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Drug that reduces excitement without inducing sleep
A sedative, or tranquilizer, is a substance that induces sedation by reducing irritability or excitement. They are central nervous system (CNS) depressants
Sedative
Drug whose use induces sleep
fibromyalgia as well. This group of drugs is related to sedatives. Whereas the term sedative describes drugs that serve to calm or relieve anxiety, the
Hypnotic
of sedative, hypnotic or anxiolytic Harmful pattern of use of sedative, hypnotic or anxiolytic Sedative, hypnotic or anxiolytic dependence Sedative, hypnotic
List_of_mental_disorders
Australian band
Sedative is an Australian deathcore band from Perth, formed in 2021. The band currently consists of vocalist Matthew Daly (Blanche Dubrah),guitarists Benjamin
Sedative_(band)
Benzodiazepine medication
carbamazepine, sedative antihistamines, opiates, antipsychotics, and alcohol, when taken with lorazepam may result in enhanced sedative effects. Signs
Lorazepam
Obsolete sedative–hypnotic drug
Methaqualone is a sedative-hypnotic medication that was widely prescribed during the mid-20th century. It was marketed under various brand names, including
Methaqualone
Class of depressant drugs derived from barbituric acid
effects. They have been used recreationally for their anti-anxiety and sedative effects, and are thus controlled in most countries due to the risks associated
Barbiturate
Syndrome caused by a dangerous level of a toxin
Substances that may cause this toxidrome are opioids. The symptoms of sedative/hypnotic toxidrome include ataxia, blurred vision, coma, confusion, delirium
Toxidrome
Non-lethal gun used to deliver sedatives and medications animals
with a hypodermic needle and filled with a sedative, vaccine or antibiotic. A dart gun containing a sedative is called a tranquillizer gun (also spelled
Dart_gun
American singer and actor (1935–1977)
eight months of 1977 alone, he had [prescribed] more than 10,000 doses of sedatives, amphetamines, and narcotics: all in Elvis' name." Nichopoulos' license
Elvis_Presley
Antihistamine medication
sold under the brand name Benadryl among others, is an antihistamine and sedative. Although generally considered sedating, diphenhydramine can cause paradoxical
Diphenhydramine
Medical condition
neurological condition which results from repeated withdrawal episodes from sedative–hypnotic drugs such as alcohol and benzodiazepines. Each withdrawal leads
Kindling (sedative–hypnotic withdrawal)
Kindling_(sedative–hypnotic_withdrawal)
disorder NOS 304.10 Sedative, hypnotic, or anxiolytic dependence 305.40 Sedative, hypnotic, or anxiolytic abuse 292.89 Sedative, hypnotic, or anxiolytic
List of mental disorders in the DSM-IV and DSM-IV-TR
List_of_mental_disorders_in_the_DSM-IV_and_DSM-IV-TR
2026 film by Nia DaCosta
sacrifice to Old Nick, claiming that Satan is his father. Running low on sedatives, Kelson prepares to euthanise Samson, but is overjoyed when Samson says
28 Years Later: The Bone Temple
28_Years_Later:_The_Bone_Temple
Chemical compound
allylisopropylacetylurea or allylisopropylacetylcarbamide, is a hypnotic/sedative drug of the ureide (acylurea) group synthesized in 1926 by Hoffmann-La
Apronal
Triazolobenzodiazepine sleep medication
generally only used as a sedative to treat severe insomnia. In addition to the hypnotic properties, triazolam's amnesic, anxiolytic, sedative, anticonvulsant,
Triazolam
Sedative-hypnotic drug
Ethchlorvynol is a GABAA receptor positive allosteric modulator with hypnotic and sedative properties, first developed by Pfizer in the 1950s. In the United States
Ethchlorvynol
German philosopher (1844–1900)
while staying in Nice, he was writing out his own prescriptions for the sedative chloral hydrate, signing them "Dr. Nietzsche". He turned away from the
Friedrich_Nietzsche
Benzodiazepine drug
Marcen, Sedatival, Sedotime, Solatran and Unakalm) is a drug which is a benzodiazepine derivative. It possesses anxiolytic, anticonvulsant, sedative and skeletal
Ketazolam
American singer-songwriter (born 1948)
that she might relapse, she visited a psychiatrist, who prescribed the sedative Klonopin to help her remain free from cocaine. In late 1985, Fleetwood
Stevie_Nicks
Benzodiazepine medication
temazepam, and has moderate amnesic, anxiolytic, anticonvulsant, hypnotic, sedative, and skeletal muscle relaxant properties compared to other benzodiazepines
Oxazepam
Benzodiazepine medication
Chlordiazepoxide hydrochloride, sold under the brand name Librium, is a sedative and hypnotic medication of the benzodiazepine class. It is used to treat
Chlordiazepoxide
Chemical sedative and hypnotic drug
is a geminal diol with the formula Cl3C−CH(OH)2. It was first used as a sedative and hypnotic in Germany in the 1870s. Over time it was replaced by safer
Chloral_hydrate
Alpha-adrenergic agonist
Kapvay, among others, is an α2-adrenergic receptor agonist, hypotensive, sedative and anxiolytic drug used to treat high blood pressure, attention deficit
Clonidine
as qualones, are a group of 4-quinazolinone derivatives typified by the sedative and hypnotic drug methaqualone (former brand name Quaalude). They are known
List of methaqualone analogues
List_of_methaqualone_analogues
Barbiturate
anxiolytic, sedative, and hypnotic properties. In the United Kingdom, it was known as quinalbarbitone. Secobarbital is considered to be an obsolete sedative–hypnotic
Secobarbital
Medical condition
tolerance reported that "tolerance develops relatively quickly for the sedative and anticonvulsant actions of benzodiazepines, whereas tolerance to anxiolytic
Benzodiazepine_dependence
German physician
suspicion. Josef von Mering helped to discover barbiturates, a class of sedative drugs used for insomnia, epilepsy, anxiety, and anesthesia. In 1903, he
Joseph_von_Mering
Group of chemical compounds
bioactive. They are responsible for the psychoactive, analgesic, euphoric and sedative effects of kava. Kava extract interacts with many pharmaceuticals and herbal
Kavalactone
Species of plant
the Lactuca (lettuce) genus, often ingested for its mild analgesic and sedative effects. It is related to common lettuce (L. sativa), and is often called
Lactuca_virosa
American track and field hurdle athlete (1959–1998)
acetominophen and the antihistamine Benadryl, which is sometimes used as a mild sedative. "USATF - Hall of Fame". usatf.org. Archived from the original on September
Florence_Griffith_Joyner
Sedative/Hypnotic medication for alcohol withdrawal
Clomethiazole (also called chlormethiazole) is a sedative and hypnotic originally developed by Hoffmann-La Roche in the 1930s. The drug is typically used
Clomethiazole
Muscle relaxant medication
effects and safety profile associated with baclofen when it is combined with sedative drugs (e.g., alcohol, barbiturates, and benzodiazepines) range depending
Baclofen
Chemical compound
nervous system (CNS) depressant drug developed in 1949 as a nonbarbiturate sedative-hypnotic. It was marketed under various trade names, including Presidon
Pyrithyldione
Class of drugs
Many GABA analogues are used as drugs, especially as anticonvulsants, sedatives, and anxiolytics. Butyric acid (butanoic acid) – histone deacetylase inhibitor
GABA_analogue
Nykopp-Koski Finland 2004–2009 5 Nurse who killed five elderly patients using sedatives and opiates in Finland. Kimberly Clark Saenz United States 2008 5 Killed
List of serial killers by number of victims
List_of_serial_killers_by_number_of_victims
Antihistamine drug
tract.[better source needed] Use of hydroxyzine for premedication as a sedative has no effects on tropane alkaloids, such as atropine, but may, following
Hydroxyzine
Opium-based sedative in Victorian Britain
laudanum (tincture of opium) in a sweet syrup, which was commonly used as a sedative to quiet infants and children in Victorian England. Used mostly by mothers
Godfrey's_Cordial
Alcoholic drink created for sharing
began to treat afflicted soldiers with large doses of a sedative called sodium amytal. The sedative would induce a deep sleep lasting up to three weeks.
Jungle_juice
Chemical compound
Prenderol (Diethylpropanediol) is a simple alkyl diol which has sedative, anticonvulsant and muscle relaxant effects. It is closely related in structure
Prenderol
Crown Prince of Saudi Arabia since 2017
seeks death penalty for Khashoggi murder, says journalist was killed by sedative overdose". CNN. 15 November 2018. Archived from the original on 15 November
Mohammed_bin_Salman
Allergy medication
antagonist (antihistamine) with anticholinergic properties (drying) and sedative side effects. Like all first-generation antihistamines, it is sedating
Clemastine
Benzodiazepine medication
a benzodiazepine medication. It possesses anxiolytic, anticonvulsant, sedative, hypnotic, and skeletal muscle relaxant properties. Clorazepate is an unusually
Clorazepate
Short-acting barbiturate
Pentobarbital is a short-acting barbiturate typically used as a sedative, a preanesthetic, and to control convulsions in emergencies. It can also be used
Pentobarbital
Chemical compound
depressant and was soon found to be an effective anticonvulsant, hypnotic and sedative. It was included in some cough medicines as an expectorant (though there
Paraldehyde
Birth defects linked to thalidomide use
trouble sleeping, tension, and morning sickness. It was introduced as a sedative and medication for morning sickness without having been tested on pregnant
Thalidomide_scandal
Pharmaceutical compound
MCPPQ, is an analogue of the sedative and hypnotic drug methaqualone which has been sold as a designer drug. It is one of a number of "next generation"
MCPPQ
Topics referred to by the same term
drug with typical sedative and anxiolytic effects Ro5-4864, or 4'-Chlorodiazepam, an atypical benzodiazepine derivative with sedative yet also convulsant
Chlorodiazepam
Antidopaminergic drug
nausea) and as an antipsychotic. Droperidol is also often used as a rapid sedative in intensive-care treatment, and where "agitation aggression or violent
Droperidol
Medical condition
differential diagnosis should include intoxication by other substances with sedative effects, such as benzodiazepines, anticonvulsants (carbamazepine), alcohols
Barbiturate_overdose
Benzodiazepine drug
anxiolytic effects, yet without any notable sedative or amnestic effects. In fact, imidazenil blocks the sedative effects of diazepam, yet without lowering
Imidazenil
Spice Effect Aniseed anti-spasmodic, expectorant, sedative Caraway diuretic, anti-spasmodic, galactagogue Cardamom antiseptic Cilantro antibacterial, anti-inflammatory
Spice_use_in_antiquity
King of the United Kingdom from 1910 to 1936
you!", were addressed to his nurse, Catherine Black, when she gave him a sedative that night. Dawson, who supported the gentle growth of euthanasia in the
George_V
American musician (1964–2017)
prescription medications in therapeutic doses were found in Cornell's system: the sedative butalbital (5.4 μg/mL), commonly prescribed for the treatment of headache;
Chris_Cornell
Pharmaceutical compound
also known as 5-phenyl-3-methylpyrazole, is a sedative drug and arylpyrazole derivative. It produces sedative, hypnotic, hypolocomotive, antiaggressive,
Phemerazole
Experimental psychiatric drug
modulator with a wider separation between antidepressant-like activity and sedative effects in preclinical research than related drugs like zuranolone. It
PRAX-114
Sedation of the terminally ill
usually by means of a continuous intravenous or subcutaneous infusion of a sedative drug, or by means of a specialized catheter designed to provide comfortable
Palliative_sedation
Chemical compound
Lactucopicrin (Intybin) is a bitter substance that has a sedative and analgesic effect, acting on the central nervous system. It is a sesquiterpene lactone
Lactucopicrin
Spray that delivers medications locally in the nasal cavities or systemically
pharmaceutical drugs exist as nasal sprays for systemic administration (e.g. sedative-analgesics, treatments for migraine, osteoporosis and nausea). Other applications
Nasal_spray
Medical condition
(1995) study found oxazepam less toxic and less sedative, and temazepam more toxic and more sedative, than most benzodiazepines in overdose. Following
Benzodiazepine_overdose
Pharmaceutical compound
is an analogue of the sedative and hypnotic drug methaqualone first synthesised in the 1980s, though not identified as a sedative drug until 2020. It is
PPQ_(drug)
Reduction of irritability or agitation by administration of sedative drugs
Sedation is the reduction of irritability or agitation by administration of sedative drugs, generally to facilitate a medical procedure or diagnostic procedure
Sedation
American serial killer (1960–1994)
administered sleeping pills to his partners, giving them liquor laced with sedatives. He then waited for his partner to fall asleep before performing various
Jeffrey_Dahmer
2023 Brazilian television series
about their time together. After the party, Joana secretly puts some sedatives in Sérgio's drink to avoid having sex with him. Lorraine and Kevin share
The Others (Brazilian TV series)
The_Others_(Brazilian_TV_series)
Chemical compound
Romifidine is a drug that is used in veterinary medicine as a sedative mainly in large animals such as horses, although it may be used in a wide variety
Romifidine
Hypnotic medication
positive allosteric modulation at GABAA neurons. Zopiclone is considered a sedative and CNS depressant. Zopiclone and other benzodiazepine-like drugs like
Zopiclone
Drink laced with drugs
and murderers at drinking establishments who lace alcoholic drinks with sedative drugs. The "Mickey Finn" is most likely named after the manager and bartender
Mickey_Finn_(drugs)
Triazolobenzodiazepine medication
with a triazole ring. It possesses anxiolytic, anticonvulsant, hypnotic, sedative and skeletal muscle relaxant properties. Estazolam is an intermediate-acting
Estazolam
Species of tree
antispasmodic (reduces smooth muscle spasm along the digestive tract), and sedative.[medical citation needed] The flowers were added to baths to quell hysteria
Tilia_americana
Medical intervention
assessment, determine any contraindications to PSA, choose the most appropriate sedative agent, and monitor the patient for potential complications both during
Procedural sedation and analgesia
Procedural_sedation_and_analgesia
Class of psychoactive drugs
drugs begin with the letter "z"), are a class of psychoactive, depressant, sedative, hypnotic, anxiolytic drugs that are benzodiazepine-like in uses. Nonbenzodiazepine
Nonbenzodiazepine
Medication used to treat anxiety disorders
antidepressant-induced sexual dysfunction, and bruxism. Buspirone is not effective as a sedative–hypnotic or muscle relaxant and does not have anticonvulsant properties
Buspirone
American singer-songwriter (born 1999)
whom misdiagnosed her with schizophrenia and gave her anti-psychotic sedatives that turned her into a "zombie", she was diagnosed with borderline personality
Madison_Beer
Veterinary anesthetic, sedative and analgesic
antihypertensive effects before being discontinued and marketed as a veterinary sedative. Xylazine's mechanism of action was discovered in 1981, which led to the
Xylazine
Chemical compound
Medetomidine is a veterinary anesthetic medication with potent sedative effects. As of December 2025[update], it is an emerging illicit drug adulterant
Medetomidine
Miles Laboratories sedative patent medicine (1884–ca.1970)
Nervine was a patent medicine tonic with sedative effects introduced in 1884 by Dr. Miles Medical Company (later Miles Laboratories which was absorbed
Nervine
Category of drug
an agonist for one or more of the GABA receptors, producing typically sedative effects, and may also cause other effects such as anxiolytic, anticonvulsant
GABA_receptor_agonist
Chemical compound
Probarbital (trade names Ipral, Vasalgin) is a barbiturate derivative invented in the 1920s. It has sedative, hypnotic and anticonvulsant properties. v t e
Probarbital
Craft toy
shipped toys, used a cheap chemical that was a pharmacologically active sedative prodrug instead of the safer chemical specified by the designers, resulting
Bindeez
2019 American thriller film
becomes distressed, is restrained by security and after being given a sedative is locked in a room. He escapes and waves down two police officers to who
Fractured_(2019_film)
Chemical compound
2-Methyl-2-propyl-1,3-propanediol (MPP) is a simple alkyl diol which has sedative, anticonvulsant and muscle relaxant effects. It is both a synthetic precursor
2-Methyl-2-propyl-1,3-propanediol
2-Methyl-2-propyl-1,3-propanediol
Sedating antihistamine
brand name Phenergan among others, is a first-generation antihistamine, sedative, and antiemetic used to treat allergies, nausea, and vomiting. It may also
Promethazine
Pharmaceutical compound
Mephenaqualone is an analogue of the sedative and hypnotic drug methaqualone which has been sold as a designer drug. It was reported in Germany in 2025
Mephenaqualone
Sedative medication
adults may reduce time to extubation and ICU stay. Compared with other sedatives, some studies suggest dexmedetomidine may be associated with less delirium
Dexmedetomidine
Discontinued medication
composed of the opioid analgesic drug tapentadol and the muscle relaxant and sedative drug carisoprodol within the same pill. It was manufactured by an Indian
Tafrodol
Chemical compound
has neuroprotective and anticonvulsant, anxiolytic, antinociceptive and sedative / hypnotic effects in animal models. Pilot human clinical trials in the
HA-966
Typical antipsychotic medication
the typical antipsychotics. Chlorpromazine and other antipsychotics with sedative properties such as promazine and thioridazine are among the most potent
Chlorpromazine
Chemical compound
marketed primarily in France and some other European countries. It has sedative, anxiolytic, antihistamine and analgesic properties, resulting from its
Diproqualone
Bromoureides are sedative-hypnotics available mainly in Europe and Asia, including acecarbromal, bromisoval, and carbromal (Horowitz, 1997). They are a
Bromoureide
Benzodiazepine derivative medication
derivatives, it has amnesic, anticonvulsant, anxiolytic, muscle relaxant, and sedative properties. However, it is used primarily in the treatment of anxiety disorders
Nordazepam
Class of CNS depressant drugs
neurotransmitter gamma-aminobutyric acid (GABA) at the GABAA receptor, resulting in sedative, hypnotic (sleep-inducing), anxiolytic (anti-anxiety), anticonvulsant,
Benzodiazepine
Chemical compound
JM-1232 is a sedative and hypnotic drug being researched as a potential anesthetic. It has similar effects to sedative-hypnotic benzodiazepine drugs,
JM-1232
Drug-induced relaxation of dental patients
and appropriate sedative measures while incorporating anxiety-reducing procedures. Adherence to safety protocols while performing sedative procedures in
Sedation_dentistry
Chemical compound
Petrichloral (pentaerythritol chloral, brand name Periclor) is a sedative and hypnotic chloral hydrate prodrug. It is a Schedule IV drug in the USA. US
Petrichloral
Medication used to treat insomnia
Zaleplon, sold under the brand name Sonata among others, is a sedative and hypnotic which is used to treat insomnia. It is a nonbenzodiazepine or Z-drug
Zaleplon
Chemical compound
anti-anxiety and sedative properties and is, in contrast to most barbiturates, almost without hypnotic action. It was used as a sedative and anti-anxiety
Proxibarbital
Triazolobenzodiazepine
is the bromo instead of chloro analogue of alprazolam and has similar sedative and anxiolytic effects to it and other benzodiazepines. Bromazolam is a
Bromazolam
Chemical compound
model and its acid parameters are EA = 0.85 and CA = 0.87. Octanol has a sedative and anesthetic effect in animal studies, though 1-octanol may not be the
1-Octanol
Class of chemical compounds formally derived from the acylation of urea
chlorphenacemide, and acetylpheneturide (which are phenylureides), and the sedatives acecarbromal, bromisoval, and carbromal (which are bromoureides). Others
Acylurea
Herbal tea made out of poppy straw or poppy seeds
narcotic effect, and in small amounts for analgesic, anti-diarrheal, and sedative effects. It has also been known to be used as a method of relieving withdrawal
Poppy_tea
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