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Organic compounds of the form RC(=O)NR′R″
In organic chemistry, an amide, also known as an organic amide or a carboxamide, is a compound with the general formula R−C(=O)−NR′R″, where R, R', and
Amide
Chemical compound
Sodium amide, commonly called sodamide (systematic name sodium azanide), is the inorganic compound with the formula NaNH2. It is a salt composed of the
Sodium_amide
Vitamer of Vitamin B3
consists of a pyridine ring to which a primary amide group is attached in the meta position. It is an amide of nicotinic acid. As an aromatic compound, it
Nicotinamide
Organic compound
formula CO(NH2)2. This amide has two amino groups (−NH2) joined by a carbonyl functional group (−C(=O)−). It is thus the simplest amide of carbamic acid. Urea
Urea
Class of chemical compounds
signalling. The signalling is controlled in part by fatty acid amide hydrolases, which convert the amide to the parent fatty acid. One example of signaling is
Fatty_acid_amide
Macromolecule with repeating units linked by amide bonds
A polyamide is a polymer with repeating units linked by amide bonds. Polyamides occur both naturally and artificially. Examples of naturally occurring
Polyamide
Cleavage of chemical bonds by the addition of water
for the hydrolysis of proteins, fats, oils, and carbohydrates. Ester and amide hydrolysis occurs through nucleophilic acyl substitution where water acts
Hydrolysis
Anion derived from deprotonation of ammonia
referred to as alkali metal amides. Examples include lithium amide, sodium amide, and potassium amide. These salt-like solids are produced by treating liquid
Azanide
Chemical compound
Ergine, also known as lysergic acid amide (LSA or LAA) as well as LA-111, is a psychoactive compound of the ergoline and lysergamide families related
Ergine
Covalent bond between amino acids in a protein chain
In organic chemistry, a peptide bond is an amide type of covalent chemical bond linking two consecutive alpha-amino acids from C1 (carbon number one)
Peptide_bond
Chemical compound
Potassium amide is an inorganic compound with the chemical formula KNH2. Like other alkali metal amides, it is a white solid that hydrolyzes readily.
Potassium_amide
azanides) are a class of coordination compounds composed of a metal center with amide ligands of the form NR2−. Amido complexes of the parent amido ligand NH2−
Metal_amides
Chemical compound
Lithium amide or lithium azanide is an inorganic compound with the chemical formula LiNH2. It is a white solid with a tetragonal crystal structure. Lithium
Lithium_amide
Chemical compound
Erucamide is a fatty acid amide resulting from the formal condensation of erucic acid with ammonia. It has a role as a metabolite in humans and other
Erucamide
Chemical compound
Lithium bis(trimethylsilyl)amide is a lithiated organosilicon compound with the formula LiN(Si(CH3)3)2. It is commonly abbreviated as LiHMDS or Li(HMDS)
Lithium bis(trimethylsilyl)amide
Lithium_bis(trimethylsilyl)amide
In chemistry, the term amide (/ˈæmaɪd/ or /ˈæmɪd/ or /ˈeɪmaɪd/) is a compound with the functional group RnE(=O)xNR2, where x is not zero, E is some element
Amide_(functional_group)
Dopaminergic agent
DopAmide, or L-DopAmide, is a synthetic levodopa (L-DOPA) analogue that can serve as a levodopa and dopamine prodrug and is of potential interest in the
DopAmide
Chemical compound
hydroxyethylamide (LSH or LAH), also known as lysergic acid N-(α-hydroxyethyl)amide or as lysergic acid methyl carbinolamide, is a lysergamide alkaloid related
Lysergic acid hydroxyethylamide
Lysergic_acid_hydroxyethylamide
Pharmaceutical compound
Isoergine, also known as isolysergic acid amide (iso-LSA or iso-LA-819), isolysergamide, or erginine, is a serotonergic psychedelic of the ergoline and
Isoergine
Organic reaction where amide is converted to Amine or Aldehyde
Amide reduction is a reaction in organic synthesis where an amide is reduced to either an amine or an aldehyde functional group. Catalytic hydrogenation
Amide_reduction
Chemical compound
act as a nucleophile under certain conditions. Lithium amide Lithium bis(trimethylsilyl)amide (LiHMDS) Lithium tetramethylpiperidide (LiTMP) Evans pKa
Lithium_diisopropylamide
Type of chemical reaction
rearrangement (Hofmann degradation) is the organic reaction of a primary amide to a primary amine with one less carbon atom. The reaction involves oxidation
Hofmann_rearrangement
Chemical compound
N-Acetylcysteine amide (abbrev. NACA, AD4 and also known as acetylcysteinamide) is an amide derivative of N-acetylcysteine (NAC) that appears to have better
Acetylcysteinamide
Thermoplastic elastomer
Polyether block amide or PEBA is a thermoplastic elastomer (TPE). It is known under the tradename of PEBAX® (Arkema) and VESTAMID® E (Evonik Industries)
Polyether_block_amide
Chemical reaction
the synthesis of aldehydes by reduction of the amide with an excess of lithium aluminum hydride (see amide reduction). The major advantage of this method
Weinreb_ketone_synthesis
Chemical compound
the amide derived from the fatty acid oleic acid. It is a colorless waxy solid and occurs in nature. Sometimes labeled as a fatty acid primary amide (FAPA)
Oleamide
Topics referred to by the same term
A transition metal amide complex may refer to: A transition metal carboxamide complex A transition metal inorganic amide This disambiguation page lists
Transition metal amide complex
Transition_metal_amide_complex
Chemical compound
commonly used for activation of carboxylic acids, particularly for amide synthesis. Amide coupling is one of the most common reactions in organic chemistry
DMTMM
Common name for flowering plants in the family Convolvulaceae
and/or psychedelic lysergamides ergine (lysergic acid amide; LSA) and isoergine (isolysergic acid amide; iso-LSA), which are closely structurally related
Morning_glory
Small motifs in proteins and polypeptides
Amide rings are small motifs in proteins and polypeptides. They consist of 9-atom or 11-atom rings formed by two CO...HN hydrogen bonds between a side
Amide_ring
Chemical compound
to activate carboxylic acids for reaction with amines in the context of amide bond formation and peptide synthesis. TCFH is commercially available. It
TCFH
Organic chemical compound
Acrylamide (or acrylic amide) is an organic compound with the chemical formula CH2=CHC(O)NH2. It is a white odorless solid, soluble in water and several
Acrylamide
Glutathione amide reductase (EC 1.8.1.16, GAR) is an enzyme with systematic name glutathione amide:NAD+ oxidoreductase. This enzyme catalyses the following
Glutathione_amide_reductase
Cyclic amide
cyclic amide, formally derived from an amino carboxylic acid through cyclization reactions. The term is a portmanteau of the words lactone + amide. Greek
Lactam
Chemical compound
deprotonation of bis(trimethylsilyl)amine. For example, lithium bis(trimethylsilyl)amide (LiHMDS) is prepared using n-butyllithium: [(CH3)3Si]2NH + BuLi → [(CH3)3Si]2NLi
Bis(trimethylsilyl)amine
Chemical compound
8-dithiooctanoic amide. It is the functional form of lipoic acid, i.e the carboxyl group is attached to protein via an amine with an amide linkage. Illustrative
Lipoamide
Chemical compound
a carboxyl activating agent for the coupling of primary amines to yield amide bonds. While other carbodiimides like dicyclohexylcarbodiimide (DCC) or
1-Ethyl-3-(3-dimethylaminopropyl)carbodiimide
1-Ethyl-3-(3-dimethylaminopropyl)carbodiimide
Group of chemicals
complexes composed of a cationic metal M with anionic bis(trimethylsilyl)amide ligands (the −N(Si(CH3)3)2 monovalent anion, or −N(Si(CH3)3)2 monovalent
Metal bis(trimethylsilyl)amides
Metal_bis(trimethylsilyl)amides
Mammalian protein found in humans
Fatty-acid amide hydrolase 1 (FAAH) is a member of the serine hydrolase family of enzymes. It was first shown to break down anandamide (AEA), an N-acylethanolamine
Fatty-acid_amide_hydrolase_1
Method for producing 2-aminopyridine derivatives
producing 2-aminopyridine derivatives by the reaction of pyridine with sodium amide. It was reported by Aleksei Chichibabin in 1914. The following is the overall
Chichibabin_reaction
Pharmaceutical compound
LA-3Cl-SB, also known as Cl-LSB or as lysergic acid N-(3-chloro-sec-butyl)amide, is a putative serotonergic psychedelic of the lysergamide family related
LA-3Cl-SB
Chemical compound
CH3CH2C=O(NH2). It is the amide of propanoic acid. This organic compound is a mono-substituted amide. Organic compounds of the amide group can react in many
Propanamide
Chemical compound
ethanamide) is an organic compound with the formula CH3CONH2. It is an amide derived from ammonia and acetic acid. It finds some use as a plasticizer
Acetamide
Class of chemical compounds
The simplest lysergamides are ergine (lysergic acid amide; LSA) and isoergine (iso-lysergic acid amide; iso-LSA). In terms of pharmacology, the lysergamides
Lysergamides
Chemical compound
Isovaleramide is an organic compound with the formula (CH3)2CHCH2C(O)NH2. The amide derived from isovaleric acid, it is a colourless solid. Isovaleramide is
Isovaleramide
Class of chemical compounds
of local anesthetics. They are named for their ester bond and are unlike amide local anaesthetics. Structurally, amino esters consist of three molecular
Amino_esters
Chemical reaction
The von Braun amide degradation is the chemical reaction of a monosubstituted amide with phosphorus pentachloride or thionyl chloride to give a nitrile
Von_Braun_amide_degradation
Class of chemical compounds
Chloramines refer to derivatives of ammonia and organic amines wherein one or more N−H bonds have been replaced by N−Cl bonds. Two classes of compounds
Chloramines
Chemical compound
Potassium bis(trimethylsilyl)amide (commonly abbreviated as KHMDS, Potassium(K) HexaMethylDiSilazide) or potassium hexamethyldisilazane is the chemical
Potassium bis(trimethylsilyl)amide
Potassium_bis(trimethylsilyl)amide
Class of enzymes
L-proline amide hydrolase (EC 3.5.1.101, S-stereoselective piperazine-2-tert-butylcarboxamide hydrolase, LaaA, L-amino acid amidase) is an enzyme with
L-proline_amide_hydrolase
Chemical compound
(INNTooltip International Nonproprietary Name), is an endogenous fatty acid amide, and lipid modulator. PEA is not a classic endocannabinoid because it lacks
Palmitoylethanolamide
Chemical compound
organic compound with the chemical formula of C7H7NO. It is the simplest amide derivative of benzoic acid. In powdered form, it appears as a white solid
Benzamide
Organic compound (CH3COCl)
Acetyl chloride (CH3COCl) is an acyl chloride derived from acetic acid (CH3COOH). It belongs to the class of organic compounds called acid halides. It
Acetyl_chloride
Class of enzymes that can form bonds between molecules
In biochemistry, a ligase is an enzyme that can catalyze the joining (ligation) of two molecules by forming a new chemical bond. This is typically via
Ligase
Glutathione amide-dependent peroxidase (EC 1.11.1.17) is an enzyme with systematic name glutathione amide:hydrogen-peroxide oxidoreductase. This enzyme
Glutathione amide-dependent peroxidase
Glutathione_amide-dependent_peroxidase
Reaction that converts amino acids into a keto-amides
reaction is a chemical reaction that transforms an amino-acid into a keto-amide using an acid anhydride and a base, typically pyridine. It is named for
Dakin–West_reaction
Transamidation is a chemical reaction in which an amide reacts with an amine to generate a new amide: RC(O)NR'2 + HNR"2 → RC(O)NR"2 + HNR'2 The reaction
Transamidation
Digestive enzyme
Chymotrypsin preferentially cleaves peptide amide bonds where the side chain of the amino acid N-terminal to the scissile amide bond (the P1 position) is a large
Chymotrypsin
Enzyme found in humans
Biotinidase (EC 3.5.1.12, amidohydrolase biotinidase, BTD), also known as biotinase, is an enzyme that in humans is encoded by the BTD gene. The enzyme
Biotinidase
can exists in two tautomeric forms: hydrazide imides (RC(=NH)NHNH2) and amide hydrazones (RC(NH2)=NNH2). Some amidrazones have been employed as insecticides
Amidrazone
Class of synthetic fiber related to nylon
lightweight consumer items, such as phone cases and tennis rackets. Individual amide molecules forming the aramid chain polymerise in the direction of the fiber
Aramid
unstable because its amide group has the amine lone pair and the carbonyl group not properly aligned, as may be expected for an amide, as a result of steric
Quinuclidone
Family of neuropeptides
Vaudry H, Seong JY (2014). "Does Kisspeptin Belong to the Proposed RF-Amide Peptide Family?". Front Endocrinol (Lausanne). 5: 134. doi:10.3389/fendo
RFamide_peptide_family
Spicy food additive
vanillylamide or PAVA, is an organic compound and a capsaicinoid. It is an amide of pelargonic acid (n-nonanoic acid) and vanillyl amine. It is present in
Nonivamide
Protein family
enzyme that catalyzes the hydrolysis of an amide. In this way, the two substrates of this enzyme are an amide and H2O, whereas its two products are a carboxylate
Amidase
Chemical compound
University. It is a structural isomer of LSD, with the two ethyl groups on the amide nitrogen having been replaced by a single sec-butyl group, joined at the
Lysergic_acid_2-butylamide
Quasiparticle used to model vibrations within proteins
quasiparticle representing an excitation propagating along the self-trapped amide I groups within the α-helices of proteins. It is a solution of the Davydov
Davydov_soliton
Chemical compound (fatty acid neurotransmitter)
from the Sanskrit word ananda (आनन्द), meaning "joy, bliss, delight," plus amide. Anandamide, the first discovered endocannabinoid, engages with the body's
Anandamide
Class of chemical compounds
Ethanolamides are chemical compounds which are amides formed from carboxylic acids and ethanolamine. Some ethanolamides are naturally occurring, such as
Ethanolamide
Chemical compound
Sodium bis(trimethylsilyl)amide is the organosilicon compound with the formula NaN(Si(CH3)3)2. This species, usually called NaHMDS (sodium hexamethyldisilylamide)
Sodium bis(trimethylsilyl)amide
Sodium_bis(trimethylsilyl)amide
Chemical compound
2-Methylacrylamide; 2-Methylpropenamide; α-Methyl acrylic amide; Methacrylic acid amide; Methacrylic amide; Methylacrylamide Identifiers CAS Number 79-39-0 Y
Methacrylamide
Chemical compound
and hydrogen bonding due to its cis-amide conformation. NMP is produced industrially by a typical ester-to-amide conversion, by treating gamma-butyrolactone
N-Methyl-2-pyrrolidone
This list contains a list of EC numbers for the sixth group, EC 6, ligases, placed in numerical order as determined by the Nomenclature Committee of the
List_of_EC_numbers_(EC_6)
The α-Ketoacid-Hydroxylamine (KAHA) Amide-Forming Ligation is a chemical reaction that is used to join two unprotected fragments in peptide synthesis
KAHA_Ligation
Chemical compound
N-Nitrosodimethylamine Names Preferred IUPAC name N,N-Dimethylnitrous amide Identifiers CAS Number 62-75-9 Y 3D model (JSmol) Interactive image ChEBI
N-Nitrosodimethylamine
Early synthetic polymer developed as a textile fiber
Nylon is a family of synthetic polymers characterized by amide linkages, typically connecting aliphatic or semi-aromatic groups. Nylons are generally
Nylon
Chemical compound
proposed. The main difficulty arises from the ambiguous use of the word amide to mean an acylated (including sulfonylated) amine or the anionic form of
Bistriflimide
Chemical compound
with Hünig's base (N,N-diisopropylethylamine), or triethylamine to form amide bonds. Typically dimethylformamide is used as solvent, although other polar
HATU
Chemical reaction
amidation) is a chemical reaction that transforms a nitrile into an N-alkyl amide using various electrophilic alkylating reagents. The original reaction formed
Ritter_reaction
Pharmaceutical compound
definite known psychoactive effects in humans is the lysergamide lysergic acid amide (LSA; ergine). DCLA showed effects in preclinical research suggestive of
Descarboxylysergic_acid
carboxamide complexes are coordination complexes containing one or more amide ligands (RC(O)NH2 being the simplest members) bound to a transition metal
Transition metal carboxamide complex
Transition_metal_carboxamide_complex
Chemical compound
N,N′-Dicyclohexylcarbodiimide (DCC or DCCD) is an organic compound with the chemical formula (C6H11N)2C. It is a waxy white solid with a sweet odor. Its
N,N'-Dicyclohexylcarbodiimide
Patient with little to no pain or negative affect
negative affect. She has two mutations, one in the gene encoding fatty acid amide hydrolase (FAAH) and one in the pseudogene FAAH-OUT modulating FAAH expression
Jo_Cameron
Chemical compound
Angiotensinamide (INN; BAN and USAN angiotensin amide) is a potent vasoconstrictor used as a cardiac stimulant. It is a derivative of angiotensin II.
Angiotensinamide
Chemical compound
Dansyl amide is a fluorescent dye that forms in a reaction between dansyl chloride and ammonia. It is the simplest representative of the class of dansyl
Dansyl_amide
Chemical compound
it a useful organic reagent. It is commonly used as the hindered base in amide coupling reactions between a carboxylic acid (typically activated, for example
N,N-Diisopropylethylamine
Species of plant
ergoline alkaloids such as ergine (lysergic acid amide; LSA) and isoergine (isolysergic acid amide; iso-LSA). A study reported stereoisomers of ergine
Argyreia_nervosa
Chemical group (R–C=O)
amide bond between the carbonyl carbon and the amide nitrogen has significant double bond character. The energy barrier for rotation about an amide bond
Acyl_group
Medication to treat cardiac arrhythmias
carboxylic acid derivatives consisting of an amide with a benzamide moiety and a triethylamine attached to the amide nitrogen. In certain lines, the para-amino
Procainamide
Pharmaceutical compound
diethylamide (LSD). It is the N-methyl derivative of ergine (lysergic acid amide; LSA) and the analogue of LSD in which the N,N-diethyl groups have been
Lysergic_acid_methylamide
Pharmaceutical compound
lysergic acid diethylamide (LSD). It is the analogue of LSD in which the amide group has two propyl substitutions instead of two ethyl substituents. The
Lysergic_acid_dipropylamide
Chemical compound
potency as a dopamine reuptake inhibitor to cocaine. It is synthesized by an amide condensation reaction between benzoylecgonine and dimethylamine.
RTI-160
New alkyl group
benzyl quaternary ammonium salts. The reagent is sodium amide or another alkali metal amide and the reaction product a N,N-dialkylbenzylamine with a
Sommelet–Hauser_rearrangement
Chemical compound
phytoestrogen. It has also been found to be a weak inhibitor of fatty acid amide hydrolase in vitro. The enzyme biochanin-A reductase converts biochanin
Biochanin_A
Species of flowering plant
(2E,6Z,8E)-deca-2,6,8-trienoic acid isobutyl amide (2E,7Z,9E)-Undeca-2,7,9-trienoic acid isobutyl amide, another alkylamide from Acmella oleracea (2E)-Undeca-2-en-8
Acmella_oleracea
Procedures for isolating and purifying products of a chemical reaction
between a secondary amine (1) and an acyl chloride (2) yields the desired amide (4) as shown below. The acyl chloride is added slowly to a solution of the
Work-up
Chemical compound
Hexamethylphosphoramide, often abbreviated HMPA, is a phosphoramide (an amide of phosphoric acid) with the formula [(CH3)2N]3PO. This colorless liquid
Hexamethylphosphoramide
Enzyme found in humans
completely inactivated at a pH of 8. Selective inhibitors of NAAA are ester and amide compounds, such as N-cyclohexanecarbonylpentadecylamine. NAAA is cleaved
N-acylethanolamine acid amidase
N-acylethanolamine_acid_amidase
Family of chemical compounds
β-lactam (beta-lactam) ring is a four-membered lactam. A lactam is a cyclic amide, and beta-lactams are named so because the nitrogen atom is attached to
Β-Lactam
Chemical compound
Isonicotinamide (pyridine-4-carboxamide) is the amide form of isonicotinic acid. It is an isomer of nicotinamide, which has the carboxamide group in the
Isonicotinamide
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