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Chemical compound
1-Phenylpiperazine (1-PP or PP) is a simple chemical compound and drug featuring a phenyl group bound to a piperazine ring. The suffix ‘-piprazole’ is
Phenylpiperazine
Class of chemical compounds
(TFMCPP; PAL-179) – selective partial serotonin releasing agent 1-Phenylpiperazine (PP) 1-(1-Naphthyl)piperazine (1-NP) 1-(2-Pyrimidinyl)piperazine (1-PP)
Substituted_piperazine
Antidepressant medication
major depressive disorder, anxiety disorders, and insomnia. It is a phenylpiperazine compound of the serotonin antagonist and reuptake inhibitor (SARI)
Trazodone
Class of drug
receptors. The majority of the currently marketed SARIs belong to the phenylpiperazine class of compounds. Commercially available serotonin antagonist and
Serotonin antagonist and reuptake inhibitor
Serotonin_antagonist_and_reuptake_inhibitor
Serotonergic drug
meta-Trifluoromethylphenylpiperazine (TFMPP) is a recreational drug of the phenylpiperazine chemical class and is a substituted piperazine. Usually in combination
Trifluoromethylphenylpiperazine
Trifluoromethylphenylpiperazine
Atypical antidepressant drug
about 1 in every 250,000 to 300,000 patient years. Nefazodone is a phenylpiperazine compound and is related to trazodone. It has been described as a serotonin
Nefazodone
Chemical compound
Antrafenine (Stakane) is a phenylpiperazine derivative drug invented in 1979. It acts as an analgesic and anti-inflammatory drug with similar efficacy
Antrafenine
Index of chemical compounds with the same name
(2,5-DMPP) 3,4-Dimethylphenylpiperazine (3,4-DMPP) Substituted phenylpiperazine This set index article lists chemical compounds articles associated
Dimethylphenylpiperazine
Chemical compound
S-15535 is a phenylpiperazine drug which is a potent and highly selective 5-HT1A receptor ligand that acts as an agonist and antagonist (weak partial agonist)
S-15535
Pharmaceutical compound
GSK-958108 is a serotonergic drug derived from the phenylpiperazine family which acts as a potent and selective 5-HT1A receptor antagonist, and has been
GSK-958108
Chemical compound
Fluprazine (developmental code name DU-27,716) is a drug of the phenylpiperazine family. It is a so-called serenic or antiaggressive agent. It is closely
Fluprazine
Chemical class of organic compounds
related families that are not phenethylamines themselves include phenylpiperazines, benzylpiperazines, and 4-phenylpiperidines. Chemical structures of
Substituted_phenethylamine
Index of chemical compounds with the same molecular formula
23 g/mol, exact mass: 162.1157 u) may refer to: Anabasine Nicotine Phenylpiperazine Rivanicline This set index page lists chemical structure articles associated
C10H14N2
Chemical compound
Lorpiprazole (INN; brand name Normarex) is an anxiolytic drug of the phenylpiperazine group. It has been described as a serotonin antagonist and reuptake
Lorpiprazole
Pharmaceutical compound
para-chlorophenylpiperazine, is a monoamine releasing agent of the phenylpiperazine family. It acts specifically as a selective partial serotonin releasing
3-Trifluoromethyl-4-chlorophenylpiperazine
3-Trifluoromethyl-4-chlorophenylpiperazine
Class of chemical compounds in which a phenyl group is directly attached to piperidine
derivatives as well. 2-Phenylpiperidine 3-Phenylpiperidine Benzylpiperidine Phenylpiperazine Janssen, PA (April 1962). "A Review of the Chemical Features Associated
Phenylpiperidines
Serotonergic drug
(2-MeOPP), is a phenylpiperazine derivative which is known to act as a serotonergic agent. Along with various other phenylpiperazines, like benzylpiperazine
Ortho-Methoxyphenylpiperazine
Class of CNS depressant drugs
Alkylamines Cycloalkylaminopropanes Arylpiperazines Benzylpiperazines Phenylpiperazines Phenethylamines Aminorexes/phenyloxazolamines Amphetamines/α-methylphenethylamines
Benzodiazepine
Central nervous system stimulant prodrug
phenylbutenamine) Phenylalkynylamines (e.g., phenylbutynamine) Phenylpiperazines (e.g., 1-phenylpiperazine, mCPPTooltip meta-chlorophenylpiperazine, TFMPPTooltip
Lisdexamfetamine
Class of medications
Sanofi-Synthélabo Aripiprazole Phenylpiperazine/Quinolinone Atypical Abilify 2002 Otsuka/Bristol-Myers Squibb Aripiprazole lauroxil Phenylpiperazine/Quinolinone Atypical
Antipsychotic
Chemical compound
1-naphthylaminopropane (1-NAP), 2-naphthylaminopropane (2-NAP), 1-phenylpiperazine (1-PP), 6-ABTooltip 6-amino-6,7,8,9-tetrahydro-5H-benzocycloheptene
2-Aminotetralin
Obsolete sedative–hypnotic drug
Alkylamines Cycloalkylaminopropanes Arylpiperazines Benzylpiperazines Phenylpiperazines Phenethylamines Aminorexes/phenyloxazolamines Amphetamines/α-methylphenethylamines
Methaqualone
Antihistamine medication
olanzapine, paliperidone, quetiapine, risperidone, ziprasidone, zotepine) Phenylpiperazine antidepressants (e.g., hydroxynefazodone, nefazodone, trazodone, triazoledione)
Cetirizine
Class of compounds
A serotonin releasing agent (SRA) is a type of drug that induces the release of serotonin into the neuronal synaptic cleft. A selective serotonin releasing
Serotonin_releasing_agent
Antidepressant medication
condensation reaction between 2-chloro-3-cyanopyridine (1) and 1-methyl-3-phenylpiperazine (2) to give cyano compound 3. Hydrolysis of the cyanide group to the
Mirtazapine
Medication mainly used for depression and smoking cessation
phenylbutenamine) Phenylalkynylamines (e.g., phenylbutynamine) Phenylpiperazines (e.g., 1-phenylpiperazine, mCPPTooltip meta-chlorophenylpiperazine, TFMPPTooltip
Bupropion
Pharmaceutical compound
SDZ 216-525 is a serotonergic drug derived from the phenylpiperazine family which is used in scientific research. It acts as a potent and selective 5-HT1A
SDZ_216-525
Species of plant
Alkylamines Cycloalkylaminopropanes Arylpiperazines Benzylpiperazines Phenylpiperazines Phenethylamines Aminorexes/phenyloxazolamines Amphetamines/α-methylphenethylamines
Mitragyna_speciosa
Chemical compound
para-Chlorophenylpiperazine (pCPP) is a psychoactive drug of the phenylpiperazine class. It is relatively obscure, with limited human use, and produces
Para-Chlorophenylpiperazine
Muscle relaxant medication
Pardoprunox Pelanserin Perlapine Phendioxan Phenoxybenzamine Phentolamine Phenylpiperazine antidepressants (e.g., hydroxynefazodone, nefazodone, trazodone, triazoledione)
Cyclobenzaprine
Chemical compound
1-naphthylaminopropane (1-NAP), 2-naphthylaminopropane (2-NAP), 1-phenylpiperazine (1-PP), 6-ABTooltip 6-amino-6,7,8,9-tetrahydro-5H-benzocycloheptene
2-Amino-1,2-dihydronaphthalene
2-Amino-1,2-dihydronaphthalene
Psychoactive drug, often called ecstasy
phenylbutenamine) Phenylalkynylamines (e.g., phenylbutynamine) Phenylpiperazines (e.g., 1-phenylpiperazine, mCPPTooltip meta-chlorophenylpiperazine, TFMPPTooltip
MDMA
Chemical compound
Hydroxynefazodone is a phenylpiperazine compound and a major metabolite of the antidepressant nefazodone. It has similar biological activity and a similar
Hydroxynefazodone
SNRI antidepressant
phenylbutenamine) Phenylalkynylamines (e.g., phenylbutynamine) Phenylpiperazines (e.g., 1-phenylpiperazine, mCPPTooltip meta-chlorophenylpiperazine, TFMPPTooltip
Venlafaxine
Beta blocker drug
Pardoprunox Pelanserin Perlapine Phendioxan Phenoxybenzamine Phentolamine Phenylpiperazine antidepressants (e.g., hydroxynefazodone, nefazodone, trazodone, triazoledione)
Propranolol
Serotonergic drug
meta-Chlorophenylpiperazine (mCPP) is a psychoactive drug of the phenylpiperazine family. It was initially developed in the late-1970s and used in scientific
Meta-Chlorophenylpiperazine
Central nervous system stimulant
Alkylamines Cycloalkylaminopropanes Arylpiperazines Benzylpiperazines Phenylpiperazines Phenethylamines Aminorexes/phenyloxazolamines Amphetamines/α-methylphenethylamines
Caffeine
Chemical compound
phenylbutenamine) Phenylalkynylamines (e.g., phenylbutynamine) Phenylpiperazines (e.g., 1-phenylpiperazine, mCPPTooltip meta-chlorophenylpiperazine, TFMPPTooltip
Adrenochrome
Psychedelic drug
phenylbutenamine) Phenylalkynylamines (e.g., phenylbutynamine) Phenylpiperazines (e.g., 1-phenylpiperazine, mCPPTooltip meta-chlorophenylpiperazine, TFMPPTooltip
2C-B
Class of depressant drugs derived from barbituric acid
precursors (tryptophan, 5-hydroxytryptophan (5-HTP; oxitriptan)) Phenylpiperazines (e.g., trazodone, niaprazine) Theanine Tributyrin Tricyclic antidepressants
Barbiturate
Tropane alkaloid and stimulant drug
Alkylamines Cycloalkylaminopropanes Arylpiperazines Benzylpiperazines Phenylpiperazines Phenethylamines Aminorexes/phenyloxazolamines Amphetamines/α-methylphenethylamines
Cocaine
Antipsychotic drug
DU-29840 and DU-29894) is an experimental antipsychotic drug of the phenylpiperazine family which was under development for the treatment of psychotic disorders
Elopiprazole
Medication used to treat anxiety disorders
Pardoprunox Pelanserin Perlapine Phendioxan Phenoxybenzamine Phentolamine Phenylpiperazine antidepressants (e.g., hydroxynefazodone, nefazodone, trazodone, triazoledione)
Buspirone
Gamma-aminobutyric acid analog
Alkylamines Cycloalkylaminopropanes Arylpiperazines Benzylpiperazines Phenylpiperazines Phenethylamines Aminorexes/phenyloxazolamines Amphetamines/α-methylphenethylamines
Gabapentin
Central nervous system stimulant
phenylbutenamine) Phenylalkynylamines (e.g., phenylbutynamine) Phenylpiperazines (e.g., 1-phenylpiperazine, mCPPTooltip meta-chlorophenylpiperazine, TFMPPTooltip
Methamphetamine
Type of α-amino acid
phenylbutenamine) Phenylalkynylamines (e.g., phenylbutynamine) Phenylpiperazines (e.g., 1-phenylpiperazine, mCPPTooltip meta-chlorophenylpiperazine, TFMPPTooltip
Phenylalanine
Recreational drug
phenylbutenamine) Phenylalkynylamines (e.g., phenylbutynamine) Phenylpiperazines (e.g., 1-phenylpiperazine, mCPPTooltip meta-chlorophenylpiperazine, TFMPPTooltip
Mephedrone
Chemical compound
metabolize to 1-PP either. Substituted piperazine Pyridinylpiperazine Phenylpiperazine Diphenylmethylpiperazine Benzylpiperazine Blier P, Curet O, Chaput
Pyrimidinylpiperazine
Beta-lactam antibiotic
phenylbutenamine) Phenylalkynylamines (e.g., phenylbutynamine) Phenylpiperazines (e.g., 1-phenylpiperazine, mCPPTooltip meta-chlorophenylpiperazine, TFMPPTooltip
Amoxicillin
Substance that arouses sexual desires
Alkylamines Cycloalkylaminopropanes Arylpiperazines Benzylpiperazines Phenylpiperazines Phenethylamines Aminorexes/phenyloxazolamines Amphetamines/α-methylphenethylamines
Aphrodisiac
Chemical compound
olanzapine, paliperidone, quetiapine, risperidone, ziprasidone, zotepine) Phenylpiperazine antidepressants (e.g., hydroxynefazodone, nefazodone, trazodone, triazoledione)
Meclizine
Atypical antipsychotic medication
Perospirone Risperidone# Ziprasidone Butyrophenones: Lumateperone Phenylpiperazines/quinolinones: Aripiprazole Aripiprazole lauroxil Brilaroxazine† Brexpiprazole
Quetiapine
Perospirone Risperidone# Ziprasidone Butyrophenones: Lumateperone Phenylpiperazines/quinolinones: Aripiprazole Aripiprazole lauroxil Brilaroxazine† Brexpiprazole
List_of_antidepressants
Comprehensive list of compounds structurally related to fentanyl
Alkylamines Cycloalkylaminopropanes Arylpiperazines Benzylpiperazines Phenylpiperazines Phenethylamines Aminorexes/phenyloxazolamines Amphetamines/α-methylphenethylamines
List_of_fentanyl_analogues
Index of chemical compounds with the same name
Alkylamines Cycloalkylaminopropanes Arylpiperazines Benzylpiperazines Phenylpiperazines Phenethylamines Aminorexes/phenyloxazolamines Amphetamines/α-methylphenethylamines
Methylxanthines
Antihistamine medication
olanzapine, paliperidone, quetiapine, risperidone, ziprasidone, zotepine) Phenylpiperazine antidepressants (e.g., hydroxynefazodone, nefazodone, trazodone, triazoledione)
Loratadine
Beta blocker medication
Pardoprunox Pelanserin Perlapine Phendioxan Phenoxybenzamine Phentolamine Phenylpiperazine antidepressants (e.g., hydroxynefazodone, nefazodone, trazodone, triazoledione)
Metoprolol
Chemical compound
Naluzotan (INN, USAN; PRX-00023) is a serotonergic drug of the phenylpiperazine class that was under investigation by EPIX Pharmaceuticals Inc for the
Naluzotan
Psychoactive drug taken by mouth
phenylbutenamine) Phenylalkynylamines (e.g., phenylbutynamine) Phenylpiperazines (e.g., 1-phenylpiperazine, mCPPTooltip meta-chlorophenylpiperazine, TFMPPTooltip
(R)-MDMA
Pharmaceutical compound
(pNPP; code name PAL-175) is a monoamine releasing agent of the phenylpiperazine family. It acts specifically as a selective partial serotonin releasing
Para-Nitrophenylpiperazine
Antihistamine medication
olanzapine, paliperidone, quetiapine, risperidone, ziprasidone, zotepine) Phenylpiperazine antidepressants (e.g., hydroxynefazodone, nefazodone, trazodone, triazoledione)
Fexofenadine
Central nervous system stimulant
phenylbutenamine) Phenylalkynylamines (e.g., phenylbutynamine) Phenylpiperazines (e.g., 1-phenylpiperazine, mCPPTooltip meta-chlorophenylpiperazine, TFMPPTooltip
Methylphenidate
Chemical compound
Mepiprazole (INN, BAN; brand name Psigodal) is an anxiolytic drug of the phenylpiperazine group with additional antidepressant properties that is marketed in
Mepiprazole
Class of drugs
Alkylamines Cycloalkylaminopropanes Arylpiperazines Benzylpiperazines Phenylpiperazines Phenethylamines Aminorexes/phenyloxazolamines Amphetamines/α-methylphenethylamines
Nitazenes
Naturally occurring psychedelic compound
phenylbutenamine) Phenylalkynylamines (e.g., phenylbutynamine) Phenylpiperazines (e.g., 1-phenylpiperazine, mCPPTooltip meta-chlorophenylpiperazine, TFMPPTooltip
Mescaline
Chemical compound
1970s and either is no longer marketed or was never marketed. It is a phenylpiperazine related to trazodone and nefazodone in chemical structure and is a
Etoperidone
Species of flowering plant
precursors (tryptophan, 5-hydroxytryptophan (5-HTP; oxitriptan)) Phenylpiperazines (e.g., trazodone, niaprazine) Theanine Tributyrin Tricyclic antidepressants
Valerian_(herb)
Fluoroquinolone antibiotic
v t e Arylpiperazines Phenylpiperazines 1-Phenylpiperazine (1-PP; PP) 3,4-CFP 2C-B-PP Acaprazine Antrafenine Aripiprazole Batoprazine Bifeprunox BRL-15
Ciprofloxacin
Tricyclic antidepressant
precursors (tryptophan, 5-hydroxytryptophan (5-HTP; oxitriptan)) Phenylpiperazines (e.g., trazodone, niaprazine) Theanine Tributyrin Tricyclic antidepressants
Amitriptyline
Pharmaceutical compound
2-bromophenylpiperazine (2-BPP), is a monoamine releasing agent of the phenylpiperazine family. It acts as a serotonin–norepinephrine–dopamine releasing agent
Ortho-Bromophenylpiperazine
Muscle relaxant medication
precursors (tryptophan, 5-hydroxytryptophan (5-HTP; oxitriptan)) Phenylpiperazines (e.g., trazodone, niaprazine) Theanine Tributyrin Tricyclic antidepressants
Baclofen
Medication used to treat mental disorders
Alkylamines Cycloalkylaminopropanes Arylpiperazines Benzylpiperazines Phenylpiperazines Phenethylamines Aminorexes/phenyloxazolamines Amphetamines/α-methylphenethylamines
Psychiatric_medication
Chemical compound
Graham Chen and his co-workers at Parke, Davis & Co. (Now Pfizer) Phenylpiperazine Prado WA, Segalla DK (August 2004). "Antinociceptive effects of bethanechol
Dimethylphenylpiperazinium
Chemical compound
olanzapine, paliperidone, quetiapine, risperidone, ziprasidone, zotepine) Phenylpiperazine antidepressants (e.g., hydroxynefazodone, nefazodone, trazodone, triazoledione)
Betahistine
Compound intended to improve cognitive function
Alkylamines Cycloalkylaminopropanes Arylpiperazines Benzylpiperazines Phenylpiperazines Phenethylamines Aminorexes/phenyloxazolamines Amphetamines/α-methylphenethylamines
Nootropic
Chemical compound which aids breathing
Pardoprunox Pelanserin Perlapine Phendioxan Phenoxybenzamine Phentolamine Phenylpiperazine antidepressants (e.g., hydroxynefazodone, nefazodone, trazodone, triazoledione)
Clenbuterol
Class of medications used to alleviate anxiety
Alkylamines Cycloalkylaminopropanes Arylpiperazines Benzylpiperazines Phenylpiperazines Phenethylamines Aminorexes/phenyloxazolamines Amphetamines/α-methylphenethylamines
Anxiolytic
Dried latex of the opium poppy containing narcotic compounds
Alkylamines Cycloalkylaminopropanes Arylpiperazines Benzylpiperazines Phenylpiperazines Phenethylamines Aminorexes/phenyloxazolamines Amphetamines/α-methylphenethylamines
Opium
Medication
Perospirone Risperidone# Ziprasidone Butyrophenones: Lumateperone Phenylpiperazines/quinolinones: Aripiprazole Aripiprazole lauroxil Brilaroxazine† Brexpiprazole
Xanomeline/trospium_chloride
Antihistamine medication
olanzapine, paliperidone, quetiapine, risperidone, ziprasidone, zotepine) Phenylpiperazine antidepressants (e.g., hydroxynefazodone, nefazodone, trazodone, triazoledione)
Diphenhydramine
Hormone and medication
phenylbutenamine) Phenylalkynylamines (e.g., phenylbutynamine) Phenylpiperazines (e.g., 1-phenylpiperazine, mCPPTooltip meta-chlorophenylpiperazine, TFMPPTooltip
Adrenaline
Chemical compound
3-Chloro-4-fluorophenylpiperazine (3,4-CFP, Kleferein) is a psychoactive drug of the phenylpiperazine class. It has been sold as a designer drug, first being identified
3-Chloro-4-fluorophenylpiperazine
3-Chloro-4-fluorophenylpiperazine
Alkylamines Cycloalkylaminopropanes Arylpiperazines Benzylpiperazines Phenylpiperazines Phenethylamines Aminorexes/phenyloxazolamines Amphetamines/α-methylphenethylamines
Utopioid_(drug_class)
Atypical antipsychotic
Perospirone Risperidone# Ziprasidone Butyrophenones: Lumateperone Phenylpiperazines/quinolinones: Aripiprazole Aripiprazole lauroxil Brilaroxazine† Brexpiprazole
Lumateperone
Antihistamine drug
Pardoprunox Pelanserin Perlapine Phendioxan Phenoxybenzamine Phentolamine Phenylpiperazine antidepressants (e.g., hydroxynefazodone, nefazodone, trazodone, triazoledione)
Hydroxyzine
Drug mixture used mainly to treat ADHD and narcolepsy
phenylbutenamine) Phenylalkynylamines (e.g., phenylbutynamine) Phenylpiperazines (e.g., 1-phenylpiperazine, mCPPTooltip meta-chlorophenylpiperazine, TFMPPTooltip
Adderall
Pharmaceutical compound
olanzapine, paliperidone, quetiapine, risperidone, ziprasidone, zotepine) Phenylpiperazine antidepressants (e.g., hydroxynefazodone, nefazodone, trazodone, triazoledione)
Seliforant
CNS depressant medication
precursors (tryptophan, 5-hydroxytryptophan (5-HTP; oxitriptan)) Phenylpiperazines (e.g., trazodone, niaprazine) Theanine Tributyrin Tricyclic antidepressants
Phenibut
Veterinary antipsychotic
Mafoprazine is an antipsychotic of the phenylpiperazine class which is used in veterinary medicine. Intramuscular injections of mafoprazine mesylate are
Mafoprazine
Muscle relaxant medication
precursors (tryptophan, 5-hydroxytryptophan (5-HTP; oxitriptan)) Phenylpiperazines (e.g., trazodone, niaprazine) Theanine Tributyrin Tricyclic antidepressants
Tizanidine
Insomnia medication
precursors (tryptophan, 5-hydroxytryptophan (5-HTP; oxitriptan)) Phenylpiperazines (e.g., trazodone, niaprazine) Theanine Tributyrin Tricyclic antidepressants
Lemborexant
Chemical compound
phenylbutenamine) Phenylalkynylamines (e.g., phenylbutynamine) Phenylpiperazines (e.g., 1-phenylpiperazine, mCPPTooltip meta-chlorophenylpiperazine, TFMPPTooltip
5-MAPB
Medication that reduces stomach acid
olanzapine, paliperidone, quetiapine, risperidone, ziprasidone, zotepine) Phenylpiperazine antidepressants (e.g., hydroxynefazodone, nefazodone, trazodone, triazoledione)
Famotidine
Disorder causing trouble with sleeping
precursors (tryptophan, 5-hydroxytryptophan (5-HTP; oxitriptan)) Phenylpiperazines (e.g., trazodone, niaprazine) Theanine Tributyrin Tricyclic antidepressants
Insomnia
Veterinary anesthetic, sedative and analgesic
Pardoprunox Pelanserin Perlapine Phendioxan Phenoxybenzamine Phentolamine Phenylpiperazine antidepressants (e.g., hydroxynefazodone, nefazodone, trazodone, triazoledione)
Xylazine
Psychiatric medication used to treat mood disorders
Alkylamines Cycloalkylaminopropanes Arylpiperazines Benzylpiperazines Phenylpiperazines Phenethylamines Aminorexes/phenyloxazolamines Amphetamines/α-methylphenethylamines
Mood_stabilizer
Pharmaceutical compound
phenylbutenamine) Phenylalkynylamines (e.g., phenylbutynamine) Phenylpiperazines (e.g., 1-phenylpiperazine, mCPPTooltip meta-chlorophenylpiperazine, TFMPPTooltip
2,4,5-Trimethoxyamphetamine
Drug that reduces excitement without inducing sleep
Alkylamines Cycloalkylaminopropanes Arylpiperazines Benzylpiperazines Phenylpiperazines Phenethylamines Aminorexes/phenyloxazolamines Amphetamines/α-methylphenethylamines
Sedative
Chemical compound
olanzapine, paliperidone, quetiapine, risperidone, ziprasidone, zotepine) Phenylpiperazine antidepressants (e.g., hydroxynefazodone, nefazodone, trazodone, triazoledione)
Bufenadrine
Drug that increases wakefulness
Alkylamines Cycloalkylaminopropanes Arylpiperazines Benzylpiperazines Phenylpiperazines Phenethylamines Aminorexes/phenyloxazolamines Amphetamines/α-methylphenethylamines
Wakefulness-promoting_agent
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