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PDK2

  • PDK2
  • Protein-coding gene in the species Homo sapiens

    (PDK2) also known as pyruvate dehydrogenase lipoamide kinase isozyme 2, mitochondrial is an enzyme that in humans is encoded by the PDK2 gene. PDK2 is

    PDK2

    PDK2

    PDK2

  • Pyruvate dehydrogenase kinase
  • Class of enzymes

    At site 1 in order from fastest to slowest, PDK2 > PDK4 ≈ PDK1 > PDK3. For site 2, PDK3 > PDK4 > PDK2 > PDK1. Only PDK1 can phosphorylate site 3. However

    Pyruvate dehydrogenase kinase

    Pyruvate dehydrogenase kinase

    Pyruvate_dehydrogenase_kinase

  • PHLPP
  • Class of enzymes

    activity. The PHLPPs therefore antagonize PDK1 and PDK2, since they dephosphorylate the site that PDK2 phosphorylates. PHLPP1 and 2 also dephosphorylate

    PHLPP

    PHLPP

  • Protein kinase B
  • Set of three serine threonine-specific protein kinases

    first by mTORC2. mTORC2 therefore functionally acts as the long-sought PDK2 molecule, although other molecules, including integrin-linked kinase (ILK)

    Protein kinase B

    Protein kinase B

    Protein_kinase_B

  • Metal transporter CNNM3
  • Protein, forming human gene

    been prove that CNNM3 is one of the most correlated genes to PDK2 in lung adenocarcinoma. PDK2 regulates the activity of the CNNM3 promoter in lung adenocarcinoma

    Metal transporter CNNM3

    Metal_transporter_CNNM3

  • PDK4
  • Protein-coding gene in the species Homo sapiens

    dehydrogenase kinase that have been shown to phosphorylate these three sites: PDK1, PDK2, PDK3, and PDK4. PDK4 does not incorporate the most phosphate groups per

    PDK4

    PDK4

    PDK4

  • GHKL domain
  • Evolutionary conserved protein domain

    HSP90AA1, HSP90AB1, HSP90B1 MLH1, MLH3, MORC1, MORC2, MORC3, MORC4 PDK1, PDK2, PDK3, PDK4 PMS1, PMS2, PMS2L1, PMS2L11, PMS2L3, PMS4L TOP2A, TOP2B TRAP1

    GHKL domain

    GHKL domain

    GHKL_domain

  • PDK3
  • Protein-coding gene in the species Homo sapiens

    Dehydrogenase Kinase that have been shown to phosphorylate these three sites: PDK1, PDK2, PDK3, and PDK4. The PDK3 protein is primarily found in the kidney, brain

    PDK3

    PDK3

    PDK3

  • BRAF (gene)
  • Protein-coding gene in humans

    EIF2AK3 EIF2AK4 Wee1 WEE1 Pyruvate dehydrogenase kinase (EC 2.7.11.2) PDK1 PDK2 PDK3 PDK4 Dephospho-(reductase kinase) kinase (EC 2.7.11.3) AMP-activated

    BRAF (gene)

    BRAF (gene)

    BRAF_(gene)

  • Titin
  • Largest known protein in human muscles

    EIF2AK3 EIF2AK4 Wee1 WEE1 Pyruvate dehydrogenase kinase (EC 2.7.11.2) PDK1 PDK2 PDK3 PDK4 Dephospho-(reductase kinase) kinase (EC 2.7.11.3) AMP-activated

    Titin

    Titin

    Titin

  • AKT1
  • Protein-coding gene in humans

    EIF2AK3 EIF2AK4 Wee1 WEE1 Pyruvate dehydrogenase kinase (EC 2.7.11.2) PDK1 PDK2 PDK3 PDK4 Dephospho-(reductase kinase) kinase (EC 2.7.11.3) AMP-activated

    AKT1

    AKT1

    AKT1

  • PRKCI
  • Protein-coding gene in the species Homo sapiens

    EIF2AK3 EIF2AK4 Wee1 WEE1 Pyruvate dehydrogenase kinase (EC 2.7.11.2) PDK1 PDK2 PDK3 PDK4 Dephospho-(reductase kinase) kinase (EC 2.7.11.3) AMP-activated

    PRKCI

    PRKCI

    PRKCI

  • Rho-associated protein kinase
  • Protein family

    EIF2AK3 EIF2AK4 Wee1 WEE1 Pyruvate dehydrogenase kinase (EC 2.7.11.2) PDK1 PDK2 PDK3 PDK4 Dephospho-(reductase kinase) kinase (EC 2.7.11.3) AMP-activated

    Rho-associated protein kinase

    Rho-associated protein kinase

    Rho-associated_protein_kinase

  • Myosin-heavy-chain kinase
  • Class of enzymes

    EIF2AK3 EIF2AK4 Wee1 WEE1 Pyruvate dehydrogenase kinase (EC 2.7.11.2) PDK1 PDK2 PDK3 PDK4 Dephospho-(reductase kinase) kinase (EC 2.7.11.3) AMP-activated

    Myosin-heavy-chain kinase

    Myosin-heavy-chain_kinase

  • Ribosomal s6 kinase
  • Family of protein kinases

    EIF2AK3 EIF2AK4 Wee1 WEE1 Pyruvate dehydrogenase kinase (EC 2.7.11.2) PDK1 PDK2 PDK3 PDK4 Dephospho-(reductase kinase) kinase (EC 2.7.11.3) AMP-activated

    Ribosomal s6 kinase

    Ribosomal s6 kinase

    Ribosomal_s6_kinase

  • Aurora kinase B
  • Protein

    EIF2AK3 EIF2AK4 Wee1 WEE1 Pyruvate dehydrogenase kinase (EC 2.7.11.2) PDK1 PDK2 PDK3 PDK4 Dephospho-(reductase kinase) kinase (EC 2.7.11.3) AMP-activated

    Aurora kinase B

    Aurora kinase B

    Aurora_kinase_B

  • C-Jun N-terminal kinases
  • Chemical compounds

    EIF2AK3 EIF2AK4 Wee1 WEE1 Pyruvate dehydrogenase kinase (EC 2.7.11.2) PDK1 PDK2 PDK3 PDK4 Dephospho-(reductase kinase) kinase (EC 2.7.11.3) AMP-activated

    C-Jun N-terminal kinases

    C-Jun N-terminal kinases

    C-Jun_N-terminal_kinases

  • STK19
  • Protein-coding gene in humans

    EIF2AK3 EIF2AK4 Wee1 WEE1 Pyruvate dehydrogenase kinase (EC 2.7.11.2) PDK1 PDK2 PDK3 PDK4 Dephospho-(reductase kinase) kinase (EC 2.7.11.3) AMP-activated

    STK19

    STK19

    STK19

  • Mitogen-activated protein kinase
  • P38 mitogen-activated protein kinases

    EIF2AK3 EIF2AK4 Wee1 WEE1 Pyruvate dehydrogenase kinase (EC 2.7.11.2) PDK1 PDK2 PDK3 PDK4 Dephospho-(reductase kinase) kinase (EC 2.7.11.3) AMP-activated

    Mitogen-activated protein kinase

    Mitogen-activated_protein_kinase

  • PKMYT1
  • Protein-coding gene in the species Homo sapiens

    EIF2AK3 EIF2AK4 Wee1 WEE1 Pyruvate dehydrogenase kinase (EC 2.7.11.2) PDK1 PDK2 PDK3 PDK4 Dephospho-(reductase kinase) kinase (EC 2.7.11.3) AMP-activated

    PKMYT1

    PKMYT1

    PKMYT1

  • Akt/PKB signaling pathway
  • Series of biochemical reactions

    catalysed by multiple proteins, including phosphoinositide-dependent kinase 2 (PDK2), integrin-linked kinase (ILK), mechanistic target of rapamycin complex complex

    Akt/PKB signaling pathway

    Akt/PKB_signaling_pathway

  • SMG1
  • Protein-coding gene in the species Homo sapiens

    EIF2AK3 EIF2AK4 Wee1 WEE1 Pyruvate dehydrogenase kinase (EC 2.7.11.2) PDK1 PDK2 PDK3 PDK4 Dephospho-(reductase kinase) kinase (EC 2.7.11.3) AMP-activated

    SMG1

    SMG1

    SMG1

  • Protein kinase C zeta type
  • Mammalian protein found in Homo sapiens

    PMID 25058929. Hodgkinson CP, Sale EM, Sale GJ (2002). "Characterization of PDK2 activity against protein kinase B gamma". Biochemistry. 41 (32): 10351–9

    Protein kinase C zeta type

    Protein kinase C zeta type

    Protein_kinase_C_zeta_type

  • STK4
  • Protein-coding gene in the species Homo sapiens

    EIF2AK3 EIF2AK4 Wee1 WEE1 Pyruvate dehydrogenase kinase (EC 2.7.11.2) PDK1 PDK2 PDK3 PDK4 Dephospho-(reductase kinase) kinase (EC 2.7.11.3) AMP-activated

    STK4

    STK4

    STK4

  • TSSK2
  • Protein-coding gene in the species Homo sapiens

    EIF2AK3 EIF2AK4 Wee1 WEE1 Pyruvate dehydrogenase kinase (EC 2.7.11.2) PDK1 PDK2 PDK3 PDK4 Dephospho-(reductase kinase) kinase (EC 2.7.11.3) AMP-activated

    TSSK2

    TSSK2

    TSSK2

  • Cyclin-dependent kinase 10
  • Protein-coding gene in the species Homo sapiens

    EIF2AK3 EIF2AK4 Wee1 WEE1 Pyruvate dehydrogenase kinase (EC 2.7.11.2) PDK1 PDK2 PDK3 PDK4 Dephospho-(reductase kinase) kinase (EC 2.7.11.3) AMP-activated

    Cyclin-dependent kinase 10

    Cyclin-dependent kinase 10

    Cyclin-dependent_kinase_10

  • PLK2
  • Protein-coding gene in the species Homo sapiens

    EIF2AK3 EIF2AK4 Wee1 WEE1 Pyruvate dehydrogenase kinase (EC 2.7.11.2) PDK1 PDK2 PDK3 PDK4 Dephospho-(reductase kinase) kinase (EC 2.7.11.3) AMP-activated

    PLK2

    PLK2

    PLK2

  • Serine/threonine-specific protein kinase
  • Class of protein kinase enzymes

    EIF2AK3 EIF2AK4 Wee1 WEE1 Pyruvate dehydrogenase kinase (EC 2.7.11.2) PDK1 PDK2 PDK3 PDK4 Dephospho-(reductase kinase) kinase (EC 2.7.11.3) AMP-activated

    Serine/threonine-specific protein kinase

    Serine/threonine-specific protein kinase

    Serine/threonine-specific_protein_kinase

  • SNF1LK2
  • Protein-coding gene in the species Homo sapiens

    EIF2AK3 EIF2AK4 Wee1 WEE1 Pyruvate dehydrogenase kinase (EC 2.7.11.2) PDK1 PDK2 PDK3 PDK4 Dephospho-(reductase kinase) kinase (EC 2.7.11.3) AMP-activated

    SNF1LK2

    SNF1LK2

    SNF1LK2

  • STK38L
  • Protein-coding gene in the species Homo sapiens

    EIF2AK3 EIF2AK4 Wee1 WEE1 Pyruvate dehydrogenase kinase (EC 2.7.11.2) PDK1 PDK2 PDK3 PDK4 Dephospho-(reductase kinase) kinase (EC 2.7.11.3) AMP-activated

    STK38L

    STK38L

    STK38L

  • Cyclin-dependent kinase
  • Class of enzymes

    EIF2AK3 EIF2AK4 Wee1 WEE1 Pyruvate dehydrogenase kinase (EC 2.7.11.2) PDK1 PDK2 PDK3 PDK4 Dephospho-(reductase kinase) kinase (EC 2.7.11.3) AMP-activated

    Cyclin-dependent kinase

    Cyclin-dependent kinase

    Cyclin-dependent_kinase

  • Protein kinase R
  • Human protein and coding gene

    EIF2AK3 EIF2AK4 Wee1 WEE1 Pyruvate dehydrogenase kinase (EC 2.7.11.2) PDK1 PDK2 PDK3 PDK4 Dephospho-(reductase kinase) kinase (EC 2.7.11.3) AMP-activated

    Protein kinase R

    Protein kinase R

    Protein_kinase_R

  • Aurora kinase A
  • Protein-coding gene in the species Homo sapiens

    EIF2AK3 EIF2AK4 Wee1 WEE1 Pyruvate dehydrogenase kinase (EC 2.7.11.2) PDK1 PDK2 PDK3 PDK4 Dephospho-(reductase kinase) kinase (EC 2.7.11.3) AMP-activated

    Aurora kinase A

    Aurora kinase A

    Aurora_kinase_A

  • STK38
  • Protein-coding gene in the species Homo sapiens

    EIF2AK3 EIF2AK4 Wee1 WEE1 Pyruvate dehydrogenase kinase (EC 2.7.11.2) PDK1 PDK2 PDK3 PDK4 Dephospho-(reductase kinase) kinase (EC 2.7.11.3) AMP-activated

    STK38

    STK38

    STK38

  • Protein kinase C
  • Family of enzymes

    EIF2AK3 EIF2AK4 Wee1 WEE1 Pyruvate dehydrogenase kinase (EC 2.7.11.2) PDK1 PDK2 PDK3 PDK4 Dephospho-(reductase kinase) kinase (EC 2.7.11.3) AMP-activated

    Protein kinase C

    Protein_kinase_C

  • Phosphatidylinositol 3-kinase-related kinase
  • Protein family

    EIF2AK3 EIF2AK4 Wee1 WEE1 Pyruvate dehydrogenase kinase (EC 2.7.11.2) PDK1 PDK2 PDK3 PDK4 Dephospho-(reductase kinase) kinase (EC 2.7.11.3) AMP-activated

    Phosphatidylinositol 3-kinase-related kinase

    Phosphatidylinositol_3-kinase-related_kinase

  • MAP kinase kinase kinase
  • Class of enzymes

    EIF2AK3 EIF2AK4 Wee1 WEE1 Pyruvate dehydrogenase kinase (EC 2.7.11.2) PDK1 PDK2 PDK3 PDK4 Dephospho-(reductase kinase) kinase (EC 2.7.11.3) AMP-activated

    MAP kinase kinase kinase

    MAP_kinase_kinase_kinase

  • (acetyl-CoA carboxylase) kinase
  • Class of enzymes

    EIF2AK3 EIF2AK4 Wee1 WEE1 Pyruvate dehydrogenase kinase (EC 2.7.11.2) PDK1 PDK2 PDK3 PDK4 Dephospho-(reductase kinase) kinase (EC 2.7.11.3) AMP-activated

    (acetyl-CoA carboxylase) kinase

    (acetyl-CoA_carboxylase)_kinase

  • AMP-activated protein kinase
  • Class of enzymes

    EIF2AK3 EIF2AK4 Wee1 WEE1 Pyruvate dehydrogenase kinase (EC 2.7.11.2) PDK1 PDK2 PDK3 PDK4 Dephospho-(reductase kinase) kinase (EC 2.7.11.3) AMP-activated

    AMP-activated protein kinase

    AMP-activated protein kinase

    AMP-activated_protein_kinase

  • Extracellular signal-regulated kinases
  • Class of enzymes

    EIF2AK3 EIF2AK4 Wee1 WEE1 Pyruvate dehydrogenase kinase (EC 2.7.11.2) PDK1 PDK2 PDK3 PDK4 Dephospho-(reductase kinase) kinase (EC 2.7.11.3) AMP-activated

    Extracellular signal-regulated kinases

    Extracellular_signal-regulated_kinases

  • AKT3
  • Protein-coding gene in humans

    B, gamma)". Hodgkinson CP, Sale EM, Sale GJ (2002). "Characterization of PDK2 activity against protein kinase B gamma". Biochemistry. 41 (32): 10351–9

    AKT3

    AKT3

    AKT3

  • Aurora inhibitor
  • Putative drug class for treating cancer

    EIF2AK3 EIF2AK4 Wee1 WEE1 Pyruvate dehydrogenase kinase (EC 2.7.11.2) PDK1 PDK2 PDK3 PDK4 Dephospho-(reductase kinase) kinase (EC 2.7.11.3) AMP-activated

    Aurora inhibitor

    Aurora inhibitor

    Aurora_inhibitor

  • MASTL
  • Protein-coding gene in the species Homo sapiens

    EIF2AK3 EIF2AK4 Wee1 WEE1 Pyruvate dehydrogenase kinase (EC 2.7.11.2) PDK1 PDK2 PDK3 PDK4 Dephospho-(reductase kinase) kinase (EC 2.7.11.3) AMP-activated

    MASTL

    MASTL

    MASTL

  • Phosphoinositide-dependent kinase-1
  • Protein-coding gene in the species Homo sapiens

    is mediated by 3-phosphoinositide-dependent protein kinase-1 (PDK1) and PDK2". The Biochemical Journal. 339 ( Pt 2) (2): 319–328. doi:10.1042/0264-6021:3390319

    Phosphoinositide-dependent kinase-1

    Phosphoinositide-dependent kinase-1

    Phosphoinositide-dependent_kinase-1

  • MTORC1
  • Protein complex

    EIF2AK3 EIF2AK4 Wee1 WEE1 Pyruvate dehydrogenase kinase (EC 2.7.11.2) PDK1 PDK2 PDK3 PDK4 Dephospho-(reductase kinase) kinase (EC 2.7.11.3) AMP-activated

    MTORC1

    MTORC1

    MTORC1

  • DNA-PKcs
  • Protein found in humans

    EIF2AK3 EIF2AK4 Wee1 WEE1 Pyruvate dehydrogenase kinase (EC 2.7.11.2) PDK1 PDK2 PDK3 PDK4 Dephospho-(reductase kinase) kinase (EC 2.7.11.3) AMP-activated

    DNA-PKcs

    DNA-PKcs

    DNA-PKcs

  • MTOR
  • Mammalian protein found in humans

    EIF2AK3 EIF2AK4 Wee1 WEE1 Pyruvate dehydrogenase kinase (EC 2.7.11.2) PDK1 PDK2 PDK3 PDK4 Dephospho-(reductase kinase) kinase (EC 2.7.11.3) AMP-activated

    MTOR

    MTOR

    MTOR

  • MAP kinase kinase kinase kinase
  • Family of proteins

    EIF2AK3 EIF2AK4 Wee1 WEE1 Pyruvate dehydrogenase kinase (EC 2.7.11.2) PDK1 PDK2 PDK3 PDK4 Dephospho-(reductase kinase) kinase (EC 2.7.11.3) AMP-activated

    MAP kinase kinase kinase kinase

    MAP_kinase_kinase_kinase_kinase

  • IkappaB kinase
  • Class of enzymes

    EIF2AK3 EIF2AK4 Wee1 WEE1 Pyruvate dehydrogenase kinase (EC 2.7.11.2) PDK1 PDK2 PDK3 PDK4 Dephospho-(reductase kinase) kinase (EC 2.7.11.3) AMP-activated

    IkappaB kinase

    IkappaB_kinase

  • GSK3A
  • Protein-coding gene in the species Homo sapiens

    EIF2AK3 EIF2AK4 Wee1 WEE1 Pyruvate dehydrogenase kinase (EC 2.7.11.2) PDK1 PDK2 PDK3 PDK4 Dephospho-(reductase kinase) kinase (EC 2.7.11.3) AMP-activated

    GSK3A

    GSK3A

    GSK3A

  • P70-S6 Kinase 1
  • Protein-coding gene in the species Homo sapiens

    EIF2AK3 EIF2AK4 Wee1 WEE1 Pyruvate dehydrogenase kinase (EC 2.7.11.2) PDK1 PDK2 PDK3 PDK4 Dephospho-(reductase kinase) kinase (EC 2.7.11.3) AMP-activated

    P70-S6 Kinase 1

    P70-S6 Kinase 1

    P70-S6_Kinase_1

  • Protein kinase A
  • Family of enzymes

    EIF2AK3 EIF2AK4 Wee1 WEE1 Pyruvate dehydrogenase kinase (EC 2.7.11.2) PDK1 PDK2 PDK3 PDK4 Dephospho-(reductase kinase) kinase (EC 2.7.11.3) AMP-activated

    Protein kinase A

    Protein kinase A

    Protein_kinase_A

  • NLK
  • Mammalian protein found in Homo sapiens

    EIF2AK3 EIF2AK4 Wee1 WEE1 Pyruvate dehydrogenase kinase (EC 2.7.11.2) PDK1 PDK2 PDK3 PDK4 Dephospho-(reductase kinase) kinase (EC 2.7.11.3) AMP-activated

    NLK

    NLK

    NLK

  • P38 mitogen-activated protein kinases
  • Protein family

    EIF2AK3 EIF2AK4 Wee1 WEE1 Pyruvate dehydrogenase kinase (EC 2.7.11.2) PDK1 PDK2 PDK3 PDK4 Dephospho-(reductase kinase) kinase (EC 2.7.11.3) AMP-activated

    P38 mitogen-activated protein kinases

    P38_mitogen-activated_protein_kinases

  • VRK1
  • Protein-coding gene in the species Homo sapiens

    EIF2AK3 EIF2AK4 Wee1 WEE1 Pyruvate dehydrogenase kinase (EC 2.7.11.2) PDK1 PDK2 PDK3 PDK4 Dephospho-(reductase kinase) kinase (EC 2.7.11.3) AMP-activated

    VRK1

    VRK1

    VRK1

  • IRAK3
  • EIF2AK3 EIF2AK4 Wee1 WEE1 Pyruvate dehydrogenase kinase (EC 2.7.11.2) PDK1 PDK2 PDK3 PDK4 Dephospho-(reductase kinase) kinase (EC 2.7.11.3) AMP-activated

    IRAK3

    IRAK3

    IRAK3

  • MTOR inhibitors
  • Class of pharmaceutical drugs

    EIF2AK3 EIF2AK4 Wee1 WEE1 Pyruvate dehydrogenase kinase (EC 2.7.11.2) PDK1 PDK2 PDK3 PDK4 Dephospho-(reductase kinase) kinase (EC 2.7.11.3) AMP-activated

    MTOR inhibitors

    MTOR inhibitors

    MTOR_inhibitors

  • CAMK
  • Enzyme type

    EIF2AK3 EIF2AK4 Wee1 WEE1 Pyruvate dehydrogenase kinase (EC 2.7.11.2) PDK1 PDK2 PDK3 PDK4 Dephospho-(reductase kinase) kinase (EC 2.7.11.3) AMP-activated

    CAMK

    CAMK

  • WNK3
  • Protein-coding gene in the species Homo sapiens

    EIF2AK3 EIF2AK4 Wee1 WEE1 Pyruvate dehydrogenase kinase (EC 2.7.11.2) PDK1 PDK2 PDK3 PDK4 Dephospho-(reductase kinase) kinase (EC 2.7.11.3) AMP-activated

    WNK3

    WNK3

    WNK3

  • VRK2
  • Protein-coding gene in the species Homo sapiens

    EIF2AK3 EIF2AK4 Wee1 WEE1 Pyruvate dehydrogenase kinase (EC 2.7.11.2) PDK1 PDK2 PDK3 PDK4 Dephospho-(reductase kinase) kinase (EC 2.7.11.3) AMP-activated

    VRK2

    VRK2

    VRK2

  • PIK3R4
  • Protein-coding gene in the species Homo sapiens

    EIF2AK3 EIF2AK4 Wee1 WEE1 Pyruvate dehydrogenase kinase (EC 2.7.11.2) PDK1 PDK2 PDK3 PDK4 Dephospho-(reductase kinase) kinase (EC 2.7.11.3) AMP-activated

    PIK3R4

    PIK3R4

    PIK3R4

  • Receptor protein serine/threonine kinase
  • Class of enzymes

    EIF2AK3 EIF2AK4 Wee1 WEE1 Pyruvate dehydrogenase kinase (EC 2.7.11.2) PDK1 PDK2 PDK3 PDK4 Dephospho-(reductase kinase) kinase (EC 2.7.11.3) AMP-activated

    Receptor protein serine/threonine kinase

    Receptor_protein_serine/threonine_kinase

  • NEK6
  • Protein-coding gene in the species Homo sapiens

    is mediated by 3-phosphoinositide-dependent protein kinase-1 (PDK1) and PDK2". Biochem. J. 339 ( Pt 2) (2): 319–28. doi:10.1042/0264-6021:3390319. PMC 1220160

    NEK6

    NEK6

    NEK6

  • Polycystin 2
  • Protein and coding gene in humans

    induced by a cytosine insertion in the polycystic kidney disease 2 gene (PDK2)". Human Molecular Genetics. 6 (6): 949–952. doi:10.1093/hmg/6.6.949. PMID 9175744

    Polycystin 2

    Polycystin 2

    Polycystin_2

  • GAK (protein)
  • Protein-coding gene in the species Homo sapiens

    EIF2AK3 EIF2AK4 Wee1 WEE1 Pyruvate dehydrogenase kinase (EC 2.7.11.2) PDK1 PDK2 PDK3 PDK4 Dephospho-(reductase kinase) kinase (EC 2.7.11.3) AMP-activated

    GAK (protein)

    GAK (protein)

    GAK_(protein)

  • Phototropin
  • Class of photoreceptor proteins in plants

    EIF2AK3 EIF2AK4 Wee1 WEE1 Pyruvate dehydrogenase kinase (EC 2.7.11.2) PDK1 PDK2 PDK3 PDK4 Dephospho-(reductase kinase) kinase (EC 2.7.11.3) AMP-activated

    Phototropin

    Phototropin

  • Pyruvate dehydrogenase lipoamide kinase isozyme 1
  • Protein-coding gene in the species Homo sapiens

    Dehydrogenase Kinase that have been shown to phosphorylate these three sites: PDK1, PDK2, PDK3, and PDK4. PDK1 is the only enzyme capable of phosphorylating the 3rd

    Pyruvate dehydrogenase lipoamide kinase isozyme 1

    Pyruvate dehydrogenase lipoamide kinase isozyme 1

    Pyruvate_dehydrogenase_lipoamide_kinase_isozyme_1

  • RAF kinase
  • EIF2AK3 EIF2AK4 Wee1 WEE1 Pyruvate dehydrogenase kinase (EC 2.7.11.2) PDK1 PDK2 PDK3 PDK4 Dephospho-(reductase kinase) kinase (EC 2.7.11.3) AMP-activated

    RAF kinase

    RAF kinase

    RAF_kinase

  • MAPK1
  • Protein-coding gene in the species Homo sapiens

    EIF2AK3 EIF2AK4 Wee1 WEE1 Pyruvate dehydrogenase kinase (EC 2.7.11.2) PDK1 PDK2 PDK3 PDK4 Dephospho-(reductase kinase) kinase (EC 2.7.11.3) AMP-activated

    MAPK1

    MAPK1

    MAPK1

  • MTORC2
  • Protein complex

    EIF2AK3 EIF2AK4 Wee1 WEE1 Pyruvate dehydrogenase kinase (EC 2.7.11.2) PDK1 PDK2 PDK3 PDK4 Dephospho-(reductase kinase) kinase (EC 2.7.11.3) AMP-activated

    MTORC2

    MTORC2

  • MAPK8
  • Protein-coding gene in the species Homo sapiens

    EIF2AK3 EIF2AK4 Wee1 WEE1 Pyruvate dehydrogenase kinase (EC 2.7.11.2) PDK1 PDK2 PDK3 PDK4 Dephospho-(reductase kinase) kinase (EC 2.7.11.3) AMP-activated

    MAPK8

    MAPK8

    MAPK8

  • ACVRL1
  • Protein-coding gene in humans

    EIF2AK3 EIF2AK4 Wee1 WEE1 Pyruvate dehydrogenase kinase (EC 2.7.11.2) PDK1 PDK2 PDK3 PDK4 Dephospho-(reductase kinase) kinase (EC 2.7.11.3) AMP-activated

    ACVRL1

    ACVRL1

    ACVRL1

  • DAPK1
  • Protein-coding gene in the species Homo sapiens

    EIF2AK3 EIF2AK4 Wee1 WEE1 Pyruvate dehydrogenase kinase (EC 2.7.11.2) PDK1 PDK2 PDK3 PDK4 Dephospho-(reductase kinase) kinase (EC 2.7.11.3) AMP-activated

    DAPK1

    DAPK1

    DAPK1

  • PKN2
  • Protein-coding gene in the species Homo sapiens

    EIF2AK3 EIF2AK4 Wee1 WEE1 Pyruvate dehydrogenase kinase (EC 2.7.11.2) PDK1 PDK2 PDK3 PDK4 Dephospho-(reductase kinase) kinase (EC 2.7.11.3) AMP-activated

    PKN2

    PKN2

    PKN2

  • Myosin light-chain kinase
  • Class of kinase enzymes

    EIF2AK3 EIF2AK4 Wee1 WEE1 Pyruvate dehydrogenase kinase (EC 2.7.11.2) PDK1 PDK2 PDK3 PDK4 Dephospho-(reductase kinase) kinase (EC 2.7.11.3) AMP-activated

    Myosin light-chain kinase

    Myosin light-chain kinase

    Myosin_light-chain_kinase

  • BMPR1A
  • Bone morphogenetic protein receptor

    EIF2AK3 EIF2AK4 Wee1 WEE1 Pyruvate dehydrogenase kinase (EC 2.7.11.2) PDK1 PDK2 PDK3 PDK4 Dephospho-(reductase kinase) kinase (EC 2.7.11.3) AMP-activated

    BMPR1A

    BMPR1A

    BMPR1A

  • BCKDK
  • Protein-coding gene in the species Homo sapiens

    EIF2AK3 EIF2AK4 Wee1 WEE1 Pyruvate dehydrogenase kinase (EC 2.7.11.2) PDK1 PDK2 PDK3 PDK4 Dephospho-(reductase kinase) kinase (EC 2.7.11.3) AMP-activated

    BCKDK

    BCKDK

    BCKDK

  • GSK-3
  • Class of enzymes

    EIF2AK3 EIF2AK4 Wee1 WEE1 Pyruvate dehydrogenase kinase (EC 2.7.11.2) PDK1 PDK2 PDK3 PDK4 Dephospho-(reductase kinase) kinase (EC 2.7.11.3) AMP-activated

    GSK-3

    GSK-3

    GSK-3

  • MAP3K14
  • Protein-coding gene in the species Homo sapiens

    EIF2AK3 EIF2AK4 Wee1 WEE1 Pyruvate dehydrogenase kinase (EC 2.7.11.2) PDK1 PDK2 PDK3 PDK4 Dephospho-(reductase kinase) kinase (EC 2.7.11.3) AMP-activated

    MAP3K14

    MAP3K14

    MAP3K14

  • Calamochrous chilonalis
  • Species of moth

    Taxon identifiers Calamochrous chilonalis Wikidata: Q13447997 CoL: PDK2 EoL: 272530 GBIF: 1888261 Insecta.pro: 40022 IRMNG: 10703259 LepIndex: 21241 Open

    Calamochrous chilonalis

    Calamochrous_chilonalis

  • MYLK2
  • Protein-coding gene in the species Homo sapiens

    EIF2AK3 EIF2AK4 Wee1 WEE1 Pyruvate dehydrogenase kinase (EC 2.7.11.2) PDK1 PDK2 PDK3 PDK4 Dephospho-(reductase kinase) kinase (EC 2.7.11.3) AMP-activated

    MYLK2

    MYLK2

    MYLK2

  • IKK2
  • Protein-coding gene in the species Homo sapiens

    EIF2AK3 EIF2AK4 Wee1 WEE1 Pyruvate dehydrogenase kinase (EC 2.7.11.2) PDK1 PDK2 PDK3 PDK4 Dephospho-(reductase kinase) kinase (EC 2.7.11.3) AMP-activated

    IKK2

    IKK2

    IKK2

  • SGK
  • Protein family

    EIF2AK3 EIF2AK4 Wee1 WEE1 Pyruvate dehydrogenase kinase (EC 2.7.11.2) PDK1 PDK2 PDK3 PDK4 Dephospho-(reductase kinase) kinase (EC 2.7.11.3) AMP-activated

    SGK

    SGK

  • FAM214A
  • Protein-coding gene in the species Homo sapiens

    a review article by Fayard et al., phosphoinositide-dependent kinase 2 (PDK2) is a serine/threonine kinase that is important for regulating cell cycle

    FAM214A

    FAM214A

    FAM214A

  • IKBKG
  • Protein-coding gene in humans

    EIF2AK3 EIF2AK4 Wee1 WEE1 Pyruvate dehydrogenase kinase (EC 2.7.11.2) PDK1 PDK2 PDK3 PDK4 Dephospho-(reductase kinase) kinase (EC 2.7.11.3) AMP-activated

    IKBKG

    IKBKG

    IKBKG

  • EIF2AK3
  • Human protein and coding gene

    EIF2AK3 EIF2AK4 Wee1 WEE1 Pyruvate dehydrogenase kinase (EC 2.7.11.2) PDK1 PDK2 PDK3 PDK4 Dephospho-(reductase kinase) kinase (EC 2.7.11.3) AMP-activated

    EIF2AK3

    EIF2AK3

    EIF2AK3

  • Cyclin-dependent kinase 8
  • Protein-coding gene in the species Homo sapiens

    EIF2AK3 EIF2AK4 Wee1 WEE1 Pyruvate dehydrogenase kinase (EC 2.7.11.2) PDK1 PDK2 PDK3 PDK4 Dephospho-(reductase kinase) kinase (EC 2.7.11.3) AMP-activated

    Cyclin-dependent kinase 8

    Cyclin-dependent kinase 8

    Cyclin-dependent_kinase_8

  • LATS1
  • Protein-coding gene in the species Homo sapiens

    EIF2AK3 EIF2AK4 Wee1 WEE1 Pyruvate dehydrogenase kinase (EC 2.7.11.2) PDK1 PDK2 PDK3 PDK4 Dephospho-(reductase kinase) kinase (EC 2.7.11.3) AMP-activated

    LATS1

    LATS1

    LATS1

  • PRKAG2
  • Protein-coding gene in the species Homo sapiens

    EIF2AK3 EIF2AK4 Wee1 WEE1 Pyruvate dehydrogenase kinase (EC 2.7.11.2) PDK1 PDK2 PDK3 PDK4 Dephospho-(reductase kinase) kinase (EC 2.7.11.3) AMP-activated

    PRKAG2

    PRKAG2

    PRKAG2

  • TGF beta receptor
  • Protein family

    EIF2AK3 EIF2AK4 Wee1 WEE1 Pyruvate dehydrogenase kinase (EC 2.7.11.2) PDK1 PDK2 PDK3 PDK4 Dephospho-(reductase kinase) kinase (EC 2.7.11.3) AMP-activated

    TGF beta receptor

    TGF_beta_receptor

  • CGMP-dependent protein kinase
  • Protein kinase

    EIF2AK3 EIF2AK4 Wee1 WEE1 Pyruvate dehydrogenase kinase (EC 2.7.11.2) PDK1 PDK2 PDK3 PDK4 Dephospho-(reductase kinase) kinase (EC 2.7.11.3) AMP-activated

    CGMP-dependent protein kinase

    CGMP-dependent protein kinase

    CGMP-dependent_protein_kinase

  • MAPK3
  • Protein-coding gene in the species Homo sapiens

    EIF2AK3 EIF2AK4 Wee1 WEE1 Pyruvate dehydrogenase kinase (EC 2.7.11.2) PDK1 PDK2 PDK3 PDK4 Dephospho-(reductase kinase) kinase (EC 2.7.11.3) AMP-activated

    MAPK3

    MAPK3

    MAPK3

  • Ataxia telangiectasia and Rad3 related
  • Protein kinase that detects DNA damage and halts cell division

    EIF2AK3 EIF2AK4 Wee1 WEE1 Pyruvate dehydrogenase kinase (EC 2.7.11.2) PDK1 PDK2 PDK3 PDK4 Dephospho-(reductase kinase) kinase (EC 2.7.11.3) AMP-activated

    Ataxia telangiectasia and Rad3 related

    Ataxia telangiectasia and Rad3 related

    Ataxia_telangiectasia_and_Rad3_related

  • G protein-coupled receptor kinase 2
  • Enzyme

    EIF2AK3 EIF2AK4 Wee1 WEE1 Pyruvate dehydrogenase kinase (EC 2.7.11.2) PDK1 PDK2 PDK3 PDK4 Dephospho-(reductase kinase) kinase (EC 2.7.11.3) AMP-activated

    G protein-coupled receptor kinase 2

    G protein-coupled receptor kinase 2

    G_protein-coupled_receptor_kinase_2

  • ZAK
  • Protein-coding gene in the species Homo sapiens

    EIF2AK3 EIF2AK4 Wee1 WEE1 Pyruvate dehydrogenase kinase (EC 2.7.11.2) PDK1 PDK2 PDK3 PDK4 Dephospho-(reductase kinase) kinase (EC 2.7.11.3) AMP-activated

    ZAK

    ZAK

    ZAK

  • ACVR2B
  • Protein-coding gene in humans

    EIF2AK3 EIF2AK4 Wee1 WEE1 Pyruvate dehydrogenase kinase (EC 2.7.11.2) PDK1 PDK2 PDK3 PDK4 Dephospho-(reductase kinase) kinase (EC 2.7.11.3) AMP-activated

    ACVR2B

    ACVR2B

    ACVR2B

  • Acetate kinase
  • Class of enzymes

    EIF2AK3 EIF2AK4 Wee1 WEE1 Pyruvate dehydrogenase kinase (EC 2.7.11.2) PDK1 PDK2 PDK3 PDK4 Dephospho-(reductase kinase) kinase (EC 2.7.11.3) AMP-activated

    Acetate kinase

    Acetate kinase

    Acetate_kinase

  • Phosphorylase kinase
  • Enzyme involved in glycogenolysis

    EIF2AK3 EIF2AK4 Wee1 WEE1 Pyruvate dehydrogenase kinase (EC 2.7.11.2) PDK1 PDK2 PDK3 PDK4 Dephospho-(reductase kinase) kinase (EC 2.7.11.3) AMP-activated

    Phosphorylase kinase

    Phosphorylase kinase

    Phosphorylase_kinase

  • TRIB2
  • Protein-coding gene in the species Homo sapiens

    EIF2AK3 EIF2AK4 Wee1 WEE1 Pyruvate dehydrogenase kinase (EC 2.7.11.2) PDK1 PDK2 PDK3 PDK4 Dephospho-(reductase kinase) kinase (EC 2.7.11.3) AMP-activated

    TRIB2

    TRIB2

    TRIB2

  • Wee1
  • Nuclear protein

    EIF2AK3 EIF2AK4 Wee1 WEE1 Pyruvate dehydrogenase kinase (EC 2.7.11.2) PDK1 PDK2 PDK3 PDK4 Dephospho-(reductase kinase) kinase (EC 2.7.11.3) AMP-activated

    Wee1

    Wee1

    Wee1

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Online names & meanings

  • Awa
  • Girl/Female

    African, Australian

    Awa

    Air; Wind

  • Braz
  • Boy/Male

    Latin

    Braz

    Stutters.

  • Eeswar
  • Boy/Male

    Hindu, Indian

    Eeswar

    God

  • GABBIE
  • Female

    English

    GABBIE

    Pet form of English Gabriela, GABBIE means "man of God" or "warrior of God."

  • Henning
  • Surname or Lastname

    North German, Dutch, and Danish

    Henning

    North German, Dutch, and Danish : from a pet form of Hans or Heinrich.English : in part the German, Dutch, or Danish name (see 1), but possibly in some cases a variant of Scottish Hanning.Norwegian : habitational name from a farm in Trøndelag. The first element is of uncertain origin, possibly from hein ‘whetstone’; the second element is from Old Norse vin ‘meadow’.Swedish : probably of the same origin as 1.

  • Varouna
  • Girl/Female

    Hindi

    Varouna

    Infinite.

  • Rajanikanta
  • Boy/Male

    Hindu

    Rajanikanta

    Lord of night, Moon

  • KYRIAKOS
  • Male

    Greek

    KYRIAKOS

    (Κυριάκος) Greek name KYRIAKOS means "of the lord."

  • Heaphy
  • Surname or Lastname

    Irish (especially County Waterford)

    Heaphy

    Irish (especially County Waterford) : Anglicized form of Gaelic Ó hÉamhthaigh ‘descendant of Éamhthach’, an adjective meaning ‘swift’.English : habitational name from Heapey in Lancashire, named in Old English as ‘(rose)hip hedge or enclosure’, hēope ‘hip’ + hege ‘hedge’ or gehæg ‘enclosure’.

  • Layina
  • Girl/Female

    Arabic, Muslim

    Layina

    Tender; Supple; Resilient

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