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Enlarged B cell in the germinal center of lymphoid follicles
In immunology, a centroblast generally refers to an activated B cell that is enlarged (12–18 micrometer) and is rapidly proliferating in the germinal
Centroblast
Lymphatic tissue structure
cellular division, B cells of the germinal center's dark zone are known as centroblasts. Once these B cells have stopped proliferating in the dark zone and moved
Germinal_center
Cancer originating in lymph nodes
uncontrolled division of specific types of B-cells (centrocytes and centroblasts). These cells normally occupy the follicles (nodular swirls of various
Follicular_lymphoma
B cell with a cleaved nucleus derived from centroblasts
centroblasts, and although they are relatively similar in size, centrocytes lack distinct nucleoli and are more irregularly shaped than centroblasts.
Centrocyte
Hematologic cancer that affects lymphocytes
"cleaved" [cleft] cells (centrocytes) mixed with large activated cells (centroblasts), usually nodular ("follicular") growth pattern CD10, surface Ig About
Lymphoma
Type of blood cancer
in a diffuse pattern, efface the tissues' architecture, and resemble Centroblast cells (80% of cases), Immunoblast cells (8–10% of cases), or anaplastic
Diffuse_large_B-cell_lymphoma
cases, immunoblasts show some morphologic features of plasma cells. Centroblasts are distinguished from immunoblasts by being large lymphoid cells containing
Immunoblast
Medical condition
in which certain lymphocyte types, the B-cell-derived centrocytes and centroblasts, form lymph node follicle-like structures principally in the duodenum
Duodenal-type follicular lymphoma
Duodenal-type_follicular_lymphoma
Accessory cell of the mammalian immune system
medium size with angulated, elongated, cleaved, or twisted nuclei. - Centroblasts are larger cells containing vesicular nuclei with one to three basophilic
Dendritic_cell
Immune cells found in lymph nodes
medium size with angulated, elongated, cleaved, or twisted nuclei. - Centroblasts are larger cells containing vesicular nuclei with one to three basophilic
Follicular_dendritic_cells
Protein
(2002). "An unusual Fc receptor-related protein expressed in human centroblasts". Proc. Natl. Acad. Sci. U.S.A. 99 (6): 3776–81. Bibcode:2002PNAS...99
FCRLA
Medical condition
represent <10% of the cells in these lesions and bear resemblances to centroblast, immunoblasts, and/or the Reed–Sternberg cells found in Hodgkin disease
T cell/histiocyte-rich large B-cell lymphoma
T_cell/histiocyte-rich_large_B-cell_lymphoma
Group of lymphomas
morphology of small-to-medium-sized lymphocytes, centrocyte-like B cells, centroblast-like B cells, monocyte-like B cells, plasma cell-like B cells, and/or
Marginal_zone_lymphoma
Medical condition
shows confluent sheets of large malignant B lymphocytes that resemble centroblasts in ~80% of cases or immunoblasts in the remaining ~20% of cases. These
Richter's_transformation
Group of disorders
competent for producing functional antibodies, mature into lymphoblasts, centroblasts, centrocytes, memory B cells, and ultimately plasma cells. During this
Epstein–Barr virus–associated lymphoproliferative diseases
Epstein–Barr_virus–associated_lymphoproliferative_diseases
Medical condition of lymphatic cells
outside its capsule, follicles present throughout the entire node, obvious centroblasts and the absence or diminishing mantle zones. Immunohistochemistry can
Follicular_hyperplasia
Medical condition
dense, diffuse sheets of infiltrating large-sized B-cells that resemble centroblasts and immunoblasts. The infiltrates are located in the dermis and subcutaneous
Primary cutaneous diffuse large B-cell lymphoma, leg type
Primary_cutaneous_diffuse_large_B-cell_lymphoma,_leg_type
Medical condition
and show medium- to large-sized lymphoid tumor B-cells that resemble centroblasts diffusely infiltrating and effacing the architecture of the involved
Primary testicular diffuse large B-cell lymphoma
Primary_testicular_diffuse_large_B-cell_lymphoma
Medical condition
rather than infiltrative, should consist of large cells that resemble centroblasts, immunoblasts, or, less commonly, anaplastic (i.e. poorly differentiated)
Diffuse large B-cell lymphoma associated with chronic inflammation
Diffuse_large_B-cell_lymphoma_associated_with_chronic_inflammation
Medical condition
lymphoblasts mixed with occasional macrophages and rare centrocytes and centroblasts that together form follicular structures that partially or completely
Pediatric-type follicular lymphoma
Pediatric-type_follicular_lymphoma
CENTROBLAST
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Boy/Male
Gujarati, Hindu, Indian, Kannada, Malayalam, Marathi, Sanskrit, Telugu
Blue Lotus
Boy/Male
Gaelic Irish
From South Munster. An Irish surname referring to Munster: (one of ancient Ireland's five regions.).
Girl/Female
British, English, Indian, Sanskrit
Reason; Cause
Boy/Male
Muslim
Eternal or immortal or living forever
Girl/Female
Gaelic American Irish
Raging.
Surname or Lastname
English
English : occupational name for a transporter or server of water, Middle English ewer (Old Northern French evier, Old French aiguier, from Latin aquarius, a derivative of aqua ‘water’). There has been considerable confusion with Ure.
Boy/Male
American, Christian, Danish, English, French, Gujarati, Hindu, Indian
The Sea; Great Sea; Attractive
Boy/Male
British, English
Golden Friend
Girl/Female
Greek
From the woods.
Boy/Male
German
Noble leader.
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