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See searches and references containing TISSUE MICROARRAY!TISSUE MICROARRAY
Tissue arrangement technique
Tissue microarrays (also TMAs) consist of paraffin blocks in which up to 1000 separate tissue cores are assembled in array fashion to allow multiplex
Tissue_microarray
Form of protein microarray
detected. Antibody microarrays are often used for detecting protein expression from various biofluids including serum, plasma and cell or tissue lysates. Antibody
Antibody_microarray
Collection of microscopic DNA spots attached to a solid surface
A DNA microarray (also commonly known as a DNA chip or biochip) is a collection of microscopic DNA spots attached to a solid surface. Scientists use DNA
DNA_microarray
Small-scale two-dimensional array of samples on a solid support
interactions Tissue microarrays Cellular microarrays (also called transfection microarrays) Chemical compound microarrays Antibody microarrays Glycan arrays
Microarray
Group of similar cells performing a specific function
Generative tissue – Type of material used in medicine Laser capture microdissection Tissue microarray – Tissue arrangement technique Tissue stress Jones
Tissue_(biology)
Loose connective tissue composed mostly by adipocytes
and has been used extensively in the study of adipose tissue. One such study used microarray analysis in conjunction with Ingenuity IPA software to look
Adipose_tissue
Substrates performing biochemical reactions
Patch Clamp Protein array Sequencing Single nucleotide polymorphism Tissue microarray "High-Level Synthesis of Digital Microfluidic Biochips" (PDF). Duke
Biochip
Cancer originating in connective tissue
O'Connell JX, Gilks CB, Sorensen PH, Linn S, et al. (October 2003). "Tissue microarray validation of Epidermal growth factor receptor and SALL2 in synovial
Sarcoma
Topics referred to by the same term
theory of Forms Thrombotic microangiopathy Tissue microarray, device for analysing many histological tissue samples Transcription mediated amplification
TMA
Tree-based ensemble machine learning methods
Belldegrun AS, Palotie A, Horvath S (April 2005). "Tumor classification by tissue microarray profiling: random forest clustering applied to renal cell carcinoma"
Random_forest
Schoenberg Fejzo M, Slamon DJ. Tissue microarrays from frozen tissues-OCT technique. Methods Mol Biol. 2010, 664:73-80. "Frozen Tissue Array". BioChain Institute
Frozen_tissue_array
Common application of immunostaining
and tissues. The combination of immunohistochemistry and tissue microarrays provides protein expression patterns in a large number of different tissue types
Immunohistochemistry
Device for tracking proteins
A protein microarray (or protein chip) is a high-throughput method used to track the interactions and activities of proteins, and to determine their function
Protein_microarray
Study of RNA transcripts
biological sciences. There are two key contemporary techniques in the field: microarrays, which quantify a set of predetermined sequences, and RNA-Seq, which
Transcriptomics_technologies
Imaging system
of N-glycans in formalin-fixed paraffin embedded clinical tissue blocks and tissue microarrays". PLOS ONE. 9 (9) e106255. Bibcode:2014PLoSO...9j6255P. doi:10
MALDI_imaging
This microarray format is very similar to DNA microarray, protein microarray and antibody microarray. In chemical genetics research, they are routinely
Chemical_compound_microarray
Foran, D. J. (2006). "Analytica Chimica Acta - Advances in cancer tissue microarray technology: Towards improved understanding and diagnostics". Analytica
Automated tissue image analysis
Automated_tissue_image_analysis
Tissue inhibitors of metalloproteinases (TIMPs) are specific endogenous protease inhibitors to the matrix metalloproteinases. There are four TIMPs; TIMP1
Tissue inhibitor of metalloproteinase
Tissue_inhibitor_of_metalloproteinase
Type of spinal cancer
were phosphorylated in 92%, 96% and 98% of cases, respectively. In a tissue microarray containing 21 chordomas Platelet-derived growth factor receptor-beta
Chordoma
Genetic testing technique
gastric mucosa-associated lymphoid tissue lymphomas: a fluorescent in situ hybridization study using a tissue microarray approach". Human Pathology. 39 (4):
Fluorescence in situ hybridization
Fluorescence_in_situ_hybridization
Microscopic interpretation of cells to detect cancer and other abnormalities
assurance. For example, when a cytotechnologist is working to construct a tissue microarray (TMA), they must check in with the supervising pathologist at multiple
Cytotechnology
Computational analysis of large, complex sets of biological data
in a tissue context can be achieved through affinity proteomics displayed as spatial data based on immunohistochemistry and tissue microarrays. Gene
Bioinformatics
A reverse phase protein lysate microarray (RPMA) is a protein microarray designed as a dot-blot platform that allows measurement of protein expression
Reverse phase protein lysate microarray
Reverse_phase_protein_lysate_microarray
World Community Grid volunteer computing subproject
by identifying visual patterns in large numbers of tissue microarrays taken from archived tissue samples. By correlating the pattern data with information
Help_Defeat_Cancer
Hybridization Analysis of Formalin Fixed Paraffin Embedded Tissues, Including Tissue Microarrays". Fluorescence in situ Hybridization (FISH). Methods in
Chromogenic in situ hybridization
Chromogenic_in_situ_hybridization
Set of all RNA molecules in one cell or a population of cells
The first transcriptome studies were based on microarray techniques (also known as DNA chips). Microarrays consist of thin glass layers with spots on which
Transcriptome
Pharmaceutical compound
brain cortex tetrapeptide Cortagen on gene expression in mouse heart by microarray". Neuro Endocrinology Letters. 25 (1–2): 87–93. PMID 15159690. Zarubina
Cortagen
Method to evaluate biological samples
the human genome, with these fragments being used as probes on the DNA microarray. Now probes of various origins such as cDNA, genomic PCR products and
Comparative genomic hybridization
Comparative_genomic_hybridization
Laboratory technique to localize nucleic acids
Huntsman, David (2007-05-01). "Fluorescent in situ hybridization on tissue microarrays: challenges and solutions". Journal of Molecular Histology. 38 (2):
In_situ_hybridization
Fragment of RNA or DNA able to be chemically labeled
methods, and in other gene technologies, such as nucleic acid and tissue microarrays. Scorpion® probes Molecular Beacon probes TaqMan® probes LNA® (Locked
Hybridization_probe
Throughput Quantification of Protein Expression of Cancer Antigens in Tissue Microarray Using Quantum Dot Nanocrystals". Nano Letters. 6 (12). American Chemical
Warren_Chan
biomarkers includes: 2D-PAGE LC-MS SELDI-TOF (or MALDI-TOF) Antibody array Tissue microarray The term metabolomic has been recently introduced to address the global
Biomarker_discovery
Use of living systems and organisms to develop or make useful products
techniques used in biotechnology include tissue culture, which allows researchers to grow cells and tissues in the lab for research and medical purposes
Biotechnology
Protein-coding gene in the species Homo sapiens
"Insulin-like growth factor-binding protein-3 in breast cancer: analysis with tissue microarray". Anticancer Research. 29 (4): 1131–1135. PMID 19414355. Xue A, Scarlett
IGFBP3
Enzyme
neoplastic tissues and its sensitivity and specificity in prostate adenocarcinoma: an immunohistochemical study using multiple tumour tissue microarray technique"
Glutamate_carboxypeptidase_II
Group of anti-nuclear antibodies
simultaneously. If anti-dsDNA antibodies are present, incubation of serum and the microarray allow for binding and the dots can then be visualised using a fluorescent
Anti-dsDNA_antibodies
Class of short biopolymers
DNA microarrays are a useful analytical application of oligonucleotides. Compared to standard cDNA microarrays, oligonucleotide based microarrays have
Oligonucleotide
Hematologic cancer that affects lymphocytes
part of the broader group of tumors of the hematopoietic and lymphoid tissues. Risk factors for Hodgkin lymphoma include infection with Epstein–Barr
Lymphoma
Mass spectrometry technique that can visualize the spatial distribution of molecules
of N-Glycans in Formalin-Fixed Paraffin Embedded Clinical Tissue Blocks and Tissue Microarrays". PLOS ONE. 9 (9) e106255. Bibcode:2014PLoSO...9j6255P. doi:10
Mass_spectrometry_imaging
DNA reverse transcribed from RNA
analyze transcriptomic profiles in bulk tissue, single cells, or single nuclei in assays such as microarrays, qPCR, and RNA-seq. In natural forms, cDNA
Complementary_DNA
raised in 2010 by Vulto and Joore, who envisioned creating the tissue equivalent of a microarray for massive parallel testing of therapeutic compounds. The
MIMETAS
Branch of biology that studies biological systems at the molecular level
membrane are probed for modifications using specific substrates. A DNA microarray is a collection of spots attached to a solid support such as a microscope
Molecular_biology
Inflamed tendon in a horse
involved in tissue repair, as evidenced by gene microarray analysis and lead to a fetal like or regenerative tissue response. Depending on the tissue type,
Bowed_tendon
Protein-coding gene in humans
metalloproteinase-11, tissue inhibitor of metalloproteinase-1, and fibronectin are up-regulated in papillary thyroid carcinoma: a cDNA and tissue microarray study".
MMP11
Medical condition
of diffuse large B-cell lymphoma by immunohistochemistry using a tissue microarray". Blood. 103 (1): 275–82. doi:10.1182/blood-2003-05-1545. PMID 14504078
Intravascular_lymphomas
Protein-coding gene in humans
expression in transitional cell carcinoma of the urinary bladder: a tissue microarray study". International Journal of Cancer. 100 (6): 702–5. doi:10.1002/ijc
MAGEA4
Protein-coding gene in the species Homo sapiens
RB, Liu CL, Botstein D, Brown PO, van de Rijn M (October 2003). "Tissue microarray validation of epidermal growth factor receptor and SALL2 in synovial
SALL2
Medical condition
follicular helper T cell markers in nodal peripheral T cell lymphomas: a tissue microarray analysis of 162 cases". Journal of Clinical Pathology. 64 (4): 319–24
Lennert_lymphoma
Large-scale study of proteins
micro array technology, to produce reverse-phase protein microarrays. In this type of microarrays, the whole collection of protein themselves are immobilized
Proteomics
Protein-coding gene in the species Homo sapiens
protein-protein interactions. SH3D21 is expressed in low levels in most tissue. Microarray analysis has shown SH3D21 expression to be decreased in TP63 knockout
SH3D21
Test for early stage breast cancer
signature and uses formalin-fixed-paraffin-embedded (FFPE) or fresh tissue for microarray analysis. It is a laboratory developed test (LDT) which falls into
MammaPrint
Physiologist
proliferation. In: Mechanosensitive Ion Channels (2008) Applications of tissue microarrays in renal physiology and pathology. In: Renal and Urinary Proteomics:
Ali_Mobasheri
Enzyme
Dolled-Filhart M, Camp RL, Kowalski DP, Smith BL, Rimm DL (Feb 2003). "Tissue microarray analysis of signal transducers and activators of transcription 3 (Stat3)
RPS6KA5
Protein-coding gene in the species Homo sapiens
and testicular tissues corroborate this trend. Microarray data posits the expression of LOC105377021 in certain breast cancer tissues, including metastases
LOC105377021
Enzyme found in humans
cyclin D1, D3, E, and p27 in human renal cell carcinoma analysed by tissue microarray". British Journal of Cancer. 88 (9): 1417–23. doi:10.1038/sj.bjc.6600922
PSMD9
Protein found in humans
terms of gene expression, ZNF226 is generally expressed in most tissues. Microarray data illustrates higher expression of ZNF226 within the ovaries.
Zinc_finger_protein_226
Response of fish to environmental hypoxia
common carp suggesting increased oxygen transport throughout fish tissues. Microarray studies done on fish species exposed to hypoxia typically show a
Hypoxia_in_fish
Gene expression database
that provides information on gene expression patterns from RNA-Seq and Microarray studies, and protein expression from Proteomics studies. The Expression
Expression_Atlas
BOINC based volunteer computing project to aid scientific research
by identifying visual patterns in large numbers of tissue microarrays taken from archived tissue samples. By correlating the pattern data with information
World_Community_Grid
American cancer researcher and orthopaedic surgeon
2011). "Evaluation of eIF4E expression in an osteosarcoma-specific tissue microarray". J. Pediatr. Hematol. Oncol. 33 (7): 524–8. doi:10.1097/MPH.0b013e318223d0c1
John_H._Healey
Protein-coding gene in the species Homo sapiens
observed to affect inflammatory responses in bronchial airway tissue on a genetic level. Microarray analysis was used to determine levels of expression in human
C16orf71
Genomic study of immune system regulation and pathogen response
benefit from cDNA microarray analysis of gene expression,” and, thus, heralded the rise of immunomics. Limited by available microarrays and a non-complete
Immunomics
Sub-sequence DNA in genetics
contain enough information to permit the design of precise probes for DNA microarrays that then can be used to determine gene expression profiles. Some authors
Expressed_sequence_tag
Biomedical scientist
cancer, Yang characterizes the molecular signature of tumors using tissue microarray and integrated tumor profiling analyses to identify risk factors for
Xiaohong_Rose_Yang
American scientist and businessman
others. Microarray technologies are widely used for comparing gene expression patterns and other genome features among individuals and their tissues and cells
Patrick_O._Brown
Range of methods designed for assigning cell types
transcript abundance. Frozen tissue samples are cut using cryotome, then fixed, stained, and carefully laid flat onto the microarray. Next, enzymatic permeabilization
Spatial_transcriptomics
Molecular biology technique
fragments, and the probe is RNA extracted from a tissue and radioactively labelled. The use of DNA microarrays that have come into widespread use in the late
Northern_blot
Software project for the analysis of genomic data
that are mainly, but not solely, oriented towards different types of microarrays. The project was started in the Fall of 2001 and is overseen by the Bioconductor
Bioconductor
Protein found in humans
of gene expression, ZNF684 has ubiquitous expression in all human tissues. Microarray data illustrates higher expression of ZNF684 within the liver. This
Zinc_finger_protein_684
Microtechnology
as proteins, cells and tissues have been used in the development of cell-based arrays, microarrays, microfabrication based tissue engineering, and artificial
Bio-MEMS
Lining of the mammalian uterus
L-arginine and sildenafil citrate. Gene expression profiling using cDNA microarray can be used for the diagnosis of endometrial disorders. The European Menopause
Endometrium
Molecular biology technique
of organisms. The general goal of the technique is similar to the DNA microarray. However, SAGE sampling is based on sequencing mRNA output, not on hybridization
Serial analysis of gene expression
Serial_analysis_of_gene_expression
Tumor originating in adipose (fat) tissue
the most common subtype of soft tissue sarcomas, accounting for at least 20% of all sarcomas in adults. Soft tissue sarcomas are rare neoplasms with
Liposarcoma
multiplex PCR, DNA microarray, in situ hybridization, in situ RNA sequencing, DNA sequencing, antibody based immunofluorescence tissue assays, molecular
Molecular_pathology
Field of molecular biology
prior knowledge of what transcripts to study (as microarrays do). RNA sequencing has taken over microarray and SAGE technology in recent years, as noted
Functional_genomics
Protein-coding gene in the species Homo sapiens
testicular cancer evaluated by in situ protein expression analyses on tissue microarrays". Neoplasia. 5 (5): 397–404. doi:10.1016/s1476-5586(03)80042-8. PMC 1502610
GRB7
Protein-coding gene in the species Homo sapiens
According to microarray-assessed tissue expression analysis by NCBI GEO, the gene CXorf64 has average expression levels in most tissues save for, prostate
PRR32
Detection of mRNA molecules
technologies can be used to generate the necessary data to analyse. DNA microarrays measure the relative activity of previously identified target genes.
Gene_expression_profiling
Protein-coding gene in the species Homo sapiens
zinc-fingers and homeoboxes 2 in hepatocellular carcinogenesis: a tissue microarray and clinicopathological analysis". Neoplasma. 54 (3): 207–11. PMID 17447851
ZHX2
Infection of the brain caused by the Japanese encephalitis virus
reported in Culex bitaeniorhynchus in South Korea. Recently, whole genome microarray research of neurons infected with the Japanese encephalitis virus has
Japanese_encephalitis
Application of engineering principles and design concepts to medicine and biology
micro-implants, imaging technologies such as MRI and EKG/ECG, regenerative tissue growth, and the development of pharmaceutical drugs including biopharmaceuticals
Biomedical_engineering
Protein-coding gene in the species Homo sapiens
protein and its decreased expression on nasopharyngeal carcinoma tissue microarray". Protein Expression and Purification. 47 (1): 60–7. doi:10.1016/j
UBAP1
extensive clinical database (LECTOR), huge collections of sarcoma tissue microarrays and longitudinal blood samples from sarcoma patients. EORTC Search
Patrick_Schöffski
Species of fungus
et al. (March 2010). "Serological profiling of a Candida albicans protein microarray reveals permanent host-pathogen interplay and stage-specific responses
Candida_albicans
Protein-coding gene in humans
cables protein expression in human non-small cell lung cancer: a tissue microarray study". Hum. Pathol. 34 (2): 143–9. doi:10.1053/hupa.2003.26. PMID 12612882
CABLES1
Mammalian protein found in Homo sapiens
normal prostate tissue, and immunostaining of prostate tissue microarrays showed not only decreasing ARSB staining in prostate cancer tissue of a higher Gleason
Arylsulfatase_B
Order of amphibians
Susan V.; Gardiner, David M.; Harkins, Tim T.; Voss, S. Randal (2009). "Microarray and cDNA sequence analysis of transcription during nerve-dependent limb
Salamander
Study of disease
reaction (qPCR), multiplex PCR, DNA microarray, in situ hybridization, DNA sequencing, antibody-based immunofluorescence tissue assays, molecular profiling of
Pathology
Chris Ding and Hanchuan Peng, "Minimum Redundancy Feature Selection from Microarray Gene Expression Data". 2nd IEEE Computer Society Bioinformatics Conference
Minimum redundancy feature selection
Minimum_redundancy_feature_selection
Collection of techniques used to analyze biological markers in the genome and proteome
were basically validated on genomic DNA extracted from FFPE tissue. There are also microarrays that utilize hybridization mechanism to diagnose cancer. More
Molecular_diagnostics
Protein-coding gene in the species Homo sapiens
alveolar soft part sarcoma: an immunohistochemical study utilizing tissue microarray". Histopathology. 55 (6): 750–755. doi:10.1111/j.1365-2559.2009.03436
ASPSCR1
Genetic disorder
calcium level homeostasis. No molecular cause was found, but an expanded microarray analysis of the patient found a 225.5 kb deletion on chromosome 11p between
Primrose_syndrome
results. Microarrays of cell analytes, arrays of cell lysate, antibody microarrays, tissue printing, immunoarrays, etc. are also possible with the slide. Due
Nitrocellulose_slide
Protein-coding gene in the species Homo sapiens
Tissue inhibitor of metalloproteinases 2 (TIMP2) is a gene and a corresponding protein. The gene is a member of the TIMP gene family. The protein is thought
TIMP2
Kapur, V. (2004). "Suppression subtractive hybridization coupled with microarray analysis to examine differential expression of genes in virus infected
Suppression subtractive hybridization
Suppression_subtractive_hybridization
Medical specialty
polymerase chain reaction, and nucleic acid microarrays for specialized studies of disease in tissues and cells. Molecular pathology shares some aspects
Anatomical_pathology
Sub-discipline of biology
diseased samples and tissues. Unfortunately, as transcript levels often fail to reflect protein expression levels, gene microarrays are limited in representing
Degradomics
Quiescent stage of the cell cycle in which the cell does not divide
techniques, such as microarray and RNA sequencing. Although variations exist in their individual transcriptomes, most quiescent tissue stem cells share a
G0_phase
American bioinformatician
focus began to shift to post-genomic applications, with an emphasis on microarray analysis. Using a combination of laboratory and computational approaches
John_Quackenbush
Species of Gram-positive bacterium
Although this is a common method, a limitation is the maintenance of the microarray, which detects new allelic profiles, making it a costly and time-consuming
Staphylococcus_aureus
TISSUE MICROARRAY
TISSUE MICROARRAY
Boy/Male
Hindu, Indian, Traditional
Issue
Girl/Female
German, Swedish
Noble; Nobility; God's Promise; God is My Oath; Form of Alice
Girl/Female
English
Diminutive of any name begining with Christ-, for example Christahel, Christian, or Christopher.....
Boy/Male
English
Diminutives of any masculine or feminine name begining with Christ-, for example Christahel,...
Girl/Female
English American Greek
Abbreviation of Teresa, meaning harvester.
Female
English
English pet form of Spanish Teresa, TESSIE means "harvester."Â
Boy/Male
Hindu
Issue
Female
Yiddish
(זִיסֶע) Yiddish name ZISSE means "sweet."
Boy/Male
English
Diminutives of any masculine or feminine name begining with Christ-, for example Christahel,...
Female
English
Variant spelling of English Sissy, SISSIE means "blind."
Girl/Female
Latin
F: Ameaning bringer of joy. In the Divine Comedy, Beatrice was Dante's guide through Paradise,...
Male
Yiddish
Yiddish form of Hebrew Yisrael, ISSUR means "God prevails" or "contender; soldier of God."
Female
English
Variant spelling of English Missy, MISSIE means "honey-sap."
Girl/Female
English
Diminutive of any name begining with Christ-, for example Christahel, Christian, or Christopher.....
Boy/Male
Tamil
Issue
Girl/Female
Arabic
Brocade; Gold Tissue
Girl/Female
Arabic
Brocade; Gold Tissue
Male
Swedish
Pet form of Swedish Nils, NISSE means "victor of the people."
Girl/Female
Russian
Abbreviation of Natasha - the Russian form of the English Natalie 'Born at Christmas.
Biblical
fissure
TISSUE MICROARRAY
TISSUE MICROARRAY
Boy/Male
Tamil
Ilamurugu | இலாமà¯à®°à¯à®•à¯
Young Lord Murugan
Boy/Male
Indian, Sanskrit
Abode of Light
Boy/Male
Hindu, Indian, Kannada, Marathi, Tamil
Happy Boy; One who Brings Happiness
Boy/Male
Hebrew
Song.
Girl/Female
Tamil
Tanugna | தநà¯à®‚கà¯à®¨à®¾
Boy/Male
Arabic, Muslim
Won; Success
Boy/Male
Hindu, Indian, Marathi
Best Among the Virtuous
Surname or Lastname
English
English : variant of Dyke.
Girl/Female
Tamil
Produced from petals
Boy/Male
Gujarati, Hindu, Indian, Kannada, Malayalam, Marathi, Mythological, Sanskrit, Sindhi, Telugu
Lord Shiva
TISSUE MICROARRAY
TISSUE MICROARRAY
TISSUE MICROARRAY
TISSUE MICROARRAY
TISSUE MICROARRAY
a.
Clothed in, or adorned with, tissue; also, variegated; as, tissued flowers.
imp. & p. p.
of Tissue
v. i.
To extend; to pass or open; as, the path issues into the highway.
n.
One who issues, emits, or publishes.
v. t.
To send out; to put into circulation; as, to issue notes from a bank.
v. t.
To deliver for use; as, to issue provisions.
n.
The act of sending out, or causing to go forth; delivery; issuance; as, the issue of an order from a commanding officer; the issue of money from a treasury.
n.
Fig.: Web; texture; complicated fabrication; connected series; as, a tissue of forgeries, or of falsehood.
v. t.
To form tissue of; to interweave.
v. i.
To close; to end; to terminate; to turn out; as, we know not how the cause will issue.
v. i.
To proceed, as from a source; as, water issues from springs; light issues from the sun.
n.
A second or repeated issue.
n.
In pleading, a single material point of law or fact depending in the suit, which, being affirmed on the one side and denied on the other, is presented for determination. See General issue, under General, and Feigned issue, under Feigned.
n.
That which passes, flows, or is sent out; the whole quantity sent forth or emitted at one time; as, an issue of bank notes; the daily issue of a newspaper.
v. t. & i.
To issue a second time.
a.
Tissue-producing; connected with the formation and development of the organic tissues.
n.
One of the elementary materials or fibres, having a uniform structure and a specialized function, of which ordinary animals and plants are composed; a texture; as, epithelial tissue; connective tissue.
v. i.
In pleading, to come to a point in fact or law, on which the parties join issue.
v. t.
To send out officially; to deliver by authority; as, to issue an order; to issue a writ.
imp. & p. p.
of Issue