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Organic compound containing C–PO(OR)2 groups
In organic chemistry, phosphonates or phosphonic acids are organophosphorus compounds containing C−PO(OR)2 groups, where R is an organic group (alkyl,
Phosphonate
Chemical synthesis of nucleic acids
pioneered H-phosphonate and phosphate triester methods of oligonucleotide synthesis. The reaction of compounds 1 and 2 to form H-phosphonate diester 3 is
Oligonucleotide_synthesis
In enzymology, a phosphonate dehydrogenase (EC 1.20.1.1) is an enzyme that catalyzes the chemical reaction phosphonate + NAD+ + H2O ⇌ {\displaystyle \rightleftharpoons
Phosphonate_dehydrogenase
Variation on the Wittig chemical reaction
reaction is a chemical reaction used in organic chemistry of stabilized phosphonate carbanions with aldehydes (or ketones) to produce predominantly E-alkenes
Horner–Wadsworth–Emmons reaction
Horner–Wadsworth–Emmons_reaction
Type of metal-organic framework compound
Metal phosphonates are coordination compounds in which metal ions or metal clusters are coordinated by phosphonates. They are characterized by a highly
Metal_phosphonate
Organic compound with at least one covalent carbon–phosphorus bond
from which they are derived. Phosphonates are esters of phosphonic acid and have the general formula RP(=O)(OR')2. Phosphonates have many technical applications
Organophosphorus_chemistry
Class of medications used primarily to treat high blood pressure
Angiotensin-converting-enzyme inhibitors (ACE inhibitors) are a class of medication used primarily for the treatment of high blood pressure and heart failure
ACE_inhibitor
Antiviral drug
Cidofovir, brand name Vistide, is a topical or injectable antiviral medication primarily used as a treatment for cytomegalovirus (CMV) retinitis (an infection
Cidofovir
Compound derived from an acid
esters, e.g. triethyl phosphite (P(−O−CH2CH3)3), and phosphonate esters, e.g. diethyl phosphonate (H−P(=O)(−O−CH2CH3)2) Some inorganic acids that are unstable
Ester
Chemical compound
Disodium hydrogen phosphite Names IUPAC name sodium phosphonate pentahydrate Other names Sodium phosphate dibasic pentahydrate, sodium phosphite Identifiers
Disodium_hydrogen_phosphite
Enzyme
focused on α-biphenylsulfonylamino phosphonates. These inhibitors bind through two phosphonate oxygen atoms. Phosphonate inhibitors have been developed that
Metalloprotease_inhibitor
Enzyme
In enzymology, a phosphonate-transporting ATPase (EC 3.6.3.28) is an enzyme that catalyzes the chemical reaction ATP + H2O + phosphonateout ⇌ {\displaystyle
Phosphonate-transporting ATPase
Phosphonate-transporting_ATPase
Chemical compound (H3PO3)
phosphite ion. (Note that the IUPAC recommendations are hydrogen phosphonate and phosphonate respectively). The hydrogen atom bonded directly to the phosphorus
Phosphorous_acid
Ion
Correspondingly, the IUPAC-recommended name for the HPO2− 3 ion is phosphonate. In the US the IUPAC naming conventions for inorganic compounds are taught
Phosphite_(ion)
Chemical compound
dimethyl (diazomethyl)phosphonate 2 and potassium tert-butoxide to give substituted alkynes 3. Dimethyl (diazomethyl)phosphonate 2 is often called the
Seyferth–Gilbert_homologation
Industrial water treatment chemical
polymeric AS and natural green AS. Common active ingredients include phosphonates, polyphosphates, polymers, aminophosphonates and organic acids. Antiscalants
Antiscalant
Antiviral drug used to treat or prevent HIV and hepatitis infections
is analogous to a triphosphate, as tenofovir itself already has one phosphonate residue), the active compound that inhibits reverse transcriptase via
Tenofovir_disoproxil
Chemical compound
phosphonic acid. It has chelating and anti corrosion properties. EDTMP is the phosphonate analog of EDTA. It is classified as a nitrogenous organic polyphosphonic
EDTMP
Chemical reaction
hydrogen (thio)phosphonate with a base, followed by a nucleophilic substitution of phosphorus on a haloalkane, to give an alkyl (thio)phosphonate. Yields of
Michaelis–Becker_reaction
Chemical reaction
α-aminomethylphosphonates from an amine, a carbonyl compound, and a dialkyl phosphonate, (RO)2P(O)H (that are also called dialkylphosphites). Aminophosphonates
Kabachnik–Fields_reaction
Species of bacterium
Streptomyces. Streptomyces regensis produces actinomycin and cyanohydrin phosphonate. List of Streptomyces species LPSN bacterio.net UniProt Deutsche Sammlung
Streptomyces_regensis
Chemical compound
as 1-hydroxyethylidene-1,1-diphosphoic acid (HEDP), it is a versatile phosphonate compound known for its corrosion inhibition, chelating, and stabilizing
Etidronic_acid
InterPro Family
(2-aminoethyl)phosphonate:pyruvate aminotransferase. Other names in common use include (2-aminoethyl)phosphonate transaminase, (2-aminoethyl)phosphonate aminotransferase
2-aminoethylphosphonate—pyruvate transaminase
2-aminoethylphosphonate—pyruvate_transaminase
Drugs used to treat bone disorders
optimizing the structure of the R2 group to best inhibit bone resorption. Phosphonate groups in the chemical structure are important for the binding of the
Discovery and development of bisphosphonates
Discovery_and_development_of_bisphosphonates
Class of organophosphates; classified as weapons of mass destruction
multiwavelength LPAS: dimethyl methyl phosphonate (DMMP) diethyl methyl phosphonate (DEMP)[citation needed] diisopropyl methyl phosphonate (DIMP) dimethylpolysiloxane
Nerve_agent
Pharmaceutical drugs for preventing bone loss
refers to the presence two phosphonate (PO2(OH)−) groups. They are also called diphosphonates (bis- or di- + phosphonate). The PO2(OH)− groups readily
Bisphosphonate
Systemic herbicide and crop desiccant
and crop desiccant. It is an organophosphorus compound, specifically a phosphonate, which acts by inhibiting the plant enzyme 5-enolpyruvylshikimate-3-phosphate
Glyphosate
Chemical reaction
undergoing the Arbuzov reaction; phosphite esters (1) react to form phosphonates (2), phosphonites (3) react to form phosphinates (4) and phosphinites
Michaelis–Arbuzov_reaction
Organic compounds of the form >C=O
Silether Silole Silatrane Silicate Phosphorus Phosphate Phosphodiester Phosphonate Phosphite Phosphonous Phosphinate Phosphine oxide Phosphine Phosphonium
Ketone
Conversions of trialkyl to α-hydroxy phosphonates
Abramov reaction is the related conversions of trialkyl to α-hydroxy phosphonates by the addition to carbonyl compounds. In terms of mechanism, the reaction
Abramov_reaction
Organic compound containing the functional group R–CH=O
reagent Ohira–Bestmann reaction Alkyne Reagent: dimethyl (diazomethyl)phosphonate Johnson–Corey–Chaykovsky reaction Epoxide Reagent: a sulfonium ylide
Aldehyde
Chemical compound
lexidronam (chemical name Samarium-153-ethylene diamine tetramethylene phosphonate, abbreviated Samarium-153 EDTMP, trade name Quadramet) is a chelated
Samarium_(153Sm)_lexidronam
Organic compound
Silether Silole Silatrane Silicate Phosphorus Phosphate Phosphodiester Phosphonate Phosphite Phosphonous Phosphinate Phosphine oxide Phosphine Phosphonium
Urea
Chemical compound
Silether Silole Silatrane Silicate Phosphorus Phosphate Phosphodiester Phosphonate Phosphite Phosphonous Phosphinate Phosphine oxide Phosphine Phosphonium
Glycidamide
Chemical compound
Diphenyl phosphite Names Preferred IUPAC name Diphenyl phosphonate Other names Phosphonic acid, diphenyl ester Identifiers CAS Number 4712-55-4 Y 3D model
Diphenyl_phosphite
Class of enzymes
import of phosphonate and organophosphate anions. ATP + H2O + phosphonate [phosphonate-binding protein][side 1] = ADP + phosphate + phosphonate [side 2]
Translocase
aldehydes and ketones, β-amino ketones, α-amino phosphonates, aziridine 2-carboxylates, and aziridine 2-phosphonates. Many of these same transformations can be
N-Sulfinyl_imine
and the phosphonate analogue of oseltamivir has been reported to show stronger activity resulted from a pertinent binding mode of phosphonate with three
Discovery and development of neuraminidase inhibitors
Discovery_and_development_of_neuraminidase_inhibitors
Chemical compound
being named as a phosphite the compound exists overwhelmingly in its phosphonate form, (C2H5O)2P(O)H, a property it shares with its parent acid phosphorous
Diethyl_phosphite
Organic compounds of the form >C=N–OH
reactivate acetylcholinesterase by attaching to phosphorus, forming an oxime-phosphonate, which then splits away from the acetylcholinesterase molecule. Oxime
Oxime
Chemical compound
apartheid-era South African chemical weapons program Project Coast. EA-1370 is a phosphonate analogue, isopropyl para-nitrophenyl methylphosphonate, the junction
Paraoxon
Chemical compound
Diisopropyl methylphosphonate (DIMP), also known as diisopropyl methane-phosphonate and phosphonic acid and methyl-bis-(1-methylethyl)ester, is a chemical
Diisopropyl_methylphosphonate
Type of organosulfur compound
Silether Silole Silatrane Silicate Phosphorus Phosphate Phosphodiester Phosphonate Phosphite Phosphonous Phosphinate Phosphine oxide Phosphine Phosphonium
Sulfinylamine
Chemical compound
known as GD-7, is an organophosphate nerve agent of the V-series, the phosphonate analog of the organophosphate insecticide demeton. EA-5478 is the pinacolyl
V-sub_x
1992 aircraft accident in the Netherlands
Parragon. ISBN 9781445410968. "Nerve Agent Precursor: Dimethyl Methyl Phosphonate". Archived from the original on 4 September 2013. Van Den Burg, Harm;
El_Al_Flight_1862
Chemical reaction
Silether Silole Silatrane Silicate Phosphorus Phosphate Phosphodiester Phosphonate Phosphite Phosphonous Phosphinate Phosphine oxide Phosphine Phosphonium
Hydrodealkylation
Chemical compound
environments DTPMPA has better scale and corrosion inhibition effect than other phosphonates. Detergents and cleaning agents Water treatment Scaling inhibitor Chelating
DTPMP
Organic compounds of the form RC(=O)NR′R″
Silether Silole Silatrane Silicate Phosphorus Phosphate Phosphodiester Phosphonate Phosphite Phosphonous Phosphinate Phosphine oxide Phosphine Phosphonium
Amide
Czech research institute
medicinal chemistry. Its most significant results are acyclic nucleotide phosphonate antivirals (ANPs) discovered by Antonín Holý at IOCB in collaboration
Institute of Organic Chemistry and Biochemistry
Institute_of_Organic_Chemistry_and_Biochemistry
Any organic compound having a sulfanyl group (–SH)
Silether Silole Silatrane Silicate Phosphorus Phosphate Phosphodiester Phosphonate Phosphite Phosphonous Phosphinate Phosphine oxide Phosphine Phosphonium
Thiol
Organic compounds with a diazenyl group (–N=N–)
Silether Silole Silatrane Silicate Phosphorus Phosphate Phosphodiester Phosphonate Phosphite Phosphonous Phosphinate Phosphine oxide Phosphine Phosphonium
Azo_compound
Series of nerve agents developed by the Soviet Union
P=Se), which is most commonly depicted as being a phosphoramidate or phosphonate, usually fluorinated (cf. monofluorophosphate). The organic groups are
Novichok
Type of fungus
first heavy snow. Fungicides may include benzimidazole, strobilurin, and phosphonate fungicides. However, it has been found that some pink snow molds are
Snow_mold
Chemical group (–CH2–C6H5)
Silether Silole Silatrane Silicate Phosphorus Phosphate Phosphodiester Phosphonate Phosphite Phosphonous Phosphinate Phosphine oxide Phosphine Phosphonium
Benzyl_group
Chemical compounds and groups containing nitrogen with a lone pair (:N)
Silether Silole Silatrane Silicate Phosphorus Phosphate Phosphodiester Phosphonate Phosphite Phosphonous Phosphinate Phosphine oxide Phosphine Phosphonium
Amine
Chemical compound
334. Arthur F. Kluge (1990). "Diethyl [(2-Tetrahydropyranyloxy)methyl]phosphonate". Organic Syntheses; Collected Volumes, vol. 7, p. 160. Wuts, Peter G
3,4-Dihydropyran
Chemical compounds with the structure R–O–O–R'
Silether Silole Silatrane Silicate Phosphorus Phosphate Phosphodiester Phosphonate Phosphite Phosphonous Phosphinate Phosphine oxide Phosphine Phosphonium
Peroxide
Chemical group (>N–C(=O)–O–)
Silether Silole Silatrane Silicate Phosphorus Phosphate Phosphodiester Phosphonate Phosphite Phosphonous Phosphinate Phosphine oxide Phosphine Phosphonium
Carbamate
Chemical group derived from alkanes (one hydrogen removed)
Silether Silole Silatrane Silicate Phosphorus Phosphate Phosphodiester Phosphonate Phosphite Phosphonous Phosphinate Phosphine oxide Phosphine Phosphonium
Alkyl_group
Nucleosides must be triphosphorylated, while nucleotides, which possess one phosphonated group, must be diphosphorylated. This stepwise activation process occurs
Discovery and development of nucleoside and nucleotide reverse-transcriptase inhibitors
Discovery_and_development_of_nucleoside_and_nucleotide_reverse-transcriptase_inhibitors
Chemical group (–OC(O)CH3)
Silether Silole Silatrane Silicate Phosphorus Phosphate Phosphodiester Phosphonate Phosphite Phosphonous Phosphinate Phosphine oxide Phosphine Phosphonium
Acetoxy_group
Class of chemical compounds
Silether Silole Silatrane Silicate Phosphorus Phosphate Phosphodiester Phosphonate Phosphite Phosphonous Phosphinate Phosphine oxide Phosphine Phosphonium
Hydroperoxide
334. Arthur F. Kluge (1990). "Diethyl [(2-Tetrahydropyranyloxy)methyl]phosphonate". Organic Syntheses; Collected Volumes, vol. 7, p. 160. Haugan, Jarle
List_of_reagents
Organosulfur compounds of the form R–SC(=O)–R′
Silether Silole Silatrane Silicate Phosphorus Phosphate Phosphodiester Phosphonate Phosphite Phosphonous Phosphinate Phosphine oxide Phosphine Phosphonium
Thioester
Organic compounds made of alkyl/aryl groups bound to oxygen (R–O–R')
Silether Silole Silatrane Silicate Phosphorus Phosphate Phosphodiester Phosphonate Phosphite Phosphonous Phosphinate Phosphine oxide Phosphine Phosphonium
Ether
Salt that is a metal-thioate/O-esters of dithiocarbonate
Silether Silole Silatrane Silicate Phosphorus Phosphate Phosphodiester Phosphonate Phosphite Phosphonous Phosphinate Phosphine oxide Phosphine Phosphonium
Xanthate
Organosulfur compound of the form >S(=O)2
Silether Silole Silatrane Silicate Phosphorus Phosphate Phosphodiester Phosphonate Phosphite Phosphonous Phosphinate Phosphine oxide Phosphine Phosphonium
Sulfone
Amino acid substitutions that mimic a phosphorylated protein
protein sufficiently to result in significant differences in behavior. Phosphonate-based compounds have been used as phosphotyrosine analogues, as they
Phosphomimetics
Organic compound with the formula P(OR)3
Perkow reaction for the formation of vinyl phosphonates, and in the Michaelis–Arbuzov reaction to form phosphonates. Aryl phosphite esters may not undergo
Phosphite_ester
Functional group with the chemical structure R–S–S–R′
Silether Silole Silatrane Silicate Phosphorus Phosphate Phosphodiester Phosphonate Phosphite Phosphonous Phosphinate Phosphine oxide Phosphine Phosphonium
Disulfide
Cyclic chemical group (–C6H5)
Silether Silole Silatrane Silicate Phosphorus Phosphate Phosphodiester Phosphonate Phosphite Phosphonous Phosphinate Phosphine oxide Phosphine Phosphonium
Phenyl_group
Chemical compound
Agent VP belongs to a class of organophosphates known as 3-pyridyl phosphonates. These agents are extremely potent acetylcholinesterase inhibitors
3,3,5-Trimethylcyclohexyl 3-pyridyl methylphosphonate
3,3,5-Trimethylcyclohexyl_3-pyridyl_methylphosphonate
Species of chestnut tree
further limit the potential range of the American chestnut. Potassium phosphonate has been found to induce resistance to infection of C. sativa by both
American_chestnut
has developed fluorinated phosphonate analogs of biological phosphates, including the first synthesis of the CF2-phosphonate analogs of phosphoserine and
David_B._Berkowitz
Derivatives of nucleosides
present phosphite triester impurity displays peak at 138–140 ppm. H-phosphonate impurities display peaks at 8 and 10 ppm. Nucleoside phosphoramidites
Nucleoside_phosphoramidite
Chemistry rule of thumb
reactive, oligomerization to siloxanes numerous, e.g. phosphine oxides, phosphonates, phosphinates, phosphates numerous, e.g. sulfuric acid, sulfates, sulfoxides
Double_bond_rule
Organic compound
ClFeTPP) forms an ylide. (iii) A rearrangement reaction (in blue) yields a phosphonate. Patel, Ramesh M.; Argade, Narshinha P. (2007). "Facile SN2' Coupling
Ylide
Chemical compound
solution on phosphinic acid solution: HPH2O2 + NH3 → NH4PH2O2 Ammonium phosphonate forms colorless crystals of the orthorhombic system, space group Cmma
Ammonium_phosphinate
Arbuzov, who developed the Michaelis-Arbuzov reaction to deliver alkyl phosphonates from alkyl halides and phosphinites in 1898. Earlier work used nickel
Hirao_coupling
Silether Silole Silatrane Silicate Phosphorus Phosphate Phosphodiester Phosphonate Phosphite Phosphonous Phosphinate Phosphine oxide Phosphine Phosphonium
Reductone
Group of atoms giving a molecule characteristic properties
Silether Silole Silatrane Silicate Phosphorus Phosphate Phosphodiester Phosphonate Phosphite Phosphonous Phosphinate Phosphine oxide Phosphine Phosphonium
Functional_group
Chemical compound
"Esterification of Phosphorus Trichloride with Alcohols; Diisopropyl phosphonate". ChemSpider Synthetic Pages. Royal Society of Chemistry: 488. doi:10
Diisopropyl_phosphite
German chemist (1911–2005)
was a German chemist who published a modified Wittig reaction using phosphonate-stabilized carbanions now called the Horner–Wadsworth–Emmons reaction
Leopold_Horner
Chemical compound
334. Kluge, Arthur F. (1986). "Diethyl [(2-Tetrahydropyranyloxy)methyl]phosphonate". Organic Syntheses. 64: 80. doi:10.15227/orgsyn.064.0080; Collected
Tetrahydropyran
Chemical compound
N-Thiophosphinoyl Ketimines: Preparation of (R)-Diethyl (1-Amino-1-phenylethyl)phosphonate". Organic Syntheses. 94: 313–331. doi:10.15227/orgsyn.094.0313. Roy,
Chlorodiphenylphosphine
Protein found in humans
nucleoside phosphonate adefovir is a MRP2 inhibitor that has been linked to kidney disease. Tenofovir and cidofovir are also nucleoside phosphonates that inhibit
Multidrug resistance-associated protein 2
Multidrug_resistance-associated_protein_2
Process in petroleum processing
SIs with the following functionalities; - Phosphonate ions (-PO3H−) - Phosphate ions (-OPO3H−) - Phosphonate ions (-PO2H−) - Sulphonate ions (-SO3−) -
Oilfield_scale_inhibition
Species of single-celled organism
avocado. Chemical means of control include fumigation and the use of phosphonate fungistats. Fumigation prior to planting may be effective on some life
Phytophthora_cinnamomi
Chemical group, –C(=O)CH3
Silether Silole Silatrane Silicate Phosphorus Phosphate Phosphodiester Phosphonate Phosphite Phosphonous Phosphinate Phosphine oxide Phosphine Phosphonium
Acetyl_group
Chemical group (–CH=CH2)
Silether Silole Silatrane Silicate Phosphorus Phosphate Phosphodiester Phosphonate Phosphite Phosphonous Phosphinate Phosphine oxide Phosphine Phosphonium
Vinyl_group
Chemical group (–N=C=O)
Silether Silole Silatrane Silicate Phosphorus Phosphate Phosphodiester Phosphonate Phosphite Phosphonous Phosphinate Phosphine oxide Phosphine Phosphonium
Isocyanate
Class of chemical compounds
Silether Silole Silatrane Silicate Phosphorus Phosphate Phosphodiester Phosphonate Phosphite Phosphonous Phosphinate Phosphine oxide Phosphine Phosphonium
Selenenic_acid
Phenomenon in reverse osmosis
process and are primarily contains organic compounds such as sulphonate, phosphonate, or carboxylic acid functional groups. The addition of antiscalants hinder
Membrane_scaling
Organic compound containing an –NO2 group
Silether Silole Silatrane Silicate Phosphorus Phosphate Phosphodiester Phosphonate Phosphite Phosphonous Phosphinate Phosphine oxide Phosphine Phosphonium
Nitro_compound
Michaelis–Arbuzov reaction the same reactants are known to form a beta-keto phosphonate which is an important reagent in the Horner–Wadsworth–Emmons reaction
Perkow_reaction
Chemical element with atomic number 62 (Sm)
purpose, samarium-153 is chelated with ethylene diamine tetramethylene phosphonate (EDTMP) and injected intravenously. The chelation prevents accumulation
Samarium
Chemical compound
About-Jaudet, Noël Collignon (1996). "Bis(Trifluoroethyl) (carboethoxymethyl)phosphonate". Organic Syntheses. 73: 152. doi:10.15227/orgsyn.073.0152.{{cite journal}}:
Methylphosphonyl_dichloride
Organic molecule with two different functional groups
Silether Silole Silatrane Silicate Phosphorus Phosphate Phosphodiester Phosphonate Phosphite Phosphonous Phosphinate Phosphine oxide Phosphine Phosphonium
Bifunctionality
Chemical compound and chemical warfare nerve agent
binding to and covalently inactivating the enzyme via transfer of the phosphonate moiety from VX to the active site of AChE; this inactivates AChE and
VX_(nerve_agent)
Chemical group (–CH3) derived from methane
Silether Silole Silatrane Silicate Phosphorus Phosphate Phosphodiester Phosphonate Phosphite Phosphonous Phosphinate Phosphine oxide Phosphine Phosphonium
Methyl_group
PHOSPHONATE
PHOSPHONATE
PHOSPHONATE
PHOSPHONATE
Girl/Female
Muslim
Satellites
Boy/Male
French English Teutonic
Lives in a fortress.
Boy/Male
Hindu, Indian
Well Organised Men
Girl/Female
Tamil
Jasvandi | ஜஸà¯à®µà®‚தீ
Hibiscus flower
Girl/Female
Tamil
Prayerna | பà¯à®°à®¯à¯‡à®°à¯à®¨à®¾
Bhakti, Worship
Girl/Female
Arabic, Indian
Cool; Mountain Covered with Snow
Surname or Lastname
English
English : variant of Zachary.
Boy/Male
Greek
A tyrant of Syracuse.
Boy/Male
Tamil
Mrutyunjay | மரதà¯à®¯à¯à®‚ஜய
One who has won over death. one who is immortal
Male
Finnish
Finnish form of Greek Ioseph, JOOSEPPI means "(God) shall add (another son)."Â
PHOSPHONATE
PHOSPHONATE
PHOSPHONATE
PHOSPHONATE
PHOSPHONATE