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Class of drugs
Nitazenes are a chemically defined class of substances derived from the parent compound nitazene. Nitazenes were developed in the second half of the 1950s
Nitazenes
Class of synthetic opioids
1-(β-diethylaminoethyl)-2-benzylbenzimidazole (desnitazene). Shortly afterwards, the nitazenes were discovered in structure-activity relationship studies. Relative analgesic
Benzimidazole_opioids
Recreational drug
cannabinoids and/or nitazene based synthetic opioids. Some samples contained just synthetic cannabinoids, some samples contained just nitazenes, and some samples
Kush_(drug)
Pharmaceutical compound
that nitazenes are uniformly harmful and suggest that safer, improved analgesics may exist among lower-potency or strategically modified nitazene derivatives
N-Desethylfluornitrazene
controls on earlier families of synthetic opioids such as fentanyls and nitazenes. Orphines are not structural analogues of morphine (known as morphinans)
List_of_orphine_opioids
Designer drugs are structural or functional analogues of controlled substances that are designed to mimic the pharmacological effects of the parent drug
List_of_designer_drugs
Chemical compound
of just two nitazenes that was banned in the UK since 1971, the other being clonitazene, as these were included in UN conventions. Nitazenes were not seen
Etonitazene
Pharmaceutical compound
PMC 11655282. PMID 39521025. Vandeputte MM, Stove CP (2025). "Navigating nitazenes: A pharmacological and toxicological overview of new synthetic opioids
Α'-Methyletonitazene
Chemical compound (analgesic drug)
doi:10.1007/bf02161116. PMID 13473817. S2CID 32179439. "Drug Trend Alert: Nitazenes" (PDF). Hamilton County Public Health. Hamilton County, Ohio. Retrieved
Metonitazene
Pharmaceutical compound
European Union Drugs Agency (EUDA). 14 May 2024. "Increasing availability of nitazenes calls for global response". Early Warning Advisory (EWA). United Nations
Fluetonitazene
Pharmaceutical compound
et al. (April 2024). "Pharmacologic Characterization of Substituted Nitazenes at μ, κ, and Δ Opioid Receptors Suggests High Potential for Toxicity"
Propylnitazene
Substance that arouses sexual desires
blockers: Gabapentinoids Opioids/μ-opioid receptor agonists: Benzimidazoles Nitazenes Fentanyl analogues/phenylpiperidines Mitragyna alkaloids Morphinans/phenanthrenes
Aphrodisiac
Atypical opioid drug
methadone, buprenorphine, prescription opioids, synthetic opioids like nitazenes, and kratom, among others. SR-17018 itself is said to produce minimal
SR-17018
Class of recreational drugs
cannabinoids identified for the first time in 2020. Since 2019, highly potent nitazenes (benzimidazole opioids) have proliferated as "new synthetic opioids" in
Designer_drug
Comparison of equivalent doses of pain medications
Cohen L (September 2024). Namm A, Crowdy A (eds.). "THE EMERGENCE OF NITAZENES IN THE AMERICAS". Inter-American Drug Abuse Control Commission. Information
Equianalgesic
Obsolete sedative–hypnotic drug
blockers: Gabapentinoids Opioids/μ-opioid receptor agonists: Benzimidazoles Nitazenes Fentanyl analogues/phenylpiperidines Mitragyna alkaloids Morphinans/phenanthrenes
Methaqualone
Chemical compound
Isotonitazene is a synthetic opioid analgesic drug from the nitazene class and structural homolog of etonitazene, which has been sold as a designer drug
Isotonitazene
Chemical compound
Metz TO, Rodda KE (July 2024). "Elucidating the Gas-Phase Behavior of Nitazene Analog Protomers Using Structures for Lossless Ion Manipulations Ion Mobility-Orbitrap
Secbutonitazene
Chemical compound
to curb rising synthetic drugs threat". GOV.UK. Retrieved 2025-06-12. "Nitazenes detected in fake oxycodone tablets in Europe and the UK – Reagent Tests
Isotonitazepyne
Class of chemical compounds
blockers: Gabapentinoids Opioids/μ-opioid receptor agonists: Benzimidazoles Nitazenes Fentanyl analogues/phenylpiperidines Mitragyna alkaloids Morphinans/phenanthrenes
Catecholamine
Tropane alkaloid and stimulant drug
blockers: Gabapentinoids Opioids/μ-opioid receptor agonists: Benzimidazoles Nitazenes Fentanyl analogues/phenylpiperidines Mitragyna alkaloids Morphinans/phenanthrenes
Cocaine
Opioid analgesic compound
blockers: Gabapentinoids Opioids/μ-opioid receptor agonists: Benzimidazoles Nitazenes Fentanyl analogues/phenylpiperidines Mitragyna alkaloids Morphinans/phenanthrenes
Mitragynine
Drug that reduces excitement without inducing sleep
blockers: Gabapentinoids Opioids/μ-opioid receptor agonists: Benzimidazoles Nitazenes Fentanyl analogues/phenylpiperidines Mitragyna alkaloids Morphinans/phenanthrenes
Sedative
blockers: Gabapentinoids Opioids/μ-opioid receptor agonists: Benzimidazoles Nitazenes Fentanyl analogues/phenylpiperidines Mitragyna alkaloids Morphinans/phenanthrenes
List of methaqualone analogues
List_of_methaqualone_analogues
Class of analgesic drug
Metodesnitazene (Metazene) Etodesnitazene (Etazene) Etonitazepyne Etonitazepipne Nitazene opioids, which are a subgroup of benzimidazoles opioids Metonitazene Etonitazene
Opioid
Class of compounds based upon the amphetamine structure
blockers: Gabapentinoids Opioids/μ-opioid receptor agonists: Benzimidazoles Nitazenes Fentanyl analogues/phenylpiperidines Mitragyna alkaloids Morphinans/phenanthrenes
Substituted_amphetamine
Chemical compound
(21 June 2023). "Old Drugs and New Challenges: A Narrative Review of Nitazenes". Cureus. 15 (6) e40736. doi:10.7759/cureus.40736. PMC 10361140. PMID 37485167
N-Desethyletonitazene
Drug whose use induces sleep
blockers: Gabapentinoids Opioids/μ-opioid receptor agonists: Benzimidazoles Nitazenes Fentanyl analogues/phenylpiperidines Mitragyna alkaloids Morphinans/phenanthrenes
Hypnotic
Pharmaceutical compound
17 August 2025. "Rapid Action Drug Alerts and Response (RADAR) Alert: Nitazenes". Public Health Scotland. NHS Scotland. 12 August 2025. Retrieved 17 August
Protodesnitazene
Gamma-aminobutyric acid analog
blockers: Gabapentinoids Opioids/μ-opioid receptor agonists: Benzimidazoles Nitazenes Fentanyl analogues/phenylpiperidines Mitragyna alkaloids Morphinans/phenanthrenes
Gabapentin
Chemical compound
blockers: Gabapentinoids Opioids/μ-opioid receptor agonists: Benzimidazoles Nitazenes Fentanyl analogues/phenylpiperidines Mitragyna alkaloids Morphinans/phenanthrenes
Α-Methyltryptamine
Chemical compound
blockers: Gabapentinoids Opioids/μ-opioid receptor agonists: Benzimidazoles Nitazenes Fentanyl analogues/phenylpiperidines Mitragyna alkaloids Morphinans/phenanthrenes
Phenmetrazine
Psychoactive substance that induces spiritual experiences
blockers: Gabapentinoids Opioids/μ-opioid receptor agonists: Benzimidazoles Nitazenes Fentanyl analogues/phenylpiperidines Mitragyna alkaloids Morphinans/phenanthrenes
Entheogen
cannabis, mixed with nitazene derivatives, tramadol and formaldehyde. In Sierra Leone in 2024, 83% of the Kush samples contained nitazenes, which are powerful
Opioid addiction in West Africa
Opioid_addiction_in_West_Africa
1991 book by Alexander Shulgin and Ann Shulgin
blockers: Gabapentinoids Opioids/μ-opioid receptor agonists: Benzimidazoles Nitazenes Fentanyl analogues/phenylpiperidines Mitragyna alkaloids Morphinans/phenanthrenes
PiHKAL
Chemical class of organic compounds
blockers: Gabapentinoids Opioids/μ-opioid receptor agonists: Benzimidazoles Nitazenes Fentanyl analogues/phenylpiperidines Mitragyna alkaloids Morphinans/phenanthrenes
Substituted_phenethylamine
Chemical compound
blockers: Gabapentinoids Opioids/μ-opioid receptor agonists: Benzimidazoles Nitazenes Fentanyl analogues/phenylpiperidines Mitragyna alkaloids Morphinans/phenanthrenes
5-Methoxytryptamine
Central nervous system stimulant
blockers: Gabapentinoids Opioids/μ-opioid receptor agonists: Benzimidazoles Nitazenes Fentanyl analogues/phenylpiperidines Mitragyna alkaloids Morphinans/phenanthrenes
Caffeine
Chemical compound
relationships and forensic case series of emerging 2-benzylbenzimidazole 'nitazene' opioids" (PDF). Archives of Toxicology. 98 (9). Springer Science and Business
N-Desethylprotonitazene
Chemical compound
blockers: Gabapentinoids Opioids/μ-opioid receptor agonists: Benzimidazoles Nitazenes Fentanyl analogues/phenylpiperidines Mitragyna alkaloids Morphinans/phenanthrenes
Ergine
Chemical compound
2022). "Intoxications in an Australian Emergency Department Involving 'Nitazene' Benzylbenzimidazole Synthetic Opioids (Etodesnitazene, Butonitazene and
Protonitazene
Central nervous system stimulant
blockers: Gabapentinoids Opioids/μ-opioid receptor agonists: Benzimidazoles Nitazenes Fentanyl analogues/phenylpiperidines Mitragyna alkaloids Morphinans/phenanthrenes
Methylphenidate
Chemical compound
blockers: Gabapentinoids Opioids/μ-opioid receptor agonists: Benzimidazoles Nitazenes Fentanyl analogues/phenylpiperidines Mitragyna alkaloids Morphinans/phenanthrenes
Azepino(4,5-b)indole
Opioid analgesic
analgesic of approximately three times the potency of morphine. It is in the nitazene family of benzimidazoles related to etonitazene, an opioid of significantly
Clonitazene
Class of depressant drugs derived from barbituric acid
blockers: Gabapentinoids Opioids/μ-opioid receptor agonists: Benzimidazoles Nitazenes Fentanyl analogues/phenylpiperidines Mitragyna alkaloids Morphinans/phenanthrenes
Barbiturate
Dried latex of the opium poppy containing narcotic compounds
blockers: Gabapentinoids Opioids/μ-opioid receptor agonists: Benzimidazoles Nitazenes Fentanyl analogues/phenylpiperidines Mitragyna alkaloids Morphinans/phenanthrenes
Opium
Compound intended to improve cognitive function
blockers: Gabapentinoids Opioids/μ-opioid receptor agonists: Benzimidazoles Nitazenes Fentanyl analogues/phenylpiperidines Mitragyna alkaloids Morphinans/phenanthrenes
Nootropic
Chemical compound
blockers: Gabapentinoids Opioids/μ-opioid receptor agonists: Benzimidazoles Nitazenes Fentanyl analogues/phenylpiperidines Mitragyna alkaloids Morphinans/phenanthrenes
1-Aminoindane
Pharmaceutical compound
Sutherland R, Sadaphale V, Barratt M, Bruno R, et al. (2025). Availability of nitazenes for purchase in Australia and internationally via cryptomarkets, September
Isotodesnitazene
Pharmaceutical compound
invented in the late 1950s as part of the original research into the "nitazene" group of opioids by CIBA in Switzerland, but as with all compounds from
Methionitazene
Class of medications used to alleviate anxiety
blockers: Gabapentinoids Opioids/μ-opioid receptor agonists: Benzimidazoles Nitazenes Fentanyl analogues/phenylpiperidines Mitragyna alkaloids Morphinans/phenanthrenes
Anxiolytic
Class of indoles
blockers: Gabapentinoids Opioids/μ-opioid receptor agonists: Benzimidazoles Nitazenes Fentanyl analogues/phenylpiperidines Mitragyna alkaloids Morphinans/phenanthrenes
Substituted_tryptamine
Trace amine
blockers: Gabapentinoids Opioids/μ-opioid receptor agonists: Benzimidazoles Nitazenes Fentanyl analogues/phenylpiperidines Mitragyna alkaloids Morphinans/phenanthrenes
Tryptamine
Pharmaceutical compound
"Mass Fragmentation Characteristics of New Psychoactive Substances of Nitazenes". Journal of Chinese Mass Spectrometry Society. 46 (3): 334–342. doi:10
Menitazene
Class of CNS depressant drugs
blockers: Gabapentinoids Opioids/μ-opioid receptor agonists: Benzimidazoles Nitazenes Fentanyl analogues/phenylpiperidines Mitragyna alkaloids Morphinans/phenanthrenes
Benzodiazepine
Stimulant and NDRI drug
blockers: Gabapentinoids Opioids/μ-opioid receptor agonists: Benzimidazoles Nitazenes Fentanyl analogues/phenylpiperidines Mitragyna alkaloids Morphinans/phenanthrenes
Prolintane
Class of chemical compounds
blockers: Gabapentinoids Opioids/μ-opioid receptor agonists: Benzimidazoles Nitazenes Fentanyl analogues/phenylpiperidines Mitragyna alkaloids Morphinans/phenanthrenes
DOx
Index of chemical compounds with the same name
blockers: Gabapentinoids Opioids/μ-opioid receptor agonists: Benzimidazoles Nitazenes Fentanyl analogues/phenylpiperidines Mitragyna alkaloids Morphinans/phenanthrenes
Methylxanthines
Parasympathetic nervous system inhibitors
blockers: Gabapentinoids Opioids/μ-opioid receptor agonists: Benzimidazoles Nitazenes Fentanyl analogues/phenylpiperidines Mitragyna alkaloids Morphinans/phenanthrenes
Anticholinergic
Chemical group (>N–C(=O)–O–)
blockers: Gabapentinoids Opioids/μ-opioid receptor agonists: Benzimidazoles Nitazenes Fentanyl analogues/phenylpiperidines Mitragyna alkaloids Morphinans/phenanthrenes
Carbamate
Species of plant
blockers: Gabapentinoids Opioids/μ-opioid receptor agonists: Benzimidazoles Nitazenes Fentanyl analogues/phenylpiperidines Mitragyna alkaloids Morphinans/phenanthrenes
Mitragyna_speciosa
Weight loss medication
blockers: Gabapentinoids Opioids/μ-opioid receptor agonists: Benzimidazoles Nitazenes Fentanyl analogues/phenylpiperidines Mitragyna alkaloids Morphinans/phenanthrenes
Phentermine
Chemical compound
Characterization, and μ-Opioid Receptor Activity Assessment of the Emerging Group of "Nitazene" 2-Benzylbenzimidazole Synthetic Opioids". ACS Chemical Neuroscience. 12
N-Desethylisotonitazene
Chemical compound
blockers: Gabapentinoids Opioids/μ-opioid receptor agonists: Benzimidazoles Nitazenes Fentanyl analogues/phenylpiperidines Mitragyna alkaloids Morphinans/phenanthrenes
Pyrazolopyrimidine
Group of psychedelic drugs
blockers: Gabapentinoids Opioids/μ-opioid receptor agonists: Benzimidazoles Nitazenes Fentanyl analogues/phenylpiperidines Mitragyna alkaloids Morphinans/phenanthrenes
TWEETIO
Monoamine neurotransmitter
blockers: Gabapentinoids Opioids/μ-opioid receptor agonists: Benzimidazoles Nitazenes Fentanyl analogues/phenylpiperidines Mitragyna alkaloids Morphinans/phenanthrenes
Serotonin
Chemical compound
blockers: Gabapentinoids Opioids/μ-opioid receptor agonists: Benzimidazoles Nitazenes Fentanyl analogues/phenylpiperidines Mitragyna alkaloids Morphinans/phenanthrenes
Α-Ethyltryptamine
Device that vaporizes a liquid nicotine solution for inhalation
as methamphetamine and cocaine, opioids such as fentanyl analogs and nitazenes, a wide variety of synthetic cannabinoids as well as semi-synthetic cannabinoids
Electronic_cigarette
Heterocyclic compound containing a ring of four carbon, one nitrogen and one sulfur atom
blockers: Gabapentinoids Opioids/μ-opioid receptor agonists: Benzimidazoles Nitazenes Fentanyl analogues/phenylpiperidines Mitragyna alkaloids Morphinans/phenanthrenes
Phenothiazine
Psychoactive stimulant
blockers: Gabapentinoids Opioids/μ-opioid receptor agonists: Benzimidazoles Nitazenes Fentanyl analogues/phenylpiperidines Mitragyna alkaloids Morphinans/phenanthrenes
Methcathinone
Class of chemical compounds
blockers: Gabapentinoids Opioids/μ-opioid receptor agonists: Benzimidazoles Nitazenes Fentanyl analogues/phenylpiperidines Mitragyna alkaloids Morphinans/phenanthrenes
Partial_lysergamide
Compounds that alter neuronal activity
blockers: Gabapentinoids Opioids/μ-opioid receptor agonists: Benzimidazoles Nitazenes Fentanyl analogues/phenylpiperidines Mitragyna alkaloids Morphinans/phenanthrenes
Neurosteroid
Entactogen, stimulant, and psychedelic drug of the amphetamine family
blockers: Gabapentinoids Opioids/μ-opioid receptor agonists: Benzimidazoles Nitazenes Fentanyl analogues/phenylpiperidines Mitragyna alkaloids Morphinans/phenanthrenes
3,4-Methylenedioxyamphetamine
Group of alkaloids related to Tabernanthe iboga
blockers: Gabapentinoids Opioids/μ-opioid receptor agonists: Benzimidazoles Nitazenes Fentanyl analogues/phenylpiperidines Mitragyna alkaloids Morphinans/phenanthrenes
Iboga-type_alkaloid
Short-acting anaesthetic and sedative drug
cannabis, synthetic cannabinoids, ketamine, designer benzodiazepines, and nitazene-derived opioid drugs. By early 2025, use of etomidate vapes and associated
Etomidate
Class of pharmaceutical drugs
blockers: Gabapentinoids Opioids/μ-opioid receptor agonists: Benzimidazoles Nitazenes Fentanyl analogues/phenylpiperidines Mitragyna alkaloids Morphinans/phenanthrenes
Tetracyclic_antidepressant
Naturally occurring psychedelic compound
blockers: Gabapentinoids Opioids/μ-opioid receptor agonists: Benzimidazoles Nitazenes Fentanyl analogues/phenylpiperidines Mitragyna alkaloids Morphinans/phenanthrenes
Mescaline
Compounds found in cannabis
blockers: Gabapentinoids Opioids/μ-opioid receptor agonists: Benzimidazoles Nitazenes Fentanyl analogues/phenylpiperidines Mitragyna alkaloids Morphinans/phenanthrenes
Cannabinoid
Hallucinogenic class of psychoactive drug
blockers: Gabapentinoids Opioids/μ-opioid receptor agonists: Benzimidazoles Nitazenes Fentanyl analogues/phenylpiperidines Mitragyna alkaloids Morphinans/phenanthrenes
Psychedelic_drug
Class of chemical compounds
blockers: Gabapentinoids Opioids/μ-opioid receptor agonists: Benzimidazoles Nitazenes Fentanyl analogues/phenylpiperidines Mitragyna alkaloids Morphinans/phenanthrenes
FLY_(psychedelics)
Chemical compound
blockers: Gabapentinoids Opioids/μ-opioid receptor agonists: Benzimidazoles Nitazenes Fentanyl analogues/phenylpiperidines Mitragyna alkaloids Morphinans/phenanthrenes
Ethylenediamine
Entactogen drug
blockers: Gabapentinoids Opioids/μ-opioid receptor agonists: Benzimidazoles Nitazenes Fentanyl analogues/phenylpiperidines Mitragyna alkaloids Morphinans/phenanthrenes
MMDA_(drug)
Medication used to treat mental disorders
blockers: Gabapentinoids Opioids/μ-opioid receptor agonists: Benzimidazoles Nitazenes Fentanyl analogues/phenylpiperidines Mitragyna alkaloids Morphinans/phenanthrenes
Psychiatric_medication
Chemical compound
review of the evidence on the use and harms of 2-benzyl benzimidazole ('nitazene') and piperidine benzimidazolone ('brorphine-like') opioids" (PDF). UK:
Etoacetazene
Class of organic compounds
blockers: Gabapentinoids Opioids/μ-opioid receptor agonists: Benzimidazoles Nitazenes Fentanyl analogues/phenylpiperidines Mitragyna alkaloids Morphinans/phenanthrenes
Alcohol_(chemistry)
Psychiatric medication used to treat mood disorders
blockers: Gabapentinoids Opioids/μ-opioid receptor agonists: Benzimidazoles Nitazenes Fentanyl analogues/phenylpiperidines Mitragyna alkaloids Morphinans/phenanthrenes
Mood_stabilizer
notorious kingpin, the relatively unknown Jalen Turner, who has been supplying nitazene. After staging a robbery of Turner's supply, Eva goes to meet him with
List_of_FBI_episodes
Class of chemical compounds
blockers: Gabapentinoids Opioids/μ-opioid receptor agonists: Benzimidazoles Nitazenes Fentanyl analogues/phenylpiperidines Mitragyna alkaloids Morphinans/phenanthrenes
1,2-Diarylethylamine
Pharmaceutical compound
blockers: Gabapentinoids Opioids/μ-opioid receptor agonists: Benzimidazoles Nitazenes Fentanyl analogues/phenylpiperidines Mitragyna alkaloids Morphinans/phenanthrenes
2C-H
Class of medications
blockers: Gabapentinoids Opioids/μ-opioid receptor agonists: Benzimidazoles Nitazenes Fentanyl analogues/phenylpiperidines Mitragyna alkaloids Morphinans/phenanthrenes
Antipsychotic
Chemical compound
blockers: Gabapentinoids Opioids/μ-opioid receptor agonists: Benzimidazoles Nitazenes Fentanyl analogues/phenylpiperidines Mitragyna alkaloids Morphinans/phenanthrenes
Naphthylaminopropane
Chemical compound
blockers: Gabapentinoids Opioids/μ-opioid receptor agonists: Benzimidazoles Nitazenes Fentanyl analogues/phenylpiperidines Mitragyna alkaloids Morphinans/phenanthrenes
Benzimidazole
Psychoactive drug
blockers: Gabapentinoids Opioids/μ-opioid receptor agonists: Benzimidazoles Nitazenes Fentanyl analogues/phenylpiperidines Mitragyna alkaloids Morphinans/phenanthrenes
Ariadne_(drug)
Carbamate derivative used as an anxiolytic
blockers: Gabapentinoids Opioids/μ-opioid receptor agonists: Benzimidazoles Nitazenes Fentanyl analogues/phenylpiperidines Mitragyna alkaloids Morphinans/phenanthrenes
Meprobamate
Chemical compound
"Acute Intoxications and Fatalities Associated With Benzimidazole Opioid (Nitazene Analog) Use: A Systematic Review". Therapeutic Drug Monitoring. 44 (4):
Etonitazepyne
Chemical compound
blockers: Gabapentinoids Opioids/μ-opioid receptor agonists: Benzimidazoles Nitazenes Fentanyl analogues/phenylpiperidines Mitragyna alkaloids Morphinans/phenanthrenes
Thienotriazolodiazepine
Active ingredient in fermented drinks
blockers: Gabapentinoids Opioids/μ-opioid receptor agonists: Benzimidazoles Nitazenes Fentanyl analogues/phenylpiperidines Mitragyna alkaloids Morphinans/phenanthrenes
Alcohol_(drug)
Class of drugs
blockers: Gabapentinoids Opioids/μ-opioid receptor agonists: Benzimidazoles Nitazenes Fentanyl analogues/phenylpiperidines Mitragyna alkaloids Morphinans/phenanthrenes
Racetam
Drug that increases wakefulness
blockers: Gabapentinoids Opioids/μ-opioid receptor agonists: Benzimidazoles Nitazenes Fentanyl analogues/phenylpiperidines Mitragyna alkaloids Morphinans/phenanthrenes
Wakefulness-promoting_agent
Polycyclic aromatic hydrocarbon composed of three fused benzene rings
blockers: Gabapentinoids Opioids/μ-opioid receptor agonists: Benzimidazoles Nitazenes Fentanyl analogues/phenylpiperidines Mitragyna alkaloids Morphinans/phenanthrenes
Phenanthrene
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