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Nervous system disease affecting nerves beyond the brain and spinal cord
Peripheral neuropathy, often shortened to neuropathy, is damage or disease affecting the nerves. Damage to nerves may impair sensation, movement, gland
Peripheral_neuropathy
Neurological complication of persistently high blood sugar
Diabetic neuropathy includes various types of nerve damage associated with diabetes mellitus. The most common form, diabetic peripheral neuropathy, affects
Diabetic_neuropathy
Disorders of nerves outside the brain and spinal cord
Small fiber peripheral neuropathy is a type of peripheral neuropathy that results from damage to the small unmyelinated and myelinated peripheral nerve fibers
Small_fiber_neuropathy
Medical condition
Chemotherapy-induced peripheral neuropathy (CIPN) is a nerve-damaging side effect of antineoplastic agents in the common cancer treatment, chemotherapy
Chemotherapy-induced peripheral neuropathy
Chemotherapy-induced_peripheral_neuropathy
Medical condition
Hereditary neuropathy with liability to pressure palsy (HNPP) is a peripheral neuropathy, a condition that affects the nerves. Pressure on the nerves
Hereditary neuropathy with liability to pressure palsy
Hereditary_neuropathy_with_liability_to_pressure_palsy
Part of the nervous system excluding the brain and spinal cord
Commons has media related to Peripheral nervous system. Peripheral nervous system photomicrographs Peripheral Neuropathy Archived 2016-12-15 at the Wayback
Peripheral_nervous_system
Medical condition
out other causes of peripheral neuropathy. One of the first presenting symptoms of diabetes mellitus may be peripheral neuropathy, and hemoglobin A1C
Alcoholic_polyneuropathy
Medical condition
Anti-MAG peripheral neuropathy is a specific type of peripheral neuropathy in which the person's own immune system attacks cells that are specific in
Anti-MAG peripheral neuropathy
Anti-MAG_peripheral_neuropathy
SNRI medication
Whereas duloxetine has shown efficacy in treating painful diabetic peripheral neuropathy by blocking late Nav 1.7 sodium ion channels and increasing norepinephrine
Duloxetine
Pain affecting the somatosensory nervous system
identifying the underlying cause and relieving pain. In cases of peripheral neuropathy, the pain may progress to insensitivity. Up to 7–8% of the European
Neuropathic_pain
Anticonvulsant and analgesic medication
bipolar disorder, cocaine addiction, dementia, depression, diabetic peripheral neuropathy, fibromyalgia, headache, hiccups, Huntington's disease, mania, migraine
Lacosamide
Medical condition
response to the particles might have produced their mysterious peripheral neuropathy. These suspicions were confirmed in reports and investigations conducted
Progressive inflammatory neuropathy
Progressive_inflammatory_neuropathy
Insufficient level of copper in the body, leading to anaemia and nervous symptoms
variety of neurological problems including myelopathy, peripheral neuropathy, and optic neuropathy. Copper deficiency myelopathy in humans was discovered
Copper_deficiency
Medical condition
peripheral body, is diseased or damaged. Peripheral neuropathy is a general term that indicates any disorder of the peripheral nervous system. The name of the
Peripheral_mononeuropathy
Autoimmune disease affecting the peripheral nervous system
of neuropathy (e.g., hereditary, vasculitic) cannot be excluded, or when profound axonal involvement is observed on EMG. Ultrasound of the peripheral nerves
Chronic inflammatory demyelinating polyneuropathy
Chronic_inflammatory_demyelinating_polyneuropathy
Component of the neurological exam
Huntington's disease, essential tremors, atypical parkinsonism, peripheral neuropathies, and vestibulopathies. A person with an abnormal tandem gait does
Tandem_gait
Any disease affecting peripheral nerves on both sides of the body
and -pathy 'sickness') is damage or disease affecting peripheral nerves (peripheral neuropathy) in roughly the same areas on both sides of the body, featuring
Polyneuropathy
Disease of the ulnar nerve in the forearm
Ulnar neuropathy is a disorder involving the ulnar nerve. Ulnar neuropathy may be caused by entrapment of the ulnar nerve with resultant numbness and tingling
Ulnar_neuropathy
Medical condition
Severe swelling can cause permanent damage to nerves, resulting in peripheral neuropathy. Many cases from temporary or minor causes resolve on their own
Peripheral_edema
Medical condition
30 days, poor control over blood glucose levels, peripheral neuropathy, renal impairment, peripheral artery disease, injury or trauma to foot, walking
Diabetic_foot_infection
Topics referred to by the same term
Look up neuropathy in Wiktionary, the free dictionary. Neuropathy is a condition affecting the nerves of the peripheral nervous system. Neuropathy may also
Neuropathy_(disambiguation)
Medical condition
associated with systemic diseases (such as diabetes and renal disease), peripheral neuropathy, and psychiatric comorbidities (anxiety and depression), effective
Prurigo_nodularis
Treatment of cancer using drugs that inhibit cell division or kill cells
people undergoing chemotherapy experience chemotherapy-induced peripheral neuropathy (CIPN), a progressive, enduring, and often irreversible condition
Chemotherapy
Medical measurement of vibration perception
Diabetic Peripheral Neuropathy. In a systemic review of modern devices available for the assessment and screening of peripheral neuropathy, digital devices
Biothesiometry
Medical condition
of the calf. Rarely complications such as deep vein thrombosis, peripheral neuropathy, ischemia, or compartment syndrome may occur. Risk factors include
Baker's_cyst
Human disease
squash players during periods between matches. Crutch paralysis Peripheral neuropathy Han, Bo Ram; Cho, Yong Jun; Yang, Jin Seo; Kang, Suk Hyung; Choi
Radial_neuropathy
Syndrome marked by sensory neuropathy induced by excess vitamin B6
serious harm when taken in excess. The predominant symptom is peripheral sensory neuropathy that is experienced as numbness, pins-and-needles and burning
Megavitamin-B6_syndrome
Type of neurofibromatosis disease
[citation needed] The primary neurologic involvement in NF-1 is of the peripheral nervous system, and secondarily of the central nervous system. Schwannomatosis
Neurofibromatosis_type_I
Sensory neuropathy caused by damage of nerve cells in the dorsal root ganglion
neuronopathy (also known as sensory ganglionopathy) is a type of peripheral neuropathy that results primarily in sensory symptoms (such as parasthesias
Sensory_neuronopathy
Inflammation of a nerve or generally any part of the nervous system
conflated with neuropathy, a broad term describing any disease process which affects the peripheral nervous system. However, neuropathies may be due to
Neuritis
Neuromuscular disease
as hereditary motor and sensory neuropathy (HMSN), is an inherited neurological disorder that affects the peripheral nerves responsible for transmitting
Charcot–Marie–Tooth_disease
Medical condition
ulnar neuropathy at the elbow is a condition where pressure on the ulnar nerve as it passes through the cubital tunnel causes ulnar neuropathy. The symptoms
Ulnar_neuropathy_at_the_elbow
Medical condition
astasis. A combination of weakness of the triceps surae muscle, peripheral neuropathy, and irregular postural movements are the leading theories thus
Astasis
Class of vitamins
and eyes, plus neurological effects that include drowsiness and peripheral neuropathy affecting sensory and motor nerves in the hands and feet. In addition
Vitamin_B6
Immunomodulatory drug
Severe side effects include tumor lysis syndrome, blood clots, and peripheral neuropathy. Thalidomide is a known human teratogen and carries an extremely
Thalidomide
Symptoms resulting from chronic, direct pressure on a peripheral nerve
or compression neuropathy, or nerve entrapment syndrome, is a medical condition caused by chronic, direct pressure on a peripheral nerve. It is known
Nerve_compression_syndrome
Microtubules in nervous tissue neurons
13 protofilament structure of neurotubule. Chemotherapy-induced peripheral neuropathy is a pathological change in neurons caused by the disruption in
Neurotubule
Scientific discipline
variety of neurological problems including, myelopathy, peripheral neuropathy, and optic neuropathy. Affected individuals typically present difficulty walking
Nutritional_neuroscience
Form of vitamin B12
intravenous methylcobalamin is researched as treatment of peripheral neuropathy, diabetic neuropathy, and as a preliminary treatment for amyotrophic lateral
Methylcobalamin
Protein-coding gene in the species Homo sapiens
Gain-of-function mutations of NaV1.8, identified in patients with painful peripheral neuropathies, have been found to make DRG neurons hyper excitable, and thus
Nav1.8
Pharmaceutical compound
B supplement. Metanx is indicated for the dietary management of peripheral neuropathy (i.e. DPN). Metanx contains the following active ingredients (per
Metanx
Antibody-drug conjugate
The most common adverse reactions include peripheral neuropathy, fatigue, decreased appetite, and peripheral edema. The most common grade 3 or 4 laboratory
Telisotuzumab_vedotin
Peripheral nervous system disorder
Femoral nerve dysfunction, also known as femoral neuropathy, is a rare type of peripheral nervous system disorder that arises from damage to nerves, specifically
Femoral_nerve_dysfunction
Metabolic disease involving abnormal deposited amyloid proteins
system involvement, along with peripheral involvement which causes sensory and autonomic neuropathies. Sensory neuropathy develops in a symmetrical pattern
Amyloidosis
Inflammation due to periodic blood vessel blockage
condition). Secondary erythromelalgia can result from small fiber peripheral neuropathy of any cause, polycythemia vera, essential thrombocythemia, hypercholesterolemia
Erythromelalgia
Cancer of plasma cells
compression) or carpal tunnel syndrome, and other neuropathies (due to infiltration of peripheral nerves by amyloid) may occur. It may give rise to paraplegia
Multiple_myeloma
Antibiotic for treatment of tuberculosis
treated with isoniazid include vitamin B6 deficiency, liver toxicity, peripheral neuropathy, and a reduction in blood cell production. Mutations in the ahpC
Isoniazid
Medical condition
sensory and autonomic neuropathies – all characterized by progressive loss of function that predominantly affects the peripheral sensory nerves. Their
Hereditary sensory and autonomic neuropathy
Hereditary_sensory_and_autonomic_neuropathy
Dermal sensation with no physical cause
neurological disorder. Neuropathy is also a side effect of some chemotherapies, such as in the case of chemotherapy-induced peripheral neuropathy. Chronic paresthesia
Paresthesia
Medical condition
Vasculitic neuropathy is a peripheral neuropathic disease. In a vasculitic neuropathy there is damage to the vessels that supply blood to the nerves. It
Vasculitic_neuropathy
Abnormal formation of clumps of inflammatory cells (granulomata)
hypothalamic and pituitary abnormalities, chronic meningitis, and peripheral neuropathy. Myelopathy, that is spinal cord involvement, occurs in about 16–43%
Sarcoidosis
Human male external reproductive organ
lowers the likelihood of permanent penile curvature. In diabetes, peripheral neuropathy can cause tingling in the penile skin and possibly reduced or completely
Human_penis
Chemical compound; chemotherapy medication
vincristine are chemotherapy-induced peripheral neuropathy, hyponatremia, constipation, and hair loss. Vincristine-induced neuropathy is the main dose-limiting side
Vincristine
Group of endocrine diseases characterized by high blood sugar levels
stage kidney disease requiring kidney transplantation. Diabetic peripheral neuropathy (DPN) affects 30% of all diabetes patients. When DPN is superimposed
Diabetes
Method of measuring skin conductance
and assess sudomotor (or sweat gland) function and small fiber peripheral neuropathy. The measure was principally developed by Impeto Medical to diagnose
Electrochemical skin conductance
Electrochemical_skin_conductance
disorders A neuropathy affects the peripheral nerves. Guillain–Barré syndrome Charcot–Marie–Tooth disease Chemotherapy-induced peripheral neuropathy Median
List of neuromuscular disorders
List_of_neuromuscular_disorders
Medical condition
fibril formation. The aggregation of one precursor protein leads to peripheral neuropathy and/or autonomic nervous system dysfunction. These proteins include:
Familial_amyloid_neuropathy
Form of L-carnitine
Peripheral neuropathy: Meta-analyses from 2015 and 2017 both conclude that the current evidence suggests ALC reduces pain from peripheral neuropathy with
Acetylcarnitine
Autoimmune disease
vaccines were still positive. COVID-19 has been reported as causing peripheral neuropathy and more recently some evidence of aggravation of autoimmune disorders
Guillain–Barré_syndrome
Chemical herbicide and defoliant
lymphoma, soft tissue sarcoma, chloracne, porphyria cutanea tarda, peripheral neuropathy, chronic lymphocytic leukemia, and spina bifida in children of veterans
Agent_Orange
Infectious disease caused by Borrelia bacteria, spread by ticks
may form and rupture. In early US studies of Lyme disease, a rare peripheral neuropathy was described that included numbness, tingling, or burning starting
Lyme_disease
Medical condition
diagnosed clinically. It should be connected to peripheral artery disease and peripheral neuropathy with underlying artery manipulation. Electro-diagnostic
Ischemic_monomelic_neuropathy
Drug for chronic pain
China, it was approved in May 2024 for the treatment of diabetic peripheral neuropathy with neuropathic pain and approved in July 2024 for the treatment
Crisugabalin
Medication
The most common adverse reactions include dizziness, dysgeusia, peripheral neuropathy, constipation, dyspnea, ataxia, fatigue, cognitive disorders, and
Repotrectinib
Nerve that carries sensory information toward the central nervous system
Dictionary Peripheral Neuropathy from the US NIH Neuropathy: Causes, Symptoms and Treatments from Medical News Today Peripheral Neuropathy at the Mayo
Sensory_nerve
Irish neurologist
at National Hospital for Neurology and Neurosurgery. She studies peripheral neuropathy. She is the President of the Association of British Neurologists
Mary_Reilly_(academic)
Speed at which an electrochemical impulse propagates down a neural pathway
various medical conditions. Studies allow for better diagnoses of various neuropathies, especially demyelinating diseases as these conditions result in reduced
Nerve_conduction_velocity
Medical disorders that destroy blood vessels by inflammation
Examples of this type of vasculitis include gastrointestinal, cutaneous, and peripheral nerve vasculitides. Laboratory tests of blood or body fluids are performed
Vasculitis
Compression of the median nerve in the wrist
characteristic of compressive median neuropathy at the carpal tunnel of the wrist. Compressive median neuropathy is a structural, largely hereditary condition
Carpal_tunnel_syndrome
Chronic multi-symptomatic pain disorder
(e.g., rheumatic illnesses) and neuropathic (e.g., small fiber peripheral neuropathy) pain in addition to nociplastic pain. Fibromyalgia can be viewed
Fibromyalgia
Canadian comedian (1959–2021)
him to gain weight. After chemotherapy, Macdonald suffered from peripheral neuropathy, which led him to give up golf and tennis. The cancer went into
Norm_Macdonald
American neurologist
neurological disorders, with an emphasis on ALS and neuropathy. Feldman served as President of the Peripheral Nerve Society from 2007 to 2009. She was also
Eva_Feldman
Medical condition
Hereditary sensory and autonomic neuropathy type I (HSAN I) or hereditary sensory neuropathy type I (HSN I) is a group of autosomal dominant inherited
Hereditary sensory and autonomic neuropathy type I
Hereditary_sensory_and_autonomic_neuropathy_type_I
Medical condition
manifestations (palpable purpura and livedo racemosa), seizures or peripheral neuropathy, abdominal pain. The kidneys are affected in up to 80% of cases
Microscopic_polyangiitis
Cast designed to take weight of the foot
walking) Peripheral neuropathy (damage to the nerves in the feet). These factors rarely cause problems in healthy people but the accompanying neuropathy means
Total_contact_casting
Chemical compound
advanced HIV-1 disease, a history of peripheral neuropathy, or individuals on other drugs that have association with neuropathy develop this side effect more
Stavudine
Fatty substance insulating nerve cell axons
disease, multiple sclerosis; and the inflammatory demyelinating peripheral neuropathies. Due to its high prevalence, multiple sclerosis, which specifically
Myelin
Mitochondrial disorder
Secondary features include dementia, optic atrophy, bilateral deafness, peripheral neuropathy, spasticity, or multiple lipomata. Mitochondrial disorders, including
MERRF_syndrome
Medical condition
Diabetes Association. Retrieved 14 November 2025. Said, Gérard (2014). Peripheral Neuropathy & Neuropathic Pain. Place of publication not identified: TFM Publishing
Proximal_diabetic_neuropathy
Medical condition
folate deficiency, magnesium deficiency, sleep apnea, diabetes, peripheral neuropathy, Parkinson's disease, and certain autoimmune diseases, such as multiple
Restless_legs_syndrome
Medical condition
evaluation for a wide variety of clinical symptoms and disorders (e.g., peripheral neuropathy, vasculitis, hemolytic anemia, skin rashes, hypercalcemia, or elevated
Monoclonal gammopathy of undetermined significance
Monoclonal_gammopathy_of_undetermined_significance
Chemical compound (C6H14)
levels of n-hexane has been demonstrated to be associated with peripheral neuropathy in auto mechanics in the US, and neurotoxicity in workers in printing
Hexane
Medical condition
dorsal ganglionic neurons with degeneration of their peripheral and central axons (peripheral neuropathy and posterior column degeneration respectively).
Subacute combined degeneration of spinal cord
Subacute_combined_degeneration_of_spinal_cord
Diagnostic test for nerve function
Guyon's canal syndrome Peripheral neuropathy Peroneal neuropathy Spinal disc herniation Tarsal Tunnel Syndrome Ulnar neuropathy Motor NCS are obtained
Nerve_conduction_study
Injury to the innermost layer of the aorta
congestive heart failure (7%), fainting (9%), stroke (6%), ischemic peripheral neuropathy, paraplegia, and cardiac arrest. If the individual fainted, about
Aortic_dissection
Medical condition
syndrome Adams-Oliver syndrome 2 Agenesis of the corpus callosum with peripheral neuropathy ALG11-congenital disorder of glycosylation Barber-Say syndrome Blepharophimosis
Low_anterior_hairline
Ability to perceive vibration
mellitus. The peripheral nervous system is composed of afferent and efferent neurons; disorder of these neurons is called peripheral neuropathy. Vibration
Pallesthesia
Medical condition
involuntary motor tics, or peripheral neuropathy (damage to the nerves outside of the brain and spinal cord). Peripheral neuropathy causes loss of sensation
Abetalipoproteinemia
and cyclizine. Vincristine sometimes causes chemotherapy-induced peripheral neuropathy, a progressive and persistent condition involving tingling numbness
Hyper-CVAD
Discomfort in the legs during walking due to nerve impingement
Muscle pain Vertebral compression fracture Compartment syndrome Peripheral neuropathy Both neurogenic claudication and vascular claudication manifest
Neurogenic_claudication
Autoimmune disorder
the disease. Some of these more uncommon manifestations include peripheral neuropathy, epilepsy, psoriasis, recurrent aphthous stomatitis, pericardial
Coeliac_disease
Statin medication
other signs of infection numbness or tingling in fingers or toes (peripheral neuropathy) Allergic reactions can develop: rash hives itching difficulty breathing
Rosuvastatin
Medication
(MMAE) and the linker. The most common side effects include fatigue, peripheral neuropathy (nerve damage resulting in tingling or numbness), decreased appetite
Enfortumab_vedotin
Any disorder of the nervous system
Dysarthria (speech) Spinal cord disorders Peripheral nervous system disorders (e.g., Peripheral neuropathy) Cranial nerve disorder (e.g., trigeminal neuralgia)
Neurological_disorder
Excess urea in the blood due to kidney dysfunction
taste and smell, hiccups, serositis Peripheral nervous system polyneuritis, restless legs, cramps, peripheral neuropathy, oxidative stress, reduced body temperature
Uremia
Group of visual disorders
of a genuine optic neuropathy, sometimes associated with involvement of the peripheral nervous system, called peripheral neuropathy. Loss of vision is
Mitochondrial optic neuropathies
Mitochondrial_optic_neuropathies
Anatomical system consisting of the kidneys, ureters, urinary bladder, and the urethra
Medicine. 161 (4): 311–8. doi:10.1620/tjem.161.311. PMID 2256104. "Peripheral Neuropathy". Patient UK. Retrieved 2014-03-20. Balk, Ethan; Adam, Gaelen P
Urinary_system
Highly focused interests in autistic people
complex developmental disorder Neurodiversity Neuroqueer theory Peripheral neuropathy Reduced affect display Sanism Self-harm Suicidal ideation TEACCH
Special_interest_(autism)
Painful sensations in muscle tissue
syndrome Hypokalemia Hypotonia Exercise intolerance Mastocytosis Peripheral neuropathy Eosinophilia myalgia syndrome Barcoo fever Herpes Hemochromatosis
Myalgia
An epidemic of optic and peripheral neuropathy occurred in Cuba during 1991–1994. According to a preliminary summary from the Ministry of Public Health
Cuban_neuropathy
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