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EXOSOME COMPLEX

  • Exosome complex
  • Protein complex that degrades RNA

    The exosome complex (or PM/Scl complex, often just called the exosome) is a multi-protein intracellular complex capable of degrading various types of

    Exosome complex

    Exosome complex

    Exosome_complex

  • Exosome
  • Topics referred to by the same term

    Exosome may refer to: Exosome complex, an intracellular macromolecular protein complex involved in RNA degradation Exosome (vesicle), an extracellular

    Exosome

    Exosome

  • TRAMP complex
  • Multiprotein and heterotrimeric complex

    , Vanacova et al. and Wyers et al. in 2005. It interacts with the exosome complex in the nucleus of eukaryotic cells and is involved in the 3' end processing

    TRAMP complex

    TRAMP complex

    TRAMP_complex

  • DIS3
  • Protein-coding gene in the species Homo sapiens

    Exosome complex exonuclease RRP44 or Dis3 is an enzyme that in humans is encoded by the DIS3 gene. Its protein product is an RNase enzyme homologous to

    DIS3

    DIS3

    DIS3

  • Exosome component 9
  • Protein-coding gene in the species Homo sapiens

    Exosome component 9, also known as EXOSC9, is a human gene, the protein product of which (sometimes called RRP45 or PM/Scl-75) is part of the exosome

    Exosome component 9

    Exosome component 9

    Exosome_component_9

  • Exosome component 3
  • Protein-coding gene in the species Homo sapiens

    Exosome component 3, also known as EXOSC3, is a human gene, which is part of the exosome complex. Mutations in EXOSC3 cause pontocerebellar hypoplasia

    Exosome component 3

    Exosome component 3

    Exosome_component_3

  • Exosome component 4
  • Protein-coding gene in the species Homo sapiens

    Exosome component 4, also known as EXOSC4, is a human gene, which is part of the exosome complex. Exosome component 4 has been shown to interact with

    Exosome component 4

    Exosome component 4

    Exosome_component_4

  • Exosome component 8
  • Protein-coding gene in the species Homo sapiens

    Exosome component 8, also known as EXOSC8, is a human gene, the protein product of which is part of the exosome complex. Exosome component 8 has been shown

    Exosome component 8

    Exosome component 8

    Exosome_component_8

  • Exosome (vesicle)
  • Membrane-bound extracellular vesicles

    Exosomes, ranging in size from 30 to 150 nanometers, are membrane-bound extracellular vesicles (EVs) that are produced in the endosomal compartment of

    Exosome (vesicle)

    Exosome (vesicle)

    Exosome_(vesicle)

  • Messenger RNA
  • RNA that is read by the ribosome to produce a protein

    destabilize the cap binding complex. The message is then subject to degradation by either the exosome complex or the decapping complex. In this way, translationally

    Messenger RNA

    Messenger RNA

    Messenger_RNA

  • Ski complex
  • arm and the Ski2 insertion domain. In yeast, the complex guides RNA molecules to the exosome complex for degradation via a fourth protein, called Ski7

    Ski complex

    Ski_complex

  • Exosome component 7
  • Protein-coding gene in the species Homo sapiens

    Exosome component 7, also known as EXOSC7, is a human gene, the protein product of which is part of the exosome complex. Exosome component 7 has been shown

    Exosome component 7

    Exosome component 7

    Exosome_component_7

  • Complex
  • Topics referred to by the same term

    2022 Complex Networks, publisher of the now-only-online magazine Complex Protein–ligand complex, a complex of a protein bound with a ligand Exosome complex

    Complex

    Complex

  • Exosome component 10
  • Protein-coding gene in the species Homo sapiens

    Exosome component 10, also known as EXOSC10, is a human gene, the protein product of which (sometimes called PM/Scl-100) is part of the exosome complex

    Exosome component 10

    Exosome component 10

    Exosome_component_10

  • Chordate
  • Phylum of animals having a dorsal nerve cord

    also strongly supported by two CSIs found in the proteins predicted exosome complex RRP44 and serine palmitoyltransferase, that are exclusively shared

    Chordate

    Chordate

    Chordate

  • Vertebrate
  • Subphylum of chordates

    by two molecular markers, the proteins Rrp44 (associated with the exosome complex) and serine C-palmitoyltransferase. These are exclusively shared by

    Vertebrate

    Vertebrate

    Vertebrate

  • Exosome component 6
  • Protein-coding gene in the species Homo sapiens

    Exosome complex exonuclease MTR3 is an enzyme that in humans is encoded by the EXOSC6 gene. This gene product constitutes one of the subunits of the multisubunit

    Exosome component 6

    Exosome component 6

    Exosome_component_6

  • Non-stop decay
  • have reached the far 3' end of an mRNA and guides the mRNA to the exosome complex, or to RNase R in bacteria for selective degradation. In contrast to

    Non-stop decay

    Non-stop decay

    Non-stop_decay

  • Exos
  • Topics referred to by the same term

    exos means powered exoskeletons In medicine, exos is short for the exosome complex Lotus Exos, see Lotus Cars "EXOS", a 2016 song by Blank Banshee from

    Exos

    Exos

  • Polynucleotide phosphorylase
  • Class of enzymes

    and archaea, a structurally and evolutionary related complex exists, called the exosome complex. The same abbreviation (PNPase) is also used for another

    Polynucleotide phosphorylase

    Polynucleotide phosphorylase

    Polynucleotide_phosphorylase

  • DIS3L
  • Protein-coding gene in the species Homo sapiens

    enzyme homologous to the yeast protein Rrp44, and can be part of the exosome complex in the cytoplasm of eukaryotic cells. GRCh38: Ensembl release 89: ENSG00000166938

    DIS3L

    DIS3L

    DIS3L

  • Exoribonuclease
  • Class of enzymes that degrade RNA

    (such as RNase D or RNase PH) but also can be complexes of multiple proteins, such as the exosome complex (in which four of the major exoribonuclease families

    Exoribonuclease

    Exoribonuclease

    Exoribonuclease

  • Antinuclear antibody
  • Autoantibody that binds to contents of the cell nucleus

    antibodies are components of the RNA-processing exosome complex in the nucleolus. There are ten proteins in this complex and antibodies to eight of them are found

    Antinuclear antibody

    Antinuclear antibody

    Antinuclear_antibody

  • Exonuclease
  • Class of enzymes; type of nuclease

    the main routes of RNA degradation is performed by the multi-protein exosome complex, which consists largely of 3′ to 5′ exoribonucleases. RNA polymerase

    Exonuclease

    Exonuclease

    Exonuclease

  • Proteasome
  • Protein complexes which degrade ubiquitin-tagged proteins by proteolysis

    biomarkers. Biology portal The Proteolysis Map DSS1/SEM1 protein family Exosome complex Endoplasmic-reticulum-associated protein degradation JUNQ and IPOD

    Proteasome

    Proteasome

    Proteasome

  • Autoantibody
  • Antibody directed against an autogenic protein

    (1998). "Autoantibodies against a 210 kDa glycoprotein of the nuclear pore complex as a prognostic marker in patients with primary biliary cirrhosis". J.

    Autoantibody

    Autoantibody

  • Exosome component 5
  • Protein-coding gene in the species Homo sapiens

    Exosome component 5, also known as EXOSC5, is a human gene, which is part of the exosome complex. Biallelic pathogenic variation in EXOSC5 causes autosomal

    Exosome component 5

    Exosome component 5

    Exosome_component_5

  • Exosome component 1
  • Protein-coding gene in the species Homo sapiens

    EXOSC1 gene. This gene encodes a core component of the exosome complex. The mammalian exosome is required for rapid degradation of AU rich element-containing

    Exosome component 1

    Exosome component 1

    Exosome_component_1

  • MRNA surveillance
  • Intracellular mechanisms

    recognition by the cytosolic exosome. The Ski7-exosome complex rapidly deadenylates the mRNA molecule which allows the exosome to decay the transcript in

    MRNA surveillance

    MRNA_surveillance

  • RNase PH
  • Type of enzyme

    domain (RPD). Two highly related exoribonuclease complexes: Polynucleotide phosphorylase Exosome complex Ishii R, Nureki O, Yokoyama S (August 2003). "Crystal

    RNase PH

    RNase PH

    RNase_PH

  • SKIV2L
  • Protein-coding gene in the species Homo sapiens

    damaged material. The RNA exosome multiprotein complex performs this function and is dependent on cofactors.  The exosome was initially discovered in

    SKIV2L

    SKIV2L

    SKIV2L

  • Degradosome
  • degradation pathway could be an exclusive trait of eukaryotic cells. Exosome complex Proteasome Carpousis AJ (April 2002). "The Escherichia coli RNA degradosome:

    Degradosome

    Degradosome

  • Glossary of cellular and molecular biology (0–L)
  • than in the middle, as with endonucleases). exosome 1.  (protein complex) An intracellular multi-protein complex which serves the function of degrading various

    Glossary of cellular and molecular biology (0–L)

    Glossary_of_cellular_and_molecular_biology_(0–L)

  • Cryptic unstable transcript
  • due to the combined activity of poly-adenylating polymerases and exosome complexes. CUT transcription occurs through RNA Polymerase II and initiates

    Cryptic unstable transcript

    Cryptic_unstable_transcript

  • DIS3L2
  • Protein-coding gene in the species Homo sapiens

    3'/5' exonucleolytic subunits of the RNA exosome. The exosome is a large multimeric ribonucleotide complex responsible for degrading various RNA substrates

    DIS3L2

    DIS3L2

    DIS3L2

  • Index of molecular biology articles
  • evolutionary clock - evolutionary footprinting - exon - exonuclease - exosome complex - expression - expression clone - expression vector - extended ELM2

    Index of molecular biology articles

    Index_of_molecular_biology_articles

  • T-complex 1
  • Protein-coding gene in the species Homo sapiens

    T-complex protein 1 or T-complex protein 1 subunit alpha, abbreviated TCP1 or TCP-1, is a protein that in humans is encoded by the TCP1 gene. This protein

    T-complex 1

    T-complex 1

    T-complex_1

  • Jessica Borger
  • Australian T Cell immunologist

    Caveolin-1 in T cell cholesterol homeostasis, integrin signaling and exosome complex biogenesis. In 2016, Borger took a position in the Central Clinical

    Jessica Borger

    Jessica Borger

    Jessica_Borger

  • RNA-induced silencing complex
  • Multiprotein complex

    P-bodies. 3'-to-5' degradation of the transcript is conducted by the exosome and Ski complex. RISC can modulate the loading of ribosome and accessory factors

    RNA-induced silencing complex

    RNA-induced_silencing_complex

  • Translational Genomics Research Institute
  • Research institute

    traumatic encephalopathy (CTE) in former NFL players in partnership with Exosome Sciences. "Administrative leadership". Tgen. Retrieved April 8, 2024. Alltucker

    Translational Genomics Research Institute

    Translational Genomics Research Institute

    Translational_Genomics_Research_Institute

  • Polyadenylation
  • Addition of adenylic acids to 3' end of mature mRNA

    by the TRAMP complex, which maintains a tail that is around four nucleotides long on the 3′ end. The RNA is then degraded by the exosome. Poly(A) tails

    Polyadenylation

    Polyadenylation

  • Exosome component 2
  • Protein-coding gene in the species Homo sapiens

    Exosome component 2, also known as EXOSC2, is a protein which in humans is encoded by the EXOSC2 gene. Mammalian mRNAs contain AU-rich elements (AREs)

    Exosome component 2

    Exosome component 2

    Exosome_component_2

  • ATP5F1A
  • Protein-coding gene in the species Homo sapiens

    phosphorylation. ATP synthase is composed of two linked multi-subunit complexes: the soluble catalytic core, F1, and the membrane-spanning component,

    ATP5F1A

    ATP5F1A

    ATP5F1A

  • Scleromyositis
  • Autoimmune disease

    Autoantibodies often found in these patients are the anti-PM/Scl (anti-exosome) antibodies. The symptoms that are seen most often are typical symptoms

    Scleromyositis

    Scleromyositis

  • TSG101
  • Protein-coding gene in the species Homo sapiens

    protein domain of the VPS23/TSG101 subunit. The assembly of the ESCRT-I complex is directed by the C-terminal steadiness box (SB) of VPS23, the N-terminal

    TSG101

    TSG101

    TSG101

  • Microvesicle
  • Type of extracellular vesicle

    to be larger, on average, than intracellularly-generated EVs known as exosomes. Microvesicles play a role in intercellular communication and can transport

    Microvesicle

    Microvesicle

    Microvesicle

  • PSMB8
  • Protein found in humans

    The resulting proteasome complex becomes the so-called immunoproteasome. An essential function of the modified proteasome complex, the immunoproteasome,

    PSMB8

    PSMB8

    PSMB8

  • VPS35
  • Protein-coding gene in the species Homo sapiens

    Parkinson's disease (PD) and Alzheimer's disease (AD). VPS35 is part of a complex called the retromer, which is responsible for transporting select cargo

    VPS35

    VPS35

    VPS35

  • Plasmin
  • Enzyme in human blood that degrades clots and other proteins

    collapses about the plasmin. In the resulting α2-macroglobulin-plasmin complex, the active site of plasmin is sterically shielded, thus substantially

    Plasmin

    Plasmin

    Plasmin

  • Metastasis
  • Spreading of a disease inside a body

    experiments suggests that the co-option of intercellular cross-talk mediated by exosome vesicles is a critical factor involved in all steps of the invasion-metastasis

    Metastasis

    Metastasis

    Metastasis

  • Extracellular vesicle
  • Vesicles found outside cells

    200 nm. EVs can be divided according to size and synthesis route into exosomes, microvesicles and apoptotic bodies. The composition of EVs varies depending

    Extracellular vesicle

    Extracellular_vesicle

  • CD9
  • Human protein-encoding gene

    role in many cellular processes including exosome biogenesis. CD9 is commonly used as a marker for exosomes as it is contained on their surface. However

    CD9

    CD9

    CD9

  • Small interfering RNA
  • Biomolecule

    2005). "Decay of mRNAs Targeted by RISC Requires XRN1, the Ski Complex, and the Exosome". RNA. 11 (4): 459–69. doi:10.1261/rna.7231505. PMC 1370735. PMID 15703439

    Small interfering RNA

    Small interfering RNA

    Small_interfering_RNA

  • VPS37B subunit of ESCRT-I
  • Protein-coding gene in the species Homo sapiens

    membrane plasma membrane midbody endosome membrane extracellular exosome ESCRT I complex host cell intracellular membrane-bounded organelle Biological process

    VPS37B subunit of ESCRT-I

    VPS37B subunit of ESCRT-I

    VPS37B_subunit_of_ESCRT-I

  • ATP6V0D2
  • Protein-coding gene in the species Homo sapiens

    ATPase complex endosome membrane extracellular exosome lysosomal membrane early endosome plasma membrane proton-transporting V-type ATPase complex Biological

    ATP6V0D2

    ATP6V0D2

    ATP6V0D2

  • CRYAB
  • Protein-coding gene in humans

    augmented αB-crystallin in tumor development induced by deficient TSC1/2 complex". Oncogene. 33 (34): 4352–4358. doi:10.1038/onc.2013.401. PMID 24077282

    CRYAB

    CRYAB

    CRYAB

  • Ribosome biogenesis
  • Cellular process

    Pre-ribosomes that build up in the nucleus are destroyed by the exosome, which is a multisubunit complex with exonuclease activity. If defective ribosomal subunits

    Ribosome biogenesis

    Ribosome biogenesis

    Ribosome_biogenesis

  • NEDD8
  • Protein found in the human body

    Their NEDDylation is critical for the recruitment of E2 to the ligase complex, thus facilitating ubiquitin conjugation. NEDD8 modification has therefore

    NEDD8

    NEDD8

    NEDD8

  • Drug delivery to the brain
  • Passing of drugs through the blood brain-barrier

    group from the University of Oxford led by Prof. Matthew Wood claims that exosomes can cross the blood–brain barrier and deliver siRNAs, antisense oligonucleotides

    Drug delivery to the brain

    Drug_delivery_to_the_brain

  • CHI3L1
  • Protein found in humans

    SK, Bhardwaj R, Wilczynska KM, Dumur CI, Kordula T (November 2011). "A complex of nuclear factor I-X3 and STAT3 regulates astrocyte and glioma migration

    CHI3L1

    CHI3L1

    CHI3L1

  • PSMA6
  • Protein found in humans

    beta2i, beta5i) that contributes to the complete assembly of 20S proteasome complex. The gene PMSA6 encodes a member of the peptidase T1A family, that is a

    PSMA6

    PSMA6

    PSMA6

  • ZFP36
  • Protein-coding gene in the species Homo sapiens

    production by destabilizing its mRNA. Mice deficient in TTP develop a complex syndrome of inflammatory diseases. ZFP36 has been shown to interact with

    ZFP36

    ZFP36

    ZFP36

  • LSM6
  • Protein-coding gene in the species Homo sapiens

    Seraphin B (Aug 1999). "Sm and Sm-like proteins assemble in two related complexes of deep evolutionary origin". EMBO J. 18 (12): 3451–62. doi:10.1093/emboj/18

    LSM6

    LSM6

    LSM6

  • J chain
  • Protein-coding gene in the species Homo sapiens

    in order to change the transporter's conformation to an open state. The complex is then transcytosed and the secretory component proteolytically cleaved

    J chain

    J chain

    J_chain

  • UQCRC2
  • Protein-coding gene in the species Homo sapiens

    Cytochrome b-c1 complex subunit 2, mitochondrial (UQCRC2), also known as QCR2, UQCR2, or MC3DN5 is a protein that in humans is encoded by the UQCRC2 gene

    UQCRC2

    UQCRC2

    UQCRC2

  • NDUFB4
  • Protein-coding gene in the species Homo sapiens

    located in the mitochondrial inner membrane and is the largest of the five complexes of the electron transport chain. The NDUFB4 gene, located on the q arm

    NDUFB4

    NDUFB4

    NDUFB4

  • SKIV2L2
  • Protein-coding gene in the species Homo sapiens

    Allmang C, Raijmakers R, et al. (2001). "Three novel components of the human exosome". J. Biol. Chem. 276 (9): 6177–84. doi:10.1074/jbc.M007603200. hdl:2066/186951

    SKIV2L2

    SKIV2L2

    SKIV2L2

  • Tubulin beta-4B chain
  • Protein-coding gene in the species Homo sapiens

    extracellular vesicle cytosol myelin sheath microtubule cytoskeleton extracellular exosome nucleus extracellular matrix extracellular region microtubule cytoskeleton

    Tubulin beta-4B chain

    Tubulin beta-4B chain

    Tubulin_beta-4B_chain

  • TTC37
  • Protein-coding gene in the species Homo sapiens

    tetratricopeptide repeat domains. TTC37 is a component of the Ski complex which is involved in exosome mediated RNA decay. It is localized in the cytoplasmatic

    TTC37

    TTC37

    TTC37

  • Zinc finger C3H1-type containing
  • Protein-coding gene in the species Homo sapiens

    protein binding RNA binding Cellular component extracellular space exosome (RNase complex) nucleolus nucleus Biological process RNA processing Sources:Amigo

    Zinc finger C3H1-type containing

    Zinc finger C3H1-type containing

    Zinc_finger_C3H1-type_containing

  • Integrin beta 5
  • Protein-coding gene in the species Homo sapiens

    Birge RB (2001). "alphavbeta5 integrin recruits the CrkII-Dock180-rac1 complex for phagocytosis of apoptotic cells". Nat. Cell Biol. 2 (12): 899–905.

    Integrin beta 5

    Integrin beta 5

    Integrin_beta_5

  • Stem-cell therapy
  • Use of stem cells to treat or prevent a disease or condition

    eye. Stem cells are being studied for several reasons. The molecules and exosomes released from stem cells are also being studied in an effort to make medications

    Stem-cell therapy

    Stem-cell_therapy

  • Juliane Nguyen
  • American Pharmaceutical Scientist

    research is focused on engineered live biotherapeutics,[better source needed] exosomes and lipid based drug delivery systems. She was awarded a National Science

    Juliane Nguyen

    Juliane_Nguyen

  • RhoC
  • Protein-coding gene in the species Homo sapiens

    Cellular component cytosol plasma membrane cleavage furrow extracellular exosome membrane nucleus intracellular anatomical structure stereocilium Biological

    RhoC

    RhoC

    RhoC

  • NIPBL
  • Protein-coding gene in the species Homo sapiens

    association of cohesin with DNA and is the major subunit of the cohesin loading complex. Heterozygous mutations in NIPBL account for an estimated 60% of case of

    NIPBL

    NIPBL

    NIPBL

  • Small nuclear ribonucleoprotein D2
  • Protein-coding gene in the species Homo sapiens

    M; Lamond A I (December 2000). "Functional analysis of the human CDC5L complex and identification of its components by mass spectrometry". EMBO J. 19

    Small nuclear ribonucleoprotein D2

    Small nuclear ribonucleoprotein D2

    Small_nuclear_ribonucleoprotein_D2

  • CRABP2
  • Protein-coding gene in the species Homo sapiens

    "Crystal structures of cellular retinoic acid binding proteins I and II in complex with all-trans-retinoic acid and a synthetic retinoid". Structure. 2 (12):

    CRABP2

    CRABP2

    CRABP2

  • Ribonucleoprotein particle
  • Protein complex

    of compartments. These include stress granules, processing bodies, and exosomes in somatic cells. Many RNP granules are cell type and/or species specific

    Ribonucleoprotein particle

    Ribonucleoprotein particle

    Ribonucleoprotein_particle

  • GNAS complex locus
  • Gene locus

    GNAS complex locus is a gene locus in humans. Its main product is the heterotrimeric G-protein alpha subunit Gs-α, a key component of G protein-coupled

    GNAS complex locus

    GNAS complex locus

    GNAS_complex_locus

  • Alloantigen recognition
  • extracellular vesicles such as exosomes. Myeloid antigen presenting cells and dendritic cells in particular are one of the major exosome producers. There are known

    Alloantigen recognition

    Alloantigen_recognition

  • EIF3H
  • Protein-coding gene in the species Homo sapiens

    Prt1 protein is an integral part of the eukaryotic initiation factor 3 complex and interacts with p170". J. Biol. Chem. 272 (2): 1110–6. doi:10.1074/jbc

    EIF3H

    EIF3H

    EIF3H

  • RNF103-CHMP3 readthrough
  • Protein-coding gene in the species Homo sapiens

    plasma membrane endosome late endosome membrane extracellular exosome ESCRT III complex cytosol intracellular anatomical structure late endosome cytoplasmic

    RNF103-CHMP3 readthrough

    RNF103-CHMP3 readthrough

    RNF103-CHMP3_readthrough

  • PTGES3
  • Protein-coding gene in the species Homo sapiens

    Yamamoto KR (June 2002). "Disassembly of transcriptional regulatory complexes by molecular chaperones". Science. 296 (5576): 2232–2235. Bibcode:2002Sci

    PTGES3

    PTGES3

    PTGES3

  • GNB4
  • Protein-coding gene in the species Homo sapiens

    transfer via nucleoside diphosphate kinase (NDPK) B and Gbeta subunits. Complex formation of NDPK B with Gbeta gamma dimers and phosphorylation of His-266

    GNB4

    GNB4

    GNB4

  • Transferrin
  • Mammalian protein found in Homo sapiens

    with bovine TF. Transferrin bound to its receptor. Transferrin receptor complex. Transferrin is also associated with the innate immune system. It is found

    Transferrin

    Transferrin

    Transferrin

  • Primase
  • Class of enzymes

    (March 2013). "The archaeal DnaG protein needs Csl4 for binding to the exosome and enhances its interaction with adenine-rich RNAs". RNA Biology. 10 (3):

    Primase

    Primase

  • CUL3
  • Protein-coding gene in humans

    scaffold protein coordinating other components of the CRL complex. Cullin 3-RING complexes can also dimerise via their BTB domains which lead to creation

    CUL3

    CUL3

    CUL3

  • Cytochrome c oxidase subunit 2
  • Enzyme of the respiratory chain encoded by a mitochondrial gene

    subunit of the enzyme Cytochrome c oxidase (EC 1.9.3.1) (Complex IV), an oligomeric enzymatic complex of the mitochondrial respiratory chain involved in the

    Cytochrome c oxidase subunit 2

    Cytochrome c oxidase subunit 2

    Cytochrome_c_oxidase_subunit_2

  • Polymeric immunoglobulin receptor
  • Protein-coding gene in humans

    polymeric isoforms of immunoglobulin A and immunoglobulin M (pIg) and immune complexes. pIgRs are mainly located on the epithelial lining of mucosal surfaces

    Polymeric immunoglobulin receptor

    Polymeric immunoglobulin receptor

    Polymeric_immunoglobulin_receptor

  • Proteasome (prosome, macropain) subunit, alpha 1
  • Protein-coding gene in the species Homo sapiens

    and beta5i) that contributes to the complete assembly of 20S proteasome complex. Th gene PSMA1 encodes a member of the peptidase T1A family, that is a

    Proteasome (prosome, macropain) subunit, alpha 1

    Proteasome (prosome, macropain) subunit, alpha 1

    Proteasome_(prosome,_macropain)_subunit,_alpha_1

  • Ravi Radhakrishnan
  • American engineer and academic

    tumor progression by stimulating exosome secretion from cancer cells via an Akt-Rab8 pathway, and demonstrated that exosomes derived under these conditions

    Ravi Radhakrishnan

    Ravi_Radhakrishnan

  • ARPC1B
  • Mammalian protein found in Homo sapiens

    Actin-related protein 2/3 complex subunit 1B is a protein that in humans is encoded by the ARPC1B gene. This gene encodes one of seven subunits of the

    ARPC1B

    ARPC1B

    ARPC1B

  • Syntenin-1
  • Protein found in humans

    membrane cell junction endoplasmic reticulum membrane raft extracellular exosome cytoskeleton nucleus extracellular region extracellular space nucleoplasm

    Syntenin-1

    Syntenin-1

    Syntenin-1

  • PSMA5
  • Protein found in humans

    beta2i, beta5i) that contributes to the complete assembly of 20S proteasome complex. The eukaryotic proteasome recognized degradable proteins, including damaged

    PSMA5

    PSMA5

    PSMA5

  • PSMB9
  • Protein found in humans

    The resulting proteasome complex becomes the so-called immunoproteasome. An essential function of the modified proteasome complex, the immunoproteasome,

    PSMB9

    PSMB9

    PSMB9

  • Interferometric scattering microscopy
  • Microscopy methods

    and complex, speckle-like backgrounds. iSCAT has been used to investigate nanoparticles such as viruses, proteins, lipid vesicles, DNA, exosomes, metal

    Interferometric scattering microscopy

    Interferometric scattering microscopy

    Interferometric_scattering_microscopy

  • VPS4A
  • Protein-coding gene in the species Homo sapiens

    Posada MM, Blazer LL, Zhao T, Rosania GR (2007). "The role of the VPS4A-exosome pathway in the intrinsic egress route of a DNA-binding anticancer drug"

    VPS4A

    VPS4A

    VPS4A

  • DDB1
  • Protein-coding gene in the species Homo sapiens

    as a core component of the CUL4A- and CUL4B-based E3 ubiquitin ligase complexes. DDB1 serves as a bridge or adaptor protein which interacts with dozens

    DDB1

    DDB1

    DDB1

  • CACTIN
  • Protein-coding gene in humans

    doi:10.1016/j.fsi.2014.10.014. PMID 25462455. "CACTIN cactin, spliceosome C complex subunit [Homo sapiens (human)] - Gene - NCBI". www.ncbi.nlm.nih.gov. Retrieved

    CACTIN

    CACTIN

    CACTIN

  • CCT3
  • Protein-coding gene in humans

    T-complex protein 1 subunit gamma is a protein that in humans is encoded by the CCT3 gene. This gene encodes a molecular chaperone that is member of the

    CCT3

    CCT3

    CCT3

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EXOSOME COMPLEX

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EXOSOME COMPLEX

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EXOSOME COMPLEX

  • Complexness
  • n.

    The state of being complex; complexity.

  • Complexus
  • n.

    A complex; an aggregate of parts; a complication.

  • Urosome
  • n.

    The abdomen, or post-abdomen, of arthropods.

  • Exospore
  • n.

    The extreme outer wall of a spore; the epispore.

  • Complexity
  • n.

    The state of being complex; intricacy; entanglement.

  • Exostome
  • n.

    The small aperture or foremen in the outer coat of the ovule of a plant.

  • Exosmose
  • n.

    The passage of gases, vapors, or liquids thought membranes or porous media from within outward, in the phenomena of osmose; -- opposed to endosmose. See Osmose.

  • Exosmosis
  • n.

    See Exosmose.

  • Exosmotic
  • a.

    Pertaining to exosmose.

  • Osmose
  • n.

    The tendency in fluids to mix, or become equably diffused, when in contact. It was first observed between fluids of differing densities, and as taking place through a membrane or an intervening porous structure. The more rapid flow from the thinner to the thicker fluid was then called endosmose, and the opposite, slower current, exosmose. Both are, however, results of the same force. Osmose may be regarded as a form of molecular attraction, allied to that of adhesion.

  • Merosome
  • n.

    One of the serial segments, or metameres, of which the bodies of vertebrate and articulate animals are composed.

  • Exosse-ous
  • a.

    Boneless.

  • Complexional
  • a.

    Of or pertaining to constitutional complexion.

  • Complexionary
  • a.

    Pertaining to the complexion, or to the care of it.

  • Complexities
  • pl.

    of Complexity

  • Transudation
  • n.

    Same as Exosmose.

  • Complexity
  • n.

    That which is complex; intricacy; complication.

  • Complexly
  • adv.

    In a complex manner; not simply.

  • Complexioned
  • a.

    Having (such) a complexion; -- used in composition; as, a dark-complexioned or a ruddy-complexioned person.