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NIVASOREXANT

• Nivasorexant

Chemical compound

Nivasorexant (INNTooltip International Nonproprietary Name; developmental code name ACT-539313) is an orexin receptor antagonist which is under development

Nivasorexant



Nivasorexant

• Orexin antagonist

Class of drugs

approved for insomnia in Japan in August 2025 – half-life 1.5–3 hours Nivasorexant (ACT-539313) – selective OX1 antagonist – under development for binge

Orexin antagonist

Orexin_antagonist

• Alixorexton

Novel chemistry compound

Fazamorexant (YZJ-1139) Filorexant GSK-649868 (SB-649868) Lemborexant Nivasorexant (ACT-539313) Rocavorexant (C4X-3256; INDV-2000 RTIOX-276 SB-334867 SB-408124

Alixorexton



Alixorexton

• Oveporexton

Medication

Fazamorexant (YZJ-1139) Filorexant GSK-649868 (SB-649868) Lemborexant Nivasorexant (ACT-539313) Rocavorexant (C4X-3256; INDV-2000 RTIOX-276 SB-334867 SB-408124

Oveporexton



Oveporexton

• Orexin receptor

G-protein-coupled receptor

receptor antagonist JNJ-10397049 – selective OX2 receptor antagonist Nivasorexant (ACT-539313) – selective OX1 receptor antagonist Rocavorexant (C4X-3256;

Orexin receptor

Orexin_receptor

• Lemborexant

Insomnia medication

Fazamorexant (YZJ-1139) Filorexant GSK-649868 (SB-649868) Lemborexant Nivasorexant (ACT-539313) Rocavorexant (C4X-3256; INDV-2000 RTIOX-276 SB-334867 SB-408124

Lemborexant



Lemborexant

• Daridorexant

Medication used to treat insomnia

Fazamorexant (YZJ-1139) Filorexant GSK-649868 (SB-649868) Lemborexant Nivasorexant (ACT-539313) Rocavorexant (C4X-3256; INDV-2000 RTIOX-276 SB-334867 SB-408124

Daridorexant



Daridorexant

• Suvorexant

Medication used to treat insomnia

Fazamorexant (YZJ-1139) Filorexant GSK-649868 (SB-649868) Lemborexant Nivasorexant (ACT-539313) Rocavorexant (C4X-3256; INDV-2000 RTIOX-276 SB-334867 SB-408124

Suvorexant



Suvorexant

• Orexin

Neuropeptide that regulates arousal, wakefulness, and appetite

Fazamorexant (YZJ-1139) Filorexant GSK-649868 (SB-649868) Lemborexant Nivasorexant (ACT-539313) Rocavorexant (C4X-3256; INDV-2000 RTIOX-276 SB-334867 SB-408124

Orexin



Orexin

• Almorexant

Orexin antagonist compound

Fazamorexant (YZJ-1139) Filorexant GSK-649868 (SB-649868) Lemborexant Nivasorexant (ACT-539313) Rocavorexant (C4X-3256; INDV-2000 RTIOX-276 SB-334867 SB-408124

Almorexant



Almorexant

• Firazorexton

Chemical compound

Fazamorexant (YZJ-1139) Filorexant GSK-649868 (SB-649868) Lemborexant Nivasorexant (ACT-539313) Rocavorexant (C4X-3256; INDV-2000 RTIOX-276 SB-334867 SB-408124

Firazorexton



Firazorexton

• Seltorexant

Experimental anti-insomnia drug

Fazamorexant (YZJ-1139) Filorexant GSK-649868 (SB-649868) Lemborexant Nivasorexant (ACT-539313) Rocavorexant (C4X-3256; INDV-2000 RTIOX-276 SB-334867 SB-408124

Seltorexant



Seltorexant

• Danavorexton

Chemical compound

Fazamorexant (YZJ-1139) Filorexant GSK-649868 (SB-649868) Lemborexant Nivasorexant (ACT-539313) Rocavorexant (C4X-3256; INDV-2000 RTIOX-276 SB-334867 SB-408124

Danavorexton



Danavorexton

• Cleminorexton

Pharmaceutical compound

Fazamorexant (YZJ-1139) Filorexant GSK-649868 (SB-649868) Lemborexant Nivasorexant (ACT-539313) Rocavorexant (C4X-3256; INDV-2000 RTIOX-276 SB-334867 SB-408124

Cleminorexton



Cleminorexton

• Filorexant

Chemical compound

Fazamorexant (YZJ-1139) Filorexant GSK-649868 (SB-649868) Lemborexant Nivasorexant (ACT-539313) Rocavorexant (C4X-3256; INDV-2000 RTIOX-276 SB-334867 SB-408124

Filorexant



Filorexant

• Orexin-A

Stimulating neuropeptide

Fazamorexant (YZJ-1139) Filorexant GSK-649868 (SB-649868) Lemborexant Nivasorexant (ACT-539313) Rocavorexant (C4X-3256; INDV-2000 RTIOX-276 SB-334867 SB-408124

Orexin-A

Orexin-A

• Tebideutorexant

Chemical compound

Fazamorexant (YZJ-1139) Filorexant GSK-649868 (SB-649868) Lemborexant Nivasorexant (ACT-539313) Rocavorexant (C4X-3256; INDV-2000 RTIOX-276 SB-334867 SB-408124

Tebideutorexant



Tebideutorexant

• List of investigational anxiety disorder drugs

Investigational anxiety disorder drugs

GABAA receptor positive allosteric modulator and benzodiazepine [108] Nivasorexant (ACT-539313; SORA) – orexin OX1 receptor antagonist [109] NS-11821 (NS11821)

List of investigational anxiety disorder drugs

List_of_investigational_anxiety_disorder_drugs

• Balumorexton

Pharmaceutical compound

Fazamorexant (YZJ-1139) Filorexant GSK-649868 (SB-649868) Lemborexant Nivasorexant (ACT-539313) Rocavorexant (C4X-3256; INDV-2000 RTIOX-276 SB-334867 SB-408124

Balumorexton



Balumorexton

• Ledasorexton

Pharmaceutical compound

Fazamorexant (YZJ-1139) Filorexant GSK-649868 (SB-649868) Lemborexant Nivasorexant (ACT-539313) Rocavorexant (C4X-3256; INDV-2000 RTIOX-276 SB-334867 SB-408124

Ledasorexton



Ledasorexton

• Fazamorexant

Orexin receptor antagonist

Fazamorexant (YZJ-1139) Filorexant GSK-649868 (SB-649868) Lemborexant Nivasorexant (ACT-539313) Rocavorexant (C4X-3256; INDV-2000 RTIOX-276 SB-334867 SB-408124

Fazamorexant



Fazamorexant

• Suntinorexton

Chemical compound

Fazamorexant (YZJ-1139) Filorexant GSK-649868 (SB-649868) Lemborexant Nivasorexant (ACT-539313) Rocavorexant (C4X-3256; INDV-2000 RTIOX-276 SB-334867 SB-408124

Suntinorexton



Suntinorexton

• SB-649868

Chemical compound

Fazamorexant (YZJ-1139) Filorexant GSK-649868 (SB-649868) Lemborexant Nivasorexant (ACT-539313) Rocavorexant (C4X-3256; INDV-2000 RTIOX-276 SB-334867 SB-408124

SB-649868



SB-649868

• Vornorexant

Chemical compound

Fazamorexant (YZJ-1139) Filorexant GSK-649868 (SB-649868) Lemborexant Nivasorexant (ACT-539313) Rocavorexant (C4X-3256; INDV-2000 RTIOX-276 SB-334867 SB-408124

Vornorexant



Vornorexant

• SB-408124

Chemical compound

Fazamorexant (YZJ-1139) Filorexant GSK-649868 (SB-649868) Lemborexant Nivasorexant (ACT-539313) Rocavorexant (C4X-3256; INDV-2000 RTIOX-276 SB-334867 SB-408124

SB-408124



SB-408124

• List of investigational eating disorder drugs

Investigational eating disorder drugs

spray; OPNT-001) – μ-opioid receptor antagonist – eating disorders [5] Nivasorexant (ACT-539313; SORA) – orexin OX1 receptor antagonist – binge-eating disorder

List of investigational eating disorder drugs

List_of_investigational_eating_disorder_drugs

• EMPA (drug)

Chemical compound

Fazamorexant (YZJ-1139) Filorexant GSK-649868 (SB-649868) Lemborexant Nivasorexant (ACT-539313) Rocavorexant (C4X-3256; INDV-2000 RTIOX-276 SB-334867 SB-408124

EMPA (drug)



EMPA_(drug)

• Orexin receptor type 2

Protein-coding gene in the species Homo sapiens

Fazamorexant (YZJ-1139) Filorexant GSK-649868 (SB-649868) Lemborexant Nivasorexant (ACT-539313) Rocavorexant (C4X-3256; INDV-2000 RTIOX-276 SB-334867 SB-408124

Orexin receptor type 2



Orexin_receptor_type_2

• Rocavorexant

Pharmaceutical compound

Fazamorexant (YZJ-1139) Filorexant GSK-649868 (SB-649868) Lemborexant Nivasorexant (ACT-539313) Rocavorexant (C4X-3256; INDV-2000 RTIOX-276 SB-334867 SB-408124

Rocavorexant



Rocavorexant

• TCS-OX2-29

Orexin antagonist

Fazamorexant (YZJ-1139) Filorexant GSK-649868 (SB-649868) Lemborexant Nivasorexant (ACT-539313) Rocavorexant (C4X-3256; INDV-2000 RTIOX-276 SB-334867 SB-408124

TCS-OX2-29



TCS-OX2-29

• Hypocretin (orexin) receptor 1

Protein found in humans

Fazamorexant (YZJ-1139) Filorexant GSK-649868 (SB-649868) Lemborexant Nivasorexant (ACT-539313) Rocavorexant (C4X-3256; INDV-2000 RTIOX-276 SB-334867 SB-408124

Hypocretin (orexin) receptor 1



Hypocretin_(orexin)_receptor_1

• RTIOX-276

Orexin antagonist

Fazamorexant (YZJ-1139) Filorexant GSK-649868 (SB-649868) Lemborexant Nivasorexant (ACT-539313) Rocavorexant (C4X-3256; INDV-2000 RTIOX-276 SB-334867 SB-408124

RTIOX-276



RTIOX-276

• SB-334867

Chemical compound

Fazamorexant (YZJ-1139) Filorexant GSK-649868 (SB-649868) Lemborexant Nivasorexant (ACT-539313) Rocavorexant (C4X-3256; INDV-2000 RTIOX-276 SB-334867 SB-408124

SB-334867



SB-334867

• ACT-335827

Chemical compound

Fazamorexant (YZJ-1139) Filorexant GSK-649868 (SB-649868) Lemborexant Nivasorexant (ACT-539313) Rocavorexant (C4X-3256; INDV-2000 RTIOX-276 SB-334867 SB-408124

ACT-335827



ACT-335827

• JNJ-10397049

Chemical compound

Fazamorexant (YZJ-1139) Filorexant GSK-649868 (SB-649868) Lemborexant Nivasorexant (ACT-539313) Rocavorexant (C4X-3256; INDV-2000 RTIOX-276 SB-334867 SB-408124

JNJ-10397049



JNJ-10397049

• ACT-462206

Chemical compound

Fazamorexant (YZJ-1139) Filorexant GSK-649868 (SB-649868) Lemborexant Nivasorexant (ACT-539313) Rocavorexant (C4X-3256; INDV-2000 RTIOX-276 SB-334867 SB-408124

ACT-462206



ACT-462206

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NIVASOREXANT

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NIVASOREXANT

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NIVASOREXANT

Affordable travel, tourism, home and auto insurance, legal services

travel, tourism, insurance

• Travel & tourism
• Home Insurance
• Auto Insurance
• Online Shopping
• Personal Injury Lawyer
• Dui Attorney
• Mesothelioma Lawsuit
• Car Insurance Quotes
• Mortgage Rates
• Life Insurance Comparison
• Insurance Policy
• Bankruptcy Lawyer
• Injury Lawyers
• Consolidate-personal-loans
• Loans
• personal-loans
• Weightloss Medication
• Check Credit Score
• Accident Lawyers
• Cheap Insurance
• Private Jet Charter Rates
• Cheap Flights
• Structured Settlements
• Rehab Facilities
• Video Conferencing
• Loans & Mortgages
• Charter Flights
• Health & Fitness
• Digital Marketing
• Wrongful Death Lawyers
• Mortgage Refinancing
• Best Online Advertising
• Online Degrees
• Shop Online
• Flight Deals
• Enterprise CRM
• Cyber Security Software
• Life Insurance Comparison
• Best Credit Cards
• Forex Trading Platform
• Crypto Trading
• Cloud Hosting
• Enterprise AI Platforms
• VPN Apps
• Online MBA Programs
• Coding Bootcamps
• Online College Business Degree