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Protein
(cluster of differentiation 184) is a protein that in humans is encoded by the CXCR4 gene. The protein is a CXC chemokine receptor. CXCR-4 is an alpha-chemokine
CXCR4
A CXCR4 antagonist is a substance which blocks the CXCR4 receptor and prevent its activation. Blocking the receptor stops the receptor's ligand, CXCL12
CXCR4_antagonist
Human retrovirus, cause of AIDS
receptor, CXCR4, for entry. Dual-tropic HIV-1 strains are thought to be transitional strains of HIV-1 and thus are able to use both CCR5 and CXCR4 as co-receptors
HIV
targets for drug therapy, one of them being the viral entry pathway. CCR5 and CXCR4 are the main receptors involved in the HIV entry process. These receptors
CCR5_receptor_antagonist
Protein family
has three highly related ligands in mammals, CXCL9, CXCL10 and CXCL11. CXCR4 (also known as fusin) is the receptor for a chemokine known as CXCL12 (or
CXC_chemokine_receptors
Medical condition
from autosomal dominant mutations in the gene for the chemokine receptor, CXCR4, resulting in a carboxy-terminus truncation of the receptor of between 10
WHIM_syndrome
Chemical compound
partial agonist) of the alpha chemokine receptor CXCR4 and an allosteric agonist of CXCR7. The CXCR4 alpha-chemokine receptor and one of its ligands,
Plerixafor
Immune system protein
forms a short α-helix unique to CCR5 compared to related receptors like CXCR4. The overall architecture, including the arrangement of helices and loops
CCR5
Mammalian protein found in Homo sapiens
marrow through a CXCR4 dependent mechanism. CXCR4, previously called LESTR or fusin, is the receptor for CXCL12. This CXCL12-CXCR4 interaction used to
Stromal_cell-derived_factor_1
Cell type in which HIV infects and replicates
alpha-chemokine receptor, CXCR4, for entry. These strains are now called X4 viruses. The alpha-chemokine SDF-1, a ligand for CXCR4, suppresses replication
HIV_tropism
Type of blood cancer
mutation in MYD88 (90% of patients) and a somatic mutation in CXCR4 (27% of patients). CXCR4 mutations cause symptomatic hyperviscosity syndrome and high
Waldenström_macroglobulinemia
Mammalian protein found in humans
animal studies. ACKR3 and CXCR4 have been shown to interact, different possibilities regarding the involvement of ACKR3 and CXCR4 in CXCL12 signaling: A)
ACKR3
Chemical compound
Mohammed; et al. (31 August 2022). "Mavorixafor, an Orally Bioavailable CXCR4 Antagonist, Increases Immune Cell Infiltration and Inflammatory Status of
Mavorixafor
Medical condition
myelokathexis. A gain-of-function mutation resulting in a truncated form of CXCR4 is believed to be its cause. The truncated form of the receptor has a 2-fold
Myelokathexis
tissues and cell types. The primary retention signal is orchestrated by CXCR4, expressed on the HSC surface, and CXCL12, which is secreted at high concentrations
Hematopoietic stem cell mobilization
Hematopoietic_stem_cell_mobilization
HGNC:6026; P25024 3820 CXCR2 HGNC:6027; P25025 3821 CXCR3 HGNC:4540; P49682 3822 CXCR4 HGNC:2561; P61073 3823 CXCR5 HGNC:1060; P32302 3824 CXCR6 HGNC:16647; O00574
List of human protein-coding genes 2
List_of_human_protein-coding_genes_2
Cell type
expression + + + VEGFR2 (KDR/Flk1) expression + + ++ TIE-2 expression + + + CXCR4 expression + + +/- von Willebrand factor expression +/- +/- + ALDH Bright
Endothelial_progenitor_cell
Medication
multiple myeloma. Motixafortide is a hematopoietic stem cell mobilizer and a CXCR4 antagonist. It is given by subcutaneous injection. The most common side
Motixafortide
Antiretroviral drug
macrophages and T cells. Because HIV can also use other coreceptors, such as CXCR4, an HIV tropism test such as a trofile assay must be performed to determine
Maraviroc
Monoclonal antibody
designed for the treatment of hematologic malignancies. Ulocuplumab targets CXCR4. This drug was developed by Bristol-Myers Squibb. World Health Organization
Ulocuplumab
Semi-solid tissue in the spongy portions of bones
Wang J, Liu X, Lu H, Jiang C, Cui X, Yu L, Fu X, Li Q, Wang J (2015). "CXCR4(+)CD45(-) BMMNC subpopulation is superior to unfractionated BMMNCs for protection
Bone_marrow
Protein found in humans
receptor CXCR4-mediated signaling and receptor internalization, and this implicates multiple interaction sites between beta-arrestin and CXCR4". The Journal
Arrestin_beta_2
Protein-coding gene in humans
minor coreceptor for HIV-1, nearly all strains of which use CCR5 and/or CXCR4. Most SIV strains can use CXCR6 and recent evidence suggests that in monkeys
CXCR6
Chemical compound
(against CXCL10) CXCR4 Agonists: MIF SDF-1 (CXCL12) Ubiquitin Antagonists: Mavorixafor Plerixafor (AMD3100) Antibodies: Ulocuplumab (against CXCR4) CXCR5 Agonists:
Bertilimumab
Protein-coding gene in humans
CCRL2 CCR3 CCR4 CCR5 CCR6 CCR7 CCR8 CCR9 CCR10 CXC IL-8 CXCR1 CXCR2 CXCR3 CXCR4 CXCR5 CXCR6 CXCR7 Other CX3C CX3CR1 XC XCR1 CCBP2 CMKLR1 TNF receptor 1-10
CCR10
Type of cell surface receptor
An important member of the CCR family is CCR5 (and its near-homologue CXCR4), which acts as the primary co-receptor for HIV viral infection. The HIV
Co-receptor
Species of virus
relationship between HHV-7 and HIV-1 co-receptors CXCR4 and CCR5. During infection, HHV-7 causes a loss of CXCR4 in CD4+ T-cells in addition to lowering intracellular
Human_herpesvirus_7
Protein-coding gene in the species Homo sapiens
CCRL2 CCR3 CCR4 CCR5 CCR6 CCR7 CCR8 CCR9 CCR10 CXC IL-8 CXCR1 CXCR2 CXCR3 CXCR4 CXCR5 CXCR6 CXCR7 Other CX3C CX3CR1 XC XCR1 CCBP2 CMKLR1 TNF receptor 1-10
Herpesvirus_entry_mediator
Monoclonal antibody
(against CXCL10) CXCR4 Agonists: MIF SDF-1 (CXCL12) Ubiquitin Antagonists: Mavorixafor Plerixafor (AMD3100) Antibodies: Ulocuplumab (against CXCR4) CXCR5 Agonists:
Eldelumab
Infection specificity of pathogens
along with the CD4-gp120 complex to enter the target cells - either CCR5 or CXCR4. This demonstrates an example of how cell surface receptors can affect the
Host_tropism
Receptors on the surface of cells
CCRL2 CCR3 CCR4 CCR5 CCR6 CCR7 CCR8 CCR9 CCR10 CXC IL-8 CXCR1 CXCR2 CXCR3 CXCR4 CXCR5 CXCR6 CXCR7 Other CX3C CX3CR1 XC XCR1 CCBP2 CMKLR1 TNF receptor 1-10
Type_I_cytokine_receptor
Protein-coding gene in humans
binding of adenosine deaminase to CD26 by a mechanism modulated by CD4 and CXCR4 expression". FEBS Letters. 477 (1–2): 123–8. Bibcode:2000FEBSL.477..123B
ADARB1
Mammalian protein found in humans
(against CXCL10) CXCR4 Agonists: MIF SDF-1 (CXCL12) Ubiquitin Antagonists: Mavorixafor Plerixafor (AMD3100) Antibodies: Ulocuplumab (against CXCR4) CXCR5 Agonists:
CCL1
Pharmacologic characteristic
traditional balanced antagonist, a biased antagonist of the chemokine receptor CXCR4 that blocks G protein signaling while allowing beta-arrestin recruitment
Functional_selectivity
Mammalian protein found in humans
(against CXCL10) CXCR4 Agonists: MIF SDF-1 (CXCL12) Ubiquitin Antagonists: Mavorixafor Plerixafor (AMD3100) Antibodies: Ulocuplumab (against CXCR4) CXCR5 Agonists:
Interleukin_8
Protein in humans
(against CXCL10) CXCR4 Agonists: MIF SDF-1 (CXCL12) Ubiquitin Antagonists: Mavorixafor Plerixafor (AMD3100) Antibodies: Ulocuplumab (against CXCR4) CXCR5 Agonists:
CCR1
Protein-coding gene in the species Homo sapiens
CCRL2 CCR3 CCR4 CCR5 CCR6 CCR7 CCR8 CCR9 CCR10 CXC IL-8 CXCR1 CXCR2 CXCR3 CXCR4 CXCR5 CXCR6 CXCR7 Other CX3C CX3CR1 XC XCR1 CCBP2 CMKLR1 TNF receptor 1-10
Decoy_receptor_1
Protein-coding gene in the species Homo sapiens
CCRL2 CCR3 CCR4 CCR5 CCR6 CCR7 CCR8 CCR9 CCR10 CXC IL-8 CXCR1 CXCR2 CXCR3 CXCR4 CXCR5 CXCR6 CXCR7 Other CX3C CX3CR1 XC XCR1 CCBP2 CMKLR1 TNF receptor 1-10
IL1RL2
Protein family
"bystander" T cells, assisting in progression toward AIDS. By antagonizing the CXCR4 receptor, Tat also appears to selectively encourage the reproduction of
Tat_(HIV)
Mammalian protein found in humans
(against CXCL10) CXCR4 Agonists: MIF SDF-1 (CXCL12) Ubiquitin Antagonists: Mavorixafor Plerixafor (AMD3100) Antibodies: Ulocuplumab (against CXCR4) CXCR5 Agonists:
CCL19
2004). "Germinal center dark and light zone organization is mediated by CXCR4 and CXCR5". Nature Immunology. 5 (9): 943–952. doi:10.1038/ni1100. PMID 15300245
Jason_Cyster
Protein-coding gene in the species Homo sapiens
inhibitory factor has been reported to interact with: BNIPL, CD74, COPS5, CXCR4, and RPS19. MIF is a potential drug target for sepsis, rheumatoid arthritis
Macrophage migration inhibitory factor
Macrophage_migration_inhibitory_factor
Muscular degenerative disease of the face, shoulder blades, and upper arms
hypothesized that retinopathy is due to DUX4-protein-induced modulation of the CXCR4–SDF1 axis, which has a role in endothelial tip cell morphology and vascular
Facioscapulohumeral muscular dystrophy
Facioscapulohumeral_muscular_dystrophy
Protein-coding gene in the species Homo sapiens
Freedman BD, Collman RG (Nov 2003). "Macrophage activation through CCR5- and CXCR4-mediated gp120-elicited signaling pathways". Journal of Leukocyte Biology
PIK3C2B
Monoclonal antibody
a post-attachment inhibitor, blocking HIV from binding to the CCR5 and CXCR4 co-receptors after HIV binds to the CD4 receptor on the surface of a CD4
Ibalizumab
Type of cancer
is 25–30%. Retrospective research showed that two chemokine receptors, CXCR4 and CXCR7, can be used as molecular prognosis factors. People who express
Ewing_sarcoma
Protein family
CCRL2 CCR3 CCR4 CCR5 CCR6 CCR7 CCR8 CCR9 CCR10 CXC IL-8 CXCR1 CXCR2 CXCR3 CXCR4 CXCR5 CXCR6 CXCR7 Other CX3C CX3CR1 XC XCR1 CCBP2 CMKLR1 TNF receptor 1-10
CD120
Protein-coding gene in the species Homo sapiens
QH, Tomkowicz B, et al. (2004). "Macrophage activation through CCR5- and CXCR4-mediated gp120-elicited signaling pathways". J. Leukoc. Biol. 74 (5): 676–82
PIK3CB
Cancerous tumour in a bone
pathological factors such as the degree of P-glycoprotein, whether the tumor is CXCR4-positive, or HER2-positive are also important, as these are associated with
Osteosarcoma
Protein-coding gene in the species Homo sapiens
CCRL2 CCR3 CCR4 CCR5 CCR6 CCR7 CCR8 CCR9 CCR10 CXC IL-8 CXCR1 CXCR2 CXCR3 CXCR4 CXCR5 CXCR6 CXCR7 Other CX3C CX3CR1 XC XCR1 CCBP2 CMKLR1 TNF receptor 1-10
Interleukin 10 receptor, beta subunit
Interleukin_10_receptor,_beta_subunit
Medical condition
well as its pattern of inheritance. WHIM syndrome, caused by a mutation in CXCR4, is associated with similar chronic cutaneous viral infections. Treatment
DOCK8_deficiency
Chemical compound
the bones. Gambogic acid inhibits such osteoclastogenesis by inhibiting CXCR4 signaling pathways. Gambogic acid has also been found to bind to transferrin
Gambogic_acid
Protein-coding gene in the species Homo sapiens
CCRL2 CCR3 CCR4 CCR5 CCR6 CCR7 CCR8 CCR9 CCR10 CXC IL-8 CXCR1 CXCR2 CXCR3 CXCR4 CXCR5 CXCR6 CXCR7 Other CX3C CX3CR1 XC XCR1 CCBP2 CMKLR1 TNF receptor 1-10
TNFRSF19
target an alternative co-receptor such as CXCR4.[citation needed] Ibalizumab is effective against both CCR5 and CXCR4 tropic HIV viruses. In rare cases, individuals
Management_of_HIV/AIDS
Class of protein complexes
living organism with regulatory implication. The crystal structure of the CXCR4 dimer was published in 2010. GPCR oligomers consist of receptor dimers,
GPCR_oligomer
Medication used in cancer treatment
the expression of CD20 (target of rituximab/ofatumumab) by targeting the CXCR4/SDF1 axis. Together, these data are consistent with a mechanistic model
Ibrutinib
Cytokine receptor which binds interleukin 1
CCRL2 CCR3 CCR4 CCR5 CCR6 CCR7 CCR8 CCR9 CCR10 CXC IL-8 CXCR1 CXCR2 CXCR3 CXCR4 CXCR5 CXCR6 CXCR7 Other CX3C CX3CR1 XC XCR1 CCBP2 CMKLR1 TNF receptor 1-10
Interleukin-1_receptor
Mammalian protein found in humans
(against CXCL10) CXCR4 Agonists: MIF SDF-1 (CXCL12) Ubiquitin Antagonists: Mavorixafor Plerixafor (AMD3100) Antibodies: Ulocuplumab (against CXCR4) CXCR5 Agonists:
CCR2
Mammalian protein found in humans
(against CXCL10) CXCR4 Agonists: MIF SDF-1 (CXCL12) Ubiquitin Antagonists: Mavorixafor Plerixafor (AMD3100) Antibodies: Ulocuplumab (against CXCR4) CXCR5 Agonists:
CXCL16
Mammalian protein found in humans
Schröttner P, Schraufstätter I, Burger M (November 2010). "Attenuation of CXCR4 responses by CCL18 in acute lymphocytic leukemia B cells". J. Cell. Physiol
CCL18
Medical condition
induces cardiomyocyte apoptosis either by signalling through CCR3, CCR5 or CXCR4, by entry into cardiomyocytes (after binding to ganglioside GM1), or through
HIV-associated_cardiomyopathy
Mammalian protein found in humans
(against CXCL10) CXCR4 Agonists: MIF SDF-1 (CXCL12) Ubiquitin Antagonists: Mavorixafor Plerixafor (AMD3100) Antibodies: Ulocuplumab (against CXCR4) CXCR5 Agonists:
CXCL6
Type of CRISPR tool
activated target CXCR4 gene in K562 cell lines. Comparing with the dCas9-VP64 activation complex, they were able to increase the CXCR4 gene expression
CRISPR_activation
Mammalian protein found in humans
(against CXCL10) CXCR4 Agonists: MIF SDF-1 (CXCL12) Ubiquitin Antagonists: Mavorixafor Plerixafor (AMD3100) Antibodies: Ulocuplumab (against CXCR4) CXCR5 Agonists:
CCL17
Species of virus
not entirely certain. A few studies have proposed MHC class II, CD4 and CXCR4 proteins as possible receptors however, none of these proteins have been
Visna-maedi_virus
Protein-coding gene in the species Homo sapiens
immortalized with Epstein-Barr virus upregulate CCR6 and CCR10 and downregulate CXCR4 and CXCR5". Journal of Virology. 76 (6): 3072–3077. doi:10.1128/JVI.76.6
C-C_chemokine_receptor_type_7
Biological process
correlation with lymph node metastasis, poor prognosis, and regulation of CXCR4 expression". BMC Cancer. 9 (1): 220. doi:10.1186/1471-2407-9-220. ISSN 1471-2407
Vascular remodelling in the embryo
Vascular_remodelling_in_the_embryo
German patients cured of HIV
this is a small minority of viruses that use alternate receptors, such as CXCR4 or CCR2. Those individuals who are homozygous for the CCR5 mutation are
Berlin_Patient
Medication used for epilepsy, bipolar disorder and migraine
(May 2010). "The histone deacetylase inhibitor ITF2357 decreases surface CXCR4 and CCR5 expression on CD4(+) T-cells and monocytes and is superior to valproic
Valproate
Protein-coding gene in humans
CCRL2 CCR3 CCR4 CCR5 CCR6 CCR7 CCR8 CCR9 CCR10 CXC IL-8 CXCR1 CXCR2 CXCR3 CXCR4 CXCR5 CXCR6 CXCR7 Other CX3C CX3CR1 XC XCR1 CCBP2 CMKLR1 TNF receptor 1-10
C-C motif chemokine receptor 8
C-C_motif_chemokine_receptor_8
Protein-coding gene in humans
CCRL2 CCR3 CCR4 CCR5 CCR6 CCR7 CCR8 CCR9 CCR10 CXC IL-8 CXCR1 CXCR2 CXCR3 CXCR4 CXCR5 CXCR6 CXCR7 Other CX3C CX3CR1 XC XCR1 CCBP2 CMKLR1 TNF receptor 1-10
Granulocyte-macrophage colony-stimulating factor receptor
Granulocyte-macrophage_colony-stimulating_factor_receptor
Biological term
between the chemokine CXCL12 expressed by stromal cells and its receptor CXCR4 expressed on HSCs has been proposed as one mechanism. In addition, the cytokine-receptor
Hematopoietic_stem_cell_niche
Mammalian protein found in Homo sapiens
CCRL2 CCR3 CCR4 CCR5 CCR6 CCR7 CCR8 CCR9 CCR10 CXC IL-8 CXCR1 CXCR2 CXCR3 CXCR4 CXCR5 CXCR6 CXCR7 Other CX3C CX3CR1 XC XCR1 CCBP2 CMKLR1 TNF receptor 1-10
BAFF_receptor
Species of bacterium
binding with matrix proteins and interaction with CXC-chemokine receptor 4 (CXCR4). Loss of function experiments have confirmed that P. gingivalis mutants
Porphyromonas_gingivalis
Protein-coding gene in humans
chemokines activate ion channels in primary macrophages through CCR5 and CXCR4 stimulation". Proc. Natl. Acad. Sci. U.S.A. 97 (9): 4832–7. Bibcode:2000PNAS
KCNMB4
Field of study
methylation and positively with histone acetylation in mouse microsome extracts. CXCR4 is a protein that acts as a coreceptor for the entry of HIV. It has been
Pharmacoepigenetics
Protein-coding gene in humans
Ghinassi B, D'Amore E, Jimeno J, Vannucchi AM, Migliaccio AR (November 2010). "CXCR4-independent rescue of the myeloproliferative defect of the Gata1low myelofibrosis
GATA1
Field of immunology research
progresses. HIV binds to immune cell surface receptors, including CD 4 and CXCR4 or CD4 and CCR5. The binding causes conformation changes and results in
HIV/AIDS_research
Protein of the immune system
Zhang L, Qiao A, Watson K, Zhang J, Fan GH (February 2008). "Activation of CXCR4 triggers ubiquitination and down-regulation of major histocompatibility
MHC_class_I
Human disease
caused by a gain-of-function mutation of the chemokine receptor CXCR4. The mutation in CXCR4 increases signaling because it disrupts negative regulatory elements
Hypogammaglobulinemia
Protein-coding gene in the species Homo sapiens
isoforms, have been characterized. USP14 has been shown to interact with CXCR4. IU1 and related compounds VLX1570 (non selective inhibitor of proteasome
USP14
Membrane receptor protein found in humans
CCRL2 CCR3 CCR4 CCR5 CCR6 CCR7 CCR8 CCR9 CCR10 CXC IL-8 CXCR1 CXCR2 CXCR3 CXCR4 CXCR5 CXCR6 CXCR7 Other CX3C CX3CR1 XC XCR1 CCBP2 CMKLR1 TNF receptor 1-10
Tumor necrosis factor receptor 2
Tumor_necrosis_factor_receptor_2
Mammalian protein found in humans
(against CXCL10) CXCR4 Agonists: MIF SDF-1 (CXCL12) Ubiquitin Antagonists: Mavorixafor Plerixafor (AMD3100) Antibodies: Ulocuplumab (against CXCR4) CXCR5 Agonists:
CXCL10
that use the CCR5 receptor, the TNPO3 mutation causing LGMD1F blocks the CXCR4 receptor, making it effective on different HIV-1 strains, due to HIV tropism
Innate_resistance_to_HIV
American neurobiologist
B-Lymphopoiesis, Myelopoiesis, and Derailed Cerebellar Neuron Migration in CXCR4- and SDF-1-Deficient Mice". Proceedings of the National Academy of Sciences
Rosalind_A._Segal
Protein-coding gene in the species Homo sapiens
CCRL2 CCR3 CCR4 CCR5 CCR6 CCR7 CCR8 CCR9 CCR10 CXC IL-8 CXCR1 CXCR2 CXCR3 CXCR4 CXCR5 CXCR6 CXCR7 Other CX3C CX3CR1 XC XCR1 CCBP2 CMKLR1 TNF receptor 1-10
IFNAR2
Protein-coding gene in the species Homo sapiens
CCRL2 CCR3 CCR4 CCR5 CCR6 CCR7 CCR8 CCR9 CCR10 CXC IL-8 CXCR1 CXCR2 CXCR3 CXCR4 CXCR5 CXCR6 CXCR7 Other CX3C CX3CR1 XC XCR1 CCBP2 CMKLR1 TNF receptor 1-10
Interleukin 10 receptor, alpha subunit
Interleukin_10_receptor,_alpha_subunit
Protein-coding gene in humans
chemokines activate ion channels in primary macrophages through CCR5 and CXCR4 stimulation". Proc. Natl. Acad. Sci. U.S.A. 97 (9): 4832–7. Bibcode:2000PNAS
CLCA4
Antibiotic
downstream from NF-κB activation leading to decreased chemokine receptor CXCR4 signaling causing reduced inflammation. Despite the efficiency of treating
Azithromycin
Large protein superfamily of cell surface and soluble proteins
CCRL2 CCR3 CCR4 CCR5 CCR6 CCR7 CCR8 CCR9 CCR10 CXC IL-8 CXCR1 CXCR2 CXCR3 CXCR4 CXCR5 CXCR6 CXCR7 Other CX3C CX3CR1 XC XCR1 CCBP2 CMKLR1 TNF receptor 1-10
Immunoglobulin_superfamily
Protein-coding gene in the species Homo sapiens
CCRL2 CCR3 CCR4 CCR5 CCR6 CCR7 CCR8 CCR9 CCR10 CXC IL-8 CXCR1 CXCR2 CXCR3 CXCR4 CXCR5 CXCR6 CXCR7 Other CX3C CX3CR1 XC XCR1 CCBP2 CMKLR1 TNF receptor 1-10
Oncostatin_M_receptor
Mammalian protein found in humans
(against CXCL10) CXCR4 Agonists: MIF SDF-1 (CXCL12) Ubiquitin Antagonists: Mavorixafor Plerixafor (AMD3100) Antibodies: Ulocuplumab (against CXCR4) CXCR5 Agonists:
CCL21
Chemical compound
site on gp120. All strains of HIV-1 use one of two coreceptors: CCR5 or CXCR4; coreceptor specificity will be described below. Once gp120 binds to the
Vicriviroc
How an animal develops its sexual-reproduction cells
their target sites.[citation needed] In zebrafish, the PGCs express two CXCR4 transmembrane receptor proteins. The signaling system involving this protein
Germline_development
Medical condition
contain the L265P mutation in the MYD88 (>90% of cases) and a mutation in the CXCR4 gene (30% of cases). Patients with this lymphoma commonly have an IgM gammaopathy
Monoclonal B-cell lymphocytosis
Monoclonal_B-cell_lymphocytosis
Cell that guides radial neuronal migration
control tangential migration of hem-derived Cajal-Retzius cells via CXCL12/CXCR4 signaling". Nature Neuroscience. 9 (10): 1284–93. doi:10.1038/nn1764. PMID 16964252
Cajal–Retzius_cell
Protein-coding gene in the species Homo sapiens
CCRL2 CCR3 CCR4 CCR5 CCR6 CCR7 CCR8 CCR9 CCR10 CXC IL-8 CXCR1 CXCR2 CXCR3 CXCR4 CXCR5 CXCR6 CXCR7 Other CX3C CX3CR1 XC XCR1 CCBP2 CMKLR1 TNF receptor 1-10
Interleukin-7_receptor-α
Cluster of cells surrounding an oocyte
lower oocyte competence or worse pregnancy outcomes include: BDNF, CCND2, CXCR4, GPX3, HSPB1, DVL3, DHCR7, CTNND1, TRIM28, STAR, AREG, CX43, PTGS2, SCD1
Cumulus_oophorus
Protein-coding gene in humans
CCRL2 CCR3 CCR4 CCR5 CCR6 CCR7 CCR8 CCR9 CCR10 CXC IL-8 CXCR1 CXCR2 CXCR3 CXCR4 CXCR5 CXCR6 CXCR7 Other CX3C CX3CR1 XC XCR1 CCBP2 CMKLR1 TNF receptor 1-10
CCRL2
Protein found in humans
CCRL2 CCR3 CCR4 CCR5 CCR6 CCR7 CCR8 CCR9 CCR10 CXC IL-8 CXCR1 CXCR2 CXCR3 CXCR4 CXCR5 CXCR6 CXCR7 Other CX3C CX3CR1 XC XCR1 CCBP2 CMKLR1 TNF receptor 1-10
Death_receptor_6
CXCR4
CXCR4
CXCR4
CXCR4
Girl/Female
Tamil
Padma Priya | பதà¯à®®à®ªà¯à®°à®¿à®¯à®¾
Lover of lotus
Girl/Female
English American
Healer.
Boy/Male
Bengali, Indian
Development; Brightness
Biblical
house; blindness
Girl/Female
Arabic, Muslim
Golden Morning; Beautiful Morning
Girl/Female
French
Little angel.
Surname or Lastname
English
English : variant of Alsbury.
Male
Irish
Irish and Scottish Gaelic name SUIBHNE means "well-going."Â
Surname or Lastname
English (of Norman origin)
English (of Norman origin) : from a derivative of the Continental Germanic personal name Maginhari, composed of the elements magin ‘strength’, ‘might’ + hari ‘army’.
Female
English
English name derived from the name of the gem, "topaz," the birthstone for the month of November. Pliny says that the topaz was named for an island where the yellow stone was mined, either in the Red Sea or the Arabian Sea. The word was derived from Latin topazus, from Greek topazos/topazion, which is of obscure origin, but there may be a connection with the Sanskrit word tapas, TOPAZ means "heat; fire."
CXCR4
CXCR4
CXCR4
CXCR4
CXCR4