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Type of white blood cell
Macrophages (/ˈmækroʊfeɪdʒ/; abbreviated Mφ, MΦ or MP) are a type of white blood cell of the innate immune system that engulf and digest pathogens, such
Macrophage
The terms "macrophage" and "microphage" are used in ecology to describe heterotrophs that consume food in two different ways. Both macrophages and microphages
Macrophage_(ecology)
Mammalian protein found in Homo sapiens
Granulocyte-macrophage colony-stimulating factor (GM-CSF), also known as colony-stimulating factor 2 (CSF2), is a monomeric glycoprotein secreted by macrophages,
Granulocyte-macrophage colony-stimulating factor
Granulocyte-macrophage_colony-stimulating_factor
Bone-marrow-derived macrophage (BMDM) refers to macrophage cells that are generated in a research laboratory from mammalian bone marrow cells. BMDMs can
Bone marrow-derived macrophage
Bone_marrow-derived_macrophage
Biological process
Macrophage polarization is a process by which macrophages adopt different functional programs in response to the signals from their microenvironment.
Macrophage_polarization
Alveolar macrophages whose characteristics have been affected by smoking
Smoker's macrophages are alveolar macrophages whose characteristics, including appearance, cellularity, phenotypes, immune response, and other functions
Smoker's_macrophages
Mammalian protein found in humans
known as macrophage colony-stimulating factor (M-CSF), is a secreted cytokine which causes hematopoietic stem cells to differentiate into macrophages or other
Macrophage colony-stimulating factor
Macrophage_colony-stimulating_factor
Medical condition
Macrophage activation syndrome is a severe, potentially life-threatening, complication of several chronic rheumatic diseases of childhood. It occurs most
Macrophage activation syndrome
Macrophage_activation_syndrome
Protein-coding gene in the species Homo sapiens
Macrophage mannose receptor 1, also known as mannose receptor C-type 1, is a protein that in humans is encoded by the MRC1 gene. The recognition of complex
Macrophage_mannose_receptor_1
Macrophage subset
Regulatory macrophages (Mregs) represent a subset of anti-inflammatory macrophages. In general, macrophages are a very dynamic and plastic cell type and
Regulatory_macrophages
Protein-coding gene in the species Homo sapiens
Macrophage migration inhibitory factor (MIF), also known as glycosylation-inhibiting factor (GIF), L-dopachrome isomerase, or phenylpyruvate tautomerase
Macrophage migration inhibitory factor
Macrophage_migration_inhibitory_factor
Protein family
Macrophage Inflammatory Proteins (MIP) belong to the family of chemotactic cytokines known as chemokines. In humans, there are two major forms, MIP-1α
Macrophage inflammatory protein
Macrophage_inflammatory_protein
Protein produced by artificial modification of vitamin D-binding protein
GcMAF (or Gc protein-derived macrophage activating factor) is a protein produced by modification of vitamin D-binding protein. It has been falsely promoted
GcMAF
Skin macrophages used for wound repair and hair growth
Dermal macrophages are macrophages in the skin that facilitate skin homeostasis by mediating wound repair, hair growth, and salt balance. Their functional
Dermal_macrophage
Protein-coding gene in humans
AIM, for apoptosis inhibitor of macrophage) that in humans is encoded by the CD5L gene. It is expressed by macrophages. It regulates immune responses and
CD5L
Type of microphage
A tingible body macrophage (TBM) is a type of macrophage predominantly found in germinal centers of lymph nodes. They contain many phagocytized, apoptotic
Tingible_body_macrophage
Macrophage found in the lungs
An alveolar macrophage, pulmonary macrophage, (or dust cell, or dust eater) is a type of macrophage, a professional phagocyte, found in the airways and
Alveolar_macrophage
Type of macrophage
Tumor-associated macrophages (TAMs) are a class of immune cells present in high numbers in the microenvironment of solid tumors. They are heavily involved
Tumor-associated_macrophage
Cell type
CFU-GM (Colony Forming Unit-Granulocyte/Macrophage), also known as Granulocyte-Monocyte Progenitor (GMP), is a colony forming unit. It is derived from
CFU-GM
Part of the immune system
phagocyte system or mononuclear phagocytic system (MPS), also known as the macrophage system, is a part of the immune system that consists of the phagocytic
Mononuclear_phagocyte_system
Protein-coding gene in humans
granulocyte-macrophage colony-stimulating factor receptor, also known as CD116 (Cluster of Differentiation 116), is a receptor for granulocyte-macrophage colony-stimulating
Granulocyte-macrophage colony-stimulating factor receptor
Granulocyte-macrophage_colony-stimulating_factor_receptor
Mammalian protein found in humans
g., monocytic phagocytes, osteoclasts), by circulating macrophages, and by tissue macrophages (e.g., Kupffer cells, microglia). Human CD68 is a Type I
CD68
Macrophages present in adipose tissue
Adipose tissue macrophages (ATMs) comprise resident macrophages present in adipose tissue. Besides adipocytes, adipose tissue contains the stromal vascular
Adipose_tissue_macrophages
Pathological cells in lung
alveolar macrophages, also known as pulmonary foam cells, are cells found in bronchoalveolar lavage (BAL) specimens that consist of macrophages containing
Lipid-laden alveolar macrophage
Lipid-laden_alveolar_macrophage
Macrophage-1 antigen (or integrin αMβ2 or macrophage integrin or Mac-1) is a complement receptor ("CR3") consisting of CD11b (integrin αM) and CD18 (integrin
Macrophage-1_antigen
A macrophage-activating factor (MAF) is a lymphokine or other receptor based signal that primes macrophages towards cytotoxicity to tumors, cytokine secretion
Macrophage-activating_factor
Cells that ingest harmful matter within the body
particles, bacteria, and dead or dying cells. They include monocytes, macrophages, neutrophils, tissue dendritic cells, and mast cells. Their name comes
Phagocyte
Human retrovirus, cause of AIDS
human immune system, such as helper T cells (specifically CD4+ T cells), macrophages, and dendritic cells. HIV infection leads to low levels of CD4+ T cells
HIV
Protein-coding gene in the species Homo sapiens
Macrophage scavenger receptor 1, also known as MSR1, is a protein which in humans is encoded by the MSR1 gene. MSR1 has also been designated CD204 (cluster
MSR1
Protein-coding gene in the species Homo sapiens
Macrophage-stimulating protein (MSP), also known as hepatocyte growth factor-like protein (HLP, HGFL, or HGFLP), is a protein that in humans is encoded
MST1
Type of tissue in the spleen
dendritic cells and macrophages. Some of the white pulp's macrophages are of a specialized kind known as metallophilic macrophages. The T cell zone (periarteriolar
White_pulp
Mammalian protein found in humans
Chemokine (C-C motif) ligand 3 (CCL3) also known as macrophage inflammatory protein 1-alpha (MIP-1-alpha) is a protein that in humans is encoded by the
CCL3
Enzyme involved in breakdown of extracellular matrix
Matrix metalloproteinase-12 (MMP-12) also known as macrophage metalloelastase (MME) or macrophage elastase (ME) is an enzyme that in humans is encoded
Matrix_metallopeptidase_12
Macrophage elastase (EC 3.4.24.65, metalloelastase, human macrophage metalloelastase (HME), MMP-12) is an enzyme. This enzyme catalyses the following chemical
Macrophage_elastase
Phagocytic white blood cells containing an iron storage compound
A siderophage is a hemosiderin-containing macrophage. Heart failure cells are siderophages generated in the alveoli of the lungs of people with left heart
Siderophage
Macrophages located in the liver
Kupffer cells, also known as stellate macrophages and Kupffer–Browicz cells, are specialized cells localized in the liver within the lumen of the liver
Kupffer_cell
American cell biologist
discovery and characterization of macrophages with anti-inflammatory and growth-promoting activity, termed regulatory macrophages. He has written over 150 articles
David_Mosser
Fat-laden M2 macrophages seen in atherosclerosis
cells, and stem cells, but the most-studied foam cells are derived from macrophages and are found in atheromatous plaques. They contain low density lipoproteins
Foam_cell
Vertebrate cell
system is part of the organism's immune system. The histiocyte is a tissue macrophage or a dendritic cell (histio, diminutive of histo, meaning tissue, and
Histiocyte
Protein-coding gene in the species Homo sapiens
amounts on macrophages of the spleen, liver, lymph node, bone marrow, colon, and lungs. Soluble SIGLEC-1 is a biomarker of monocyte-macrophage activation
Sialoadhesin
Protein found in humans
Colony stimulating factor 1 receptor (CSF1R), also known as macrophage colony-stimulating factor receptor (M-CSFR), and CD115 (Cluster of Differentiation
Colony stimulating factor 1 receptor
Colony_stimulating_factor_1_receptor
Immune cells that responds to any antigen
A non-specific immune cell is an immune cell (such as a macrophage, neutrophil, or dendritic cell) that responds to many antigens, not just one antigen
Nonspecific_immune_cell
Group of innate immune system disorders
which may present as excessive activation of neutrophils, monocytes/macrophages and dendritic cells causing auto-inflammatory symptoms, or T cell and
Autoinflammatory_diseases
Algerian professor (born 1969)
the macrophage and dendritic cell arms of the myeloid lineage, including demonstrating the developmental origins of tissue-resident macrophages and revealing
Miriam_Merad
Australian professor of microbiology, immunologist (1922–2007)
described the life history of the macrophage. He showed that by infecting mice with intracellular bacteria, macrophages could be activated to attack other
George_Mackaness
Series of events that restore integrity to damaged tissue after an injury
restore the epithelial layer. Subdivisions of the cellular phase are: Macrophages and inflammatory components (within 1–2 days) Epithelial-mesenchymal
Wound_healing
Cell membrane engulfing a large particle
as means to obtain nutrients. The two main cells that do this are the Macrophages and the Neutrophils of the immune system. Where phagocytosis is used
Phagocytosis
Inflammatory aggregation of immune cells
A granuloma (pl. granulomata) is an aggregation of macrophages (along with other cells) that forms in response to chronic inflammation. This occurs when
Granuloma
Characteristic cells of granulomatous hypersensitivity
cells (also called epithelioid histiocytes) are derivatives of activated macrophages resembling epithelial cells. Structurally, epithelioid cells (when examined
Epithelioid_cell
Protein-coding gene in the species Homo sapiens
and widely used marker of murine macrophage populations. F4/80 is not necessary for the development of tissue macrophages but is required for the induction
EMR1
Mammalian protein found in humans
that is also known as GRO3 oncogene (GRO3), GRO protein gamma (GROg) and macrophage inflammatory protein-2-beta (MIP2b). CXCL3 controls migration and adhesion
CXCL3
Type of allergic reaction
response. This response involves the interaction of T cells, monocytes, and macrophages. This reaction is caused when CD4+ Th1 cells recognize foreign antigen
Type_IV_hypersensitivity
Cell type in which HIV infects and replicates
such as CD4+ helper T-cells and macrophages that express the CD4 molecule on their surface. HIV-1 entry to macrophages and T helper cells is mediated not
HIV_tropism
Gerlach JT, Behr J, Dörger M (September 1997). "Cell size of alveolar macrophages: an interspecies comparison". Environmental Health Perspectives. 105
List_of_immune_cells
Cell that matures into a monocyte
are the committed progenitor cells that differentiated from a committed macrophage or dendritic cell precursor (MDP) in the process of hematopoiesis. They
Monoblast
Islet resident macrophages are the predominant myeloid cell of the pancreatic islets of langerhans. Islet resident macrophages are uniquely found within
Pancreatic_islet_macrophage
Protein-coding gene in the species Homo sapiens
Macrophage-capping protein (CAPG) also known as actin regulatory protein CAP-G is a protein that in humans is encoded by the CAPG gene. This gene encodes
Macrophage-capping_protein
Macrophage cell of the skin
A Langerhans cell (LC) is a tissue-resident macrophage of the skin once thought to be a resident dendritic cell. These cells contain organelles called
Langerhans_cell
Frequently fatal immune reaction
alveolar macrophages to produce viral nucleic acid, which stimulates the infected cells to release cytokines and chemokines, activating macrophages, dendritic
Cytokine_storm
Medical condition
bacterium is an obligate intracellular pathogen affecting monocytes and macrophages. The most common symptoms are fever, headache, malaise, and muscle aches
Human monocytotropic ehrlichiosis
Human_monocytotropic_ehrlichiosis
psychological distress. It has been argued that depression may be the result of macrophage activity as part of the process of inflammation. Many of the symptoms
Depression and immune function
Depression_and_immune_function
Mammalian protein found in humans
Chemokine (C-C motif) ligands 4 (also CCL4), previously known as macrophage inflammatory protein (MIP-1β), is a protein which in humans is encoded by the
CCL4
Protein-coding gene in the species Homo sapiens
Macrophage receptor with collagenous structure (MARCO) is a protein that in humans is encoded by the MARCO gene. MARCO is a class A scavenger receptor
MARCO
American immunologist
Randolph characterized monocyte differentiation to dendritic cells and macrophages and made advances in our understanding of dendritic cell trafficking
Gwendalyn_J._Randolph
Lipopeptide Toll-like receptor 2 and 6 agonist
Macrophage-activating lipopeptide 2 (MALP-2) is a lipopeptide Toll-like receptor (TLR)-2 and 6 agonist. It is used in immunological research to simulate
Macrophage-activating lipopeptide 2
Macrophage-activating_lipopeptide_2
Biological system protecting an organism against disease
mainly, by cells of the innate immune system, such as dendritic cells, macrophages, monocytes, neutrophils, and epithelial cells, to identify two classes
Immune_system
Glial cell located throughout the brain and spinal cord
for about around 5–10% of cells found within the brain. As the resident macrophage cells, they act as the first and main form of active immune defense in
Microglia
Tumor derived from histiocytes
develop from a class of immune cells called histiocytes, which include macrophages, dendritic cells, and monocytes. Yamada R, Komohara Y (2024). "Histiocytic
Histiocytic_neoplasm
Mammalian protein found in Homo sapiens
release. These receptors were localized on immune cells such as monocytes, macrophages, B-cells, and T-cells. Further investigation into the expression patterns
Cannabinoid_receptor_2
Bodily response to the presence of a foreign object
formation consists of protein adsorption, macrophages, multinucleated foreign body giant cells (macrophage fusion), fibroblasts, and angiogenesis. It
Foreign_body_reaction
Mammalian protein found in humans
The protein encoded by this gene is secreted by dendritic cells and macrophages, and elicits its effects on its target cells by interacting with cell
CCL22
Damage to nervous tissue
that encases nerves. During Wallerian degeneration Schwann cells and macrophages interact to remove debris, specifically myelin and the damaged axon,
Nerve_injury
Immune disorder in the blood leading to hyperinflammation
hyperinflammation caused by uncontrolled proliferation of benign lymphocytes and macrophages that secrete high amounts of inflammatory cytokines. It is classified
Hemophagocytic lymphohistiocytosis
Hemophagocytic_lymphohistiocytosis
Subtype of leukocytes
the largest type of leukocyte in the blood and can differentiate into macrophages and monocyte-derived dendritic cells. As a part of the vertebrate innate
Monocyte
Protein-coding gene in humans
(January 1996). "Molecular cloning and expression of cDNA encoding human macrophage C-type lectin. Its unique carbohydrate binding specificity for Tn antigen"
CLEC10A
Category of small signaling proteins
all nucleated cells, but especially endo/epithelial cells and resident macrophages (many near the interface with the external environment) are potent producers
Cytokine
Connective tissue present within and around synovial joints
contact with the synovial fluid at the tissue surface are many rounded macrophage-like synovial cells (type A) and also type B cells, which are also known
Synovial_membrane
Human monocytic cell line
A. Increased CO2 production on phagocytosis and differentiation into macrophage-like cells Polarization into the M1 phenotype by incubation with IFN-γ
THP-1_cell_line
Class of enzymes
converted to the regulatory protein, Gc Macrophage Activating Factor, a protein involved in the activation of macrophages — in cases when many types of incompatible
Α-N-acetylgalactosaminidase
Protein-coding gene in the species Homo sapiens
matrix disassembly negative regulation of apoptotic process proteolysis macrophage differentiation positive regulation of keratinocyte migration positive
MMP9
Protein family
Macrophage migration inhibitory factor domain is an evolutionary conserved protein domain. Macrophage migration inhibitory factor (MIF) is a key regulatory
Macrophage migration inhibitory factor domain
Macrophage_migration_inhibitory_factor_domain
Protein-coding gene in the species Homo sapiens
protein that in humans is encoded by the TREM2 gene. TREM2 is expressed on macrophages, immature monocyte-derived dendritic cells, osteoclasts, and microglia
TREM2
British pathologist
work on the phenotypic and functional diversity of macrophages. He began his studies on macrophages while in the laboratory of Zanvil Cohn at Rockefeller
Siamon_Gordon
Cellular process
time-lapse microscopy footage characterising the interaction between macrophages and the human fungal pathogen Cryptococcus neoformans. Subsequently,
Vomocytosis
Mammalian protein found in humans
motif) ligand 20 (CCL20) or liver activation regulated chemokine (LARC) or Macrophage Inflammatory Protein-3 (MIP3A) is a small cytokine belonging to the CC
CCL20
Protein-coding gene in humans
Macrophage-stimulating protein receptor is a protein that in humans is encoded by the MST1R gene. MST1R is also known as RON (Recepteur d'Origine Nantais)
MST1R
Mammalian protein found in humans
chain is known as CD74. CD74 is a cell surface receptor for the cytokine macrophage migration inhibitory factor (MIF). The nascent MHC class II protein in
CD74
Abnormal layer of tissue
vessels. Pannus tissue is composed of aggressive macrophage- and fibroblast-like mesenchymal cells, macrophage-like cells and other inflammatory cells that
Pannus
Type of macrophage
erythematosus cell (LE cell), also known as Hargraves cell, is a neutrophil or macrophage that has phagocytosed (engulfed) the denatured nuclear material of another
LE_cell
Part of the spleen
types of macrophages that are unique to this area: the marginal zone macrophages and the marginal metallophilic macrophages. These two macrophage sub-types
Marginal_zone
Aspect of immunity
precipitation of antibody-antigen products, prime for phagocytosis by macrophages and other cells, block viral receptors, and stimulate other immune responses
Humoral_immunity
Macrophages are an important regenerative components of the immune system and their dysfunction can impair tissue repair. Historically, macrophages have
Immune system contribution to regeneration
Immune_system_contribution_to_regeneration
Protein family
Differentiation 206, CD206) is a C-type lectin primarily present on the surface of macrophages, immature dendritic cells and liver sinusoidal endothelial cells, but
Mannose_receptor
Family of proteins
that was found to stimulate formation of colonies of macrophages, for instance, was called macrophage colony-stimulating factor, for granulocytes, granulocyte
Colony-stimulating_factor
Organ of the lymphatic system
plasma cells, as well as macrophages which are present within the medullary sinuses. In case of diseases like cancer, macrophages within the lymph nodes
Lymph_node
Mammalian protein found in humans
of differentiation 14) is a surface membrane protein made mostly by macrophages as part of the innate immune system. It helps to detect bacteria in the
CD14
Spectrum of conditions caused by HIV infection
infects components of the human immune system such as CD4+ T cells, macrophages and dendritic cells. It directly and indirectly destroys CD4+ T cells
HIV/AIDS
Infectious disease
mechanism of the macrophage begins when a foreign body, such as a bacterial cell, binds to receptors on the surface of the macrophage. The macrophage then stretches
Tuberculosis
American microbiologist and public health official (born 1974)
countries. Her dissertation explored how trypanosome GIP-sVSG regulates macrophages during Trypanosoma brucei rhodesiense infection. Monarez was a postdoctoral
Susan_Monarez
Human disease caused by amoeba protists
staining of trophozoites (brown) using specific anti–Entamoeba histolytica macrophage migration inhibitory factor antibodies in a patient with amoebic colitis
Amoebiasis
MACROPHAGE
MACROPHAGE
MACROPHAGE
MACROPHAGE
Male
Italian
Pet form of Italian Angiolo, ANGIOLETTO means "angel, messenger."
Boy/Male
Tamil
Elavarasan | à®à®²à®¾à®µà®¾à®°à®¾à®¸à®¨
Prince
Girl/Female
British, English
Friend of the Elves
Male
Russian
(Иванн) Russian form of Greek Ioannes, IVANN means "God is gracious."
Boy/Male
Muslim
Connection, Someone who connects
Boy/Male
Hindu, Indian
Light; Splendour
Girl/Female
Hindu, Indian
Black Beauty
Boy/Male
Muslim/Islamic
Merciful kind
Male
Hindi/Indian
Variant form of Hindi Vasu, BASU means "dweller."
Boy/Male
Muslim
Name of a prophet of almighty, A prophet title of the 11th
MACROPHAGE
MACROPHAGE
MACROPHAGE
MACROPHAGE
MACROPHAGE