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Protein metabolic pathway
The Purine Nucleotide Cycle is a metabolic pathway in protein metabolism requiring the amino acids aspartate and glutamate. The cycle is used to regulate
Purine_nucleotide_cycle
Chemical reactions and pathways involving lysis of purine nucleotides
Purine metabolism refers to the metabolic pathways to synthesize and break down purines that are present in many organisms. Purines are biologically synthesized
Purine_metabolism
Sudden fatigue during endurance sports
reaction and purine nucleotide cycle. Amino acids are vital to the purine nucleotide cycle as they are precursors for purines, nucleotides, and nucleosides;
Hitting_the_wall
Metabolic processes for energy production
adenylate kinase (myokinase) reaction is primarily regulated by the purine nucleotide cycle. This system is known as anaerobic glycolysis. "Glycolysis" refers
Bioenergetic_systems
Chemical compound
ribonucleotide of hypoxanthine and the first nucleotide formed during the synthesis of purine nucleotides. It can also be formed by the deamination of
Inosinic_acid
Process
AMP). Carbohydrate metabolism DNA Nucleic acid Protein metabolism Purine nucleotide cycle RNA Voet, Donald; Voet, Judith; Pratt, Charlotte (2008). Fundamentals
Nucleic_acid_metabolism
Exercise phenomenon
reaction and purine nucleotide cycle. Amino acids are vital to the purine nucleotide cycle as they are precursors for purines, nucleotides, and nucleosides;
Second_wind
Excess uric acid in the blood
acid due to increased turnover of adenosine nucleotides by the myokinase reaction and purine nucleotide cycle. High intake of alcohol (ethanol), a significant
Hyperuricemia
Biological molecules constituting nucleic acids
phosphates make up the phosphate group. In nucleic acids, nucleotides contain either a purine or a pyrimidine base—i.e., the nucleobase molecule, also
Nucleotide
Human disease caused by deficiency of a muscle enzyme
cells is low, and is a part of protein metabolism. In the purine nucleotide cycle, three nucleotides: AMP (adenosine monophosphate), IMP (inosine monophosphate)
Glycogen storage disease type V
Glycogen_storage_disease_type_V
Metabolic enzyme
reaction and the purine nucleotide cycle. The myokinase reaction produces AMP (2 ADP → ATP + AMP), and then the purine nucleotide cycle both uses AMP and
Phosphoglucomutase
Organic compound
acid urate. Uric acid is a product of the metabolic breakdown of purine nucleotides, and it is a normal component of urine. High blood concentrations
Uric_acid
Muscular diseases caused by defects in metabolic processes
muscle cell. Nucleotide metabolism disorder—defect in purine nucleotide cycle enzyme (such as AMP deaminase deficiency). Purine nucleotide metabolism is
Metabolic_myopathy
Increased blood pH
increased ADP and AMP, increased rise in venous ammonia (from the purine nucleotide cycle), increased epinephrine (adrenaline), increased plasma free fatty
Alkalosis
Chemical reaction
pathway. Examples of such are found in the citric acid cycle (TCA cycle). In normal function of this cycle for respiration, concentrations of TCA intermediates
Anaplerotic_reactions
Disease resulting from a lack of vitamin C
muscle contraction. (For low ATP within the muscle cell, see also Purine nucleotide cycle.) In the synthesis of collagen, ascorbic acid is required as a
Scurvy
Biological process
similar substance. The term often refers to nucleotide salvage in particular, in which nucleotides (purine and pyrimidine) are synthesized from intermediates
Nucleotide_salvage
Chemical compound
deaminase, freeing an ammonia group. In a catabolic pathway, the purine nucleotide cycle, adenosine monophosphate can be converted to uric acid, which is
Adenosine_monophosphate
Metabolic disorder leading to muscle dysfunction
reduces energy that would be available to the cell through the purine nucleotide cycle. Instead of being converted to IMP, the AMP builds up in the cells
Adenosine monophosphate deaminase deficiency type 1
Adenosine_monophosphate_deaminase_deficiency_type_1
Enzyme
adenylosuccinate to AMP and fumarate as part of the purine nucleotide cycle. ASL catalyzes two reactions in the purine biosynthetic pathway that makes AMP; ASL cleaves
Adenylosuccinate_lyase
Biochemical process involving the production of fats
flux through not only the fat synthesis pathway but also the citric acid cycle. Insulin affects ACC in a similar way to PDH. It leads to its dephosphorylation
Lipogenesis
High energy storage compounds
adenylate kinase (myokinase) reaction is primarily regulated by the Purine Nucleotide Cycle. Selected Topics in the History of Biochemistry, G Semenza Wallimann
Phosphagen
leads to increased turnover of adenosine nucleotides by the myokinase reaction and purine nucleotide cycle. Research has shown that declining levels
Pseudohypoxia
Any of several glycosylamines comprising a nucleobase and a sugar molecule
is linked through a glycosidic bond to the N9 of a purine or the N1 of a pyrimidine. Nucleotides are the molecular building blocks of DNA and RNA. This
Nucleoside
Interconnected biochemical reactions releasing energy
The citric acid cycle—also known as the Krebs cycle, Szent–Györgyi–Krebs cycle, or TCA cycle (tricarboxylic acid cycle)—is a series of biochemical reactions
Citric_acid_cycle
Set of biological pathways
by physico-chemical processes. RNA is composed of pyrimidine and purine nucleotides, both of which are necessary for reliable information transfer, and
Pyrimidine_metabolism
Chemical compound
Guanosine-5'-triphosphate (GTP) is a purine nucleoside triphosphate. It is one of the building blocks needed for the synthesis of RNA during the transcription
Guanosine_triphosphate
Enzyme
supply of intermediates in a metabolic pathway) for the tricarboxylic acid cycle (essential to provide oxaloacetate), when intermediates are removed for
Pyruvate_carboxylase
Enzyme
two isozymes are present: one involved in purine biosynthesis and the other in the purine nucleotide cycle. The crystal structure of adenylosuccinate
Adenylosuccinate_synthase
Energy-carrying molecule in living cells
aa-AMP + tRNA ⟶ aa-tRNA + AMP The amino acid is coupled to the penultimate nucleotide at the 3′-end of the tRNA (the A in the sequence CCA) via an ester bond
Adenosine_triphosphate
Set of chemical reactions in organisms
first pathways of enzyme-based metabolism may have been parts of purine nucleotide metabolism, while previous metabolic pathways were a part of the ancient
Metabolism
Chemical compound
monophosphate (S-AMP), is an intermediate in the interconversion of purine nucleotides inosine monophosphate (IMP) and adenosine monophosphate (AMP). The
Adenylosuccinate
Chemical compound
5'-Guanylyl imidodiphosphate (GDPNP) is a purine nucleotide. It is an analog of guanosine triphosphate in which one of the oxygen atoms is replaced with
5'-Guanylyl_imidodiphosphate
Biopolymer molecule composed of nucleotide monomers
governed by physico-chemical processes. RNA is composed of purine and pyrimidine nucleotides, both of which are necessary for reliable information transfer
Polynucleotide
Chemical compound
platelet activation via adenosine receptors.[citation needed] Nucleoside Nucleotide DNA RNA Oligonucleotide Apyrase Phosphate Adenosine diphosphate ribose
Adenosine_diphosphate
Class of enzymes
(MADD) Glycogenolysis McArdle disease (GSD-V) Metabolic myopathies Purine nucleotide cycle § Pathology PDB: 3E3N Livanova NB, Chebotareva NA, Eronina TB
Glycogen_phosphorylase
Mammalian protein found in humans
adenosine aminohydrolase, or ADA) is an enzyme (EC 3.5.4.4) involved in purine metabolism. It is needed for the breakdown of adenosine from food and for
Adenosine_deaminase
Central nervous system stimulant
beyond usual human consumption. Caffeine is a bitter, white crystalline purine, a methylxanthine alkaloid, and is chemically related to the adenine and
Caffeine
Chemical compound which is reduced and oxidized
Zuurendonk PF, Veech RL (1984). "Measurement of tissue purine, pyrimidine, and other nucleotides by radial compression high-performance liquid chromatography"
Nicotinamide adenine dinucleotide
Nicotinamide_adenine_dinucleotide
Chemical compound
least one phosphate group. Nucleotides contain either a purine or a pyrimidine nitrogenous base. All intermediates in purine biosynthesis are constructed
Ribose_5-phosphate
Chemical compound
antimetabolite or purine antagonist and as such inhibits DNA synthesis by inhibiting the production of the purine containing nucleotides, adenine and guanine
Mercaptopurine
Biological process
respectively. Adenine and guanine are purine nucleobases, while cytosine and thymine are pyrimidines. These nucleotides form phosphodiester bonds, creating
DNA_replication
Nucleotide containing ribose as its pentose component
nitrogenous nucleobases are derived from two parent compounds, purine and pyrimidine. Nucleotides are heterocyclic compounds, that is, they contain at least
Ribonucleotide
Drug
studied for its potential in inhibiting tumor growth by reducing purine nucleotide pools, which in turn suppresses mTORC1 activity and disrupts cancer
Pelitrexol
Medical condition
through the urea cycle to produce urea. Excess ammonia can be produced by bacterial hydrolysis of intestinal compounds, purine nucleotide cycles, the transamination
Transient hyperammonemia of the newborn
Transient_hyperammonemia_of_the_newborn
Medical condition
Exercise intolerance § low ATP reservoir Myogenic hyperuricemia Purine nucleotide cycle § pathology (low ATP reservoir, ADP>ATP, ↑AMP) Tachycardia § sinus
Inborn errors of carbohydrate metabolism
Inborn_errors_of_carbohydrate_metabolism
Enzymes that catalyze DNA formation
different mismatches. In a purine:pyrimidine mismatch there is a displacement of the pyrimidine towards the major groove and the purine towards the minor groove
DNA_polymerase
Process where substrates are converted into more complex products in living organisms
deoxyguanosine, the purine bases are attached to a deoxyribose sugar with a glycosidic bond. The purine bases on DNA and RNA nucleotides are synthesized in
Biosynthesis
RNA that facilitates the addition of amino acids to a new protein
pyrimidines and purines; for example, the amino acid glycine is coded for by the codon sequences GGU, GGC, GGA, and GGG. Other modified nucleotides may also
Transfer_RNA
Mammalian protein found in Homo sapiens
PRTase domain is homologous to many other PRTases involved in the purine nucleotide synthesis and salvage pathways. All PRTases involve the displacement
Amidophosphoribosyltransferase
Amidophosphoribosyltransferase
Immunosuppressive medication
starting point for purine nucleotide biosynthesis, while the latter is one of the building blocks of DNA and RNA. The nucleotides are incorporated into
Azathioprine
Mammalian protein found in Homo sapiens
AMP to IMP in skeletal muscle and plays an important role in the purine nucleotide cycle. Two other genes have been identified, AMPD2 and AMPD3, for the
AMP_deaminase
Redox-active coenzyme
dehydrogenase (triglyceride synthesis) and xanthine oxidase involved in purine nucleotide catabolism. Noncatalytic functions that FAD can play in flavoproteins
Flavin_adenine_dinucleotide
Chemical that inhibits the use of a metabolite
DNA production is halted and the cell dies. purine analogues – mimic the structure of metabolic purines, the larger bases incorporated into DNA as adenosine
Antimetabolite
Aromatic compound (C4H4N2)
by physico-chemical processes. RNA is composed of pyrimidine and purine nucleotides, both of which are necessary for reliable information transfer, and
Pyrimidine
Replacement, insertion, or deletion of a single DNA or RNA nucleotide
change the whole DNA sequence. Changing one purine or pyrimidine may change the amino acid that the nucleotides code for. Point mutations may arise from
Point_mutation
Chemical compound
nucleus through its bind to a nuclear transport factor, where a Guanine Nucleotide Exchange Factor Protein can come to catalyze the exchange of GTP for GDP
Guanosine_diphosphate
Cellular mechanism
53.1.577. PMID 10547702. Candeias L (1992). "Ionization of purine nucleosides and nucleotides and their components by 193-nm laser photolysis in aqueous
DNA_repair
Discovery and development of nucleoside and nucleotide reverse-transcriptase inhibitors (NRTIs and NtRTIs) began in the 1980s when the AIDS epidemic hit
Discovery and development of nucleoside and nucleotide reverse-transcriptase inhibitors
Discovery_and_development_of_nucleoside_and_nucleotide_reverse-transcriptase_inhibitors
Protein-coding gene in humans
proteins. The encoded muscle-specific enzyme plays a role in the purine nucleotide cycle by catalyzing the first step in the conversion of inosine monophosphate
ADSSL1_(gene)
Compounds in biochemical reactions
includes intermediates like inosine monophosphate (IMP), which is part of purine biosynthesis. Some can be useful in measuring rates of metabolic processes
Metabolic_intermediate
Chemical compound
archaically xanthic acid; systematic name 3,7-dihydropurine-2,6-dione) is a purine base found in most human body tissues and fluids, as well as in other organisms
Xanthine
Drug class
compared to natural nucleotides. Since many proteins depend on purine containing ligands for their function, derivatives of purine skeleton should have
Hsp90_inhibitor
– proton pump – protozoa – pseudopod – pteridophyte – Punnett square – purine – punctuated equilibrium – pyrimidine – pyruvate oxidation – quaternary
Index_of_biology_articles
Medical condition
anemia due to decreased pyrimidine synthesis, which leads to decreased nucleotide-lipid cofactors needed for erythrocyte membrane synthesis in the bone
Orotic_aciduria
Chemical compound
in animal models. It is believed to function through inhibition of purine nucleotide biosynthesis. The biosynthesis of (−)-FR901483 was elucidated by Zhang
FR901483
Linked series of chemical reactions occurring within a cell
flow in a 'cycle' wherein each component of the cycle is a substrate for the subsequent reaction in the cycle, such as in the Krebs Cycle (see below)
Metabolic_pathway
Chemical reaction
de novo synthesis of inosine monophosphate (IMP), the precursor of the purine ribonucleotides AMP and GMP. Glycinamide ribonucleotide (GAR) transformylase
Formylation
depurination The spontaneous loss of one or more purine nucleobases (either adenine or guanine) from a nucleotide or nucleic acid molecule, either DNA or RNA
Glossary of cellular and molecular biology (0–L)
Glossary_of_cellular_and_molecular_biology_(0–L)
Hypothetical stage in the early evolutionary history of life on Earth
RNA world. RNA sequences at lengths of 30 nucleotides, 60 nucleotides, 100 nucleotides, and 140 nucleotides, were capable of catalysis of "the synthesis
RNA_world
Process by which a genome changes in structure or size over time
governed by physico-chemical processes. RNA is composed of purine and pyrimidine nucleotides, both of which are necessary for reliable information transfer
Genome_evolution
Life arising from non-living matter
system cycles compounds through vent minerals, leaving little residence time to accumulate. All modern cells rely on phosphates for nucleotide backbone
Abiogenesis
Chemical process
typically synthesized through the coupling of a nucleophilic pyrimidine, purine, or other basic heterocycle with a derivative of ribose or deoxyribose that
Synthesis_of_nucleosides
Insufficient level of copper in the body, leading to anaemia and nervous symptoms
copper-dependent enzyme methionine synthase. This cycle is able to produce purines, which are a component of DNA nucleotide bases, and also myelin proteins. The spinal
Copper_deficiency
British chemist (1927–2007)
suggested an almost opposite approach, heating a mixture of ribose and the purine nucleobases hypoxanthine, adenine, and guanine to dryness in the presence
Leslie_Orgel
Chemical compound
pyrimidine and purine ribonucleosides, and RAO is a key intermediate for pyrimidine synthesis. For discussion on the synthesis pathway for purine ribonucleosides
Ribose_aminooxazoline
Class of naturally occurring chemical compounds
This group includes terpene-like and steroid-like alkaloids, as well as purine-like alkaloids such as caffeine, theobromine, theacrine and theophylline
Alkaloid
Species of true bug
genome. Through this complementation, the nucleotide requirements of both organisms are fulfilled: the purine salvage pathway is completed for A. pisum
Acyrthosiphon_pisum
Species of archaeon
non-oxidative pentose phosphate pathway (NOPPP), nucleotide metabolism, and the reductive citric acid (RTCA) cycle. Methanogenesis, the process of reducing carbon
Methanococcus_maripaludis
segments. The RNA segment contains 4 contiguous purine nucleotides. The probes should be less than 30 nucleotides in length and designed to minimize intra-probe
Cycling_probe_technology
Series of interconnected biochemical reactions
synthesis Cholesterol synthesis The citric acid cycle which in turn leads to: Amino acid synthesis Nucleotide synthesis Tetrapyrrole synthesis Although gluconeogenesis
Glycolysis
Dicarboxylic acid
and physiological conditions, the malate-aspartate shuttle or the purine nucleotide shuttle can increase mitochondrial fumarate, which is then readily
Succinic_acid
Mammalian protein found in Homo sapiens
Histone deacetylase Mismatch repair enzymes Licensing factor NKp44 receptor Nucleotide excision repair enzyme Poly ADP ribose polymerase Procaspases Protein
Proliferating cell nuclear antigen
Proliferating_cell_nuclear_antigen
Chemical compound
coffee, theophylline found in tea, or theobromine found in chocolate) have a purine structure and bind to some of the same receptors as adenosine. Methylxanthines
Adenosine
Group of simple sugar and carbohydrate compounds
citric acid cycle, fermentation, and the electron transport chain. Nucleotides are synthesized through salvage or de novo synthesis. Nucleotide salvage uses
Ribose
Chemical compound
Shirae H, Yokozeki K (1989). "Enzymatic Production of 5-Methyluridine from Purine Nucleosides and Thymine by Erwinia carotovora AJ-2992". Agricultural and
Thymidine
DNA replication in prokaryotes
that permits the formation of hydrogen bonds with the third nitrogen of purine bases and the second oxygen of pyrimidine bases. Finally, the active site
Prokaryotic_DNA_replication
RNA family
at a site between this highly conserved stem-loop and a purine rich region around 20 nucleotides downstream (the histone downstream element, or HDE). The
Histone_3′_UTR_stem-loop
Drug that inhibits activity of immune system
proliferation of both T cells and B cells. Due to their highest effectiveness, purine analogs are most frequently administered. The alkylating agents used in
Immunosuppressive_drug
Heterocyclic ligand that can complex molybdenum to form a Mo-cofactor
cofactor biosynthesis occurs in four steps: (i) the radical-mediated cyclization of nucleotide, guanosine triphosphate (GTP), to (8S)‑3',8‐cyclo‑7,8‑dihydroguanosine
Molybdopterin
Species of archaeon
This species lacks the genes for purine nucleotide biosynthesis and thus relies on environmental sources to meet its purine requirements. Sako Y, Nomura N
Aeropyrum_pernix
Subclass of purinergic P2 receptors
negatively to the presence of nucleotides in extracellular solution. Nucleotides may be divided into two categories: purines and pyrimidines. Individual
P2Y_receptor
Class of enzymes
Nucleoside-diphosphate kinases (NDPKs, also NDP kinase, (poly)nucleotide kinases and nucleoside diphosphokinases) are enzymes that catalyze the exchange
Nucleoside-diphosphate_kinase
Class of enzymes
RNA primer, Pol α starts replication elongating the primer with ~20 nucleotides. In addition to its role during DNA replication, POLA1 plays a role in
DNA polymerase alpha catalytic subunit
DNA_polymerase_alpha_catalytic_subunit
Protein-coding gene in the species Homo sapiens
releasing the damaged base and creating an AP site– a site that lacks a purine or pyrimidine base. In the next step, an AP endonuclease creates a nick
DNA_ligase_1
Hexameric enzyme
3–24. Frieden C (May 1965). "Glutamate Dehydrogenase. VI. Survey of Purine Nucleotide and Other Effects on the Enzyme from Various Sources". The Journal
Glutamate_dehydrogenase
observed that purine-pyrimidine transversions occurred at a high frequency among the SNPs. The characterization of copy number and single nucleotide variations
MALBAC
Damage to the structure of a biological molecule
dysfunction. Depurination is caused by hydrolysis and results in loss of the purine base of a nucleic acid. DNA is more prone to this, as the transition state
Molecular_lesion
a purine nucleotide is substituted for a pyrimidine nucleotide, or vice versa (e.g. A ↔ C or A ↔ T). Contrast transition. tricarboxylic acid cycle (TCA)
Glossary of cellular and molecular biology (M–Z)
Glossary_of_cellular_and_molecular_biology_(M–Z)
Type of genetic component
binds to the terminus of nucleic acids. The second coding region has a purine/pyrimidine nuclease, reverse transcriptase and protein rich in amino acids
Retrotransposon
PURINE NUCLEOTIDE-CYCLE
PURINE NUCLEOTIDE-CYCLE
Girl/Female
Spanish
White.
Female
English
Variant spelling of English Doreen, DORINE means "gift."Â
Female
English
English pet form of Latin Laura, LAURINE means "laurel."
Girl/Female
Irish
muirne means “high-spirited, festive.†Muirne loved Conall who was from an opposing tribe. Her father, a druid, opposed the match and had Conall killed but not before Muirne had conceived a son, who grew up to be the legendary warrior Fionn Mac Cool(read the legend) and who later avenged the death of his father.
Male
Italian
Italian form of Greek Paris, probably PARIDE means "wager."Â
Female
Gaelic
Old Gaelic name MUIRNE means "beloved."
Female
French
Feminine form of French Marin, MARINE means "of the sea."
Female
English
Variant spelling of English Careen, CARINE means "beloved" or "friend."Â
Female
French
French feminine form of Roman Latin Zephyrinus, ZÉPHYRINE means "west wind."
Female
English
Pet form of English Perdita, PURDIE means "lost."
Male
English
English name derived from the title, prince, from Latin princeps, PRINCE means "chief, first."Â
Boy/Male
Indian, Modern
Purity
Female
English
French form of Latin Paulina, PAULINE means "small."
Girl/Female
British, English
Purity
Female
Greek
(ΜυÏίνη) Variant spelling of Greek Myrina, possibly MYRINE means "swiftly bounding."
Female
French
Variant spelling of French Corinne, CORINE means "maiden."
Surname or Lastname
English and French
English and French : nickname from Middle English, Old French prince (Latin princeps), presumably denoting someone who behaved in a regal manner or who had won the title in some contest of skill.Translation of German and Ashkenazic Jewish Prinz or of a word meaning ‘prince’ in some other language.
Female
English
Variant spelling of English Maureen, MAURINE means "obstinacy, rebelliousness" or "their rebellion."
Female
French
Feminine form of French Perrin, PERRINE means "rock, stone."
Boy/Male
Latin American English
Prince.
PURINE NUCLEOTIDE-CYCLE
PURINE NUCLEOTIDE-CYCLE
Girl/Female
British, Hindu, Indian
Beautiful
Girl/Female
Tamil
Captivating
Girl/Female
American, Australian
Victorious People
Boy/Male
British, Christian, English, Scandinavian
Divine Spear; Diminutive of Oswald
Girl/Female
Greek
A Harpy.
Girl/Female
Indian, Tamil
Name of a Flower
Boy/Male
Hindu
Surname or Lastname
English
English : variant of Siddons.
Girl/Female
Latin
From the Tigris.
Boy/Male
Welsh
Legendary son of Beli.
PURINE NUCLEOTIDE-CYCLE
PURINE NUCLEOTIDE-CYCLE
PURINE NUCLEOTIDE-CYCLE
PURINE NUCLEOTIDE-CYCLE
PURINE NUCLEOTIDE-CYCLE
a.
Of or pertaining to the apostle Paul, or his writings; resembling, or conforming to, the writings of Paul; as, the Pauline epistles; Pauline doctrine.
a.
The sum of naval affairs; naval economy; the department of navigation and sea forces; the collective shipping of a country; as, the mercantile marine.
v. t.
To make pure or clear from material defilement, admixture, or imperfection; to free from extraneous or noxious matter; as, to purify liquors or metals; to purify the blood; to purify the air.
n.
One who aims at excessive purity or nicety, esp. in the choice of language.
v. t.
Hence, in figurative uses: (a) To free from guilt or moral defilement; as, to purify the heart.
n.
In root construction, a horizontal member supported on the principals and supporting the common rafters.
a.
Wild; untamed; savage; as, lions, tigers, wolves, and bears are ferine beasts.
a.
Younger or inferior in rank; junior; associate; as, a chief justice and three puisne justices of the Court of Common Pleas; the puisne barons of the Court of Exchequer.
v. i.
To play the prince.
a.
A picture representing some marine subject.
v. t.
To free from improprieties or barbarisms; as, to purify a language.
a.
Of or pertaining to the sea; having to do with the ocean, or with navigation or naval affairs; nautical; as, marine productions or bodies; marine shells; a marine engine.
prep.
In the time of; as long as the action or existence of; as, during life; during the space of a year.
a.
Formed by the action of the currents or waves of the sea; as, marine deposits.
n.
One of a tribe of rodents, of which the mouse is the type.
v. t.
To decorate with a wrought or flowered border; to embroider; to ornament with metallic threads; as, to purfle with blue and white.
a.
Of or pertaining to St.Peter; as, the Petrine Epistles.
a.
The chief of any body of men; one at the head of a class or profession; one who is preeminent; as, a merchant prince; a prince of players.
n.
Rigid purity; the quality of being affectedly pure or nice, especially in the choice of language; over-solicitude as to purity.