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Protein-coding gene in the species Homo sapiens
kinase BUB1 also known as BUB1 (budding uninhibited by benzimidazoles 1) is an enzyme that in humans is encoded by the BUB1 gene. Bub1 is a serine/threonine
BUB1
Medical condition
because of it, some cells are aneuploid (mosaic). It is caused by mutation BUB1, BUB1B, BUB3, CEP57 or TRIP13. Person with MVA can present with IUGR, microcephaly
Mosaic variegated aneuploidy syndrome
Mosaic_variegated_aneuploidy_syndrome
Protein-coding gene in the species Homo sapiens
Bub3 specifically binds Mad3 and Bub1, Rae1 has more promiscuous binding as it binds both the nuclear pore complex and Bub1. This indicates a similarity in
BUB3
Protein-coding gene in the species Homo sapiens
nucleosome, which is the important substrate of spindle checkpoint kinase BUB1. Centromeric cohesin and H2A-pT120 specify two distinct pools of Sgo1-PP2A
Shugoshin_1
Protein-coding gene in the species Homo sapiens
Mitotic checkpoint serine/threonine-protein kinase BUB1 beta is an enzyme that in humans is encoded by the BUB1B gene. Also known as BubR1, this protein
BUB1B
Cell cycle checkpoint
benzimidazole), and CDC20. Other proteins involved in the SAC include MAD1, BUB1, MPS1, and Aurora B. For higher eukaryotes, additional regulators of the
Spindle_checkpoint
Protein complex that allows microtubules to attach to chromosomes during cell division
lower the concentrations of these proteins. At metaphase, CENP-E, Bub3 and Bub1 levels diminish by a factor of about three to four as compared with free
Kinetochore
Family of transcription factors
Negative regulators: E2F7, RB1, TP107, TP21 Checkpoints: TP53, BRCA1,2, BUB1 Apoptosis: TP73, APAF1, CASP3,7,8, MAP3K5,14 Nucleotide synthesis: thymidine
E2F
Chemical compound
study the cell cycle in yeast; in fact, the name of the protein class "Bub" (Bub1, etc.) comes from their mutant in which budding was uninhibited by benomyl
Benomyl
Mammalian protein found in humans
derivatives of all three germ layers. POU5F1, TDGF1 (CRIPTO), SALL4, LECT1, and BUB1 are also related genes all responsible for self-renewal and pluripotent differentiation
Homeobox_protein_NANOG
Topics referred to by the same term
her unique appearance Bub, an alligator antagonist in Dog Man Human genes: BUB1, budding uninhibited by benzimidazoles 1 homolog (yeast) BUB1B, budding uninhibited
Bub
Protein family
and a highly conserved C-terminal region. Shugoshin is a crucial target of Bub1 kinase that plays a central role in the cohesion of chromosomes during cell
Shugoshin N terminal protein domain
Shugoshin_N_terminal_protein_domain
Protein-coding gene in the species Homo sapiens
Seeley TW, Wang L, Zhen JY (1999). "Phosphorylation of human MAD1 by the BUB1 kinase in vitro". Biochem. Biophys. Res. Commun. 257 (2): 589–595. doi:10
EIF4EBP1
Protein domain
BLK ; BMP2K ; BMPR1A ; BMPR1B ; BMPR2 ; BMX ; BRAF ; BRSK1 ; BRSK2 ; BTK ; BUB1 ; BUB1B ; CAMK1 ; CAMK1D ; CAMK1G ; CAMK2A ; CAMK2B ; CAMK2D ; CAMK2G ; CAMK4 ;
Protein_kinase_domain
Protein-coding gene in humans
org. Retrieved 2016-05-10. "BUB1 - Mitotic checkpoint serine/threonine-protein kinase BUB1 - Homo sapiens (Human) - BUB1 gene & protein". www.uniprot
CCDC180
Protein found in humans
schizophrenia. (29) APC (gene) has been shown to interact with: ARHGEF4, AXIN1, BUB1, CTNNB1, CSNK2B, CSNK2A1, Catenin (cadherin-associated protein), alpha 1
Adenomatous_polyposis_coli
Protein-coding gene in humans
inhibits APC/CCdc20 so that anaphase cannot begin prematurely. Moreover, Bub1 phosphorylates and thus inhibits CDC20 directly, while in yeast Mad2 and
CDC20
Protein
during fetal brain development. CASC5 has been shown to interact with MIS12, BUB1, BUBR1 and ZWINT-1. Homozygous polymorphisms in the CASC5 gene have been
KNL1
HGNC:26131; Q6UX41 1726 BTNL9 HGNC:24176; Q6UXG8 1727 BTRC HGNC:1144; Q9Y297 1728 BUB1 HGNC:1148; O43683 1729 BUB1B HGNC:1149; O60566 1730 BUB3 HGNC:1151; O43684
List of human protein-coding genes 1
List_of_human_protein-coding_genes_1
Essential spindle checkpoint protein
and the contribution of other spindle checkpoint assembly proteins such as Bub1, BubR1, and Bub3. BubR1 and Bub3 can also form complexes with Cdc20, but
Mad2
Protein-coding gene in the species Mus musculus
Mad1 and Mad2 localization to kinetochores and their interaction dynamics. BUB1 is the other kinase that recruits Mad1 to kinetochores and activates it if
Mad1
Protein-coding gene in the species Homo sapiens
HDAC1 has been shown to interact with: Androgen receptor, BCL6, BTG2, BUB1B, BUB1, BUB3, CBFA2T3, CDC20, CDH1, CHD3, CHD4, COUP-TFII, CTBP1, DDX17, DDX5, DNMT3A
HDAC1
Protein-coding gene in humans
Zambroni D, Indino E, Barbieri O, Citti L, et al. (June 2003). "Inhibition of BUB1 results in genomic instability and anchorage-independent growth of normal
SMC1A
Protein-coding gene in the species Homo sapiens
PR, Lacroix FB, Wilson L, Margolis RL (April 2001). "Mammalian mad2 and bub1/bubR1 recognize distinct spindle-attachment and kinetochore-tension checkpoints"
MAD2L1
BUB1
BUB1
BUB1
BUB1
Boy/Male
American, British, Danish, English, Finnish, French, German, Greek, Hindu, Indian, Italian, Jamaican, Latin, Polish, Swedish
Revered; Exalted; Worthy of Respect; Great; Magnificent; Great or Venerable; Majestic
Boy/Male
Tamil
Pleasing
Boy/Male
Indian, Sanskrit
Coil of Rope; Ring
Boy/Male
Tamil
Name of a sage
Surname or Lastname
English
English : nickname from Middle English stif ‘rigid’, ‘inflexible’, hence a nickname for someone who had difficulty in bending. The term was also used in a transferred sense of character (generally in the approving sense ‘resolute’, ‘steadfast’) from the 12th century, and this use may lie behind many examples of the surname.
Male
Greek
(ΑτÏεÏÏ‚) Greek name ATREUS means fearless." In mythology, this is the name of a king of Mycenae, the father of Agamemnon.
Girl/Female
Indian
Summit of a mountain
Female
English
Anglicized form of Welsh Gwyneth, GYNETH means "luck, happiness." In Arthurian legend, this is the name of the daughter of King Arthur, in Sir Walter Scott's The Bridal of Triermain.Â
Girl/Female
Indian
Love
Surname or Lastname
English (chiefly Midlands)
English (chiefly Midlands) : variant spelling of Heard.
BUB1
BUB1
BUB1
BUB1
BUB1