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Protein-coding gene in the species Homo sapiens
Interferon lambda receptor 1 is a subunit for the interferon lambda receptor encoded by the IFNLR1 gene. It was formerly known as interleukin 28 receptor
Interferon_lambda_receptor_1
Protein-coding gene in the species Homo sapiens
that consists of interleukin 10 receptor, beta (IL10RB) and interferon lambda receptor 1 (IFNLR1) to signal via the JAK-STAT anti-viral pathway. [provided
Interferon_lambda_3
Type II cytokine receptor
Interferon-lambda receptor (IFNLR), formerly known as the interleukin-28 receptor (IL28R), is a type II cytokine receptor found largely in epithelial
Interferon-lambda_receptor
Group of anti-viral cytokines
The type III interferon group is a group of anti-viral cytokines that in humans consists of a singular family, IFN-λ (lambda). Their function is similar
Interferon_type_III
Protein-coding gene in the species Homo sapiens
Interferon lambda 4 (gene symbol: IFNL4) is one of the most recently discovered human genes and the newest addition to the interferon lambda protein family
Interferon_lambda_4
Signaling proteins released by host cells in response to the presence of pathogens
induction of Th1 immune response. Interferon type III IFN type III signals through the interferon-lambda receptor (IFNLR) consisting of IL10R2 (also
Interferon
Protein-coding gene in the species Homo sapiens
two chains of a receptor for type I interferons, including interferon-alpha, -beta, and -lambda. Binding and activation of the receptor stimulates Janus
IFNAR1
Pharmaceutical drug
shown that genetic polymorphisms near the human IL28B gene, encoding interferon lambda 3, are associated with significant differences in response to the
Peginterferon_alfa-2b
Sendai virus, virus of rodents
paramyxovirus C proteins: inhibition of Toll-like receptor 7/9-dependent alpha interferon induction". FEBS Letters. 588 (1): 28–34. Bibcode:2014FEBSL.588...28Y. doi:10
Murine_respirovirus
Pharmaceutical drug
shown that genetic polymorphisms near the human IL28B gene, encoding interferon lambda 3, are associated with significant differences in response to the
Peginterferon_alfa-2a
Protein-coding gene in the species Homo sapiens
Interferon alpha-1 is a protein that in humans is encoded by the IFNA1 gene. Leukocyte interferon is produced predominantly by B lymphocytes. Immune interferon
Interferon_alpha-1
Protein-coding gene in the species Homo sapiens
transduction. This gene and three other interferon receptor genes, IFNAR2, IFNAR1, and IFNGR2, form a class II cytokine receptor gene cluster located in a small
Interleukin 10 receptor, beta subunit
Interleukin_10_receptor,_beta_subunit
Anti-inflammatory cytokine
(Mda-7), IL-26 and interferons type-I (IFN-alpha, -beta, -epsilon, -kappa, -omega), type-II (IFN-gamma) and type-III (IFN-lambda, including IL-28A, IL-28B
Interleukin_10
Protein-coding gene in the species Homo sapiens
signaling pathways as type I interferons. IL-29 receptor signals through JAK-STAT pathways leading to activated expression of interferon-stimulated genes and
Interleukin_29
Artificial stimulation of the immune system to treat cancer
S2CID 223082. Lasfar A, Abushahba W, Balan M, Cohen-Solal KA (2011). "Interferon lambda: a new sword in cancer immunotherapy". Clinical & Developmental Immunology
Cancer_immunotherapy
Belgian molecular biologist and entrepreneur (1947–1992)
hirudin, α-1-antitrypsin, gamma-interferon and interleukins, and variants thereof, construction of virtually all recombinant proteins of HIV-1, HIV-2 and
Jean-Pierre_Lecocq
Protein-coding gene in Homo sapiens
Lim JT, Schreiber RD, et al. (March 1996). "Phosphorylated interferon-alpha receptor 1 subunit (IFNaR1) acts as a docking site for the latent form of
STAT2
Human infectious disease
are currently under development include pegylated interferon lambda (λ), which binds to receptors on the hepatocyte surface leading to an intracellular
Hepatitis_D
Interleukin-10 receptor subunit alpha precursor - Homo sapiens (Human)". www.uniprot.org. Retrieved 2015-10-13. "IL10RB - Interleukin-10 receptor subunit beta
List of human clusters of differentiation
List_of_human_clusters_of_differentiation
Russian medical geneticist
Interferon Lambda 4 Is Associated with Reduced Proliferation and Increased Cell Death in Human Hepatic Cells” published in the Journal of Interferon &
Ludmila_Prokunina-Olsson
RNA family
cell, HepG2 cells expressing miR-122) mount an effective antiviral interferon-lambda (IFNλ) based innate immune response to hepatitis C virus (HCV) infection
MiR-122
Contagious disease caused by SARS-CoV-2
IM, Miao VN, Tzouanas CN, et al. (28 May 2020). "SARS-CoV-2 Receptor ACE2 Is an Interferon-Stimulated Gene in Human Airway Epithelial Cells and Is Detected
COVID-19
Group of disorders
excessive release of these cytokines (e.g. tumor necrosis factor-α, interferon-γ, Interleukin 1 beta, interleukin 18, and CXCL9) causes a systemic and often
Epstein–Barr virus–associated lymphoproliferative diseases
Epstein–Barr_virus–associated_lymphoproliferative_diseases
Protein-coding gene in humans
"Assignment of the genes encoding human interleukin-8 receptor types 1 and 2 and an interleukin-8 receptor pseudogene to chromosome 2q35". Genomics. 14 (3):
CXCL7
440.890 – interferon type i MeSH D12.776.467.374.440.890.125 – interferon type i, recombinant MeSH D12.776.467.374.440.890.125.100 – interferon alfa-2a
List_of_MeSH_codes_(D12.776)
Variant of SARS-CoV-2, the virus that causes COVID-19
complex I (MHC-I) degradation", and that "SARS-CoV-2 ORF8 suppresses type I interferon (IFN)–mediated antiviral response". Referring to amino-acid position 501
SARS-CoV-2_Alpha_variant
Protein that regulates the rate of DNA transcription
Heat Shock Factors 3.4.1 Family: HSF 3.5 Class: Tryptophan clusters 3.5.1 Family: Myb 3.5.2 Family: Ets-type 3.5.3 Family: Interferon regulatory factors 3
Transcription_factor
Preventative and therapeutic medications for COVID-19 infection
categories, such as anti-inflammatory, antimalarial, interferon, protein-based, antibiotics, and receptor-modulating compounds. Pivotal Phase III trials assess
COVID-19_drug_development
Protein-coding gene in the species Homo sapiens
transcription factor 1 is a protein that in humans is encoded by the POU2F1 gene. POU2F1 has been shown to interact with: EPRS, Glucocorticoid receptor, Glyceraldehyde
POU2F1
Study of genetic variants in different individuals
GWA study has shown that SNPs near the human IL28B gene, encoding interferon lambda 3, are associated with significant differences in response to the
Genome-wide_association_study
Organism altered by genetic engineering
hemophilia, human growth hormone to treat various forms of dwarfism, interferon to treat some cancers, erythropoietin for anemic patients, and tissue
Genetically_modified_organism
DNA pattern affecting anatomy development
and structural similarity to prokaryotic transcription factors, such as lambda phage proteins that alter the expression of genes in prokaryotes. The HTH
Homeobox
Vaccine against COVID-19
of the N protein. A robust increase of T helper cells (CD4+) secreting interferon gamma was detected 14 days after both doses in response to stimulation
CoronaVac
Structural motif capable of binding DNA
several genes encoding transcription regulatory proteins from bacteriophage lambda and Escherichia coli: Cro, CAP, and λ repressor, which were found to share
Helix-turn-helix
Complete set of molecular interactions in a biological cell
bacteriophage lambda Escherichia coli bacteriophage T7 Streptococcus pneumoniae bacteriophage Dp-1 Streptococcus pneumoniae bacteriophage Cp-1 The lambda and VZV
Interactome
Protein family
structure of the Oct-1 POU-specific domain reveals a striking similarity to the bacteriophage lambda repressor DNA-binding domain". Cell. 73 (1): 193–205. doi:10
POU_domain
Drug repurposing research related to COVID-19
activator receptor) of at least 6 ng per ml." Drugs with immune modulating effects that may prove useful in COVID-19 treatment include type I Interferons such
COVID-19 drug repurposing research
COVID-19_drug_repurposing_research
Protein-coding gene in the species Homo sapiens
S2CID 18269284. Santi E, Capone S, Mennuni C, et al. (2000). "Bacteriophage lambda display of complex cDNA libraries: a new approach to functional genomics"
EMX1
Overview of the events of 2023 in science
therapeutic candidates are reported: a phase 3 trialed pegylated interferon lambda against COVID-19 (and other viruses) (9 Feb), a monkey-tested potential
January–March_2023_in_science
Variant of a biopharmaceutical
of approved recombinant drugs (e.g., insulin, human growth hormone, interferons, erythropoietin, monoclonal antibodies and more) any other biotech company
Biosimilar
INTERFERON LAMBDA-RECEPTOR-1
INTERFERON LAMBDA-RECEPTOR-1
Boy/Male
Gujarati, Hindu, Indian, Kannada, Malayalam, Marathi, Sanskrit, Telugu
Preceptor of the World
Female
Native American
Native American Indian name ALAMEDA means "grove of cottonwood."
Girl/Female
Indian
Flame
Surname or Lastname
English
English : from Middle English lamb, a nickname for a meek and inoffensive person, or a metonymic occupational name for a keeper of lambs. See also Lamm.English : from a short form of the personal name Lambert.Irish : reduced Anglicized form of Gaelic Ó Luain (see Lane 3). MacLysaght comments: ‘The form Lamb(e), which results from a more than usually absurd pseudo-translation (uan ‘lamb’), is now much more numerous than O’Loan itself.’Possibly also a translation of French agneau.
Girl/Female
Arabic, Indian, Muslim, Pashtun, Sanskrit
Flame; Large; Spacious; Tall; Another Name for Durga and Lakshmi
Girl/Female
Muslim
Flame
Boy/Male
Hindu
Preceptor of the universe
Boy/Male
Tamil
Sarvacharya | ஸரà¯à®µà®¾à®šà®¾à®°à¯à®¯
Preceptor of all
Sarvacharya | ஸரà¯à®µà®¾à®šà®¾à®°à¯à®¯
Boy/Male
Hindu
Preceptor of Skanda
Surname or Lastname
English
English : habitational name from Lambden in Berwickshire.
Boy/Male
Indian, Sanskrit
The Preceptor
Boy/Male
Hindu
Preceptor of all
Boy/Male
Arabic
Educator; Preceptor
Boy/Male
Tamil
Skandaguru | ஸà¯à®•à¯à®¨à¯à®¤à®•à¯à®°à¯à®‚
Preceptor of Skanda
Skandaguru | ஸà¯à®•à¯à®¨à¯à®¤à®•à¯à®°à¯à®‚
Surname or Lastname
English
English : from a pet form of Lamb 1 and 2.English : from an Old Norse personal name Lambi, from lamb ‘lamb’.
Female
Spanish
Feminine form of Spanish Amado, AMADA means "beloved."
Female
Italian
Italian form of English Amber, AMBRA means "amber."
Female
Greek
(Λαμία) Greek myth name of an evil spirit who abducts and devours children, LAMIA means "large shark." The name means "vampire" in Latin and "fiend" in Arabic.
Boy/Male
Tamil
Jagatguru | ஜகதகà¯à®°à¯
Preceptor of the world
Jagatguru | ஜகதகà¯à®°à¯
Boy/Male
Tamil
Jagadguru | ஜகதகà¯à®°à¯
Preceptor of the universe
INTERFERON LAMBDA-RECEPTOR-1
INTERFERON LAMBDA-RECEPTOR-1
Boy/Male
Hindu
Shailastha resident of Gandhamadhana
Boy/Male
Hindu
Tej i am
Male
Egyptian
, Apophis.
Boy/Male
Teutonic American German
Famous wolf.
Girl/Female
Tamil
Swetharani | ஸà¯à®µà¯‡à®¤à®°à®¾à®¨à¯€
Fair complexioned, Pure
Boy/Male
Indian, Modern
Anti Soft
Boy/Male
Indian
Young fox, Sehabie Rasool sawas
Boy/Male
Arabic
Imposter; Big Liar
Girl/Female
Afghan, Anglo, British, Danish, English, German, Swedish, Welsh
Holy; Blessed Reconciliation; Joy; Peace; Holy Peacemaking
Boy/Male
Indian
Protector
INTERFERON LAMBDA-RECEPTOR-1
INTERFERON LAMBDA-RECEPTOR-1
INTERFERON LAMBDA-RECEPTOR-1
INTERFERON LAMBDA-RECEPTOR-1
INTERFERON LAMBDA-RECEPTOR-1
v. i.
To clash or interfere.
n.
The act of improperly interfering.
n.
The act or manner of receiving, esp. of receiving visitors; entertainment; hence, an occasion or ceremony of receiving guests; as, a hearty reception; an elaborate reception.
imp. & p. p.
of Lamb
n.
The chief elective officer of some universities, as in France and Scotland; sometimes, the head of a college; as, the Rector of Exeter College, or of Lincoln College, at Oxford.
n.
The head of a preceptory among the Knights Templars.
n.
The name of the Greek letter /, /, corresponding with the English letter L, l.
v. i.
To come in collision; to be in opposition; to clash; as, interfering claims, or commands.
v. i.
To interfere; to intermeddle.
p. pr. & vb. n.
of Interfere
v. i.
To strike one foot against the opposite foot or ankle in using the legs; -- sometimes said of a human being, but usually of a horse; as, the horse interferes.
n.
One who gives commands, or makes rules; specifically, the master or principal of a school; a teacher; an instructor.
v. i.
To bring forth a lamb or lambs, as sheep.
n.
A viola da gamba.
n.
Any person who is as innocent or gentle as a lamb.
n.
A bruise or abrasion produced on the foot or ankle of a horse that interferes. See Interfere, 3.
imp. & p. p.
of Interfere
n.
The act of receiving; receipt; admission; as, the reception of food into the stomach; the reception of a letter; the reception of sensation or ideas; reception of evidence.
n.
The point of junction of the sagittal and lambdoid sutures of the skull.
n.
One who interferes.