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Protoplasm that permeates a cell's nucleus
The nucleoplasm, also known as karyoplasm, is the type of protoplasm that makes up the cell nucleus, the most prominent organelle of the eukaryotic cell
Nucleoplasm
Alternative term for cytoplasm or cytoplasm and nucleoplasm
the cytoplasm (e.g., Mohl, 1846), but for others, it also includes the nucleoplasm (e.g., Strasburger, 1882). For Sharp (1921), "According to the older
Protoplasm
All of the contents of a cell including organelles but excluding the nucleus
eukaryotic cell and contained within the nuclear membrane is termed the nucleoplasm. The main components of the cytoplasm are the cytosol (a gel-like substance)
Cytoplasm
Organelle in eukaryotic cells
nuclear envelope separates the fluid inside the nucleus, called the nucleoplasm, from the rest of the cell. The size of the nucleus is correlated to
Cell_nucleus
Type of double-walled membrane
envelope. Similar membranes are found in both the cytoplasm and nucleoplasm. In the nucleoplasm, they are small, irregular, and short-lived. It has been established
Annulate_lamella
Largest structure in the nucleus of eukaryotic cells
sequence lies outside the NOR and is transcribed by RNA Pol III in the nucleoplasm, after which it finds its way into the nucleolus to participate in the
Nucleolus
Openings in nuclear envelope of eukaryotic cells
The pores enable the nuclear transport of macromolecules between the nucleoplasm of the nucleus and the cytoplasm of the cell. Small molecules can easily
Nuclear_pore_complex
Topics referred to by the same term
whey, the liquid remaining after milk has been curdled and strained Nucleoplasm, a highly viscous liquid that surrounds the chromosomes and nucleoli
Plasma
Protein complex for mRNA transcription
synthesized rRNA in the nucleolus, and one which synthesized other RNA in the nucleoplasm, part of the nucleus but outside the nucleolus. In 1969, biochemists
RNA_polymerase_II
Biological process
prokaryotic cells, in eukaryotes, facilitated diffusion occurs in the nucleoplasm on chromatin filaments, accounted for by the switching dynamics of a
Facilitated_diffusion
Genetic disorder
2 s {\displaystyle {\tfrac {\mathrm {\mu m} ^{2}}{\mathrm {s} }}} in nucleoplasm and 0.13 μ m 2 s {\displaystyle \textstyle {\tfrac {\mathrm {\mu m} ^{2}}{\mathrm
Bloom_syndrome
Polish-German botanist (1844–1912)
the division of other nuclei." and originated the terms cytoplasm and nucleoplasm. Together with Walther Flemming and Edouard van Beneden, he elucidated
Eduard_Strasburger
Conceptual divisions of a living body
magnesium and sulfate ions. In the cell nucleus, the fluid component of the nucleoplasm is called the nucleosol. The interstitial, intravascular and transcellular
Fluid_compartments
Fibrillar network
similar in structure to the nuclear matrix, that extends throughout the nucleoplasm. The nuclear lamina consists of two components, lamins and nuclear lamin-associated
Nuclear_lamina
Family of proteins that form the nuclear pore complex
From the cytoplasm to the nucleoplasm, the three layers of the ring complex is named the cytoplasm, inner pore, and nucleoplasm rings respectively. Different
Nucleoporin
Proteins involved in nucleocytoplasmic transport
eukaryotic cell. (The inside of the nucleus is called the karyoplasm (or nucleoplasm). Generally, karyopherin-mediated transport occurs through nuclear pores
Karyopherin
apparatus, endoplasmic reticulum (ER), peroxisome, vacuoles, cytoskeleton, nucleoplasm, nucleolus, nuclear matrix and ribosomes. Bacteria also have subcellular
Subcellular_localization
Nuclear membrane surrounding the nucleus in eukaryotic cells
membrane to form nuclear pores. The inner nuclear membrane encloses the nucleoplasm, and is covered by the nuclear lamina, a mesh of intermediate filaments
Nuclear_envelope
Protein-coding gene in the species Homo sapiens
C-terminal domain binding P-TEFb complex binding Cellular component nucleoplasm chromosome condensed nuclear chromosome nucleus cytosol Biological process
BRD4
Protein-coding gene in the species Homo sapiens
abundant core proteins of hnRNP complexes and it is localized to the nucleoplasm. This protein, along with other hnRNP proteins, is exported from the
HNRNPA1
Type of amino acid sequence
connect at multiple sites, forming channels between the cytoplasm and the nucleoplasm. These channels are occupied by nuclear pore complexes (NPCs), complex
Nuclear_localization_sequence
Conversion of a gene's sequence into a mature gene product or products
they become part of functional RNP complex. This is done either in the nucleoplasm or in the specialized compartments called Cajal bodies. Their bases are
Gene_expression
Process of copying a segment of DNA into RNA
antibodies directed against polymerases. There are ≈10,000 factories in the nucleoplasm of a HeLa cell, among which are ≈8,000 polymerase II factories and ≈2
Transcription_(biology)
Protein found in humans
cardiolipin binding Cellular component cytoplasm inflammasome complex nucleoplasm NLRP3 inflammasome complex extracellular region extracellular space cytosol
GSDMD
German evolutionary biologist (1834–1914)
outstanding botanical physiologist of that century, coined the terms nucleoplasm and cytoplasm. He said "new cell nuclei can only arise from the division
August_Weismann
Protein-coding gene in the species Homo sapiens
Cellular component intracellular membrane-bounded organelle nucleus nucleoplasm cytoplasm replication fork protection complex Biological process cell
TIPIN
Protein-coding gene in the species Homo sapiens
transcription regulator complex Piccolo NuA4 histone acetyltransferase complex nucleoplasm nucleolus perinuclear region of cytoplasm nucleus Swr1 complex NuA4 histone
KAT5
Protein-coding gene in the species Homo sapiens
activity S-adenosyl-L-methionine binding Cellular component cytoplasm nucleoplasm methylosome nucleus cytosol Biological process positive regulation of
PRMT1
Protein-coding gene in humans
plasma membrane integral component of plasma membrane membrane nucleus nucleoplasm cytoplasm cytosol proteasome regulatory particle, lid subcomplex Biological
ADRM1
Protein-coding gene in the species Homo sapiens
cytoplasm PR-DUB complex intracellular anatomical structure nucleus nucleoplasm cytosol Biological process ubiquitin-dependent protein catabolic process
BAP1
Protein-coding gene in humans
single-stranded RNA binding Cellular component PcG protein complex nucleus nucleoplasm cytosol PRC1 complex Biological process regulation of transcription,
Chromobox_7
Protein-coding gene in the species Homo sapiens
membrane microtubule extracellular exosome extracellular space nucleus nucleoplasm cytosol Biological process substantia nigra development axonogenesis
2',3'-Cyclic-nucleotide 3'-phosphodiesterase
2',3'-Cyclic-nucleotide_3'-phosphodiesterase
latticework of protein polymers and microfilaments suspended in the nucleoplasm in the nuclei of eukaryotic cells, akin to the cytoskeleton in the cytoplasm
Glossary of cellular and molecular biology (M–Z)
Glossary_of_cellular_and_molecular_biology_(M–Z)
Protein found in humans
neuromuscular junction plasma membrane integral component of plasma membrane nucleoplasm extracellular region cell junction apicolateral plasma membrane basolateral
Coxsackievirus and adenovirus receptor
Coxsackievirus_and_adenovirus_receptor
Mammalian protein found in humans
TORC2 complex Golgi apparatus intracellular membrane-bounded organelle nucleoplasm soma PML body endoplasmic reticulum membrane Golgi membrane lysosomal
MTOR
Protein-coding gene in the species Homo sapiens
Ingelfinger D, et al. (2005). "Assembly and maturation of the U3 snoRNP in the nucleoplasm in a large dynamic multiprotein complex". Mol. Cell. 16 (5): 789–98.
NOP58
Experimental technique in cell biology
early by Axelrod et al. This could be due to flow of the cytoplasm or nucleoplasm, or transport along filaments in the cell such as microtubules by molecular
Fluorescence recovery after photobleaching
Fluorescence_recovery_after_photobleaching
Protein-coding gene in humans
component membrane ubiquitin ligase complex mediator complex nucleus nucleoplasm Biological process somitogenesis androgen receptor signaling pathway
MED12
Protein-coding gene in the species Homo sapiens
transcription activator activity, RNA polymerase II-specific Cellular component nucleoplasm cytosol nucleus Biological process cell cycle regulation of transcription
DMTF1
Mammalian protein found in humans
cytosol senescence-associated heterochromatin focus nucleus nuclear body nucleoplasm nucleolus mitochondrion protein-containing complex Biological process
P16
Gene and protein involved in Huntington's disease
shock protein binding Cellular component late endosome Golgi apparatus nucleoplasm autophagosome endoplasmic reticulum centriole cytoplasmic vesicle membrane
Huntingtin
Chromatin remodeling protein that is widely conserved across many eukaryotic organisms
histone binding Cellular component cytoplasm nucleus fibrillar center nucleoplasm Biological process regulation of transcription by RNA polymerase II chromatin
CHD1
Protein-coding gene in the species Homo sapiens
methyltransferase activity (H3-K36 specific) metal ion binding Cellular component nucleoplasm nucleus chromosome Biological process regulation of transcription, DNA-templated
SETD2
Organelles: Cytoplasm – Vacuole – Peroxisome – Plastid Cell nucleus Nucleoplasm – Nucleolus – Chromatin – Chromosome Endomembrane system Nuclear envelope
Outline_of_biology
Protein-coding gene in the species Homo sapiens
spliceosome membrane extracellular region spliceosomal complex nucleus nucleoplasm telomere Cajal body nuclear matrix extracellular exosome ribonucleoprotein
HNRNPA2B1
Protein-coding gene in the species Homo sapiens
cell leading edge cytoplasmic microtubule cell body neuron projection nucleoplasm cytoplasm protein-containing complex Biological process Hsp90 deacetylation
HDAC6
Nuclear protein inhibiting DNA replication
corepressor activity chromatin binding Cellular component cytoplasm nucleus nucleoplasm cytosol Biological process animal organ morphogenesis cell cycle negative
Geminin
Protein-coding gene in the species Homo sapiens
component Cajal body nuclear speck U4/U6 x U5 tri-snRNP complex U4atac snRNP nucleoplasm MLL1 complex U2-type spliceosomal complex precatalytic spliceosome spliceosomal
PRPF31
Mammalian protein found in Homo sapiens
binding chromatin binding Cellular component cytoplasm nuclear membrane nucleoplasm nucleus Biological process regulation of transcription by RNA polymerase
BRIP1
Protein-coding gene in the species Homo sapiens
nuclear import signal receptor activity Cellular component nuclear pore nucleoplasm dendrite nucleus cytoplasm cytosol host cell postsynaptic density glutamatergic
Importin_subunit_alpha-5
Human protein and coding gene
binding properties. The protein encoded by this gene is located in the nucleoplasm and has three repeats of KH domains that binds to RNAs. It is distinct
HNRNPK
Protein-coding gene in humans
functions. It is located in the nucleolus, but it can be translocated to the nucleoplasm in case of serum starvation or treatment with anticancer drugs. The protein
NPM1
Protein-coding gene in humans
actin filament binding Cellular component cytoplasm cytosol cytoskeleton nucleoplasm plasma membrane actin filament actin cortical patch Biological process
WIPF2
Protein-coding gene in the species Homo sapiens
Molecular function protein binding Cellular component nucleus cytoplasm nucleoplasm nucleolus nuclear pre-replicative complex Rix1 complex Biological process
WD_repeat_domain_18
Protein-coding gene in the species Homo sapiens
activity RNA binding cadherin binding zinc ion binding Cellular component nucleoplasm cytoplasm cytosol nuclear body intracellular anatomical structure Biological
TRIM25
Protein-coding gene in the species Homo sapiens
nucleus of most mammalian cells and is primarily distributed within the nucleoplasm, it can also be found concentrated within sub-nuclear domains known as
Non-POU domain-containing octamer-binding protein
Non-POU_domain-containing_octamer-binding_protein
Protein found in humans
insertion or deletion binding Cellular component MutSbeta complex membrane nucleoplasm nucleus mismatch repair complex Biological process cellular response
MSH3
Protein-coding gene in the species Homo sapiens
of cytoplasm ribosome transcription regulator complex nuclear speck nucleoplasm nucleolus endoplasmic reticulum Biological process DNA repair nucleic
APEX1
Protein-coding gene in the species Homo sapiens
component membrane plasma membrane nucleus cytoplasm extracellular space nucleoplasm cytosol Biological process social behavior positive regulation of ATP-dependent
DnaJ (Hsp40) homolog, subfamily C, member 9
DnaJ_(Hsp40)_homolog,_subfamily_C,_member_9
Mammalian protein found in Homo sapiens
binding Cellular component cytosol extracellular exosome cytoplasm nucleus nucleoplasm mitochondrion nuclear envelope protein-containing complex Biological
Glutathione_peroxidase_4
Protein-coding gene in the species Homo sapiens
activity Cellular component nonhomologous end joining complex nucleus nucleoplasm Golgi apparatus Biological process response to ionizing radiation DNA
Artemis_(protein)
Protein
double-stranded DNA binding Cellular component cytoplasm cytosol nuclear matrix nucleoplasm chromatin cleavage furrow nucleus histone methyltransferase complex endoplasmic
MEN1
inhibitor activity enzyme binding carbohydrate binding Cellular component nucleoplasm nucleus cytosol cytoplasm mitochondrion Biological process negative regulation
Glucokinase regulatory protein
Glucokinase_regulatory_protein
DNA topoisomerase enzyme
protection complex chromosome nuclear chromosome nucleus fibrillar center nucleoplasm nucleolus DNA topoisomerase type II (double strand cut, ATP-hydrolyzing)
TOP1
Protein-coding gene in the species Homo sapiens
arginine binding protein homodimerization activity Cellular component nucleoplasm nucleus cytosol cytoplasm protein-containing complex Biological process
PADI4
Protein embedded in inner membrane of nuclear envelope
All INM proteins are arranged such that their N-termini is facing the nucleoplasm and targeted by various kinases. They are synthesized in one of three
Inner nuclear membrane protein
Inner_nuclear_membrane_protein
Cellular process
particles, sometimes called pre-ribosomes, and takes place in the nucleolus, nucleoplasm, and cytoplasm. The yeast, S. cerevisiae is the eukaryotic model organism
Ribosome_biogenesis
Protein-coding gene in the species Homo sapiens
complex and the importin subunits dissociate. Importin alpha enters the nucleoplasm with its passenger protein and importin beta remains at the pore. The
Importin_subunit_alpha-7
Protein-coding gene in the species Homo sapiens
small-subunit processome membrane mitochondrion 90S preribosome t-UTP complex nucleoplasm fibrillar center nucleus nucleolus Biological process maturation of SSU-rRNA
HEATR1
Protein-coding gene in the species Homo sapiens
component histone methyltransferase complex nuclear speck nucleus chromosome nucleoplasm cytosol Set1C/COMPASS complex Biological process methylation regulation
SET_domain_containing_1B
Human gene and protein
isoelectric point of 4.9. The human FAM13B protein is localized in the nucleoplasm and contains multiple peroxisomal targeting signals and nuclear localization
FAM13B
Protein-coding gene in humans
cytosol senescence-associated heterochromatin focus nucleus nuclear body nucleoplasm nucleolus mitochondrion protein-containing complex Biological process
CDKN2A
Protein-coding gene in the species Homo sapiens
dioxygenase activity methylated histone binding Cellular component nucleus nucleoplasm cytosol chromosome Biological process regulation of transcription, DNA-templated
KDM8
Protein-coding gene in the species Homo sapiens
activity, RNA polymerase II-specific Cellular component cytoplasm nucleus nucleoplasm Biological process transcription, DNA-templated regulation of transcription
IRF2BP2
Protein-coding gene in the species Homo sapiens
activity Cellular component cytoplasm extracellular exosome nucleus nucleoplasm intracellular membrane-bounded organelle ciliary transition zone Biological
Cyclin dependent kinase like 1
Cyclin_dependent_kinase_like_1
Protein-coding gene in the species Homo sapiens
protein binding protein binding nucleosomal DNA binding Cellular component nucleoplasm nuclear chromosome nucleolus nucleus fibrillar center intracellular membrane-bounded
SMARCB1
Protein-coding gene in the species Homo sapiens
regulation, and protein-protein interactions. The protein localizes to the nucleoplasm and nucleoli, and interacts with p53. It modulates p53 function, and
IFI16
Protein-coding gene in the species Homo sapiens
polymerase II-specific Cellular component membrane nucleus fibrillar center nucleoplasm centrosome cytosol intracellular membrane-bounded organelle centriole
AKNA
Protein-coding gene in the species Homo sapiens
Cellular component chromosome chromosome, centromeric region nucleus nucleoplasm Biological process cell division cell cycle CENP-A containing chromatin
MIS18BP1
Protein-coding gene in the species Homo sapiens
cytosol intracellular anatomical structure perichromatin fibrils nucleus nucleoplasm Biological process regulation of apoptotic process regulation of transcription
TRIM24
Protein found in humans
telomere cap complex membrane transcription regulator complex chromosome nucleoplasm nonhomologous end joining complex nucleus Ku70:Ku80 complex cytoplasm
Ku70
Protein-coding gene in the species Homo sapiens
binding protein binding RNA binding Cellular component nucleus cytoplasm nucleoplasm nuclear speck Biological process termination of RNA polymerase II transcription
SFRS3
Protein-coding gene in the species Homo sapiens
ontology Molecular function protein binding Cellular component nucleus nucleoplasm extracellular space elongin complex Biological process transcription
ELOA
DNA-binding protein involved in methylation
extracellular space gamma-tubulin complex centrosome cytosol chromatin nucleoplasm Biological process negative regulation of neuron apoptotic process multicellular
MECP2
Protein-coding gene in the species Homo sapiens
ion binding thiol-dependent deubiquitinase Cellular component nucleus nucleoplasm cytoplasm Biological process cell cycle regulation of mitotic cell cycle
USP44
Protein-coding gene in the species Homo sapiens
N-glycosylase activity adenine/guanine mispair binding Cellular component nucleoplasm mitochondrion nucleus Biological process DNA repair metabolism depurination
MUTYH
Protein-coding gene in humans
predicated in an intracellular location and precisely localized to the nucleoplasm.[citation needed] CEBPB is capable of increasing the expression of several
CEBPB
Protein-coding gene in the species Homo sapiens
identical protein binding Cellular component cytoplasm cytoskeleton nucleoplasm microtubule organizing center Biological process cerebral cortex development
Microcephalin
Protein-coding gene in the species Homo sapiens
binding transferase activity Cellular component cytoplasm cytosol nucleus nucleoplasm cell junction Biological process cell population proliferation peptidyl-diphthamide
DPH1
Protein-coding gene in the species Homo sapiens
binding cation binding Cellular component cytoplasm membrane nucleus nucleoplasm Biological process protein dephosphorylation peptidyl-threonine dephosphorylation
PPM1G
Protein-coding gene in the species Homo sapiens
Cellular component nuclear membrane nuclear envelope membrane nuclear pore nucleoplasm nucleus cytosol host cell Biological process mRNA transport viral transcription
NUPL2
Protein-coding gene in the species Homo sapiens
exchange factor activity Cellular component cytoplasm mitochondrion nucleoplasm nuclear body cytoplasmic vesicle membrane membrane cytoplasmic vesicle
SH3BP5
Protein that in humans is encoded by the WTAP gene
protein. Like WT1 protein, this protein is localized throughout the nucleoplasm as well as in speckles and partially colocalizes with splicing factors
WTAP_(gene)
Protein-coding gene in the species Homo sapiens
the binding of U2 snRNP to pre-mRNAs. This protein is localized in the nucleoplasm and it is also detected in the perinucleolar structure. Alternatively
PTBP1
Protein-coding gene in the species Homo sapiens
binding retinal binding all-trans-retinol binding Cellular component nucleoplasm cytoplasm cytosol lipid droplet Biological process retinoic acid biosynthetic
RBP1
Protein-coding gene in the species Homo sapiens
DNA binding protein binding Cellular component cytoplasm centrosome nucleoplasm microtubule organizing center cell cortex cytoskeleton nucleus fibrillar
STOX1
Protein-coding gene in the species Homo sapiens
L is present in the nucleoplasm as part of the HNRP complex. HNRP proteins have also been identified outside of the nucleoplasm. Exchange of hnRNP for
HNRNPL
Protein-coding gene in the species Homo sapiens
mRNA 3'-UTR binding nucleic acid binding RNA binding Cellular component nucleoplasm Biological process regulation of transcription, DNA-templated mRNA splicing
ELAV-like_protein_2
serine/threonine kinase activity Cellular component cytoplasm mitochondrion nucleus nucleoplasm synapse Biological process locomotory behavior phosphorylation negative
PAK5
Protein-coding gene in humans
Cellular component cytoplasm cytoplasmic stress granule nucleolus nucleus nucleoplasm spliceosomal complex ribonucleoprotein complex Biological process stress
CIRBP
NUCLEOPLASM
NUCLEOPLASM
NUCLEOPLASM
NUCLEOPLASM
Boy/Male
Hindu, Indian, Tamil
Gods Name; Lord Vishnu
Girl/Female
Tamil
Padmakalyani | பதà¯à®®à®¾à®‚கலà¯à®¯à®¾à®¨à¯€
Name of a Raga
Boy/Male
Bengali, Hindu, Indian, Telugu, Traditional
Lord of All Gods / Ganas
Girl/Female
Australian, Christian, Polish
World Ruler
Girl/Female
Arabic, Muslim, Saudi, Syrian, Yemeni
Beautiful; Intelligent; Generous; Noble; Diminutive of Nasiba
Girl/Female
Hindu, Indian, Sanskrit, Tamil
Beautiful Mind
Boy/Male
Christian, Indian
Fearless
Boy/Male
African, Australian, Danish, French, German, Japanese, Nigerian, Portuguese, Teutonic
Power of the Wolf; Second Son of the Family; Peace
Boy/Male
Hindu, Indian, Traditional
A Sage and Friend of Pandavas
Girl/Female
Tamil
Srimathi | à®·à¯à®°à¯€à®®à®¤à¯€
Goddess Lakshmi, Fortunate, Respected
NUCLEOPLASM
NUCLEOPLASM
NUCLEOPLASM
NUCLEOPLASM
NUCLEOPLASM
n.
The matter composing the nucleus of a cell; the protoplasm of the nucleus; karyoplasma.
a.
Of or pertaining to nucleoplasm; -- esp. applied to a body formed in the developing ovum from the plasma of the nucleus of the germinal vesicle.
n.
The protoplasmic substance of the nucleus of a cell: nucleoplasm; -- in opposition to kytoplasma, the protoplasm of the cell.
n.
A body, usually spheroidal, in a cell or a protozoan, distinguished from the surrounding protoplasm by a difference in refrangibility and in behavior towards chemical reagents. It is more or less protoplasmic, and consists of a clear fluid (achromatin) through which extends a network of fibers (chromatin) in which may be suspended a second rounded body, the nucleolus (see Nucleoplasm). See Cell division, under Division.