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NEUROD

  • NeuroD
  • Basic helix-loop-helix transcription factor

    NeuroD, also called Beta2, is a basic helix-loop-helix transcription factor expressed in certain parts of brain, pancreatic beta cells and enteroendocrine

    NeuroD

    NeuroD

  • NEUROD1
  • Protein-coding gene in the species Homo sapiens

    differentiation 1 (Neurod1), also called β2, is a transcription factor of the NeuroD-type. It is encoded by the human gene NEUROD1. In mice, Neurod1 expression

    NEUROD1

    NEUROD1

    NEUROD1

  • Neurogenins
  • Protein family

    differentiation also expressed during early neural development include NeuroD and ASCL1. Neurogenins primarily govern the transition of neural progenitor

    Neurogenins

    Neurogenins

  • NEUROD2
  • Protein-coding gene in the species Homo sapiens

    humans is encoded by the NEUROD2 gene. This gene encodes a member of the neuroD family of neurogenic basic helix-loop-helix (bHLH) proteins. Expression

    NEUROD2

    NEUROD2

    NEUROD2

  • Neurogenin-1
  • Protein-coding gene

    expression patterns and transcriptional activation potentials within the neuroD gene family". Molecular and Cellular Biology. 16 (10): 5792–800. doi:10

    Neurogenin-1

    Neurogenin-1

    Neurogenin-1

  • Developmental biology
  • Study of how organisms develop and grow

    sequences in the DNA in order to activate gene expression. For example, NeuroD is a key transcription factor for neuronal differentiation, myogenin for

    Developmental biology

    Developmental_biology

  • Insulin
  • Peptide hormone

    factors. In general, the A-boxes bind to Pdx1 factors, E-boxes bind to NeuroD, C-boxes bind to MafA, and cAMP response elements to CREB. There are also

    Insulin

    Insulin

    Insulin

  • Basic helix–loop–helix
  • Protein structural motif

    Scl, also known as Tal1 proneural bHLH genes like p-CaMKII, and pSer(336)NeuroD. Neurogenins MAX C-Myc, N-Myc TCF4 (Transcription Factor 4) These proteins

    Basic helix–loop–helix

    Basic helix–loop–helix

    Basic_helix–loop–helix

  • P53
  • Mammalian protein found in humans

    ATOH1 HAND 1 2 MESP2 Myogenic regulatory factors MyoD Myogenin MYF5 MYF6 NeuroD 1 2 Neurogenins 1 2 3 OLIG 1 2 Paraxis TCF15 Scleraxis SLC LYL1 TAL 1 2

    P53

    P53

    P53

  • Sex-determining region Y protein
  • Protein that initiates male sex determination in therian mammals

    ATOH1 HAND 1 2 MESP2 Myogenic regulatory factors MyoD Myogenin MYF5 MYF6 NeuroD 1 2 Neurogenins 1 2 3 OLIG 1 2 Paraxis TCF15 Scleraxis SLC LYL1 TAL 1 2

    Sex-determining region Y protein

    Sex-determining region Y protein

    Sex-determining_region_Y_protein

  • Receptor (biochemistry)
  • Protein molecule receiving signals for a cell

    ATOH1 HAND 1 2 MESP2 Myogenic regulatory factors MyoD Myogenin MYF5 MYF6 NeuroD 1 2 Neurogenins 1 2 3 OLIG 1 2 Paraxis TCF15 Scleraxis SLC LYL1 TAL 1 2

    Receptor (biochemistry)

    Receptor (biochemistry)

    Receptor_(biochemistry)

  • Pancreatic progenitor cell
  • Type of stem cell

    suppression of Notch signaling. Pancreatic Progenitor cells are hence Ngn3+/NeuroD+/IA1+/Isl1+/Pax6+ cells. These cells then develop into Beta cell pro-precursors

    Pancreatic progenitor cell

    Pancreatic progenitor cell

    Pancreatic_progenitor_cell

  • Transcription factor
  • Protein that regulates the rate of DNA transcription

    ATOH1 HAND 1 2 MESP2 Myogenic regulatory factors MyoD Myogenin MYF5 MYF6 NeuroD 1 2 Neurogenins 1 2 3 OLIG 1 2 Paraxis TCF15 Scleraxis SLC LYL1 TAL 1 2

    Transcription factor

    Transcription factor

    Transcription_factor

  • FOXP2
  • Transcription factor gene of the forkhead box family

    ATOH1 HAND 1 2 MESP2 Myogenic regulatory factors MyoD Myogenin MYF5 MYF6 NeuroD 1 2 Neurogenins 1 2 3 OLIG 1 2 Paraxis TCF15 Scleraxis SLC LYL1 TAL 1 2

    FOXP2

    FOXP2

    FOXP2

  • NFE2L2
  • Human protein and coding gene

    ATOH1 HAND 1 2 MESP2 Myogenic regulatory factors MyoD Myogenin MYF5 MYF6 NeuroD 1 2 Neurogenins 1 2 3 OLIG 1 2 Paraxis TCF15 Scleraxis SLC LYL1 TAL 1 2

    NFE2L2

    NFE2L2

    NFE2L2

  • Karlsbad (Baden)
  • Municipality in Baden-Württemberg, Germany

    joined the former single-village municipality Reichenbach: Etzenrot and Neurod (joined in 1971) Busenbach (joined in 1972) In 1974 the enlarged municipality

    Karlsbad (Baden)

    Karlsbad (Baden)

    Karlsbad_(Baden)

  • Myc
  • Family of regulator genes

    ATOH1 HAND 1 2 MESP2 Myogenic regulatory factors MyoD Myogenin MYF5 MYF6 NeuroD 1 2 Neurogenins 1 2 3 OLIG 1 2 Paraxis TCF15 Scleraxis SLC LYL1 TAL 1 2

    Myc

    Myc

  • Mir-190 microRNA precursor family
  • Short RNA molecule

    Zheng H, Zeng Y, Chu J, Kam AY, Loh HH, Law PY (June 2010). "Modulations of NeuroD activity contribute to the differential effects of morphine and fentanyl

    Mir-190 microRNA precursor family

    Mir-190_microRNA_precursor_family

  • NF-κB
  • Family of transcription factor protein complexes

    ATOH1 HAND 1 2 MESP2 Myogenic regulatory factors MyoD Myogenin MYF5 MYF6 NeuroD 1 2 Neurogenins 1 2 3 OLIG 1 2 Paraxis TCF15 Scleraxis SLC LYL1 TAL 1 2

    NF-κB

    NF-κB

    NF-κB

  • Transcription factor Sp3
  • Protein-coding gene in the species Homo sapiens

    ATOH1 HAND 1 2 MESP2 Myogenic regulatory factors MyoD Myogenin MYF5 MYF6 NeuroD 1 2 Neurogenins 1 2 3 OLIG 1 2 Paraxis TCF15 Scleraxis SLC LYL1 TAL 1 2

    Transcription factor Sp3

    Transcription factor Sp3

    Transcription_factor_Sp3

  • Estrogen receptor
  • Proteins activated by the hormone estrogen

    ATOH1 HAND 1 2 MESP2 Myogenic regulatory factors MyoD Myogenin MYF5 MYF6 NeuroD 1 2 Neurogenins 1 2 3 OLIG 1 2 Paraxis TCF15 Scleraxis SLC LYL1 TAL 1 2

    Estrogen receptor

    Estrogen receptor

    Estrogen_receptor

  • Peroxisome proliferator-activated receptor gamma
  • Nuclear receptor protein found in humans

    ATOH1 HAND 1 2 MESP2 Myogenic regulatory factors MyoD Myogenin MYF5 MYF6 NeuroD 1 2 Neurogenins 1 2 3 OLIG 1 2 Paraxis TCF15 Scleraxis SLC LYL1 TAL 1 2

    Peroxisome proliferator-activated receptor gamma

    Peroxisome proliferator-activated receptor gamma

    Peroxisome_proliferator-activated_receptor_gamma

  • Nuclear receptor
  • Protein

    ATOH1 HAND 1 2 MESP2 Myogenic regulatory factors MyoD Myogenin MYF5 MYF6 NeuroD 1 2 Neurogenins 1 2 3 OLIG 1 2 Paraxis TCF15 Scleraxis SLC LYL1 TAL 1 2

    Nuclear receptor

    Nuclear receptor

    Nuclear_receptor

  • Peroxisome proliferator-activated receptor
  • Group of nuclear receptor proteins

    ATOH1 HAND 1 2 MESP2 Myogenic regulatory factors MyoD Myogenin MYF5 MYF6 NeuroD 1 2 Neurogenins 1 2 3 OLIG 1 2 Paraxis TCF15 Scleraxis SLC LYL1 TAL 1 2

    Peroxisome proliferator-activated receptor

    Peroxisome proliferator-activated receptor

    Peroxisome_proliferator-activated_receptor

  • Heterochromatin protein 1
  • Protein family

    ATOH1 HAND 1 2 MESP2 Myogenic regulatory factors MyoD Myogenin MYF5 MYF6 NeuroD 1 2 Neurogenins 1 2 3 OLIG 1 2 Paraxis TCF15 Scleraxis SLC LYL1 TAL 1 2

    Heterochromatin protein 1

    Heterochromatin_protein_1

  • FOX proteins
  • Family of transcription factors involved in anatomical development

    ATOH1 HAND 1 2 MESP2 Myogenic regulatory factors MyoD Myogenin MYF5 MYF6 NeuroD 1 2 Neurogenins 1 2 3 OLIG 1 2 Paraxis TCF15 Scleraxis SLC LYL1 TAL 1 2

    FOX proteins

    FOX proteins

    FOX_proteins

  • FOSB
  • Protein

    ATOH1 HAND 1 2 MESP2 Myogenic regulatory factors MyoD Myogenin MYF5 MYF6 NeuroD 1 2 Neurogenins 1 2 3 OLIG 1 2 Paraxis TCF15 Scleraxis SLC LYL1 TAL 1 2

    FOSB

    FOSB

    FOSB

  • SOX2
  • Transcription factor gene of the SOX family

    ATOH1 HAND 1 2 MESP2 Myogenic regulatory factors MyoD Myogenin MYF5 MYF6 NeuroD 1 2 Neurogenins 1 2 3 OLIG 1 2 Paraxis TCF15 Scleraxis SLC LYL1 TAL 1 2

    SOX2

    SOX2

    SOX2

  • Homeobox
  • DNA pattern affecting anatomy development

    ATOH1 HAND 1 2 MESP2 Myogenic regulatory factors MyoD Myogenin MYF5 MYF6 NeuroD 1 2 Neurogenins 1 2 3 OLIG 1 2 Paraxis TCF15 Scleraxis SLC LYL1 TAL 1 2

    Homeobox

    Homeobox

    Homeobox

  • Eomesodermin
  • Protein-coding gene in the species Homo sapiens

    subventricular zone. The IPCs then undergo symmetric division to produce NeuroD expressing cells that can differentiate in TBR1 neurons. Similar mechanisms

    Eomesodermin

    Eomesodermin

    Eomesodermin

  • FOXO3
  • Protein-coding gene in humans

    ATOH1 HAND 1 2 MESP2 Myogenic regulatory factors MyoD Myogenin MYF5 MYF6 NeuroD 1 2 Neurogenins 1 2 3 OLIG 1 2 Paraxis TCF15 Scleraxis SLC LYL1 TAL 1 2

    FOXO3

    FOXO3

    FOXO3

  • Peroxisome proliferator-activated receptor delta
  • Nuclear receptor protein found in humans

    ATOH1 HAND 1 2 MESP2 Myogenic regulatory factors MyoD Myogenin MYF5 MYF6 NeuroD 1 2 Neurogenins 1 2 3 OLIG 1 2 Paraxis TCF15 Scleraxis SLC LYL1 TAL 1 2

    Peroxisome proliferator-activated receptor delta

    Peroxisome proliferator-activated receptor delta

    Peroxisome_proliferator-activated_receptor_delta

  • GSX2
  • ATOH1 HAND 1 2 MESP2 Myogenic regulatory factors MyoD Myogenin MYF5 MYF6 NeuroD 1 2 Neurogenins 1 2 3 OLIG 1 2 Paraxis TCF15 Scleraxis SLC LYL1 TAL 1 2

    GSX2

    GSX2

    GSX2

  • Peroxisome proliferator-activated receptor alpha
  • Nuclear receptor protein found in humans

    ATOH1 HAND 1 2 MESP2 Myogenic regulatory factors MyoD Myogenin MYF5 MYF6 NeuroD 1 2 Neurogenins 1 2 3 OLIG 1 2 Paraxis TCF15 Scleraxis SLC LYL1 TAL 1 2

    Peroxisome proliferator-activated receptor alpha

    Peroxisome proliferator-activated receptor alpha

    Peroxisome_proliferator-activated_receptor_alpha

  • HES1
  • Protein-coding gene in the species Homo sapiens

    ATOH1 HAND 1 2 MESP2 Myogenic regulatory factors MyoD Myogenin MYF5 MYF6 NeuroD 1 2 Neurogenins 1 2 3 OLIG 1 2 Paraxis TCF15 Scleraxis SLC LYL1 TAL 1 2

    HES1

    HES1

    HES1

  • Progesterone receptor
  • Cytoplasmic receptor protein found inside cells

    ATOH1 HAND 1 2 MESP2 Myogenic regulatory factors MyoD Myogenin MYF5 MYF6 NeuroD 1 2 Neurogenins 1 2 3 OLIG 1 2 Paraxis TCF15 Scleraxis SLC LYL1 TAL 1 2

    Progesterone receptor

    Progesterone receptor

    Progesterone_receptor

  • Ci protein
  • Zinc finger containing transcription factor

    ATOH1 HAND 1 2 MESP2 Myogenic regulatory factors MyoD Myogenin MYF5 MYF6 NeuroD 1 2 Neurogenins 1 2 3 OLIG 1 2 Paraxis TCF15 Scleraxis SLC LYL1 TAL 1 2

    Ci protein

    Ci_protein

  • CREB
  • Class of proteins

    ATOH1 HAND 1 2 MESP2 Myogenic regulatory factors MyoD Myogenin MYF5 MYF6 NeuroD 1 2 Neurogenins 1 2 3 OLIG 1 2 Paraxis TCF15 Scleraxis SLC LYL1 TAL 1 2

    CREB

    CREB

    CREB

  • Retinoblastoma protein
  • Mammalian protein found in humans

    ATOH1 HAND 1 2 MESP2 Myogenic regulatory factors MyoD Myogenin MYF5 MYF6 NeuroD 1 2 Neurogenins 1 2 3 OLIG 1 2 Paraxis TCF15 Scleraxis SLC LYL1 TAL 1 2

    Retinoblastoma protein

    Retinoblastoma protein

    Retinoblastoma_protein

  • OLIG2
  • Protein found in humans

    ATOH1 HAND 1 2 MESP2 Myogenic regulatory factors MyoD Myogenin MYF5 MYF6 NeuroD 1 2 Neurogenins 1 2 3 OLIG 1 2 Paraxis TCF15 Scleraxis SLC LYL1 TAL 1 2

    OLIG2

    OLIG2

    OLIG2

  • Muse cell
  • Endogenous non-cancerous pluripotent stem cell

    Muse cells can differentiate into: Ectodermal- (cells positive for nestin, NeuroD, Musashi, neurofilament, MAP-2, melanocyte markers (tyrosinase, MITF, gf100

    Muse cell

    Muse_cell

  • Neurogenin-3
  • Mammalian protein found in Homo sapiens

    precursors. In the absence of Neurogenin-3, expression of ISL1, PAX4, PAX6, and NeuroD are lost and endocrine precursors are lacking in the pancreatic epithelium

    Neurogenin-3

    Neurogenin-3

    Neurogenin-3

  • RING1
  • Protein-coding gene in the species Homo sapiens

    ATOH1 HAND 1 2 MESP2 Myogenic regulatory factors MyoD Myogenin MYF5 MYF6 NeuroD 1 2 Neurogenins 1 2 3 OLIG 1 2 Paraxis TCF15 Scleraxis SLC LYL1 TAL 1 2

    RING1

    RING1

    RING1

  • Proneural genes
  • For example, in Xenopus, Chitnis and Kintner demonstrated that XASH-3 and NeuroD (achaete-scute complex) respond differently to lateral inhibition, which

    Proneural genes

    Proneural_genes

  • Kristen Kroll
  • American developmental biologist

    required for vertebrate neurogenesis and mediates transactivation of Ngn and NeuroD". Development. 132 (1). The Company of Biologists: 105–115. doi:10.1242/dev

    Kristen Kroll

    Kristen_Kroll

  • Androgen receptor
  • Mammalian protein found in humans

    ATOH1 HAND 1 2 MESP2 Myogenic regulatory factors MyoD Myogenin MYF5 MYF6 NeuroD 1 2 Neurogenins 1 2 3 OLIG 1 2 Paraxis TCF15 Scleraxis SLC LYL1 TAL 1 2

    Androgen receptor

    Androgen receptor

    Androgen_receptor

  • HIF1A
  • Protein-coding gene in the species Homo sapiens

    ATOH1 HAND 1 2 MESP2 Myogenic regulatory factors MyoD Myogenin MYF5 MYF6 NeuroD 1 2 Neurogenins 1 2 3 OLIG 1 2 Paraxis TCF15 Scleraxis SLC LYL1 TAL 1 2

    HIF1A

    HIF1A

    HIF1A

  • Aryl hydrocarbon receptor
  • Vertebrate receptor protein and transcription factor

    ATOH1 HAND 1 2 MESP2 Myogenic regulatory factors MyoD Myogenin MYF5 MYF6 NeuroD 1 2 Neurogenins 1 2 3 OLIG 1 2 Paraxis TCF15 Scleraxis SLC LYL1 TAL 1 2

    Aryl hydrocarbon receptor

    Aryl hydrocarbon receptor

    Aryl_hydrocarbon_receptor

  • FOXP3
  • Immune response protein

    ATOH1 HAND 1 2 MESP2 Myogenic regulatory factors MyoD Myogenin MYF5 MYF6 NeuroD 1 2 Neurogenins 1 2 3 OLIG 1 2 Paraxis TCF15 Scleraxis SLC LYL1 TAL 1 2

    FOXP3

    FOXP3

    FOXP3

  • Hypoxia-inducible factor
  • Protein that responds to low oxygen

    ATOH1 HAND 1 2 MESP2 Myogenic regulatory factors MyoD Myogenin MYF5 MYF6 NeuroD 1 2 Neurogenins 1 2 3 OLIG 1 2 Paraxis TCF15 Scleraxis SLC LYL1 TAL 1 2

    Hypoxia-inducible factor

    Hypoxia-inducible_factor

  • T-box transcription factor T
  • Protein-coding gene in the species Homo sapiens

    ATOH1 HAND 1 2 MESP2 Myogenic regulatory factors MyoD Myogenin MYF5 MYF6 NeuroD 1 2 Neurogenins 1 2 3 OLIG 1 2 Paraxis TCF15 Scleraxis SLC LYL1 TAL 1 2

    T-box transcription factor T

    T-box transcription factor T

    T-box_transcription_factor_T

  • Transcription factor Jun
  • Mammalian protein found in Homo sapiens

    ATOH1 HAND 1 2 MESP2 Myogenic regulatory factors MyoD Myogenin MYF5 MYF6 NeuroD 1 2 Neurogenins 1 2 3 OLIG 1 2 Paraxis TCF15 Scleraxis SLC LYL1 TAL 1 2

    Transcription factor Jun

    Transcription factor Jun

    Transcription_factor_Jun

  • Vitamin D receptor
  • Transcription factor activated by vitamin D

    ATOH1 HAND 1 2 MESP2 Myogenic regulatory factors MyoD Myogenin MYF5 MYF6 NeuroD 1 2 Neurogenins 1 2 3 OLIG 1 2 Paraxis TCF15 Scleraxis SLC LYL1 TAL 1 2

    Vitamin D receptor

    Vitamin D receptor

    Vitamin_D_receptor

  • SOX9
  • Transcription factor gene of the SOX family

    ATOH1 HAND 1 2 MESP2 Myogenic regulatory factors MyoD Myogenin MYF5 MYF6 NeuroD 1 2 Neurogenins 1 2 3 OLIG 1 2 Paraxis TCF15 Scleraxis SLC LYL1 TAL 1 2

    SOX9

    SOX9

    SOX9

  • TANGO2
  • Protein-coding gene in the species Homo sapiens

    nucleophosphoproteins (with a RING finger binding motif) 222 232 - NEUR NeuroD, Beta2, HLH domain 214 226 - PCBE PREB core-binding element 148 162 - NR2F

    TANGO2

    TANGO2

    TANGO2

  • SMAD (protein)
  • Family of proteins

    ATOH1 HAND 1 2 MESP2 Myogenic regulatory factors MyoD Myogenin MYF5 MYF6 NeuroD 1 2 Neurogenins 1 2 3 OLIG 1 2 Paraxis TCF15 Scleraxis SLC LYL1 TAL 1 2

    SMAD (protein)

    SMAD_(protein)

  • AP-1 transcription factor
  • Instance of defined set in Homo sapiens with Reactome ID (R-HSA-6806560)

    ATOH1 HAND 1 2 MESP2 Myogenic regulatory factors MyoD Myogenin MYF5 MYF6 NeuroD 1 2 Neurogenins 1 2 3 OLIG 1 2 Paraxis TCF15 Scleraxis SLC LYL1 TAL 1 2

    AP-1 transcription factor

    AP-1 transcription factor

    AP-1_transcription_factor

  • Oct-4
  • Mammalian protein found in Homo sapiens

    ATOH1 HAND 1 2 MESP2 Myogenic regulatory factors MyoD Myogenin MYF5 MYF6 NeuroD 1 2 Neurogenins 1 2 3 OLIG 1 2 Paraxis TCF15 Scleraxis SLC LYL1 TAL 1 2

    Oct-4

    Oct-4

    Oct-4

  • CTCF
  • Transcription factor

    ATOH1 HAND 1 2 MESP2 Myogenic regulatory factors MyoD Myogenin MYF5 MYF6 NeuroD 1 2 Neurogenins 1 2 3 OLIG 1 2 Paraxis TCF15 Scleraxis SLC LYL1 TAL 1 2

    CTCF

    CTCF

    CTCF

  • HES4
  • ATOH1 HAND 1 2 MESP2 Myogenic regulatory factors MyoD Myogenin MYF5 MYF6 NeuroD 1 2 Neurogenins 1 2 3 OLIG 1 2 Paraxis TCF15 Scleraxis SLC LYL1 TAL 1 2

    HES4

    HES4

    HES4

  • KMT2A
  • Protein-coding gene in the species Homo sapiens

    ATOH1 HAND 1 2 MESP2 Myogenic regulatory factors MyoD Myogenin MYF5 MYF6 NeuroD 1 2 Neurogenins 1 2 3 OLIG 1 2 Paraxis TCF15 Scleraxis SLC LYL1 TAL 1 2

    KMT2A

    KMT2A

    KMT2A

  • Winged-helix transcription factors
  • Family of proteins

    ATOH1 HAND 1 2 MESP2 Myogenic regulatory factors MyoD Myogenin MYF5 MYF6 NeuroD 1 2 Neurogenins 1 2 3 OLIG 1 2 Paraxis TCF15 Scleraxis SLC LYL1 TAL 1 2

    Winged-helix transcription factors

    Winged-helix_transcription_factors

  • CLOCK
  • Human protein and coding gene

    ATOH1 HAND 1 2 MESP2 Myogenic regulatory factors MyoD Myogenin MYF5 MYF6 NeuroD 1 2 Neurogenins 1 2 3 OLIG 1 2 Paraxis TCF15 Scleraxis SLC LYL1 TAL 1 2

    CLOCK

    CLOCK

    CLOCK

  • Histone acetyltransferase
  • Enzymes that catalyze acyl group transfer from acetyl-CoA to histones

    include CIITA, Brm (chromatin remodeler), NF-κB (p65), TAL1/SCL, Beta2/NeuroD, C/EBPβ, IRF2, IRF7, YY1, KLF13, EVI1, AME, ER81, and the androgen receptor

    Histone acetyltransferase

    Histone acetyltransferase

    Histone_acetyltransferase

  • ASCL1
  • Protein-coding gene in humans

    ATOH1 HAND 1 2 MESP2 Myogenic regulatory factors MyoD Myogenin MYF5 MYF6 NeuroD 1 2 Neurogenins 1 2 3 OLIG 1 2 Paraxis TCF15 Scleraxis SLC LYL1 TAL 1 2

    ASCL1

    ASCL1

    ASCL1

  • AEBP2
  • Protein-coding gene in humans

    ATOH1 HAND 1 2 MESP2 Myogenic regulatory factors MyoD Myogenin MYF5 MYF6 NeuroD 1 2 Neurogenins 1 2 3 OLIG 1 2 Paraxis TCF15 Scleraxis SLC LYL1 TAL 1 2

    AEBP2

    AEBP2

    AEBP2

  • Subgranular zone
  • characteristics and begin expressing markers specific to granule cells such as NeuroD and Prox1. It is thought that the formation of these cells represents a

    Subgranular zone

    Subgranular zone

    Subgranular_zone

  • PRDM16
  • Protein-coding gene in the species Homo sapiens

    ATOH1 HAND 1 2 MESP2 Myogenic regulatory factors MyoD Myogenin MYF5 MYF6 NeuroD 1 2 Neurogenins 1 2 3 OLIG 1 2 Paraxis TCF15 Scleraxis SLC LYL1 TAL 1 2

    PRDM16

    PRDM16

    PRDM16

  • REPIN1
  • Protein-coding gene in the species Homo sapiens

    ATOH1 HAND 1 2 MESP2 Myogenic regulatory factors MyoD Myogenin MYF5 MYF6 NeuroD 1 2 Neurogenins 1 2 3 OLIG 1 2 Paraxis TCF15 Scleraxis SLC LYL1 TAL 1 2

    REPIN1

    REPIN1

    REPIN1

  • E2F
  • Family of transcription factors

    ATOH1 HAND 1 2 MESP2 Myogenic regulatory factors MyoD Myogenin MYF5 MYF6 NeuroD 1 2 Neurogenins 1 2 3 OLIG 1 2 Paraxis TCF15 Scleraxis SLC LYL1 TAL 1 2

    E2F

    E2F

  • PROX1
  • Protein-coding gene in the species Homo sapiens

    ATOH1 HAND 1 2 MESP2 Myogenic regulatory factors MyoD Myogenin MYF5 MYF6 NeuroD 1 2 Neurogenins 1 2 3 OLIG 1 2 Paraxis TCF15 Scleraxis SLC LYL1 TAL 1 2

    PROX1

    PROX1

    PROX1

  • BAZ1B
  • Protein-coding gene in the species Homo sapiens

    ATOH1 HAND 1 2 MESP2 Myogenic regulatory factors MyoD Myogenin MYF5 MYF6 NeuroD 1 2 Neurogenins 1 2 3 OLIG 1 2 Paraxis TCF15 Scleraxis SLC LYL1 TAL 1 2

    BAZ1B

    BAZ1B

    BAZ1B

  • Intracellular receptor
  • Receptors located inside the cell

    ATOH1 HAND 1 2 MESP2 Myogenic regulatory factors MyoD Myogenin MYF5 MYF6 NeuroD 1 2 Neurogenins 1 2 3 OLIG 1 2 Paraxis TCF15 Scleraxis SLC LYL1 TAL 1 2

    Intracellular receptor

    Intracellular_receptor

  • PEG3
  • Protein-coding gene in the species Homo sapiens

    ATOH1 HAND 1 2 MESP2 Myogenic regulatory factors MyoD Myogenin MYF5 MYF6 NeuroD 1 2 Neurogenins 1 2 3 OLIG 1 2 Paraxis TCF15 Scleraxis SLC LYL1 TAL 1 2

    PEG3

    PEG3

    PEG3

  • Zinc finger
  • Small structural protein motif found mostly in transcriptional proteins

    ATOH1 HAND 1 2 MESP2 Myogenic regulatory factors MyoD Myogenin MYF5 MYF6 NeuroD 1 2 Neurogenins 1 2 3 OLIG 1 2 Paraxis TCF15 Scleraxis SLC LYL1 TAL 1 2

    Zinc finger

    Zinc finger

    Zinc_finger

  • SOX17
  • Protein-coding gene in the species Homo sapiens

    ATOH1 HAND 1 2 MESP2 Myogenic regulatory factors MyoD Myogenin MYF5 MYF6 NeuroD 1 2 Neurogenins 1 2 3 OLIG 1 2 Paraxis TCF15 Scleraxis SLC LYL1 TAL 1 2

    SOX17

    SOX17

    SOX17

  • HMGB1
  • Mammalian protein found in Homo sapiens

    ATOH1 HAND 1 2 MESP2 Myogenic regulatory factors MyoD Myogenin MYF5 MYF6 NeuroD 1 2 Neurogenins 1 2 3 OLIG 1 2 Paraxis TCF15 Scleraxis SLC LYL1 TAL 1 2

    HMGB1

    HMGB1

    HMGB1

  • ZNF3
  • Protein-coding gene in the species Homo sapiens

    ATOH1 HAND 1 2 MESP2 Myogenic regulatory factors MyoD Myogenin MYF5 MYF6 NeuroD 1 2 Neurogenins 1 2 3 OLIG 1 2 Paraxis TCF15 Scleraxis SLC LYL1 TAL 1 2

    ZNF3

    ZNF3

    ZNF3

  • B-cell CLL/lymphoma
  • Family of genes

    ATOH1 HAND 1 2 MESP2 Myogenic regulatory factors MyoD Myogenin MYF5 MYF6 NeuroD 1 2 Neurogenins 1 2 3 OLIG 1 2 Paraxis TCF15 Scleraxis SLC LYL1 TAL 1 2

    B-cell CLL/lymphoma

    B-cell_CLL/lymphoma

  • SPI1
  • Protein-coding gene in the species Homo sapiens

    ATOH1 HAND 1 2 MESP2 Myogenic regulatory factors MyoD Myogenin MYF5 MYF6 NeuroD 1 2 Neurogenins 1 2 3 OLIG 1 2 Paraxis TCF15 Scleraxis SLC LYL1 TAL 1 2

    SPI1

    SPI1

    SPI1

  • Retinoid X receptor
  • Genes on human chromosome 9

    ATOH1 HAND 1 2 MESP2 Myogenic regulatory factors MyoD Myogenin MYF5 MYF6 NeuroD 1 2 Neurogenins 1 2 3 OLIG 1 2 Paraxis TCF15 Scleraxis SLC LYL1 TAL 1 2

    Retinoid X receptor

    Retinoid_X_receptor

  • Protein c-Fos
  • Mammalian protein found in Homo sapiens

    ATOH1 HAND 1 2 MESP2 Myogenic regulatory factors MyoD Myogenin MYF5 MYF6 NeuroD 1 2 Neurogenins 1 2 3 OLIG 1 2 Paraxis TCF15 Scleraxis SLC LYL1 TAL 1 2

    Protein c-Fos

    Protein c-Fos

    Protein_c-Fos

  • PRDM1
  • Protein-coding gene in the species Homo sapiens

    ATOH1 HAND 1 2 MESP2 Myogenic regulatory factors MyoD Myogenin MYF5 MYF6 NeuroD 1 2 Neurogenins 1 2 3 OLIG 1 2 Paraxis TCF15 Scleraxis SLC LYL1 TAL 1 2

    PRDM1

    PRDM1

    PRDM1

  • SPT20
  • Transcription factor

    ATOH1 HAND 1 2 MESP2 Myogenic regulatory factors MyoD Myogenin MYF5 MYF6 NeuroD 1 2 Neurogenins 1 2 3 OLIG 1 2 Paraxis TCF15 Scleraxis SLC LYL1 TAL 1 2

    SPT20

    SPT20

    SPT20

  • Mineralocorticoid receptor
  • Nuclear receptor that mediates the effects of the mineralocorticoid hormone Aldosterone

    ATOH1 HAND 1 2 MESP2 Myogenic regulatory factors MyoD Myogenin MYF5 MYF6 NeuroD 1 2 Neurogenins 1 2 3 OLIG 1 2 Paraxis TCF15 Scleraxis SLC LYL1 TAL 1 2

    Mineralocorticoid receptor

    Mineralocorticoid receptor

    Mineralocorticoid_receptor

  • TCF4
  • Protein-coding gene in the species Homo sapiens

    ATOH1 HAND 1 2 MESP2 Myogenic regulatory factors MyoD Myogenin MYF5 MYF6 NeuroD 1 2 Neurogenins 1 2 3 OLIG 1 2 Paraxis TCF15 Scleraxis SLC LYL1 TAL 1 2

    TCF4

    TCF4

    TCF4

  • Sterol regulatory element–binding protein 2
  • Protein-coding gene in the species Homo sapiens

    ATOH1 HAND 1 2 MESP2 Myogenic regulatory factors MyoD Myogenin MYF5 MYF6 NeuroD 1 2 Neurogenins 1 2 3 OLIG 1 2 Paraxis TCF15 Scleraxis SLC LYL1 TAL 1 2

    Sterol regulatory element–binding protein 2

    Sterol regulatory element–binding protein 2

    Sterol_regulatory_element–binding_protein_2

  • Retinoid receptor
  • Nuclear receptors that bind to retinoids

    ATOH1 HAND 1 2 MESP2 Myogenic regulatory factors MyoD Myogenin MYF5 MYF6 NeuroD 1 2 Neurogenins 1 2 3 OLIG 1 2 Paraxis TCF15 Scleraxis SLC LYL1 TAL 1 2

    Retinoid receptor

    Retinoid_receptor

  • Steroid hormone receptor
  • Group of protein families

    ATOH1 HAND 1 2 MESP2 Myogenic regulatory factors MyoD Myogenin MYF5 MYF6 NeuroD 1 2 Neurogenins 1 2 3 OLIG 1 2 Paraxis TCF15 Scleraxis SLC LYL1 TAL 1 2

    Steroid hormone receptor

    Steroid_hormone_receptor

  • Pregnane X receptor
  • Mammalian protein found in Homo sapiens

    ATOH1 HAND 1 2 MESP2 Myogenic regulatory factors MyoD Myogenin MYF5 MYF6 NeuroD 1 2 Neurogenins 1 2 3 OLIG 1 2 Paraxis TCF15 Scleraxis SLC LYL1 TAL 1 2

    Pregnane X receptor

    Pregnane X receptor

    Pregnane_X_receptor

  • Forkhead box B1
  • Protein-coding gene in the species Homo sapiens

    ATOH1 HAND 1 2 MESP2 Myogenic regulatory factors MyoD Myogenin MYF5 MYF6 NeuroD 1 2 Neurogenins 1 2 3 OLIG 1 2 Paraxis TCF15 Scleraxis SLC LYL1 TAL 1 2

    Forkhead box B1

    Forkhead box B1

    Forkhead_box_B1

  • Glucocorticoid receptor
  • Receptor to which cortisol and other glucocorticoids bind

    ATOH1 HAND 1 2 MESP2 Myogenic regulatory factors MyoD Myogenin MYF5 MYF6 NeuroD 1 2 Neurogenins 1 2 3 OLIG 1 2 Paraxis TCF15 Scleraxis SLC LYL1 TAL 1 2

    Glucocorticoid receptor

    Glucocorticoid receptor

    Glucocorticoid_receptor

  • EGR1
  • Protein-coding gene in the species Homo sapiens

    ATOH1 HAND 1 2 MESP2 Myogenic regulatory factors MyoD Myogenin MYF5 MYF6 NeuroD 1 2 Neurogenins 1 2 3 OLIG 1 2 Paraxis TCF15 Scleraxis SLC LYL1 TAL 1 2

    EGR1

    EGR1

    EGR1

  • INSM1
  • Protein-coding gene in the species Homo sapiens

    MS (July 2006). "INSM1 functions as a transcriptional repressor of the neuroD/beta2 gene through the recruitment of cyclin D1 and histone deacetylases"

    INSM1

    INSM1

    INSM1

  • NFX1
  • Protein-coding gene in the species Homo sapiens

    ATOH1 HAND 1 2 MESP2 Myogenic regulatory factors MyoD Myogenin MYF5 MYF6 NeuroD 1 2 Neurogenins 1 2 3 OLIG 1 2 Paraxis TCF15 Scleraxis SLC LYL1 TAL 1 2

    NFX1

    NFX1

    NFX1

  • Corticosteroid receptor
  • ATOH1 HAND 1 2 MESP2 Myogenic regulatory factors MyoD Myogenin MYF5 MYF6 NeuroD 1 2 Neurogenins 1 2 3 OLIG 1 2 Paraxis TCF15 Scleraxis SLC LYL1 TAL 1 2

    Corticosteroid receptor

    Corticosteroid receptor

    Corticosteroid_receptor

  • CCAAT-enhancer-binding proteins
  • Protein family

    ATOH1 HAND 1 2 MESP2 Myogenic regulatory factors MyoD Myogenin MYF5 MYF6 NeuroD 1 2 Neurogenins 1 2 3 OLIG 1 2 Paraxis TCF15 Scleraxis SLC LYL1 TAL 1 2

    CCAAT-enhancer-binding proteins

    CCAAT-enhancer-binding proteins

    CCAAT-enhancer-binding_proteins

  • Basic helix-loop-helix leucine zipper transcription factors
  • Type of transcription factor

    ATOH1 HAND 1 2 MESP2 Myogenic regulatory factors MyoD Myogenin MYF5 MYF6 NeuroD 1 2 Neurogenins 1 2 3 OLIG 1 2 Paraxis TCF15 Scleraxis SLC LYL1 TAL 1 2

    Basic helix-loop-helix leucine zipper transcription factors

    Basic_helix-loop-helix_leucine_zipper_transcription_factors

  • Small Maf
  • Class of proteins

    ATOH1 HAND 1 2 MESP2 Myogenic regulatory factors MyoD Myogenin MYF5 MYF6 NeuroD 1 2 Neurogenins 1 2 3 OLIG 1 2 Paraxis TCF15 Scleraxis SLC LYL1 TAL 1 2

    Small Maf

    Small_Maf

  • Octamer transcription factor
  • Group of proteins

    ATOH1 HAND 1 2 MESP2 Myogenic regulatory factors MyoD Myogenin MYF5 MYF6 NeuroD 1 2 Neurogenins 1 2 3 OLIG 1 2 Paraxis TCF15 Scleraxis SLC LYL1 TAL 1 2

    Octamer transcription factor

    Octamer_transcription_factor

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Online names & meanings

  • TOBIH
  • Male

    Hebrew

    TOBIH

    (טוֹבִת) Hebrew name TOBIH means "good" or "my God." In the Apocrypha, this is the name of the hero of the Book of Tobit.

  • Grubbs
  • Surname or Lastname

    English

    Grubbs

    English : variant of or patronymic form of Grubb.

  • Japhet
  • Girl/Female

    Biblical

    Japhet

    Enlarged, fair, persuading.

  • Ledari
  • Girl/Female

    Hindu, Indian

    Ledari

    Sweet

  • Thanusha
  • Girl/Female

    Hindu

    Thanusha

  • Maagadhee
  • Girl/Female

    Hindu, Indian

    Maagadhee

    Name of Daughter of Magadh King

  • Caston
  • Surname or Lastname

    English

    Caston

    English : habitational name from a place in Norfolk named Caston, from an unattested Old English personal name Catt or the Old Norse personal name Káti + Old English tūn ‘farmstead’, ‘settlement’.

  • EDUARD
  • Male

    German

    EDUARD

    German form of Latin Eduardus, EDUARD means "guardian of prosperity."

  • Asolf
  • Boy/Male

    Norse

    Asolf

    A kinsman of Jorund.

  • Halesya
  • Girl/Female

    Indian

    Halesya

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