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Antifungal chemical compound
Ketoconazole, sold under the brand name Nizoral, among others, is an antiandrogen, antifungal, and antiglucocorticoid medication used to treat a number
Ketoconazole
Skin condition of the scalp
symptoms. There is no known cure for dandruff. Antifungal cream, such as ketoconazole, or the keratolytic agent salicylic acid may be used to try to improve
Dandruff
Skin disease
treatment to ketoconazole, as it suppresses growth of the yeast Malassezia furfur. Initial results show similar efficacy to ketoconazole with a relative
Tinea_versicolor
Skin disease
Specifically, ketoconazole or ciclopirox are effective. Seborrhoeic dermatitis of the scalp is often treated with shampoo preparations of ketoconazole, zinc pyrithione
Seborrhoeic_dermatitis
Class of pharmaceutical drugs
antagonists such as mifepristone and synthesis inhibitors such as metyrapone, ketoconazole, and aminoglutethimide. They are used to treat Cushing's syndrome. These
Antiglucocorticoid
Crusting or scaling of a baby's scalp
irritation. A doctor may instead prescribe an antifungal soap such as ketoconazole (2%) shampoo, which can work in a single treatment and shows significantly
Cradle_cap
Antifungal medication
brand names worldwide. In 2007, it was investigated as an alternative to ketoconazole for seborrhoeic dermatitis, as it suppresses growth of the yeast Malassezia
Ciclopirox
Antihistamine medication
vision). Substances that act as inhibitors of the CYP3A4 enzyme such as ketoconazole, erythromycin, cimetidine, and furanocoumarin derivatives (found in grapefruit)
Loratadine
Chemical compound
2021. Levoketoconazole is the levorotatory or (2S,4R) enantiomer of ketoconazole, and it is an inhibitor of the enzymes CYP11B1 (11β-hydroxylase), CYP17A1
Levoketoconazole
and seborrhoeic dermatitis. Combinations of finasteride, minoxidil and ketoconazole are more effective than individual use. Combination therapy of LLLT or
Management_of_hair_loss
Pharmaceutical fungicide or fungistatic used to treat and prevent mycosis
common route to handle a fungal infection. An example is the use of ketoconazole to treat coccidioidomycosis. Like the oral route, this will reach the
Antifungal
Chemical compound
structure and properties are similar to other azole fungicides such as ketoconazole, clotrimazole and miconazole. It is most commonly found as an active
Climbazole
Fungus infection of the skin
include topical agents such as miconazole, terbinafine, clotrimazole, ketoconazole, or tolnaftate applied twice daily until symptoms resolve — usually within
Dermatophytosis
Steroid medication
therefore reduce its effectiveness. Conversely, CYP3A4 inhibitors, such as ketoconazole and itraconazole, can increase its concentrations in the body and the
Triamcinolone
Medication for treating fungal infections
Common examples of azole antifungals include clotrimazole, econazole, ketoconazole, miconazole, and tioconazole. The only polyene antifungal available topically
Topical_antifungal
Belgian pharmaceutical company
substance: miconazole) Nizoral (against dandruff, Active substance: ketoconazole) Duragesic (fentanyl patch for pain suppression. Active substance: fentanyl)
Janssen_Pharmaceuticals
Class of pharmaceutical drugs
used. The earlier androgen synthesis inhibitors aminoglutethimide and ketoconazole have only limitedly been used in the treatment of prostate cancer due
Antiandrogen
Chemical compound
of ketoconazole, is FDA approved to treat Cushing's and carries a lower risk of hepatoxicity and other serious side effects compared to ketoconazole. Metyrapone
Metyrapone
Mixture of selenium sulfides
people with moderate to severe dandruff and compared treatment with 2% ketoconazole shampoo (n=97), 2.5% selenium disulfide shampoo (n=100), and placebo
Selenium_disulfide
Glucocorticoid medication
shown to interact with strong CYP3A4 inhibitors such as ritonavir and ketoconazole. Coadministration of ritonavir and fluticasone may lead to increased
Fluticasone_propionate
Stomach acid suppressing medication
or as a PPI. PPIs reduce absorption of antifungals (itraconazole and ketoconazole) and possibly increase digoxin in plasma Increases plasma concentrations
Lansoprazole
Chemical compound
ergosterol. In addition to its antifungal actions, miconazole, similarly to ketoconazole, is known to act as an antagonist of the glucocorticoid receptor. Miconazole
Miconazole
Chemical compound
result of an interaction with other medications such as erythromycin and ketoconazole, or foods such as grapefruit. The addition of, or a dosage increase in
Terfenadine
Chemical compound
trisulfide Domperidone E-4031 Ergtoxins Erythromycin Gigactonine Haloperidol Ketoconazole Norpropoxyphene Orphenadrine Pimozide PNU-282,987 Promethazine Quinidine
Meclizine
Fungal infection of the skin
required. The over-the-counter options include tolnaftate, as well as ketoconazole (available as Nizoral shampoo that can be applied topically).[citation
Tinea_corporis
Pharmaceutical compound
(cetrimide) Ciclopirox olamine (ciclopirox) Climbazole Clotrimazole Ketoconazole Miconazole Piroctone olamine Selenium disulfide (selenium sulfide) Xenysalate
Suvomipic
Peripheral D2 receptor antagonist
immature blood–brain barrier. In healthy volunteers, the CYP3A4 inhibitor ketoconazole increased the Cmax and AUC concentrations of domperidone by 3- to 10-fold
Domperidone
Chemical compound
Apalutamide Bicalutamide Cimetidine Darolutamide Enzalutamide Flutamide Ketoconazole Nilutamide Seviteronel† Topilutamide (fluridil) Steroidogenesis inhibitors
Chlorodehydromethyltestosterone
Chlorodehydromethyltestosterone
Antihistamine medication
(11–12%) with an elimination half-life of 14 hours. Taking erythromycin or ketoconazole while taking fexofenadine does increase the plasma levels of fexofenadine
Fexofenadine
Liver damage caused by a drug or chemical
ranging everywhere from asymptomatic to fatal. Oral use of the antifungal ketoconazole has been associated with hepatic toxicity, including some fatalities;
Hepatotoxicity
Atypical antipsychotic medication
ketoconazole, clarithromycin, ritonavir, and voriconazole) possibly leading to more side effects. This has been clinically verified for ketoconazole,
Lurasidone
Triazolobenzodiazepine sleep medication
appropriate management strategy for elderly persons with chronic insomnia. Ketoconazole and itraconazole have a profound effect on the pharmacokinetics of triazolam
Triazolam
Drug class
cleavage enzyme (P450scc, CYP11A1) inhibitors such as aminoglutethimide, ketoconazole, and mitotane inhibit the production of pregnenolone from cholesterol
Steroidogenesis_inhibitor
Antibiotic for treatment of tuberculosis
serum levels of ketoconazole after long-term treatment. This is seen with the simultaneous use of rifampin, isoniazid, and ketoconazole. Isoniazid is a
Isoniazid
Medication to treat gastroesophageal reflux disease and other conditions
other PPIs. Drugs that depend on an acidic stomach environment (such as ketoconazole or atazanavir) may be poorly absorbed, whereas acid-labile antibiotics
Omeprazole
Chemical compound
typically exploit to facilitate their own replication within the host cell. Ketoconazole, another antifungal agent used in shampoos Piroctone olamine, another
Zinc_pyrithione
Antiandrogen medication
below increases in midazolam exposure with potent CYP3A4 inhibitors like ketoconazole (+1500%), itraconazole (+1000%), and erythromycin (+350%), and is considered
Bicalutamide
Medication of the calcium channel blocker type
available per dose, include cimetidine, erythromycin, itraconazole, ketoconazole, HIV protease inhibitors, and grapefruit juice. CYP3A4 activators, which
Felodipine
Species of fungus
treatment, such as the use of terbinafine, itraconazole, voriconazole, and ketoconazole, is often effective. E. floccosum is one of the 2 species in the genus
Epidermophyton_floccosum
Changes to heartbeat caused by a drug
Cisapride Domperidone Famotidine Foscarnet Hydroxychloroquine Ibogaine Ketoconazole Methadone Octreotide Ondansetron Oxycodone Tramadol Tacrolimus Tamoxifen
Drug-induced_QT_prolongation
Medication for skin
Synthesis modifiers Acetoxolone Aminoglutethimide Carbenoxolone Enoxolone Ketoconazole Metyrapone Mitotane Osilodrostat Trilostane #WHO-EM ‡Withdrawn from market
Topical_steroid
Chemical compound
When administered concomitantly with drugs that inhibit CYP3A4, such as ketoconazole, the metabolism of solifenacin is impaired, leading to an increase in
Solifenacin
Species of fungus
specific conditions. Topical application of antifungal medications such as ketoconazole, cyclopirox olamine, piroctone olamine, zinc pyrithione, or sulfur compounds
Malassezia_furfur
Topics referred to by the same term
or keto group, the functional group in the chemical compounds ketones Ketoconazole, a medication with antifungal and testosterone-inhibiting properties
Keto
Class of steroid hormones
Aglepristone Ketoconazole Mifepristone Ulipristal acetate Synthesis modifiers Acetoxolone Aminoglutethimide Carbenoxolone Enoxolone Ketoconazole Metyrapone
Corticosteroid
Antiandrogen medication
Apalutamide Bicalutamide Cimetidine Darolutamide Enzalutamide Flutamide Ketoconazole Nilutamide Seviteronel† Topilutamide (fluridil) Steroidogenesis inhibitors
Finasteride
Antifungal medication
antifungal medication. It differs from earlier azole antifungals (such as ketoconazole) in that its structure contains a triazole ring instead of an imidazole
Fluconazole
Group of drugs used against malaria
Troglitazone Troleandomycin Tropanyl 3,5-dimethulbenzoate Zafirlukast Zeranol Antagonists: Ketoconazole Sesamin See also Receptor/signaling modulators
Artemisinin
Chemical compound
Apalutamide Bicalutamide Cimetidine Darolutamide Enzalutamide Flutamide Ketoconazole Nilutamide Seviteronel† Topilutamide (fluridil) Steroidogenesis inhibitors
Mesterolone
Antiviral medication used against herpes, chickenpox, and shingles
associated with superficial punctate keratitis or allergic reactions. Ketoconazole: In-vitro replication studies have found a synergistic, dose-dependent
Aciclovir
Skin condition
Sticky skin can be caused by the chemotherapy medications doxorubicin and ketoconazole. List of syndromes Hall, John (2014). Skin diseases in the immunocompromised
Sticky_skin_syndrome
Corticosteroid medication
required to achieve desired effect of methylprednisolone. Troleandomycin, ketoconazole, and Clarithromycin inhibit metabolism; and may decrease the rate of
Methylprednisolone
Class of lipids
phospholipid chains with surfactant properties. The ethosomal formulation of ketoconazole using phospholipids is a promising option for transdermal delivery in
Phospholipid
Enlargement of the human male breast
good evidence for association with gynecomastia include cimetidine, ketoconazole, gonadotropin-releasing hormone analogues, human growth hormone, human
Gynecomastia
Corticosteroid medication
Concomitant use of prednisolone and strong CYP3A4 inhibitors such as ketoconazole is shown to cause a rise in plasma prednisolone concentrations by about
Prednisolone
Type of corticosteroid medication
liver by the enzyme CYP3A4. Drugs that are CYP3A4 inhibitors such as ketoconazole, clarithromycin, ritonavir, and nefazodone, among many others, may inhibit
Budesonide
Fungal infection
expensive form of treatment compared to azoles (clotrimazole, econazole, ketoconazole, oxiconazole, sulconazole). If the symptoms have been present for long
Tinea_cruris
Medical condition
Aglepristone Ketoconazole Mifepristone Ulipristal acetate Synthesis modifiers Acetoxolone Aminoglutethimide Carbenoxolone Enoxolone Ketoconazole Metyrapone
Steroid_dementia_syndrome
Antipsychotic medication
(CYP3A4). Medications that induce (e.g. carbamazepine) or inhibit (e.g. ketoconazole) CYP3A4 have been shown to decrease and increase, respectively, blood
Ziprasidone
Any steroid hormone that promotes male characteristics
Apalutamide Bicalutamide Cimetidine Darolutamide Enzalutamide Flutamide Ketoconazole Nilutamide Seviteronel† Topilutamide (fluridil) Steroidogenesis inhibitors
Androgen
Chemical compound
not be administered concurrently with strong CYP3A4 inhibitors such as ketoconazole, itraconazole, clarithromycin, atazanavir, nefazodone, saquinavir, telithromycin
Abiraterone_acetate
Chemotherapy medication
taking phenytoin and phenobarbital, common anticonvulsants. Erythromycin, ketoconazole and cyclosporine are CYP3A4 inhibitors and therefore inhibit the metabolic
Docetaxel
Androgen and anabolic steroid
Apalutamide Bicalutamide Cimetidine Darolutamide Enzalutamide Flutamide Ketoconazole Nilutamide Seviteronel† Topilutamide (fluridil) Steroidogenesis inhibitors
Oxandrolone
Medication used to treat insomnia
suvorexant. Combination of suvorexant with the strong CYP3A4 inhibitor ketoconazole increased suvorexant overall exposure by 2.79-fold and peak levels by
Suvorexant
Chemical compound
Aglepristone Ketoconazole Mifepristone Ulipristal acetate Synthesis modifiers Acetoxolone Aminoglutethimide Carbenoxolone Enoxolone Ketoconazole Metyrapone
Clobetasol
Benzodiazepine medication
cimetidine, erythromycin, norfluoxetine, fluvoxamine, itraconazole, ketoconazole, nefazodone, propoxyphene, and ritonavir delay the hepatic clearance
Alprazolam
Chemical compound
Aglepristone Ketoconazole Mifepristone Ulipristal acetate Synthesis modifiers Acetoxolone Aminoglutethimide Carbenoxolone Enoxolone Ketoconazole Metyrapone
Hydrocortisone_cypionate
Hormonal treatment for prostate cancer
Apalutamide Bicalutamide Cimetidine Darolutamide Enzalutamide Flutamide Ketoconazole Nilutamide Seviteronel† Topilutamide (fluridil) Steroidogenesis inhibitors
Androgen_deprivation_therapy
Group of stereoisomers
superseded by newer agents with better efficacy and lower toxicity such as ketoconazole, abiraterone acetate, and other aromatase inhibitors. It remains marketed
Aminoglutethimide
Medication and insecticide
Troglitazone Troleandomycin Tropanyl 3,5-dimethulbenzoate Zafirlukast Zeranol Antagonists: Ketoconazole Sesamin See also Receptor/signaling modulators
Permethrin
Antidepressant medication
such as clarithromycin, erythromycin, fluvoxamine, grapefruit juice, ketoconazole, and ritonavir may lead to increased concentrations of trazodone and
Trazodone
Serotonin modulator antidepressant
been identified for vortioxetine with the cytochrome P450 inhibitors ketoconazole and fluconazole. Rifampicin, a strong and broad cytochrome P450 inducer
Vortioxetine
Benzodiazepine sedative
dependence. Cimetidine, omeprazole, oxcarbazepine, ticlopidine, topiramate, ketoconazole, itraconazole, disulfiram, fluvoxamine, isoniazid, erythromycin, probenecid
Diazepam
Study of the hair and scalp
Antiandrogen or 5α-Reductase inhibitor’s Dutasteride, Finasteride Antifungal Ketoconazole Antihypertensive Minoxidil International Association of Trichologists
Trichology
Medical condition
contains selenium sulfide, over the skin. Topical antifungal azoles such as ketoconazole, itraconazole, and miconazole may also be used. Azoles are generally
Tinea_nigra
Lipid-lowering medication
Troglitazone Troleandomycin Tropanyl 3,5-dimethulbenzoate Zafirlukast Zeranol Antagonists: Ketoconazole Sesamin See also Receptor/signaling modulators
Simvastatin
Oral cough medication
trisulfide Domperidone E-4031 Ergtoxins Erythromycin Gigactonine Haloperidol Ketoconazole Norpropoxyphene Orphenadrine Pimozide PNU-282,987 Promethazine Quinidine
Benzonatate
Drug class
antiandrogens. Examples of CYP17A1 inhibitors include the older drug ketoconazole and the newer drugs abiraterone acetate, orteronel, galeterone, and seviteronel
CYP17A1_inhibitor
Pharmaceutical compound
Etoperidone Flesinoxan Fluanisone Flibanserin Fluprazine Itraconazole Ketoconazole Levodropropizine Lorpiprazole mCPP Mefway MeOPP Mepiprazole Naftopidil
Lu_38-012
Antihypertensive drug of the calcium channel blocker class
by the liver enzyme CYP3A4. In a study, the strong CYP3A4 inhibitor ketoconazole increased the maximal blood plasma concentrations of lercanidipine by
Lercanidipine
Statin medication
levels or activity of endogenous steroid hormones, e.g., cimetidine, ketoconazole, and spironolactone Additional medications for high cholesterol such
Rosuvastatin
Class of heterocyclic compounds
agents with acceptable toxicity profiles led first to the discovery of ketoconazole, the first azole-based oral treatment of systemic fungal infections,
Azole
Pharmaceutical drug classification
Econazole G01AF06 Ornidazole G01AF07 Isoconazole G01AF08 Tioconazole G01AF11 Ketoconazole G01AF12 Fenticonazole G01AF13 Azanidazole G01AF14 Propenidazole G01AF15
ATC_code_G01
Hair care product
specifically for those who have dandruff. These contain fungicides such as ketoconazole, zinc pyrithione and selenium disulfide, which reduce loose dander by
Shampoo
Antibiotic derived from Penicillin
Troglitazone Troleandomycin Tropanyl 3,5-dimethulbenzoate Zafirlukast Zeranol Antagonists: Ketoconazole Sesamin See also Receptor/signaling modulators
Flucloxacillin
Chemical compound
Troglitazone Troleandomycin Tropanyl 3,5-dimethulbenzoate Zafirlukast Zeranol Antagonists: Ketoconazole Sesamin See also Receptor/signaling modulators
Lovastatin
Chemical compound
Apalutamide Bicalutamide Cimetidine Darolutamide Enzalutamide Flutamide Ketoconazole Nilutamide Seviteronel† Topilutamide (fluridil) Steroidogenesis inhibitors
Trenbolone_enanthate
Pharmaceutical compound
Etoperidone Flesinoxan Fluanisone Flibanserin Fluprazine Itraconazole Ketoconazole Levodropropizine Lorpiprazole mCPP Mefway MeOPP Mepiprazole Naftopidil
VCU-1012
Fungal infection
only available treatment, but alternatives, including itraconazole and ketoconazole, became available for milder disease. Fluconazole is the preferred medication
Coccidioidomycosis
Antiandrogen with a nonsteroidal chemical structure
a rare side effect. Nonsteroidal androgen synthesis inhibitors like ketoconazole can also be described as "NSAAs", although the term is usually reserved
Nonsteroidal_antiandrogen
Chemical compound
(cetrimide) Ciclopirox olamine (ciclopirox) Climbazole Clotrimazole Ketoconazole Miconazole Piroctone olamine Selenium disulfide (selenium sulfide) Xenysalate
Afamelanotide
Species of fungus
acid are effective. For more severe or complicated infections, oral ketoconazole was historically shown to be an effective treatment for T. rubrum infections
Trichophyton_rubrum
Medical condition
persistence in the nail for months after discontinuation of therapy. Ketoconazole by mouth is not recommended due to side effects. Oral terbinafine is
Onychomycosis
Hypnotic medication
Phenytoin and carbamazepine may also provoke similar interactions. Ketoconazole and sulfaphenazole interfere with the metabolism of zopiclone. Nefazodone
Zopiclone
Medicinal chemical compound, steroid
Aglepristone Ketoconazole Mifepristone Ulipristal acetate Synthesis modifiers Acetoxolone Aminoglutethimide Carbenoxolone Enoxolone Ketoconazole Metyrapone
Triamcinolone_acetonide
Antibiotic medication
Troglitazone Troleandomycin Tropanyl 3,5-dimethulbenzoate Zafirlukast Zeranol Antagonists: Ketoconazole Sesamin See also Receptor/signaling modulators
Rifaximin
Apalutamide Bicalutamide Cimetidine Darolutamide Enzalutamide Flutamide Ketoconazole Nilutamide Seviteronel† Topilutamide (fluridil) Steroidogenesis inhibitors
Discovery and development of 5α-reductase inhibitors
Discovery_and_development_of_5α-reductase_inhibitors
Apalutamide Bicalutamide Cimetidine Darolutamide Enzalutamide Flutamide Ketoconazole Nilutamide Seviteronel† Topilutamide (fluridil) Steroidogenesis inhibitors
List of 5α-reductase inhibitors
List_of_5α-reductase_inhibitors
Hormone therapy used to treat symptoms of menopause
Apalutamide Bicalutamide Cimetidine Darolutamide Enzalutamide Flutamide Ketoconazole Nilutamide Seviteronel† Topilutamide (fluridil) Steroidogenesis inhibitors
Hormone_replacement_therapy
Antiarrhythmic medication
drugs that inhibit CYP3A4, such as erythromycin, clarithromycin, or ketoconazole, resulting in higher and potentially toxic levels of dofetilide. A steady-state
Dofetilide
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