mediated lateral root and root hair development
Stefano_Mancuso
Odor produced by a living animal
Toyoda Y, Yoshiura K, Niikawa N (2012). "Pharmacogenetics of human ABC transporter ABCC11: new insights into apocrine gland growth and metabolite secretion"
Body_odor
Family of copepods
Alvinerie; Jozef Vercruysse; Roger K. Prichard; Peter Geldhof (2008). "ABC transporter modulation: a strategy to enhance the activity of macrocyclic lactone
Sea_louse
Order of Gram-negative bacteria
indels were reported for the order in proteins annotated as a peptide ABC transporter permease, the elongation factor P-like protein YeiP, L-arabinose isomerase
Enterobacterales
Protein-coding gene in the species Homo sapiens
ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into
ABCF1
Species of bacterium
peroxidase -like protein, a cytochrome c -like protein and a phosphate ABC transporter inner membrane protein- like protein. A functioning TAT pathway is
Moraxella_catarrhalis
Species of bacterium
retrieved 2026-07-12 Biswas S, Biswas I (April 2011). "Role of VltAB, an ABC transporter complex, in viologen tolerance in Streptococcus mutans". Antimicrobial
Streptococcus_mutans
Family of bacteria
RNA helicase, tRNA pseudouridine(13) synthase TruD, glycine/betaine ABC transporter ATP-binding protein, superoxide dismutase, and stationary phase inducible
Erwiniaceae
Chemical compound
(681-851 aa) HisG-family ATP phosphoribosyltransferase domain. Cns4 is an ABC transporter, specifically of the putative pleiotropic drug resistance (PDR) family
Cordycepin
Antifungal chemical compound
azole antifungal agents: characterization of CDR2, a new multidrug ABC transporter gene". Microbiology. 143 (Pt 2): 405–416. doi:10.1099/00221287-143-2-405
Ketoconazole
Species of bacterium
Linton, KJ; Cooper, HN; Hunter, IS; Leadlay, PF (February 1994). "An ABC-transporter from Streptomyces longisporoflavus confers resistance to the polyether-ionophore
Streptomyces_longisporoflavus
Controlled release of substances by cells or tissues
on the membrane. This signal sequence is extremely specific for the ABC transporter. The HlyAB complex stimulates HlyD which begins to uncoil and reaches
Secretion
RNA family
Masatoshi; Chao, Yanjie; Vogel, Jörg (2015-06-03). "Cross talk between ABC transporter mRNAs via a target mRNA-derived sponge of the GcvB small RNA". The
GcvB_RNA
Direct extension and penetration by cancer cells into neighboring tissues
trigger EMT and, at the same time, positively regulate the activity of ABC transporters include TWIST1, Snail, etc. There potentially exists a strong association
Invasion_(cancer)
21st-century American biologist
1875b, PMID 17185584) Reyes, CL; Chang, G (2005). "Structure of the ABC transporter MsbA in complex with ADP.vanadate and lipopolysaccharide". Science
Geoffrey_Chang
Chemical reactions and pathways
PMID 14990804. Woodson JD, Reynolds AA, Escalante-Semerena JC (2005). "ABC Transporter for Corrinoids in Halobacterium sp. Strain NRC-1". Journal of Bacteriology
Cobalamin_biosynthesis
Topics referred to by the same term
ABC, abc, or Abc in Wiktionary, the free dictionary. ABC, abc, or Abc commonly refers to: ABC, the first three letters of the Latin script ABC, abc,
ABC
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