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Complex segregation analysis (CSA) is a technique within genetic epidemiology to determine whether there is evidence that a major gene underlies the distribution
Complex_segregation_analysis
Topics referred to by the same term
assessment Chief Scientific Adviser (disambiguation), several uses Complex segregation analysis, in genetic epidemiology Chemical Shift Anisotropy, the orientation
CSA
Biological process
opposite poles, a process facilitated by a protein complex referred to as cohesin. Upon proper segregation, a complete set of chromatids ends up in each of
Chromosome_segregation
Animal with hearing difficulty
Cargill, Edward J; Strain, George M (2007). "Heritability and complex segregation analysis of deafness in Jack Russell Terriers". BMC Veterinary Research
Deaf_animal
Racial segregation in the United States is the legally and/or socially enforced separation of black people from white people, as well as the de facto
Racial segregation in the United States
Racial_segregation_in_the_United_States
Distribution of workers across and within occupations
gender. More types of occupational segregation include racial and ethnicity segregation, and sexual orientation segregation. These demographic characteristics
Occupational_segregation
Term in molecular biology
profiles are then examined so that a segregation table may be formed. Segregation tables are the foundation of GAM analysis. They contain information detailing
Genome_architecture_mapping
Model of auditory perception
differences classically shown to promote segregation are those of frequency (for pure tones), fundamental frequency (for complex tones), frequency composition,
Auditory_scene_analysis
Racial separation in schools
admitted white students. Segregation was enforced by laws in U.S. states, primarily in the Southern United States, although segregation could also occur in
School segregation in the United States
School_segregation_in_the_United_States
Race or ethnic separation in daily life
Racial segregation is the separation of people into racial or other ethnic groups in daily life. Segregation can involve the spatial separation of the
Racial_segregation
Enrichment of atoms, ions, and molecules
science, segregation is the enrichment of atoms, ions, or molecules at a microscopic region in a materials system. While the terms segregation and adsorption
Segregation (materials science)
Segregation_(materials_science)
Laws enforcing racial segregation in the U.S.
from the late 19th century to the mid-20th century that enforced racial segregation. The origin of the term Jim Crow is obscure, but probably refers to a
Jim_Crow_laws
Separation of people according to their religion
Religious segregation is the separation of people according to their religion. The term has been applied to cases of religious-based segregation which occurs
Religious_segregation
Transmission of multiple close together genes
van Houwelingen, Hans C (29 June 2009). "A simple method for co-segregation analysis to evaluate the pathogenicity of unclassified variants; BRCA1 and
Cosegregation
American economist (1921–2016)
University of Maryland, College Park. He was also co-faculty at the New England Complex Systems Institute. Schelling was awarded the 2005 Nobel Memorial Prize
Thomas_Schelling
Protein found in humans
chromosome segregation. CENPL contributes to maintaining conditions required for accurate chromosome segregation through its role in the CENP-L/N complex and
Centromere_protein_L
Computational auditory scene analysis (CASA) is the study of auditory scene analysis by computational means. In essence, CASA systems are "machine listening"
Computational auditory scene analysis
Computational_auditory_scene_analysis
Research centre
public bikes schemes such as the London's cycle hire scheme, population segregation in large cities as well as climate change in the London region. The centre
UCL Centre for Advanced Spatial Analysis
UCL_Centre_for_Advanced_Spatial_Analysis
South African system of racial segregation
"separateness", lit. 'aparthood') was a system of institutionalised racial segregation that existed in South Africa from 1948 to 1994. It also existed in South
Apartheid
Israeli system of racial segregation and discrimination
Israeli apartheid is a system of institutionalized segregation and discrimination in the Israeli-occupied Palestinian territories. The system is characterized
Israeli_apartheid
conserved molecular mechanism for plasmid partitioning and chromosome segregation in bacteria. Originally identified as a genetic element required for
ParABS_system
Attempt to racially diversify American public schools
Court landmark decision in Brown v. Board of Education declared racial segregation in public schools unconstitutional, many American schools continued to
Desegregation_busing
Protein complex
Condensins are large protein complexes that play a central role in chromosome condensation and segregation during mitosis and meiosis (Figure 1). Their
Condensin
Social structure made up of a set of social actors
Network Analysis and Mining. 6 51. doi:10.1007/s13278-016-0358-5. S2CID 18520393. Bojanowski, Michał; Corten, Rense (2014-10-01). "Measuring segregation in
Social_network
Extremely large or complex datasets
Big data primarily refers to data sets that are too large or complex to be dealt with by traditional data-processing software. Data with many entries
Big_data
American aviation regulatory document
AC 25.1309–1 is an FAA Advisory Circular (AC) (Subject: System Design and Analysis) that identifies acceptable means for showing compliance with the airworthiness
AC_25.1309-1
chromatid exchanges in the parental cell prior to segregation, the assessment of non-random segregation of sister chromatids, the identification of misoriented
Single-cell DNA template strand sequencing
Single-cell_DNA_template_strand_sequencing
Cell cycle checkpoint
named chromosome segregation. To ensure that chromosome segregation takes place correctly, cells have developed a precise and complex mechanism. In the
Spindle_checkpoint
Advocacy for separation from a larger group
discourse settings equate separatism with religious segregation, racial segregation, or sex segregation, while other discourse settings take the broader
Separatism
Description of phase separation
also indicates segregation into domains is the asymptotic outcome of the evolution of this equation. In real experiments, the segregation of an initially
Cahn–Hilliard_equation
Country primarily in North America
in the South to remain unchecked, sundown towns in the Midwest, and segregation in communities across the country, which would be reinforced in part
United_States
2016 film by Theodore Melfi
composite characters, and dramatized or invented incidents depicting segregation at Langley, and some argued it featured a white savior narrative. The
Hidden_Figures
Protein complex that allows microtubules to attach to chromosomes during cell division
chromatids remain associated by cohesin complexes until anaphase, when chromosome segregation occurs. If chromosome segregation happens correctly, each daughter
Kinetochore
Protein-coding gene in humans
correct segregation of chromosomes during cell division. The cohesin multiprotein complex is required for sister chromatid cohesion. This complex is composed
SMC1A
Protein-coding gene in the species Homo sapiens
T, et al. (2006). "The human Mis12 complex is required for kinetochore assembly and proper chromosome segregation". J. Cell Biol. 173 (1): 9–17. doi:10
DSN1
Protein-coding gene in the species Homo sapiens
T, et al. (2006). "The human Mis12 complex is required for kinetochore assembly and proper chromosome segregation". J. Cell Biol. 173 (1): 9–17. doi:10
MIS12
Protein-coding gene in humans
condensin I and II, large protein complexes involved in high order chromosome organization, including condensation and segregation. SMC-4 protein is commonly
SMC4
Protein-coding gene in humans
"Proteomics analysis of the centromere complex from HeLa interphase cells: UV-damaged DNA binding protein 1 (DDB-1) is a component of the CEN-complex, while
Centromere_protein_U
Canadian cognitive psychologist (1936–2023)
Jersey: Lawrence Erlbaum. Bregman, A.S. (1993). Auditory scene analysis: Listening in complex environments. In S.E. McAdams, and E. Bigand (Eds.) Thinking
Albert_Bregman
Fourth stage of mitosis and meiosis
anaphase, to help chromosome segregation and the re-formation of the nucleus. Anaphase starts when the anaphase promoting complex marks an inhibitory chaperone
Anaphase
Init system for Unix-like computer operating systems
Parallel service startup (off by default) Dependency-based boot-up Process segregation through cgroups Per-service resource limits (ulimit) Separation of code
OpenRC
Protein-coding gene in the species Homo sapiens
and chromosome maturation. The SMC-5/6 complex in mouse oocytes is essential for the formation of segregation competent bivalents during meiosis. In the
SMC6
Software development process
actual software system that will manage it. Command Query Responsibility Segregation (CQRS) is an architectural pattern for separating reading data (a 'query')
Domain-driven_design
Solitary Confinement In The US
Taylor. 2004. Federally Sentenced Women in Administrative Segregation: A Descriptive Analysis. Research Report No. R-158. Ottawa: Research Branch, Correctional
Solitary confinement of women in the United States
Solitary_confinement_of_women_in_the_United_States
Protein-coding gene in humans
between MLH1 and either PMS3 or MLH3 can substitute for PMS2. This protein complex formed between the 2 sets of heterodimers enables initiation of repair
MLH1
Class of enzymes
family of cytoskeletal motor proteins (though they are actually protein complexes) that move along microtubules in cells. They convert the chemical energy
Dynein
Protein found in humans
This interaction has been implicated in the coordination of chromosome segregation with cell division in yeast. GRCh38: Ensembl release 89: ENSG00000149503
Inner_centromere_protein
Protein-coding gene in the species Homo sapiens
the WAPL gene (previously WAPAL). WAPL is a key regulator of the Cohesin complex which mediates sister chromatid cohesion, homologous recombination and
Wings apart-like protein homolog
Wings_apart-like_protein_homolog
Field of study
encompasses the study of systemic racism, like residential segregation and other complex social processes between different racial and ethnic groups
Sociology of race and ethnic relations
Sociology_of_race_and_ethnic_relations
Data scientist, AI specialist (b. April 1980)
industry; traits such as gender, sex, race, or social class hold potential segregation that may result in unfair decisions. META strived to avoid this by making
Rumman_Chowdhury
Concept in ecology
population sizes. Niche segregation: The random selection of niches in largely empty niche space will often automatically lead to segregation (this mechanism
Ecological_niche
Short story by Flannery O'Connor
concerned about how blacks and whites could live together in a post-segregation world. In a 1963 interview with C. Ross Mullins for Jubilee magazine
Everything That Rises Must Converge (short story)
Everything_That_Rises_Must_Converge_(short_story)
Mammalian protein found in humans
believed to have roles in sister-kinetochore coorientation and chromosome segregation during meiosis I. PLK1 functions during meiotic centrosome biogenesis
PLK1
American singer-songwriter (born 2005)
2026). "D4vd Transferred To L.A. County Men's Central Jail, Placed In Segregation". TMZ. Retrieved April 21, 2026. Horowitz, Steven J. (April 23, 2026)
D4vd
Aspect of population genetics
that linkage is less likely. Computerised LOD score analysis is a simple way to analyse complex family pedigrees in order to determine the linkage between
Genetic_linkage
Protein-coding gene in humans
(previously SOGA1). This microtubule protein is involved in chromosome segregation. It has also been known as SOGA family member 1 or suppressor of glucose
MTCL2
Social stratification conferring status
cagots des Pyrénées: une ségrégation attestée, une mobilité mal connue" [The cagots of the Pyrenees: an attested segregation, a poorly known mobility]
Caste
school administrators. Within the residential schools, there was no segregation of sick students from healthy students, and students infected with deadly
Analysis of European colonialism and colonization
Analysis_of_European_colonialism_and_colonization
short, their "findings indicate that residential segregation matters" as "African[-]American segregation was negatively associated with the availability
Physician shortage in the United States
Physician_shortage_in_the_United_States
Failure to separate properly during cell division
the SAC may contribute to maternal age-related errors in segregation control. The cohesin complex is responsible for keeping together sister chromatids and
Nondisjunction
Race or ethnic-based discrimination
include associated social aspects such as nativism, xenophobia, otherness, segregation, hierarchical ranking, and supremacism. While the concepts of race and
Racism
1918 scientific article by Ronald Fisher
Laura; Blangero, John (1 May 2010). "Variance Component Methods for Analysis of Complex Phenotypes". Cold Spring Harbor Protocols. 2010 (5) pdb.top77. doi:10
The Correlation between Relatives on the Supposition of Mendelian Inheritance
The_Correlation_between_Relatives_on_the_Supposition_of_Mendelian_Inheritance
Gender identity of lacking a gender
to the legally recognised as agender.[clarification needed] In 2017, an analysis of gender identity surveys found that 14% of transgender participants identified
Agender
Protein-coding gene in the species Homo sapiens
Zomerdijk JC, Mann M, Lamond AI (December 2000). "Functional analysis of the human CDC5L complex and identification of its components by mass spectrometry"
TOP2A
Vector quantization algorithm minimizing the sum of squared deviations
where clustered regions correspond to domains of interaction or co-segregation, providing insight into the regulatory organization of the genome. In
K-means_clustering
German plant geneticist (1900–1975)
9:1-16 Michaelis, P (1971) The investigation of plasmone segregation by the pattern-analysis. Nucleus 10: 1-14 "Michaelis, Peter | Encyclopedia.com".
Peter_Michaelis
Protein-coding gene in the species Homo sapiens
integrity of a multiprotein complex named cohesin. This protective system is essential for faithful chromosome segregation during mitosis and meiosis,
Shugoshin_2
A.; Chavajay, P. (2010). "Children's Integration in Communities and Segregation From People of Differing Ages". Perspectives on Psychological Science
Indigenous peoples of the Americas
Indigenous_peoples_of_the_Americas
Multivalued function in mathematics
= w e w {\displaystyle f(w)=we^{w}} , where w {\displaystyle w} is any complex number and e w {\displaystyle e^{w}} is the exponential function. The function
Lambert_W_function
Material fracture which propagates along grain boundaries
brittle second-phase particles at grain boundaries, impurity or atom segregation at grain boundaries, and environmentally-assisted embrittlement. Intergranular
Intergranular_fracture
Protein-coding gene in the species Homo sapiens
of the mitotic spindle assembly complex, which forms a complex with other important proteins. For correct segregation of the cells it is necessary for
BUB3
Protein
"The Lrs4-Csm1 monopolin complex associates with kinetochores during anaphase and is required for accurate chromosome segregation". Cell Cycle. 9 (17): 3611–8
CSM1
Multiprotein and heterotrimeric complex
TRAMP complex (Trf4/Air2/Mtr4p Polyadenylation complex) is a multiprotein, heterotrimeric complex having distributive polyadenylation activity and identifies
TRAMP_complex
Community-government collaboration
into the changes being made. Once communities began to be revitalized, segregation policy followed to determine who was allowed to live where. Housing policy
Community economic development
Community_economic_development
Biological process
chromosomes, catenation of nuclei is aggravated and impedes mitotic segregation. Eukaryotes initiate DNA replication at multiple points in the chromosome
DNA_replication
Healthcare phenomenon
PMID 21551378. Fabio, A (2004-04-01). "Racial segregation and county level intentional injury in Pennsylvania: analysis of hospital discharge data for 1997-1999"
Psychological impact of discrimination on health
Psychological_impact_of_discrimination_on_health
Protein-coding gene in humans
"The Ndc80p complex from Saccharomyces cerevisiae contains conserved centromere components and has a function in chromosome segregation". J Cell Biol
NUF2
Protein-coding gene in humans
T, et al. (2006). "The human Mis12 complex is required for kinetochore assembly and proper chromosome segregation". J. Cell Biol. 173 (1): 9–17. doi:10
NSL1
Locations where civilization emerged
location and a culture from which one of them emerged. A civilization is any complex society characterized by the development of a state, social stratification
Cradle_of_civilization
Protein-coding gene in the species Homo sapiens
complex". J. Biol. Chem. 276 (28): 26666–73. doi:10.1074/jbc.M102493200. PMID 11323433. Chesnokov I, Remus D, Botchan M (2001). "Functional analysis of
ORC6
Type of associative learning process for behavioral modification
satiation; (f) chaining, where a complex behavior is gradually constructed from smaller units. Applied behavior analysis (ABA) is the discipline initiated[vague]
Operant_conditioning
Northern Irish scientist (born 1947)
before the age of sophisticated computer assisted motion analysis—that the brain controls the complex, coordinated movements of the upper limbs by exploiting
J._A._Scott_Kelso
Demolished housing project in St. Louis, US
projects first occupied in 1954 in St. Louis, Missouri, United States. The complex of 33 eleven-story high rises was designed in the modernist architectural
Pruitt–Igoe
Israeli-built barrier in the West Bank
political violence, whereas Palestinians describe it as an element of racial segregation and a representation of Israeli apartheid, often calling it a "wall of
West_Bank_barrier
Species of reptile
Franz; Wikelski, Martin (21 November 2012). "Vegetation dynamics drive segregation by body size in Galapagos tortoises migrating across altitudinal gradients"
Galápagos_tortoise
Conceptual framework
responding to the Supreme Court's decisions that had resulted in the re-segregation of schools. The concept of standpoint theory became particularly relevant
Critical_race_theory
Largest city in Wisconsin, United States
reduce racial tensions and the rate of segregation. With demographic changes in the wake of white flight, segregation in metropolitan Milwaukee is primarily
Milwaukee
Protein complex that regulates the separation of sister chromatids during cell division
manner via the process called loop extrusion. Segregation of chromosomes. Cohesin's activity promotes segregation of chromosomes into chromosomal territories
Cohesin
Chemical process leading to the settling of an insoluble solid from a solution
implantation, and the temperature is high enough that diffusion can lead to segregation into precipitates. Precipitation in solids is routinely used to synthesize
Precipitation_(chemistry)
American human computer and computer programmer (1910–2008)
desegregate the defense industry, and Executive Order 9346 to end racial segregation and discrimination in hiring and promotion among federal agencies and
Dorothy_Vaughan
Seed-bearing part of a flowering plant
chromosomes replicate, recombine and randomly segregate, and then undergo segregation of sister chromatids to produce haploid cells. Union of haploid nuclei
Fruit
Process in mitosis and meiosis
Loss-of-function mutations in these complexes cause abnormal nucleoid morphology and defects in chromosome segregation. Thus, prokaryotes undergo a process
Chromosome_condensation
1974 single by Lynyrd Skynyrd
reference to George Wallace, the governor of Alabama and supporter of racial segregation: In Birmingham, they love the governor (boo boo boo) Now we all did what
Sweet_Home_Alabama
Facility where people are kept as punishment
restraints, nonlethal and lethal weapons, riot-control gear and physical segregation of units and prisoners may all also be present within a prison to monitor
Prison
Protein-coding gene in the species Homo sapiens
a protein with a C2 domain. The protein activates the Beclin1-PI(3)KC3 complex, promoting autophagy and suppressing the proliferation and tumorigenicity
UVRAG
Island jail complex in New York City
of those years, Browder was held in solitary confinement or punitive segregation. He was profiled in The New Yorker in October 2014 for being held for
Rikers_Island
educational segregation as unconstitutional; and the case's influence for the Anderson Bill (1947), which repealed California school segregation. The second
History_of_Mexican_Americans
Political party
Johnson signed the Civil Rights Act of 1964, which outlawed racial segregation. Carmines and Stimson wrote "the Democratic Party appropriated racial
Democratic Party (United States)
Democratic_Party_(United_States)
Government policy allowing certain uses of land in different places
variables associated with higher segregation. With more permissive zoning regulations there are lower levels of segregation; desegregation is higher in places
Zoning
NASA launch facility in Florida
and Artemis programs were carried out from Kennedy Space Center Launch Complex 39 and managed by KSC. Located on the east coast of Florida, KSC is adjacent
Kennedy_Space_Center
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COMPLEX SEGREGATION-ANALYSIS
COMPLEX SEGREGATION-ANALYSIS
COMPLEX SEGREGATION-ANALYSIS
COMPLEX SEGREGATION-ANALYSIS
COMPLEX SEGREGATION-ANALYSIS
COMPLEX SEGREGATION-ANALYSIS
COMPLEX SEGREGATION-ANALYSIS
COMPLEX SEGREGATION-ANALYSIS
COMPLEX SEGREGATION-ANALYSIS
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