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Class of medications used primarily to treat high blood pressure
lowering blood pressure. As a result of inhibiting the ACE enzyme in the bradykinin system, the ACE inhibitor drugs allow for increased levels of bradykinin
ACE_inhibitor
ACE inhibitor medication
Enalapril, sold under the brand name Vasotec among others, is an ACE inhibitor medication used to treat high blood pressure, diabetic kidney disease,
Enalapril
Disease characterized by rapid swelling
inherited problem known as C1 esterase inhibitor deficiency, medications known as angiotensin-converting enzyme inhibitors, or a lymphoproliferative disorder
Angioedema
Drug discovery
converting enzyme (ACE) inhibitors in regulating blood pressure. This led to the development of captopril, the first ACE inhibitor. When the adverse effects
Discovery and development of ACE inhibitors
Discovery_and_development_of_ACE_inhibitors
Medication used to treat hypertension and heart failure
other ACE inhibitors, it is not a prodrug, is not metabolized by the liver, and is excreted unchanged in the urine. Lisinopril is an ACE inhibitor, meaning
Lisinopril
Combination of antihypertensive drugs
An ACE inhibitor and thiazide combination is a drug combination used to treat hypertension (high blood pressure). They are given by mouth. ACE inhibitors
ACE inhibitor and thiazide combination
ACE_inhibitor_and_thiazide_combination
Combination medication
receptor-neprilysin inhibitor" (ARNi). In 2016, the American College of Cardiology/American Heart Association Task Force recommended it as a replacement for an ACE inhibitor
Sacubitril/valsartan
Antihypertensive drug of the ACE inhibitor class
enzyme (ACE) inhibitor used for the treatment of hypertension and some types of congestive heart failure. Captopril was the first oral ACE inhibitor found
Captopril
ACE inhibitor medication
Ramipril, sold under the brand name Altace among others, is an ACE inhibitor type medication taken by mouth used to treat high blood pressure, heart failure
Ramipril
Group of pharmaceuticals that modulate the renin–angiotensin system
patients taking ACE inhibitors to patients taking ARBs, fewer ARB patients withdrew from the study due to adverse events compared to ACE inhibitor patients.
Angiotensin II receptor blocker
Angiotensin_II_receptor_blocker
Chemical compound
angiotensin-converting enzyme (ACE) inhibitor drugs. It is thought that bradykinin is converted to inactive metabolites by ACE, therefore inhibition of this
Bradykinin
Compound inhibiting the activity of renin
II that facilitates blood pressure. Renin inhibitor is often preceded by direct, called direct renin inhibitor in order to distinguish its mechanism from
Renin_inhibitor
Combination medication
Noliprel) is a combination medication which contains perindopril (an ACE inhibitor) and indapamide (a thiazide-like diuretic) both of which are used for
Perindopril/indapamide
When dysfunction of the kidneys or heart induces dysfunction in the other
drug. The use of ACE inhibitors have long term protective effect on kidney and heart tissue. Angiotensin inhibition with an ACE inhibitor or angiotensin
Cardiorenal_syndrome
Mammalian protein found in humans
angiotensin II. Therefore, ACE indirectly increases blood pressure by causing blood vessels to constrict. ACE inhibitors are widely used as pharmaceutical
Angiotensin-converting_enzyme
Angiotensin II receptor antagonist
antagonist. This mechanism of action is different than that of the ACE inhibitor drugs, which block the conversion of angiotensin I to angiotensin II
Valsartan
Antihypertensive drug of the ACE inhibitor class
enzyme (ACE) inhibitor used for the treatment of hypertension and some types of chronic heart failure. Fosinopril is the only phosphonate-containing ACE inhibitor
Fosinopril
Condition involving an enlarged, ineffective heart
those with heart failure, treatment may include medications in the ACE inhibitor, beta blocker, and diuretic families. A low salt diet may also be helpful
Dilated_cardiomyopathy
Enlargement of the heart
(ARBs): to provide the benefits of ACE inhibitors for patients with ACE inhibitor issues. Beta blockers: to lower blood pressure and improve heart function
Cardiomegaly
Hormone system
of the more potent angiotensin II. Captopril is an example of an ACE inhibitor. ACE cleaves a number of other peptides, and in this capacity is an important
Renin–angiotensin_system
Breakdown product of creatine phosphate
concentrations may increase when an ACE inhibitor (ACEI) is taken for heart failure and chronic kidney disease. ACE inhibitors provide survival benefits for
Creatinine
Blood pressure medication
first-line treatment in people under the age of 55 who cannot tolerate an ACE inhibitor. One study demonstrated losartan was superior to atenolol in the primary
Losartan
Dog breed
hereditary nephritis in samoyed dogs with angiotensin converting enzyme (ACE) inhibitor". Journal of Comparative Pathology. 117 (3): 209–225. doi:10
Samoyed_dog
Topics referred to by the same term
Look up ace, aces, or ACE in Wiktionary, the free dictionary. An ace is a playing card. Ace, Aces, ACE or ACES may also refer to: ACE (video game), a
Ace_(disambiguation)
Informal classification of pharmaceutical drugs
drugs Pepcid and Axid. Several me-toos followed the prototype of the ace inhibitor, captopril, with enalapril being its first me-too. Most were as efficient
Me-too_drug
Excessive enlargement of the human aorta
placebo controlled RCT conducted later found no significant effect of the ACE inhibitor perindopril or the calcium channel blocker amlodipine after 2 years
Aortic_aneurysm
Combination drug used to treat high blood pressure
treatment of high blood pressure (hypertension). It contains lisinopril, an ACE inhibitor, and hydrochlorothiazide, a diuretic. Typically, it becomes an option
Lisinopril/hydrochlorothiazide
Lisinopril/hydrochlorothiazide
Combination drug used to treat high blood pressure
to treat high blood pressure. It is a combination of lisinopril, an ACE inhibitor, with amlodipine, a calcium channel blocker. It may be used when blood
Lisinopril/amlodipine
Pharmaceutical drug classification
ATC code C09 Agents acting on the renin–angiotensin system is a therapeutic subgroup of the Anatomical Therapeutic Chemical Classification System, a system
ATC_code_C09
Chemical compound
progression of heart disease. An ACE inhibitor, often enalapril (brand name Enacard) or benazepril (Fortekor). These drugs inhibit the action of angiotensin-converting
Pimobendan
American biochemist (1930–2004)
Argentine-born American chemist who first synthesized captopril, the first ACE inhibitor that was used to treat heart disease. With his co-worker, David Cushman
Miguel_Ondetti
Chemical compound
Bothrops jararaca. It is an angiotensin converting enzyme inhibitor (ACE inhibitor) which inhibits the conversion of angiotensin I to angiotensin II and may
Teprotide
Antihypertensive drug of the ACE inhibitor class
Moexipril was an angiotensin converting enzyme inhibitor (ACE inhibitor) used for the treatment of hypertension and congestive heart failure. Moexipril
Moexipril
Pharmaceutical drug
adults with C1-esterase-inhibitor deficiency. It is not effective in angioedema caused by medication from the ACE inhibitor class. It is a peptidomimetic
Icatibant
Thickening, hardening and loss of elasticity of the walls of arteries
g., statins, cholesterol absorption inhibitors), medications to treat high blood pressure (e.g., ACE inhibitors, angiotensin II receptor blockers), and
Arteriosclerosis
Class of drugs to lower cholesterol
dihydroxybergamottin) inhibit the cytochrome P450 enzyme CYP3A4, which is involved in the metabolism of most statins (however, it is a major inhibitor of only lovastatin
Statin
Class of drugs used to treat high blood pressure
blockers, ACEis, or ARBs. There are fixed-dose combination drugs, such as ACE inhibitor and thiazide combinations. Despite thiazides being cheap and effective
Antihypertensive
Medication class with multiple uses
sustained-release metoprolol are specifically indicated as adjuncts to standard ACE inhibitor and diuretic therapy in congestive heart failure, although at doses
Beta_blocker
Interruption of cardiac blood supply
medication causes a temporary decrease in the heart's ability to pump blood. ACE inhibitor therapy should be started within 24 hours and continued indefinitely
Myocardial_infarction
Genetic disorder involving connective tissue
blockers such as propranolol or atenolol, calcium channel blockers, ACE inhibitors, and/or angiotensin receptor blockers (ARBs). Surgery may be required
Marfan_syndrome
Medication against high blood pressure
failed individually, or amlodipine alone caused edema. Benazepril is an ACE inhibitor and blocks the conversion of angiotensin I to angiotensin II in the
Amlodipine
Medical condition
angiotensin-converting enzyme (ACE) inhibitor-induced angioedema, hereditary angioedema, as well as angioedema due to acquired C1 inhibitor deficiency, must be taken
Chronic_spontaneous_urticaria
Class of therapeutic drug
is especially a risk if the patient is also concomitantly taking an ACE inhibitor (which removes angiotensin II's vasoconstriction of the efferent arteriole)
Nonsteroidal anti-inflammatory drug
Nonsteroidal_anti-inflammatory_drug
Medical condition
administering morphine, diuretics like furosemide, addition of an ACE inhibitor, use of nitrates and use of digoxin if indicated for the heart failure
Acute decompensated heart failure
Acute_decompensated_heart_failure
Thiazide-like diuretic drug
decompensated heart failure. Combination preparations with perindopril (an ACE inhibitor antihypertensive) are available. The thiazide-like diuretics (indapamide
Indapamide
High blood pressure medication
or stable coronary artery disease. As a long-acting ACE inhibitor, perindopril works by inhibiting production of the vasoconstriction hormone, angiotensin
Perindopril
bedinvetmab - nerve growth factor inhibitor monoclonal antibody used for osteoarthritis in dogs benazepril – ACE-inhibitor used in heart failure, hypertension
List_of_veterinary_drugs
Index of chemical compounds with the same molecular formula
Ceronapril, a phosphonate ACE inhibitor that was never marketed Fosinopril, an angiotensin converting enzyme (ACE) inhibitor This set index page lists
C30H46NO7P
Combination drug
channel blocker, and an immediate release formulation of trandolapril, an ACE inhibitor. The patent, held by Abbott Laboratories, expired on February 24, 2015
Trandolapril/verapamil
Sudden expulsion of air from the lungs as a reflex to clear irritants
inhibitors (ACE inhibitors) and beta blockers. Treatment should target the cause; for example, smoking cessation or discontinuing ACE inhibitors. Cough
Cough
Anabolic steroid
bradykinin peptide is well known to promote a cough reaction associated with ACE inhibitor medications prescribed for hypertension. Trenbolone has both anabolic
Trenbolone
Medical condition
of angiotensin-converting enzyme (ACE) inhibitors, angiotensin II antagonists (ARBs), and some neprilysin inhibitors. The angioedema appears to be dose
Drug-induced_angioedema
terazosin tolazoline urapidil Class of antihypertensives that bind to and inhibit the angiotensin II receptor type 1 and thereby block the arteriolar contraction
List of cardiac pharmaceutical agents
List_of_cardiac_pharmaceutical_agents
Group of similar medications
cyclooxygenase inhibitor Proton-pump inhibitor Renin inhibitor Selective glucocorticoid receptor modulator Serotonergic Statin – HMG-CoA reductase inhibitor This
Drug_class
Angiotensin II receptor antagonist
antagonists, eprosartan is generally better tolerated than enalapril (an ACE inhibitor), especially among the elderly. The compound came into the Abbott Laboratories
Eprosartan
Medication
taking an ACE inhibitor or ARB. Such patients should consider alternative antihypertensive treatment as necessary. Aliskiren is an inhibitor of renin.
Aliskiren
Accumulation of collagen in the skin and internal organs
uniformly fatal. While outcomes have improved significantly with the use of ACE inhibitors, the prognosis is often guarded, as a significant number of patients
Systemic_scleroderma
Hormone system
[citation needed] C1-inhibitor is a serine protease inhibitor (serpin) protein. C1-INH is the most important physiological inhibitor of plasma kallikrein
Kinin–kallikrein_system
Group of peptide hormones in mammals
pharmacological environment. ACE inhibitor Angiotensin receptor Angiotensin II receptor antagonist Captopril Perindopril Renin inhibitor GRCh38: Ensembl release
Angiotensin
Antihypertensive drug of the ACE inhibitor class
Imidapril, sold under the brand name Tanatril among others, is an ACE inhibitor used as an antihypertensive drug and for the treatment of chronic heart
Imidapril
Formulary by the World Health Organization
> 60 years Alternatives are 4th level ATC chemical subgroup (C09AA ACE inhibitors, plain) Hydralazine is listed for use only in the acute management of
WHO Model List of Essential Medicines
WHO_Model_List_of_Essential_Medicines
Medical condition
per se is as yet unclear.[citation needed] Currently treatment with ACE inhibitors, calcium channel blockers, beta blockers, and angiotensin receptor blockers
Heart failure with preserved ejection fraction
Heart_failure_with_preserved_ejection_fraction
Medical condition
antagonists". PMID 30394825. {{cite web}}: Missing or empty |url= (help) "ACE inhibitor fetopathy and hypocalvaria: the kidney-skull connection". PMID 1771591
Acalvaria
Vasodilating drug
A phosphodiesterase type 5 inhibitor (PDE5 inhibitor) is a vasodilating drug that works by blocking the degradative action of cGMP-specific phosphodiesterase
PDE5_inhibitor
Inflammation of the heart muscle
Treatment depends on both the severity and the cause. Medications such as ACE inhibitors, beta blockers, and diuretics are often used. A period of no exercise
Myocarditis
Medication used to treat high blood pressure and heart failure
may harm the baby, while use when breastfeeding may be safe. It is an ACE inhibitor and works by decreasing renin-angiotensin-aldosterone system activity
Benazepril
NSAID analgesic and anti-inflammatory drug
of nabumetone on blood pressure control in hypertensive patients on ACE inhibitors are also good,[clarification needed] equivalent to paracetamol. In 2023
Nabumetone
Minor form of stroke
mainly obtained through the ingestion of angiotensin-converting enzyme (ACE) inhibitor or a diuretic. There is inconsistent evidence regarding the effect of
Transient_ischemic_attack
Chemical compound
among others, is an ACE inhibitor antihypertensive drug used to treat hypertension. It belongs to dicarboxy group of ACE inhibitors.[citation needed] It
Spirapril
Use of five or more medications daily
first year after a myocardial infarction may include: a statin, an ACE inhibitor, a beta-blocker, aspirin, paracetamol and an antidepressant. In anesthesia
Polypharmacy
Topics referred to by the same term
Acei or variation, may refer to: ACE inhibitor (ACEI) Angiotensin-converting-enzyme inhibitors Pseudotropheus sp. "acei" (fish), the acei, a cichlid Association
Acei
Abnormal formation of clumps of inflammatory cells (granulomata)
Sarcoidosis" at ClinicalTrials.gov Kaura V, Kaura SH, Kaura CS (2007). "ACE Inhibitor in the treatment of cutaneous and lymphatic sarcoidosis". American Journal
Sarcoidosis
Species of snake
currently recognized. The drugs known as angiotensin converting enzyme (ACE) inhibitors, used for the treatment of hypertension and some types of congestive
Bothrops_jararaca
Antihypertensive drug of the ACE inhibitor class
reduce high blood pressure. It is an angiotensin-converting enzyme (ACE) inhibitor. In small studies, zofenopril appeared significantly more effective
Zofenopril
Group of antihypertensive drugs
saralasin, the first Ang II antagonist, and the development of the first ACE inhibitor captopril, it was generally acknowledged that Ang II receptor antagonists
Discovery and development of angiotensin receptor blockers
Discovery_and_development_of_angiotensin_receptor_blockers
Diuretics that act along the loop of Henle in the kidneys
precipitate kidney failure in patients concurrently taking an NSAID and an ACE inhibitor—the so-called "triple whammy" effect. Because furosemide, torsemide
Loop_diuretic
Antihypertensive drug of the ACE inhibitor class
Cilazapril is an angiotensin-converting enzyme inhibitor (ACE inhibitor) used for the treatment of hypertension and congestive heart failure. It was patented
Cilazapril
Class of drugs for reducing stomach acid
the most widely sold medications in the world. The class of proton-pump inhibitor medications is on the World Health Organization's List of Essential Medicines
Proton-pump_inhibitor
Mushroom
anticancer agent. Shimeji mushrooms contain angiotensin I-converting enzyme (ACE) inhibitor which is an oligopeptide that may be helpful in lowering blood pressure
Shimeji
Species of bacterium
pressure due to the presence of manufactured tripeptides that have ACE inhibitor activity. However, results have been contradictory in later studies
Lactobacillus_helveticus
Changes in the physiology of the heart
infarction and chronic pressure overload. Clinical trials have shown that ACE inhibitor therapy after myocardial infarction leads to improved myocardial performance
Ventricular_remodeling
Diabetes medication
treatment period of 2.4 years of participants who had already been under ACE inhibitor or angiotensin II receptor blocker therapy that the events of a sustained
Dapagliflozin
Type of drug
Omapatrilat - also inhibits ACE Phosphoramidon - inhibitor of neprilysin and thermolysin; also inhibits ECE RB-101 - also inhibits aminopeptidase N (APN)
Endopeptidase_inhibitor
Active metabolite of the drug enalapril
active metabolite of enalapril. It is the first dicarboxylate-containing ACE inhibitor and was developed partly to overcome these limitations of captopril
Enalaprilat
Antihypertensive drug of the ACE inhibitor class
Trandolapril is an ACE inhibitor used to treat high blood pressure. It may also be used to treat other conditions. It is similar in structure to another
Trandolapril
Chemical compound
Temocapril (also known as temocaprilum [Latin]; brand name Acecol) is an ACE inhibitor. It was not approved for use in the US. It is administered as inactive
Temocapril
Chemical compound
Rentiapril is an ACE inhibitor. Takase K, Ikuse T, Aono H, Okahara A (January 1995). "Toxicity study of the angiotensin converting enzyme inhibitor rentiapril
Rentiapril
Exopeptidase enzyme that acts on angiotensin I and II
important role of ACE inhibitors, but not ARBs, in reducing the risk of pneumonia. These data may discourage the withdrawal of ACE inhibitors in some patients
Angiotensin-converting enzyme 2
Angiotensin-converting_enzyme_2
Drug study for hypertension patients
(diuretic) versus doxazosin (alpha-adrenergic blocker), lisinopril (ACE-inhibitor), and amlodipine (calcium channel blocker). The doxazosin arm was discontinued
Antihypertensive and Lipid Lowering Treatment to Prevent Heart Attack Trial
Antihypertensive_and_Lipid_Lowering_Treatment_to_Prevent_Heart_Attack_Trial
Interspecies relationship
Karen; Shykoff, Barbara; Izzo, Joseph (2001). "Pet ownership, but not ace inhibitor therapy, blunts home blood pressure responses to mental stress". Hypertension
Human–canine_bond
Low blood pressure after blood products given
(ACE) is primarily responsible for its degradation (75%) but can be inhibited by administration of blood pressure medications called ACE inhibitors. Polymorphisms
Hypotensive transfusion reaction
Hypotensive_transfusion_reaction
Diuretic medication
with pimobendan, spironolactone, and an angiotensin-converting enzyme (ACE) inhibitor for the management of pulmonary edema (fluid build-up in lungs) in dogs
Torasemide
Sudden decrease in kidney function that develops within seven days
cardiogenic shock, heart failure, cirrhosis, and certain medications such as ACE inhibitors or NSAIDs. Intrinsic renal causes of AKI include glomerulonephritis
Acute_kidney_injury
Antihypertensive drug of the ACE inhibitor class
Alacepril (INN) is an ACE inhibitor medication indicated as a treatment for hypertension. The medication metabolizes to captopril and desacetylalacepril
Alacepril
Aspartic protease protein and enzyme
losartan, irbesartan or candesartan) rather than a direct oral renin inhibitor. ACE inhibitors or ARBs are also part of the standard treatment after a heart
Renin
ACE inhibitor used in the treatment of hypertension and congestive heart failure
with a history of angioedema related to previous treatment with an ACE inhibitor Hypersensitivity to Quinapril Side effects of Quinapril include dizziness
Quinapril
Antihypertensive medication
essential hypertension. It may have a role when thiazides, beta-blockers, ACE inhibitors, and calcium channel blockers are not appropriate or have failed to
Moxonidine
Health of dogs
survival outcomes than those receiving benazepril (an ACE inhibitor) plus furosemide. However, ACE inhibitors and pimobendan have different mechanisms of action
Dog_health
ACE inhibitor (ACEi) therapy is recommended for all patients with systolic heart failure, irrespective of symptomatic severity or blood pressure. ACE
Management_of_heart_failure
Chemical compound
recommended for patients with a history of pulmonary edema with the usage of ACE inhibitors.[citation needed] Sacubitril is a prodrug that is activated to sacubitrilat
Sacubitril
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