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Calcium channel blocker medication
Diltiazem, sold under the brand name Cardizem among others, is a nondihydropyridine calcium channel blocker medication used to treat high blood pressure
Diltiazem
Inflammation due to damage of skin capillaries when blood perfuses into nearby tissue
available in an oral pill but can be compounded into a topical formula. Diltiazem, another vasodilator, is also sometimes used. The word is a compound of
Chilblains
Enzyme that metabolizes substances by oxidation
1997). "Role of CYP3A4 in human hepatic diltiazem N-demethylation: inhibition of CYP3A4 activity by oxidized diltiazem metabolites". The Journal of Pharmacology
CYP3A4
Lipid-lowering medication
recommended in people taking the calcium channel blockers, verapamil and diltiazem, as well as those taking amiodarone. Common side effects (>1% incidence)
Simvastatin
Drug class
single benzene attached to the ring, while dibenzothiazepines have two. Diltiazem, a benzothiazepine, is a calcium channel blocker intermediate in properties
Thiazepine
Human liver enzyme
doi:10.2174/138920010794233495. PMC 3028383. PMID 20942780. "DILTIAZEM HCL CD- diltiazem hydrochloride capsule, coated, extended release". DailyMed. 1
CYP2D6
Amiodarone Dofetilide Sotalol Type IV (slow calcium channel blockers) Diltiazem Verapamil Type V Adenosine Digoxin Class of antihypertensives that work
List of cardiac pharmaceutical agents
List_of_cardiac_pharmaceutical_agents
Calcium channel blocker medication
calcium channel blockers such as dihydropyridine derivatives, verapamil and diltiazem, flunarizine has low affinity to voltage-dependent calcium channels. It
Flunarizine
Blood pressure medication
digoxin, diltiazem, ivabradine, or verapamil. Also, combination of carvedilol with non-dihydropyridine calcium channel blockers, including diltiazem and verapamil
Carvedilol
Drug used to treat angina
phenobarbital. For drugs that are moderate CYP3A inhibitors, such as diltiazem, verapamil, and erythromycin, the dose of ranolazine should be reduced
Ranolazine
Chemical compound
inhibit CYP3A4, such as itraconazole, erythromycin, ketoconazole, and diltiazem, are known to interact with cilostazol. The proton pump inhibitor omeprazole
Cilostazol
Drugs that disrupt movement of calcium across calcium channels
reflex cardiac stimulation caused by dihydropyridines.[citation needed] Diltiazem (Cardizem) (also used experimentally to prevent migraine)[citation needed]
Calcium_channel_blocker
Medication used to treat insomnia
overall exposure to daridorexant by 1.5-fold; the moderate CYP3A4 inhibitor diltiazem (240 mg) increased exposure to daridorexant by 2.4-fold; and the strong
Daridorexant
Medication used to treat insomnia
levels by about 1.25-fold, combination with the moderate CYP3A4 inhibitor diltiazem increased suvorexant overall exposure by 2.05-fold and peak levels by
Suvorexant
Gamma-aminobutyric acid analog
Sornidipine Teludipine Tiamdipine Trombodipine Vatanidipine; Diltiazem derivatives: Clentiazem Diltiazem Iprotiazem Nictiazem Siratiazem; Phenylalkylamines: Anipamil
Gabapentin
Medication against high blood pressure
are one such class of drugs. Others include the calcium-channel blocker diltiazem, the antibiotic clarithromycin, and possibly some antifungals. Amlodipine
Amlodipine
Antihypertensive drug of the calcium channel blocker class
contrast to the non-dihydropyridine calcium channel blockers verapamil and diltiazem, it does not significantly act on calcium channels in the atrioventricular
Lercanidipine
Medical condition
or non-dihydropyridine calcium channel blockers (such as verapamil or diltiazem). Both adenosine and beta blockers may cause tightening of the airways
AV nodal reentrant tachycardia
AV_nodal_reentrant_tachycardia
Diseases in which skeletal and visceral muscles break down over time
glucocorticoids (Deflazacort, Vamorolone); calcium channel blockers (Diltiazem); to slow skeletal and cardiac muscle degeneration, anticonvulsants to
Muscular_dystrophy
Beta blocker drug
amiodarone, cardiac glycosides, calcium channel blockers like verapamil and diltiazem, ACE inhibitors, alpha blockers like prazosin, catecholamine-depleting
Propranolol
Tropane alkaloid and stimulant drug
Sornidipine Teludipine Tiamdipine Trombodipine Vatanidipine; Diltiazem derivatives: Clentiazem Diltiazem Iprotiazem Nictiazem Siratiazem; Phenylalkylamines: Anipamil
Cocaine
Antibiotic medication
drugs that prolong the metabolism of erythromycin (like verapamil or diltiazem) by interfering with CYP3A4. Hence, erythromycin should not be administered
Erythromycin
Protein found in humans
P-glycoprotein include: amiodarone, clarithromycin, ciclosporin, colchicine, diltiazem, erythromycin, felodipine, ketoconazole, lansoprazole, omeprazole and
P-glycoprotein
Type of muscular dystrophy
glucocorticoids (Deflazacort, Vamorolone); calcium channel blockers (Diltiazem); to slow skeletal and cardiac muscle degeneration, anticonvulsants to
Duchenne_muscular_dystrophy
Oral cough medication
Sornidipine Teludipine Tiamdipine Trombodipine Vatanidipine; Diltiazem derivatives: Clentiazem Diltiazem Iprotiazem Nictiazem Siratiazem; Phenylalkylamines: Anipamil
Benzonatate
Biotechnology company acquired in 2010
in 2006. Ocinaplon for anxiety disorders. A proprietary formulation of diltiazem DOV 102,677, for the treatment of Parkinson's disease, restless leg syndrome
DOV_Pharmaceutical
Genetic muscle disorder
glucocorticoids (Deflazacort, Vamorolone); calcium channel blockers (Diltiazem); to slow skeletal and cardiac muscle degeneration, anticonvulsants to
Becker_muscular_dystrophy
Difference between systolic and diastolic blood pressure
beta-blocker), captopril (an ACE inhibitor), clonidine (a central α2-agonist), diltiazem (a calcium channel blocker), and prazosin (an α1-blocker) on pulse pressure
Pulse_pressure
Chemical compound
1,4-Thiazepine is a thiazepine. Diltiazem is based upon this structure. Katritzky, A. R.; Pozharskii, A. F. (2000). Handbook of Heterocyclic Chemistry
1,4-Thiazepine
Non-opioid analgesic drug
Sornidipine Teludipine Tiamdipine Trombodipine Vatanidipine; Diltiazem derivatives: Clentiazem Diltiazem Iprotiazem Nictiazem Siratiazem; Phenylalkylamines: Anipamil
Suzetrigine
Local anesthetic
Sornidipine Teludipine Tiamdipine Trombodipine Vatanidipine; Diltiazem derivatives: Clentiazem Diltiazem Iprotiazem Nictiazem Siratiazem; Phenylalkylamines: Anipamil
Lidocaine
Blood vessels narrowing due to arterial spasm
L-type calcium channel blockers (notably nimodipine, as well as verapamil, diltiazem, nifedipine) and beta-receptor antagonists (more commonly known as beta
Vasospasm
Anticonvulsant medication
Sornidipine Teludipine Tiamdipine Trombodipine Vatanidipine; Diltiazem derivatives: Clentiazem Diltiazem Iprotiazem Nictiazem Siratiazem; Phenylalkylamines: Anipamil
Lamotrigine
Break or tear in anal canal skin
first-line treatment. Topical therapy includes nitroglycerin ointment and diltiazem (calcium channel blocker) ointment. Nitroglycerin has the side effect
Anal_fissure
Heart rate below the normal range
blockers like propranolol, calcium channel blockers like verapamil and diltiazem, cardiac glycosides like digoxin, alpha-2 agonists like clonidine, and
Bradycardia
Dissociative anesthetic and anti-depressant
Sornidipine Teludipine Tiamdipine Trombodipine Vatanidipine; Diltiazem derivatives: Clentiazem Diltiazem Iprotiazem Nictiazem Siratiazem; Phenylalkylamines: Anipamil
Ketamine
Irregular beating of the atria of the heart
bisoprolol, or nebivolol) Non-dihydropyridine calcium channel blockers (e.g., diltiazem or verapamil) Cardiac glycosides (e.g., digoxin) – have less use, apart
Atrial_fibrillation
Medication used to treat anxiety disorders
been reported in a co-ingestion of 450 mg buspirone with alprazolam, diltiazem, alcohol, and cocaine. Buspirone has been shown in vitro to be metabolized
Buspirone
Chemical compound
curve (area under the curve (AUC)). Less potent CYP3A4 inhibitors such as diltiazem have a less pronounced effect on this parameters, which is not considered
Silodosin
Medical condition
reassurance and topical treatment with a calcium channel blocker such as diltiazem, or nifedipine ointment, salbutamol inhalation, and topical nitroglycerine
Proctalgia_fugax
Agent that alters the strength of muscular contractions
agents include: Beta blockers Non-dihydropyridine Calcium channel blockers Diltiazem Verapamil Class IA antiarrhythmics such as Quinidine Procainamide Disopyramide
Inotrope
Antihistamine medication
Sornidipine Teludipine Tiamdipine Trombodipine Vatanidipine; Diltiazem derivatives: Clentiazem Diltiazem Iprotiazem Nictiazem Siratiazem; Phenylalkylamines: Anipamil
Diphenhydramine
Episodes of abnormally fast heart rhythm
If unsuccessful or the PSVT recurs, calcium channel blockers, such as diltiazem or verapamil, are recommended. Adenosine may be safely used during pregnancy
Paroxysmal supraventricular tachycardia
Paroxysmal_supraventricular_tachycardia
Medication used to treat epilepsy and migraine
Sornidipine Teludipine Tiamdipine Trombodipine Vatanidipine; Diltiazem derivatives: Clentiazem Diltiazem Iprotiazem Nictiazem Siratiazem; Phenylalkylamines: Anipamil
Topiramate
Chemical compound
expected with known P-glycoprotein inhibitors such as amiodarone, bepridil, diltiazem, ciclosporin, itraconazole, quinine, quinidine, spironolactone, and verapamil
Alvimopan
Chemical reaction
0]undec-7-ene (DBU) as the key step in the efficient synthesis of Diltiazem (Figure 6.) Diltiazem is a commercially available pharmaceutical which acts as a
Juliá–Colonna_epoxidation
Former pharmaceutical company merged with Allergan
and community-acquired pneumonia caused by susceptible bacteria Tiazac (diltiazem hydrochloride) for hypertension and chronic stable angina pectoris Thyrolar
Forest_Laboratories
Pain in the head, neck, or face
stop sex if they develop a headache. Medications such as propranolol and diltiazem can also be helpful. hypnic headache: a moderate-severe headache that
Headache
Class of depressant drugs derived from barbituric acid
Sornidipine Teludipine Tiamdipine Trombodipine Vatanidipine; Diltiazem derivatives: Clentiazem Diltiazem Iprotiazem Nictiazem Siratiazem; Phenylalkylamines: Anipamil
Barbiturate
Chemical compound
the original on 23 March 2019. Kishioka S, Ko MC, Woods JH (May 2000). "Diltiazem enhances the analgesic but not the respiratory depressant effects of morphine
Etonitazene
Heart rhythm medication
contractility.[citation needed] Class IV agents include verapamil and diltiazem. Since the development of the original Vaughan Williams classification
Antiarrhythmic_agent
Chemical compound
Sornidipine Teludipine Tiamdipine Trombodipine Vatanidipine; Diltiazem derivatives: Clentiazem Diltiazem Iprotiazem Nictiazem Siratiazem; Phenylalkylamines: Anipamil
Solifenacin
Liver damage caused by a drug or chemical
Amiodarone, Cimetidine, Ciprofloxacin, Fluconazole, Fluoxetine, Erythromycin, Isoniazid, Diltiazem Caffeine, Clozapine, Omeprazole, Losartan, Theophylline
Hepatotoxicity
Anticonvulsant medication
Sornidipine Teludipine Tiamdipine Trombodipine Vatanidipine; Diltiazem derivatives: Clentiazem Diltiazem Iprotiazem Nictiazem Siratiazem; Phenylalkylamines: Anipamil
Pregabalin
Swelling of gums due to side effect of medications
Sodium valproate Immunoregulating drugs Ciclosporine Tacrolimus Sirolimus Calcium channel blockers Nifedipine Verapamil Diltiazem Amlodipine Felodipine
Drug-induced gingival enlargement
Drug-induced_gingival_enlargement
Chemical compound
derivative of diltiazem. Giasson S, Garceau D, Homsy W, Dumont L (October 1995). "Pharmacodynamics and pharmacokinetics of clentiazem and diltiazem in closed-chest
Clentiazem
Chemical compound
Sornidipine Teludipine Tiamdipine Trombodipine Vatanidipine; Diltiazem derivatives: Clentiazem Diltiazem Iprotiazem Nictiazem Siratiazem; Phenylalkylamines: Anipamil
Mirogabalin
Neurotoxin
Sornidipine Teludipine Tiamdipine Trombodipine Vatanidipine; Diltiazem derivatives: Clentiazem Diltiazem Iprotiazem Nictiazem Siratiazem; Phenylalkylamines: Anipamil
Tetrodotoxin
Chemical compound
Sornidipine Teludipine Tiamdipine Trombodipine Vatanidipine; Diltiazem derivatives: Clentiazem Diltiazem Iprotiazem Nictiazem Siratiazem; Phenylalkylamines: Anipamil
Meclizine
Anticonvulsant medication
Sornidipine Teludipine Tiamdipine Trombodipine Vatanidipine; Diltiazem derivatives: Clentiazem Diltiazem Iprotiazem Nictiazem Siratiazem; Phenylalkylamines: Anipamil
Oxcarbazepine
Triazolobenzodiazepine sleep medication
effectiveness of triazolam. Other important interactions include cimetidine, diltiazem, fluconazole, grapefruit juice, isoniazid, itraconazole, nefazodone, rifampicin
Triazolam
Discontinued antidepressant medication
Bristol-Myers Squibb), has since been discontinued and is no longer marketed. Diltiazem Tofenacin Ganellin CR, Triggle DJ, Macdonald F (1997). Dictionary of pharmacological
Tiazesim
Medical condition in which calcium deposits form in the skin
manifests as solid, varying-sized, skin-colored subcutaneous nodules. Diltiazem, a calcium channel blocker, has been a mainstay of medical treatment for
Calcinosis_cutis
Antifungal chemical compound
Sornidipine Teludipine Tiamdipine Trombodipine Vatanidipine; Diltiazem derivatives: Clentiazem Diltiazem Iprotiazem Nictiazem Siratiazem; Phenylalkylamines: Anipamil
Ketoconazole
French multinational pharmaceutical and healthcare company
(Irbesartan), for hypertension, marketed by Bristol-Myers Squibb. Cardizem (Diltiazem), for hypertension, Now owned by Bausch Health. Cholestagel (Colesevelam)
Sanofi
Medication
Sornidipine Teludipine Tiamdipine Trombodipine Vatanidipine; Diltiazem derivatives: Clentiazem Diltiazem Iprotiazem Nictiazem Siratiazem; Phenylalkylamines: Anipamil
Sotalol
Healthcare professional working outside of hospitals
used to treat severe pain. Beta and calcium channel blockers such as diltiazem, metoprolol and verapamil used to slow down excessively high heart rates
Paramedic
Chemical compound
may interact with the following drugs: Calcium channel blockers of the diltiazem/verapamil type: Intravenous treatment with dantrolene and concomitant
Dantrolene
Muscle relaxant medication
Sornidipine Teludipine Tiamdipine Trombodipine Vatanidipine; Diltiazem derivatives: Clentiazem Diltiazem Iprotiazem Nictiazem Siratiazem; Phenylalkylamines: Anipamil
Baclofen
Medication to treat high blood pressure and alopecia
Sornidipine Teludipine Tiamdipine Trombodipine Vatanidipine; Diltiazem derivatives: Clentiazem Diltiazem Iprotiazem Nictiazem Siratiazem; Phenylalkylamines: Anipamil
Minoxidil
Benzodiazepine used for anesthesia and procedural sedation
inhibitors, nefazodone, sertraline, grapefruit, fluoxetine, erythromycin, diltiazem, and clarithromycin inhibit the metabolism of midazolam, leading to a
Midazolam
Local anesthetic drug
Sornidipine Teludipine Tiamdipine Trombodipine Vatanidipine; Diltiazem derivatives: Clentiazem Diltiazem Iprotiazem Nictiazem Siratiazem; Phenylalkylamines: Anipamil
Procaine
Species of plant
Sornidipine Teludipine Tiamdipine Trombodipine Vatanidipine; Diltiazem derivatives: Clentiazem Diltiazem Iprotiazem Nictiazem Siratiazem; Phenylalkylamines: Anipamil
Kava
Failure of the heart to provide sufficient blood flow throughout the body
agonists, TNF inhibitors, calcium channel blockers (especially verapamil and diltiazem), salbutamol, and tamsulosin. By inhibiting the formation of prostaglandins
Heart_failure
Indian multinational pharmaceutical company
Retrieved 18 November 2025. "Alembic Pharma shares gain 2% on USFDA nod for Diltiazem Hydrochloride tablets". Money Control. "Alembic gets FDA nod for angina
Alembic_Pharmaceuticals
CNS depressant medication
Sornidipine Teludipine Tiamdipine Trombodipine Vatanidipine; Diltiazem derivatives: Clentiazem Diltiazem Iprotiazem Nictiazem Siratiazem; Phenylalkylamines: Anipamil
Phenibut
Pharmaceutical compound
Sornidipine Teludipine Tiamdipine Trombodipine Vatanidipine; Diltiazem derivatives: Clentiazem Diltiazem Iprotiazem Nictiazem Siratiazem; Phenylalkylamines: Anipamil
VSN16R
Chemical compound
"Coadministration of grapefruit juice increases systemic exposure of diltiazem in healthy volunteers". European Journal of Clinical Pharmacology. 58
Bergamottin
Several medications which disrupt the movement of Na+ ions
Sornidipine Teludipine Tiamdipine Trombodipine Vatanidipine; Diltiazem derivatives: Clentiazem Diltiazem Iprotiazem Nictiazem Siratiazem; Phenylalkylamines: Anipamil
Sodium_channel_blocker
Antiarrhythmic medication
Sornidipine Teludipine Tiamdipine Trombodipine Vatanidipine; Diltiazem derivatives: Clentiazem Diltiazem Iprotiazem Nictiazem Siratiazem; Phenylalkylamines: Anipamil
Amiodarone
Pharmaceutical compound
Sornidipine Teludipine Tiamdipine Trombodipine Vatanidipine; Diltiazem derivatives: Clentiazem Diltiazem Iprotiazem Nictiazem Siratiazem; Phenylalkylamines: Anipamil
Finasteride/latanoprost/minoxidil
Finasteride/latanoprost/minoxidil
Pore-forming membrane protein
Sornidipine Teludipine Tiamdipine Trombodipine Vatanidipine; Diltiazem derivatives: Clentiazem Diltiazem Iprotiazem Nictiazem Siratiazem; Phenylalkylamines: Anipamil
Ion_channel
Cholesterol-lowering medication
reactions. This is less likely to happen with other CYP3A4 inhibitors such as diltiazem, erythromycin, fluconazole, ketoconazole, clarithromycin, cyclosporine
Atorvastatin
Class of medication used to treat high blood pressure
Sornidipine Teludipine Tiamdipine Trombodipine Vatanidipine; Diltiazem derivatives: Clentiazem Diltiazem Iprotiazem Nictiazem Siratiazem; Phenylalkylamines: Anipamil
Dihydropyridine calcium channel blockers
Dihydropyridine_calcium_channel_blockers
Chemical compound
Sornidipine Teludipine Tiamdipine Trombodipine Vatanidipine; Diltiazem derivatives: Clentiazem Diltiazem Iprotiazem Nictiazem Siratiazem; Phenylalkylamines: Anipamil
Mefenamic_acid
Sterol biosynthesized by all animal cells
Sornidipine Teludipine Tiamdipine Trombodipine Vatanidipine; Diltiazem derivatives: Clentiazem Diltiazem Iprotiazem Nictiazem Siratiazem; Phenylalkylamines: Anipamil
Cholesterol
Benzodiazepine medication
Sornidipine Teludipine Tiamdipine Trombodipine Vatanidipine; Diltiazem derivatives: Clentiazem Diltiazem Iprotiazem Nictiazem Siratiazem; Phenylalkylamines: Anipamil
Lorazepam
Local anaesthetic drug
Sornidipine Teludipine Tiamdipine Trombodipine Vatanidipine; Diltiazem derivatives: Clentiazem Diltiazem Iprotiazem Nictiazem Siratiazem; Phenylalkylamines: Anipamil
Benzocaine
Anticonvulsant medication
Sornidipine Teludipine Tiamdipine Trombodipine Vatanidipine; Diltiazem derivatives: Clentiazem Diltiazem Iprotiazem Nictiazem Siratiazem; Phenylalkylamines: Anipamil
Carbamazepine
Drug for chronic pain
Sornidipine Teludipine Tiamdipine Trombodipine Vatanidipine; Diltiazem derivatives: Clentiazem Diltiazem Iprotiazem Nictiazem Siratiazem; Phenylalkylamines: Anipamil
Crisugabalin
Substance used to diagnose, cure, treat, or prevent disease
channel blockers Relax blood vessels and reduce blood pressure Amlodipine, diltiazem, nicardipine, clevidipine ACE Inhibitors Lower blood pressure by inhibiting
Medication
Enlargement of the heart muscle
heart failure is present (at which time a diuretic is most beneficial). Diltiazem generally produces no demonstrable benefit. Atenolol is commonly administered
Hypertrophic_cardiomyopathy
Calcium channel blocker medication
Sornidipine Teludipine Tiamdipine Trombodipine Vatanidipine; Diltiazem derivatives: Clentiazem Diltiazem Iprotiazem Nictiazem Siratiazem; Phenylalkylamines: Anipamil
Nifedipine
Neurological disorder featuring involuntary, repetitive body movements
progabide, sodium valproate, gaboxadol, or calcium channel blockers (e.g. diltiazem). Tardive dyskinesia most commonly occurs in people with psychiatric conditions
Tardive_dyskinesia
Sedating antidepressant
Sornidipine Teludipine Tiamdipine Trombodipine Vatanidipine; Diltiazem derivatives: Clentiazem Diltiazem Iprotiazem Nictiazem Siratiazem; Phenylalkylamines: Anipamil
Doxepin
Class of prescription drugs in India
HYDROCHLORIDE 151. DIDANOSINE 152. DIGOXINE 153. DILAZEP HYDROCHLORIDE 154. DILTIAZEM 155. DINOPROSTONE 156. DIPHENOXYLATE, ITS SALTS 157. DIPIVEFRIN HYDROCHLORIDE
Schedule_H
Antidepressant medication
Sornidipine Teludipine Tiamdipine Trombodipine Vatanidipine; Diltiazem derivatives: Clentiazem Diltiazem Iprotiazem Nictiazem Siratiazem; Phenylalkylamines: Anipamil
Nortriptyline
Medication used to treat tuberculosis
Sornidipine Teludipine Tiamdipine Trombodipine Vatanidipine; Diltiazem derivatives: Clentiazem Diltiazem Iprotiazem Nictiazem Siratiazem; Phenylalkylamines: Anipamil
Bedaquiline
Tricyclic antidepressant
Sornidipine Teludipine Tiamdipine Trombodipine Vatanidipine; Diltiazem derivatives: Clentiazem Diltiazem Iprotiazem Nictiazem Siratiazem; Phenylalkylamines: Anipamil
Amitriptyline
Abandoned drug
Sornidipine Teludipine Tiamdipine Trombodipine Vatanidipine; Diltiazem derivatives: Clentiazem Diltiazem Iprotiazem Nictiazem Siratiazem; Phenylalkylamines: Anipamil
JJC8-016
DILTIAZEM
DILTIAZEM
DILTIAZEM
DILTIAZEM
DILTIAZEM
DILTIAZEM
DILTIAZEM
DILTIAZEM
DILTIAZEM
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