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IKK2

  • IKK2

    • Protein-coding gene in the species Homo sapiens

    treatment of inflammatory diseases and cancer. The small-molecule inhibitor of IKK2 SAR113945, developed by Sanofi-Aventis, was evaluated in patients with knee

    IKK2

    IKK2

    IKK2

  • NF-κB

    • Family of transcription factor protein complexes

    lymphoid organs. In contrast to the canonical signaling that relies on NEMO-IKK2 mediated degradation of IκBα, -β, -ε, non-canonical signaling depends on

    NF-κB

    NF-κB

    NF-κB

  • Hydroxyproline

    • Chemical compound

    targeting for proteasome degradation. DYRK1A, DYRK1B, protein kinase B, eEF2, IKK2, p53, FOXO3A, CEP192 are also reportedly hydroxylated by PHD1. p53 and MAPH6

    Hydroxyproline

    Hydroxyproline

    Hydroxyproline

  • Titin

    • Largest known protein in human muscles

    Goodpasture-antigen-binding protein kinase (EC 2.7.11.9) - IκB kinase (EC 2.7.11.10) CHUK IKK2 TBK1 IKBKE IKBKG IKBKAP cAMP-dependent protein kinase (EC 2.7.11.11) Protein

    Titin

    Titin

    Titin

  • PKMYT1

    • Protein-coding gene in the species Homo sapiens

    Goodpasture-antigen-binding protein kinase (EC 2.7.11.9) - IκB kinase (EC 2.7.11.10) CHUK IKK2 TBK1 IKBKE IKBKG IKBKAP cAMP-dependent protein kinase (EC 2.7.11.11) Protein

    PKMYT1

    PKMYT1

    PKMYT1

  • SMG1

    • Protein-coding gene in the species Homo sapiens

    Goodpasture-antigen-binding protein kinase (EC 2.7.11.9) - IκB kinase (EC 2.7.11.10) CHUK IKK2 TBK1 IKBKE IKBKG IKBKAP cAMP-dependent protein kinase (EC 2.7.11.11) Protein

    SMG1

    SMG1

    SMG1

  • IkappaB kinase

    • Class of enzymes

    a separate gene: IKK-α (also known as IKK1) (CHUK) IKK-β (also known as IKK2) (IKBKB) IKK-γ (also known as NEMO) (IKBKG) The α- and β-subunits together

    IkappaB kinase

    IkappaB_kinase

  • Protein kinase B

    • Set of three serine threonine-specific protein kinases

    Goodpasture-antigen-binding protein kinase (EC 2.7.11.9) - IκB kinase (EC 2.7.11.10) CHUK IKK2 TBK1 IKBKE IKBKG IKBKAP cAMP-dependent protein kinase (EC 2.7.11.11) Protein

    Protein kinase B

    Protein kinase B

    Protein_kinase_B

  • MTORC1

    • Protein complex

    alpha (TNF-alpha) can induce mTOR activity through IKK beta, also known as IKK2. IKK beta can phosphorylate TSC1 at serine residue 487 and TSC1 at serine

    MTORC1

    MTORC1

    MTORC1

  • MASTL

    • Protein-coding gene in the species Homo sapiens

    Goodpasture-antigen-binding protein kinase (EC 2.7.11.9) - IκB kinase (EC 2.7.11.10) CHUK IKK2 TBK1 IKBKE IKBKG IKBKAP cAMP-dependent protein kinase (EC 2.7.11.11) Protein

    MASTL

    MASTL

    MASTL

  • KSR2

    • Protein-coding gene in the species Homo sapiens

    Goodpasture-antigen-binding protein kinase (EC 2.7.11.9) - IκB kinase (EC 2.7.11.10) CHUK IKK2 TBK1 IKBKE IKBKG IKBKAP cAMP-dependent protein kinase (EC 2.7.11.11) Protein

    KSR2

    KSR2

    KSR2

  • GSK3A

    • Protein-coding gene in the species Homo sapiens

    Goodpasture-antigen-binding protein kinase (EC 2.7.11.9) - IκB kinase (EC 2.7.11.10) CHUK IKK2 TBK1 IKBKE IKBKG IKBKAP cAMP-dependent protein kinase (EC 2.7.11.11) Protein

    GSK3A

    GSK3A

    GSK3A

  • Rho-associated protein kinase

    • Protein family

    Goodpasture-antigen-binding protein kinase (EC 2.7.11.9) - IκB kinase (EC 2.7.11.10) CHUK IKK2 TBK1 IKBKE IKBKG IKBKAP cAMP-dependent protein kinase (EC 2.7.11.11) Protein

    Rho-associated protein kinase

    Rho-associated protein kinase

    Rho-associated_protein_kinase

  • MAP3K14

    • Protein-coding gene in the species Homo sapiens

    interleukin-1 type-I receptor. MAP3K14 has been shown to interact with: CHUK, IKK2, and TRAF2. ENSG00000282637 GRCh38: Ensembl release 89: ENSG00000006062,

    MAP3K14

    MAP3K14

    MAP3K14

  • RELB

    • Protein-coding gene in the species Homo sapiens

    the non-canonical pathway, viz RelB and p52, are controlled by canonical IKK2-IκB-RelA:p50 signalling. Moreover, generation of canonical and non-canonical

    RELB

    RELB

    RELB

  • MAP kinase kinase kinase

    • Class of enzymes

    Goodpasture-antigen-binding protein kinase (EC 2.7.11.9) - IκB kinase (EC 2.7.11.10) CHUK IKK2 TBK1 IKBKE IKBKG IKBKAP cAMP-dependent protein kinase (EC 2.7.11.11) Protein

    MAP kinase kinase kinase

    MAP_kinase_kinase_kinase

  • DNA-PKcs

    • Protein found in humans

    Goodpasture-antigen-binding protein kinase (EC 2.7.11.9) - IκB kinase (EC 2.7.11.10) CHUK IKK2 TBK1 IKBKE IKBKG IKBKAP cAMP-dependent protein kinase (EC 2.7.11.11) Protein

    DNA-PKcs

    DNA-PKcs

    DNA-PKcs

  • BRAF (gene)

    • Protein-coding gene in humans

    Goodpasture-antigen-binding protein kinase (EC 2.7.11.9) - IκB kinase (EC 2.7.11.10) CHUK IKK2 TBK1 IKBKE IKBKG IKBKAP cAMP-dependent protein kinase (EC 2.7.11.11) Protein

    BRAF (gene)

    BRAF (gene)

    BRAF_(gene)

  • Aurora kinase

    • Class of enzymes

    Goodpasture-antigen-binding protein kinase (EC 2.7.11.9) - IκB kinase (EC 2.7.11.10) CHUK IKK2 TBK1 IKBKE IKBKG IKBKAP cAMP-dependent protein kinase (EC 2.7.11.11) Protein

    Aurora kinase

    Aurora_kinase

  • Specialized pro-resolving mediators

    • Cellular molecules that help resolve inflammation

    reactions. PUFA-cyclopentenones may likewise react with the IKK2 component of the cytosolic IKK2-NFκB protein complex thereby inhibiting NFκB from stimulating

    Specialized pro-resolving mediators

    Specialized_pro-resolving_mediators

  • AMP-activated protein kinase

    • Class of enzymes

    Goodpasture-antigen-binding protein kinase (EC 2.7.11.9) - IκB kinase (EC 2.7.11.10) CHUK IKK2 TBK1 IKBKE IKBKG IKBKAP cAMP-dependent protein kinase (EC 2.7.11.11) Protein

    AMP-activated protein kinase

    AMP-activated protein kinase

    AMP-activated_protein_kinase

  • IκBα

    • Protein-coding gene in the species Homo sapiens

    C22orf25, CHUK, DYNLL1, G3BP2, Heterogeneous nuclear ribonucleoprotein A1, IKK2, NFKB1, P53, RELA, RPS6KA1, SUMO4, and Valosin-containing protein. GRCh38:

    IκBα

    IκBα

    IκBα

  • MYLK4

    • Enzyme in humans

    Goodpasture-antigen-binding protein kinase (EC 2.7.11.9) - IκB kinase (EC 2.7.11.10) CHUK IKK2 TBK1 IKBKE IKBKG IKBKAP cAMP-dependent protein kinase (EC 2.7.11.11) Protein

    MYLK4

    MYLK4

    MYLK4

  • IRAK3

    • Goodpasture-antigen-binding protein kinase (EC 2.7.11.9) - IκB kinase (EC 2.7.11.10) CHUK IKK2 TBK1 IKBKE IKBKG IKBKAP cAMP-dependent protein kinase (EC 2.7.11.11) Protein

    IRAK3

    IRAK3

    IRAK3

  • CAMK2B

    • Protein-coding gene in humans

    Goodpasture-antigen-binding protein kinase (EC 2.7.11.9) - IκB kinase (EC 2.7.11.10) CHUK IKK2 TBK1 IKBKE IKBKG IKBKAP cAMP-dependent protein kinase (EC 2.7.11.11) Protein

    CAMK2B

    CAMK2B

    CAMK2B

  • PRKAG2

    • Protein-coding gene in the species Homo sapiens

    Goodpasture-antigen-binding protein kinase (EC 2.7.11.9) - IκB kinase (EC 2.7.11.10) CHUK IKK2 TBK1 IKBKE IKBKG IKBKAP cAMP-dependent protein kinase (EC 2.7.11.11) Protein

    PRKAG2

    PRKAG2

    PRKAG2

  • PRKG1

    • Protein-coding gene in the species Homo sapiens

    Goodpasture-antigen-binding protein kinase (EC 2.7.11.9) - IκB kinase (EC 2.7.11.10) CHUK IKK2 TBK1 IKBKE IKBKG IKBKAP cAMP-dependent protein kinase (EC 2.7.11.11) Protein

    PRKG1

    PRKG1

    PRKG1

  • Akt/PKB signaling pathway

    • Series of biochemical reactions

    promote insulin resistance in response to TNF-(alpha) signaling through IKK2". J Biol Chem. 283 (51): 35375–82. doi:10.1074/jbc.M806480200. PMC 2602883

    Akt/PKB signaling pathway

    Akt/PKB_signaling_pathway

  • PRKY

    • Pseudogene in the species Homo sapiens

    Goodpasture-antigen-binding protein kinase (EC 2.7.11.9) - IκB kinase (EC 2.7.11.10) CHUK IKK2 TBK1 IKBKE IKBKG IKBKAP cAMP-dependent protein kinase (EC 2.7.11.11) Protein

    PRKY

    PRKY

    PRKY

  • Phosphatidylinositol 3-kinase-related kinase

    • Protein family

    Goodpasture-antigen-binding protein kinase (EC 2.7.11.9) - IκB kinase (EC 2.7.11.10) CHUK IKK2 TBK1 IKBKE IKBKG IKBKAP cAMP-dependent protein kinase (EC 2.7.11.11) Protein

    Phosphatidylinositol 3-kinase-related kinase

    Phosphatidylinositol_3-kinase-related_kinase

  • MTOR

    • Mammalian protein found in humans

    Goodpasture-antigen-binding protein kinase (EC 2.7.11.9) - IκB kinase (EC 2.7.11.10) CHUK IKK2 TBK1 IKBKE IKBKG IKBKAP cAMP-dependent protein kinase (EC 2.7.11.11) Protein

    MTOR

    MTOR

    MTOR

  • MAPK3

    • Protein-coding gene in the species Homo sapiens

    Goodpasture-antigen-binding protein kinase (EC 2.7.11.9) - IκB kinase (EC 2.7.11.10) CHUK IKK2 TBK1 IKBKE IKBKG IKBKAP cAMP-dependent protein kinase (EC 2.7.11.11) Protein

    MAPK3

    MAPK3

    MAPK3

  • Tropomyosin kinase

    • Class of enzymes

    Goodpasture-antigen-binding protein kinase (EC 2.7.11.9) - IκB kinase (EC 2.7.11.10) CHUK IKK2 TBK1 IKBKE IKBKG IKBKAP cAMP-dependent protein kinase (EC 2.7.11.11) Protein

    Tropomyosin kinase

    Tropomyosin_kinase

  • Goodpasture-antigen-binding protein kinase

    • Phosphate-transferring enzyme

    Goodpasture-antigen-binding protein kinase (EC 2.7.11.9) - IκB kinase (EC 2.7.11.10) CHUK IKK2 TBK1 IKBKE IKBKG IKBKAP cAMP-dependent protein kinase (EC 2.7.11.11) Protein

    Goodpasture-antigen-binding protein kinase

    Goodpasture-antigen-binding_protein_kinase

  • TRIB2

    • Protein-coding gene in the species Homo sapiens

    Goodpasture-antigen-binding protein kinase (EC 2.7.11.9) - IκB kinase (EC 2.7.11.10) CHUK IKK2 TBK1 IKBKE IKBKG IKBKAP cAMP-dependent protein kinase (EC 2.7.11.11) Protein

    TRIB2

    TRIB2

    TRIB2

  • PHKB

    • Protein-coding gene in the species Homo sapiens

    Goodpasture-antigen-binding protein kinase (EC 2.7.11.9) - IκB kinase (EC 2.7.11.10) CHUK IKK2 TBK1 IKBKE IKBKG IKBKAP cAMP-dependent protein kinase (EC 2.7.11.11) Protein

    PHKB

    PHKB

    PHKB

  • P70-S6 Kinase 1

    • Protein-coding gene in the species Homo sapiens

    Goodpasture-antigen-binding protein kinase (EC 2.7.11.9) - IκB kinase (EC 2.7.11.10) CHUK IKK2 TBK1 IKBKE IKBKG IKBKAP cAMP-dependent protein kinase (EC 2.7.11.11) Protein

    P70-S6 Kinase 1

    P70-S6 Kinase 1

    P70-S6_Kinase_1

  • Protein kinase A

    • Family of enzymes

    Goodpasture-antigen-binding protein kinase (EC 2.7.11.9) - IκB kinase (EC 2.7.11.10) CHUK IKK2 TBK1 IKBKE IKBKG IKBKAP cAMP-dependent protein kinase (EC 2.7.11.11) Protein

    Protein kinase A

    Protein kinase A

    Protein_kinase_A

  • Cyclin-dependent kinase

    • Class of enzymes

    Goodpasture-antigen-binding protein kinase (EC 2.7.11.9) - IκB kinase (EC 2.7.11.10) CHUK IKK2 TBK1 IKBKE IKBKG IKBKAP cAMP-dependent protein kinase (EC 2.7.11.11) Protein

    Cyclin-dependent kinase

    Cyclin-dependent kinase

    Cyclin-dependent_kinase

  • BCKDK

    • Protein-coding gene in the species Homo sapiens

    Goodpasture-antigen-binding protein kinase (EC 2.7.11.9) - IκB kinase (EC 2.7.11.10) CHUK IKK2 TBK1 IKBKE IKBKG IKBKAP cAMP-dependent protein kinase (EC 2.7.11.11) Protein

    BCKDK

    BCKDK

    BCKDK

  • Tumor necrosis factor receptor 1

    • Membrane receptor protein found in humans

    dementia. TNFRSF1A has been shown to interact with: BAG4, CASP10, FADD, IKK2, JAK1, JAK2, PIP4K2B, PSMD2, RIPK1, SUMO1, TRADD TRAF2, TRPC4AP, TNF, and

    Tumor necrosis factor receptor 1

    Tumor necrosis factor receptor 1

    Tumor_necrosis_factor_receptor_1

  • NFKB1

    • Protein-coding gene in humans

    growth. NFKB1 has been shown to interact with: BCL3, C22orf25, HDAC1, HMGA2 IKK2, ITGB3BP, IκBα, LYL1, MAP3K7IP2, MAP3K8, MEN1, NFKB2, NFKBIE, NOTCH1, Nuclear

    NFKB1

    NFKB1

    NFKB1

  • IKBKG

    • Protein-coding gene in humans

    injection. IKBKG has been shown to interact with: BCL10, CDC37, CHUK and IKK2, IRAK1, NCOA3, PPM1B, TANK, TNFAIP3, TRAF3IP2, and TRAF6. GRCh38: Ensembl

    IKBKG

    IKBKG

    IKBKG

  • Cellular neuroscience

    • Branch of neuroscience

    microdomains Cell biology Cell signaling Chemical synapse Dendrite Hair cells IKK2 Neuroendocrinology Neuropharmacology Pyramidal cells Soliton model Synaptotropic

    Cellular neuroscience

    Cellular_neuroscience

  • ASK1

    • Protein found in humans

    Goodpasture-antigen-binding protein kinase (EC 2.7.11.9) - IκB kinase (EC 2.7.11.10) CHUK IKK2 TBK1 IKBKE IKBKG IKBKAP cAMP-dependent protein kinase (EC 2.7.11.11) Protein

    ASK1

    ASK1

    ASK1

  • Protein kinase C

    • Family of enzymes

    Goodpasture-antigen-binding protein kinase (EC 2.7.11.9) - IκB kinase (EC 2.7.11.10) CHUK IKK2 TBK1 IKBKE IKBKG IKBKAP cAMP-dependent protein kinase (EC 2.7.11.11) Protein

    Protein kinase C

    Protein_kinase_C

  • Serine/threonine-specific protein kinase

    • Class of protein kinase enzymes

    Goodpasture-antigen-binding protein kinase (EC 2.7.11.9) - IκB kinase (EC 2.7.11.10) CHUK IKK2 TBK1 IKBKE IKBKG IKBKAP cAMP-dependent protein kinase (EC 2.7.11.11) Protein

    Serine/threonine-specific protein kinase

    Serine/threonine-specific protein kinase

    Serine/threonine-specific_protein_kinase

  • GAK (protein)

    • Protein-coding gene in the species Homo sapiens

    Goodpasture-antigen-binding protein kinase (EC 2.7.11.9) - IκB kinase (EC 2.7.11.10) CHUK IKK2 TBK1 IKBKE IKBKG IKBKAP cAMP-dependent protein kinase (EC 2.7.11.11) Protein

    GAK (protein)

    GAK (protein)

    GAK_(protein)

  • Aurora inhibitor

    • Putative drug class for treating cancer

    Goodpasture-antigen-binding protein kinase (EC 2.7.11.9) - IκB kinase (EC 2.7.11.10) CHUK IKK2 TBK1 IKBKE IKBKG IKBKAP cAMP-dependent protein kinase (EC 2.7.11.11) Protein

    Aurora inhibitor

    Aurora inhibitor

    Aurora_inhibitor

  • RELA

    • Protein-coding gene in the species Homo sapiens

    to targeted phosphorylation of RELA by different kinases. For instance, IKK2 is found to be mainly responsible for phosphorylating serine 536 in monocytes

    RELA

    RELA

    RELA

  • Casein kinase 1, alpha 1

    • Enzyme found in humans

    Goodpasture-antigen-binding protein kinase (EC 2.7.11.9) - IκB kinase (EC 2.7.11.10) CHUK IKK2 TBK1 IKBKE IKBKG IKBKAP cAMP-dependent protein kinase (EC 2.7.11.11) Protein

    Casein kinase 1, alpha 1

    Casein kinase 1, alpha 1

    Casein_kinase_1,_alpha_1

  • BMPR1A

    • Bone morphogenetic protein receptor

    Goodpasture-antigen-binding protein kinase (EC 2.7.11.9) - IκB kinase (EC 2.7.11.10) CHUK IKK2 TBK1 IKBKE IKBKG IKBKAP cAMP-dependent protein kinase (EC 2.7.11.11) Protein

    BMPR1A

    BMPR1A

    BMPR1A

  • Cyclin-dependent kinase 1

    • Mammalian protein found in Homo sapiens

    Goodpasture-antigen-binding protein kinase (EC 2.7.11.9) - IκB kinase (EC 2.7.11.10) CHUK IKK2 TBK1 IKBKE IKBKG IKBKAP cAMP-dependent protein kinase (EC 2.7.11.11) Protein

    Cyclin-dependent kinase 1

    Cyclin-dependent kinase 1

    Cyclin-dependent_kinase_1

  • P38 mitogen-activated protein kinases

    • Protein family

    Goodpasture-antigen-binding protein kinase (EC 2.7.11.9) - IκB kinase (EC 2.7.11.10) CHUK IKK2 TBK1 IKBKE IKBKG IKBKAP cAMP-dependent protein kinase (EC 2.7.11.11) Protein

    P38 mitogen-activated protein kinases

    P38_mitogen-activated_protein_kinases

  • Mitogen-activated protein kinase kinase

    • Kinase enzyme

    Goodpasture-antigen-binding protein kinase (EC 2.7.11.9) - IκB kinase (EC 2.7.11.10) CHUK IKK2 TBK1 IKBKE IKBKG IKBKAP cAMP-dependent protein kinase (EC 2.7.11.11) Protein

    Mitogen-activated protein kinase kinase

    Mitogen-activated_protein_kinase_kinase

  • TGF beta receptor

    • Protein family

    Goodpasture-antigen-binding protein kinase (EC 2.7.11.9) - IκB kinase (EC 2.7.11.10) CHUK IKK2 TBK1 IKBKE IKBKG IKBKAP cAMP-dependent protein kinase (EC 2.7.11.11) Protein

    TGF beta receptor

    TGF_beta_receptor

  • Catenin beta-1

    • Mammalian protein found in humans

    CDK5R1, CHUK, CTNND1, CTNNA1, EGFR, Emerin ESR1 FHL2, GSK3B, HER2/neu, HNF4A, IKK2, LEF1 including transgenically, MAGI1, MUC1, NR5A1, PCAF, PHF17, Plakoglobin

    Catenin beta-1

    Catenin beta-1

    Catenin_beta-1

  • VRK2

    • Protein-coding gene in the species Homo sapiens

    Goodpasture-antigen-binding protein kinase (EC 2.7.11.9) - IκB kinase (EC 2.7.11.10) CHUK IKK2 TBK1 IKBKE IKBKG IKBKAP cAMP-dependent protein kinase (EC 2.7.11.11) Protein

    VRK2

    VRK2

    VRK2

  • IRAK1

    • Protein-coding gene in humans

    IRAK1 has been shown to interact with the following proteins: CHUK IKBKG IKK2, Myd88 NEMO SOCS1 STAT3 TRAF6 UBC, TOLLIP TLR4 IRAK-1 signaling is involved

    IRAK1

    IRAK1

    IRAK1

  • AKT1

    • Protein-coding gene in humans

    Goodpasture-antigen-binding protein kinase (EC 2.7.11.9) - IκB kinase (EC 2.7.11.10) CHUK IKK2 TBK1 IKBKE IKBKG IKBKAP cAMP-dependent protein kinase (EC 2.7.11.11) Protein

    AKT1

    AKT1

    AKT1

  • Mitogen-activated protein kinase

    • P38 mitogen-activated protein kinases

    Goodpasture-antigen-binding protein kinase (EC 2.7.11.9) - IκB kinase (EC 2.7.11.10) CHUK IKK2 TBK1 IKBKE IKBKG IKBKAP cAMP-dependent protein kinase (EC 2.7.11.11) Protein

    Mitogen-activated protein kinase

    Mitogen-activated_protein_kinase

  • 15-Hydroxyeicosatetraenoic acid

    • Chemical compound

    monocytes of the THP1 cell line, 15-oxo-ETE inactivates IKKβ (also known as IKK2) thereby blocking this cell's NF-κB-mediated pro-inflammatory responses (e

    15-Hydroxyeicosatetraenoic acid

    15-Hydroxyeicosatetraenoic acid

    15-Hydroxyeicosatetraenoic_acid

  • Phosphorylase kinase

    • Enzyme involved in glycogenolysis

    Goodpasture-antigen-binding protein kinase (EC 2.7.11.9) - IκB kinase (EC 2.7.11.10) CHUK IKK2 TBK1 IKBKE IKBKG IKBKAP cAMP-dependent protein kinase (EC 2.7.11.11) Protein

    Phosphorylase kinase

    Phosphorylase kinase

    Phosphorylase_kinase

  • CCG-4986

    • Chemical compound

    KS (May 2008). "Interleukin-1beta up-regulates RGS4 through the canonical IKK2/IkappaBalpha/NF-kappaB pathway in rabbit colonic smooth muscle". The Biochemical

    CCG-4986

    CCG-4986

    CCG-4986

  • ATM serine/threonine kinase

    • Mammalian protein found in Homo sapiens

    Goodpasture-antigen-binding protein kinase (EC 2.7.11.9) - IκB kinase (EC 2.7.11.10) CHUK IKK2 TBK1 IKBKE IKBKG IKBKAP cAMP-dependent protein kinase (EC 2.7.11.11) Protein

    ATM serine/threonine kinase

    ATM serine/threonine kinase

    ATM_serine/threonine_kinase

  • MAP kinase kinase kinase kinase

    • Family of proteins

    Goodpasture-antigen-binding protein kinase (EC 2.7.11.9) - IκB kinase (EC 2.7.11.10) CHUK IKK2 TBK1 IKBKE IKBKG IKBKAP cAMP-dependent protein kinase (EC 2.7.11.11) Protein

    MAP kinase kinase kinase kinase

    MAP_kinase_kinase_kinase_kinase

  • Ca2+/calmodulin-dependent protein kinase II

    • Class of enzymes

    Goodpasture-antigen-binding protein kinase (EC 2.7.11.9) - IκB kinase (EC 2.7.11.10) CHUK IKK2 TBK1 IKBKE IKBKG IKBKAP cAMP-dependent protein kinase (EC 2.7.11.11) Protein

    Ca2+/calmodulin-dependent protein kinase II

    Ca2+/calmodulin-dependent protein kinase II

    Ca2+/calmodulin-dependent_protein_kinase_II

  • C-Jun N-terminal kinases

    • Chemical compounds

    Goodpasture-antigen-binding protein kinase (EC 2.7.11.9) - IκB kinase (EC 2.7.11.10) CHUK IKK2 TBK1 IKBKE IKBKG IKBKAP cAMP-dependent protein kinase (EC 2.7.11.11) Protein

    C-Jun N-terminal kinases

    C-Jun N-terminal kinases

    C-Jun_N-terminal_kinases

  • GSK-3

    • Class of enzymes

    Goodpasture-antigen-binding protein kinase (EC 2.7.11.9) - IκB kinase (EC 2.7.11.10) CHUK IKK2 TBK1 IKBKE IKBKG IKBKAP cAMP-dependent protein kinase (EC 2.7.11.11) Protein

    GSK-3

    GSK-3

    GSK-3

  • MAPK1

    • Protein-coding gene in the species Homo sapiens

    Goodpasture-antigen-binding protein kinase (EC 2.7.11.9) - IκB kinase (EC 2.7.11.10) CHUK IKK2 TBK1 IKBKE IKBKG IKBKAP cAMP-dependent protein kinase (EC 2.7.11.11) Protein

    MAPK1

    MAPK1

    MAPK1

  • CDC37

    • Protein-coding gene in humans

    target kinases. CDC37 has been shown to interact with: CDK4, HSP90AA1 IKBKG, IKK2, and STK11. CDC37 consists of three structural domains. The N-terminal domain

    CDC37

    CDC37

    CDC37

  • Cyclin-dependent kinase 5

    • Protein found in humans

    Goodpasture-antigen-binding protein kinase (EC 2.7.11.9) - IκB kinase (EC 2.7.11.10) CHUK IKK2 TBK1 IKBKE IKBKG IKBKAP cAMP-dependent protein kinase (EC 2.7.11.11) Protein

    Cyclin-dependent kinase 5

    Cyclin-dependent kinase 5

    Cyclin-dependent_kinase_5

  • Imd pathway

    • Immune signaling pathway of insects

    orthologue = FADD Key/Ikkγ: human orthologue = NEMO Ird5: human orthologue = IKK2 Relish: human orthologues = p65/p50 and IκB Iap2: human orthologue = cIAP2

    Imd pathway

    Imd pathway

    Imd_pathway

  • CHUK

    • Protein-coding gene in humans

    IKK-α has been shown to interact with: HDAC9, AKT1, CTNNB1, FANCA, IKBKG IKK2, IRAK1, MAP3K14, MAP3K7, MAP3K8, NFKBIA, NCOA3, PPM1B, PRKDC, and TRAF2.

    CHUK

    CHUK

    CHUK

  • CAMK

    • Enzyme type

    Goodpasture-antigen-binding protein kinase (EC 2.7.11.9) - IκB kinase (EC 2.7.11.10) CHUK IKK2 TBK1 IKBKE IKBKG IKBKAP cAMP-dependent protein kinase (EC 2.7.11.11) Protein

    CAMK

    CAMK

  • PLK1

    • Mammalian protein found in Homo sapiens

    Goodpasture-antigen-binding protein kinase (EC 2.7.11.9) - IκB kinase (EC 2.7.11.10) CHUK IKK2 TBK1 IKBKE IKBKG IKBKAP cAMP-dependent protein kinase (EC 2.7.11.11) Protein

    PLK1

    PLK1

    PLK1

  • Nuclear receptor coactivator 3

    • Protein found in humans

    receptor alpha, Estrogen receptor beta, Glucocorticoid receptor, IKBKG, IKK2, Retinoid X receptor alpha. Nuclear Factor Kappa B, GRCh38: Ensembl release

    Nuclear receptor coactivator 3

    Nuclear receptor coactivator 3

    Nuclear_receptor_coactivator_3

  • Extracellular signal-regulated kinases

    • Class of enzymes

    Goodpasture-antigen-binding protein kinase (EC 2.7.11.9) - IκB kinase (EC 2.7.11.10) CHUK IKK2 TBK1 IKBKE IKBKG IKBKAP cAMP-dependent protein kinase (EC 2.7.11.11) Protein

    Extracellular signal-regulated kinases

    Extracellular_signal-regulated_kinases

  • MTOR inhibitors

    • Class of pharmaceutical drugs

    Goodpasture-antigen-binding protein kinase (EC 2.7.11.9) - IκB kinase (EC 2.7.11.10) CHUK IKK2 TBK1 IKBKE IKBKG IKBKAP cAMP-dependent protein kinase (EC 2.7.11.11) Protein

    MTOR inhibitors

    MTOR inhibitors

    MTOR_inhibitors

  • RAF kinase

    • Goodpasture-antigen-binding protein kinase (EC 2.7.11.9) - IκB kinase (EC 2.7.11.10) CHUK IKK2 TBK1 IKBKE IKBKG IKBKAP cAMP-dependent protein kinase (EC 2.7.11.11) Protein

    RAF kinase

    RAF kinase

    RAF_kinase

  • Phosphoinositide-dependent kinase-1

    • Protein-coding gene in the species Homo sapiens

    Goodpasture-antigen-binding protein kinase (EC 2.7.11.9) - IκB kinase (EC 2.7.11.10) CHUK IKK2 TBK1 IKBKE IKBKG IKBKAP cAMP-dependent protein kinase (EC 2.7.11.11) Protein

    Phosphoinositide-dependent kinase-1

    Phosphoinositide-dependent kinase-1

    Phosphoinositide-dependent_kinase-1

  • Protein kinase R

    • Human protein and coding gene

    Goodpasture-antigen-binding protein kinase (EC 2.7.11.9) - IκB kinase (EC 2.7.11.10) CHUK IKK2 TBK1 IKBKE IKBKG IKBKAP cAMP-dependent protein kinase (EC 2.7.11.11) Protein

    Protein kinase R

    Protein kinase R

    Protein_kinase_R

  • TANK-binding kinase 1

    • Protein found in humans

    Goodpasture-antigen-binding protein kinase (EC 2.7.11.9) - IκB kinase (EC 2.7.11.10) CHUK IKK2 TBK1 IKBKE IKBKG IKBKAP cAMP-dependent protein kinase (EC 2.7.11.11) Protein

    TANK-binding kinase 1

    TANK-binding kinase 1

    TANK-binding_kinase_1

  • Ribosomal s6 kinase

    • Family of protein kinases

    Goodpasture-antigen-binding protein kinase (EC 2.7.11.9) - IκB kinase (EC 2.7.11.10) CHUK IKK2 TBK1 IKBKE IKBKG IKBKAP cAMP-dependent protein kinase (EC 2.7.11.11) Protein

    Ribosomal s6 kinase

    Ribosomal s6 kinase

    Ribosomal_s6_kinase

  • PIK3R4

    • Protein-coding gene in the species Homo sapiens

    Goodpasture-antigen-binding protein kinase (EC 2.7.11.9) - IκB kinase (EC 2.7.11.10) CHUK IKK2 TBK1 IKBKE IKBKG IKBKAP cAMP-dependent protein kinase (EC 2.7.11.11) Protein

    PIK3R4

    PIK3R4

    PIK3R4

  • MTORC2

    • Protein complex

    Goodpasture-antigen-binding protein kinase (EC 2.7.11.9) - IκB kinase (EC 2.7.11.10) CHUK IKK2 TBK1 IKBKE IKBKG IKBKAP cAMP-dependent protein kinase (EC 2.7.11.11) Protein

    MTORC2

    MTORC2

  • ACVR1

    • Protein-coding gene

    Goodpasture-antigen-binding protein kinase (EC 2.7.11.9) - IκB kinase (EC 2.7.11.10) CHUK IKK2 TBK1 IKBKE IKBKG IKBKAP cAMP-dependent protein kinase (EC 2.7.11.11) Protein

    ACVR1

    ACVR1

    ACVR1

  • Wee1

    • Nuclear protein

    Goodpasture-antigen-binding protein kinase (EC 2.7.11.9) - IκB kinase (EC 2.7.11.10) CHUK IKK2 TBK1 IKBKE IKBKG IKBKAP cAMP-dependent protein kinase (EC 2.7.11.11) Protein

    Wee1

    Wee1

    Wee1

  • Protein kinase C zeta type

    • Mammalian protein found in Homo sapiens

    Goodpasture-antigen-binding protein kinase (EC 2.7.11.9) - IκB kinase (EC 2.7.11.10) CHUK IKK2 TBK1 IKBKE IKBKG IKBKAP cAMP-dependent protein kinase (EC 2.7.11.11) Protein

    Protein kinase C zeta type

    Protein kinase C zeta type

    Protein_kinase_C_zeta_type

  • Aurora kinase B

    • Protein

    Goodpasture-antigen-binding protein kinase (EC 2.7.11.9) - IκB kinase (EC 2.7.11.10) CHUK IKK2 TBK1 IKBKE IKBKG IKBKAP cAMP-dependent protein kinase (EC 2.7.11.11) Protein

    Aurora kinase B

    Aurora kinase B

    Aurora_kinase_B

  • G protein-coupled receptor kinase

    • Family of protein kinases

    Goodpasture-antigen-binding protein kinase (EC 2.7.11.9) - IκB kinase (EC 2.7.11.10) CHUK IKK2 TBK1 IKBKE IKBKG IKBKAP cAMP-dependent protein kinase (EC 2.7.11.11) Protein

    G protein-coupled receptor kinase

    G protein-coupled receptor kinase

    G_protein-coupled_receptor_kinase

  • G protein-coupled receptor kinase 2

    • Enzyme

    Goodpasture-antigen-binding protein kinase (EC 2.7.11.9) - IκB kinase (EC 2.7.11.10) CHUK IKK2 TBK1 IKBKE IKBKG IKBKAP cAMP-dependent protein kinase (EC 2.7.11.11) Protein

    G protein-coupled receptor kinase 2

    G protein-coupled receptor kinase 2

    G_protein-coupled_receptor_kinase_2

  • ACVR2B

    • Protein-coding gene in humans

    Goodpasture-antigen-binding protein kinase (EC 2.7.11.9) - IκB kinase (EC 2.7.11.10) CHUK IKK2 TBK1 IKBKE IKBKG IKBKAP cAMP-dependent protein kinase (EC 2.7.11.11) Protein

    ACVR2B

    ACVR2B

    ACVR2B

  • Calcium/calmodulin-dependent protein kinase type II subunit alpha

    • Protein found in humans

    Goodpasture-antigen-binding protein kinase (EC 2.7.11.9) - IκB kinase (EC 2.7.11.10) CHUK IKK2 TBK1 IKBKE IKBKG IKBKAP cAMP-dependent protein kinase (EC 2.7.11.11) Protein

    Calcium/calmodulin-dependent protein kinase type II subunit alpha

    Calcium/calmodulin-dependent protein kinase type II subunit alpha

    Calcium/calmodulin-dependent_protein_kinase_type_II_subunit_alpha

  • PPM1B

    • Protein-coding gene in the species Homo sapiens

    sequences. PPM1B has been shown to interact with: CDK2, CDK6, CHUK, IKBKG, IKK2, MAP3K7, and PPARγ. GRCh38: Ensembl release 89: ENSG00000138032 – Ensembl

    PPM1B

    PPM1B

    PPM1B

  • CHEK1

    • Protein-coding gene in humans

    Goodpasture-antigen-binding protein kinase (EC 2.7.11.9) - IκB kinase (EC 2.7.11.10) CHUK IKK2 TBK1 IKBKE IKBKG IKBKAP cAMP-dependent protein kinase (EC 2.7.11.11) Protein

    CHEK1

    CHEK1

    CHEK1

  • VRK1

    • Protein-coding gene in the species Homo sapiens

    Goodpasture-antigen-binding protein kinase (EC 2.7.11.9) - IκB kinase (EC 2.7.11.10) CHUK IKK2 TBK1 IKBKE IKBKG IKBKAP cAMP-dependent protein kinase (EC 2.7.11.11) Protein

    VRK1

    VRK1

    VRK1

  • NLK

    • Mammalian protein found in Homo sapiens

    Goodpasture-antigen-binding protein kinase (EC 2.7.11.9) - IκB kinase (EC 2.7.11.10) CHUK IKK2 TBK1 IKBKE IKBKG IKBKAP cAMP-dependent protein kinase (EC 2.7.11.11) Protein

    NLK

    NLK

    NLK

  • Phototropin

    • Class of photoreceptor proteins in plants

    Goodpasture-antigen-binding protein kinase (EC 2.7.11.9) - IκB kinase (EC 2.7.11.10) CHUK IKK2 TBK1 IKBKE IKBKG IKBKAP cAMP-dependent protein kinase (EC 2.7.11.11) Protein

    Phototropin

    Phototropin

  • Myosin light-chain kinase

    • Class of kinase enzymes

    Goodpasture-antigen-binding protein kinase (EC 2.7.11.9) - IκB kinase (EC 2.7.11.10) CHUK IKK2 TBK1 IKBKE IKBKG IKBKAP cAMP-dependent protein kinase (EC 2.7.11.11) Protein

    Myosin light-chain kinase

    Myosin light-chain kinase

    Myosin_light-chain_kinase

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Online names & meanings

  • Basav | பஸவ 

    • Boy/Male

    Tamil

    Basav | பஸவ 

    Lord of bulls

  • Teji

    • Boy/Male

    Hindu, Indian

    Teji

    Very Fast

  • ARSENII

    • Male

    Russian

    ARSENII

    (Арсе́ний) Russian form of Greek Arsenios, ARSENII means "virile."

  • Jaleel

    • Boy/Male

    Indian

    Jaleel

    Great, Revered

  • Charumati | சாருமதீ

    • Girl/Female

    Tamil

    Charumati | சாருமதீ

    Beautiful mind

  • Cranleah

    • Boy/Male

    Anglo, British, English

    Cranleah

    From the Crane Meadow

  • RASHNE

    • Male

    Iranian/Persian

    RASHNE

    Persian name RASHNE means "judge."

  • BARTHOLD

    • Male

    German

    BARTHOLD

    Variant spelling of German Berthold, BARTHOLD means "bright ruler."

  • Janamejay

    • Boy/Male

    Hindu

    Janamejay

    Lord Vishnu

  • Jessenia

    • Girl/Female

    Muslim/Islamic

    Jessenia

    Flower

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IKK2

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