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Biological gene-regulation phenomenon
RNA activation (RNAa) is a small RNA-guided and Argonaute (Ago)-dependent gene regulation phenomenon in which promoter-targeted short double-stranded RNAs
RNA_activation
Biomolecule
phenomenon termed "RNA activation" or RNAa. This was first observed when synthetic siRNAs, termed "small activating RNA" (saRNA), targeting gene promoters
Small_interfering_RNA
Type of RNA that activates transcription of specific genes
Small activating RNAs (saRNAs) are small double-stranded RNAs (dsRNAs) that target gene promoters to induce transcriptional gene activation in a process
Small_activating_RNA
Indian-American academic scientist
classical RNA interference (RNAi) mechanism of gene silencing. They coined the terms “RNA activation (RNAa)” and “small activating RNA (saRNA)”, establishing
Rajvir_Dahiya
Process of copying a segment of DNA into RNA
RNA for the purpose of gene expression. Some segments of DNA are transcribed into RNA molecules that can encode proteins, called messenger RNA (mRNA)
Transcription_(biology)
Family of large biological molecules
transfer RNA (tRNA), microRNA (miRNA), small interfering RNA (siRNA), small nucleolar RNA (snoRNAs), Piwi-interacting RNA (piRNA), tRNA-derived small RNA (tsRNA)
RNA
Medications based on ribonucleic acids
on messenger RNA (mRNA), antisense RNA (asRNA), RNA interference (RNAi), RNA activation (RNAa) and RNA aptamers. Of the four types, mRNA-based therapy
RNA_therapeutics
Type of CRISPR tool
for activation of transcription. The activation domain can recruit general transcription factors or RNA polymerase to the gene sequence. Activation domains
CRISPR_activation
Type of virus according to Baltimore classification
template by the viral RNA dependent RNA polymerase (RdRp) to transcribe a positive-strand RNA functioning as messenger RNA (mRNA) for the host cell's ribosomes
Double-stranded_RNA_viruses
Human protein and coding gene
to PKR molecules. However, excess dsRNA can diminish activation of PKR. Binding to dsRNA is believed to activate PKR by inducing dimerization of the kinase
Protein_kinase_R
Process of attaching Amino acids to their tRNA
acid activation (also known as aminoacylation or tRNA charging) refers to the attachment of an amino acid to its respective transfer RNA (tRNA). The
Amino_acid_activation
Protein that increases transcription of a gene or set of genes
Other activators help promote gene transcription by triggering RNA polymerase to release from the promoter and proceed along the DNA. At times, RNA polymerase
Activator_(genetics)
Group of antiviral drugs
DRACO (double-stranded RNA activated caspase oligomerizer) is a group of experimental antiviral drugs formerly under development at the Massachusetts
Double-stranded RNA activated caspase oligomerizer
Double-stranded_RNA_activated_caspase_oligomerizer
Type of RNA
well as interferon response in vertebrates. In eukaryotes, dsRNA plays a role in the activation of the innate immune system against viral infections. Watson
Double-stranded_RNA
RNA produced by transcription
ribonucleic acid (RNA) product synthesized by transcription of DNA, and processed to yield various mature RNA products such as mRNAs, tRNAs, and rRNAs. The primary
Primary_transcript
Protein-coding gene in the species Homo sapiens
receptor RNA activator 1 also known as steroid receptor RNA activator protein (SRAP) is a protein that in humans is encoded by the SRA1 gene. The mRNA transcribed
SRA1
Type of non-coding RNA molecule
many IEGs, eRNA induction precedes mRNA induction in response to neuronal activation. While some enhancers can activate their target promoters at their target
Enhancer_RNA
Biological molecule
In molecular biology, trans-activating CRISPR RNA (tracrRNA) is a small trans-encoded RNA. It was first discovered by Emmanuelle Charpentier in her study
Trans-activating_crRNA
Mammalian protein found in humans
double-stranded RNA-specific adenosine deaminase enzyme family are encoded by the ADAR family genes. ADAR stands for adenosine deaminase acting on RNA. This article
ADAR
Type of long noncoding RNA
Noncoding RNA Activated by DNA Damage (NORAD) is a long non-coding RNA (lncRNA) that responds to DNA damage and plays a significant role in preserving
Noncoding RNA Activated by DNA Damage
Noncoding_RNA_Activated_by_DNA_Damage
RNA that is read by the ribosome to produce a protein
Messenger ribonucleic acid (mRNA) is a single-stranded molecule of RNA that corresponds to the genetic sequence of a gene, and is read by a ribosome in
Messenger_RNA
Non-protein coding transcripts longer than 200 nucleotides
ncRNAs from small non-coding RNAs, such as microRNAs (miRNAs), small interfering RNAs (siRNAs), Piwi-interacting RNAs (piRNAs), small nucleolar RNAs (snoRNAs)
Long_non-coding_RNA
Modification of the CRISPR/Cas9 system for genome editing
gene activation through direct activation imply the sgRNA variant binds and targets dCas9 efficiently. All the five topologies showed direct activation except
CRISPR-Display
Class of ribonucleic acid that is not translated into proteins
RNAs (rRNAs), as well as small RNAs such as microRNAs, siRNAs, piRNAs, snoRNAs, snRNAs, exRNAs, scaRNAs and the long ncRNAs such as Xist, HOTAIR, and MALAT1
Non-coding_RNA
Type of vaccine
An mRNA vaccine is a type of vaccine that uses a copy of a molecule called messenger RNA (mRNA) to produce an immune response. The vaccine delivers molecules
MRNA_vaccine
NamiRNAs are a type of miRNAs present in the nucleus, which can activate gene expression by binding to the enhancer, and therefore were named nuclear activating
NamiRNAs
Hypothetical stage in the early evolutionary history of life on Earth
The RNA world is a hypothetical stage in the evolutionary history of life on Earth in which self-replicating RNA molecules proliferated before the evolution
RNA_world
Stage in embryonic development
"Setting the stage for development: mRNA translation and stability during ooccyte maturation and egg activation in Drosophila". Dev Dyn. 232 (3): 593–608
Maternal to zygotic transition
Maternal_to_zygotic_transition
Biological process of gene regulation
ribonucleic acid (RNA) molecules, microRNA (miRNA) and small interfering RNA (siRNA), are central to components to the RNAi pathway. Once mRNA is degraded,
RNA_interference
Biological cell regulation mechanisms
needed] RNA can be an important regulator of gene activity, e.g. by microRNA (miRNA), antisense-RNA, or long non-coding RNA (lncRNA). LncRNAs differ from
Regulation_of_gene_expression
RNA family
The trans-activation response (TAR) element is an RNA element which is known to be required for the trans-activation of the HIV promoter and for HIV replication
Trans-activation response element
Trans-activation_response_element
Multiprotein complex
levels. Using single-stranded RNA (ssRNA) fragments, such as microRNA (miRNA), or double-stranded small interfering RNA (siRNA), the complex functions as
RNA-induced_silencing_complex
Microbial protein found in Streptococcus pyogenes M1 GAS
endonuclease that requires a guide RNA composed of two distinct RNA molecules: CRISPR RNA (crRNA) and trans-activating crRNA (tracrRNA). In 2013, Mali, et al. and
Cas9
Small non-coding ribonucleic acid molecule
and mir-19. dsRNA can also activate gene expression, a mechanism that has been termed "small RNA-induced gene activation" or RNAa. dsRNAs targeting gene
MicroRNA
Process of introducing nucleic acids into eukaryotic cells
with RNA messages". San Francisco Chronicle. Alexopoulou L, Holt AC, Medzhitov R, Flavell RA (2001). "Recognition of double-stranded RNA and activation of
Transfection
function of an upstream activation sequence, it is beneficial to see its role in the cascade of events that lead to transcription activation. The pathway begins
Upstream_activating_sequence
Conversion of a gene's sequence into a mature gene product or products
also some non-coding RNAs (e.g., snRNAs, snoRNAs or long non-coding RNAs). RNA polymerase III transcribes 5S rRNA, transfer RNA (tRNA) genes, and some small
Gene_expression
Concept in chemistry and biology
chemistry and biology, activation is the process whereby something is prepared or excited for a subsequent reaction. In chemistry, "activation" refers to the
Activation
competing endogenous RNAs (abbreviated ceRNAs) regulate other RNA transcripts by competing for shared microRNAs (miRNAs). Models for ceRNA regulation describe
Competing_endogenous_RNA
Inactivation of copies of X chromosome
zygotic genome activation, leading to: XaP XaM → undergoing imprinted (paternal) X-inactivation, leading to: XiP XaM → undergoing X-activation in the early
X-inactivation
Region of DNA encouraging transcription
for RNA polymerase and for proteins called transcription factors that recruit RNA polymerase. These transcription factors have specific activator or repressor
Promoter_(genetics)
Protein family
protein. As a consequence of its binding to dsRNA, the NS1 protein blocks the activation of the dsRNA-activated protein kinase (PKR) in vitro. This kinase
NS1_influenza_protein
Genetics sequence
RNA guides, to recognize and target RNA molecules. These systems primarily utilize Cas12a and variants such as Cas12i1 to separate protein activation
DNA-guided_CRISPR
Process in molecular biology
RNA splicing is a process in molecular biology where a newly-made precursor messenger RNA (pre-mRNA) transcript is transformed into a mature messenger
RNA_splicing
Family of DNA sequences found in prokaryotic organisms
requires only a CRISPR RNA (crRNA) for effective targeting, whereas Cas9 necessitates both a crRNA and a trans-activating crRNA (tracrRNA). Originally introduced
CRISPR
Non-coding RNA found in adenovirus
long RNAs that can act as siRNA or miRNA. VAI RNA functions as a decoy RNA for the double stranded RNA activated protein kinase R which would otherwise
VA_RNA
Enzyme that synthesizes RNA from an RNA template
RNA-dependent RNA polymerase (RdRp) or RNA replicase is an enzyme that catalyzes the replication of RNA from an RNA template. Specifically, it catalyzes
RNA-dependent_RNA_polymerase
simple identification of dsRNA structure and likely relies on other epigenetic markers. dsRNA has been implicated in the activation of the interferon system
Viral strategies for immune response evasion
Viral_strategies_for_immune_response_evasion
virulence. Two ToxT activated RNAs have been described: TarA (ToxT activated RNA A) and TarB (ToxT activated RNA B). The TarA small RNA regulates PtsG, a
Vibrio cholerae ToxT activated RNAs
Vibrio_cholerae_ToxT_activated_RNAs
Protein found in humans
receptor activation, triggering a calcium influx. Through a protein signaling cascade requiring Erk, CaM KII/IV, PI3K, and PLC, NMDA receptor activation is
Brain-derived neurotrophic factor
Brain-derived_neurotrophic_factor
Addition of adenylic acids to 3' end of mature mRNA
Polyadenylation is the addition of a poly(A) tail to an RNA transcript, typically a messenger RNA (mRNA). The poly(A) tail consists of multiple adenosine monophosphates;
Polyadenylation
Enzyme that cleaves double-stranded RNA (dsRNA) into short dsRNA fragments
the 3′-end. Dicer facilitates the activation of the RNA-induced silencing complex (RISC), which is essential for RNA interference. RISC has a catalytic
Dicer
Protein-coding gene in the species Homo sapiens
snRNA-activating protein complex subunit 1 is a protein that in humans is encoded by the SNAPC1 gene. SNAPC1 has been shown to interact with SNAPC4, SNAPC3
SNAPC1
RNA component of the ribosome, essential for protein synthesis in all living organisms
transfer RNA (tRNA) and messenger RNA (mRNA) to process and translate the latter into proteins. Ribosomal RNA is the predominant form of RNA found in
Ribosomal_RNA
Protein-coding gene in the species Homo sapiens
associated with the activation of selective autophagy. Mycobacterium tuberculosis has been shown to produce cytosolic DNA ligands which activate STING, resulting
Stimulator of interferon genes
Stimulator_of_interferon_genes
Cellular process of protein synthesis
produced using RNA molecules as templates. The generated protein is a sequence of amino acids determined by the sequence of nucleotides in the RNA. The nucleotides
Translation_(biology)
Mechanism triggered in mammalian cells by amino acid starvation
concentration of amino acid, GCN2 is activated due to the increase level of uncharged tRNA molecules. Uncharged tRNA activates GCN2 due to the displacement of
Amino_acid_response
Protein-coding gene in the species Homo sapiens
viral RNA that they recognize, but they share many structural features, including the N-terminal CARD that allows them to bind to MAVS. MAVS activation leads
Mitochondrial antiviral-signaling protein
Mitochondrial_antiviral-signaling_protein
Protein found in humans
family and detects single stranded RNA. The TLR family plays an important role in pathogen recognition and activation of innate immunity. TLRs are highly
Toll-like_receptor_7
Process by which a gene can code for multiple proteins
Alternative splicing, alternative RNA splicing, or differential splicing is an alternative splicing process during gene expression that allows a single
Alternative_splicing
RNA family
novel ncRNAs in E. coli. The GlmY sRNA has been shown to activate the synthesis of GlmS. It achieves this by influencing the action of another sRNA called
GlmY_RNA
Class of enzymes that unpack genetic material
achieved through the lowering of the activation barrier ( B {\displaystyle B} ) of each specific action. The activation barrier is a result of various factors
Helicase
RNA molecule that specifies a target sequence
Guide RNA (gRNA) or single guide RNA (sgRNA) is a short sequence of RNA that guides a CRISPR-associated protein to its nucleic acid sequence target by
Guide_RNA
Chemical compound
Ramanarayanan; Mutschler, Hannes (2020). "Prebiotically Plausible RNA Activation Compatible with Ribozyme-Catalyzed Ligation". Angewandte Chemie International
Diamidophosphate
Chemical compound
as well as allosterically activating enzymes such as myophosphorylase-b. AMP is also a component in the synthesis of RNA. AMP is present in all known
Adenosine_monophosphate
Protein-coding gene in the species Homo sapiens
inflammasome activation and inflammatory cell death, PANoptosis, during influenza A virus infection. ZBP1-deficient mice showed impaired activation of inflammasome
ZBP1
Protein-coding gene in the species Homo sapiens
and specifies IRF3 phosphorylation and activation by the Serine/threonine-protein kinase TBK1, thereby activating the production of type-I interferons.
IRF3
Topics referred to by the same term
RNAA may mean: RNA activation, a small RNA-guided gene regulation phenomenon Radiochemical Neutron Activation Analysis, a nuclear process used for determining
RNAa
Type of RNA found in cells
acid (or circRNA) is a type of single-stranded RNA which, unlike linear RNA, forms a covalently closed continuous loop. In circular RNA, the 3' and 5'
Circular_RNA
Protein-coding gene in humans
snRNA-activating protein complex subunit 4 is a protein that in humans is encoded by the SNAPC4 gene. SNAPC4 has been shown to interact with SNAPC1, POU2F1
SNAPC4
Enzyme found in humans
ribonuclease which, upon activation, destroys all RNA within the cell (both cellular and viral) as well as inhibiting mRNA export. RNase L is an enzyme
Ribonuclease_L
Trans-acting transcriptional activator
upstream from the site at which RNA polymerase binds and activates transcription through protein-protein interactions with RNA polymerase's α-subunit. This
Catabolite_activator_protein
(tRNA), ribosomal RNA (rRNA), microRNA (miRNA), and small interfering RNA (siRNA); other non-coding RNAs (sometimes described as "junk RNA") have no known
Glossary of cellular and molecular biology (M–Z)
Glossary_of_cellular_and_molecular_biology_(M–Z)
Type of RNA molecules
(ribonucleic acid enzymes) are RNA molecules that have the ability to catalyze specific biochemical reactions, including RNA splicing in gene expression
Ribozyme
Specific genus of RNA viruses
of the virus particle and is an RNA-dependent RNA polymerase enzyme. In an infected cell, this enzyme produces mRNA transcripts for the synthesis of
Rotavirus
Protein that regulates the rate of DNA transcription
proteins in a complex, by promoting (as an activator), or blocking (as a repressor) the recruitment of RNA polymerase (the enzyme that performs the transcription
Transcription_factor
Protein-coding gene in the species Homo sapiens
snRNA-activating protein complex subunit 3 is a protein that in humans is encoded by the SNAPC3 gene. SNAPC3 has been shown to interact with SNAPC1 and
SNAPC3
Small non-coding RNA (ncRNA)
Kalamorz F, Hajnsdorf E, Görke B (2008). "The small RNA GlmY acts upstream of the sRNA GlmZ in the activation of glmS expression and is subject to regulation
GlmZ_RNA
Protein found in humans
synthesis. TLR8 recognizes single-stranded RNA of viruses such as HIV and HCV. TLR8 is also involved in the activation of dendritic cells to produce inflammatory
Toll-like_receptor_8
Structure in lactic-acid bacterium RNA
RNA motif is a conserved RNA structure found in certain lactic acid bacteria. The asd motif was detected by bioinformatics and an individual asd RNA in
Asd_RNA_motif
Regulatory protein in bacteria
and RNA polymerase assist binding of RNA polymerase to the promoter. Busby S., Ebright RH. (1999). "Transcription activation by catabolite activator protein
CAMP_receptor_protein
patients, signs of UPRmt -activation have been demonstrated. In particular, mitochondrial dysfunction and UPRmt -activation have been linked to intestinal
Mitochondrial unfolded protein response
Mitochondrial_unfolded_protein_response
Protein-coding gene in the species Homo sapiens
snRNA-activating protein complex subunit 2 is a protein that in humans is encoded by the SNAPC2 gene. SNAPC2 has been shown to interact with SNAPC4. GRCm38:
SNAPC2
Gene editing method
et al. (October 2013). "Multiplexed activation of endogenous genes by CRISPR-on, an RNA-guided transcriptional activator system". Cell Research. 23 (10):
CRISPR_gene_editing
Hungarian-American biochemist (born 1955)
reinstate her. Karikó's work includes scientific research on RNA-mediated immune activation, resulting in the co-discovery with Drew Weissman of the nucleoside
Katalin_Karikó
Protein complex for mRNA transcription
RNA polymerase II (RNAP II and Pol II) is a multiprotein complex that transcribes DNA into precursors of messenger RNA (mRNA) and most small nuclear RNA
RNA_polymerase_II
Multiprotein complex involved in transcription in eukaryotes
dissociating the kinase module and associating with RNA polymerase II for transcriptional activation. Mediator is located within the cell nucleus. It is
Mediator_(coactivator)
Form of eukaryotic RNA polymerase II
RNA polymerase II holoenzyme is a form of eukaryotic RNA polymerase II that is recruited to the promoters of protein-coding genes in living cells. It consists
RNA_polymerase_II_holoenzyme
Chemical compound
analog of double-stranded RNA and is a common tool for scientific research on the immune system. Poly I:C has been shown to activate schizophrenia-like behavior
Polyinosinic:polycytidylic acid
Polyinosinic:polycytidylic_acid
Study of DNA modifications that do not change its sequence
activation of transcription of immediate early genes (IEGs) that are important in memory formation, allowing their expression in mRNA, with peak mRNA
Epigenetics
Physiological response to sudden exposure to cold
Decreased ribosome function The bacteria uses the cytoplasmic membrane, RNA/DNA, and ribosomes as cold sensors in the cell, placing them in charge of
Cold_shock_response
Transcription is heterocatalytic function of DNA
transcribes small non-coding RNAs, including tRNAs, 5S rRNA, U6 snRNA, SRP RNA, and other stable short RNAs such as ribonuclease P RNA. RNA Polymerases I, II, and
Eukaryotic_transcription
Mammalian protein found in Homo sapiens
Rehwinkel J, Kato H, Takeuchi O, et al. (October 2009). "Activation of MDA5 requires higher-order RNA structures generated during virus infection". Journal
MDA5
Medication used to treat a viral infection
fewer than 24 base pairs during transcription. DRACO (double-stranded RNA activated caspase oligomerizer) is a group of experimental antiviral drugs initially
Antiviral_drug
Protein
syndrome (AIDS), contains an RNA genome that produces a chromosomally integrated DNA during the replicative cycle. Activation of HIV-1 gene expression by
TARBP2
Class of RNA-binding proteins found in viruses
nucleoproteins (NPs) are essential RNA-binding proteins encoded by many viruses, especially negative-sense single-stranded RNA (–ssRNA) viruses. They play crucial
Viral_nucleoprotein
Protein found in humans
subpopulation of the leukocytes. It recognizes dsRNA associated with viral infection, and induces the activation of IRF3 and NF-κB. Unlike other TLRs, TLR3
Toll-like_receptor_3
Telomere-restoring protein active in the most rapidly dividing cells
alterations are required in all cases: TERT activation, loss of p53 pathway function, loss of pRb pathway function, activation of the Ras or myc proto-oncogenes
Telomerase
NcRNA found in eukaryotes
Telomerase RNA component (TERC), also abbreviated TER or TR, is a non-coding RNA found in eukaryotes that is a component of the telomerase enzyme, which
Telomerase_RNA_component
Control of DNA to RNA conversion in cells
2003). "MAP kinase phosphorylation-dependent activation of Elk-1 leads to activation of the co-activator p300". The EMBO Journal. 22 (2): 281–91. doi:10
Transcriptional_regulation
RNA ACTIVATION
RNA ACTIVATION
Female
Scottish
 Variant spelling of English/Scottish Rhona, RONA means "wise ruler."
Male
Swedish
Pet form of Swedish Björn, BJÖRNE means "bear."
Female
Irish
Irish Gaelic name FÃONA means "vine."
Female
English
 Variant spelling of English Ornat, ORNA means "little sallow one." Compare with another form of Orna.
Female
English
 Variant spelling of English Oona, possibly ONA means "famine, hunger." Compare with another form of Ona.
Female
Hebrew
(×Ö¸×¨Ö°× Ö¸×”) Hebrew name ORNA means "let there be light" or "pine tree." Compare with another form of Orna.
Female
English
Anglicized form of Irish Gaelic Úna, probably UNA means "famine, hunger." Compare with another form of Una.
Female
English
Anglicized form of Irish Gaelic Eithne, ENA means "kernel."
Female
English
 Variant spelling of English/Scottish Rhona, RONA means "wise ruler." Compare with another form of Rona.
Female
German
 Feminine form of German Ernust, ERNA means "battle (to the death), serious business." Compare with another form of Erna.
Female
Hebrew
(×¨×„× Ö¸Ö¼×”) Hebrew name RONA means "joy." Compare with another form of Rona.
Male
Hebrew
Variant spelling of Hebrew unisex Rinnah, RINA means "shouting for joy."Â Compare with strictly feminine forms of Rina.
Girl/Female
English American
A names ending in 'ina' or 'ena' (ie. Christina) used as a nickname. Famous bearer: In 1906...
Female
Japanese
(è˜) Japanese name RAN means "lily" or "orchid."
Female
Native American
Native American Hopi name UNA means "remember." Compare with another form of Una.
Female
Spanish
 Spanish name RIA means "small river." Compare with another form of Ria.
Male
Swedish
Variant spelling of Swedish Göran, JÖRAN means "earth-worker, farmer."
Female
Spanish
Portuguese and Spanish form of Latin Anna, ANA means "favor; grace."Â Compare with another form of Ana.
Female
Hebrew
 Variant spelling of Hebrew unisex Rinnah, RINA means "shouting for joy." Compare with other forms of Rina.
Female
Scandinavian
Feminine form of Scandinavian Rune, RUNA means "secret lore."
RNA ACTIVATION
RNA ACTIVATION
Surname or Lastname
English (Kent)
English (Kent) : possibly a habitational name for someone from Denge or Dungeness in Kent.Perhaps also an altered spelling of French Danger.
Boy/Male
Native American
Brave.
Boy/Male
Indian, Tamil
Poetic Epithet of the Pandya Kings; Pron; Vazhudhi
Female
Egyptian
, a daughter of Rameses II.
Boy/Male
Indian, Punjabi, Sikh
Skylight
Boy/Male
Arabic, Muslim
Giver of Good Tidings
Surname or Lastname
English (Devon)
English (Devon) : habitational name from Tapeley in Devon, which Ekwall derives from Old English tæppa ‘peg’ + lēah ‘wood’, ‘clearing’, i.e. ‘wood where pegs are obtained’.
Boy/Male
British, English
From the Meadow with Shrubs
Boy/Male
Welsh
Rough; blessed.
Girl/Female
Latin
Defender of man.
RNA ACTIVATION
RNA ACTIVATION
RNA ACTIVATION
RNA ACTIVATION
RNA ACTIVATION
pl.
of Sacrarium
n.
Open robbery.
imp.
of Run
a. & adv.
No, not. See No.
adv.
Of each; an equal quantity; as, wine and honey, ana (or, contracted, aa), / ij., that is, of wine and honey, each, two ounces.
n.
Alt. of Arnee
n.
Formerly, a servant who ran in front of his master's carriage; a runner.
n.
Yarns coiled on a spun-yarn winch.
n.
A genus of anurous batrachians, including the common frogs.
adv.
By; beyond; as, he ran past.
a.
To be played on the stage a number of successive days or nights; as, the piece ran for six months.
n.
A disease; black jaundice. See Mel/na.
v. i.
To be charged with, or to contain much of, while flowing; as, the rivers ran blood.
n.
A roe; a deer.