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Processing of input impulses in a generic neuron
A binding neuron (BN) is an abstract concept of processing of input impulses in a generic neuron based on their temporal coherence and the level of neuronal
Binding_neuron
Mathematical function conceived as a crude model
An artificial neuron is a mathematical function conceived as a model of a biological neuron in a neural network. The artificial neuron is the elementary
Artificial_neuron
Mathematical descriptions of the properties of certain cells in the nervous system
Biological neuron models, also known as spiking neuron models, are mathematical descriptions of the conduction of electrical signals in neurons. Neurons (or
Biological_neuron_model
Neurological ramifications of and for the Binding Problem in the study of consciousness
pairing of neuron assemblies. The Temporal Binding Hypothesis was first proposed as a way of addressing the combinatorial problem of neural binding, which
Neural_binding
Primary cell of the nervous system
A neuron (American English), neurone (British English), or nerve cell, is a cell that is excitable, firing electric signals called action potentials across
Neuron
Topics referred to by the same term
pattern Binding neuron Binding problem, a term for several problems in cognitive science and philosophy Neural binding, synchronous activity of neurons and
Binding
Unanswered question in the study of consciousness
via synchronization of the activity of different neurons in the cortex. The theory, called binding-by-synchrony (BBS), is hypothesized to occur through
Binding_problem
Group of neurological disorders affecting motor neurons
Motor neuron diseases or motor neurone diseases (MNDs) are a group of rare neurodegenerative disorders that selectively affect motor neurons, the cells
Motor_neuron_diseases
Rare neurodegenerative disease
Amyotrophic lateral sclerosis (ALS), also known as motor neuron disease (MND) or Lou Gehrig's disease, is a rare terminal neurodegenerative disease defined
ALS
Protein in animal cells
Survival of motor neuron or survival motor neuron (SMN) is a protein that in humans is encoded by the SMN1 and SMN2 genes. SMN is found in the cytoplasm
Survival_of_motor_neuron
Soluble proteins secreted by auxiliary cells surrounding olfactory receptor neurons
Odorant-binding proteins (OBPs) are small (10 to 30 kDa) soluble proteins secreted by auxiliary cells surrounding olfactory receptor neurons, including
Odorant-binding_protein
Impulse transmission between neurons
terminal of a neuron (the presynaptic neuron), and bind to and react with the receptors on the dendrites of another neuron (the postsynaptic neuron) a short
Neurotransmission
Structure connecting neurons in the nervous system
In the nervous system, a synapse is a structure that allows a neuron to exchange (receive or send) signals with another cell in its immediate vicinity
Synapse
DNA-binding protein involved in methylation
However, the first large-scale mapping of MECP2 binding sites in neurons found that only 6% of the binding sites are in CpG islands, and that 63% of MECP2-bound
MECP2
Junction between motor neuron and muscle fiber
junction) is a chemical synapse between a motor neuron and a muscle fiber. It allows the motor neuron to transmit a signal to the muscle fiber, causing
Neuromuscular_junction
Nerve cell that converts environmental stimuli into corresponding internal stimuli
Sensory neurons, also known as afferent neurons, are in the nervous system which convert a specific type of stimulus, via their receptors, into action
Sensory_neuron
Sort of synapse
excitatory synapse is a synapse in which an action potential in a presynaptic neuron depolarizes the membrane of the postsynaptic cell, and thus increases the
Excitatory_synapse
Protein-coding gene in humans
conformations: implications for GABA(A) receptor localization and tubulin binding". Neuron. 33 (1): 63–74. doi:10.1016/S0896-6273(01)00558-X. PMID 11779480. S2CID 14487823
GABARAP
calcium-binding proteins contribute to all aspects of the cell's functioning, from homeostasis to learning and memory. For example, the neuron-specific
Calcium-binding_protein
Chemical substance that enables neurotransmission
Depending on the receptor, binding of neurotransmitters may cause excitation, inhibition, or modulation of the postsynaptic neuron. In order to avoid continuous
Neurotransmitter
Mammalian protein found in Homo sapiens
organizes the DNA and regulates transcription. After binding, HMGB1 bends DNA, which facilitates the binding of other proteins. HMGB1 supports transcription
HMGB1
Polymer of tubulin that forms part of the cytoskeleton
disease recapitulates development and contributes to reduced microtubule binding". Neuron. 10 (6): 1089–99. doi:10.1016/0896-6273(93)90057-X. PMID 8318230. S2CID 23180847
Microtubule
Mammalian protein found in humans
which stimulates the proliferation and survival of the target neuron. High affinity binding between proNGF, sortilin, and p75NTR can result in either survival
Nerve_growth_factor
Bacterial infection characterized by muscle spasms
presynaptic membrane of a motor neuron. The heavy chain C-terminal domain aids in binding to the correct site, recognizing and binding to the correct glycoproteins
Tetanus
Brainwaves, repetitive patterns of neural activity in the central nervous system
vertebrate neurons, but its functional role is still not fully understood. The possible roles of neural oscillations include feature binding, information
Neural_oscillation
Neurons in the hypothalamus central to hormonal control of reproduction
dynorphin (KNDy) neurons are neurons in the hypothalamus of the brain that are central to the hormonal control of reproduction. KNDy neurons in the hypothalamus
KNDy_neuron
Ionotropic receptor and ligand-gated ion channel
mechanism whereby GABA binding leads to ion channel opening. Because the reversal potential for chloride in most mature neurons is close to or more negative
GABAA_receptor
American biochemist and professor (1936–2024)
2025-05-29. Karlin, Arthur (March 25, 2004). "A touching picture of nicotinic binding". Neuron. 41: 841–2. doi:10.1016/s0896-6273(04)00151-5. PMID 15046715.
Arthur_Karlin
Protein-coding gene in the species Homo sapiens
(January 2010). "Experimental and computational studies indicate specific binding of pVHL protein to Aurora-A kinase". J Phys Chem B. 114 (3): 1486–1497
Aurora_kinase_A
Protein found in humans
characterized the transcriptome-wide binding sites revealing that thousands of RNAs are bound by TDP-43 in neurons. TDP-43 was originally identified as
TAR_DNA-binding_protein_43
Lower motor neuron involved in muscle contraction
A gamma motor neuron (γ motor neuron), also called gamma motoneuron, or fusimotor neuron, is a type of lower motor neuron that takes part in the process
Gamma_motor_neuron
Type of protein
number via control of postsynaptic β-actin mRNA metabolism. Neuron-specific CELF family RNA-binding protein UNC-75 specifically binds to the UUGUUGUGUUGU mRNA
RNA-binding_protein
Neuron communication by electric impulses
An action potential (also known as a nerve impulse or "spike" when in a neuron) is a series of quick changes in voltage across a cell membrane. An action
Action_potential
Family of proteins
function of neurons. They belong to a class of growth factors. Growth factors such as neurotrophins that promote the survival of neurons are known as
Neurotrophin
Antibody in molecular biology and neuroscience
is a neuronal nuclear antigen that is commonly used as a biomarker for neurons. NeuN was first described in 1992 by Mullen et al., who raised a series
NeuN
Protein-coding gene in the species Homo sapiens
RNA-binding protein Nova-1 is a protein that in humans is encoded by the NOVA1 gene. This gene encodes a neuron-specific RNA-binding protein, a member
NOVA1
Change in a cell's electric charge distribution
of an organism. It is especially important to electrical signaling in neurons and muscle cells. It also affects many non-excitable cells by changing
Depolarization
Metalloprotein that binds with oxygen
around 35% of the total weight (including water). Hemoglobin has an oxygen-binding capacity of 1.34 mL of O2 per gram, which increases the total blood oxygen
Hemoglobin
Type of brain cell
nervous system. Apolipoprotein E transports cholesterol from astrocytes to neurons and other glial cells, regulating cell signaling in the brain. Astrocytes
Astrocyte
Transmembrane protein family
AMPA-Sensitive Glutamate Receptor: Crystal Structures of the GluR2 Ligand Binding Core". Neuron. 28 (1): 165–181. doi:10.1016/S0896-6273(00)00094-5. PMID 11086992
AMPA_receptor
Biological process that adjusts the strength of connections between neurons in the brain
biological process that adjusts the strength of synaptic connections between neurons based on the relative timing of their action potentials (or spikes). It
Spike-timing-dependent plasticity
Spike-timing-dependent_plasticity
Sense that detects smells
dendrites of the olfactory sensory neurons. This may occur by diffusion or by the binding of the odorant to odorant-binding proteins. The mucus overlying the
Sense_of_smell
Protein found in humans
brain, it is primarily localized to the axon terminals of presynaptic neurons. There, it interacts with phospholipids and other proteins. Presynaptic
Alpha-synuclein
Class of proteins
CREB-TF (CREB, cAMP response element-binding protein) is a cellular transcription factor. It binds to certain DNA sequences called cAMP response elements
CREB
Critical protein in embryonic development
and in vivo result in floor plate induction and differentiation of motor neuron and ventral interneurons. On the other hand, mice mutants for SHH lack ventral
Sonic_hedgehog_protein
InterPro Family
has important roles in the survival and function of neurons in the central nervous system. The binding of BDNF to TrkB receptor causes many intracellular
Trk_receptor
Protein involved in multiple prion diseases
self-sustaining changes in learning-induced synaptic growth". Neuron. 44 (1): 49–57. doi:10.1016/j.neuron.2004.09.017. PMID 15450159. S2CID 2637074. Barco A, Bailey
Major_prion_protein
Cholesterol-transporting protein most notably implicated in Alzheimer's disease
Apo-E is mainly produced by astrocytes and transports cholesterol to neurons via Apo-E receptors, which are members of the low density lipoprotein receptor
Apolipoprotein_E
Protein family
domains bind different components to ensure correct arrangements. In the neuron, making sense of neurotransmitter activity requires specific receptors to
PDZ_domain
Sensory neuron that detects pain
A nociceptor (from Latin nocere 'to harm or hurt') is a sensory neuron that responds to damaging or potentially damaging stimuli by sending "possible threat"
Nociceptor
Mammalian protein found in humans
protein expressed in many tissues and concentrated in the synapses of neurons. It functions as a cell surface receptor and has been implicated as a regulator
Amyloid-beta precursor protein
Amyloid-beta_precursor_protein
Detectable change in the internal or external surroundings
normally glutamate binding to a neuron's dendrites, causing an influx of sodium ions through channels located near the binding site. This change in
Stimulus_(physiology)
Hypothetical neuron that responds to a single concept
grandmother cell, sometimes called the "Jennifer Aniston neuron", is a hypothetical neuron that represents a complex but specific concept or object.
Grandmother_cell
Group of six protein isoforms produced from the MAPT gene
maintaining the stability of microtubules in axons and are abundant in the neurons of the central nervous system (CNS), where the cerebral cortex has the
Tau_protein
Protein found in humans
transcription factor family. It represses transcription by binding a DNA sequence element called the neuron-restrictive silencer element (NRSE, also known as RE1)
RE1-silencing transcription factor
RE1-silencing_transcription_factor
Organic chemical and neurotransmitter
neuromuscular junction. In other words, it is the chemical that motor neurons of the nervous system release in order to activate muscles. This property
Acetylcholine
Protein-coding gene in the species Homo sapiens
impaired WASH complex binding through the VPS35-D620N mutation, GluR1 can be mistrafficked. Treating mouse hippocampal and cortical neurons with VPS35 small
VPS35
1998 theory of neuron classification
in 1998, states that neurons in the thalamus belong to either a parvalbumin-immunopositive core of precisely projecting neurons, or to a calbindin-immunopositive
Core-matrix theory of thalamus
Core-matrix_theory_of_thalamus
Small projection on a neuron that receives signals
or soma, of the neuron from which the dendrites project. Electrical stimulation is transmitted onto dendrites by upstream neurons (usually via their
Dendrite
Biochemical analysis procedure
on one neuron binds to the receptor on another, GFP expression is activated in the acceptor neuron demonstrating the usefulness of ligand binding assays
Ligand_binding_assay
Protein-coding gene in the species Homo sapiens
Non-POU domain-containing octamer-binding protein (NonO) is a protein that in humans is encoded by the NONO gene. The NonO protein belongs to the Drosophila
Non-POU domain-containing octamer-binding protein
Non-POU_domain-containing_octamer-binding_protein
American neuroscientist and biochemist
disease recapitulates development and contributes to reduced microtubule binding". Neuron. 10 (6): 1089–1099. doi:10.1016/0896-6273(93)90057-x. PMID 8318230
Virginia_Man-Yee_Lee
Toxin harmful to nervous tissue
is capable of long term binding to and inhibition of voltage-dependent calcium channels located in the membranes of neurons but not those of muscle cells
Neurotoxin
Protein-coding gene in the species Homo sapiens
disease characterized by a progressive loss of cerebellar neurons, particularly Purkinje neurons. ATXN1 is conserved across multiple species, including humans
Ataxin_1
Human protein and coding gene
FMRP has a diverse array of functions throughout different areas of the neuron; however these functions have not been fully characterized. FMRP has been
FMR1
Biological junctions through which neurons' signals can be sent
which neurons' signals can be sent to each other and to non-neuronal cells such as those in muscles or glands. Chemical synapses allow neurons to form
Chemical_synapse
Process of synapse elimination
growth of synaptic connections between neurons and the myelination of nerve fibers. The total number of neurons, however, remains approximately the same
Synaptic_pruning
Reabsorption of a neurotransmitter by a neurotransmitter transporter
into the presynaptic neuron, increasing the concentration of neurotransmitter in the synapse. This increases neurotransmitter binding to pre- and postsynaptic
Reuptake
Motor protein in humans
KIF1A, is a protein that in humans is encoded by the KIF1A gene. KIF1A is a neuron-specific member of the kinesin-3 family and is a microtubule plus end-directed
KIF1A
Protein-coding gene in the species Homo sapiens
Binding immunoglobulin protein (BiPS) also known as 78 kDa glucose-regulated protein (GRP-78) or heat shock 70 kDa protein 5 (HSPA5) is a protein that
Binding immunoglobulin protein
Binding_immunoglobulin_protein
HSD2 neurons are a small group of neurons in the brainstem which are uniquely sensitive to the mineralocorticosteroid hormone aldosterone, through expression
HSD2_neuron
Process of remodeling actin filaments in neurons
remodeling is a biochemical process in cells. In the actin remodeling of neurons, the protein actin is part of the process to change the shape and structure
Actin_remodeling_of_neurons
Mammalian protein
puberty. This research led to the discovery that kisspeptin stimulates the neurons that were involved in the release of gonadotropin-releasing hormone (GnRH)
Kisspeptin
Cell that guides radial neuronal migration
Jones EG (April 1990). "Cajal-Retzius neurons in developing monkey neocortex show immunoreactivity for calcium binding proteins". Journal of Neurocytology
Cajal–Retzius_cell
Type of GABAergic neuron in the striatum
Medium spiny neurons (MSNs), also known as spiny projection neurons (SPNs), are a special type of inhibitory GABAergic neuron representing approximately
Medium_spiny_neuron
Glutamate receptor and ion channel protein found in nerve cells
the binding of the ligands is typically not sufficient to open the channel as it may be blocked by Mg2+ ions which are only removed when the neuron is
NMDA_receptor
Protein family
Polypyrimidine tract-binding protein, also known as PTB or hnRNP I, is an RNA-binding protein. PTB functions mainly as a splicing regulator, although it
Polypyrimidine tract-binding protein
Polypyrimidine_tract-binding_protein
Central nervous system disease
A neurodegenerative disease is caused by the progressive loss of neurons, in the process known as neurodegeneration. Neuronal damage may also ultimately
Neurodegenerative_disease
Function of chemical receptors
proteins including OBPs (odorant-binding proteins), CSPs (chemosensory binding proteins), and SNMPs (sensory neuron membrane proteins) that help the moth
Insect_olfaction
Small protrusion on a dendrite that receives input from a single axon
A dendritic spine (or spine) is a small membrane protrusion from a neuron's dendrite that typically receives input from a single axon at the synapse. Dendritic
Dendritic_spine
Mammalian protein found in Homo sapiens
in the post synaptic density of neurons, and is involved in anchoring synaptic proteins. Its direct and indirect binding partners include neuroligin, NMDA
DLG4
Any process that modulates the potential difference across a post-synaptic membrane
inhibit action potentials. Postsynaptic potentials occur when the presynaptic neuron releases neurotransmitters into the synaptic cleft. These neurotransmitters
Postsynaptic_potential
Protein
CPEB, or cytoplasmic polyadenylation element binding protein, is a highly conserved RNA-binding protein that promotes the elongation of the polyadenine
CPEB
Family of transport proteins
Vesicle filling may limit monoamine release from neurons with high rates of firing. Specific amine-binding affinity varies by VMAT isoform; studies indicate
Vesicular monoamine transporter
Vesicular_monoamine_transporter
Type of ion channel transmembrane protein
membrane in response to the binding of a chemical messenger (i.e. a ligand), such as a neurotransmitter. When a presynaptic neuron is excited, it releases
Ligand-gated_ion_channel
Protein-coding gene in the species Homo sapiens
(September 1997). "Myelin-associated glycoprotein interacts with neurons via a sialic acid binding site at ARG118 and a distinct neurite inhibition site". The
Myelin-associated glycoprotein
Myelin-associated_glycoprotein
Acetylcholine receptors named for their selective binding of nicotine
signaling shapes nervous system function and behavior". Neuron. 76 (1): 116–29. doi:10.1016/j.neuron.2012.08.036. PMC 3466476. PMID 23040810. Wonnacott S
Nicotinic acetylcholine receptor
Nicotinic_acetylcholine_receptor
Protein-coding gene in humans
(ApoER2) and becomes tyrosine-phosphorylated following binding of Reelin to cortical neurons. In mice, mutations of Dab1 and Reelin generate identical
DAB1
Mammalian protein found in Homo sapiens
and characterization of the binding site for the regulatory subunit of type II cAMP-dependent protein kinase on MAP2". Neuron. 3 (5): 631–8. doi:10
Microtubule-associated protein 2
Microtubule-associated_protein_2
Protein and coding gene in humans
of synaptic structures during synaptic plasticity". Neuron. 82 (2): 430–443. doi:10.1016/j.neuron.2014.02.031. PMID 24742464. Albert PR (October 2019)
HOMER1
Protein-coding gene in the species Homo sapiens
conformations: implications for GABA(A) receptor localization and tubulin binding". Neuron. 33 (1): 63–74. doi:10.1016/S0896-6273(01)00558-X. PMID 11779480. S2CID 14487823
Gamma-aminobutyric acid receptor subunit gamma-2
Gamma-aminobutyric_acid_receptor_subunit_gamma-2
Repeating unit of a myofibril in a muscle cell
endoplasmic reticulum in the sarcoplasm. Muscle cells are stimulated when a motor neuron releases the neurotransmitter acetylcholine, which travels across the neuromuscular
Sarcomere
Protein found in humans
synapses of locally stimulated neurons. PSD-95 localizes the actin-remodeling GTPases, Rac and Rho, to synapses through the binding of its PDZ domain to kalirin
Brain-derived neurotrophic factor
Brain-derived_neurotrophic_factor
Protein-coding gene in the species Homo sapiens
whereas PC3 was originally isolated as sequence induced at the beginning of neuron differentiation; BTG2 was then isolated in human cells as sequence induced
Protein_BTG2
Protein and coding gene in humans
tyrosine kinase located at the cellular membrane, and is activated by the binding of a ligand to the receptor's extracellular domain. Other examples of tyrosine
Tropomyosin_receptor_kinase_B
Changes in membrane potential varying in size
channels. They occur at the postsynaptic dendrite in response to presynaptic neuron firing and release of neurotransmitter, or may occur in skeletal, smooth
Graded_potential
Interdisciplinary scientific study of cognitive processes
Press. Malsburg, C. von der (1999). "The what and why of binding: The modeler's perspective". Neuron. 24: 95-104. Gray, C. M. & Singer, W. (1989). "Stimulus-specific
Cognitive_science
Protein-coding gene in the species Homo sapiens
Syntaxin-binding protein 1 (also known as Munc18-1) is a protein that in humans is encoded by the STXBP1 gene. This gene encodes a syntaxin-binding protein
STXBP1
Protein found in humans
on certain neurons of the peripheral and central nervous system; it helps to support the survival and differentiation of existing neurons, and encourages
Neurotrophin-3
Mammalian protein found in humans
neurons by ubiquitinating other Lewy body constituents, such as the p38 subunit of aminoacyl-tRNA synthetase complex and far upstream element-binding
Parkin_(protein)
BINDING NEURON
BINDING NEURON
Biblical
fearful; binding
Girl/Female
Indian
A bond, One who glues together, Is bound, Preserve
Surname or Lastname
English
English : variant of Balding.
Biblical
hiding, binding
Surname or Lastname
English and German
English and German : patronymic from Bold as a personal name.Danish : habitational name from a place so named in Jutland.
Surname or Lastname
English
English : unexplained.German : patronymic from a personal name formed with Ban- ‘decree’, ‘command’ or Band- ‘band’, ‘tie’.
Girl/Female
Biblical
Fearful, binding.
Boy/Male
Arabic, Muslim, Sindhi
Binding; Fastening
Boy/Male
Muslim
Binding, Fastening
Surname or Lastname
English and Scottish
English and Scottish : of uncertain derivation; possibly related to Bing.
Surname or Lastname
English
English : nickname from some fancied resemblance to the songbird (Emberiza spp.).German : patronymic from an unexplained Frisian-Lower Saxon personal name, or a derivative of Bunt- (see Bunten).Sarah Bunting (1686–1762), born in Matlock, Derbyshire, became a noted Quaker minister in Cross Wicks, NJ. It is believed but not certain that other members of her family, including her father, John Bunting, came with her to NJ sometime before 1704, when her marriage to William Murfin is recorded.
Girl/Female
Indian
A dot on the forehead. the one which indian women who put down the same in between two eyebrows, Drop, Point
Surname or Lastname
English
English : unexplained.
Surname or Lastname
English (now chiefly Lancashire)
English (now chiefly Lancashire) : from an unattested Old English personal name, Wilding, a derivative of Old English wilde ‘wild’, ‘savage’. It is also possible that it may be from a topographical term derived from the same vocabulary word. Compare Wild, but early forms with prepositions are not found.German : patronymic from Wilto, a short form of a Germanic personal name beginning with wild ‘wild’.
Surname or Lastname
English
English : variant of Blanton.
Boy/Male
Muslim/Islamic
Binding Fastening
Surname or Lastname
English
English : either from a Middle English survival of an Old English personal name, Billing, or a habitational name from a place in Northamptonshire called Billing, probably ‘(settlement of) the followers (Old English -ingas) of a man called Bill(a)’.German : from a Germanic personal name, formed with a cognate of Old Saxon bīl ‘sword’.Danish and Norwegian : from an Old Danish personal name, Billing.Swedish : shortened form of various habitational names such as Billinge, Billingsfors, etc.
Girl/Female
Biblical
Hiding, binding.
Surname or Lastname
English (Hampshire and the Isle of Wight)
English (Hampshire and the Isle of Wight) : habitational name from a place on the Isle of Wight named Brading, from Old English brerd ‘hillside’ + -ingas ‘dwellers at’, i.e. ‘(settlement of) the dwellers on the hillside’.
Surname or Lastname
English (chiefly Yorkshire)
English (chiefly Yorkshire) : unexplained; perhaps a variant of Browning. Compare Brunning.Americanized spelling of German Breuning (see Breunig).
BINDING NEURON
BINDING NEURON
Male
African
father.
Girl/Female
Biblical
Beloved.
Boy/Male
Scandinavian Teutonic American German
Peaceful ruler.
Boy/Male
Hindi Muslim
Devoted; true.
Girl/Female
Hindu, Indian
Goddess; Respect Love
Male
Scottish
Scottish name derived from Crìosd, CRÌSDEAN means "Christ." Used as a form of English Christopher, meaning "Christ-bearer."
Girl/Female
Hebrew
Hope.
Boy/Male
English Teutonic
Son of All.
Surname or Lastname
English
English : habitational name from any of the places called Bradshaw, for example in Lancashire and West Yorkshire, from Old English brÄd ‘broad’ + sceaga ‘thicket’.
Girl/Female
Muslim/Islamic
Beautiful
BINDING NEURON
BINDING NEURON
BINDING NEURON
BINDING NEURON
BINDING NEURON
n.
The act of finding fault or blaming; -- used derogatively. Also Adj.
n.
The beads or bead-forming quality of certain liquors; as, the beading of a brand of whisky.
n.
A winding, bending, or twisting.
a.
That binds; obligatory.
p. pr. & vb. n.
of Bind
a.
Bending in and out; of a serpentine or undulating form; winding; crooked.
v. t.
A building.
n.
The result of a judicial examination or inquiry, especially into some matter of fact; a verdict; as, the finding of a jury.
a.
Abiding the law; waiting for the operation of law for the enforcement of rights; also, abiding by the law; obedient to the law; as, law-abiding people.
n.
A machine formerly used for bending a crossbow by winding it up.
a.
Making blind or as if blind; depriving of sight or of understanding; obscuring; as, blinding tears; blinding snow.
pl.
The transoms, knees, beams, keelson, and other chief timbers used for connecting and strengthening the parts of a vessel.
a.
Bulged; bulging; bending, or tending to bend, outward.
a.
Bringing dishonor on; tending to disgrace; lessening reputation.
n.
State of sinking or bending; sagging.
a.
Wound by mechanism connected with the stem; as, a stem-winding watch.
n.
A winding or bending in and out.
n.
Anything that binds; a bandage; the cover of a book, or the cover with the sewing, etc.; something that secures the edge of cloth from raveling.
n.
The act or process of one who, or that which, binds.