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Protein-coding gene in the species Homo sapiens
Mitotic checkpoint protein BUB3 is a protein that in humans is encoded by the BUB3 gene. Bub3 is a protein involved with the regulation of the Spindle
BUB3
Protein-coding gene in the species Homo sapiens
BUB3-interacting and GLEBS motif-containing protein ZNF207 is a protein in humans that is encoded by the ZNF207 gene. BUB3, mitotic checkpoint protein
ZNF207
Medical condition
some cells are aneuploid (mosaic). It is caused by mutation BUB1, BUB1B, BUB3, CEP57 or TRIP13. Person with MVA can present with IUGR, microcephaly and
Mosaic variegated aneuploidy syndrome
Mosaic_variegated_aneuploidy_syndrome
Short protein motif that forms a solenoid domain
AHI1, AMBRA1, APAF1, ARPC1A, ARPC1B, ATG16L1, BOP1, BRWD1, BRWD3, BTRC, BUB3, C6orf11, CDC20, CDC40, CDRT1, CHAF1B, CIAO1, CIRH1A, COPA, COPB2, CORO1A
WD40_repeat
Essential spindle checkpoint protein
other spindle checkpoint assembly proteins such as Bub1, BubR1, and Bub3. BubR1 and Bub3 can also form complexes with Cdc20, but it remains to be seen if
Mad2
Protein complex that allows microtubules to attach to chromosomes during cell division
kinetochore, the lower the concentrations of these proteins. At metaphase, CENP-E, Bub3 and Bub1 levels diminish by a factor of about three to four as compared with
Kinetochore
Cell cycle checkpoint
(MCC), which includes SAC proteins, MAD2/MAD3 (mitotic arrest deficient), BUB3 (budding uninhibited by benzimidazole), and CDC20. Other proteins involved
Spindle_checkpoint
Protein-coding gene in the species Homo sapiens
mutations to CRT resistance. BUB1B has been shown to interact with: AP2B1 BRCA2 BUB3 CDC20 MAD2L1 CBP SIRT2 PLK1 PP2A-B56 HDAC1 HDAC2 / HDAC3 SNCG GRCh38: Ensembl
BUB1B
Protein-coding gene in the species Homo sapiens
and signaling. At least thirteen other proteins (Mad1, MAD2, MAD3/BubR1, BUB3, Mps1 etc.) are part of the check point, among which many have been identified
BUB1
Topics referred to by the same term
(yeast) BUB1B, budding uninhibited by benzimidazoles 1 homolog beta (yeast) BUB3, budding uninhibited by benzimidazoles 3 homolog (yeast) Buba, river in Guinea-Bissau
Bub
Mechanism of cell death
is composed of four different proteins known as Mad2, Cdc20, BubR1, and Bub3 in humans. When the mitotic checkpoint complex is formed, it binds to the
Mitotic_catastrophe
Protein-coding gene in humans
consists of several different proteins, including Mad2, Mad3(BubR1), and Bub3. In fact, these three proteins, together with CDC20, likely form the mitotic
CDC20
HGNC:1144; Q9Y297 1728 BUB1 HGNC:1148; O43683 1729 BUB1B HGNC:1149; O60566 1730 BUB3 HGNC:1151; O43684 1731 BUD13 HGNC:28199; Q9BRD0 1732 BUD23 HGNC:16405; O43709
List of human protein-coding genes 1
List_of_human_protein-coding_genes_1
Protein-coding gene in the species Homo sapiens
mammalian active centromeres and interacts with PARP-1, Cenpa, Cenpb and Bub3, but not Cenpc". Human Molecular Genetics. 11 (19): 2319–29. doi:10.1093/hmg/11
PARP2
Chinese-American biologist and oncologist
to epigenetically regulate gene expression, the spindle assembly protein Bub3 to regulate chromosome segregation and mitotic checkpoint in metaphase, and
Zhimin_Lu
American molecular biologist
inhibition of the APC/C in HeLa cells is mediated by a complex of BUBR1, BUB3, CDC20, and MAD2. Journal of cell biology. 2001 Sep 3;154(5):925-36. According
Tim_J._Yen
Protein-coding gene in the species Homo sapiens
Kalitsis P, Choo KH (July 2002). "Centromere proteins Cenpa, Cenpb, and Bub3 interact with poly(ADP-ribose) polymerase-1 protein and are poly(ADP-ribosyl)ated"
CENPA
Protein-coding gene in humans
DYNLT3 is a member of the dynein motor protein family. DYNLT3 binds to BUB3, a spindle checkpoint protein is present on kinetochores at prometaphase
DYNLT3
Protein-coding gene in the species Homo sapiens
mammalian active centromeres and interacts with PARP-1, Cenpa, Cenpb and Bub3, but not Cenpc". Human Molecular Genetics. 11 (19): 2319–2329. doi:10.1093/hmg/11
Centromere_protein_B
Protein-coding gene in the species Homo sapiens
been shown to interact with: Androgen receptor, BCL6, BTG2, BUB1B, BUB1, BUB3, CBFA2T3, CDC20, CDH1, CHD3, CHD4, COUP-TFII, CTBP1, DDX17, DDX5, DNMT3A
HDAC1
Protein-coding gene in the species Homo sapiens
has been shown to interact with: Ataxia telangiectasia and Rad3 related, BUB3, CDC20, CDH1, CHD3, CHD4, DNMT1, EED, EZH2 and FKBP3, GATA4, GTF2I, HDAC10
Histone_deacetylase_2
Protein-coding gene in the species Homo sapiens
inhibition of the APC/C in HeLa cells is mediated by a complex of BUBR1, BUB3, CDC20, and MAD2". J. Cell Biol. 154 (5): 925–36. doi:10.1083/jcb.200102093
MAD2L1
Protein-coding gene in the species Homo sapiens
Wang X, Babu JR, Harden JM, et al. (2001). "The mitotic checkpoint protein hBUB3 and the mRNA export factor hRAE1 interact with GLE2p-binding sequence (GLEBS)-containing
RAE1
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BUB3
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