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Study of RNA transcripts
Transcriptomics technologies are the techniques used to study an organism's transcriptome, the sum of all of its RNA transcripts. The information content
Transcriptomics_technologies
Range of methods designed for assigning cell types
Spatial transcriptomics, or spatially resolved transcriptomics, is a method that captures positional context of transcriptional activity within intact
Spatial_transcriptomics
Analysis technique of genes
Single-cell transcriptomics refers to the quantification and analysis of the transcriptomes of individual cells. Single-cell transcriptomics makes it possible
Single-cell_transcriptomics
in silico computational models such as QSAR and omics such as transcriptomics technologies among other techniques. By using these human-derived biological
New_approach_methodologies
Detection of mRNA molecules
simultaneously, that is, every gene present in a particular cell. Several transcriptomics technologies can be used to generate the necessary data to analyse. DNA microarrays
Gene_expression_profiling
Collection of microscopic DNA spots attached to a solid surface
expression terms Protocol (natural sciences) Biology portal Technology portal Transcriptomics technologies Serial analysis of gene expression RNA-Seq MAGIChip
DNA_microarray
allows transcriptome studies (see also Transcriptomics technologies) based on next-generation sequencing technologies. This technique is largely dependent
List of RNA-Seq bioinformatics tools
List_of_RNA-Seq_bioinformatics_tools
Bioinformatics method
identify significantly enriched or depleted groups of genes. Transcriptomics technologies and proteomics results often identify thousands of genes, which
Gene_set_enrichment_analysis
Set of all RNA molecules in one cell or a population of cells
genome-wide scale in the fields of life sciences and technology. As such, transcriptome and transcriptomics were one of the first words to emerge along with
Transcriptome
Lab technique in cellular biology
Lowe R, Shirley N, Bleackley M, Dolan S, Shafee T (May 2017). "Transcriptomics technologies". PLOS Computational Biology. 13 (5) e1005457. Bibcode:2017PLSCB
RNA-Seq
throughput alignment of shotgun cDNA sequencing reads generated by transcriptomics technologies (e.g. RNA-Seq) using Bowtie first and then mapping to a reference
TopHat_(bioinformatics)
Branch of genomics concerned with the genome of an individual
TIARA (database) – Database of personal genomics information Transcriptomics technologies – Study of RNA transcripts Omics – Suffix in biology Population
Personal_genomics
Chinese genome sequencing company
wide Spatial transcriptomics technology and released the first research findings from a consortium of scientific users of the technology in 2022. In 2022
BGI_Group
Study of genes found in the environment
originally limited to microarray technology, metatranscriptomics studies have made use of transcriptomics technologies to measure whole-genome expression
Metagenomics
Technology for RNA sequencing
tube early in the sequencing library preparation workflow. The transcriptomic technology is compatible with both Illumina and MGI short-read sequencing
BRB-seq
American researcher and immunologist
immune cell function in the tumor microenvironment. Anderson uses transcriptomics technologies and systems biology to understand dysfunctional T-cells.[citation
Ana_Anderson
using transcriptomic data obtained from RNA-Seq and processed using computational phylogenetics. There have been several transcriptomics technologies used
Phylogenetic inference using transcriptomic data
Phylogenetic_inference_using_transcriptomic_data
Laboratory technique of molecular biology
carry out a more detailed estimate for many organisms using transcriptomic technologies. However, research has shown that amplification of the majority
Real-time polymerase chain reaction
Real-time_polymerase_chain_reaction
Suffix in biology
as genomics, proteomics, metabolomics, metagenomics, phenomics and transcriptomics. The related suffix -ome is used to address the objects of study of
Omics
American entrepreneur
Tangram, a deep-learning framework for spatially resolved single-cell transcriptomics. In 2022, Sanger co-founded Anysphere with Michael Truell, Sualeh Asif
Aman_Sanger
applications in transcriptomics and epigenomics. Microarrays was once the mainstay of the transcriptomics the last ten years and array based technology has subsequently
SOLiD_sequencing
Bleackley, Mark; Dolan, Stephen; Shafee, Thomas (2017-05-18). "Transcriptomics technologies". PLOS Computational Biology. 13 (5) e1005457. Bibcode:2017PLSCB
Transcriptome-wide association study
Transcriptome-wide_association_study
her colleagues apply "omic" technologies in their studies including metabolomics, genomics, epigenetics, transcriptomics, proteomics, and whole genome
Qing_Lan
Indian plant biologist (born 1956)
1104/pp.106.091900. PMC 1851844. PMID 17293439. Chloroplast DNA Transcriptomics technologies Serial analysis of gene expression Gene expression Functional
Akhilesh_Kumar_Tyagi
American biotechnology company
epigenetics research. Four months later, 10x Genomics acquired Spatial Transcriptomics, a biotechnology company working in the field of spatial genomics.
10x_Genomics
Precision oncology research company
support personalized cancer treatment. The company integrates genomic, transcriptomic, and proteomic data to improve treatment matching for cancer patients
Astron_(research_center)
South Korean-born American chemist and physicist
A. Goren, N. Hacohen, J. Z. Levin, H. Park, A. Regev, "Single-cell transcriptomics reveals bimodality in expression and splicing in immune cells," Nature
Hongkun_Park
Study of biochemical processes in an individual cell
analysis and subcellular analysis refer to the study of genomics, transcriptomics, proteomics, metabolomics, and cell–cell interactions at the level
Single-cell_analysis
DNA sequencing
rates than previous technologies, which can complicate downstream genome assembly and analysis of the resulting data. These technologies are undergoing active
Third-generation_sequencing
American technology firm
Doyle has led work at Eolas, to create new technologies ranging from Spatial Genomics/Spatial transcriptomics, Code signing, transient-key cryptography
Eolas
Computational and mathematical modeling of complex biological systems
different biological layers, including genomics, transcriptomics, proteomics, and metabolomics. These technologies enable the large-scale measurement of biomolecules
Systems_biology
Computational technique
pseudotemporal ordering is a computational technique used in single-cell transcriptomics to determine the pattern of a dynamic process experienced by cells
Trajectory_inference
research that utilizes a combination of proteomics, genomics, and transcriptomics to aid in the discovery and identification of peptides. Proteogenomics
Proteogenomics
Species of virus
setting. Recombinant or replication-defective AAV has emerged an important technology in the field of gene therapy. This has now led to multiple approved drugs
Adeno-associated_virus
American optogeneticist (born 1971)
in 2026 for his work in optogenetics. He is known for developing the technologies of hydrogel-tissue chemistry (e.g., CLARITY and STARmap) and optogenetics
Karl_Deisseroth
Single cell RNA sequencing method
screening (OPS), which utilizes high-throughput imaging rather than transcriptomics to capture spatial and morphological phenotypes under genetic perturbation
Perturb-seq
Scientific study of chemical processes involving metabolites
sample, such as a single organism. The word was coined in analogy with transcriptomics and proteomics; like the transcriptome and the proteome, the metabolome
Metabolomics
Machine learning framework
stress-strain fields in materials, classifying complex data like spatial transcriptomics, predicting multiphase flow in porous media, and carbon dioxide migration
Neural_operators
Professor in the Department of Genome Sciences at the University of Washington
is known for developing influential open-source software tools for transcriptomics, particularly for RNA-Seq and single-cell RNA-Seq data analysis. His
Cole_Trapnell
Large-scale study of proteins
first dedicated proteomics laboratory in 1995. After genomics and transcriptomics, proteomics is the next step in the study of biological systems. It
Proteomics
Study of cell metabolism in the development of cancer
be applied to oncometabolism, since the changes in cancer's genomic, transcriptomic, and proteomic profiles can result in changes in downstream metabolic
Oncometabolism
Utilizing polymers to examine small biological samples
Edward S. (2021). "Expansion sequencing: Spatially precise in situ transcriptomics in intact biological systems". Science. 371 (6528) eaax2656. doi:10
Expansion_microscopy
Spanish food chemist
neuroprotective capacity of a Dunaliella salina extract - comprehensive transcriptomics and metabolomics study". npj Science of Food. 8 (1). doi:10.1038/s41538-023-00246-7
Alejandro_Cifuentes
RNA sequencing of isolated and/or microdissected cell nuclei
ASD (Autism Spectrum Disorder) patients to identify ASD-associated transcriptomic changes in specific cell types, which is the first cell-type-specific
SnRNA-seq
DNA section marked with start and stop codon of different length
codons. This more general definition can be useful in the context of transcriptomics and metagenomics, where a start or stop codon may not be present in
Open_reading_frame
Database of human proteins
integration of various omics technologies, including antibody-based imaging, mass spectrometry-based proteomics, transcriptomics and systems biology. All
Human_Protein_Atlas
Dense cluser of restriction sites in DNA
cloning technologies, enhancing the accuracy and efficiency of the genetic manipulations. Contemporary MCS designs facilitate such technologies as Gibson
Multiple_cloning_site
Manipulation of an organism's genome
modification and manipulation of an organism's genes using technology. It is a set of technologies used to change the genetic makeup of cells, including the
Genetic_engineering
Laboratory technique
neurological and psychiatric diseases. Comparison of proteomics with transcriptomics has shown that transcriptional data does not necessarily translate
Patch-sequencing
Multidisciplinary research project
the first system for Spatial transcriptomics. Other areas that VEP researchers pioneered include early web technologies, cloud computing, blockchain,
Visible_Embryo_Project
Chemical compound
"Light modulates transcriptomic dynamics upregulating astaxanthin accumulation in Haematococcus: A review". Bioresource Technology. 340 125707. doi:10
Astaxanthin
American neuroscientist (born 1979)
Ho-Jun (2021-01-29). "Expansion sequencing: Spatially precise in situ transcriptomics in intact biological systems". Science. 371 (6528) eaax2656. doi:10
Edward_Boyden
Cellular biology lab technique
of information for the same cell by combining both proteomics and transcriptomics data. For phenotyping, this method has been shown to be as accurate
CITE-Seq
Environmental factor to which a person is exposed
urine, or tissues. Advances in high-throughput -omics technologies such as genomics, transcriptomics, proteomics, and metabolomics, have revolutionized our
Exposome
American genetics researcher
Snyder, Michael (January 2009). "RNA-Seq: a revolutionary tool for transcriptomics". Nature Reviews Genetics. 10 (1): 57–63. doi:10.1038/nrg2484. ISSN 1471-0056
Michael_P._Snyder
Sequencing of all the exons of a genome
Other platforms include Roche 454 sequencer and Life Technologies SOLiD systems, the Life Technologies Ion Torrent and Illumina's Illumina Genome Analyzer
Exome_sequencing
robotics are now being tied closer to cell biology, principally using technologies such as High-content screening. High throughput cell biology dictates
High_throughput_biology
2-color Illumina instruments. Serial analysis of gene expression RNA-Seq Transcriptomics Shiraki, T; Kondo, S; Katayama, S; et al. (2003-12-23). "Cap analysis
Cap analysis of gene expression
Cap_analysis_of_gene_expression
Branch of toxicology and genomics
with genomics or other high-throughput molecular profiling technologies such as transcriptomics, proteomics and metabolomics. Toxicogenomics endeavors to
Toxicogenomics
Emission of light by a living organism
; Bracken-Grissom, Heather D. (1 February 2015). "Phylogenetic and transcriptomic analyses reveal the evolution of bioluminescence and light detection
Bioluminescence
Examines sequence information from individual cells
information from individual cells with optimized next-generation sequencing technologies, providing a higher resolution of cellular differences and a better understanding
Single-cell_sequencing
Order of crustaceans
of Complexity in the Visual Systems of Stomatopods: Insights from Transcriptomics". Integrative and Comparative Biology. 53 (1): 39–49. doi:10.1093/icb/ict060
Mantis_shrimp
Biochemical interaction through which a drug produces its pharmacological effect
needed] Omics based methods use omics technologies, such as chemoproteomics, reverse genetics and genomics, transcriptomics, and proteomics, to identify the
Mechanism_of_action
Species of snake
sexual chromosomes. Using next-generation sequencing and emerging genomic technologies, a de novo high-quality N. naja reference genome was published in 2020
Indian_cobra
American scientist, inventor and entrepreneur (born 1969)
discoveries also formed the basis of the first technologies to automate single-cell genomics and transcriptomics. A central theme of Quake's genomics work
Stephen_Quake
After World War II, research tools and technologies of another level appeared. Thanks to these technologies, it became understandable what really occurs
Timeline_of_aging_research
Sub-discipline of biology
Wang Z., Gerstein M., Snyder M. RNA-Seq: a revolutionary tool for transcriptomics. Nat. Rev. Genet. 10(1):57-63 (2009). Overall C. M., Tam E. M., Kappelhoff
Degradomics
Heuristic for distinct words in a document
Michele; Osella, Matteo (2023). "Emergent statistical laws in single-cell transcriptomic data". Physical Review E. 107 (4) 044403: 2021–06.16.448706. bioRxiv 10
Heaps's_law
Techniques to study geometric data
analysis of geographic data. It may also applied to genomics, as in transcriptomics data, but is primarily for spatial data. Complex issues arise in spatial
Spatial_analysis
American life sciences company
Retrieved 2020-03-12. "New England Biolabs helps Researchers to Tackle Transcriptomics in Bacteria and Blood". The Scientist Magazine. Retrieved 2020-03-25
New_England_Biolabs
Mammals of the order Pholidota
Li, Lin-Miao; et al. (3 September 2020). "Combined proteomics and transcriptomics reveal the genetic basis underlying the differentiation of skin appendages
Pangolin
Biological analysis approach
biology Single-cell multi-omics integration Single-cell transcriptomics Spatial transcriptomics Systems biology Bersanelli, Matteo; Mosca, Ettore; Remondini
Multiomics
Species of spider
has a variety of potential uses, including in fabrics and biomedical technologies, the sequence motifs for genes coding for this silk in the species have
Araneus_ventricosus
Greek-born computational biologist
differences and disease phenotypes, including the first single-cell transcriptomic analysis of Alzheimer's disease (Nature, 2019). Kellis is a member of
Manolis_Kellis
American computational biologist
research that has "pioneered the application of machine learning to transcriptomics and disease research, particularly in maternal and fetal health". "Donna
Donna_Slonim
Medical tubes inserted in the body to extract or administer substances
adapted for endovascular techniques can harvest endothelial cells for transcriptomic analysis. There are also balloon catheters used in angioplasty procedures
Catheter
Methods for diagnosing tuberculosis
Diagnostics). In 2007, a systematic review of NAAT by the NHS Health Technology Assessment Programme concluded that "NAAT test accuracy to be far superior
Diagnosis_of_tuberculosis
Biomedical engineer
eads6847. DeMeo, B. et al. (2025). “Active learning framework leveraging transcriptomics identifies modulators of disease phenotypes.” Science. Liu, N. et al
Alex_K._Shalek
Swiss statistician (born 1983)
inference to infer regulatory relationships from different data modalities (transcriptomic, proteomic, structural, etc.). She is a Full Professor in the Department
Caroline_Uhler
Animals of the phylum Porifera
of ancestrally shared regenerative mechanisms across the Metazoa: A Transcriptomic case study in the Demosponge Halisarca caerulea". Marine Genomics. 37:
Sponge
(2008-01-01). "Linking gene regulation and the exo-metabolome: A comparative transcriptomics approach to identify genes that impact on the production of volatile
Exometabolomics
Type of cell found in pancreatic islets
to study beta-cell function are expanding rapidly with technology. For instance, transcriptomics have allowed researchers to comprehensively analyze gene
Beta_cell
Database of biological information
scientific experiments, published literature, high-throughput experiment technology, and computational analysis.[citation needed] They contain information
Biological_database
(genes) and its interactions with each other and the environment. Transcriptomics, which explores a set of gene and identifies the difference among various
Foodomics
Phylum of microscopic animals
Jørgensen, Aslak; Schiøtt, Morten; et al. (24 July 2019). "Comparative transcriptomics suggest unique molecular adaptations within tardigrade lineages". BMC
Tardigrade
Measurable indicator
markers that might be discovered using genomics, proteomics technologies or imaging technologies. Biomarkers play major roles in medicinal biology. Biomarkers
Biomarker_(medicine)
Sub-field of genomics
tools are used at each step. Operomics aims to integrate genomics, transcriptomics and proteomics to understand the molecular mechanisms that underlie
Oncogenomics
Indian scientist and professor of cancer biology
computational biology, high-throughput data analysis, metabolomics, transcriptomics, regulomics, phenomics, and pharmacogenomics, along with biobanking
Rana_P_Singh
Species of fish native to Southeast Asia
Lin, Yi-Wen; Chen, Chih-Kuan (17 June 2020). "Behavioral and brain- transcriptomic synchronization between the two opponents of a fighting pair of the
Siamese_fighting_fish
Genus of flowering plants
Hill, Theresa A.; Van Deynze, Allen; Bohs, Lynn (2018). "Comparative transcriptomics and genomic patterns of discordance in Capsiceae (Solanaceae)". Molecular
Capsicum
Physiological state of dormant inactivity in order to pass the winter season
PMC 8936132. PMID 35084962. Mugahid, Douaa (27 December 2019). "Proteomic and Transcriptomic Changes in Hibernating Grizzly Bears Reveal Metabolic and Signaling
Hibernation
Species of cricket
physiology, and the use of crickets as sustainable food and feed. Earlier transcriptomic analyses across life stages supported gene discovery and functional
House_cricket
Neuroscientist
Marx, Vivien (January 2021). "Method of the Year: spatially resolved transcriptomics". Nature Methods. 18 (1): 9–14. Bibcode:2021NaMet..18....9M. doi:10
Hongkui_Zeng
Family of birds
and sites in high-elevation hummingbirds revealed by comparative transcriptomics". Genome Biology and Evolution. 11 (6): 1573–1585. doi:10.1093/gbe/evz101
Hummingbird
Gene expression database
"The Bgee suite: integrated curated expression atlas and comparative transcriptomics in animals". Nucleic Acids Research. 49 (D1): D831–D847. doi:10.1093/nar/gkaa793
Bgee
Angiotensin II receptor antagonist
Primary Neurons Negatively Correlates with Aging and Senescence: a Transcriptomic Analysis". Molecular Neurobiology. 57 (3): 1656–1673. doi:10.1007/s12035-019-01800-9
Candesartan
Accumulation of brine in a seafloor depression
denitrification pathways have been identified using a combination of transcriptomics and direct isotope tracking. Other DHABs have been analyzed for anammox
Brine_pool
Canadian researcher and molecular biologist
for mTOR and cancer metabolism. Marignani combines technologies such as single-cell transcriptomics and machine learning to interrogate disease processes
Paola_Marignani
Sub-sequence DNA in genetics
calculated with data in dbEST. Gene expression Complementary DNA (cDNA) Transcriptomics IMAGE cDNA clones Whole genome sequencing (WGS) ESTs Factsheet. National
Expressed_sequence_tag
American-Israeli biomedical scientist
T., Feder, M., Levin, M., Hall, B. K. & Yanai, I. Spatiotemporal transcriptomics reveals the evolutionary history of the endoderm germ layer. Nature
Itai_Yanai
travel, tourism, insurance
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