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ORC6

  • ORC6
  • Protein-coding gene in the species Homo sapiens

    recognition complex subunit 6 is a protein that in humans is encoded by the ORC6 (ORC6L) gene. The origin recognition complex (ORC) is a highly conserved

    ORC6

    ORC6

    ORC6

  • Origin recognition complex
  • Protein family

    subunits of this complex are encoded by the ORC1, ORC2, ORC3, ORC4, ORC5 and ORC6 genes. ORC is a central component for eukaryotic DNA replication, and remains

    Origin recognition complex

    Origin_recognition_complex

  • Meier-Gorlin syndrome
  • Medical condition

    subunits of Origin Recognition Complex (ORC1, ORC2, ORC3, ORC4, ORC5 and ORC6 genes), CDC6, CDT1, and MCM2-7 (MCM2, MCM3, MCM4, MCM5, MCM6, MCM7). This

    Meier-Gorlin syndrome

    Meier-Gorlin syndrome

    Meier-Gorlin_syndrome

  • DNA replication
  • Biological process

    Pre-replication complex Origin recognition complex ORC1 ORC2 ORC3 ORC4 ORC5 ORC6 Cdc6 Cdt1 Minichromosome maintenance MCM2 MCM3 MCM4 MCM5 MCM6 MCM7 Licensing

    DNA replication

    DNA replication

    DNA_replication

  • Primordial dwarfism
  • Form of dwarfism that results in a smaller body size in all stages of life

    pre-replication complex. Specific genes include origin recognition complex genes ORC1, ORC4 and ORC6, as well as other replication genes CDT1 and CDC6.

    Primordial dwarfism

    Primordial_dwarfism

  • Origin of replication
  • Sequence in a genome

    bind AT-rich DNA, while in metazoan (animal) ORC the TFIIB-like domain of Orc6 is thought to perform a similar function. Metazoan Orc1 proteins also harbor

    Origin of replication

    Origin of replication

    Origin_of_replication

  • Opera Rara
  • London-based opera company and recording label

    (ORC43) Maria de Rudenz (ORC16)* Maria di Rohan (ORC44)* Maria Padilla (ORC6)* Ne m'oubliez pas (ORC4)* Parisina (Donizetti) (ORC40) Pia de' Tolomei (ORC30)*

    Opera Rara

    Opera_Rara

  • POLE2
  • Protein-coding gene in the species Homo sapiens

    Pre-replication complex Origin recognition complex ORC1 ORC2 ORC3 ORC4 ORC5 ORC6 Cdc6 Cdt1 Minichromosome maintenance MCM2 MCM3 MCM4 MCM5 MCM6 MCM7 Licensing

    POLE2

    POLE2

    POLE2

  • Pre-replication complex
  • Protein complex formed during initiation of DNA replication

    sequence TTTTTATG/ATTTA/T. This initiation sequence is recognized by ORC1-5. ORC6 is not known to bind DNA in S. cerevisiae. Initiation sequences in S. pombe

    Pre-replication complex

    Pre-replication complex

    Pre-replication_complex

  • DNA polymerase epsilon
  • Class of enzymes

    Pre-replication complex Origin recognition complex ORC1 ORC2 ORC3 ORC4 ORC5 ORC6 Cdc6 Cdt1 Minichromosome maintenance MCM2 MCM3 MCM4 MCM5 MCM6 MCM7 Licensing

    DNA polymerase epsilon

    DNA_polymerase_epsilon

  • POLE (gene)
  • Protein-coding gene in humans

    Pre-replication complex Origin recognition complex ORC1 ORC2 ORC3 ORC4 ORC5 ORC6 Cdc6 Cdt1 Minichromosome maintenance MCM2 MCM3 MCM4 MCM5 MCM6 MCM7 Licensing

    POLE (gene)

    POLE (gene)

    POLE_(gene)

  • Suman Kumar Dhar
  • Indian biologist (born 1968)

    centered on mammalian DNA replication which assisted him to identify the ORC6 (origin recognition complex subunit six) and its role in viral DNA replication

    Suman Kumar Dhar

    Suman_Kumar_Dhar

  • Eukaryotic DNA replication
  • DNA replication in eukaryotic organisms

    is also bent at the B1 element through interactions with Orc2, Orc5 and Orc6. The bending of origin DNA by ORC appears to be evolutionarily conserved

    Eukaryotic DNA replication

    Eukaryotic DNA replication

    Eukaryotic_DNA_replication

  • Replicon (genetics)
  • DNA region replicating from a single origin

    Pre-replication complex Origin recognition complex ORC1 ORC2 ORC3 ORC4 ORC5 ORC6 Cdc6 Cdt1 Minichromosome maintenance MCM2 MCM3 MCM4 MCM5 MCM6 MCM7 Licensing

    Replicon (genetics)

    Replicon_(genetics)

  • ORC3
  • Protein-coding gene in the species Homo sapiens

    ORC3 has been shown to interact with: MCM4, MCM7, ORC2, ORC4, ORC5, and ORC6. GRCh38: Ensembl release 89: ENSG00000135336 – Ensembl, May 2017 GRCm38:

    ORC3

    ORC3

    ORC3

  • Maria Padilla
  • Opera by Gaetano Donizetti

    Mitchell Choir (recorded June 1980, Henry Wood Hall) CD: Opera Rara Cat: ORC6 1990 Renée Fleming, Stella Zambalis, Hans Gregory Ashbaker, Motti Kaston

    Maria Padilla

    Maria Padilla

    Maria_Padilla

  • ORC4
  • Protein-coding gene in the species Homo sapiens

    shown to interact with: MCM2, MCM3, MCM4, MCM6, ORC1, ORC2, ORC3, ORC5, and ORC6. GRCh38: Ensembl release 89: ENSG00000115947 – Ensembl, May 2017 GRCm38:

    ORC4

    ORC4

    ORC4

  • ORC2
  • Protein-coding gene in the species Homo sapiens

    CDC6, DBF4, MCM10, MCM2 MCM4, MCM5, MCM6, MCM7, ORC1, ORC3, ORC4, ORC5, ORC6, and Replication protein A1. GRCh38: Ensembl release 89: ENSG00000115942

    ORC2

    ORC2

    ORC2

  • List of human protein-coding genes 6
  • HGNC:8489; Q9UBD5 11507 ORC4 HGNC:8490; O43929 11508 ORC5 HGNC:8491; O43913 11509 ORC6 HGNC:17151; Q9Y5N6 11510 ORM1 HGNC:8498; P02763 11511 ORM2 HGNC:8499; P19652

    List of human protein-coding genes 6

    List_of_human_protein-coding_genes_6

  • POLE4
  • Protein-coding gene in the species Homo sapiens

    Pre-replication complex Origin recognition complex ORC1 ORC2 ORC3 ORC4 ORC5 ORC6 Cdc6 Cdt1 Minichromosome maintenance MCM2 MCM3 MCM4 MCM5 MCM6 MCM7 Licensing

    POLE4

    POLE4

    POLE4

  • Anindya Dutta
  • Indian-born American biochemist and cancer researcher

    DNA replication initiation factors and their regulators (Orc3, Orc4, Orc5, Orc6, Cdc6, Cdt1, Cdc45, Mcm10, geminin) and identified how the geminin-Cdt1 balance

    Anindya Dutta

    Anindya_Dutta

  • POLD3
  • Protein-coding gene in the species Homo sapiens

    Pre-replication complex Origin recognition complex ORC1 ORC2 ORC3 ORC4 ORC5 ORC6 Cdc6 Cdt1 Minichromosome maintenance MCM2 MCM3 MCM4 MCM5 MCM6 MCM7 Licensing

    POLD3

    POLD3

    POLD3

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