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Protein domain
The tetratricopeptide repeat (TPR) is a structural motif. It consists of a degenerate 34 amino acid tandem repeat identified in a wide variety of proteins
Tetratricopeptide_repeat
Protein-coding gene in the species Homo sapiens
Tetratricopeptide repeat protein 39B is a protein that in humans is encoded by the TTC39B gene. TTC39B is also known as C9orf52 or FLJ33868. The main feature
Tetratricopeptide repeat protein 39B
Tetratricopeptide_repeat_protein_39B
Protein-coding gene in the species Homo sapiens
Tetratricopeptide repeat 39A is a human protein encoded by the TTC39A gene. TTC39A is also known as DEME-6 (differentially expressed in MCF7 with estradiol
Tetratricopeptide_repeat_39A
Protein-coding gene in the species Homo sapiens
Tetratricopeptide repeat protein 39C is a protein that in humans is encoded by the TTC39C gene. TTC39C is one of three TTC39. Its function is currently
Tetratricopeptide repeat protein 39C
Tetratricopeptide_repeat_protein_39C
Protein-coding gene in the species Homo sapiens
Transmembrane and tetratricopeptide repeat containing 1 is a protein that in humans is encoded by the TMTC1 gene. GRCh38: Ensembl release 89: ENSG00000133687
Transmembrane and tetratricopeptide repeat containing 1
Transmembrane_and_tetratricopeptide_repeat_containing_1
Protein-coding human gene
Tetratricopeptide repeat domain 21B is a protein that in humans is encoded by the TTC21B gene. This gene encodes a member of TTC21 family, containing several
Tetratricopeptide repeat domain 21B
Tetratricopeptide_repeat_domain_21B
Protein-coding gene in the species Homo sapiens
Tetratricopeptide repeat domain 16 (TTC16) is an uncharacterized protein that in humans is encoded by the gene TTC16. Another alias for this gene is TPR
Tetratricopeptide repeat protein 16
Tetratricopeptide_repeat_protein_16
Protein-coding gene in the species Homo sapiens
Histone demethylase UTY, or Ubiquitously transcribed tetratricopeptide repeat, Y chromosome, is an enzyme that in humans is encoded by the UTY gene. This
UTY_(gene)
Protein-coding gene in the species Homo sapiens
Tetratricopeptide repeat domain 19, also known as TPR repeat protein 19 or Tetratricopeptide repeat protein 19, mitochondrial is a protein that in humans
TTC19
Pseudogene in the species Homo sapiens
Tetratricopeptide repeat domain 3 pseudogene 1 is a protein that in humans is encoded by the TTC3P1 gene. GeneCards Symbol: TTC3P1 2 Tetratricopeptide
TTC3P1
Protein found in humans
486 Da. SKIC3 contains six tetratricopeptide repeat domains, explaining its previous name "TTC37" (tetratricopeptide repeat domain 37). SKIC3 is a component
Superkiller_complex_protein_3
Protein-coding gene in the species Homo sapiens
Tetratricopeptide repeat domain 7A (TTC7A) is a protein that in humans is encoded by the TTC7A gene. TPR domain-containing proteins, such as TTC7A, have
TTC7A
Protein-coding gene in the species Homo sapiens
Tetratricopeptide repeat and ankyrin repeat containing 1 is a protein that in humans is encoded by the TRANK1 gene. Through a Genome-wide association
TRANK1
Protein family
helix-turn-helix structure similar to those found in the tetratricopeptide repeat. Several repeats of the protein forms a ring around a single-strand RNA
Pentatricopeptide_repeat
Protein-coding gene in humans
Lysine-specific demethylase 6A also known as Ubiquitously transcribed tetratricopeptide repeat, X chromosome (UTX), is a protein which in humans is encoded by
Lysine-specific demethylase 6A
Lysine-specific_demethylase_6A
Protein-coding gene in humans
also called DYX1C1). This protein contains 420 amino acids with 3 tetratricopeptide repeat (TPR) domains, thought to mediate protein–protein interactions
DNAAF4
Protein-coding gene in the species Homo sapiens
Transmembrane and Tetratricopeptide repeat containing 4 is a protein that in humans is encoded by the TMTC4 gene. This protein crosses the plasma membrane
TMTC4
Protein-coding gene in the species Homo sapiens
Tetratricopeptide repeat domain 28 is a protein that in humans is encoded by the TTC28 gene. GRCh38: Ensembl release 89: ENSG00000100154 – Ensembl, May
TTC28
Protein-coding gene in humans
Tetratricopeptide repeat protein 1 is a protein that in humans is encoded by the TTC1 gene. TTC1 has been shown to interact with HSPA4. GRCh38: Ensembl
TTC1
Protein-coding gene in the species Homo sapiens
the ZC3H7B gene. RoXaN is a protein that contains tetratricopeptide repeat and leucine-aspartate repeat as well as zinc finger domains. This protein also
Roxan
Protein-coding gene in the species Homo sapiens
SH3 domain and tetratricopeptide repeats-containing protein 2 is a protein that in humans is encoded by the SH3TC2 gene. It is believed to be expressed
SH3TC2
Protein-coding gene in the species Homo sapiens
Interferon-induced protein with tetratricopeptide repeats 1 is a protein that in humans is encoded by the IFIT1 gene. GRCm38: Ensembl release 89: ENSMUSG00000067297
IFIT1
Small glutamine-rich tetratricopeptide repeat-containing protein alpha is a protein that in humans is encoded by the SGTA gene. SGTA orthologs have also
SGTA
Evolutionary process
evolutionary history of the IFIT (Interferon Induced proteins with Tetratricopeptide repeats) family of antiviral genes has been shaped by continuous interactions
Endogenosymbiosis
Protein-coding gene in the species Homo sapiens
Tetratricopeptide repeat protein 4 is a protein that in humans is encoded by the TTC4 gene. The 34-amino acid tetratricopeptide repeat (TPR) motif is found
TTC4
Protein-coding gene in the species Homo sapiens
Tetratricopeptide repeat protein 35 is a protein that in humans is encoded by the TTC35 gene. GRCh38: Ensembl release 89: ENSG00000104412 – Ensembl, May
TTC35
Human chromosome
mitochondrial TSHB: thyroid stimulating hormone, beta TTC39A: Tetratricopeptide repeat 39A UBR4: E3 ubiquitin-protein ligase component n-recognin 4 UROD:
Chromosome_1
Protein-coding gene in the species Homo sapiens
Tetratricopeptide repeat protein 3 is a protein that in humans is encoded by the TTC3 gene. GRCh38: Ensembl release 89: ENSG00000182670 – Ensembl, May
TTC3
Protein-coding gene in the species Homo sapiens
Tetratricopeptide repeat domain 8 (TTC8) also known as Bardet–Biedl syndrome 8 is a protein that in humans is encoded by the TTC8 gene. TTC8 is associated
TTC8
Polyphyletic group of bacteria
also contain PDZ domains, while several other MM proteins contain tetratricopeptide repeat (TPR) domains. The TPR domains are characterized by a folding consisting
Magnetotactic_bacteria
Human chromosome
TSSK1B: encoding protein Testis specific serine kinase 1b TTC37: Tetratricopeptide repeat domain 37 UPF0488: encodes G protein-coupled receptor protein signaling
Chromosome_5
Protein-coding gene in humans
an FKBP-like domain (FK2), and a C-terminal region with three tetratricopeptide repeat (TPR) motifs. The FK1 domain has PPIase activity, facilitating
FKBP5
Protein-coding gene in the species Homo sapiens
Interferon-induced protein with tetratricopeptide repeats 3, also known as interferon-stimulated gene 49 (ISG49), is a protein that in humans is encoded
IFIT3
Protein-coding gene in the species Homo sapiens
subunit contains 13 tetratricopeptide repeats (TPRs); the 13th repeat is truncated. These subunits are dimerized by TPR repeats 6 and 7. OGT is highly
Protein_O-GlcNAc_transferase
Protein domain
include: EGF repeats, cadherin repeats, leucine-rich repeats, HEAT repeats, ankyrin repeats, armadillo repeats, tetratricopeptide repeats, etc. Whenever
Solenoid_protein_domain
Human chromosome
encoding protein Torsin-2A TSC1: tuberous sclerosis complex 1 TTC39B: tetratricopeptide repeat protein 39B UBAC1: ubiquitin-associated domain containing protein
Chromosome_9
Protein found in humans
WD and tetratricopeptide repeats 1 Identifiers Symbol WDTC1 NCBI gene 23038 HGNC 29175 RefSeq NM_015023 UniProt Q8N5D0 Other data Locus Chr. 1 p35.3 Search
WDTC1
Sex chromosome present in both sexes in the XY and X0 sex-determination systems
Testis-specific Y-encoded-like protein 2 TTC3P1: encoding protein Tetratricopeptide repeat domain 3 pseudogene 1 USP51: encoding enzyme Ubiquitin carboxyl-terminal
X_chromosome
Human chromosome
trafficking kinesin-binding protein 1 TRANK1: encoding protein Tetratricopeptide repeat and ankyrin repeat containing 1 TTLL3: encoding protein Tubulin tyrosine
Chromosome_3
Human chromosome
encoding protein Transmembrane protein 241 TTC39C: encoding protein Tetratricopeptide repeat protein 39C TWSG1: encoding protein Twisted gastrulation protein
Chromosome_18
Protein-coding gene in the species Homo sapiens
including an N-terminal immunophilin-like domain and a C-terminal tetratricopeptide repeat (TPR) domain. The protein encoded by this gene is a member of the
Peptidylprolyl_isomerase_D
Protein pathway in cells
resembles a boomerang with a filled-in concave face and includes three tetratricopeptide repeat (TPR) subdomains. Snf7 binds to a conserved hydrophobic patch on
ESCRT
Topics referred to by the same term
educational company Town Planning Review, Liverpool University Press Tetratricopeptide repeat, a degenerate protein sequence Total peripheral resistance, vascular
TPR
Protein-coding gene in the species Homo sapiens
characterized by some structural features: All homologues have nine tetratricopeptide repeat (TPR) motifs, that are clustered into domains of three TPRs. The
Stress-induced-phosphoprotein 1
Stress-induced-phosphoprotein_1
Human chromosome
potential cation channel subfamily M member 2 TTC3: encoding protein tetratricopeptide repeat domain 3 U2AF1: encoding splicing factor U2AF 35 kDa subunit UBASH3A:
Chromosome_21
Type of proteins that maintain gene expression
remodeling factor-38kD Nurf38 trithorax trx Trithorax like Trl Ubiquitously transcribed tetratricopeptide repeat, X chromosome Utx verthandi vtd zeste z
Trithorax-group_proteins
Human chromosome
mitochondrial tRNA-specific 2-thiouridylase 1 TTC28: encoding protein tetratricopeptide repeat domain 28 TTLL1: encoding enzyme probable tubulin polyglutamylase
Chromosome_22
Protein family
correlate with decreased CFTRΔF508 levels. EMC2 contains three tetratricopeptide repeat domains (TRPs). TRPs have been shown to mediate protein-protein
Endoplasmic reticulum membrane protein complex
Endoplasmic_reticulum_membrane_protein_complex
IFIT proteins (Interferon Induced proteins with tetratricopeptide repeats) are produced in the human body and are supposed to confer immunity against
IFIT_proteins
Human chromosome
domain-containing protein 2 TMTC1: encoding protein Transmembrane and tetratricopeptide repeat containing 1 TMEM117: encoding protein Transmembrane protein 117
Chromosome_12
Heat shock proteins with a molecular mass around 90kDa
is occupied. At the very C-terminal end of the protein is the tetratricopeptide repeat (TPR) motif recognition site, the conserved MEEVD pentapeptide
Hsp90
Protein-coding gene in the species Homo sapiens
(GTP-bound) conformations. It also has the apolipophorin-III and tetratricopeptide repeat (TPR) domains. Apolipophorin-III play vital roles in the transport
EVI5L
Vertebrate receptor protein and transcription factor
cytoplasmic protein that interacts with the Ah receptor, contains tetratricopeptide repeat motifs, and augments the transcriptional response to 2,3,7
Aryl_hydrocarbon_receptor
Protein-coding gene in the species Homo sapiens
well as to a site on hsp90 that is topologically adjacent to the tetratricopeptide repeat binding site". The Journal of Biological Chemistry. 273 (32): 20090–5
Heat shock protein 90kDa alpha (cytosolic), member A1
Heat_shock_protein_90kDa_alpha_(cytosolic),_member_A1
Topics referred to by the same term
machine translation user dictionaries. Ubiquitously transcribed tetratricopeptide repeat, X chromosome, a human gene. This disambiguation page lists articles
UTX
Protein
Box RNA helices, Box3, Y-linked (DBY), Ubiquitously Transcribed Tetratricopeptide Repeat Containing, Y-linked (UTY), and Thymosin Beta 4, Y-Linked (TB4Y)
Azoospermia_factor
Post-translational carbohydrate modification of proteins
Recognizes Protein Substrates Using an Asparagine Ladder in the Tetratricopeptide Repeat (TPR) Superhelix". Journal of the American Chemical Society. 140
O-GlcNAc
Enzyme
peptide-substrate-binding domain of collagen prolyl 4-hydroxylases is a tetratricopeptide repeat domain with functional aromatic residues". The Journal of Biological
Procollagen-proline dioxygenase
Procollagen-proline_dioxygenase
Reproductive gene and associated protein
chromosome 3 at position 26.31 (reverse strand) and is a member of the tetratricopeptide repeat-like superfamily, which facilitate interactions and assemblies
SPATA16
Medical condition
needed] The syndrome appears to be due to mutations in the gene tetratricopeptide repeat domain 37 (TTC37), which encodes the protein Thespin or the SKIV2L
Tricho-hepato-enteric syndrome
Tricho-hepato-enteric_syndrome
Cytoplasmic biomolecular condensates of proteins and RNA occurring in cells under stress
protein 6 TROVE2 RORNP TROVE Domain Family Member 2 TTC17 TTC17 Tetratricopeptide Repeat Domain 17 yes TUBA1C TUBA1C Tubulin alpha-1C chain TUBA3C TUBA3C
Stress_granule
Protein-coding gene in the species Homo sapiens
revealed that Naa15 is composed of 13 conserved helical bundle tetratricopeptide repeat (TPR) motifs and adopts a ring-like topology that wraps around
NAA15
Protein-coding gene in humans
protein and 3 other members of the APC complex contain the TPR (tetratricopeptide repeat), a protein domain important for protein-protein interaction. CDC23
CDC23
Protein-coding gene in the species Homo sapiens
LD, Jirtle RL, Isenberg JS, Klounig JE, Woychik RP (1997). "The tetratricopeptide repeat containing Tg737 gene is a liver neoplasia tumor suppressor gene"
IFT88
Protein-coding gene in the species Homo sapiens
recycling factor p110: mutational analysis reveals the function of the tetratricopeptide repeat domain in recycling". Molecular and Cellular Biology. 24 (17):
SART3
Protein-coding gene in the species Homo sapiens
Vermeulen W, Kamiuchi S, et al. (November 2000). "XAB2, a novel tetratricopeptide repeat protein involved in transcription-coupled DNA repair and transcription"
XPA
Protein-coding gene in the species Homo sapiens
interactions include BCL2L13 (BCL2-like 13), SGTA (Small glutamine-rich tetratricopeptide repeat-containing protein), and UBQLN1 (Ubiquilin-1). GRCm38: Ensembl
TMUB2
Protein found in humans
cytoplasmic protein that interacts with the Ah receptor, contains tetratricopeptide repeat motifs, and augments the transcriptional response to 2,3,7
AH receptor-interacting protein
AH_receptor-interacting_protein
Protein-coding gene in the species Homo sapiens
Interferon-induced protein with tetratricopeptide repeats 2 (commonly termed IFIT2) is a protein that in humans is directed to be produced by the IFIT2
IFIT2
Protein-coding gene in the species Homo sapiens
Bianchetta MJ, Lanken J, Cohen JB (March 2001). "Role of rapsyn tetratricopeptide repeat and coiled-coil domains in self-association and nicotinic acetylcholine
RAPSN
1186/s40364-022-00396-y. PMC 9281127. PMID 35831911. "SGTA small glutamine rich tetratricopeptide repeat co-chaperone alpha [Homo sapiens (human)]". - Gene - NCBI. U.S
ZG16
Protein-coding gene in the species Homo sapiens
ODAD4 Identifiers Aliases ODAD4, tetratricopeptide repeat domain 25, TTC25, outer dynein arm docking complex subunit 4 External IDs OMIM: 617095; MGI:
ODAD4
Genus of bacteria
synthesis enzyme MnmG, O-succinylbenzoate-CoA ligase, tetratricopeptide repeat protein, d-alanyl-d-alanine carboxypeptidase, ribonuclease Z, late
Caldibacillus
Protein-coding gene in the species Homo sapiens
truncated form of the G-protein regulator AGS3 in heart that lacks the tetratricopeptide repeat domains". J Biol Chem. 276 (20): 16601–10. doi:10.1074/jbc.M007573200
GPSM1
which are the SS/TM (signal sequence/transmembrane domain),TPR (tetratricopeptide repeat) domain and fic (filamentation induced by cAMP) domain. The secondary
FICD
Protein-coding gene in the species Homo sapiens
LY, Patterson C (June 1999). "Identification of CHIP, a novel tetratricopeptide repeat-containing protein that interacts with heat shock proteins and
HSPA1A
Protein complex involved in cilium biogenesis
of BBS1/BBS2/BBS7 with β-propeller domains, BBS4/BBS8 with TPR (tetratricopeptide repeat) regions, BBS3/Arl6, and BBS6/BBS10/BBS12 relations for chaperonin-like
BBSome
Family of heat shock proteins
and acts as a ubiquitin ligase for clients. CHIP, chromatin immunoprecipitation; Hsp70, heat shock protein 70 kDa; TPR, tetratricopeptide repeat domain
Hsp70
Class of enzymes
structure most of them fall into two groups: J-domain proteins and tetratricopeptide repeats (TPR). Co-chaperones assist heat shock proteins in the protein
Co-chaperone
Protein-coding gene in the species Homo sapiens
Yin LY, Patterson C (Jun 1999). "Identification of CHIP, a novel tetratricopeptide repeat-containing protein that interacts with heat shock proteins and
STUB1
Protein involved in the binding of the growth hormone
M, De Jong AP, Strous GJ (August 2003). "Small glutamine-rich tetratricopeptide repeat-containing protein (SGT) interacts with the ubiquitin-dependent
Growth_hormone_receptor
Protein-coding gene in the species Homo sapiens
paralogs to this gene: forkhead box protein (FOX), and SH3 domain and tetratricopeptide repeat-containing protein 2 (SH3TC2). C6orf118 and FOX in humans have
C6orf118
Post-translational modification
and long C-terminal portion that resides in ER and encompasses tetratricopeptide repeats (TPRs) followed by a catalytic Fic domain. The discovery of an
Adenylylation
Protein-coding gene in the species Homo sapiens
(Nov 1996). "Identification and characterization of two novel tetratricopeptide repeat-containing genes". DNA Cell Biol. 15 (9): 727–35. doi:10.1089/dna
DNAJC7
Signaling pathway
reversion to ethylene sensitivity 1 (RTE1), cytochrome b5 and tetratricopeptide repeat protein 1 (TRP1) also play important roles in ethylene signaling
Ethylene_signaling_pathway
Protein-coding gene in humans
S2CID 7955950. Marty C, Browning DD, Ye RD (Jun 2003). "Identification of tetratricopeptide repeat 1 as an adaptor protein that interacts with heterotrimeric G proteins
GPSM2
Protein-coding gene in humans
PMID 10906137. Marty C, Browning DD, Ye RD (Jun 2003). "Identification of tetratricopeptide repeat 1 as an adaptor protein that interacts with heterotrimeric G proteins
GNAI2
Protein-coding gene in the species Homo sapiens
PMC 139241. PMID 12477932. Iyer SP, Hart GW (2003). "Roles of the tetratricopeptide repeat domain in O-GlcNAc transferase targeting and protein substrate
TRAK1
Protein-coding gene in the species Homo sapiens
Yin LY, Patterson C (Jun 1999). "Identification of CHIP, a novel tetratricopeptide repeat-containing protein that interacts with heat shock proteins and
HSPA4
Protein-coding gene in humans
different isoforms have been found for this gene. This gene encodes a tetratricopeptide repeat containing component of the anaphase-promoting complex/cyclosome
ANAPC7
achieve polarized distribution of cortical factors. N-terminal tetratricopeptide repeats (TPRs) in Pins is the binding region for Mud, but is autoinhibited
Ultrasensitivity
Protein-coding gene in humans
well as to a site on hsp90 that is topologically adjacent to the tetratricopeptide repeat binding site". The Journal of Biological Chemistry. 273 (32): 20090–20095
CDC37
Predicted Partner Protein Score Associated Functions Tetratricopeptide Repeat Domain 29 (TTC29) 0.680 Shown to be significantly upregulated during wound
Glutamate-rich_protein_4
Protein found in humans
"p150TSP, a conserved nuclear phosphoprotein that contains multiple tetratricopeptide repeats and binds specifically to SH2 domains". J. Biol. Chem. 271 (12):
Tyrosine-protein_kinase_BLK
Gene of the kinesin light chain family
with kinesin heavy chain through an N-terminal domain, and six tetratricopeptide repeat (TPR) motifs are thought to be involved in binding of cargos such
KLC1
Enzyme
human protein serine/threonine phosphatase, which possesses four tetratricopeptide repeat motifs and localizes to the nucleus". The EMBO Journal. 13 (18):
PPP5C
Protein-coding gene in the species Homo sapiens
to the NTD and CTD. The latter Co-chaperones usually contain a tetratricopeptide repeat (TPR) domain which binds to a MEEVD motif at the C-terminus of
HSP90AB1
Protein-coding gene in the species Homo sapiens
1101/gr.6.9.791. PMID 8889548. Takaishi M, Huh N (October 1999). "A tetratricopeptide repeat-containing protein gene, tpis, whose expression is induced with
Sperm-associated_antigen_1
Protein-coding gene in humans
and two other APC complex proteins, CDC23 and CDC27, contain a tetratricopeptide repeat (TPR), a protein domain that may be involved in protein-protein
CDC16
Protein-coding gene in the species Homo sapiens
structure of human Bub1 revealed the presence of a N-terminal tetratricopeptide repeat (TPR) domain and a C-terminal kinase domain (residues 784–1085)
BUB1
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TETRATRICOPEPTIDE REPEAT
TETRATRICOPEPTIDE REPEAT
TETRATRICOPEPTIDE REPEAT
TETRATRICOPEPTIDE REPEAT
TETRATRICOPEPTIDE REPEAT
TETRATRICOPEPTIDE REPEAT
TETRATRICOPEPTIDE REPEAT
TETRATRICOPEPTIDE REPEAT
TETRATRICOPEPTIDE REPEAT
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