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Search references for CXCR2. Phrases containing CXCR2
See searches and references containing CXCR2!CXCR2
Protein encoding gene in humans
CXCR2 is a chemokine receptor that in humans is encoded by the CXCR2 gene. The protein encoded by this gene is a member of the G-protein-coupled receptor
CXCR2
Pharmacological agent class
CXCR2 antagonist are a class of pharmacological agents that inhibit the activity of the G-protein-coupled receptors (GPCR) CXCR2 receptor. Cxcr2 is involved
CXCR2_antagonist
Protein family
CXC chemokine receptors in mammals, named CXCR1 through CXCR6. CXCR1 and CXCR2 are closely related receptors that recognize CXC chemokines that possess
CXC_chemokine_receptors
Mammalian protein found in humans
serpentine receptors CXCR1 and CXCR2. Expression and affinity for IL-8 differs between the two receptors (CXCR1 > CXCR2). Through a chain of biochemical
Interleukin_8
Mammalian protein found in humans
both monomer and dimer and both forms are able to bind chemokine receptor CXCR2. However, CXCL1 chemokine is able to dimerize only at higher (micromolar)
CXCL1
Small cytokines or signaling proteins secreted by cells
express several receptors for chemokines: CCR1, CCR2, CCR3, CCR4, CCR5, CXCR2, and CXCR4. Ligands of these receptors CCL2 and CCL5 play an important role
Chemokine
Mammalian protein found in humans
mobilizes cells by interacting with a cell surface chemokine receptor called CXCR2. CXCL2, like related chemokines, is also a powerful neutrophil chemoattractant
CXCL2
Group of cytokines
serpentine receptors CXCR1 and CXCR2. Expression and affinity for IL-8 differs between the two receptors (CXCR1 > CXCR2). Through a chain of biochemical
Interleukin
Monoclonal antibody
chemokines (CXCL1-3 and CXCL5-8), thereby limiting signaling through CXCR1 and CXCR2". It was tested in clinical trials for hidradenitis suppurativa. Fragoso
Eltrekibart
Mammalian protein found in humans
chemotactic effects by interacting with the chemokine receptors CXCR1 and CXCR2. The gene for CXCL6 is located on human chromosome 4 in a cluster with other
CXCL6
Cascade of intracellular and molecular events for transmission/amplification of signals
encoding the chemokine receptor CXCR2; mutated cells underwent a malignant transformation due to the expression of CXCR2 in an active conformation despite
Signal_transduction
Drug used to treat allergic diseases
Tocilizumab Levilimab IL-7 Agonists: Interleukin 7 IL-8 See CXCR1 (IL-8Rα) and CXCR2 (IL-8Rβ) here instead. IL-9 Agonists: Interleukin 9 Antibodies: Enokizumab
Dupilumab
American cancer biologist
functionality and regulation of CXCR2, the chemokine receptor for MGSA, later named CXCL1. They demonstrated that CXCR2 plays a major role in angiogenesis
Ann_Richmond
Chemical compound
(CXCL8, GCP-1) Antagonists: Navarixin NAMs: Ladarixin Reparixin (repertaxin) CXCR2 (IL-8Rβ) Agonists: CXCL1 (MGSA) CXCL2 CXCL3 CXCL5 CXCL6 CXCL7 Emoctakin
Conolidine
Mammalian protein found in Homo sapiens
(GPCRs) CC CCR1 CCR2 CCRL2 CCR3 CCR4 CCR5 CCR6 CCR7 CCR8 CCR9 CCR10 CXC CXCR1 CXCR2 CXCR3 CXCR4 CXCR5 CXCR6 Other CX3C CX3CR1 XC XCR1 ACKR 1 2 3 4 5 CMKLR1
Interleukin-3_receptor
Protein-coding gene in the species Homo sapiens
Tocilizumab Levilimab IL-7 Agonists: Interleukin 7 IL-8 See CXCR1 (IL-8Rα) and CXCR2 (IL-8Rβ) here instead. IL-9 Agonists: Interleukin 9 Antibodies: Enokizumab
Interleukin-12_subunit_beta
Protein that binds to a cytokine
(GPCRs) CC CCR1 CCR2 CCRL2 CCR3 CCR4 CCR5 CCR6 CCR7 CCR8 CCR9 CCR10 CXC CXCR1 CXCR2 CXCR3 CXCR4 CXCR5 CXCR6 Other CX3C CX3CR1 XC XCR1 ACKR 1 2 3 4 5 CMKLR1
Cytokine_receptor
Protein family
(GPCRs) CC CCR1 CCR2 CCRL2 CCR3 CCR4 CCR5 CCR6 CCR7 CCR8 CCR9 CCR10 CXC CXCR1 CXCR2 CXCR3 CXCR4 CXCR5 CXCR6 Other CX3C CX3CR1 XC XCR1 ACKR 1 2 3 4 5 CMKLR1
CC_chemokine_receptors
Protein-coding gene in humans
(GPCRs) CC CCR1 CCR2 CCRL2 CCR3 CCR4 CCR5 CCR6 CCR7 CCR8 CCR9 CCR10 CXC CXCR1 CXCR2 CXCR3 CXCR4 CXCR5 CXCR6 Other CX3C CX3CR1 XC XCR1 ACKR 1 2 3 4 5 CMKLR1
Common_gamma_chain
Interleukin receptor
(GPCRs) CC CCR1 CCR2 CCRL2 CCR3 CCR4 CCR5 CCR6 CCR7 CCR8 CCR9 CCR10 CXC CXCR1 CXCR2 CXCR3 CXCR4 CXCR5 CXCR6 Other CX3C CX3CR1 XC XCR1 ACKR 1 2 3 4 5 CMKLR1
Interleukin-18_receptor
Mammalian protein found in humans
(GPCRs) CC CCR1 CCR2 CCRL2 CCR3 CCR4 CCR5 CCR6 CCR7 CCR8 CCR9 CCR10 CXC CXCR1 CXCR2 CXCR3 CXCR4 CXCR5 CXCR6 Other CX3C CX3CR1 XC XCR1 ACKR 1 2 3 4 5 CMKLR1
C-C_chemokine_receptor_type_6
Biopharmaceutical drug
Tocilizumab Levilimab IL-7 Agonists: Interleukin 7 IL-8 See CXCR1 (IL-8Rα) and CXCR2 (IL-8Rβ) here instead. IL-9 Agonists: Interleukin 9 Antibodies: Enokizumab
Ustekinumab
Phenomenon characterized by the cessation of cell division
MV, Augert A, Raguz S, et al. (June 2008). "Chemokine signaling via the CXCR2 receptor reinforces senescence". Cell. 133 (6): 1006–1018. doi:10.1016/j
Cellular_senescence
Protein in the tumor necrosis factor receptor superfamily
(GPCRs) CC CCR1 CCR2 CCRL2 CCR3 CCR4 CCR5 CCR6 CCR7 CCR8 CCR9 CCR10 CXC CXCR1 CXCR2 CXCR3 CXCR4 CXCR5 CXCR6 Other CX3C CX3CR1 XC XCR1 ACKR 1 2 3 4 5 CMKLR1
CD27
Protein-coding gene in the species Homo sapiens
(GPCRs) CC CCR1 CCR2 CCRL2 CCR3 CCR4 CCR5 CCR6 CCR7 CCR8 CCR9 CCR10 CXC CXCR1 CXCR2 CXCR3 CXCR4 CXCR5 CXCR6 Other CX3C CX3CR1 XC XCR1 ACKR 1 2 3 4 5 CMKLR1
Interleukin 1 receptor, type II
Interleukin_1_receptor,_type_II
Cytokine receptor
For example, when CXCL8 (IL-8) binds to its specific receptors, CXCR1 or CXCR2, a rise in intracellular calcium activates the enzyme phospholipase D (PLD)
Chemokine_receptor
Chemical compound
(CXCL8, GCP-1) Antagonists: Navarixin NAMs: Ladarixin Reparixin (repertaxin) CXCR2 (IL-8Rβ) Agonists: CXCL1 (MGSA) CXCL2 CXCL3 CXCL5 CXCL6 CXCL7 Emoctakin
Cenicriviroc
Immunosuppressive drug
Tocilizumab Levilimab IL-7 Agonists: Interleukin 7 IL-8 See CXCR1 (IL-8Rα) and CXCR2 (IL-8Rβ) here instead. IL-9 Agonists: Interleukin 9 Antibodies: Enokizumab
Tocilizumab
Mammalian protein found in humans
elicits these effects by interacting with the cell surface chemokine receptor CXCR2. The gene for CXCL5 has four exons and is located on human chromosome 4
CXCL5
Chemical compound
Tocilizumab Levilimab IL-7 Agonists: Interleukin 7 IL-8 See CXCR1 (IL-8Rα) and CXCR2 (IL-8Rβ) here instead. IL-9 Agonists: Interleukin 9 Antibodies: Enokizumab
Anrukinzumab
Drugs to suppress IL-6 signalling
Tocilizumab Levilimab IL-7 Agonists: Interleukin 7 IL-8 See CXCR1 (IL-8Rα) and CXCR2 (IL-8Rβ) here instead. IL-9 Agonists: Interleukin 9 Antibodies: Enokizumab
Anti-interleukin-6
Pharmaceutical drug
Tocilizumab Levilimab IL-7 Agonists: Interleukin 7 IL-8 See CXCR1 (IL-8Rα) and CXCR2 (IL-8Rβ) here instead. IL-9 Agonists: Interleukin 9 Antibodies: Enokizumab
Anakinra
Protein found in humans
(GPCRs) CC CCR1 CCR2 CCRL2 CCR3 CCR4 CCR5 CCR6 CCR7 CCR8 CCR9 CCR10 CXC CXCR1 CXCR2 CXCR3 CXCR4 CXCR5 CXCR6 Other CX3C CX3CR1 XC XCR1 ACKR 1 2 3 4 5 CMKLR1
Atypical_chemokine_receptor_3
Monoclonal antibody medication
Tocilizumab Levilimab IL-7 Agonists: Interleukin 7 IL-8 See CXCR1 (IL-8Rα) and CXCR2 (IL-8Rβ) here instead. IL-9 Agonists: Interleukin 9 Antibodies: Enokizumab
Mepolizumab
Chemical compound
Xu L, Yao M (2020). "Liquiritin Alleviates Pain Through Inhibiting CXCL1/CXCR2 Signaling Pathway in Bone Cancer Pain Rat". Frontiers in Pharmacology. 11:
Liquiritin
7-transmembrane protein
Interleukin-8 Receptor, beta Identifiers Symbol IL8RB Alt. symbols CXCR2, CKR-2, CDw128b Other data Locus Chr. 2 q35
Interleukin-8_receptor
Protein-coding gene in the species Homo sapiens
Tocilizumab Levilimab IL-7 Agonists: Interleukin 7 IL-8 See CXCR1 (IL-8Rα) and CXCR2 (IL-8Rβ) here instead. IL-9 Agonists: Interleukin 9 Antibodies: Enokizumab
Interleukin_26
(GPCRs) CC CCR1 CCR2 CCRL2 CCR3 CCR4 CCR5 CCR6 CCR7 CCR8 CCR9 CCR10 CXC CXCR1 CXCR2 CXCR3 CXCR4 CXCR5 CXCR6 Other CX3C CX3CR1 XC XCR1 ACKR 1 2 3 4 5 CMKLR1
Lymphotoxin_beta_receptor
Monoclonal antibody against IL-17
Tocilizumab Levilimab IL-7 Agonists: Interleukin 7 IL-8 See CXCR1 (IL-8Rα) and CXCR2 (IL-8Rβ) here instead. IL-9 Agonists: Interleukin 9 Antibodies: Enokizumab
Secukinumab
Protein found in humans
(GPCRs) CC CCR1 CCR2 CCRL2 CCR3 CCR4 CCR5 CCR6 CCR7 CCR8 CCR9 CCR10 CXC CXCR1 CXCR2 CXCR3 CXCR4 CXCR5 CXCR6 Other CX3C CX3CR1 XC XCR1 ACKR 1 2 3 4 5 CMKLR1
Death_receptor_3
Protein found in humans
(GPCRs) CC CCR1 CCR2 CCRL2 CCR3 CCR4 CCR5 CCR6 CCR7 CCR8 CCR9 CCR10 CXC CXCR1 CXCR2 CXCR3 CXCR4 CXCR5 CXCR6 Other CX3C CX3CR1 XC XCR1 ACKR 1 2 3 4 5 CMKLR1
Decoy_receptor_3
Large protein superfamily of cell surface and soluble proteins
(GPCRs) CC CCR1 CCR2 CCRL2 CCR3 CCR4 CCR5 CCR6 CCR7 CCR8 CCR9 CCR10 CXC CXCR1 CXCR2 CXCR3 CXCR4 CXCR5 CXCR6 Other CX3C CX3CR1 XC XCR1 ACKR 1 2 3 4 5 CMKLR1
Immunoglobulin_superfamily
Drug given during chemotherapy to increase blood cell regeneration
Tocilizumab Levilimab IL-7 Agonists: Interleukin 7 IL-8 See CXCR1 (IL-8Rα) and CXCR2 (IL-8Rβ) here instead. IL-9 Agonists: Interleukin 9 Antibodies: Enokizumab
Promegapoietin
Medication used to treat autoimmune diseases
Tocilizumab Levilimab IL-7 Agonists: Interleukin 7 IL-8 See CXCR1 (IL-8Rα) and CXCR2 (IL-8Rβ) here instead. IL-9 Agonists: Interleukin 9 Antibodies: Enokizumab
Ixekizumab
Anti-inflammatory cytokine
Tocilizumab Levilimab IL-7 Agonists: Interleukin 7 IL-8 See CXCR1 (IL-8Rα) and CXCR2 (IL-8Rβ) here instead. IL-9 Agonists: Interleukin 9 Antibodies: Enokizumab
Interleukin_10
Mammalian protein found in humans
(CXCL8, GCP-1) Antagonists: Navarixin NAMs: Ladarixin Reparixin (repertaxin) CXCR2 (IL-8Rβ) Agonists: CXCL1 (MGSA) CXCL2 CXCL3 CXCL5 CXCL6 CXCL7 Emoctakin
CXCL9
Phenotype of senescent cells which secrete certain substances
MV, Augert A, Raguz S, et al. (June 2008). "Chemokine signaling via the CXCR2 receptor reinforces senescence". Cell. 133 (6): 1006–1018. doi:10.1016/j
Senescence-associated secretory phenotype
Senescence-associated_secretory_phenotype
Mammalian protein found in humans
Tocilizumab Levilimab IL-7 Agonists: Interleukin 7 IL-8 See CXCR1 (IL-8Rα) and CXCR2 (IL-8Rβ) here instead. IL-9 Agonists: Interleukin 9 Antibodies: Enokizumab
Interleukin_2
Immune system protein
(GPCRs) CC CCR1 CCR2 CCRL2 CCR3 CCR4 CCR5 CCR6 CCR7 CCR8 CCR9 CCR10 CXC CXCR1 CXCR2 CXCR3 CXCR4 CXCR5 CXCR6 Other CX3C CX3CR1 XC XCR1 ACKR 1 2 3 4 5 CMKLR1
CCR5
Heterodimeric cytokine acting as mediator of inflammation
Tocilizumab Levilimab IL-7 Agonists: Interleukin 7 IL-8 See CXCR1 (IL-8Rα) and CXCR2 (IL-8Rβ) here instead. IL-9 Agonists: Interleukin 9 Antibodies: Enokizumab
Interleukin_23
Protein that in humans is encoded by the IL33 gene
Tocilizumab Levilimab IL-7 Agonists: Interleukin 7 IL-8 See CXCR1 (IL-8Rα) and CXCR2 (IL-8Rβ) here instead. IL-9 Agonists: Interleukin 9 Antibodies: Enokizumab
Interleukin_33
Regulatory protein found in most eukaryotic tissues
(CXCL8, GCP-1) Antagonists: Navarixin NAMs: Ladarixin Reparixin (repertaxin) CXCR2 (IL-8Rβ) Agonists: CXCL1 (MGSA) CXCL2 CXCL3 CXCL5 CXCL6 CXCL7 Emoctakin
Ubiquitin
Mammalian protein found in humans
(CXCL8, GCP-1) Antagonists: Navarixin NAMs: Ladarixin Reparixin (repertaxin) CXCR2 (IL-8Rβ) Agonists: CXCL1 (MGSA) CXCL2 CXCL3 CXCL5 CXCL6 CXCL7 Emoctakin
CCL4
Q9H2A7 3818 CXCL17 HGNC:19232; Q6UXB2 3819 CXCR1 HGNC:6026; P25024 3820 CXCR2 HGNC:6027; P25025 3821 CXCR3 HGNC:4540; P49682 3822 CXCR4 HGNC:2561; P61073
List of human protein-coding genes 2
List_of_human_protein-coding_genes_2
Family of proteins
Interleukin-8 InterPro: IPR000174 (IL8R) IL8R-α (IL8RA, CXCR1) IL8R-β (IL8RB, CXCR2) Adrenomedullin receptor (GPR182) Duffy blood group, chemokine receptor
Rhodopsin-like_receptors
Protein encoding gene found in humans
responses by repertaxin, a new inhibitor of the chemokine receptors CXCR1 and CXCR2". Biochemical Pharmacology. 69 (3): 385–394. doi:10.1016/j.bcp.2004.10.007
CXCR1
Mammalian protein found in humans
target cell by interacting with a cell surface chemokine receptor called CXCR2. More recently, it has been shown that Cxcl3 regulates cell autonomously
CXCL3
2022). "Targeting T cell checkpoints 41BB and LAG3 and myeloid cell CXCR1/CXCR2 results in antitumor immunity and durable response in pancreatic cancer"
2022_in_science
Protein
(GPCRs) CC CCR1 CCR2 CCRL2 CCR3 CCR4 CCR5 CCR6 CCR7 CCR8 CCR9 CCR10 CXC CXCR1 CXCR2 CXCR3 CXCR4 CXCR5 CXCR6 Other CX3C CX3CR1 XC XCR1 ACKR 1 2 3 4 5 CMKLR1
CXCR4
Group of proteins
Tocilizumab Levilimab IL-7 Agonists: Interleukin 7 IL-8 See CXCR1 (IL-8Rα) and CXCR2 (IL-8Rβ) here instead. IL-9 Agonists: Interleukin 9 Antibodies: Enokizumab
Interleukin_17
Antiretroviral drug
(CXCL8, GCP-1) Antagonists: Navarixin NAMs: Ladarixin Reparixin (repertaxin) CXCR2 (IL-8Rβ) Agonists: CXCL1 (MGSA) CXCL2 CXCL3 CXCL5 CXCL6 CXCL7 Emoctakin
Maraviroc
Medical condition
by numerous inflammatory cytokines and neutrophilic attractants (such as CXCR2 receptor ligands). In this situation, mucociliary clearance is initiated
Allergic bronchopulmonary aspergillosis
Allergic_bronchopulmonary_aspergillosis
Protein involved in blood clotting, wound healing and inflammation
(CXCL8, GCP-1) Antagonists: Navarixin NAMs: Ladarixin Reparixin (repertaxin) CXCR2 (IL-8Rβ) Agonists: CXCL1 (MGSA) CXCL2 CXCL3 CXCL5 CXCL6 CXCL7 Emoctakin
Platelet_factor_4
Protein found in humans
(GPCRs) CC CCR1 CCR2 CCRL2 CCR3 CCR4 CCR5 CCR6 CCR7 CCR8 CCR9 CCR10 CXC CXCR1 CXCR2 CXCR3 CXCR4 CXCR5 CXCR6 Other CX3C CX3CR1 XC XCR1 ACKR 1 2 3 4 5 CMKLR1
Herpesvirus_entry_mediator
Protein-coding gene in humans
(GPCRs) CC CCR1 CCR2 CCRL2 CCR3 CCR4 CCR5 CCR6 CCR7 CCR8 CCR9 CCR10 CXC CXCR1 CXCR2 CXCR3 CXCR4 CXCR5 CXCR6 Other CX3C CX3CR1 XC XCR1 ACKR 1 2 3 4 5 CMKLR1
CXCR3
Protein-coding gene in humans
(CXCL8, GCP-1) Antagonists: Navarixin NAMs: Ladarixin Reparixin (repertaxin) CXCR2 (IL-8Rβ) Agonists: CXCL1 (MGSA) CXCL2 CXCL3 CXCL5 CXCL6 CXCL7 Emoctakin
C-C_motif_chemokine_ligand_24
Protein found in humans
Tocilizumab Levilimab IL-7 Agonists: Interleukin 7 IL-8 See CXCR1 (IL-8Rα) and CXCR2 (IL-8Rβ) here instead. IL-9 Agonists: Interleukin 9 Antibodies: Enokizumab
Interleukin 12 receptor, beta 2 subunit
Interleukin_12_receptor,_beta_2_subunit
Mammalian protein found in humans
(CXCL8, GCP-1) Antagonists: Navarixin NAMs: Ladarixin Reparixin (repertaxin) CXCR2 (IL-8Rβ) Agonists: CXCL1 (MGSA) CXCL2 CXCL3 CXCL5 CXCL6 CXCL7 Emoctakin
CXCL10
Protein-coding gene in the species Homo sapiens
(CXCL8, GCP-1) Antagonists: Navarixin NAMs: Ladarixin Reparixin (repertaxin) CXCR2 (IL-8Rβ) Agonists: CXCL1 (MGSA) CXCL2 CXCL3 CXCL5 CXCL6 CXCL7 Emoctakin
Macrophage migration inhibitory factor
Macrophage_migration_inhibitory_factor
Mammalian protein found in Mus musculus
Tocilizumab Levilimab IL-7 Agonists: Interleukin 7 IL-8 See CXCR1 (IL-8Rα) and CXCR2 (IL-8Rβ) here instead. IL-9 Agonists: Interleukin 9 Antibodies: Enokizumab
Interleukin_4
Monoclonal antibody
Tocilizumab Levilimab IL-7 Agonists: Interleukin 7 IL-8 See CXCR1 (IL-8Rα) and CXCR2 (IL-8Rβ) here instead. IL-9 Agonists: Interleukin 9 Antibodies: Enokizumab
Lebrikizumab
Protein found in humans
(GPCRs) CC CCR1 CCR2 CCRL2 CCR3 CCR4 CCR5 CCR6 CCR7 CCR8 CCR9 CCR10 CXC CXCR1 CXCR2 CXCR3 CXCR4 CXCR5 CXCR6 Other CX3C CX3CR1 XC XCR1 ACKR 1 2 3 4 5 CMKLR1
TNFRSF9
Chemical compound
(CXCL8, GCP-1) Antagonists: Navarixin NAMs: Ladarixin Reparixin (repertaxin) CXCR2 (IL-8Rβ) Agonists: CXCL1 (MGSA) CXCL2 CXCL3 CXCL5 CXCL6 CXCL7 Emoctakin
Plerixafor
Protein-coding gene in the species Homo sapiens
Tocilizumab Levilimab IL-7 Agonists: Interleukin 7 IL-8 See CXCR1 (IL-8Rα) and CXCR2 (IL-8Rβ) here instead. IL-9 Agonists: Interleukin 9 Antibodies: Enokizumab
Interleukin_1-alpha
Protein found in humans
(CXCL8, GCP-1) Antagonists: Navarixin NAMs: Ladarixin Reparixin (repertaxin) CXCR2 (IL-8Rβ) Agonists: CXCL1 (MGSA) CXCL2 CXCL3 CXCL5 CXCL6 CXCL7 Emoctakin
CCL2
Mammalian protein found in Homo sapiens
Tocilizumab Levilimab IL-7 Agonists: Interleukin 7 IL-8 See CXCR1 (IL-8Rα) and CXCR2 (IL-8Rβ) here instead. IL-9 Agonists: Interleukin 9 Antibodies: Enokizumab
Interleukin_23_subunit_alpha
Type I cytokine receptor
(GPCRs) CC CCR1 CCR2 CCRL2 CCR3 CCR4 CCR5 CCR6 CCR7 CCR8 CCR9 CCR10 CXC CXCR1 CXCR2 CXCR3 CXCR4 CXCR5 CXCR6 Other CX3C CX3CR1 XC XCR1 ACKR 1 2 3 4 5 CMKLR1
Interleukin-12_receptor
Growth factor secreted by stromal cells in the bone marrow and thymus
Tocilizumab Levilimab IL-7 Agonists: Interleukin 7 IL-8 See CXCR1 (IL-8Rα) and CXCR2 (IL-8Rβ) here instead. IL-9 Agonists: Interleukin 9 Antibodies: Enokizumab
Interleukin_7
Protein-coding gene in the species Homo sapiens
Tocilizumab Levilimab IL-7 Agonists: Interleukin 7 IL-8 See CXCR1 (IL-8Rα) and CXCR2 (IL-8Rβ) here instead. IL-9 Agonists: Interleukin 9 Antibodies: Enokizumab
Interleukin_11
Monoclonal antibody
Tocilizumab Levilimab IL-7 Agonists: Interleukin 7 IL-8 See CXCR1 (IL-8Rα) and CXCR2 (IL-8Rβ) here instead. IL-9 Agonists: Interleukin 9 Antibodies: Enokizumab
Tildrakizumab
Monoclonal antibody
Tocilizumab Levilimab IL-7 Agonists: Interleukin 7 IL-8 See CXCR1 (IL-8Rα) and CXCR2 (IL-8Rβ) here instead. IL-9 Agonists: Interleukin 9 Antibodies: Enokizumab
Benralizumab
Mammalian protein found in Homo sapiens
Tocilizumab Levilimab IL-7 Agonists: Interleukin 7 IL-8 See CXCR1 (IL-8Rα) and CXCR2 (IL-8Rβ) here instead. IL-9 Agonists: Interleukin 9 Antibodies: Enokizumab
Interleukin_1_beta
Type of receptor
(GPCRs) CC CCR1 CCR2 CCRL2 CCR3 CCR4 CCR5 CCR6 CCR7 CCR8 CCR9 CCR10 CXC CXCR1 CXCR2 CXCR3 CXCR4 CXCR5 CXCR6 Other CX3C CX3CR1 XC XCR1 ACKR 1 2 3 4 5 CMKLR1
Interleukin-20_receptor
Mammalian protein found in Homo sapiens
(CXCL8, GCP-1) Antagonists: Navarixin NAMs: Ladarixin Reparixin (repertaxin) CXCR2 (IL-8Rβ) Agonists: CXCL1 (MGSA) CXCL2 CXCL3 CXCL5 CXCL6 CXCL7 Emoctakin
Stromal_cell-derived_factor_1
Monoclonal antibody
Tocilizumab Levilimab IL-7 Agonists: Interleukin 7 IL-8 See CXCR1 (IL-8Rα) and CXCR2 (IL-8Rβ) here instead. IL-9 Agonists: Interleukin 9 Antibodies: Enokizumab
Pacibekitug
Investigational fatigue drugs
replacement Reparixin (DF-1681Y; Repertaxin) – CXC chemokine receptor CXCR1 and CXCR2 negative allosteric modulator Coacillium (LH-10; LH-4; LH-8) – various actions
List of investigational fatigue drugs
List_of_investigational_fatigue_drugs
Protein found in humans
(January 2001). "Identification of a motif in the carboxyl terminus of CXCR2 that is involved in adaptin 2 binding and receptor internalization". Biochemistry
Adaptor-related protein complex 2, alpha 1
Adaptor-related_protein_complex_2,_alpha_1
Protein-coding gene in humans
(GPCRs) CC CCR1 CCR2 CCRL2 CCR3 CCR4 CCR5 CCR6 CCR7 CCR8 CCR9 CCR10 CXC CXCR1 CXCR2 CXCR3 CXCR4 CXCR5 CXCR6 Other CX3C CX3CR1 XC XCR1 ACKR 1 2 3 4 5 CMKLR1
IL1RL1
Monoclonal antibody
Tocilizumab Levilimab IL-7 Agonists: Interleukin 7 IL-8 See CXCR1 (IL-8Rα) and CXCR2 (IL-8Rβ) here instead. IL-9 Agonists: Interleukin 9 Antibodies: Enokizumab
Fletikumab
Protein-coding gene in the species Homo sapiens
Tocilizumab Levilimab IL-7 Agonists: Interleukin 7 IL-8 See CXCR1 (IL-8Rα) and CXCR2 (IL-8Rβ) here instead. IL-9 Agonists: Interleukin 9 Antibodies: Enokizumab
Interleukin_9
Cell surface receptors specific for interleukin-5
(GPCRs) CC CCR1 CCR2 CCRL2 CCR3 CCR4 CCR5 CCR6 CCR7 CCR8 CCR9 CCR10 CXC CXCR1 CXCR2 CXCR3 CXCR4 CXCR5 CXCR6 Other CX3C CX3CR1 XC XCR1 ACKR 1 2 3 4 5 CMKLR1
Interleukin-5_receptor
Protein in the species Homo sapiens
Tocilizumab Levilimab IL-7 Agonists: Interleukin 7 IL-8 See CXCR1 (IL-8Rα) and CXCR2 (IL-8Rβ) here instead. IL-9 Agonists: Interleukin 9 Antibodies: Enokizumab
Interleukin_31
Group of cytokine proteins
Tocilizumab Levilimab IL-7 Agonists: Interleukin 7 IL-8 See CXCR1 (IL-8Rα) and CXCR2 (IL-8Rβ) here instead. IL-9 Agonists: Interleukin 9 Antibodies: Enokizumab
Interleukin-1_family
Monoclonal antibody
Tocilizumab Levilimab IL-7 Agonists: Interleukin 7 IL-8 See CXCR1 (IL-8Rα) and CXCR2 (IL-8Rβ) here instead. IL-9 Agonists: Interleukin 9 Antibodies: Enokizumab
Olokizumab
Type I cytokine receptor and coding gene in humans
(GPCRs) CC CCR1 CCR2 CCRL2 CCR3 CCR4 CCR5 CCR6 CCR7 CCR8 CCR9 CCR10 CXC CXCR1 CXCR2 CXCR3 CXCR4 CXCR5 CXCR6 Other CX3C CX3CR1 XC XCR1 ACKR 1 2 3 4 5 CMKLR1
Prolactin_receptor
Protein family
chemokine family, is named CXCL2 and acts through binding of CXCR1 and CXCR2. It is produced mainly by macrophages, monocytes and epithelial cells and
Macrophage inflammatory protein
Macrophage_inflammatory_protein
Protein-coding gene in the species Homo sapiens
(GPCRs) CC CCR1 CCR2 CCRL2 CCR3 CCR4 CCR5 CCR6 CCR7 CCR8 CCR9 CCR10 CXC CXCR1 CXCR2 CXCR3 CXCR4 CXCR5 CXCR6 Other CX3C CX3CR1 XC XCR1 ACKR 1 2 3 4 5 CMKLR1
C-C_chemokine_receptor_type_7
British cancer researcher
using mouse models they showed that inhibition of the chemokine receptor CXCR2 could suppress both colitis and spontaneous cancer. This was confirmed by
Owen_Sansom
Protein-coding gene in the species Homo sapiens
(GPCRs) CC CCR1 CCR2 CCRL2 CCR3 CCR4 CCR5 CCR6 CCR7 CCR8 CCR9 CCR10 CXC CXCR1 CXCR2 CXCR3 CXCR4 CXCR5 CXCR6 Other CX3C CX3CR1 XC XCR1 ACKR 1 2 3 4 5 CMKLR1
IFNAR1
Monoclonal antibody
Tocilizumab Levilimab IL-7 Agonists: Interleukin 7 IL-8 See CXCR1 (IL-8Rα) and CXCR2 (IL-8Rβ) here instead. IL-9 Agonists: Interleukin 9 Antibodies: Enokizumab
Guselkumab
travel, tourism, insurance
CXCR2
CXCR2
CXCR2
CXCR2
CXCR2
CXCR2
CXCR2
CXCR2
CXCR2
travel, tourism, insurance