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Protein family
In molecular biology, origin recognition complex (ORC) is a multi-subunit DNA binding complex (6 subunits) that binds in all eukaryotes and archaea in
Origin_recognition_complex
DNA replication in eukaryotic organisms
assembly of the pre-replication complex (pre-RC) is the binding of the origin recognition complex (ORC) to the replication origin. In late mitosis, the Cdc6
Eukaryotic_DNA_replication
Sequence in a genome
Zhao Y, et al. (July 2018). "Structure of the origin recognition complex bound to DNA replication origin". Nature. 559 (7713): 217–222. Bibcode:2018Natur
Origin_of_replication
Protein-coding gene in the species Homo sapiens
Origin recognition complex subunit 6 is a protein that in humans is encoded by the ORC6 (ORC6L) gene. The origin recognition complex (ORC) is a highly
ORC6
Protein complex formed during initiation of DNA replication
simplified model of the eukaryotic pre-RC. It is composed of a single origin recognition complex (ORC) protein, Cdc6/ORC1, and a homohexamer of the minichromosome
Pre-replication_complex
Biological process
associate with the bound origin recognition complex at the origin in order to form a larger complex necessary to load the Mcm complex onto the DNA. In eukaryotes
DNA_replication
Protein-coding gene in the species Homo sapiens
Origin recognition complex subunit 4 is a protein that in humans is encoded by the ORC4 (ORC4L) gene. The origin recognition complex (ORC) is a highly
ORC4
Protein-coding gene in the species Homo sapiens
Origin recognition complex subunit 3 is a protein that in humans is encoded by the ORC3 (ORC3L) gene. The origin recognition complex (ORC) is a highly
ORC3
Protein-coding gene in the species Homo sapiens
Origin recognition complex subunit 5 is a protein that in humans is encoded by the ORC5 (ORC5L) gene. The origin recognition complex (ORC) is a highly
ORC5
Protein-coding gene in the species Homo sapiens
Origin recognition complex subunit 2 is a protein that is encoded by the ORC2 (ORC2L) gene in humans. The origin recognition complex (ORC) is a highly
ORC2
Chinese-American geneticist and biologist (born c. 1947)
the first high-resolution structures of both the MCM complex and the Origin Recognition Complex (ORC) in 2015 and 2018. Tye is currently a Professor Emeritus
Bik_Kwoon_Tye
Protein found in humans
pre-replication complexes (pre-RC), which occurs during the G1 phase of the cell cycle. In the assembly of pre-RCs, origin recognition complexes (ORC1-6) recognize
DNA_replication_factor_CDT1
Initiation site for the opening of the DNA double helix
by origin recognition complex. DUEs are found in both prokaryotic and eukaryotic organisms, but were first discovered in yeast and bacteria origins, by
DNA_unwinding_element
Protein-coding gene in the species Homo sapiens
Origin recognition complex subunit 1 is a protein that in humans is encoded by the ORC1 gene. It is closely related to CDC6, and both are the same protein
ORC1
proteins to disrupt the H-bonding in that area. ORC protein complex (origin recognition complex) is bound at the ARS throughout the cell cycle, allowing
Autonomously replicating sequence
Autonomously_replicating_sequence
Events leading to cell division
Cellular model Eukaryotic DNA replication Mitotic catastrophe Origin recognition complex Retinoblastoma protein Synchronous culture – synchronization of
Cell_cycle
Molecular complex
Efficient replisome assembly at origins of replication (origin recognition complexes or specific replication origin sequences in some organisms) Separating
Replisome
Protein complex that allows microtubules to attach to chromosomes during cell division
Bub1, Bub3, Mad2 and CENP-E. Orc2 (a protein that belongs to the origin recognition complex -ORC- implicated in DNA replication initiation during S phase)
Kinetochore
DNA region replicating from a single origin
independently replicated from a single origin of replication[citation needed]. A bacterial chromosome contains a single origin, and therefore the whole bacterial
Replicon_(genetics)
Protein family
Site selection for replication origins is carried out by the Origin Recognition Complex (ORC), a six subunit complex (Orc1-6). During the G1 phase of
Minichromosome_maintenance
Medical condition
of MGORS. Pre-replication complex is an important protein complex, which consist of 6 subunits of Origin Recognition Complex (ORC1, ORC2, ORC3, ORC4, ORC5
Meier-Gorlin_syndrome
Molecular biology method
are transcription factors, replication-related proteins, like origin recognition complex protein (ORC), histones, their variants, and histone modifications
ChIP-on-chip
Private, non-profit research institution in US
and elucidation of the mechanism of the Origin Recognition Complex (ORC), a highly conserved protein complex that recognizes and binds to specific DNA
Cold_Spring_Harbor_Laboratory
Topics referred to by the same term
union Organic Rankine Cycle Organized retail crime Origin recognition complex, a protein complex Otago Regional Council, New Zealand Ottawa Rowing Club
Orc_(disambiguation)
Protein-coding gene in humans
of Human Origin Recognition Complex, Cdc6, and Minichromosome Maintenance Proteins during the Cell Cycle: Assembly of Prereplication Complexes in Late
CDC6
in Rrm3p code for a region that binds to Orc5, a domain in an origin recognition complex. The binding of these two proteins appears to be linked to inappropriate
RRM3
Cell-cycle regulatory complex
protein that binds to Cdt1 which prevents its binding to the origin recognition complex (ORC). APCCdh1 targets geminin for ubiquitination throughout G1
Anaphase-promoting_complex
Cell cycle checkpoint
20-50kb. In this direction, Orc2 (one protein included in the origin recognition complex, ORC, implicated in the initiation of DNA replication during S
Spindle_checkpoint
Undesirable occurrence in eukaryotic cells
origin recognition complexes (ORCs) assemble to begin replication. The repetition of these sequences may be the most important to origin recognition.
DNA_re-replication
Automatic conversion of spoken language into text
Speech recognition (automatic speech recognition (ASR), computer speech recognition, or speech-to-text (STT)) is a sub-field of computational linguistics
Speech_recognition
Class of ribonucleic acid that is not translated into proteins
interactions with chromatin and initiation proteins (including the origin recognition complex). They are also components of the Ro60 ribonucleoprotein particle
Non-coding_RNA
Automated recognition of patterns and regularities in data
machine learning. Pattern recognition has its origins in statistics and engineering; some modern approaches to pattern recognition include the use of machine
Pattern_recognition
Large chromosome with thousands of DNA strands
with the active chromatin proteins, nucleosome remodeling, and origin recognition complexes. Their primary functions are: to act as binding sites for RNA
Polytene_chromosome
Protein
unwinding of origin DNA for precise timing. DnaA recognition sites in Escherichia coli are arranged in OriC to facilitate staged pre-replication complex assembling
DnaA
Protein-coding gene in the species Homo sapiens
manner. These histone-fold protein dimers combine within larger enzymatic complexes for DNA transcription, replication, and packaging. GRCh38: Ensembl release
POLE4
Australian biochemist and cancer researcher
was the discovery of the Origin Recognition Complex (ORC), a key protein made up of six subunits that binds to cellular origins of DNA replication and coordinates
Bruce_William_Stillman
RNA family
interactions with chromatin and initiation proteins (including the origin recognition complex) Y RNAs are overexpressed in some human tumours and are required
Y_RNA
Governments' recognition of the Ottoman empire's mass killing of Armenians as genocide
The recognition of the Armenian genocide is the acknowledgement of the fact that the Ottoman Empire's systematic massacres and forced deportation of Armenians
Armenian_genocide_recognition
Protein-coding gene in humans
proteins in human cell lysates. Identification of the human CHL12/RFCs2-5 complex as a novel PCNA-binding protein". J. Biol. Chem. 277 (43): 40362–7. doi:10
POLE_(gene)
Protein family
proteins such as eukaryotic DNA (cytosine-5) methyltransferases, the origin recognition complex 1 (Orc1) proteins, Bromo adjacent homology domain containing 1
BAH_domain
Protein in eukaryotic cells
member of the pre-replicative complex (pre-RC) together with the origin recognition complex (ORC), Cdt1 and the MCM complex (containing MCM2-7p). CDC6 assembles
Cdc6
Protein-coding gene in the species Homo sapiens
encoded by the POLD3 gene. It is a component of the DNA polymerase delta complex. POLD3 has been shown to interact with PCNA. GRCh38: Ensembl release 89:
POLD3
telomeres, rDNA and HM loci. These proteins, including Rap1p and the origin recognition complex (ORC), serve as a platform for other proteins to bind, condense
Ty5_retrotransposon
American biologist
that in yeast and other eukaryotes, this site is adjacent to the origin recognition complex binding site. Her recent research has covered conservation of
Susan_Gerbi
Protein
episomes to the chromosomes. It binds directly to replication origin recognition complexes (ORCs) that are primarily associated with the terminal repeat
LANA
Canadian experimental rock duo
Poitrine (guitar, bass) and Klek de Poitrine (drums). They are known for complex microtonal compositions in the style of math rock and experimental rock
Angine_de_Poitrine
Protein found in humans
Kim SY, Hidaka M, Tansey WP, Stillman B (March 2002). "Human origin recognition complex large subunit is degraded by ubiquitin-mediated proteolysis after
Cyclin-dependent_kinase_2
History of Palestinians
Studies on the origins of the Palestinians, encompassing the Arab inhabitants of the former Mandatory Palestine and their descendants, are approached
Origin_of_the_Palestinians
Protein-coding gene in humans
TA, Walter JC (2002). "MCM2-7 complexes bind chromatin in a distributed pattern surrounding the origin recognition complex in Xenopus egg extracts". J.
MCM2
A licensing factor is a protein or complex of proteins that allows an origin of replication to begin DNA replication at that site. Licensing factors primarily
Licensing_factor
Protein family
methyltransferase, methyl CpG binding protein MeCP2, and the origin recognition complex protein ORC2. HP1 has a versatile structure with three main components;
Heterochromatin_protein_1
American researcher
DNA oncoviruses and in the characterization of the eukaryotic origin recognition complex. "Michael Botchan". Berkeley Research. Retrieved 2017-07-03. "Michael
Michael_Botchan
Protein-coding gene in the species Homo sapiens
Kim SY, Hidaka M, Tansey WP, Stillman B (March 2002). "Human origin recognition complex large subunit is degraded by ubiquitin-mediated proteolysis after
SKP2
Indian biologist (born 1968)
mammalian DNA replication which assisted him to identify the ORC6 (origin recognition complex subunit six) and its role in viral DNA replication. He also identified
Suman_Kumar_Dhar
Genus of protists
the DNA replication proteins of the origin recognition complex (ORC), Cdc6, some components of the GINS complex and some subunits of polymerases delta
Carpediemonas
Long non-coding RNA transcribed from telomeres
with heterochromatin proteins, including HP1α, HP1β, and the origin recognition complex (ORC). These factors are known to play a role in establishment
Telomeric repeat–containing RNA
Telomeric_repeat–containing_RNA
Method of biometric identification
Iris recognition is an automated method of biometric identification that uses mathematical pattern-recognition techniques on video images of one or both
Iris_recognition
Protein found in humans
to part of the pre-RC, the origin recognition complex (ORC). Since Cdc7 is attached to the Dbf4 protein the entire complex is held in place during replication
Cell division cycle 7-related protein kinase
Cell_division_cycle_7-related_protein_kinase
Protein-coding gene in humans
of human origin recognition complex, cdc6, and minichromosome maintenance proteins during the cell cycle: assembly of prereplication complexes in late
MCM3
Protein-coding gene in the species Homo sapiens
Dbf4p mediates interaction with both origin recognition complex (ORC) and Rad53p and can deregulate late origin firing". Proceedings of the National Academy
DBF4
Relationship between language and human evolution
The origin of language, its relationship with human evolution, and its consequences have been subjects of study for centuries. Scholars wishing to study
Origin_of_language
Process which formed the domestic dog
; Walter, R.; Matisoo-Smith, E. (14 June 2018). "Complex history of dog (Canis familiaris) origins and translocations in the Pacific revealed by ancient
Domestication_of_the_dog
Country in East Asia
maintain formal relations with the ROC; but recognition gradually eroded and many countries switched recognition to the People's Republic of China in the
Taiwan
Theory of early hominid migration
the 21st century, the picture of "recent single-origin" migrations has become significantly more complex, due to the discovery of modern-archaic admixture
Recent African origin of modern humans
Recent_African_origin_of_modern_humans
Central question in evolutionary biology of birds
group of animals birds evolved within has traditionally been called the "origin of birds". The present scientific consensus is that birds are a group of
Origin_of_birds
Organelle in eukaryotic cells responsible for respiration
Mitochondrion. Lane N (2016). The Vital Question: Energy, Evolution, and the Origins of Complex Life. WW Norton & Company. ISBN 978-0-393-35297-9. Powering the Cell
Mitochondrion
Cell surface proteins, part of the acquired immune system
microglobulin provides stability of the complex and participates in the recognition of peptide-MHC class I complex by CD8 co-receptor. The peptide is non-covalently
Major histocompatibility complex
Major_histocompatibility_complex
Optical character recognition technology
Automatic number-plate recognition (ANPR; see also other names below) is a technology that uses optical character recognition on images to read vehicle
Automatic number-plate recognition
Automatic_number-plate_recognition
Fictional character
even over great distances. Madigan's performance received widespread recognition during the awards season. She won the Academy Award for Best Supporting
Aunt_Gladys
Family of cell surface receptors
and phylogenetic origin. Generally there is a large group, which recognizes and binds carbohydrates, so called carbohydrate recognition domains (CRDs) and
Pattern_recognition_receptor
Unpleasant emotion
evaluating the possible presence of an underlying medical cause, the recognition of which is essential in order to decide the correct treatment. Anxiety
Anxiety
Cognitive process of visually interpreting the human face
communicate through body language. Developing facial recognition is a necessary building block for complex societal constructs. Being able to perceive identity
Face_perception
Overview of the early history of Judaism
widespread belief among archeological and historical scholars is that the origins of Judaism lie in the Persian province of Yehud. Judaism evolved from the
Origins_of_Judaism
Country in northern Europe
television in Sweden started in 1999. Sweden has many authors of worldwide recognition including August Strindberg, Astrid Lindgren, and Nobel Prize winners
Sweden
Russian fashion model (born 1986)
is a Russian fashion model and actress. She received international recognition when she appeared as the first Russian model on the cover of the 2011
Irina_Shayk
Family of ethnic groups of Eurasia
of both East Asian and West-Eurasian physical appearances and genetic origins, in part through long-term contact with neighboring peoples such as Iranic
Turkic_peoples
Canadian rapper and singer (born 1986)
sensibilities in hip-hop music through rap-singing. Drake first gained recognition as Jimmy Brooks in the CTV teen drama series Degrassi: The Next Generation
Drake_(musician)
Nations Security Council (UNSC) to the PRC in 1971. As international recognition of the ROC continues to dwindle concurrently with the PRC's rise as a
Foreign_relations_of_Taiwan
Classification of music by tradition or style
cultural context, and the content and spirit of the themes. Geographical origin is sometimes used to identify a music genre, though a single geographical
Music_genre
Model of evolutionary neurology proposed by Paul McLean
consists of the reptilian complex (basal ganglia), the paleomammalian complex (limbic system), and the neomammalian complex (neocortex), viewed each as
Triune_brain
Class of enzymes which cleave nucleic acids
entails a degree of recognition. Nucleases variously employ both nonspecific and specific associations in their modes of recognition and binding. Both modes
Nuclease
Change in the heritable traits of populations
ratcheting, and it has been applied in areas ranging from the origins of the spliceosome to the complex interdependence of microbial communities. The time it
Evolution
American actress (born 1995)
Pedretti (born March 23, 1995) is an American actress. She gained wide recognition for starring in the Netflix horror series The Haunting of Hill House
Victoria_Pedretti
Country in South Asia
unification of Nepal, the Kathmandu Valley was known as Nepal. The precise origin of the term Nepāl is uncertain. Nepal appears in ancient Indian literary
Nepal
Islamist Palestinian political and paramilitary organization
signal a recognition of Israel. A Hamas official said that having an indefinite truce with Israel doesn't contradict Hamas's lack of recognition of Israel
Hamas
2017 German science-fiction television series
resulted in awards, but Louis Hofmann received the "Best Newcomer" award in recognition of his lead role in Dark as well as his performances in several films
Dark_(TV_series)
Emotion modeling in AI
In the early days of AI-based detection (speech recognition, face recognition, and affect recognition), the accuracy of modeling and tracking was an issue
Affective_computing
Basic unit of taxonomic classification, below genus
time. Later biologists have tried to refine Mayr's definition with the recognition and cohesion concepts, among others. Many of the concepts are quite similar
Species
Type of stable macromolecular complex
A protein complex or multiprotein complex is a group of two or more associated polypeptide chains. Protein complexes are distinct from multidomain enzymes
Protein_complex
Sex-specific adaptations
from ornamentation offsets its cost to produce or maintain, suggesting complex evolutionary implications, but the costs and evolutionary implications
Sexual_dimorphism
US–USSR spaceflight capability rivalry
the Soviet Union, to achieve superior spaceflight capability. It had its origins in the ballistic missile-based nuclear arms race between the two nations
Space_Race
European archaeological culture, 2800–1800 BC
for merging. › The Bell Beaker culture, also known as the Bell Beaker complex or Bell Beaker phenomenon, is an archaeological culture named after the
Bell_Beaker_culture
Bacterium, genetic engineering tool
and related species, collectively the Agrobacterium tumefaciens species complex, has greatly outpaced the change in terminology employed by plant scientists
Agrobacterium_tumefaciens
Ability of an organism to distinguish between close genetic kin and non-kin
recent common origin. Since kin selection theory emerged, much research has been produced investigating the possible role of kin recognition mechanisms in
Kin_recognition
Technological phenomenon with social implications
socioeconomic, and gender biases. The relative inability of facial recognition technology to accurately identify darker-skinned faces has been linked
Algorithmic_bias
Aqueous phase rich in macromolecules
reawakening of coacervate research was seen in the 2000s, starting with the recognition in 2004 by scientists at the University of California, Santa Barbara
Coacervate
Old Stone Age ''Homo sapiens''
recently dated, ca. 233,000 years ago). An mtDNA study in 2019 proposed an origin of modern humans in Botswana (and a Khoisan split) of around 200,000 years
Early_modern_human
Group of islands in the South Atlantic
blue shorts). They had a very basic pitch on American Field, named in recognition of the American forces stationed there during World War II. However,
Tristan_da_Cunha
Type of therapy to improve mental health
Beck's original treatment manual for depression states, "The philosophical origins of cognitive therapy can be traced back to the Stoic philosophers". Another
Cognitive_behavioral_therapy
Protein involved in processing RNA in animal cells
cofactors interacting with the microprocessor complex. The loop region of the pri-miRNA stem-loop is also a recognition element for regulatory proteins, which
Microprocessor_complex
ORIGIN RECOGNITION-COMPLEX
ORIGIN RECOGNITION-COMPLEX
Surname or Lastname
English (of Welsh origin)
English (of Welsh origin) : variant of Maddox.
Male
Greek
Short form of Greek Origenes, probably ORIGEN means "mountain-born."
Male
English
Variant spelling of English Oran, ORRIN means "little sallow one."
Boy/Male
Arabic, Australian, Muslim
Mount of Recognition; Pilgrimage Site 25km from Mecca
Boy/Male
Arabic, Muslim
Praise; Hymn of God; Recognition
Surname or Lastname
English (of Welsh origin)
English (of Welsh origin) : variant of Maddox.
Surname or Lastname
English (of Welsh origin)
English (of Welsh origin) : variant of Maddock.
Surname or Lastname
English (of Norman origin)
English (of Norman origin) : see Mainwaring.
Surname or Lastname
English (of Welsh origin)
English (of Welsh origin) : variant of Maddox.
Boy/Male
Greek American
Rising in the sky; dawning. Mythological Orion was a mighty hunter and son of Poseidon. The...
Surname or Lastname
English (of Welsh origin)
English (of Welsh origin) : variant of Maddox.
Female
Norwegian
Norwegian variant spelling of Scandinavian Birgit, BRIGIT means "exalted one."
Girl/Female
Irish
The name Brigid from brigh meaning “power, vigour, virtue†epitomizes the Irish genius for layering old and new. The main female deity of the Celts, Brigid made the land fruitful and animals multiply, she blessed poets and blacksmiths. Her namesake St. Brigid of Kildare carried her powers into the Christian era. The stories of Brigidâ€s compassion and miracles are told now as they have been for more than 1500 years in every part of Ireland. She is equal in esteem and shares a grave with St. Patrick and St. Columcille. Her feast day, February 1st, is the first day of Spring in the Celtic calender.
Surname or Lastname
English (of Welsh origin)
English (of Welsh origin) : variant of Maddox.
Male
English
Anglicized form of Middle Welsh Urien, ORIAN means "privileged birth."
Surname or Lastname
English (of Welsh origin)
English (of Welsh origin) : variant of Maddox.
Surname or Lastname
English (of Welsh origin)
English (of Welsh origin) : variant of Maddox.
Male
Greek
(ΩÏίων) Greek name, probably ORION means "mountain man." But some sources say that the name may actually be of Akkadian origin; if so, it means "light of heaven." In mythology, this is the name of one of the Titan gods, a primordial hunter who was killed by a scorpion. A constellation was named after him. Orion had two dogs; their names were: Arktophonos and Ptoophagos.Â
Girl/Female
French, German, Latin
Virgin
Boy/Male
Afghan, German, Indonesian
Fulfilled Wish; Prayer; Recognition; Acceptance
ORIGIN RECOGNITION-COMPLEX
ORIGIN RECOGNITION-COMPLEX
Girl/Female
Gujarati, Indian
God Like
Boy/Male
Tamil
King, Arjun
Boy/Male
Hindu, Indian, Punjabi, Sikh
Lucky
Male
French
A derivative of Anglo-Norman French Jehan, JEAN means "God is gracious." Compare with feminine Jean.
Boy/Male
British, English
From the Large Fields or Granta's Fields
Girl/Female
Muslim
Everlasting happiness, Illumination
Boy/Male
Hebrew American
Jehovah has given. In the bible Jonathan son of King Saul was noted for manliness; generosity and...
Boy/Male
Biblical
The Lord will provide.
Girl/Female
American, Arabic, Australian, Latin
Dedicated to God Mars; Lady; Feminine of Martin; Warlike
Male
English
Anglicized form of Hebrew Achiyam, AHIAM means "mother's brother," i.e. "uncle." In the bible, this is the name of one of King David's warriors.
ORIGIN RECOGNITION-COMPLEX
ORIGIN RECOGNITION-COMPLEX
ORIGIN RECOGNITION-COMPLEX
ORIGIN RECOGNITION-COMPLEX
ORIGIN RECOGNITION-COMPLEX
n.
Fig.: Sympathetic recognition; response; answer.
a.
Cold; wanting heat or warmth; of low temperature; as, a frigid climate.
a.
Pure; undefiled; unmixed; fresh; new; as, virgin soil; virgin gold.
a.
First in order; primary; original; of earliest origin; as, primordial condition.
a.
Before unused or unknown; new; as, a book full of original matter.
n.
A failure to recognize; absence of recognition.
a.
Pertaining to the origin or beginning; preceding all others; first in order; primitive; primary; pristine; as, the original state of man; the original laws of a country; the original inventor of a process.
n.
The act of recognizing, or the state of being recognized; acknowledgment; formal avowal; knowledge confessed or avowed; notice.
a.
Not copied, imitated, or translated; new; fresh; genuine; as, an original thought; an original process; the original text of Scripture.
a.
Being a virgin; chaste; of or pertaining to a virgin; becoming a virgin; maidenly; modest; indicating modesty; as, a virgin blush.
n.
An original thinker or writer; an originator.
n.
Origin; commencement; source.
n.
Official recognition or permission.
n.
Recollection; recognition.
n.
Recognition.
a.
Hence, not lax or indulgent; severe; inflexible; strict; as, a rigid father or master; rigid discipline; rigid criticism; a rigid sentence.
a.
Wanting warmth, fervor, ardor, fire, vivacity, etc.; unfeeling; forbidding in manner; dull and unanimated; stiff and formal; as, a frigid constitution; a frigid style; a frigid look or manner; frigid obedience or service.
a.
Pertaining to, or connected with, recognition.
n.
Previous cognition.
a.
Pertaining to a font, fountain, source, or origin; original; primitive.