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MEPOLIZUMAB

  • Mepolizumab
  • Monoclonal antibody medication

    Mepolizumab, sold under the brand name Nucala, is a humanized monoclonal antibody used for the treatment of severe eosinophilic asthma, eosinophilic granulomatosis

    Mepolizumab

    Mepolizumab

  • Eosinophilic granulomatosis with polyangiitis
  • Medical condition

    with polyangiitis. Patients taking mepolizumab experienced a "significant improvement" in their symptoms. Mepolizumab is a monoclonal antibody that targets

    Eosinophilic granulomatosis with polyangiitis

    Eosinophilic granulomatosis with polyangiitis

    Eosinophilic_granulomatosis_with_polyangiitis

  • Hypereosinophilic syndrome
  • Unexplained chronic eosinophila

    glucocorticoids such as prednisone. The addition of the monoclonal antibody mepolizumab may reduce the dose of glucocorticoids. Depending on eosinophil target-organ

    Hypereosinophilic syndrome

    Hypereosinophilic syndrome

    Hypereosinophilic_syndrome

  • Eosinophil
  • Type of white blood cells

    eosinophils in blood are rapidly reduced monoclonal antibody therapy – e.g., mepolizumab or reslizumab against IL-5, prevents eosinophilopoiesis, or benralizumab

    Eosinophil

    Eosinophil

    Eosinophil

  • Enteritis
  • Inflammation of the small intestine

    diets to avoid food allergies, azathioprine and antibodies, including mepolizumab, omalizumab, infliximab, and adalimumab. The word enteritis (/ˌɛntəˈraɪtɪs/)

    Enteritis

    Enteritis

    Enteritis

  • Depemokimab
  • Medication

    kappa). Depemokimab was developed by GSK. It is structurally similar to mepolizumab but contains seven amino acid substitutions in the heavy chain sequence

    Depemokimab

    Depemokimab

    Depemokimab

  • Dupilumab
  • Drug used to treat allergic diseases

    since 2019 to develop a high-dose subcutaneous formulation of dupilumab. Mepolizumab, anti–IL-5 to treat chronic rhinosinusitis with nasal polyps Omalizumab

    Dupilumab

    Dupilumab

    Dupilumab

  • Aspirin-exacerbated respiratory disease
  • Chronic inflammatory disease affecting the sinuses and lungs

    market in recent years have been used to treat AERD including dupilumab, mepolizumab, omalizumab, and benralizumab. Among treatment options, biologics have

    Aspirin-exacerbated respiratory disease

    Aspirin-exacerbated respiratory disease

    Aspirin-exacerbated_respiratory_disease

  • Eosinopenia
  • Medical condition

    in order to alleviate symptoms. Some examples of these drugs include mepolizumab, reslizumab, and benralizumab. Although eosinopenia has long been recognized

    Eosinopenia

    Eosinopenia

    Eosinopenia

  • Desensitization (medicine)
  • Medical intervention

    helminthic therapy; a drug to suppress toll-like receptor 9 (TLR9); and mepolizumab to treat eosinophilic esophagitis. Penicillin desensitization Castells

    Desensitization (medicine)

    Desensitization_(medicine)

  • List of GSK plc products
  • (naratriptan hydrochloride) Nimbex (cisatracurium besilate) Nucala (mepolizumab) Ojjaara (momelotinib) Otosporin ear drops (polymyxin B sulphate, neomycin

    List of GSK plc products

    List_of_GSK_plc_products

  • Type 2 inflammation
  • Pattern of immune response

    blockers: Altrakincept Pascolizumab IL-5-specific blockers: Benralizumab Mepolizumab Reslizumab IL-13-specific blockers: Lebrikizumab Tralokinumab Dual IL-4

    Type 2 inflammation

    Type_2_inflammation

  • Interleukin 5
  • Type of cytokine

    there are two FDA-approved monoclonal antibodies that inhibit IL-5, mepolizumab and reslizumab. Additionally, the antibody benralizumab blocks the interleukin-5

    Interleukin 5

    Interleukin 5

    Interleukin_5

  • Atopy
  • Predisposition towards allergy

    options with oral corticosteroids, biological treatments (e.g. omalizumab, mepolizumab) or allergen immunotherapy. Eczema Asthma Rhinitis Anaphylaxis Allergic

    Atopy

    Atopy

    Atopy

  • Interleukin 2
  • Mammalian protein found in humans

    Agonists: Interleukin 5 Antagonists: YM-90709 Antibodies: Benralizumab Mepolizumab Reslizumab Antisense oligonucleotides: TPI ASM8 IL-6 Agonists: Atexakin

    Interleukin 2

    Interleukin 2

    Interleukin_2

  • Interleukin 10
  • Anti-inflammatory cytokine

    Agonists: Interleukin 5 Antagonists: YM-90709 Antibodies: Benralizumab Mepolizumab Reslizumab Antisense oligonucleotides: TPI ASM8 IL-6 Agonists: Atexakin

    Interleukin 10

    Interleukin 10

    Interleukin_10

  • Functional endoscopic sinus surgery
  • Surgery to enlarge the paranasal sinus drainage pathways

    biologic agents targeting the type 2 inflammatory pathway — dupilumab, mepolizumab, omalizumab, and related monoclonal antibodies — for the treatment of

    Functional endoscopic sinus surgery

    Functional endoscopic sinus surgery

    Functional_endoscopic_sinus_surgery

  • Anti-asthmatic agent
  • Drug used to treat asthma

    Antibodies that aid in asthma symptomatic control include omalizumab, mepolizumab, reslizumab, benralizumab, dupilumab and tezepelumab. Omalizumab binds

    Anti-asthmatic agent

    Anti-asthmatic_agent

  • Interleukin-12 subunit beta
  • Protein-coding gene in the species Homo sapiens

    Agonists: Interleukin 5 Antagonists: YM-90709 Antibodies: Benralizumab Mepolizumab Reslizumab Antisense oligonucleotides: TPI ASM8 IL-6 Agonists: Atexakin

    Interleukin-12 subunit beta

    Interleukin-12 subunit beta

    Interleukin-12_subunit_beta

  • List of drugs: Mep–Mes
  • mepiroxol (INN) mepitiostane (INN) mepivacaine (INN) mepixanox (INN) mepolizumab (INN) mepramidil (INN) meprednisone (INN) Mepriam Mepro-Aspirin meprobamate

    List of drugs: Mep–Mes

    List_of_drugs:_Mep–Mes

  • Firestone Institute for Respiratory Health
  • Canadian health organization

    2009, Firestone researchers demonstrated that an experimental drug, mepolizumab can help reduce eosinophil production in sufferers of severe asthma.

    Firestone Institute for Respiratory Health

    Firestone_Institute_for_Respiratory_Health

  • Tezepelumab
  • Monoclonal antibody

    anti IL-4 antibody to treat chronic rhinosinusitis with nasal polyps mepolizumab, anti–IL-5 to treat chronic rhinosinusitis with nasal polyps omalizumab

    Tezepelumab

    Tezepelumab

    Tezepelumab

  • Theralizumab
  • Monoclonal antibody

    Inebilizumab Itolizumab Lampalizumab† Letolizumab Ligelizumab† Lulizumab pegol Mepolizumab Mogamulizumab Natalizumab Ocrelizumab (+hyaluronidase) Omalizumab Ozoralizumab

    Theralizumab

    Theralizumab

  • Ustekinumab
  • Biopharmaceutical drug

    Agonists: Interleukin 5 Antagonists: YM-90709 Antibodies: Benralizumab Mepolizumab Reslizumab Antisense oligonucleotides: TPI ASM8 IL-6 Agonists: Atexakin

    Ustekinumab

    Ustekinumab

  • Drug rash with eosinophilia and systemic symptoms
  • Rare reaction to certain medications

    T-cell activating cytokines including Il-5. The anti-IL-5 antibodies mepolizumab, reslizumab, and benralizumab have also been used to treat DRESS, and

    Drug rash with eosinophilia and systemic symptoms

    Drug_rash_with_eosinophilia_and_systemic_symptoms

  • Interleukin 7
  • Growth factor secreted by stromal cells in the bone marrow and thymus

    Agonists: Interleukin 5 Antagonists: YM-90709 Antibodies: Benralizumab Mepolizumab Reslizumab Antisense oligonucleotides: TPI ASM8 IL-6 Agonists: Atexakin

    Interleukin 7

    Interleukin 7

    Interleukin_7

  • Guselkumab
  • Monoclonal antibody

    Agonists: Interleukin 5 Antagonists: YM-90709 Antibodies: Benralizumab Mepolizumab Reslizumab Antisense oligonucleotides: TPI ASM8 IL-6 Agonists: Atexakin

    Guselkumab

    Guselkumab

    Guselkumab

  • Interleukin 1 beta
  • Mammalian protein found in Homo sapiens

    Agonists: Interleukin 5 Antagonists: YM-90709 Antibodies: Benralizumab Mepolizumab Reslizumab Antisense oligonucleotides: TPI ASM8 IL-6 Agonists: Atexakin

    Interleukin 1 beta

    Interleukin 1 beta

    Interleukin_1_beta

  • Secukinumab
  • Monoclonal antibody against IL-17

    Agonists: Interleukin 5 Antagonists: YM-90709 Antibodies: Benralizumab Mepolizumab Reslizumab Antisense oligonucleotides: TPI ASM8 IL-6 Agonists: Atexakin

    Secukinumab

    Secukinumab

    Secukinumab

  • Pacibekitug
  • Monoclonal antibody

    Agonists: Interleukin 5 Antagonists: YM-90709 Antibodies: Benralizumab Mepolizumab Reslizumab Antisense oligonucleotides: TPI ASM8 IL-6 Agonists: Atexakin

    Pacibekitug

    Pacibekitug

  • Eosinophilic myocarditis
  • Medical condition

    eosinophilic granulomatosis with polyangiitis can be successfully treated with mepolizumab. Idiopathic hypereosinophilic syndrome and lymphocyte-variant hypereosinophilia:

    Eosinophilic myocarditis

    Eosinophilic_myocarditis

  • Interleukin 40
  • Mammalian cytokine

    Agonists: Interleukin 5 Antagonists: YM-90709 Antibodies: Benralizumab Mepolizumab Reslizumab Antisense oligonucleotides: TPI ASM8 IL-6 Agonists: Atexakin

    Interleukin 40

    Interleukin 40

    Interleukin_40

  • Spartalizumab
  • Monoclonal antibody

    Inebilizumab Itolizumab Lampalizumab† Letolizumab Ligelizumab† Lulizumab pegol Mepolizumab Mogamulizumab Natalizumab Ocrelizumab (+hyaluronidase) Omalizumab Ozoralizumab

    Spartalizumab

    Spartalizumab

  • Anakinra
  • Pharmaceutical drug

    Agonists: Interleukin 5 Antagonists: YM-90709 Antibodies: Benralizumab Mepolizumab Reslizumab Antisense oligonucleotides: TPI ASM8 IL-6 Agonists: Atexakin

    Anakinra

    Anakinra

    Anakinra

  • CD4
  • Marker on immune cells

    Agonists: Interleukin 5 Antagonists: YM-90709 Antibodies: Benralizumab Mepolizumab Reslizumab Antisense oligonucleotides: TPI ASM8 IL-6 Agonists: Atexakin

    CD4

    CD4

    CD4

  • List of therapeutic monoclonal antibodies
  • Epidermal growth factor receptor (EGFR) colorectal, lung and stomach cancer Mepolizumab Nucala mab humanized IL-5 Y asthma and white blood cell diseases Metelimumab

    List of therapeutic monoclonal antibodies

    List of therapeutic monoclonal antibodies

    List_of_therapeutic_monoclonal_antibodies

  • Asthma-COPD overlap
  • Chronic inflammatory and obstructive disease of the lungs

    These monoclonal antibodies include omalizumab (an Anti-IgE antibody), mepolizumab (an anti-IL-5 antibody) and benralizumab (an anti-IL-5 receptor α antibody)

    Asthma-COPD overlap

    Asthma-COPD_overlap

  • Interleukin-1 receptor family
  • Immunoglobulin superfamily

    Agonists: Interleukin 5 Antagonists: YM-90709 Antibodies: Benralizumab Mepolizumab Reslizumab Antisense oligonucleotides: TPI ASM8 IL-6 Agonists: Atexakin

    Interleukin-1 receptor family

    Interleukin-1_receptor_family

  • Loeffler endocarditis
  • Medical condition

    eosinophilic granulomatosis with polyangiitis can be successfully treated with mepolizumab. Idiopathic hypereosinphilic syndrome and lymphocyte-variant hypereosinophilia:

    Loeffler endocarditis

    Loeffler_endocarditis

  • Olokizumab
  • Monoclonal antibody

    Agonists: Interleukin 5 Antagonists: YM-90709 Antibodies: Benralizumab Mepolizumab Reslizumab Antisense oligonucleotides: TPI ASM8 IL-6 Agonists: Atexakin

    Olokizumab

    Olokizumab

  • Interleukin 8 receptor, beta
  • Mammalian protein found in Homo sapiens

    Agonists: Interleukin 5 Antagonists: YM-90709 Antibodies: Benralizumab Mepolizumab Reslizumab Antisense oligonucleotides: TPI ASM8 IL-6 Agonists: Atexakin

    Interleukin 8 receptor, beta

    Interleukin 8 receptor, beta

    Interleukin_8_receptor,_beta

  • Interleukin-12 receptor
  • Type I cytokine receptor

    Agonists: Interleukin 5 Antagonists: YM-90709 Antibodies: Benralizumab Mepolizumab Reslizumab Antisense oligonucleotides: TPI ASM8 IL-6 Agonists: Atexakin

    Interleukin-12 receptor

    Interleukin-12_receptor

  • IL31RA
  • Protein-coding gene in the species Homo sapiens

    Agonists: Interleukin 5 Antagonists: YM-90709 Antibodies: Benralizumab Mepolizumab Reslizumab Antisense oligonucleotides: TPI ASM8 IL-6 Agonists: Atexakin

    IL31RA

    IL31RA

    IL31RA

  • ST2 cardiac biomarker
  • Member of the interleukin 1 receptor family

    Agonists: Interleukin 5 Antagonists: YM-90709 Antibodies: Benralizumab Mepolizumab Reslizumab Antisense oligonucleotides: TPI ASM8 IL-6 Agonists: Atexakin

    ST2 cardiac biomarker

    ST2_cardiac_biomarker

  • IL36G
  • Protein-coding gene in the species Homo sapiens

    Agonists: Interleukin 5 Antagonists: YM-90709 Antibodies: Benralizumab Mepolizumab Reslizumab Antisense oligonucleotides: TPI ASM8 IL-6 Agonists: Atexakin

    IL36G

    IL36G

    IL36G

  • Pascolizumab
  • Monoclonal antibody

    Agonists: Interleukin 5 Antagonists: YM-90709 Antibodies: Benralizumab Mepolizumab Reslizumab Antisense oligonucleotides: TPI ASM8 IL-6 Agonists: Atexakin

    Pascolizumab

    Pascolizumab

  • Interleukin-20 receptor
  • Type of receptor

    Agonists: Interleukin 5 Antagonists: YM-90709 Antibodies: Benralizumab Mepolizumab Reslizumab Antisense oligonucleotides: TPI ASM8 IL-6 Agonists: Atexakin

    Interleukin-20 receptor

    Interleukin-20_receptor

  • Tocilizumab
  • Immunosuppressive drug

    Agonists: Interleukin 5 Antagonists: YM-90709 Antibodies: Benralizumab Mepolizumab Reslizumab Antisense oligonucleotides: TPI ASM8 IL-6 Agonists: Atexakin

    Tocilizumab

    Tocilizumab

  • Interleukin 12
  • Interleukin

    Agonists: Interleukin 5 Antagonists: YM-90709 Antibodies: Benralizumab Mepolizumab Reslizumab Antisense oligonucleotides: TPI ASM8 IL-6 Agonists: Atexakin

    Interleukin 12

    Interleukin 12

    Interleukin_12

  • Interleukin 27 receptor, alpha subunit
  • Protein-coding gene in the species Homo sapiens

    Agonists: Interleukin 5 Antagonists: YM-90709 Antibodies: Benralizumab Mepolizumab Reslizumab Antisense oligonucleotides: TPI ASM8 IL-6 Agonists: Atexakin

    Interleukin 27 receptor, alpha subunit

    Interleukin 27 receptor, alpha subunit

    Interleukin_27_receptor,_alpha_subunit

  • Interleukin-5 receptor
  • Cell surface receptors specific for interleukin-5

    antibodies are available to target IL-5R. Benralizumab binds to IL-5Ra, while mepolizumab and reslizumab bind to IL-5, preventing it from binding to IL-5Ra. Takatsu

    Interleukin-5 receptor

    Interleukin-5_receptor

  • Interleukin 15 receptor, alpha subunit
  • Protein-coding gene in the species Homo sapiens

    Agonists: Interleukin 5 Antagonists: YM-90709 Antibodies: Benralizumab Mepolizumab Reslizumab Antisense oligonucleotides: TPI ASM8 IL-6 Agonists: Atexakin

    Interleukin 15 receptor, alpha subunit

    Interleukin 15 receptor, alpha subunit

    Interleukin_15_receptor,_alpha_subunit

  • Canakinumab
  • Pharmaceutical drug

    Agonists: Interleukin 5 Antagonists: YM-90709 Antibodies: Benralizumab Mepolizumab Reslizumab Antisense oligonucleotides: TPI ASM8 IL-6 Agonists: Atexakin

    Canakinumab

    Canakinumab

    Canakinumab

  • Lymphocyte-variant hypereosinophilia
  • Medical condition

    substitutes include interferon-α or its analog, peginterferon alfa-2a, mepolizumab (an antibody directed against IL-5), ciclosporin (an immunosuppressive

    Lymphocyte-variant hypereosinophilia

    Lymphocyte-variant_hypereosinophilia

  • Outline of immunology
  • Overview of and topical guide to immunology

    Secukinumab Siltuximab Sirukumab Spesolimab Tocilizumab Interleukin 5 Mepolizumab Immunoglobulin E Omalizumab Interferon Faralimomab IL-6 Elsilimomab IL-12

    Outline of immunology

    Outline_of_immunology

  • Interleukin 11 receptor alpha subunit
  • Protein-coding gene in the species Homo sapiens

    Agonists: Interleukin 5 Antagonists: YM-90709 Antibodies: Benralizumab Mepolizumab Reslizumab Antisense oligonucleotides: TPI ASM8 IL-6 Agonists: Atexakin

    Interleukin 11 receptor alpha subunit

    Interleukin 11 receptor alpha subunit

    Interleukin_11_receptor_alpha_subunit

  • Interleukin-8 receptor
  • 7-transmembrane protein

    Agonists: Interleukin 5 Antagonists: YM-90709 Antibodies: Benralizumab Mepolizumab Reslizumab Antisense oligonucleotides: TPI ASM8 IL-6 Agonists: Atexakin

    Interleukin-8 receptor

    Interleukin-8_receptor

  • Interleukin 5 receptor alpha subunit
  • Protein-coding gene in the species Homo sapiens

    Protein unc-119 homolog, and SDCBP Cluster of differentiation Benralizumab Mepolizumab Reslizumab GRCh38: Ensembl release 89: ENSG00000091181 – Ensembl, May

    Interleukin 5 receptor alpha subunit

    Interleukin 5 receptor alpha subunit

    Interleukin_5_receptor_alpha_subunit

  • Interleukin 22
  • Protein, encoded in humans by IL22 gene

    Agonists: Interleukin 5 Antagonists: YM-90709 Antibodies: Benralizumab Mepolizumab Reslizumab Antisense oligonucleotides: TPI ASM8 IL-6 Agonists: Atexakin

    Interleukin 22

    Interleukin 22

    Interleukin_22

  • Interleukin 6
  • Cytokine protein

    Agonists: Interleukin 5 Antagonists: YM-90709 Antibodies: Benralizumab Mepolizumab Reslizumab Antisense oligonucleotides: TPI ASM8 IL-6 Agonists: Atexakin

    Interleukin 6

    Interleukin 6

    Interleukin_6

  • Interleukin-1 family
  • Group of cytokine proteins

    Agonists: Interleukin 5 Antagonists: YM-90709 Antibodies: Benralizumab Mepolizumab Reslizumab Antisense oligonucleotides: TPI ASM8 IL-6 Agonists: Atexakin

    Interleukin-1 family

    Interleukin-1 family

    Interleukin-1_family

  • IL-2 receptor
  • Lymphocyte receptor specific for Interleukin-2

    Agonists: Interleukin 5 Antagonists: YM-90709 Antibodies: Benralizumab Mepolizumab Reslizumab Antisense oligonucleotides: TPI ASM8 IL-6 Agonists: Atexakin

    IL-2 receptor

    IL-2 receptor

    IL-2_receptor

  • Interleukin-15 receptor
  • Protein complex

    Agonists: Interleukin 5 Antagonists: YM-90709 Antibodies: Benralizumab Mepolizumab Reslizumab Antisense oligonucleotides: TPI ASM8 IL-6 Agonists: Atexakin

    Interleukin-15 receptor

    Interleukin-15 receptor

    Interleukin-15_receptor

  • Basiliximab
  • Pharmaceutical drug

    Agonists: Interleukin 5 Antagonists: YM-90709 Antibodies: Benralizumab Mepolizumab Reslizumab Antisense oligonucleotides: TPI ASM8 IL-6 Agonists: Atexakin

    Basiliximab

    Basiliximab

  • Interleukin 8
  • Mammalian protein found in humans

    Agonists: Interleukin 5 Antagonists: YM-90709 Antibodies: Benralizumab Mepolizumab Reslizumab Antisense oligonucleotides: TPI ASM8 IL-6 Agonists: Atexakin

    Interleukin 8

    Interleukin 8

    Interleukin_8

  • Interleukin 1-alpha
  • Protein-coding gene in the species Homo sapiens

    Agonists: Interleukin 5 Antagonists: YM-90709 Antibodies: Benralizumab Mepolizumab Reslizumab Antisense oligonucleotides: TPI ASM8 IL-6 Agonists: Atexakin

    Interleukin 1-alpha

    Interleukin 1-alpha

    Interleukin_1-alpha

  • Interleukin-22 receptor
  • Transmembrane protein found in humans

    Agonists: Interleukin 5 Antagonists: YM-90709 Antibodies: Benralizumab Mepolizumab Reslizumab Antisense oligonucleotides: TPI ASM8 IL-6 Agonists: Atexakin

    Interleukin-22 receptor

    Interleukin-22_receptor

  • Lebrikizumab
  • Monoclonal antibody

    Agonists: Interleukin 5 Antagonists: YM-90709 Antibodies: Benralizumab Mepolizumab Reslizumab Antisense oligonucleotides: TPI ASM8 IL-6 Agonists: Atexakin

    Lebrikizumab

    Lebrikizumab

    Lebrikizumab

  • Anti-interleukin-6
  • Drugs to suppress IL-6 signalling

    Agonists: Interleukin 5 Antagonists: YM-90709 Antibodies: Benralizumab Mepolizumab Reslizumab Antisense oligonucleotides: TPI ASM8 IL-6 Agonists: Atexakin

    Anti-interleukin-6

    Anti-interleukin-6

  • Gleich's syndrome
  • Medical condition

    treatments used in eosinophil-related disorders have been tried, but mepolizumab (which blocks the interleukin 5 receptor) was not as effective as had

    Gleich's syndrome

    Gleich's_syndrome

  • Interleukin 25
  • Cytokine that belongs to the IL-17 cytokine family

    Agonists: Interleukin 5 Antagonists: YM-90709 Antibodies: Benralizumab Mepolizumab Reslizumab Antisense oligonucleotides: TPI ASM8 IL-6 Agonists: Atexakin

    Interleukin 25

    Interleukin 25

    Interleukin_25

  • Interleukin-6 receptor
  • Protein found in humans

    Agonists: Interleukin 5 Antagonists: YM-90709 Antibodies: Benralizumab Mepolizumab Reslizumab Antisense oligonucleotides: TPI ASM8 IL-6 Agonists: Atexakin

    Interleukin-6 receptor

    Interleukin-6 receptor

    Interleukin-6_receptor

  • Interleukin 13
  • Protein and coding gene in humans

    Agonists: Interleukin 5 Antagonists: YM-90709 Antibodies: Benralizumab Mepolizumab Reslizumab Antisense oligonucleotides: TPI ASM8 IL-6 Agonists: Atexakin

    Interleukin 13

    Interleukin 13

    Interleukin_13

  • Interleukin 4
  • Mammalian protein found in Mus musculus

    Agonists: Interleukin 5 Antagonists: YM-90709 Antibodies: Benralizumab Mepolizumab Reslizumab Antisense oligonucleotides: TPI ASM8 IL-6 Agonists: Atexakin

    Interleukin 4

    Interleukin 4

    Interleukin_4

  • Interleukin 20
  • Protein found in humans

    Agonists: Interleukin 5 Antagonists: YM-90709 Antibodies: Benralizumab Mepolizumab Reslizumab Antisense oligonucleotides: TPI ASM8 IL-6 Agonists: Atexakin

    Interleukin 20

    Interleukin 20

    Interleukin_20

  • Interleukin 23
  • Heterodimeric cytokine acting as mediator of inflammation

    Agonists: Interleukin 5 Antagonists: YM-90709 Antibodies: Benralizumab Mepolizumab Reslizumab Antisense oligonucleotides: TPI ASM8 IL-6 Agonists: Atexakin

    Interleukin 23

    Interleukin 23

    Interleukin_23

  • Inolimomab
  • Monoclonal antibody

    Agonists: Interleukin 5 Antagonists: YM-90709 Antibodies: Benralizumab Mepolizumab Reslizumab Antisense oligonucleotides: TPI ASM8 IL-6 Agonists: Atexakin

    Inolimomab

    Inolimomab

  • Common gamma chain
  • Protein-coding gene in humans

    Agonists: Interleukin 5 Antagonists: YM-90709 Antibodies: Benralizumab Mepolizumab Reslizumab Antisense oligonucleotides: TPI ASM8 IL-6 Agonists: Atexakin

    Common gamma chain

    Common gamma chain

    Common_gamma_chain

  • Monoclonal antibody therapy
  • Form of immunotherapy

    human Tissue factor pathway inhibitor hemophilia A and B 761369 Link mepolizumab Nucala GlaxoSmithKline 11/4/2015 subcutaneous humanized IL-5 severe asthma

    Monoclonal antibody therapy

    Monoclonal antibody therapy

    Monoclonal_antibody_therapy

  • IL2RA
  • Mammalian protein found in Homo sapiens

    Agonists: Interleukin 5 Antagonists: YM-90709 Antibodies: Benralizumab Mepolizumab Reslizumab Antisense oligonucleotides: TPI ASM8 IL-6 Agonists: Atexakin

    IL2RA

    IL2RA

    IL2RA

  • Interleukin-17A
  • Protein-coding gene in the species Homo sapiens

    Agonists: Interleukin 5 Antagonists: YM-90709 Antibodies: Benralizumab Mepolizumab Reslizumab Antisense oligonucleotides: TPI ASM8 IL-6 Agonists: Atexakin

    Interleukin-17A

    Interleukin-17A

    Interleukin-17A

  • Tucotuzumab celmoleukin
  • Monoclonal antibody drug

    Agonists: Interleukin 5 Antagonists: YM-90709 Antibodies: Benralizumab Mepolizumab Reslizumab Antisense oligonucleotides: TPI ASM8 IL-6 Agonists: Atexakin

    Tucotuzumab celmoleukin

    Tucotuzumab_celmoleukin

  • Interleukin
  • Group of cytokines

    Agonists: Interleukin 5 Antagonists: YM-90709 Antibodies: Benralizumab Mepolizumab Reslizumab Antisense oligonucleotides: TPI ASM8 IL-6 Agonists: Atexakin

    Interleukin

    Interleukin

  • Interleukin 15
  • Cytokine with structural similarity to Interleukin-2

    Agonists: Interleukin 5 Antagonists: YM-90709 Antibodies: Benralizumab Mepolizumab Reslizumab Antisense oligonucleotides: TPI ASM8 IL-6 Agonists: Atexakin

    Interleukin 15

    Interleukin 15

    Interleukin_15

  • Ixekizumab
  • Medication used to treat autoimmune diseases

    Agonists: Interleukin 5 Antagonists: YM-90709 Antibodies: Benralizumab Mepolizumab Reslizumab Antisense oligonucleotides: TPI ASM8 IL-6 Agonists: Atexakin

    Ixekizumab

    Ixekizumab

  • Interleukin-10 receptor
  • Cell surface receptor for interleukin-10

    Agonists: Interleukin 5 Antagonists: YM-90709 Antibodies: Benralizumab Mepolizumab Reslizumab Antisense oligonucleotides: TPI ASM8 IL-6 Agonists: Atexakin

    Interleukin-10 receptor

    Interleukin-10_receptor

  • Interferon lambda receptor 1
  • Protein found in humans

    Agonists: Interleukin 5 Antagonists: YM-90709 Antibodies: Benralizumab Mepolizumab Reslizumab Antisense oligonucleotides: TPI ASM8 IL-6 Agonists: Atexakin

    Interferon lambda receptor 1

    Interferon lambda receptor 1

    Interferon_lambda_receptor_1

  • Clonal hypereosinophilia
  • Group of blood-based disorders

    Bagnasco D, Ferrando M, Puggioni F, Passalacqua G, Canonica GW (2017). "Mepolizumab in the management of severe eosinophilic asthma in adults: current evidence

    Clonal hypereosinophilia

    Clonal_hypereosinophilia

  • IL1RAP
  • Protein-coding gene in the species Homo sapiens

    Agonists: Interleukin 5 Antagonists: YM-90709 Antibodies: Benralizumab Mepolizumab Reslizumab Antisense oligonucleotides: TPI ASM8 IL-6 Agonists: Atexakin

    IL1RAP

    IL1RAP

    IL1RAP

  • Daclizumab
  • Pharmaceutical drug

    Agonists: Interleukin 5 Antagonists: YM-90709 Antibodies: Benralizumab Mepolizumab Reslizumab Antisense oligonucleotides: TPI ASM8 IL-6 Agonists: Atexakin

    Daclizumab

    Daclizumab

  • Interleukin-3 receptor
  • Mammalian protein found in Homo sapiens

    Agonists: Interleukin 5 Antagonists: YM-90709 Antibodies: Benralizumab Mepolizumab Reslizumab Antisense oligonucleotides: TPI ASM8 IL-6 Agonists: Atexakin

    Interleukin-3 receptor

    Interleukin-3 receptor

    Interleukin-3_receptor

  • Denileukin diftitox
  • Pharmaceutical drug

    Agonists: Interleukin 5 Antagonists: YM-90709 Antibodies: Benralizumab Mepolizumab Reslizumab Antisense oligonucleotides: TPI ASM8 IL-6 Agonists: Atexakin

    Denileukin diftitox

    Denileukin_diftitox

  • Interleukin-11 receptor
  • Type I cytokine receptor

    Agonists: Interleukin 5 Antagonists: YM-90709 Antibodies: Benralizumab Mepolizumab Reslizumab Antisense oligonucleotides: TPI ASM8 IL-6 Agonists: Atexakin

    Interleukin-11 receptor

    Interleukin-11_receptor

  • ATC code R03
  • Pharmaceutical drug classification

    Omalizumab R03DX06 Seratrodast R03DX07 Roflumilast R03DX08 Reslizumab R03DX09 Mepolizumab R03DX10 Benralizumab R03DX11 Tezepelumab R03DX12 Depemokimab "ATC (Anatomical

    ATC code R03

    ATC_code_R03

  • Interleukin 17
  • Group of proteins

    Agonists: Interleukin 5 Antagonists: YM-90709 Antibodies: Benralizumab Mepolizumab Reslizumab Antisense oligonucleotides: TPI ASM8 IL-6 Agonists: Atexakin

    Interleukin 17

    Interleukin 17

    Interleukin_17

  • Interleukin 33
  • Protein that in humans is encoded by the IL33 gene

    Agonists: Interleukin 5 Antagonists: YM-90709 Antibodies: Benralizumab Mepolizumab Reslizumab Antisense oligonucleotides: TPI ASM8 IL-6 Agonists: Atexakin

    Interleukin 33

    Interleukin 33

    Interleukin_33

  • Interferon type III
  • Group of anti-viral cytokines

    Agonists: Interleukin 5 Antagonists: YM-90709 Antibodies: Benralizumab Mepolizumab Reslizumab Antisense oligonucleotides: TPI ASM8 IL-6 Agonists: Atexakin

    Interferon type III

    Interferon_type_III

  • Glycoprotein 130
  • Mammalian protein found in Homo sapiens

    Agonists: Interleukin 5 Antagonists: YM-90709 Antibodies: Benralizumab Mepolizumab Reslizumab Antisense oligonucleotides: TPI ASM8 IL-6 Agonists: Atexakin

    Glycoprotein 130

    Glycoprotein 130

    Glycoprotein_130

  • Oprelvekin
  • Pharmaceutical drug

    Agonists: Interleukin 5 Antagonists: YM-90709 Antibodies: Benralizumab Mepolizumab Reslizumab Antisense oligonucleotides: TPI ASM8 IL-6 Agonists: Atexakin

    Oprelvekin

    Oprelvekin

  • Reslizumab
  • Pharmaceutical drug

    Agonists: Interleukin 5 Antagonists: YM-90709 Antibodies: Benralizumab Mepolizumab Reslizumab Antisense oligonucleotides: TPI ASM8 IL-6 Agonists: Atexakin

    Reslizumab

    Reslizumab

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