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Search references for DDB1. Phrases containing DDB1
See searches and references containing DDB1!DDB1
Protein-coding gene in the species Homo sapiens
protein that in humans is encoded by the DDB1 gene. The gene's position is on chromosome 11q12-q13. The DDB1 gene encodes the large subunit of DNA damage-binding
DDB1
Medical condition multisystem disorder
is a heterodimeric protein composed of two subunits. The larger subunit DDB1 primarily functions as a core component of CUL4A- and CUL4B-based E3 ubiquitin
Xeroderma_pigmentosum
DNA repair mechanism
the XPC-Rad23B complex is responsible for distortion recognition, while DDB1 and DDB2 (XPE) can also recognize some types of damage caused by UV light
Nucleotide_excision_repair
Set of ethnic groups in Southeast Asia and Andaman islands
of the dark pigmentation in TIAs could have resulted from parallel (e.g., DDB1/DAK) or genetic convergence driven by admixture (e.g., MTHFD1 and RAD18)
Negrito
Protein in humans
of cereblon, DDB1 forms a complex with DDB2 that functions as a DNA damage-binding protein. Furthermore, cereblon and DDB2 bind to DDB1 in a competitive
Cereblon
Protein-coding gene in the species Danio rerio
DDB1- and CUL4-associated factor 11 also known as WD Repeat Domain 23 (WDR23) is a protein that in humans is encoded by the DCAF11 gene. DCAF11 is a WD40
DCAF11
Protein found in humans
transient receptor potential channel protein-protein interaction domains, DDB1 binding elements, and a prenylated C-terminus. Reduced expression or disruption
WDTC1
Protein-coding gene in the species Homo sapiens
DDB1 and CUL4 associated factor 8 is a protein that in humans is encoded by the DCAF8 gene. This gene encodes a WD repeat-containing protein that interacts
DCAF8
Protein-coding gene in humans
possesses. CUL4B binds to the beta-propeller of the DDB1 adaptor protein which interacts with numerous DDB1-CUL4-Associated Factors (DCAFs). This interaction
CUL4B
Protein-coding gene in the species Homo sapiens
DDB1 and CUL4 associated factor 15 is a protein that in humans is encoded by the DCAF15 gene. DCAF15 forms a complex with CUL4A or CUL4B that has E3 ubiquitin
DCAF15
Pair of enantiomers
CRL4CRBN E3 ubiquitin ligase, a complex consisting of DNA-binding protein 1 (DDB1), cullin 4a (CUL4A), regulator of cullins 1 (ROC1), and cereblon (CRBN).
Lenalidomide
Group of transport proteins
(DDB1) as part of a CUL4–DDB1 E3 ubiquitin ligase complex. When bound to Vpr, VprBP allows Vpr to modulate the catalytic activity of the CUL4–DDB1 complex
Vpr
Ethnic group of Andaman Islands
of the dark pigmentation in TIAs could have resulted from parallel (e.g., DDB1/DAK) or genetic convergence driven by admixture (e.g., MTHFD1 and RAD18)
Onge
Protein family
formation. It interacts with DDB1 (Damaged DNA Binding Protein 1) redirecting the ubiquitin ligase activity of the CUL4-DDB1 E3 complexes, which are intimately
HBx
Cellular mechanism
and deacetylase complex NuRD. DDB2 occurs in a heterodimeric complex with DDB1. This complex further complexes with the ubiquitin ligase protein CUL4A and
DNA_repair
Class of chemical compounds
degrade RBM39/RBM23. [see also indisulam, tasisulam] CR8 [CDK12-DDB1] Links CDK12 to CRL4-DDB1 ligase, triggering CDK12-associated cyclin K degradation. PF-07208254
Molecular_glue
Russian journalist
Видеоархив выпусков Наши Олимпийские медали! Страничка о Дмитрии Борисове на сайте Первого канала Дмитрий Борисов на сайте Эхо Москвы @ddb1 v t e v t e v t e
Dmitry_Borisov_(anchorman)
Protein-coding gene in humans
N-terminus, CUL4A binds to the beta-propeller of the DDB1 adaptor protein which interacts with numerous DDB1-CUL4-Associated Factors (DCAFs). As a result, the
CUL4A
Protein-coding gene in the species Homo sapiens
protein". Huang J, Chen J (July 2008). "VprBP targets Merlin to the Roc1-Cul4A-DDB1 E3 ligase complex for degradation". Oncogene. 27 (29): 4056–64. doi:10.1038/onc
VPRBP
Letter "Sa" in Indic scripts
56880 D806 DE30 55301 56371 D805 DC33 55303 56365 D807 DC2D 55300 56753 D804 DDB1 Numeric character reference ས ས ྶ ྶ ꡛ ꡛ
Sa_(Indic)
Mammalian protein found in Homo sapiens
group of genes. Merlin (protein) has been shown to interact with: CUL4A, DDB1, EZR, HGS, MED28, RIT1, SDCBP, SPTBN1, and VPRBP. GRCh38: Ensembl release
Merlin_(protein)
Process of removing one or more methyl groups from a molecule
2 (8): 1843–1845. doi:10.1016/j.checat.2022.07.005. hdl:11370/fee939a3-ddb1-4737-a355-88033a066151. W. Boerjan; J. Ralph; M. Baucher (June 2003). "Lignin
Demethylation
Human chromosome
(1q21) CSRP1: Cysteine and glycine rich protein 1 DCAF8: encoding protein DDB1 and CUL4 associated factor 8 DDX59: DEAD-box helicase 59 DEL1Q21: encoding
Chromosome_1
Protein-coding gene in the species Homo sapiens
DDB1 and CUL4 associated factor 17 is a protein that in humans is encoded buy the DCAF17 gene. DCAF17 is a nuclear transmembrane protein that associates
DCAF17
protein subunits, a large subunit DDB1 (p127) and a small subunit DDB2 (p48). When cells are exposed to UV radiation, DDB1 moves from the cytosol to the nucleus
DNA_damage-binding_protein
Mechanism in molecular recognition
DNA in discrete steps before forming long-lived, nonmotile UV-DDB dimers (DDB1-DDB2)2 at sites of damage. Analysis of the rates of dissociation for the
Conformational_proofreading
Protein-coding gene in the species Homo sapiens
of DDB2 (a 48 kDa molecular weight protein) is essential for binding to DDB1 (a larger 127 kDa protein). Together, the two proteins form a UV-damaged
DDB2
Medical condition
the mutant R317C protein significantly decreases the binding of DCAF8 to DDB1, which ended up negatively impacting the recruitment of the E3 ubiquitin
Autosomal dominant Charcot–Marie–Tooth disease type 2 with giant axons
Autosomal_dominant_Charcot–Marie–Tooth_disease_type_2_with_giant_axons
Mammalian protein found in Homo sapiens
Unconfirmed C19orf68 Chromosome 19 Open Reading Frame 68 Unknown Unconfirmed DCAF7 DDB1 And CUL4 Associated Factor 7 It's been shown to function as a scaffold protein
CEFIP
Damage in DNA which occurs naturally
[citation needed] After irradiation with UV light, DDB2, in a complex with DDB1, the ubiquitin ligase protein CUL4A and the RING finger protein ROC1, associates
DNA damage (naturally occurring)
DNA_damage_(naturally_occurring)
Protein-coding gene in the species Homo sapiens
1002/rcm.1746. PMID 15570572. Higa LA, Wu M, Ye T, et al. (2006). "CUL4-DDB1 ubiquitin ligase interacts with multiple WD40-repeat proteins and regulates
SMU1
Protein-coding gene in the species Homo sapiens
Transformation/transcription domain-associated protein, TAF12, TAF10, TAF4 and DDB1. GRCh38: Ensembl release 89: ENSG00000196284 – Ensembl, May 2017 GRCm38:
Transcription initiation protein SPT3 homolog
Transcription_initiation_protein_SPT3_homolog
American politician
Commonwealth of Massachusetts. Oct. 14, 2006 <http://mass.gov/legis/member/ddb1.htm Archived 2006-10-12 at the Wayback Machine>. "Rep. Blumer dies while
Deborah_Blumer
Undesirable occurrence in eukaryotic cells
various higher order eukaryotes as well. Cdt1 is degraded through the Cul4–Ddb1–Cdt2 E3 ubiquitin ligase complex so that DNA licensing control is maintained
DNA_re-replication
Protein-coding gene in the species Homo sapiens
Higa LA, Wu M, Ye T, Kobayashi R, Sun H, Zhang H (November 2006). "CUL4-DDB1 ubiquitin ligase interacts with multiple WD40-repeat proteins and regulates
GRWD1
Protein-coding gene in the species Homo sapiens
differentiation in neural stem cells. GCN5L2 has been shown to interact with: DDB1, Ku70, Ku80, TADA2L, TAF9, and Transcription initiation protein SPT3 homolog
KAT2A
Protein-coding gene in the species Homo sapiens
regulate p53 polyubiquitination and protein stability through MDM2 and CUL4A/DDB1 complexes". Cell Cycle. 5 (15): 1719–29. doi:10.4161/cc.5.15.3150. PMID 16861890
DTL_(gene)
Nuclear protein that binds to CREB
Actr Ap-1 Apc5 Apc7 Atr BRCA1 C-FOS C-JUN C-MYB Chrebp CITED2 Ddb1 (p127) Ddb2 (p48) Ddx3 Dhx9 DNA2 helicase E1A E2F Elk1 ER Ets1 Fen1 Foxo1 Gal4 GATA1
CREB-binding_protein
Protein complex formed during initiation of DNA replication
Cdt1 proteolysis in fission yeast through a pathway dependent on Cdt2 and Ddb1". EMBO Reports. 7 (11): 1134–1139. doi:10.1038/sj.embor.7400827. PMC 1679788
Pre-replication_complex
Protein-coding gene in the species Homo sapiens
DCAF7 Identifiers Aliases DCAF7, AN11, HAN11, SWAN-1, WDR68, DDB1 and CUL4 associated factor 7 External IDs OMIM: 605973; MGI: 1919083; HomoloGene: 55930;
WDR68
Protein
P21 has been shown to interact with: Nrf2 BCCIP, CIZ1, CUL4A, CCNE1, CDK, DDB1, DTL, GADD45A, GADD45G, HDAC, PCNA, PIM1, TK1, and TSG101. GRCh38: Ensembl
P21
American biochemist and structural biologist
Angers, S., Li, T., Yi, X. et al. Molecular architecture and assembly of the DDB1–CUL4A ubiquitin ligase machinery. Nature 443, 590–593 (2006). https://doi
Ning_Zheng
South Korean molecular geneticist (born 1970)
(2012). "EZH2 Generates a Methyl Degron that is Recognized by the DCAF1/DDB1/CUL4 E3 Ubiquitin Ligase Complex". Molecular Cell. 48 (4): 572–86. doi:10
Baek_Sung-hee
for replication in fission yeast Two E3 ubiquitin ligases, SCF-Skp2 and DDB1-Cul4, target human Cdt1 for proteolysis Accurate Processing of a Eukaryotic
Zoi_Lygerou
Protein-coding gene in the species Homo sapiens
"WD40 protein FBW5 promotes ubiquitination of tumor suppressor TSC2 by DDB1-CUL4-ROC1 ligase". Genes & Development. 22 (7): 866–71. doi:10.1101/gad.1624008
FBXW5
Protein-coding gene in the species Homo sapiens
S2CID 7827573. Higa LA, Wu M, Ye T, Kobayashi R, Sun H, Zhang H (Nov 2006). "CUL4-DDB1 ubiquitin ligase interacts with multiple WD40-repeat proteins and regulates
WDR26
Protein-coding gene in the species Homo sapiens
boxSkp2 SCF Ubiquitin Ligase Complex 1u6g: Crystal Structure of The Cand1-Cul1-Roc1 Complex 2hye: Crystal Structure of the DDB1-Cul4A-Rbx1-SV5V Complex
RBX1
Class of algae
(Chlorophyta: Prasinophyceae) Tevatia R, Oyler GA (2018-01-02). "Evolution of DDB1-binding WD40 (DWD) in the viridiplantae". PLOS ONE. 13 (1) e0190282. Bibcode:2018PLoSO
Prasinophyte
Protein-coding gene in humans
Higa LA, Wu M, Ye T, Kobayashi R, Sun H, Zhang H (November 2006). "CUL4-DDB1 ubiquitin ligase interacts with multiple WD40-repeat proteins and regulates
CIAO1
Protein-coding gene in the species Homo sapiens
PMID 18303015. Huang J, Chen J (July 2008). "VprBP targets Merlin to the Roc1-Cul4A-DDB1 E3 ligase complex for degradation". Oncogene. 27 (29): 4056–64. doi:10.1038/onc
RIT1
Protein-coding gene in humans
a heterodimeric complex with TGF-beta receptor type-1, and binds TGF-beta. DCAF5 DDB1 and CUL4 Associated Factor 5 Involved in protein ubiquitination.
CXorf58
Letter "Gha" in Indic scripts
240 145 130 144 F0 91 82 90 UTF-16 55301 56849 D805 DE11 55302 56753 D806 DDB1 55302 56927 D806 DE5F 43018 A80A 55303 56695 D807 DD77 55300 56464 D804 DC90
Gha_(Indic)
German structural and chemical biologist
(December 2008). "Structural Basis of UV DNA-Damage Recognition by the DDB1–DDB2 Complex". Cell. 135 (7): 1213–1223. doi:10.1016/j.cell.2008.10.045.
Nicolas_H._Thomä
HGNC:28360; Q9BW61 4048 DDAH1 HGNC:2715; O94760 4049 DDAH2 HGNC:2716; O95865 4050 DDB1 HGNC:2717; Q16531 4051 DDB2 HGNC:2718; Q92466 4052 DDC HGNC:2719; P20711
List of human protein-coding genes 2
List_of_human_protein-coding_genes_2
Protein-coding gene in the species Homo sapiens
PMID 16723661. Higa LA, Wu M, Ye T, Kobayashi R, Sun H, Zhang H (Nov 2006). "CUL4-DDB1 ubiquitin ligase interacts with multiple WD40-repeat proteins and regulates
WDR57
British academic
Rappsilber, Juri; Allshire, Robin C (2012). "Raf1 is a DCAF for the Rik1 DDB1-Like Protein and Has Separable Roles in siRNA Generation and Chromatin Modification"
Robin_Allshire
Protein-coding gene in the species Homo sapiens
PMID 16189514. S2CID 4427026. Higa LA, Wu M, Ye T, et al. (2006). "CUL4-DDB1 ubiquitin ligase interacts with multiple WD40-repeat proteins and regulates
TLE2
Family of mosses
6f98e25d-7341-43ae-bf42-0867184f111a Open Tree of Life: 405426 Plazi: E9733414-8AE9-48BD-DDB1-08D923F31F41 Tropicos: 35001450 WFO: wfo-7000000019 WoRMS: 292806
Amblystegiaceae
Protein-coding gene in the species Homo sapiens
Higa LA, Wu M, Ye T, Kobayashi R, Sun H, Zhang H (November 2006). "CUL4-DDB1 ubiquitin ligase interacts with multiple WD40-repeat proteins and regulates
WDR12
Indian-born American biochemist and cancer researcher
Dutta, A (10 March 2006). "PCNA is a cofactor for Cdt1 degradation by CUL4/DDB1-mediated N-terminal ubiquitination". The Journal of Biological Chemistry
Anindya_Dutta
Protein-coding gene in the species Homo sapiens
is mediated by interaction with the damage-specific DNA-binding protein DDB1". Proceedings of the National Academy of Sciences of the United States of
Cyclin_O
Protein-coding gene in the species Homo sapiens
PMID 16604156. Higa LA, Wu M, Ye T, Kobayashi R, Sun H, Zhang H (Nov 2006). "CUL4-DDB1 ubiquitin ligase interacts with multiple WD40-repeat proteins and regulates
RBBP5
DDB1
DDB1
DDB1
DDB1
Girl/Female
Muslim
Cloud, Joyful
Boy/Male
English
From the manor house meadow.
Girl/Female
Tamil
East
Boy/Male
American, Australian, British, English, French, German, Latin
Name of a King; Renowned Fighter; Famous Battle
Boy/Male
Arabic, Muslim
Lamp of the Religion Islam
Boy/Male
Australian, Celtic, Christian, Irish, Welsh
Small; Little
Boy/Male
Hindu, Indian, Punjabi, Sikh
Forever in Peace and Delight
Surname or Lastname
English
English : occupational name for a sifter of flour and meal, from an agent derivative of Middle English rid(e)len ‘to sift’ (from Old English hriddel ‘sieve’).German : topographic name from Bavarian Ridel ‘hill’.Perhaps an altered spelling of German Riedler, a variant of Rieder or Riedel.
Girl/Female
Hindu, Indian, Marathi
Knowledge
Boy/Male
Hindu, Indian
Merciful; Future
DDB1
DDB1
DDB1
DDB1
DDB1