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Protein found in humans
the ERBB3 gene. ErbB3 is a member of the epidermal growth factor receptor (EGFR/ERBB) family of receptor tyrosine kinases. The kinase-impaired ErbB3 is
ERBB3
Pharmaceutical compound
emtansine Kinase inhibitors: Afatinib Lapatinib Mubritinib Neratinib Tucatinib ErbB3/HER3 Agonists: Neuregulins (heregulins) (1, 2, 6 (neuroglycan C)) Antibodies:
Brelgometon
Tricyclic antidepressant
emtansine Kinase inhibitors: Afatinib Lapatinib Mubritinib Neratinib Tucatinib ErbB3/HER3 Agonists: Neuregulins (heregulins) (1, 2, 6 (neuroglycan C)) Antibodies:
Amitriptyline
Protein-coding gene in the species Homo sapiens
Proliferation-associated protein 2G4 (PA2G4) also known as ErbB3-binding protein 1 (EBP1) is a protein that in humans is encoded by the PA2G4 gene. This
PA2G4
TrkA and TrkB positive modulator
emtansine Kinase inhibitors: Afatinib Lapatinib Mubritinib Neratinib Tucatinib ErbB3/HER3 Agonists: Neuregulins (heregulins) (1, 2, 6 (neuroglycan C)) Antibodies:
ACD856
Enzyme
are actually pseudokinases, without catalytic activity (EPHA10, EPHB6, ERBB3, PTK7, ROR1, ROR2, RYK, and STYK1). Receptor tyrosine kinases play pivotal
Tyrosine_kinase
Family of proteins
In humans, the family includes Her1 (EGFR, ErbB1), Her2 (ErbB2), Her3 (ErbB3), and Her4 (ErbB4). The gene symbol, ErbB, is derived from the name of a
ErbB
Medication
emtansine Kinase inhibitors: Afatinib Lapatinib Mubritinib Neratinib Tucatinib ErbB3/HER3 Agonists: Neuregulins (heregulins) (1, 2, 6 (neuroglycan C)) Antibodies:
Trastuzumab_deruxtecan
Medication for treatment of non-small-cell lung cancer
by amplification of the hepatocyte growth factor receptor, which drives ERBB3 dependent activation of PI3K. Rash occurs in the majority of patients. This
Erlotinib
Corticosteroid medication
emtansine Kinase inhibitors: Afatinib Lapatinib Mubritinib Neratinib Tucatinib ErbB3/HER3 Agonists: Neuregulins (heregulins) (1, 2, 6 (neuroglycan C)) Antibodies:
Dexamethasone
Class of proteins
emtansine Kinase inhibitors: Afatinib Lapatinib Mubritinib Neratinib Tucatinib ErbB3/HER3 Agonists: Neuregulins (heregulins) (1, 2, 6 (neuroglycan C)) Antibodies:
Hemopoietic_growth_factor
Group of signal transduction pathways involved in embryonic development
emtansine Kinase inhibitors: Afatinib Lapatinib Mubritinib Neratinib Tucatinib ErbB3/HER3 Agonists: Neuregulins (heregulins) (1, 2, 6 (neuroglycan C)) Antibodies:
Wnt_signaling_pathway
Generating of neurons from neural stem cells in adults
emtansine Kinase inhibitors: Afatinib Lapatinib Mubritinib Neratinib Tucatinib ErbB3/HER3 Agonists: Neuregulins (heregulins) (1, 2, 6 (neuroglycan C)) Antibodies:
Adult_neurogenesis
Medication for macular degeneration
emtansine Kinase inhibitors: Afatinib Lapatinib Mubritinib Neratinib Tucatinib ErbB3/HER3 Agonists: Neuregulins (heregulins) (1, 2, 6 (neuroglycan C)) Antibodies:
Faricimab
Peptide hormone
emtansine Kinase inhibitors: Afatinib Lapatinib Mubritinib Neratinib Tucatinib ErbB3/HER3 Agonists: Neuregulins (heregulins) (1, 2, 6 (neuroglycan C)) Antibodies:
Insulin
Anti-cancer medication
emtansine Kinase inhibitors: Afatinib Lapatinib Mubritinib Neratinib Tucatinib ErbB3/HER3 Agonists: Neuregulins (heregulins) (1, 2, 6 (neuroglycan C)) Antibodies:
Dabrafenib
Bispecific Antibody That Targets the ErbB2/ErbB3 Oncogenic Unit and Inhibits Heregulin-Induced Activation of ErbB3. Molecular Cancer Therapeutics OpenWorm
Modelling_biological_systems
Signaling glycoprotein regulating cell proliferation
emtansine Kinase inhibitors: Afatinib Lapatinib Mubritinib Neratinib Tucatinib ErbB3/HER3 Agonists: Neuregulins (heregulins) (1, 2, 6 (neuroglycan C)) Antibodies:
Platelet-derived growth factor
Platelet-derived_growth_factor
Chemical compound
emtansine Kinase inhibitors: Afatinib Lapatinib Mubritinib Neratinib Tucatinib ErbB3/HER3 Agonists: Neuregulins (heregulins) (1, 2, 6 (neuroglycan C)) Antibodies:
Dasatinib
Protein with antiangiogenic properties
kinases (EC 2.7.10.1) Growth factor receptors EGF receptor family EGFR ERBB2 ERBB3 ERBB4 Insulin receptor family IGF1R INSR INSRR PDGF receptor family CSF1R
Soluble fms-like tyrosine kinase-1
Soluble_fms-like_tyrosine_kinase-1
Experimental drug for neurodegenerative disorders
emtansine Kinase inhibitors: Afatinib Lapatinib Mubritinib Neratinib Tucatinib ErbB3/HER3 Agonists: Neuregulins (heregulins) (1, 2, 6 (neuroglycan C)) Antibodies:
Cerebrolysin
Chemical compound used in the treatment of tumors
emtansine Kinase inhibitors: Afatinib Lapatinib Mubritinib Neratinib Tucatinib ErbB3/HER3 Agonists: Neuregulins (heregulins) (1, 2, 6 (neuroglycan C)) Antibodies:
Toceranib
Protein or other substance that stimulates cellular proliferation
emtansine Kinase inhibitors: Afatinib Lapatinib Mubritinib Neratinib Tucatinib ErbB3/HER3 Agonists: Neuregulins (heregulins) (1, 2, 6 (neuroglycan C)) Antibodies:
Growth_factor
Primary male sex hormone
emtansine Kinase inhibitors: Afatinib Lapatinib Mubritinib Neratinib Tucatinib ErbB3/HER3 Agonists: Neuregulins (heregulins) (1, 2, 6 (neuroglycan C)) Antibodies:
Testosterone
Medical condition
able to interact, they trigger an activation loop. As a result, the ErbB2/ErbB3 signaling pathway becomes constitutively activated, cell–cell interactions
Signet_ring_cell_carcinoma
Monoclonal antibody
emtansine Kinase inhibitors: Afatinib Lapatinib Mubritinib Neratinib Tucatinib ErbB3/HER3 Agonists: Neuregulins (heregulins) (1, 2, 6 (neuroglycan C)) Antibodies:
Pegfilgrastim
Protein-coding gene in the species Homo sapiens
emtansine Kinase inhibitors: Afatinib Lapatinib Mubritinib Neratinib Tucatinib ErbB3/HER3 Agonists: Neuregulins (heregulins) (1, 2, 6 (neuroglycan C)) Antibodies:
FGF19
Protein-coding gene in the species Homo sapiens
Ledesma J, Yu N, Gassmann M, Lai C (May 1997). "Neuregulin-2, a new ligand of ErbB3/ErbB4-receptor tyrosine kinases". Nature. 387 (6632): 512–6. Bibcode:1997Natur
Neuregulin_2
Combination cancer medication
emtansine Kinase inhibitors: Afatinib Lapatinib Mubritinib Neratinib Tucatinib ErbB3/HER3 Agonists: Neuregulins (heregulins) (1, 2, 6 (neuroglycan C)) Antibodies:
Avutometinib/defactinib
Protein that stimulates cell division and differentiation
emtansine Kinase inhibitors: Afatinib Lapatinib Mubritinib Neratinib Tucatinib ErbB3/HER3 Agonists: Neuregulins (heregulins) (1, 2, 6 (neuroglycan C)) Antibodies:
Epidermal_growth_factor
or gastroesophageal junction adenocarcinoma Duligotuzumab mab humanized ERBB3 (HER3) testicular cancer Dupilumab Dupixent mab human IL-4Rα Y atopic dermatitis
List of therapeutic monoclonal antibodies
List_of_therapeutic_monoclonal_antibodies
Chemical compound
emtansine Kinase inhibitors: Afatinib Lapatinib Mubritinib Neratinib Tucatinib ErbB3/HER3 Agonists: Neuregulins (heregulins) (1, 2, 6 (neuroglycan C)) Antibodies:
Cabozantinib
Protein-coding gene in the species Homo sapiens
Ledesma J, Yu N, Gassmann M, Lai C (May 1997). "Neuregulin-2, a new ligand of ErbB3/ErbB4-receptor tyrosine kinases". Nature. 387 (6632): 512–6. Bibcode:1997Natur
ERBB4
Protein that stimulates red blood cell production
emtansine Kinase inhibitors: Afatinib Lapatinib Mubritinib Neratinib Tucatinib ErbB3/HER3 Agonists: Neuregulins (heregulins) (1, 2, 6 (neuroglycan C)) Antibodies:
Erythropoietin
Medication
emtansine Kinase inhibitors: Afatinib Lapatinib Mubritinib Neratinib Tucatinib ErbB3/HER3 Agonists: Neuregulins (heregulins) (1, 2, 6 (neuroglycan C)) Antibodies:
Fruquintinib
Pharmaceutical drug
emtansine Kinase inhibitors: Afatinib Lapatinib Mubritinib Neratinib Tucatinib ErbB3/HER3 Agonists: Neuregulins (heregulins) (1, 2, 6 (neuroglycan C)) Antibodies:
Alacizumab_pegol
Lymphocyte protein
kinases (EC 2.7.10.1) Growth factor receptors EGF receptor family EGFR ERBB2 ERBB3 ERBB4 Insulin receptor family IGF1R INSR INSRR PDGF receptor family CSF1R
Tyrosin-protein_kinase_Lck
Pharmaceutical drug
emtansine Kinase inhibitors: Afatinib Lapatinib Mubritinib Neratinib Tucatinib ErbB3/HER3 Agonists: Neuregulins (heregulins) (1, 2, 6 (neuroglycan C)) Antibodies:
Ranibizumab
Chemical compound
emtansine Kinase inhibitors: Afatinib Lapatinib Mubritinib Neratinib Tucatinib ErbB3/HER3 Agonists: Neuregulins (heregulins) (1, 2, 6 (neuroglycan C)) Antibodies:
Fulranumab
Family of biomolecules
emtansine Kinase inhibitors: Afatinib Lapatinib Mubritinib Neratinib Tucatinib ErbB3/HER3 Agonists: Neuregulins (heregulins) (1, 2, 6 (neuroglycan C)) Antibodies:
Neurotrophic_factors
Protein found in humans
emtansine Kinase inhibitors: Afatinib Lapatinib Mubritinib Neratinib Tucatinib ErbB3/HER3 Agonists: Neuregulins (heregulins) (1, 2, 6 (neuroglycan C)) Antibodies:
Insulin-like_growth_factor_1
Monoclonal antibody
emtansine Kinase inhibitors: Afatinib Lapatinib Mubritinib Neratinib Tucatinib ErbB3/HER3 Agonists: Neuregulins (heregulins) (1, 2, 6 (neuroglycan C)) Antibodies:
Futuximab
American engineer and academic
effects on the glass transition. Radhakrishnan's 2010 paper investigated ErbB3/HER3 kinase activity, revealing its capacity for autophosphorylation and
Ravi_Radhakrishnan
Drug for the treatment of lung carninoma
emtansine Kinase inhibitors: Afatinib Lapatinib Mubritinib Neratinib Tucatinib ErbB3/HER3 Agonists: Neuregulins (heregulins) (1, 2, 6 (neuroglycan C)) Antibodies:
Dacomitinib
Glial cell type
PMID 16136171. S2CID 7540462. Britisch, S.; et al. (1998). "The ErbB2 and ErbB3 receptors and their ligand, neuregulin-1 are essential for development of
Schwann_cell
Cancer treatment medicine
emtansine Kinase inhibitors: Afatinib Lapatinib Mubritinib Neratinib Tucatinib ErbB3/HER3 Agonists: Neuregulins (heregulins) (1, 2, 6 (neuroglycan C)) Antibodies:
Sorafenib
Anticancer medication
emtansine Kinase inhibitors: Afatinib Lapatinib Mubritinib Neratinib Tucatinib ErbB3/HER3 Agonists: Neuregulins (heregulins) (1, 2, 6 (neuroglycan C)) Antibodies:
Trametinib
Mammalian protein found in Homo sapiens
emtansine Kinase inhibitors: Afatinib Lapatinib Mubritinib Neratinib Tucatinib ErbB3/HER3 Agonists: Neuregulins (heregulins) (1, 2, 6 (neuroglycan C)) Antibodies:
Hepatocyte_growth_factor
Protein-coding gene in the species Homo sapiens
GATA4 inactivation, with GATA4-null mice, leads to down regulation of Erbb3 and altered Erk expression, two other important molecules in EMT and ventricular
GATA4
Chemical compound
emtansine Kinase inhibitors: Afatinib Lapatinib Mubritinib Neratinib Tucatinib ErbB3/HER3 Agonists: Neuregulins (heregulins) (1, 2, 6 (neuroglycan C)) Antibodies:
Ponazuril
Medication
emtansine Kinase inhibitors: Afatinib Lapatinib Mubritinib Neratinib Tucatinib ErbB3/HER3 Agonists: Neuregulins (heregulins) (1, 2, 6 (neuroglycan C)) Antibodies:
Filgrastim
Protein-coding gene in humans
emtansine Kinase inhibitors: Afatinib Lapatinib Mubritinib Neratinib Tucatinib ErbB3/HER3 Agonists: Neuregulins (heregulins) (1, 2, 6 (neuroglycan C)) Antibodies:
Betacellulin
Chemical compound
emtansine Kinase inhibitors: Afatinib Lapatinib Mubritinib Neratinib Tucatinib ErbB3/HER3 Agonists: Neuregulins (heregulins) (1, 2, 6 (neuroglycan C)) Antibodies:
ANA-12
Combination drug
emtansine Kinase inhibitors: Afatinib Lapatinib Mubritinib Neratinib Tucatinib ErbB3/HER3 Agonists: Neuregulins (heregulins) (1, 2, 6 (neuroglycan C)) Antibodies:
Mecasermin_rinfabate
Mammalian protein found in humans
emtansine Kinase inhibitors: Afatinib Lapatinib Mubritinib Neratinib Tucatinib ErbB3/HER3 Agonists: Neuregulins (heregulins) (1, 2, 6 (neuroglycan C)) Antibodies:
C-fos-induced_growth_factor
Protein found in humans
emtansine Kinase inhibitors: Afatinib Lapatinib Mubritinib Neratinib Tucatinib ErbB3/HER3 Agonists: Neuregulins (heregulins) (1, 2, 6 (neuroglycan C)) Antibodies:
Brain-derived neurotrophic factor
Brain-derived_neurotrophic_factor
Class of enzymes
GW583340, gefitinib, erlotinib, tyrphostins AG879 and AG1478 ErbB2 ERBB2 " ErbB3 ERBB3 " NRG-1, NRG-2 GW583340, gefitinib, erlotinib, tyrphostins AG879 and
Enzyme-linked_receptor
Chemical compound
emtansine Kinase inhibitors: Afatinib Lapatinib Mubritinib Neratinib Tucatinib ErbB3/HER3 Agonists: Neuregulins (heregulins) (1, 2, 6 (neuroglycan C)) Antibodies:
Crenolanib
Protein-coding gene in the species Homo sapiens
emtansine Kinase inhibitors: Afatinib Lapatinib Mubritinib Neratinib Tucatinib ErbB3/HER3 Agonists: Neuregulins (heregulins) (1, 2, 6 (neuroglycan C)) Antibodies:
Angiopoietin_4
Chemical compound
emtansine Kinase inhibitors: Afatinib Lapatinib Mubritinib Neratinib Tucatinib ErbB3/HER3 Agonists: Neuregulins (heregulins) (1, 2, 6 (neuroglycan C)) Antibodies:
Dihexa
Protein capable of worsening malignant diseases
emtansine Kinase inhibitors: Afatinib Lapatinib Mubritinib Neratinib Tucatinib ErbB3/HER3 Agonists: Neuregulins (heregulins) (1, 2, 6 (neuroglycan C)) Antibodies:
Hepatoma-derived growth factor
Hepatoma-derived_growth_factor
Protein-coding gene in the species Homo sapiens
cells enhances the coupling of EGF signalling to PI 3-kinase and Akt, via erbB3 phosphorylation". Oncogene. 19 (48): 5471–6. doi:10.1038/sj.onc.1203931
PTK6
Protein-coding gene in Homo sapiens
information available about the other genes of the family. NRGs bind to the ERBB3 and ERBB4 tyrosine kinase receptors; they then form homodimers or heterodimers
Neuregulin_3
Family of proteins
emtansine Kinase inhibitors: Afatinib Lapatinib Mubritinib Neratinib Tucatinib ErbB3/HER3 Agonists: Neuregulins (heregulins) (1, 2, 6 (neuroglycan C)) Antibodies:
Neurotrophin
Protein-coding gene in the species Homo sapiens
emtansine Kinase inhibitors: Afatinib Lapatinib Mubritinib Neratinib Tucatinib ErbB3/HER3 Agonists: Neuregulins (heregulins) (1, 2, 6 (neuroglycan C)) Antibodies:
PDGFB
Recombinant human monoclonal antibody
emtansine Kinase inhibitors: Afatinib Lapatinib Mubritinib Neratinib Tucatinib ErbB3/HER3 Agonists: Neuregulins (heregulins) (1, 2, 6 (neuroglycan C)) Antibodies:
Necitumumab
Kinase that plays a role in B cell development
kinases (EC 2.7.10.1) Growth factor receptors EGF receptor family EGFR ERBB2 ERBB3 ERBB4 Insulin receptor family IGF1R INSR INSRR PDGF receptor family CSF1R
Bruton's_tyrosine_kinase
Medication
emtansine Kinase inhibitors: Afatinib Lapatinib Mubritinib Neratinib Tucatinib ErbB3/HER3 Agonists: Neuregulins (heregulins) (1, 2, 6 (neuroglycan C)) Antibodies:
Ponatinib
Protein found in humans
kinases (EC 2.7.10.1) Growth factor receptors EGF receptor family EGFR ERBB2 ERBB3 ERBB4 Insulin receptor family IGF1R INSR INSRR PDGF receptor family CSF1R
Tyrosine-protein_kinase_BLK
Protein-coding gene in the species Homo sapiens
emtansine Kinase inhibitors: Afatinib Lapatinib Mubritinib Neratinib Tucatinib ErbB3/HER3 Agonists: Neuregulins (heregulins) (1, 2, 6 (neuroglycan C)) Antibodies:
Placental_growth_factor
Pharmaceutical drug
emtansine Kinase inhibitors: Afatinib Lapatinib Mubritinib Neratinib Tucatinib ErbB3/HER3 Agonists: Neuregulins (heregulins) (1, 2, 6 (neuroglycan C)) Antibodies:
Ramucirumab
Mammalian protein found in humans
kinases (EC 2.7.10.1) Growth factor receptors EGF receptor family EGFR ERBB2 ERBB3 ERBB4 Insulin receptor family IGF1R INSR INSRR PDGF receptor family CSF1R
TIE1
Pharmaceutical drug
emtansine Kinase inhibitors: Afatinib Lapatinib Mubritinib Neratinib Tucatinib ErbB3/HER3 Agonists: Neuregulins (heregulins) (1, 2, 6 (neuroglycan C)) Antibodies:
Cetuximab
Family of proteins involved in anatomical development
emtansine Kinase inhibitors: Afatinib Lapatinib Mubritinib Neratinib Tucatinib ErbB3/HER3 Agonists: Neuregulins (heregulins) (1, 2, 6 (neuroglycan C)) Antibodies:
Fibroblast_growth_factor
Pharmaceutical drug
emtansine Kinase inhibitors: Afatinib Lapatinib Mubritinib Neratinib Tucatinib ErbB3/HER3 Agonists: Neuregulins (heregulins) (1, 2, 6 (neuroglycan C)) Antibodies:
Trofinetide
Protein-coding gene in the species Homo sapiens
kinases (EC 2.7.10.1) Growth factor receptors EGF receptor family EGFR ERBB2 ERBB3 ERBB4 Insulin receptor family IGF1R INSR INSRR PDGF receptor family CSF1R
Fibroblast growth factor receptor 4
Fibroblast_growth_factor_receptor_4
Protein-coding gene in humans
of protein localization to endoplasmic reticulum positive regulation of ERBB3 signaling pathway endoplasmic reticulum tubular network membrane organization
Reticulon_4
Protein found in humans
emtansine Kinase inhibitors: Afatinib Lapatinib Mubritinib Neratinib Tucatinib ErbB3/HER3 Agonists: Neuregulins (heregulins) (1, 2, 6 (neuroglycan C)) Antibodies:
Artemin
Chemical compound
emtansine Kinase inhibitors: Afatinib Lapatinib Mubritinib Neratinib Tucatinib ErbB3/HER3 Agonists: Neuregulins (heregulins) (1, 2, 6 (neuroglycan C)) Antibodies:
Cobimetinib
Protein-coding gene in humans
kinases (EC 2.7.10.1) Growth factor receptors EGF receptor family EGFR ERBB2 ERBB3 ERBB4 Insulin receptor family IGF1R INSR INSRR PDGF receptor family CSF1R
EPHA8
Mammalian protein found in Homo sapiens
kinases (EC 2.7.10.1) Growth factor receptors EGF receptor family EGFR ERBB2 ERBB3 ERBB4 Insulin receptor family IGF1R INSR INSRR PDGF receptor family CSF1R
LYN
Cancer medication
emtansine Kinase inhibitors: Afatinib Lapatinib Mubritinib Neratinib Tucatinib ErbB3/HER3 Agonists: Neuregulins (heregulins) (1, 2, 6 (neuroglycan C)) Antibodies:
Lapatinib
Chemical compound
emtansine Kinase inhibitors: Afatinib Lapatinib Mubritinib Neratinib Tucatinib ErbB3/HER3 Agonists: Neuregulins (heregulins) (1, 2, 6 (neuroglycan C)) Antibodies:
Imatinib
Protein found in humans
emtansine Kinase inhibitors: Afatinib Lapatinib Mubritinib Neratinib Tucatinib ErbB3/HER3 Agonists: Neuregulins (heregulins) (1, 2, 6 (neuroglycan C)) Antibodies:
Fibroblast_growth_factor_23
Gene involved in the most common form of dwarfism
kinases (EC 2.7.10.1) Growth factor receptors EGF receptor family EGFR ERBB2 ERBB3 ERBB4 Insulin receptor family IGF1R INSR INSRR PDGF receptor family CSF1R
Fibroblast growth factor receptor 3
Fibroblast_growth_factor_receptor_3
Medical usage of the prasterone compound
emtansine Kinase inhibitors: Afatinib Lapatinib Mubritinib Neratinib Tucatinib ErbB3/HER3 Agonists: Neuregulins (heregulins) (1, 2, 6 (neuroglycan C)) Antibodies:
Prasterone
Urinary system cancer that begins in the urinary bladder
common, including mutations in PIK3CA (in around 30% of tumors) and ERBB2/ERBB3 (up to 15% of tumors), and loss of TSC1 (50% of tumors). Major regulators
Bladder_cancer
Chemical compound
emtansine Kinase inhibitors: Afatinib Lapatinib Mubritinib Neratinib Tucatinib ErbB3/HER3 Agonists: Neuregulins (heregulins) (1, 2, 6 (neuroglycan C)) Antibodies:
Regorafenib
Protein-coding gene in the species Homo sapiens
kinases (EC 2.7.10.1) Growth factor receptors EGF receptor family EGFR ERBB2 ERBB3 ERBB4 Insulin receptor family IGF1R INSR INSRR PDGF receptor family CSF1R
EPH_receptor_A5
Protein-coding gene in the species Homo sapiens
kinases (EC 2.7.10.1) Growth factor receptors EGF receptor family EGFR ERBB2 ERBB3 ERBB4 Insulin receptor family IGF1R INSR INSRR PDGF receptor family CSF1R
VEGFR1
Family of proteins
emtansine Kinase inhibitors: Afatinib Lapatinib Mubritinib Neratinib Tucatinib ErbB3/HER3 Agonists: Neuregulins (heregulins) (1, 2, 6 (neuroglycan C)) Antibodies:
Ephrin
Protein-coding gene in the species Homo sapiens
emtansine Kinase inhibitors: Afatinib Lapatinib Mubritinib Neratinib Tucatinib ErbB3/HER3 Agonists: Neuregulins (heregulins) (1, 2, 6 (neuroglycan C)) Antibodies:
IGFBP7
Medication and naturally occurring steroid hormone
emtansine Kinase inhibitors: Afatinib Lapatinib Mubritinib Neratinib Tucatinib ErbB3/HER3 Agonists: Neuregulins (heregulins) (1, 2, 6 (neuroglycan C)) Antibodies:
Testosterone_(medication)
Cell cycle regulation pathway
Rinehart C, Arteaga CL (February 2012). "Feedback upregulation of HER3 (ErbB3) expression and activity attenuates antitumor effect of PI3K inhibitors"
PI3K/AKT/mTOR_pathway
Family of four EGF proteins
and activate the erbB family of receptor tyrosine kinases (erbB2 (HER2), erbB3 (HER3), and erbB4 (HER4)), functioning both as heterodimers and homodimers
Neuregulin
Chemical compound
emtansine Kinase inhibitors: Afatinib Lapatinib Mubritinib Neratinib Tucatinib ErbB3/HER3 Agonists: Neuregulins (heregulins) (1, 2, 6 (neuroglycan C)) Antibodies:
Molgramostim
ALK inhibitor for treatment of non-small-cell lung cancer
emtansine Kinase inhibitors: Afatinib Lapatinib Mubritinib Neratinib Tucatinib ErbB3/HER3 Agonists: Neuregulins (heregulins) (1, 2, 6 (neuroglycan C)) Antibodies:
Alectinib
Targeted cancer drug
emtansine Kinase inhibitors: Afatinib Lapatinib Mubritinib Neratinib Tucatinib ErbB3/HER3 Agonists: Neuregulins (heregulins) (1, 2, 6 (neuroglycan C)) Antibodies:
Vemurafenib
Class of enzymes
kinases (EC 2.7.10.1) Growth factor receptors EGF receptor family EGFR ERBB2 ERBB3 ERBB4 Insulin receptor family IGF1R INSR INSRR PDGF receptor family CSF1R
Receptor_tyrosine_kinase
Chemical compound
emtansine Kinase inhibitors: Afatinib Lapatinib Mubritinib Neratinib Tucatinib ErbB3/HER3 Agonists: Neuregulins (heregulins) (1, 2, 6 (neuroglycan C)) Antibodies:
Avapritinib
travel, tourism, insurance
ERBB3
ERBB3
ERBB3
ERBB3
ERBB3
ERBB3
ERBB3
ERBB3
ERBB3
travel, tourism, insurance