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Database of protein families, domains and functional sites
InterPro is a database of protein families, protein domains and functional sites in which identifiable features found in known proteins can be applied
InterPro
1991–92; four Interpro and four representative starts in 1992-23; four Interpro and three representative starts in 1993–94; four interpro and four representative
List of Ulster Rugby players of the professional era
List_of_Ulster_Rugby_players_of_the_professional_era
Cycling team
Interpro Cycling Academy is a Japanese UCI Continental cycling team founded in 2017. By the end of 2019 season, the team was merged to Hincapie–Leomo p/b
Interpro_Cycling_Academy
Protease commonly found in natto
Bacillus subtilis natto Symbol aprN Orthologs OMA: entry UniProt P35835 Other data EC number 3.4.21.62 Search for Structures Swiss-model Domains InterPro
Nattokinase
Electron transfer protein
Phormidium laminosum plastocyanin, PDB: 3BQV. Identifiers Symbol Plastocyanin InterPro IPR002387 CATH 3BQV SCOP2 3BQV / SCOPe / SUPFAM CDD cd04219 Available protein
Plastocyanin
Iron-carrying protein
ferritin complex Identifiers Symbol Ferritin Pfam PF00210 Pfam clan CL0044 InterPro IPR008331 SCOP2 1fha / SCOPe / SUPFAM Available protein structures: PDB
Ferritin
Protein family
other domains such as UBA (INTERPRO), UBX (INTERPRO), ENTH domain, EH (INTERPRO), VHS (INTERPRO), SH3 domain, HECT, VWFA (INTERPRO), EF-hand calcium-binding
Ubiquitin-interacting_motif
Family of DNA sequences found in prokaryotic organisms
CRISPR Entrez 947229 Orthologs NCBI: entry; OMA: entry PDB 4QYZ RefSeq (Prot) NP_417241.1 UniProt P38036 Search for Structures Swiss-model Domains InterPro
CRISPR
Protein family
GTP hydrolysis by the α-subunit (InterPro: IPR001019), which can then re-bind the βγ-dimer (InterPro: IPR001632 InterPro: IPR001770) and the receptor. RGS
Regulator of G protein signaling
Regulator_of_G_protein_signaling
Serum albumin protein derived from cows
RefSeq (mRNA) NM_180992 RefSeq (Prot) NP_851335 UniProt P02769 Other data Chromosome 6: 91.54 - 91.57 Mb Search for Structures Swiss-model Domains InterPro
Bovine_serum_albumin
Class of enzymes
entry PDB 4CMS UniProt P00794 Search for Structures Swiss-model Domains InterPro chymosin pseudogene (human) Identifiers Symbol CYMP NCBI gene 643160 HGNC
Chymosin
Class of enzymes
number 1.2.4.1 Locus Chr. X p22.1 Search for Structures Swiss-model Domains InterPro pyruvate dehydrogenase (lipoamide) alpha 2 Identifiers Symbol PDHA2 Alt
Pyruvate_dehydrogenase
Enzyme that synthesizes RNA from an RNA template
viruses with non-segmented genomes; InterPro: IPR016269) Negative-strand RNA viruses with segmented genomes (InterPro: IPR007099), such as orthomyxoviruses
RNA-dependent_RNA_polymerase
Species of fish
protein UnaG Identifiers Organism Anguilla japonica Symbol UnaG Orthologs OMA: entry UniProt P0DM59 Search for Structures Swiss-model Domains InterPro
Japanese_eel
Class of enzymes
HK1 NCBI gene 3098 HGNC 4922 OMIM 142600 RefSeq NM_000188 UniProt P19367 Other data Locus Chr. 10 q22 Search for Structures Swiss-model Domains InterPro
Hexokinase
Family of digestive enzymes
Trypsin Identifiers Symbol Trypsin Pfam PF00089 InterPro IPR001254 SMART SM00020 PROSITE PDOC00124 MEROPS S1 SCOP2 1c2g / SCOPe / SUPFAM CDD cd00190 Available
Trypsin
Insect protein
Organism Drosophila melanogaster Symbol resilin Alt. symbols CG15920 Orthologs OMA: entry UniProt Q9V7U0 Search for Structures Swiss-model Domains InterPro
Resilin
Family of proteins
CXC1) InterPro: IPR005393 chemokine (C-X3-C motif) receptor 1 (CX3CR1, C3X1) InterPro: IPR005387 GPR137B (GPR137B, TM7SF1) Chemokine receptor InterPro: IPR000355
Rhodopsin-like_receptors
Protein that exhibits bright green fluorescence when exposed to ultraviolet light
fluorescent protein. Identifiers Symbol GFP Pfam PF01353 Pfam clan CL0069 InterPro IPR011584 CATH 1ema SCOP2 1ema / SCOPe / SUPFAM Available protein structures:
Green_fluorescent_protein
Type of transcription factor
composed of: a non-DNA-binding CBFβ chain (InterPro: IPR003417) Human: CBFB a DNA-binding CBFα chain (InterPro: IPR016554) Human: RUNX1, RUNX2, RUNX3 de
Core_binding_factor
Digestive enzyme
3.4.21.1 Locus Chr. 16 q23.1 Search for Structures Swiss-model Domains InterPro Chymotrypsinogen B2 Identifiers Symbol CTRB2 NCBI gene 440387 HGNC 2522
Chymotrypsin
Enzyme expressed mainly in the thyroid gland
12015 OMIM 606765 RefSeq NM_175722 UniProt P07202 Other data EC number 1.11.1.8 Locus Chr. 2 pter-p24 Search for Structures Swiss-model Domains InterPro
Thyroid_peroxidase
Peptide hormone that stimulates growth
NCBI gene 98 HGNC 4261 OMIM 139250 RefSeq NM_022562 UniProt P01241 Other data Locus Chr. 17 q22-q24 Search for Structures Swiss-model Domains InterPro
Growth_hormone
Peptide:N-glycosidase F Identifiers Symbol PNGase F PDB 1PGS UniProt Q9XBM8 Search for Structures Swiss-model Domains InterPro
PNGase_F
Class of enzymes
NCBI gene 8694 HGNC 2843 OMIM 604900 RefSeq NM_012079 UniProt O75907 Other data Locus Chr. 8 q24.3 Search for Structures Swiss-model Domains InterPro
Diglyceride_acyltransferase
Genetic disorder
Other data Locus Chr. 9 q34 Search for Structures Swiss-model Domains InterPro Tuberin Identifiers Symbol TSC2 NCBI gene 7249 HGNC 12363 OMIM 191092 RefSeq
Tuberous_sclerosis
Superfamily of oxygen-transporting globular proteins
InterPro: IPR001032 Myoglobin InterPro: IPR002335 Erythrocruorin InterPro: IPR002336 Hemoglobin, beta InterPro: IPR002337 Hemoglobin, alpha InterPro: IPR002338
Globin
Low-calorie sweetener and flavor modifier
hdl:2433/175269. PMID 23370115. Chang HY (31 March 2015). "The Sweetest Thing". InterPro Protein Focus. Higginbotham JD (1986). Gelardi RC, Nabors LO (eds.). Alternative
Thaumatin
Protein family
distending toxin Identifiers Symbol CDT Pfam PF03498 Pfam clan CL0066 InterPro IPR003558 Available protein structures: PDB IPR003558 PF03498 (ECOD;
Cytolethal_distending_toxin
Protein domain
low-density lipoprotein receptor. Identifiers Symbol Ldl_recept_a Pfam PF00057 InterPro IPR002172 SMART SM00192 PROSITE PS50068 SCOP2 1ldl / SCOPe / SUPFAM Membranome
Low-density lipoprotein receptor gene family
Low-density_lipoprotein_receptor_gene_family
Class of proteins
Penicillin-binding protein, transpeptidase Identifiers Symbol PCN-bd_Tpept Pfam PF00905 InterPro IPR001460 OPM superfamily 195 OPM protein 5hlb Membranome 541 Available
Penicillin-binding_proteins
Enzyme involved in metabolic pathways
HGNC 11834 OMIM 606781 RefSeq NM_001064 UniProt P29401 Other data EC number 2.2.1.1 Locus Chr. 3 p14.3 Search for Structures Swiss-model Domains InterPro
Transketolase
Protein domain found in carbohydrate-active enzymes
from the public domain Pfam and InterPro: IPR000254 This article incorporates text from the public domain Pfam and InterPro: IPR002883 This article incorporates
Carbohydrate-binding_module
Hormone for the maternal recognition of pregnancy
NCBI gene 1081 HGNC 1885 OMIM 118850 RefSeq NM_000735 UniProt P01215 Other data Locus Chr. 6 q14-q21 Search for Structures Swiss-model Domains InterPro
Human_chorionic_gonadotropin
transferase Mcr-1 Identifiers Organism Escherichia coli Symbol mcr1 Orthologs OMA: entry UniProt A0A0R6L508 Search for Structures Swiss-model Domains InterPro
MCR-1
Protein
Scramblase Identifiers Symbol Scramblase Pfam PF03803 Pfam clan CL0395 InterPro IPR005552 Membranome 231 Available protein structures: PDB IPR005552
Phospholipid_scramblase
Embryonic signaling pathway for proper cell differentiation
hedgehog Identifiers Organism Drosophila melanogaster Symbol hh Orthologs OMA: entry UniProt Q02936 Search for Structures Swiss-model Domains InterPro
Hedgehog_signaling_pathway
Group of peptides
an aqueous environment (pdb 2lfm) Identifiers Symbol APP Pfam PF03494 InterPro IPR013803 SCOP2 2lfm / SCOPe / SUPFAM TCDB 1.C.50 OPM superfamily 304 OPM
Amyloid_beta
Group of protein isoforms involved in enamel development
NCBI gene 265 HGNC 461 OMIM 300391 RefSeq NM_001142 UniProt Q99217 Other data Locus Chr. X p22.3-p22.1 Search for Structures Swiss-model Domains InterPro
Amelogenin
Integrin complex found on platelets
NCBI gene 3674 HGNC 6138 OMIM 607759 RefSeq NM_000419 UniProt P08514 Other data Locus Chr. 17 q21.32 Search for Structures Swiss-model Domains InterPro
Glycoprotein_IIb/IIIa
Protein family
gene 8900 HGNC 1577 OMIM 604036 RefSeq NM_003914 UniProt P78396 Other data Locus Chr. 13 q12.3-q13 Search for Structures Swiss-model Domains InterPro
Cyclin_A
Database of protein families
June 2024 and contains 21,979 families. It is currently provided through InterPro website. The general purpose of the Pfam database is to provide a complete
Pfam
Class of enzymes
PDB: [3] PDB: [4] Identifiers Symbol UGGT UniProt G0SB58 Other data Locus Chr. 2 {{{Arm}}}{{{Band}}} Search for Structures Swiss-model Domains InterPro
UGGT
Class of enzymes
HGNC 11177 OMIM 102642 RefSeq NM_003101 UniProt P35610 Other data EC number 2.3.1.26 Locus Chr. 1 q25 Search for Structures Swiss-model Domains InterPro
Sterol_O-acyltransferase
Protein family
incorporates text from the public domain Pfam and InterPro: IPR002210 This article incorporates text from the public domain Pfam and InterPro: IPR000784
Late_protein
Hexameric enzyme
1.3 Locus Chr. 10 q21.1-24.3 Search for Structures Swiss-model Domains InterPro glutamate dehydrogenase 2 Identifiers Symbol GLUD2 Alt. symbols GLUDP1
Glutamate_dehydrogenase
Gene of insects
Doublesex Identifiers Organism Drosophila melanogaster Symbol dsx Orthologs OMA: entry UniProt P23023 Search for Structures Swiss-model Domains InterPro
Doublesex
InterPro Family
InterPro Family
4-hydroxy-tetrahydrodipicolinate reductase
4-hydroxy-tetrahydrodipicolinate_reductase
Protein family
gene 1528 HGNC 2570 OMIM 250790 PDB 1JEX RefSeq NM_001914 UniProt P00167 Other data Locus Chr. 18 q23 Search for Structures Swiss-model Domains InterPro
Cytochrome_b5
Indian actor, director and screenwriter
Consultant – at ProLease India Pvt. Ltd., part of the Washington DC–based Interpro Group.[citation needed] Currently, he heads the Consulting and Training
Kitty_(actor)
Protein
Identifiers Organism Dioscoreophyllum cumminsii Symbol MonB Orthologs OMA: entry PDB 2O9U UniProt P02882 Search for Structures Swiss-model Domains InterPro
Monellin
Family of proteins which produce bioluminescence
from the public domain Pfam and InterPro: IPR018804 This article incorporates text from the public domain Pfam and InterPro: IPR007959 This article incorporates
Luciferase
Biological database
Conserved Domain Database collection and is also distributed as part of the InterPro database. The database is hosted by the European Molecular Biology Laboratory
Simple Modular Architecture Research Tool
Simple_Modular_Architecture_Research_Tool
Immunoglobulin-binding protein expressed in group C and G Streptococcal bacteria
GA-like domain Identifiers Symbol ? Pfam PF17573 InterPro IPR035152 Available protein structures: PDB IPR035152 PF17573 (ECOD; PDBsum) AlphaFold IPR035152
Protein_G
Enzyme that hydrolyses α bonds of large α-linked polysaccharides
from the public domain Pfam and InterPro: IPR006047 This article incorporates text from the public domain Pfam and InterPro: IPR012850 This article incorporates
Α-Amylase
Chemical compound and enzyme
symbols PRXC1A Orthologs OMA: entry PDB 1W4WMore structures UniProt P00433 Other data EC number 1.11.1.7 Search for Structures Swiss-model Domains InterPro
Horseradish_peroxidase
Bacterial system for secreting proteins
III secretion system protein Identifiers Symbol Secretin Pfam PF00263 InterPro IPR004846 TCDB 3.A.5 OPM superfamily 348 OPM protein 5wln Membranome 430
Type_II_secretion_system
Enzyme from bacteriophage ϕ29
DNA polymerase Identifiers Organism Bacillus phage phi29 Symbol 2 Orthologs OMA: entry UniProt P03680 Search for Structures Swiss-model Domains InterPro
Φ29_DNA_polymerase
Class of enzymes
HGNC 8091 OMIM 258870 RefSeq NM_000274 UniProt P04181 Other data EC number 2.6.1.13 Locus Chr. 10 q26 Search for Structures Swiss-model Domains InterPro
Ornithine_aminotransferase
Group of transport proteins
NCBI gene 6523 HGNC 11036 OMIM 182380 RefSeq NM_000343 UniProt P13866 Other data Locus Chr. 22 q13.1 Search for Structures Swiss-model Domains InterPro
Sodium-glucose transport proteins
Sodium-glucose_transport_proteins
Class of enzymes
(component 1 subunit alpha/beta) Identifiers Symbol Oxidored_nitro Pfam PF00148 InterPro IPR000510 SCOP2 1mio / SCOPe / SUPFAM Available protein structures: PDB
Nitrogenase
Site-directed recombination technology
recombinase Flp Identifiers Organism Saccharomyces cerevisiae Symbol FLP1 Orthologs OMA: entry UniProt P03870 Search for Structures Swiss-model Domains InterPro
FLP-FRT_recombination
Protein family
from the public domain Pfam and InterPro: IPR022217 This article incorporates text from the public domain Pfam and InterPro: IPR019506 This article incorporates
Protease_inhibitor_(biology)
Family of toxins produced by spiders
Mol. Biol. 297 (3): 771–780. doi:10.1006/jmbi.2000.3609. PMID 10731427. InterPro: IPR013140 Kim JI, Konishi S, Iwai H, Kohno T, Gouda H, Shimada I, Sato
Spider_toxin
Gonadotropin secreted by the adenohypophysis
NCBI gene 1081 HGNC 1885 OMIM 118850 RefSeq NM_000735 UniProt P01215 Other data Locus Chr. 6 q14-q21 Search for Structures Swiss-model Domains InterPro
Luteinizing_hormone
Human blood group system
OMIM 111730 RefSeq NP_001152859.1 UniProt Q8NHY0 Other data EC number 2.4.1.165 Locus Chr. 17 q21.32 Search for Structures Swiss-model Domains InterPro
Sid_blood_group_system
Group of transposable elements
4029 HGNC 6686 OMIM 151626 PDB 2LDY UniProt Q9UN81 Other data Locus Chr. 22 q12.1 Wikidata Q18028646 Search for Structures Swiss-model Domains InterPro
LINE1
InterPro Family
of DnaK, resolved at 2.8 angstrom. Identifiers Symbol GrpE Pfam PF01025 InterPro IPR000740 PROSITE PS01071 SCOP2 1dkg / SCOPe / SUPFAM CDD cd00446 Available
GrpE
Protein family
Glycolipid transfer protein (GLTP) Identifiers Symbol GLTP Pfam PF08718 InterPro IPR014830 OPM superfamily 84 OPM protein 1swx Available protein structures:
Glycolipid_transfer_protein
Protein domain
from the public domain Pfam and InterPro: IPR007693 This article incorporates text from the public domain Pfam and InterPro: IPR007694 Portal: Biology
DnaB_helicase
Annual hurling competition season
24 October 2005. Retrieved 15 July 2025. "Munster to face Leinster in Interpro final in Boston". Irish Examiner. 23 October 2005. Retrieved 15 July 2025
2006 Wexford Senior Hurling Championship
2006_Wexford_Senior_Hurling_Championship
Glycoprotein polypeptide hormones
Glycoprotein hormone Identifiers Symbol Hormone_6 Pfam PF00236 InterPro IPR000476 PROSITE PDOC00623 SCOP2 1hcn / SCOPe / SUPFAM Available protein structures:
Gonadotropin
Family of proteins
purple. (PDB: 2KAK) Identifiers Symbol Metallothionein_sfam Pfam PF00131 InterPro IPR003019 Available protein structures: PDB PDB: 1dfs PDB: 1dft PDB:
Metallothionein
Protein-coding gene in the species Homo sapiens
(mRNA) NM_057598 RefSeq (Prot) NP_476946 UniProt Q24118 Other data Chromosome 2L: 19.19 - 19.19 Mb Search for Structures Swiss-model Domains InterPro
Gamma-secretase-activating protein
Gamma-secretase-activating_protein
Class of enzymes
Phosphofructokinase Identifiers Symbol PFK Pfam PF00365 Pfam clan CL0240 InterPro IPR000023 PROSITE PDOC00336 SCOP2 5pfk / SCOPe / SUPFAM Available protein
Phosphofructokinase_1
Protein-coding gene in the species Homo sapiens
with bound pcmbs Identifiers Symbol TAFII28 Pfam PF04719 Pfam clan CL0012 InterPro IPR006809 SCOP2 1bh9 / SCOPe / SUPFAM Available protein structures: PDB
TAF11
Family of enzyme complexes
RefSeq (Prot) NP_418482.1 UniProt P0A698 Other data EC number 3.6.1.3 Chromosome genomic: 4.27 - 4.27 Mb Search for Structures Swiss-model Domains InterPro
UvrABC_endonuclease
Class of enzyme
apo form Identifiers Symbol Alliinase_C Pfam PF04864 Pfam clan CL0061 InterPro IPR006948 SCOP2 1lk9 / SCOPe / SUPFAM Available protein structures: PDB
Alliinase
Blood proteins made in the liver and secreted into the bloodstream
Other data Locus Chr. 3 q27.3 Search for Structures Swiss-model Domains InterPro fetuin-B Identifiers Symbol FETUB Alt. symbols 16G2, Gugu NCBI gene 26998
Fetuin
Class of enzymes
OMIM 607633 PDB 1FIQ RefSeq NM_000379 UniProt P47989 Other data EC number 1.17.3.2 Locus Chr. 2 p23.1 Search for Structures Swiss-model Domains InterPro
Xanthine_oxidase
Enzyme which generates DNA
nuclease highlighted Identifiers Symbol RVT_1 Pfam PF00078 Pfam clan CL0027 InterPro IPR000477 PROSITE PS50878 SCOP2 1hmv / SCOPe / SUPFAM CDD cd00304 Available
Reverse_transcriptase
Former Rugby Union competition in Ireland
Football Union. The Interprovincial Championship, often shortened to the Interpros, was run as a distinct competition from 1946–47 to 2000–01, with the 2001–02
IRFU Interprovincial Championship
IRFU_Interprovincial_Championship
Enzyme
biosynthesis pathway) consists of three subunits, CobT, CobN (InterPro: IPR003672) and CobS (InterPro: IPR006537). The macrocycle of vitamin B12 can be complexed
Cobalt_chelatase
Type of lectin
(Prot) XP_002534649.1 UniProt P02879 Other data EC number 3.2.2.22 Chromosome whole genome: 0 - 0.01 Mb Search for Structures Swiss-model Domains InterPro
Ricin
Toxic lectin
(PDB 1fat) Identifiers Symbol Lectin_legB Pfam PF00139 Pfam clan CL0004 InterPro IPR001220 PROSITE PDOC00278 SCOP2 1lem / SCOPe / SUPFAM Available protein
Phytohaemagglutinin
Protein family
2017.03.002 |http://www.insect.org.cn/EN/10.16380/j.kcxb.2017.03.002 This article incorporates text from the public domain Pfam and InterPro: IPR010009
Apolipophorin_III
Library of Medicine Medical Subject Headings (MeSH) Portal: Biology This article incorporates text from the public domain Pfam and InterPro: IPR015409
D-lactate_dehydrogenase
Spanish cyclist
"Pablo Torres encuentra hueco en el Interpro Cycling Academy japonés" [Pablo Torres finds a gap in the Japanese Interpro Cycling Academy]. Ciclismo a Fondo
Pablo Torres (cyclist, born 1987)
Pablo_Torres_(cyclist,_born_1987)
win first Interpro crown". www.irishexaminer.com. 26 November 2005. Retrieved 24 July 2018. "Women's: Leinster End Munster's Grip On Interpro Title". www
2025–26_Connacht_Rugby_season
Protein family
P24 protein family Identifiers Symbol TMP21 Pfam PF01105 InterPro IPR015720 Membranome 140 Available protein structures: PDB IPR015720 PF01105 (ECOD;
P24_protein_family
Protein-coding gene in Drosophila melanogaster
(Prot) NP_001263132.1 UniProt O76324 Other data EC number 2.7.11.1 Chromosome 3R: 26.88 - 26.89 Mb Search for Structures Swiss-model Domains InterPro
Doubletime_(gene)
Family of globular proteins
albumin This article incorporates text from the public domain Pfam and InterPro: IPR014760 Sugio S, Kashima A, Mochizuki S, Noda M, Kobayashi K (June 1999)
Albumin
Rugby team
Guinness Pro12, retrieved 29 August 2026 Tony Ward, "Fitness guru kicks Interpro games to touch", Irish Independent, 18 December 2001 Aidan Corr, "Munster
2001–02_Leinster_Rugby_season
Symbol N/A Orthologs OMA: entry PDB 2NN3 RefSeq (mRNA) U81510.1 RefSeq (Prot) AAC47442.1 UniProt P89116 Search for Structures Swiss-model Domains InterPro
Sf_caspase-1
Protein family
Identifiers Symbol NuA4 Pfam PF09340 InterPro IPR015418 Available protein structures: PDB PDB: 8esc 1myu 1n6t IPR015418 PF09340 (ECOD; PDBsum) AlphaFold
NuA4 histone acetyltransferase complex
NuA4_histone_acetyltransferase_complex
RefSeq (Prot) NP_414751.1 UniProt P03007 Other data EC number 2.7.7.7 Chromosome genome: 0.24 - 0.24 Mb Search for Structures Swiss-model Domains InterPro
DnaQ
Protein family
from the public domain Pfam and InterPro: IPR000036 This article incorporates text from the public domain Pfam and InterPro: IPR012848 Portal: Biology
Aspartic_protease
Family of transmembrane proteins
the European Bioinformatics Institute Identifiers Symbol Bac_rhodopsin InterPro CD15243 SCOP2 8071317 / SCOPe / SUPFAM TCDB 3.E.1.2.2 OPM superfamily 6
Halorhodopsin
Lectin (carbohydrate-binding protein)
Identifiers Organism Canavalia ensiformis (jackbean) Symbol ConA Orthologs OMA: entry PDB 3CNA UniProt P81461 Search for Structures Swiss-model Domains InterPro
Concanavalin_A
Enzyme
number 3.4.23.1 Locus Chr. 11 q13 Search for Structures Swiss-model Domains InterPro pepsinogen 4, group I (pepsinogen A) Identifiers Symbol PGA4 NCBI gene
Pepsin
travel, tourism, insurance
INTERPRO
INTERPRO
INTERPRO
INTERPRO
INTERPRO
INTERPRO
INTERPRO
INTERPRO
INTERPRO
travel, tourism, insurance