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Pharmaceutical drug
Posaconazole, sold under the brand name Noxafil among others, is a triazole antifungal medication. It was approved for medical use in the European Union
Posaconazole
Ability of a solid material to exist in more than one form or crystal structure
I of posaconazole. The discovery of polymorphs of posaconazole increased rapidly and resulted in much research in crystallography of posaconazole. A methanol
Crystal_polymorphism
Medical condition
may require surgery. Systemic medications used include Itraconazole, posaconazole and amphotericin B. With treatment, most people will recover, but an
Sporotrichosis
Fungal infection of the lungs
infection-control. Antifungal prophylaxis can be given to high-risk patients. Posaconazole is often given as prophylaxis in severely immunocompromised patients
Aspergillosis
Fungal infection
next 14 days. It may need to be continued for longer. Isavuconazole and Posaconazole are alternatives. Surgery can be very drastic, and, in some cases of
Mucormycosis
American multinational pharmaceutical company
revenues) is an antibiotic used to treat urinary tract infections. Noxafil (posaconazole) ($0.2 billion in 2024 revenues) is a triazole antifungal. Winrevair
Merck_&_Co.
lonidamine melaminylthioarsenate melarsoprol nifurtimox pentamidine posaconazole puromycin quinapyramine salicylhydroxamic acid suramin tetraphenylporphine
Trypanocidal_agent
Class of heterocyclic compounds
were developed. Second-generation triazoles, including voriconazole, posaconazole and ravuconazole, are more potent and more active against resistant pathogens
Azole
meningoencephalitis (PAM) flagellation test Miltefosine, fluconazole, amphotericin B, posaconazole, voriconazole, targeted temperature management No JC virus Progressive
List_of_infectious_diseases
Medical condition
cases, but should not be used routinely due to its serious side effects. Posaconazole is effective in severe and refractory esophageal candidiasis. Mimidis
Esophageal_candidiasis
Chemical compound
anastrozole, fadrozole, bicalutamide, dexmedetomidine, ravuconazole, and posaconazole, have been proposed as potential adjuvant therapies in ER-positive breast
27-Hydroxycholesterol
Human and animal fungal infection
itraconazole may be given for up to year when the grains are black. Posaconazole is another option. Voriconazole can be used for infections caused by
Eumycetoma
Pharmaceutical fungicide or fungistatic used to treat and prevent mycosis
Cyproconazole Efinaconazole Epoxiconazole Fluconazole Isavuconazole Itraconazole Posaconazole Propiconazole Ravuconazole Terconazole Voriconazole Abafungin Allylamines
Antifungal
Rare and usually fatal brain infection by a protist
of swimming pools Treatment Miltefosine, fluconazole, amphotericin B, posaconazole, voriconazole, targeted temperature management Prognosis 98.5% fatality
Primary amoebic meningoencephalitis
Primary_amoebic_meningoencephalitis
Fluoroquinolone antibiotic
Naftopidil Naluzotan Nefazodone Niaprazine Oxypertine Pardoprunox pCPP pFPP Posaconazole S-14,506 S-14,671 S-15,535 SB-258,585 SB-271,046 SB-357,134 SB-399,885
Ciprofloxacin
Species of fungus
meningitis, combination therapy of amphotericin B and posaconazole led to clinical improvement. Posaconazole has been approved by the European Commission as
Coccidioides_immitis
Fungal infection
that involve a person's bones and joints. The antifungal medications posaconazole and voriconazole have also been used to treat coccidioidomycosis. Because
Coccidioidomycosis
Chemical compound
isavuconazole, itraconazole, voriconazole, pramiconazole, ravuconazole, and posaconazole. Triazole plant-protection fungicides include epoxiconazole, triadimenol [de]
Triazole
Species of fungus
auris isolates are resistant to voriconazole, while other triazoles (posaconazole, itraconazole, and isavuconazole) display better activity. Of isolates
Candida_auris
Drug for angina pectoris sold under many brand names
Naftopidil Naluzotan Nefazodone Niaprazine Oxypertine Pardoprunox pCPP pFPP Posaconazole S-14,506 S-14,671 S-15,535 SB-258,585 SB-271,046 SB-357,134 SB-399,885
Trimetazidine
Drug for erectile dysfunction and hypertension
Naftopidil Naluzotan Nefazodone Niaprazine Oxypertine Pardoprunox pCPP pFPP Posaconazole S-14,506 S-14,671 S-15,535 SB-258,585 SB-271,046 SB-357,134 SB-399,885
Sildenafil
Chemical compound
Messer SA, Hollis RJ, Jones RN (April 2002). "Antifungal activities of posaconazole, ravuconazole, and voriconazole compared to those of itraconazole and
Ravuconazole
Medication used to treat fungal infections
spectrum of activity than fluconazole (but not as broad as voriconazole or posaconazole). In particular, it is active against Aspergillus, which fluconazole
Itraconazole
Species of fungus
steroids, chemotherapy, and dialysis. Treatment includes amphotericin B, posaconazole, itraconazole, and fluconazole. The majority of the cases of infection
Rhizopus_oryzae
Fungal infection of the lungs
to 12 weeks treatment is sufficient. Alternatives to itraconazole are posaconazole, voriconazole, and fluconazole. Individuals taking itraconazole are monitored
Histoplasmosis
Medication used to treat insomnia
indinavir, itraconazole, ketoconazole, lopinavir, nefazodone, nelfinavir, posaconazole, ritonavir, saquinavir, telaprevir, and telithromycin (concomitant use
Daridorexant
Species of fungus
(1 April 2011). "In Vitro Susceptibility of Madurella mycetomatis to Posaconazole and Terbinafine". Antimicrobial Agents and Chemotherapy. 55 (4): 1771–3
Madurella_mycetomatis
Pharmaceutical company
(tibolone) Marvelon/Desogen Nasonex and Asmanex (Mometasone furoate) Noxafil (posaconazole) NuvaRing Puregon/Follistim Quazepam (Doral) Remeron/Remeron SolTab (mirtazapine)
Schering-Plough
Enzyme that metabolizes substances by oxidation
chloramphenicol (antibiotic) some azole antifungals: ketoconazole, itraconazole, posaconazole, voriconazole; cobicistat, green tea extract, grape seed extract, dillapiole
CYP3A4
Lipid-lowering medication
who are also taking the antifungal drugs fluconazole, itraconazole, or posaconazole; the antibiotics erythromycin, clarithromycin, or telithromycin; HIV
Simvastatin
Serotonergic drug
Naftopidil Naluzotan Nefazodone Niaprazine Oxypertine Pardoprunox pCPP pFPP Posaconazole S-14,506 S-14,671 S-15,535 SB-258,585 SB-271,046 SB-357,134 SB-399,885
Meta-Chlorophenylpiperazine
Use of existing drugs for new therapeutic purposes
leprosy and multiple myeloma. Clinical trials have been performed on posaconazole and ravuconazole for Chagas disease. Other antifungal agents clotrimazole
Drug_repositioning
Antidepressant medication
Naftopidil Naluzotan Nefazodone Niaprazine Oxypertine Pardoprunox pCPP pFPP Posaconazole S-14,506 S-14,671 S-15,535 SB-258,585 SB-271,046 SB-357,134 SB-399,885
Vilazodone
Species of fungus
antifungal drugs such as amphotericin B, itraconazole, voriconazole, posaconazole, and caspofungin; however, some antifungal resistance has been shown
Aspergillus_flavus
Antiretroviral medication
antifungal drugs like voriconazole, itraconazole, ketoconazole, and posaconazole. As a result of lowered levels, antifungal drugs may not be effective
Efavirenz
Chemical compound
Naftopidil Naluzotan Nefazodone Niaprazine Oxypertine Pardoprunox pCPP pFPP Posaconazole S-14,506 S-14,671 S-15,535 SB-258,585 SB-271,046 SB-357,134 SB-399,885
CGS-12066
Medical condition
antifungal drugs voriconazole, terbinafine, another antifungal azole posaconazole, and heat therapy. Antibiotics may be used to treat bacterial superinfections
Chromoblastomycosis
Fungal infection
voriconazole are first- and second-line antifungal agents respectively. Posaconazole or isavuconazole can be used as third-line agent for people with chronic
Chronic pulmonary aspergillosis
Chronic_pulmonary_aspergillosis
spectrum of activity than fluconazole (but not as broad as voriconazole or posaconazole). In particular, it is active against Aspergillus, which fluconazole
Fungistatics
Chemical compound
Naftopidil Naluzotan Nefazodone Niaprazine Oxypertine Pardoprunox pCPP pFPP Posaconazole S-14,506 S-14,671 S-15,535 SB-258,585 SB-271,046 SB-357,134 SB-399,885
Piperazine
picoxystrobin [Wikidata] piperalin [Wikidata] polycarbamate polyoxins polyoxorim posaconazole potassium azide potassium polysulfide [Wikidata] potassium thiocyanate
List_of_fungicides
Serotonergic drug
Naftopidil Naluzotan Nefazodone Niaprazine Oxypertine Pardoprunox pCPP pFPP Posaconazole S-14,506 S-14,671 S-15,535 SB-258,585 SB-271,046 SB-357,134 SB-399,885
Trifluoromethylphenylpiperazine
Trifluoromethylphenylpiperazine
Chemical compound
Naftopidil Naluzotan Nefazodone Niaprazine Oxypertine Pardoprunox pCPP pFPP Posaconazole S-14,506 S-14,671 S-15,535 SB-258,585 SB-271,046 SB-357,134 SB-399,885
Imatinib
Drug used to treat angina
Naftopidil Naluzotan Nefazodone Niaprazine Oxypertine Pardoprunox pCPP pFPP Posaconazole S-14,506 S-14,671 S-15,535 SB-258,585 SB-271,046 SB-357,134 SB-399,885
Ranolazine
Chemical compound
Naftopidil Naluzotan Nefazodone Niaprazine Oxypertine Pardoprunox pCPP pFPP Posaconazole S-14,506 S-14,671 S-15,535 SB-258,585 SB-271,046 SB-357,134 SB-399,885
Pyrimidinylpiperazine
Medication used to treat insomnia
indinavir, itraconazole, ketoconazole, lopinavir, nefazodone, nelfinavir, posaconazole, ritonavir, saquinavir, telaprevir, and telithromycin (concomitant use
Suvorexant
Chemical compound
Naftopidil Naluzotan Nefazodone Niaprazine Oxypertine Pardoprunox pCPP pFPP Posaconazole S-14,506 S-14,671 S-15,535 SB-258,585 SB-271,046 SB-357,134 SB-399,885
Quipazine
Chemical compound
Naftopidil Naluzotan Nefazodone Niaprazine Oxypertine Pardoprunox pCPP pFPP Posaconazole S-14,506 S-14,671 S-15,535 SB-258,585 SB-271,046 SB-357,134 SB-399,885
Levodropropizine
Medication
Naftopidil Naluzotan Nefazodone Niaprazine Oxypertine Pardoprunox pCPP pFPP Posaconazole S-14,506 S-14,671 S-15,535 SB-258,585 SB-271,046 SB-357,134 SB-399,885
Flibanserin
Species of fungus
destructans was sensitive to Amphotericin B, itraconazole, ketoconazole, posaconazole and voriconazole, while the fungus had some resistance to anidulafungin
Pseudogymnoascus_destructans
Species of fungus
as amphotericin B, itraconazole, triazole, voriconazole, fluconazole, posaconazole, and many others. Also, surgical excision can play a role in treatment
Verruconis_gallopava
Medical condition
treatment failure, or fungal resistance, voriconazole (also a triazole) or posaconazole may be considered as alternatives. Special attention must be paid to
Aspergilloma
Chemical compound
Naftopidil Naluzotan Nefazodone Niaprazine Oxypertine Pardoprunox pCPP pFPP Posaconazole S-14,506 S-14,671 S-15,535 SB-258,585 SB-271,046 SB-357,134 SB-399,885
PIPES
Species of fungus
debridement of necrotic tissues, and anti-fungal therapy with drugs such as posaconazole and amphotericin B. Members of the order Mucorales generally infect immunocompromised
Apophysomyces_variabilis
Pharmaceutical compound
Naftopidil Naluzotan Nefazodone Niaprazine Oxypertine Pardoprunox pCPP pFPP Posaconazole S-14,506 S-14,671 S-15,535 SB-258,585 SB-271,046 SB-357,134 SB-399,885
IHCH-6122
Chemical compound
exhibits no toxicity in mouse cells and, unlike the related compounds posaconazole and fluconazole, increasing the dose is not required to maintain anti-parasitic
VNI_(molecule)
Steroid medication
Zenhale fusidic acid Bactirest-M, Dermotil Fusid, Momate-F gentamicin and posaconazole Mometamax Ultra Veterinary use hydroquinone and tretinoin Acnezac-MH
Mometasone
Reverse-transcriptase inhibitor
Naftopidil Naluzotan Nefazodone Niaprazine Oxypertine Pardoprunox pCPP pFPP Posaconazole S-14,506 S-14,671 S-15,535 SB-258,585 SB-271,046 SB-357,134 SB-399,885
Atevirdine
Pharmaceutical drug classification
J02AC01 Fluconazole J02AC02 Itraconazole J02AC03 Voriconazole J02AC04 Posaconazole J02AC05 Isavuconazole J02AC06 Oteseconazole J02AX01 Flucytosine J02AX04
ATC_code_J02
Chemical compound
Naftopidil Naluzotan Nefazodone Niaprazine Oxypertine Pardoprunox pCPP pFPP Posaconazole S-14,506 S-14,671 S-15,535 SB-258,585 SB-271,046 SB-357,134 SB-399,885
Ensaculin
Recreational drug
Naftopidil Naluzotan Nefazodone Niaprazine Oxypertine Pardoprunox pCPP pFPP Posaconazole S-14,506 S-14,671 S-15,535 SB-258,585 SB-271,046 SB-357,134 SB-399,885
Benzylpiperazine
Species of fungus
highly active against C. tropicalis are itraconazole, voriconazole, posaconazole, ravuconazole and isavuconazole. Voriconazole is a new generation from
Candida_tropicalis
Species of fungus
fungal infections. However, some newer drugs, such as voriconazole, posaconazole, and caspofungin, have shown promise in treating this agent. In one study
Aspergillus_terreus
Species of fungus
are resistant to this treatment. Drugs that might also be of help are posaconazole, miltefosine and albaconazole. Albaconazole is in phase III clinical
Lomentospora_prolificans
Chemical compound
Naftopidil Naluzotan Nefazodone Niaprazine Oxypertine Pardoprunox pCPP pFPP Posaconazole S-14,506 S-14,671 S-15,535 SB-258,585 SB-271,046 SB-357,134 SB-399,885
Vardenafil
Species of fungus
marneffei display low MIC's to amphotericin B as well as itraconazole, posaconazole and voriconazole. T. marneffei had been assumed to reproduce exclusively
Talaromyces_marneffei
Medication for motion sickness or vertigo
Naftopidil Naluzotan Nefazodone Niaprazine Oxypertine Pardoprunox pCPP pFPP Posaconazole S-14,506 S-14,671 S-15,535 SB-258,585 SB-271,046 SB-357,134 SB-399,885
Cyclizine
Chemical compound
Naftopidil Naluzotan Nefazodone Niaprazine Oxypertine Pardoprunox pCPP pFPP Posaconazole S-14,506 S-14,671 S-15,535 SB-258,585 SB-271,046 SB-357,134 SB-399,885
Diethylcarbamazine
Species of fungus
vivo and in vitro. Susceptibility to triazoles such as itraconazole, posaconazole and isavuconazole has been seen in R. mackenziei, though a mixture of
Rhinocladiella_mackenziei
Class of chemical compounds
Naftopidil Naluzotan Nefazodone Niaprazine Oxypertine Pardoprunox pCPP pFPP Posaconazole S-14,506 S-14,671 S-15,535 SB-258,585 SB-271,046 SB-357,134 SB-399,885
Substituted_piperazine
English chemist (born 1948)
drug amiodarone, and that it acted synergistically with the azole drug posaconazole. He then began to investigate antibacterial agents. The human pathogen
Eric_Oldfield_(academic)
Pharmaceutical compound
Naftopidil Naluzotan Nefazodone Niaprazine Oxypertine Pardoprunox pCPP pFPP Posaconazole S-14,506 S-14,671 S-15,535 SB-258,585 SB-271,046 SB-357,134 SB-399,885
ZINC000443438219
Cough suppressant drug
Naftopidil Naluzotan Nefazodone Niaprazine Oxypertine Pardoprunox pCPP pFPP Posaconazole S-14,506 S-14,671 S-15,535 SB-258,585 SB-271,046 SB-357,134 SB-399,885
Zipeprol
Chemical compound
Naftopidil Naluzotan Nefazodone Niaprazine Oxypertine Pardoprunox pCPP pFPP Posaconazole S-14,506 S-14,671 S-15,535 SB-258,585 SB-271,046 SB-357,134 SB-399,885
Dasatinib
Species of alga
reported. Some strains have also showed susceptibility to itraconazole and posaconazole. John R. Goldblum (ed.). Foundations in diagnostic pathology. {{cite
Prototheca_wickerhamii
Chemical compound
Naftopidil Naluzotan Nefazodone Niaprazine Oxypertine Pardoprunox pCPP pFPP Posaconazole S-14,506 S-14,671 S-15,535 SB-258,585 SB-271,046 SB-357,134 SB-399,885
Tirilazad
Species of fungus
will control R. microsporus are amphotericin B and triazoles such as posaconazole, it's also occasionally susceptible to itraconazole. Another way to control
Rhizopus_microsporus
Species of fungus
Tropicoporus tropicalis is also found to be highly resistant to caspofungin and posaconazole, two different anti-fungal compounds. Tropicoporus tropicalis is a poroid
Tropicoporus_tropicalis
Medical condition
from long-term and high-dose prednisone. Newer triazole drugs—such as posaconazole or voriconazole—have not yet been studied in-depth through clinical trials
Allergic bronchopulmonary aspergillosis
Allergic_bronchopulmonary_aspergillosis
Species of fungus
itraconazole/voriconazole/posaconazole was observed for some isolates. Most of the time, aggressive therapy (itraconazole or posaconazole as monotherapy or combined
Aspergillus_felis
Medication for treating fungal infections
econazole, miconazole, ketoconazole, while fluconazole, itraconazole, posaconazole and voriconazole fall under the triazole group. Both groups cause substantial
Topical_antifungal
Chemical compound
Naftopidil Naluzotan Nefazodone Niaprazine Oxypertine Pardoprunox pCPP pFPP Posaconazole S-14,506 S-14,671 S-15,535 SB-258,585 SB-271,046 SB-357,134 SB-399,885
Phenylpiperazine
Tropical disease caused by the oomycete Pythium insidiosum
B, terbinafine, itraconazole, fluconazole, ketoconazole, natamycin, posaconazole, voriconazole, prednisone, flucytosine, liposomal nystatin and azithromycin
Pythiosis
Chemical compound
Naftopidil Naluzotan Nefazodone Niaprazine Oxypertine Pardoprunox pCPP pFPP Posaconazole S-14,506 S-14,671 S-15,535 SB-258,585 SB-271,046 SB-357,134 SB-399,885
Para-Chlorophenylpiperazine
Cocaine-like dopamine reuptake inhibitor derived from modafinil
Naftopidil Naluzotan Nefazodone Niaprazine Oxypertine Pardoprunox pCPP pFPP Posaconazole S-14,506 S-14,671 S-15,535 SB-258,585 SB-271,046 SB-357,134 SB-399,885
JJC8-088
Antipsychotic medication
Naftopidil Naluzotan Nefazodone Niaprazine Oxypertine Pardoprunox pCPP pFPP Posaconazole S-14,506 S-14,671 S-15,535 SB-258,585 SB-271,046 SB-357,134 SB-399,885
Clopenthixol
Chemical compound
Naftopidil Naluzotan Nefazodone Niaprazine Oxypertine Pardoprunox pCPP pFPP Posaconazole S-14,506 S-14,671 S-15,535 SB-258,585 SB-271,046 SB-357,134 SB-399,885
Aripiprazole_lauroxil
Chemical compound
Naftopidil Naluzotan Nefazodone Niaprazine Oxypertine Pardoprunox pCPP pFPP Posaconazole S-14,506 S-14,671 S-15,535 SB-258,585 SB-271,046 SB-357,134 SB-399,885
SB-399885
Species of ascomycete fungus
while other antifungal drugs, such as amphotericin B, itraconazole, posaconazole, terbinafine, anidulafungin, caspofungin, micafungin, showed little in
Acrophialophora_fusispora
Chemical compound
Naftopidil Naluzotan Nefazodone Niaprazine Oxypertine Pardoprunox pCPP pFPP Posaconazole S-14,506 S-14,671 S-15,535 SB-258,585 SB-271,046 SB-357,134 SB-399,885
Para-Methoxyphenylpiperazine
Chemical compound
alternative therapies for onychomycosis and superficial fungal infections: posaconazole, fosravuconazole, voriconazole, oteseconazole". International Journal
Oteseconazole
Chemical compound
avoid strong CYP3A4 inhibitors, such as ketoconazole, itraconazole, posaconazole, clarithromycin, nefazodone, ritonavir, saquinavir, nelfinavir, indinavir
Vorapaxar
Species of fungus
resulting in fatal outcome. In addition, another antifungal agent, posaconazole, was able to successfully treat disseminated infection by S. vasiformis
Saksenaea_vasiformis
Species of fungus
corymbifera is most susceptible to the antifungal drug Amphotericin B and Posaconazole, however, negative side effects are possible. These side effects can
Lichtheimia_corymbifera
Class of psychotropic drugs
Naftopidil Naluzotan Nefazodone Niaprazine Oxypertine Pardoprunox pCPP pFPP Posaconazole S-14,506 S-14,671 S-15,535 SB-258,585 SB-271,046 SB-357,134 SB-399,885
Azapirone
Protein-coding gene in humans
anastrozole, fadrozole, bicalutamide, dexmedetomidine, ravuconazole, and posaconazole. Click on genes, proteins and metabolites below to link to respective
CYP27A1
Species of fungus
bertholletiae infection include amphotericin B, itraconazole, voriconazole and posaconazole. However, compared to other Mucorales species, C. bertholletiae has decreased
Cunninghamella_bertholletiae
Pharmaceutical compound
Naftopidil Naluzotan Nefazodone Niaprazine Oxypertine Pardoprunox pCPP pFPP Posaconazole S-14,506 S-14,671 S-15,535 SB-258,585 SB-271,046 SB-357,134 SB-399,885
MK-212
Species of fungus
(2004). "Successful treatment of Fusarium proliferatum pneumonia with posaconazole in a lung transplant recipient". J. Heart Lung Transplant. 23 (12): 1451–1454
Fusarium_proliferatum
Species of fungus
treated with antifungal agents such as amphotericin B, voriconazole and posaconazole. Amphotericin B used to be the most potent antifungal treatment for severe
Exophiala_jeanselmei
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