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Large-scale study of proteins
Proteomics is the large-scale study of proteins. The proteome is the entire set of proteins produced or modified by an organism or system. Proteomics
Proteomics
Shotgun proteomics refers to the use of bottom-up proteomics techniques in identifying proteins in complex mixtures using a combination of high performance
Shotgun_proteomics
Medical diagnostic technique
milestones in advances have been: Single-cell proteomics Techniques of SCOPE-MS and prioritized Single Cell ProtEomics (pSCoPE) allow for deep analysis of individual
Proteomic_profiling
The Australasian Proteomics Society (APS) is a learned society formed in 2004 from the Lorne Proteomics Symposia (LPS) meetings. The APS was expanded to
Australasian Proteomics Society
Australasian_Proteomics_Society
American biotechnology company
000-Sample Proteomics Study". Clinical Lab Products. Retrieved 2025-10-29. Wolski, Chris (2025-06-03). "Proteograph Platform Enables 20,000-Sample Proteomics Study"
Seer,_Inc.
Analytical technique to study proteins
Activity-based proteomics, or activity-based protein profiling (ABPP) is a chemoproteomic strategy that employs modular probes to directly assess the functional
Activity-based_proteomics
Canadian medical researcher
Molecular Oncology and directs the Segal Cancer Proteomics Centre and the Warren Y. Soper Clinical Proteomics Centre at the Lady Davis Institute of the Jewish
Christoph_H._Borchers
International working group
The Proteomics Standards Initiative (PSI) is a working group of the Human Proteome Organization. It aims to define data standards for proteomics to facilitate
Proteomics Standards Initiative
Proteomics_Standards_Initiative
Analytical chemistry technique
Quantitative proteomics is an analytical chemistry technique for determining the amount of various proteins, including cofactors, in a sample. The methods
Quantitative_proteomics
in high-throughput proteomics is called top-down proteomics and does not use proteolytic digestion. Essentially, bottom-up proteomics is a relatively simple
Bottom-up_proteomics
Public database of protein mass spectrometry data in Europe
The PRIDE (PRoteomics IDEntifications database) is a public data repository of mass spectrometry-based proteomics data, and is maintained by the European
Proteomics Identifications Database
Proteomics_Identifications_Database
protein identification using mass spectrometry (MS; Bottom Up proteomics). Top-down proteomics using mass spectrometry interrogates protein structure through
Top-down_proteomics
Academic journal
Molecular & Cellular Proteomics. 8: 1–1. doi:10.1074/mcp.E900001-MCP200. "Mission Statement". Molecular & Cellular Proteomics. Archived from the original
Molecular & Cellular Proteomics
Molecular_&_Cellular_Proteomics
Set of proteins that can be expressed by a genome, cell, tissue, or organism
(December 2007). "Viral proteomics: global evaluation of viruses and their interaction with the host". Expert Review of Proteomics. 4 (6): 815–829. doi:10
Proteome
Academic journal
category "Biochemical Research Methods". Volume 1, Issue 1 of Proteomics. "PROTEOMICS - Editorial Board - Wiley Online Library". onlinelibrary.wiley
Proteomics_(journal)
Swiss biologist (born 1954)
spectrometry and proteomics data, and he is one of the inventors of the Isotope-Coded Affinity Tag (ICAT) technique for quantitative proteomics, a technique
Ruedi_Aebersold
Protein molecule receiving signals for a cell
In biochemistry and pharmacology, receptors are proteins that receive and transduce signals that may be integrated into biological systems. These signals
Receptor_(biochemistry)
Stem cells
Stem cell proteomics is a developing field of omics that analyzes the proteomes of stem cells. The main interest of the application of proteomics on stem
Stem_cell_proteomics
Chemist
in proteomics and the study of Alzheimer's disease, sepsis, and aging. She has developed a novel multiplexing strategy for quantitative proteomics called
Renã_A._S._Robinson
Academic journal
Abstracts Service, and EMBASE. "Clinical Proteomics". BioMed Central. Retrieved 2021-08-05. "Publication: Clinical Proteomics". Ingenta Connect. Archived from
Clinical_Proteomics
Proteomics research center
The Netherlands Proteomics Centre (NPC) is a Dutch research center in the field of proteomics. The research is focused on the proteome, the entire set
Netherlands_Proteomics_Centre
American chemist
the director of proteomics research at the Pacific Northwest National Laboratory (PNNL). Smith is also director of the NIH Proteomics Research Resource
Richard_D._Smith
Academic journal
Journal of Proteomics is a peer-reviewed scientific journal published by Elsevier. It is the official journal of the European Proteomics Association
Journal_of_Proteomics
Molecules which increase enzyme activity
Enzyme activators are molecules that bind to enzymes and increase their activity. They are the opposite of enzyme inhibitors. These molecules are often
Enzyme_activator
Oncologist
Clinical Inviestigation in 2012. Paulovich is an expert in proteomics. Her targeted proteomics method uses multiple reaction monitoring mass spectrometry
Amanda_Paulovich
Study of the structure of every protein in a genome
Medicine portal Hi-C (genomic analysis technique) Genomics Omics Structural proteomics Protein Structure Initiative Chandonia JM, Brenner SE (January 2006).
Structural_genomics
Suffix in biology
emerging field of biological research at the intersection of proteomics and genomics. Proteomics data used for gene annotations. Structural genomics: Study
Omics
Metalloprotease enzyme
ADAMTS13 (a disintegrin and metalloproteinase with a thrombospondin type 1 motif, member 13)—also known as von Willebrand factor-cleaving protease (VWFCP)—is
ADAMTS13
American chemist
mass spectrometry, primarily its application to proteomics. He is known mainly for top-down proteomics and the development of the fragmentation technique
Neil_Kelleher_(scientist)
Russian chemist
growth have supported aspects of the hypothesis. Proteomics and biomarkers — Discovery of proteomic signatures in neurodegenerative diseases such as Alzheimer’s
Roman_Zubarev
Data analysis software for proteomics
The Trans-Proteomic Pipeline (TPP) is an open-source data analysis software for proteomics developed at the Institute for Systems Biology (ISB) by the
Trans-Proteomic_Pipeline
American computer scientist (born 1956)
Oncology Laboratory at USC. He co-founded Applied Proteomics (API) with David Agus to make proteomics-based biomarker discovery practical. Hillis and his
Danny_Hillis
Study of all proteins in an environment
Metaproteomics (also community proteomics, environmental proteomics, or community proteogenomics) is an umbrella term for experimental approaches to study
Metaproteomics
Academic journal
Genomics and Proteomics was an open-access peer-reviewed academic journal that published papers in the fields of human genomics and proteomics, systems biology
Human_Genomics_and_Proteomics
Bioinformatics company
analysis in genomics and proteomics. The company provided a line of products that serve gene expression, sequencing, and proteomics markets. Customers included
Integromics
Italian chemist
(May 2018). "Anton Chekhov and Robert Koch Cheek to Cheek: A Proteomic Study". Proteomics. 18 (9) 1700447. doi:10.1002/pmic.201700447. PMID 29522652. S2CID 3810120
Pier_Giorgio_Righetti
Dutch bioinformatics organization
homepage "Netherlands Bioinformatics for Proteomics Platform". "Proteomics Data Processing Workflow". "Dutch Proteomics Platform". "BTN/GOBLET meeting | GOBLET"
Netherlands Bioinformatics Centre
Netherlands_Bioinformatics_Centre
Tandem mass spectrometry method
Resolution and High Mass Accuracy Quantitative, Targeted Proteomics". Molecular & Cellular Proteomics. 11 (11): 1475–1488. doi:10.1074/mcp.O112.020131. ISSN 1535-9476
Selected_reaction_monitoring
American chemical biologist
Institute in La Jolla, California. Considered a co-inventor of activity-based proteomics and a substantial contributor to research on the endocannabinoid system
Benjamin_Cravatt_III
Containers for scientific data
2012). "File formats commonly used in mass spectrometry proteomics". Molecular & Cellular Proteomics. 11 (12): 1612–21. doi:10.1074/mcp.R112.019695. PMC 3518119
Mass_spectrometry_data_format
Type of mass spectrometry
spectrometer, this is called "bottom-up proteomics". Shotgun proteomics is a variant of bottom up proteomics in which proteins in a mixture are digested
Tandem_mass_spectrometry
Chemical tagging technique used in quantitative proteomics
Isobaric labeling is a mass spectrometry strategy used in quantitative proteomics. Peptides or proteins are labeled with chemical groups that have nominally
Isobaric_labeling
Form of protein microarray
"Dual-color proteomic profiling of complex samples with a microarray of 810 cancer-related antibodies". Molecular & Cellular Proteomics. 9 (6): 1271–80
Antibody_microarray
Canadian cell biologist
Canadian National Proteomics Network Prix D’Excellence Award for Outstanding Contribution and Leadership to the Canadian Proteomics Community (2010).
John_J._M._Bergeron
Iranian-American physician and entrepreneur
and biotechnology executive. His work has focused on nanomedicine and proteomics, including nanoparticle technologies for targeted drug delivery and protein
Omid_Cameron_Farokhzad
Scientific study of life
Photobiology Phycology Phylogenetics Physiology Pomology Primatology Proteomics Protistology Quantum biology Relational biology Reproductive biology Sociobiology
Biology
Medical condition
Hay–Wells syndrome (also known as AEC syndrome; see Etymology) is one of at least 150 known types of ectodermal dysplasia. These disorders affect tissues
Hay–Wells_syndrome
Software for analysis of mass spectrometric data
Skyline is an open source software for targeted proteomics and metabolomics data analysis. It runs on Microsoft Windows and supports the raw data formats
Skyline_(software)
Scientific study of animals
Photobiology Phycology Phylogenetics Physiology Pomology Primatology Proteomics Protistology Quantum biology Relational biology Reproductive biology Sociobiology
Zoology
Laboratory technique for quantitative proteomics
SILAC, as a simple and accurate approach to expression proteomics". Molecular & Cellular Proteomics. 1 (5): 376–386. doi:10.1074/mcp.M200025-MCP200. PMID 12118079
Stable isotope labeling by amino acids in cell culture
Stable_isotope_labeling_by_amino_acids_in_cell_culture
Biochemist
Hunter Chair at the Salk Institute for Biological Studies. She uses proteomics to study transcription elongation and molecular biology to understand
Katherine_Jones_(academic)
Academic journal
an open-access scientific journal covering all areas of genomics and proteomics. The journal was established in 2000 and is published by BioMed Central
BMC_Genomics
Branch of biology that studies cells
Photobiology Phycology Phylogenetics Physiology Pomology Primatology Proteomics Protistology Quantum biology Relational biology Reproductive biology Sociobiology
Cell_biology
Computational biologist
datasets. Key areas include: Proteomics: Developing methods for analyzing mass spectrometry data from shotgun proteomics experiments, including the widely
William_Stafford_Noble
German physicist and biochemist (born 1959)
biochemist. He is doing research in the area of mass spectrometry and proteomics. Born in Thuine, Lower Saxony, he studied mathematics and physics at the
Matthias_Mann
Subfield
proteomics measures the localization and abundance of proteins at the subcellular level across a tissue. Immunohistochemistry-based spatial proteomic
Spatial_biology
Techniques used to study protein–small molecule interactions
Chemoproteomics (also known as chemical proteomics) entails a broad array of techniques used to identify and interrogate protein-small molecule interactions
Chemoproteomics
American proteomicist
Associate Editor of Clinical Proteomics and a member of the Editorial Boards of Molecular and Cellular Proteomics, Proteomics, and the Journal of Clinical
Akhilesh_Pandey
Species of bacterium
Hydrogenobacter thermophilus is an extremely thermophilic, straight rod (bacillus) bacterium. TK-6 is the type strain for this species. It is a Gram negative
Hydrogenobacter_thermophilus
Chinese biotechnology company
that serves the genetic sequencing, genotyping and gene expression, and proteomics markets. Its headquarters are located in Shenzhen, Guangdong, China. In
MGI_(company)
quantitation (iTRAQ) is an isobaric labeling method used in quantitative proteomics by tandem mass spectrometry to determine the amount of proteins from different
Isobaric tag for relative and absolute quantitation
Isobaric_tag_for_relative_and_absolute_quantitation
Italian molecular biologist
Zolla, Lello (2008). "Proteomics applied on plant abiotic stresses: Role of heat shock proteins (HSP)". Journal of Proteomics. 71 (4): 391–411. doi:10
Lello_Zolla
Incredibly small, unique extremophile Archaea species found deep in an acidic mine
Archaeal Richmond Mine acidophilic nanoorganisms (ARMAN) were first discovered in an extremely acidic mine located in northern California (Richmond Mine
Archaeal Richmond Mine acidophilic nanoorganisms
Archaeal_Richmond_Mine_acidophilic_nanoorganisms
Mass spectrometry proteomic analysis software suite
PRM data with various workflows. PEAKS Studio is a proteomics software program for bottom-up proteomics data collected by LC-MS and MS/MS designed for peptide
PEAKS
Branch of proteomics
Phosphoproteomics is a branch of proteomics that identifies, catalogs, and characterizes proteins containing a phosphate group as a posttranslational modification
Phosphoproteomics
Scientific discipline
work to improve proteomics through the development of enrichment strategies, chemical affinity tags, and new probes. Samples for proteomics often contain
Chemical_biology
Medical model that tailors medical practices to the individual patient
including health and disease, so proteomics is helpful in early diagnosis. In the case of respiratory disease, proteomics analyzes several biological samples
Personalized_medicine
Type of sexual assault involving sexual intercourse without consent
10 December 2015. Baarda, Benjamin I.; Sikora, Aleksandra E. (2015). "Proteomics of Neisseria gonorrhoeae: the treasure hunt for countermeasures against
Rape
Academic journal
Molecular Cell Research (accessed 21 April 2011) Elsevier: BBA – Proteins and Proteomics (accessed 21 April 2011) Elsevier: BBA – Reviews on Cancer (accessed 21
Biochimica_et_Biophysica_Acta
Academic journal
Comparative Biochemistry and Physiology Part D: Genomics and Proteomics is a peer-reviewed scientific journal that covers research in biochemistry and
Comparative Biochemistry and Physiology D
Comparative_Biochemistry_and_Physiology_D
Turkic ethnic group
193–230. doi:10.4436/jass.10017. PMID 36576953. Combining genomic and proteomic evidence, researchers revealed that these earliest residents in the Tarim
Uyghurs
Mammalian protein found in humans
C1-inhibitor (C1-inh, C1 esterase inhibitor) is a protease inhibitor belonging to the serpin superfamily. Its main function is the inhibition of the complement
C1-inhibitor
American chemist
Electron-transfer dissociation Proteomics Quantitative proteomics and Isobaric labeling 2018, Discovery in Proteomic Sciences Award from the Human Proteome
Joshua_Coon
Specificity in Data-dependent Quantitative Label-free Shotgun Proteomics". Molecular & Cellular Proteomics. 15 (2): 657–668. doi:10.1074/mcp.M115.055897. PMC 4739679
List of mass spectrometry software
List_of_mass_spectrometry_software
"A Metal-coded Affinity Tag Approach to Quantitative Proteomics". Molecular & Cellular Proteomics. 6 (11): 1907–1916. doi:10.1074/mcp.M700152-MCP200. ISSN 1535-9476
Metal-coded_affinity_tag
Analytical chemistry technique
swiftly. LC–MS is used in proteomics as a method to detect and identify the components of a complex mixture. The bottom-up proteomics LC–MS approach generally
Liquid chromatography–mass spectrometry
Liquid_chromatography–mass_spectrometry
Swiss academic
Appel (born 13 April 1959) is a Swiss bioinformatician, professor of proteomics and bioinformatics at the University of Geneva and executive director
Ron_Appel
measured by mass spectrometry and its analysis constitutes a type of proteomics known as secretomics. The term secretome was coined by Tjalsma and colleagues
Secretome
(ICAT) is an in-vitro isotopic labeling method used for quantitative proteomics by mass spectrometry that uses chemical labeling reagents. These chemical
Isotope-coded_affinity_tag
International consortium
and it promotes the development and awareness of proteomics research, advocates on behalf of proteomics researchers throughout the world, and facilitates
Human_Proteome_Organization
American physician
Applied Proteomics at Cedars-Sinai Medical Center in Los Angeles, he led multidisciplinary research on the development and use of proteomic technologies
David_Agus
Professor of biochemistry
2012-05-02. Retrieved 2022-09-15. "Cambridge Centre for Proteomics". Cambridge Centre for Proteomics, University of Cambridge. 2018-08-06. Retrieved 2022-09-15
Kathryn_S_Lilley
Czechoslovak-born Swiss immunologist (born 1937)
Immunology (SSAI)". SSAI. Retrieved 25 October 2025. "Swiss Proteomics Society". Swiss Proteomics Society. Retrieved 25 October 2025. "Udělené čestné oborové
Ivan_Lefkovits
Computational and mathematical modeling of complex biological systems
Afkhami, Ehsan; Ramoni, Marco F. (2007). "Bayesian methods for proteomics". Proteomics. 7 (16): 2843–2855. doi:10.1002/pmic.200700422. ISSN 1615-9861
Systems_biology
studies that use proteomic information, often derived from mass spectrometry, to improve gene annotations. The utilization of both proteomics and genomics
Proteogenomics
Genome regions affecting protein levels
analyses are only possible because of the growing field of proteomics. Scientists who study proteomics use techniques like mass spectrometry and affinity-based
Protein quantitative trait loci
Protein_quantitative_trait_loci
Dutch chemist
Scientific as the Orbitrap EMR and UHMR. In proteomics, Heck is most renowned for his work on quantitative proteomics, interactomics, and the analysis of post-translational
Albert_J._R._Heck
Indian scientist
Journal of Proteomics and Bioinformatics Reviewer of scientific journals: Annals of Neurology, Journal of Proteome Research, Proteomics, Proteomics: Clinical
R._Sirdeshmukh
Species of virus
Adeno-associated viruses (AAV) are small viruses that infect humans and some other primate species. They belong to the genus Dependoparvovirus, which in
Adeno-associated_virus
Study of microscopic organisms (microbes)
Photobiology Phycology Phylogenetics Physiology Pomology Primatology Proteomics Protistology Quantum biology Relational biology Reproductive biology Sociobiology
Microbiology
Family of protein kinases
In molecular biology, ribosomal s6 kinase (rsk) is a family of protein kinases involved in signal transduction. There are two subfamilies of rsk, p90rsk
Ribosomal_s6_kinase
American biologist (born 1938)
colleagues created the technological foundation for the study of genomics and proteomics by developing five groundbreaking instruments - the protein sequencer
Leroy_Hood
Photobiology Phycology Phylogenetics Physiology Pomology Primatology Proteomics Protistology Quantum biology Relational biology Reproductive biology Sociobiology
Glossary_of_biology
Type of knowledge base
scientific research, with notable applications in fields such as genomics, proteomics, and systems biology. In December 1968, the Human Resources Research Organization
Knowledge_graph
amine isotopic labeling of substrates (TAILS) is a method in quantitative proteomics that identifies the protein content of samples based on N-terminal fragments
Terminal amine isotopic labeling of substrates
Terminal_amine_isotopic_labeling_of_substrates
Non-sperm component of semen
; Yi, Xianhua; MacCoss, Michael J.; Swanson, Willie J. (2008-07-29). "Proteomics Reveals Novel Drosophila Seminal Fluid Proteins Transferred at Mating"
Seminal_fluid_protein
Biotech company
(DNA, RNA, PNA). In 2002, Eurogentec acquired Wita Proteomics, a company specialized in proteomics services, based in Berlin (Germany). A few months later
Eurogentec
Science regarding functions in organisms or living systems
Photobiology Phycology Phylogenetics Physiology Pomology Primatology Proteomics Protistology Quantum biology Relational biology Reproductive biology Sociobiology
Physiology
Scientist studying living organisms
Photobiology Phycology Phylogenetics Physiology Pomology Primatology Proteomics Protistology Quantum biology Relational biology Reproductive biology Sociobiology
Biologist
Scientific methodology
of discovery science is proteomics, a technology-driven and technology limited discovery science. Technologies for proteomic analysis provide information
Discovery_science
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PROTEOMICS
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