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Chimeric RNA
Fusion transcript is a chimeric RNA encoded by a fusion gene or by two different genes by subsequent trans-splicing. Certain fusion transcripts are commonly
Fusion_transcript
Aspect of genetics
Chimeric RNA, sometimes referred to as a fusion transcript, is composed of exons from two or more different genes that have the potential to encode novel
Chimeric_RNA
2002 video game
Metroid Fusion is a 2002 action-adventure game developed and published by Nintendo for the Game Boy Advance. It is the fourth main Metroid game. Players
Metroid_Fusion
Maturation process joining exons from different pre-mRNAs into a mature mRNA
some fusion transcripts occur via trans-splicing in normal human cells, trans-splicing can also be the mechanism behind certain oncogenic fusion transcripts
Trans-splicing
Protein-coding gene in humans
Lemke I, Kazmierczak B, Bullerdiek J (2001). "An identical HMGIC-LPP fusion transcript is consistently expressed in pulmonary chondroid hamartomas with
LPP_(gene)
DNA-editing technology
Feature Cas9 Cas12a Structure Two RNA required (Or 1 fusion transcript (crRNA+tracrRNA=sgRNA) One crRNA required Cutting mechanism Blunt end cuts Staggered
Cas12a
Commercial research and strategic intelligence firm based in Washington D.C.
closed-door meeting. The Committee did not release a transcript of the hearing, but indicated that Fusion GPS had given more than 40,000 highly redacted documents
Fusion_GPS
Phenomenon that results in unusual rearrangement of an chromosomes
Debiec-Rychter, Maria (December 2012). "Recurrent and novel SS18-SSX fusion transcripts in synovial sarcoma: description of three new cases". Tumor Biology
Chromosomal_translocation
Oncogenic protein
Most fusions between EWS and FLI1 result from a t(11;22)(q24;q12) reciprocal chromosome translocation. This translocation creates a chimeric transcript which
EWS/FLI
Protein-coding gene in the species Homo sapiens
characterization of spliced fusion transcript variants of synovial sarcoma: SYT/SSX4, SYT/SSX4v, and SYT/SSX2v. Possible regulatory role of the fusion gene product in
SS18
Gene formed by the combination of two independent genes
detected gene fusions on the transcript level. Biologists may also deliberately create fusion genes for research purposes. The fusion of reporter genes
Fusion_gene
transcribed from the endogenous promoter of that gene in the form of a fusion transcript in which the exon(s) upstream of the insertion site is spliced in
Gene_trapping
Medical condition
This translocation leads to the fusion of two polycomb group genes, JAZF1 and JJAZ1, with production of a fusion transcript with anti-apoptotic properties
Endometrial_stromal_sarcoma
Lab technique in cellular biology
ability to look at alternative gene spliced transcripts, post-transcriptional modifications, gene fusion, mutations/SNPs and changes in gene expression
RNA-Seq
Multi-stage fusion-fission nuclear weapon
A thermonuclear weapon, fusion weapon, or hydrogen bomb (H-bomb) is a second-generation nuclear weapon, using nuclear fusion. The most destructive weapons
Thermonuclear_weapon
BreakDancer BreakFusion ChimeraScan EBARDenovo Easyfuse is a pipeline that combines STAR-Fusion and Fusioncatcher to detect fusion transcripts from RNA-seq
List of RNA-Seq bioinformatics tools
List_of_RNA-Seq_bioinformatics_tools
Protein-coding gene in humans
exon was transcribed. A fusion transcript containing IRF6 and the first exon of C1orf74 has also been found, but this transcript results in a short polypeptide
C1orf74
Chimeric cancer-related protein
protein Fusion gene Fusion transcript Chimeric gene Bcr-abl fusion protein Oncovirus Retrovirus Retrotransposon Retroposon Integrase gag-onc+Fusion+Proteins
Gag-onc_fusion_protein
Salivary gland neoplasm
Detection of Classical ETV6-NTRK3 Fusion Transcript by Standard RT-PCR: Report of 4 Cases Harboring ETV6-X Gene Fusion". The American Journal of Surgical
Mammary analogue secretory carcinoma
Mammary_analogue_secretory_carcinoma
Protein-coding gene in the species Homo sapiens
tissues, indicating a likely role in tissue development. MECOM and the fusion transcript MDS1-MECOM are both expressed in the adult human kidney, lung, pancreas
MECOM
Type of abnormal growth in the body
FUS and EWSR1 in its N-terminal region. TFG is also observed as a fusion transcript with ALK (2p23) in anaplastic large-cell lymphoma and with ANTRK1
Extraskeletal myxoid chondrosarcoma
Extraskeletal_myxoid_chondrosarcoma
Aggressive and rare cancer
short arm of chromosome 11. The resulting EWSR1-WT1 fusion gene is converted to a fusion transcript that directs the formation of an EWSR1-WT1 chimeric
Desmoplastic small-round-cell tumor
Desmoplastic_small-round-cell_tumor
Class of enzymes
LW, Li S, Zhau HE (2000). "Identification of a novel FAS/ER-alpha fusion transcript expressed in human cancer cells". Biochimica et Biophysica Acta (BBA)
Fatty_acid_synthase
Protein-coding gene in the species Homo sapiens
SS, Bruno A, Oh S, Schmidt ML, Lindgren V (July 2006). "MLL-SEPT6 fusion transcript with a novel sequence in an infant with acute myeloid leukemia". Cancer
SEPTIN6
Protein-coding gene in the species Homo sapiens
et al. (2007). "High incidence of CALM-AF10 fusion and the identification of a novel fusion transcript in acute megakaryoblastic leukemia in children
PICALM
Protein-coding gene in humans
[inv(16)(p13q22)] produces a chimeric transcript consisting of the N terminus of core-binding factor beta in a fusion with the C-terminal portion of the
CBFB
American technology company
Fusion-io flies too close to Facebook, Apple, plummets to Earth", The Register "Fusion-io's CEO Discusses F2Q 2014 Results - Earnings Call Transcript"
Fusion-io
Protein-coding gene in humans
breakpoints in t(8;21) acute myelogenous leukemia and isolation of a fusion transcript, AML1/ETO, with similarity to Drosophila segmentation gene, runt"
RUNX1T1
Nuclear fusion reaction
Bubble fusion is the non-technical name for a nuclear fusion reaction hypothesized to occur inside extraordinarily large collapsing gas bubbles created
Bubble_fusion
Collection of microscopic DNA spots attached to a solid surface
treatment of the data (Data analysis); mapping each probe to the mRNA transcript that it measures (Annotation); the sheer volume of data and the ability
DNA_microarray
Cell cycle protein
Vitkova P, et al. (2018). "An undifferentiated sarcoma with BCOR-CCNB3 fusion transcript - pathological and clinical retrospective study". Neoplasma. 65 (4):
Cyclin_B3
Protein-coding gene in the species Homo sapiens
Nakamura S, Nagai N, Hasegawa Y, Inagaki H (2007). "MECT1-MAML2 fusion transcript defines a favorable subset of mucoepidermoid carcinoma". Clin. Cancer
MAML2
Genetic disorder
Dobyns, William B.; Millen, Kathleen J. (July 2003). "Reciprocal fusion transcripts of two novel Zn-finger genes in a female with absence of the corpus
Weiss-Kruszka_syndrome
Protein-coding gene in the species Homo sapiens
Nakamura S, Nagai N, Hasegawa Y, Inagaki H (Jul 2006). "MECT1-MAML2 fusion transcript defines a favorable subset of mucoepidermoid carcinoma". Clinical
CRTC1
authors were able to find a fusion transcript and locate the chromosomal breakpoint in the same cell resulting in the fusion. G&T-seq also provides a strategy
G&T-seq
Paired box gene 3
genes to generate a PAX3-FOXO1 fusion gene that expresses a PAX3-FOXO1 fusion transcript encoding a PAX3-FOXO1 fusion protein. PAX3 and FOXO1 encode transcription
PAX3
Protein-coding gene in humans
JY, Wei YH, Nycum L, et al. (August 1994). "EWS-erg and EWS-Fli1 fusion transcripts in Ewing's sarcoma and primitive neuroectodermal tumors with variant
ERG_(gene)
Genetic abnormality in leukemia cancer cells
of the transcribed BCR-ABL1 fusion protein, and all encode for a tyrosine kinase protein. The e1a2 transcript is a fusion between exon 1 of BCR, also
Philadelphia_chromosome
Blood cancer characterized by overproduction of lymphoblasts
et al. (August 2008). "Simple multiplex RT-PCR for identifying common fusion transcripts in childhood acute leukemia". International Journal of Laboratory
Acute_lymphoblastic_leukemia
Malignant pediatric orbital tumor
Embryonal-type orbital tumors, which lack these fusion transcripts, are correspondingly considered fusion-negative. Ongoing molecular research into RMS
Orbital_rhabdomyosarcoma
occurring fusion between two genomic regions as in RNA-PET. RNA-PET: This application is used for studying the transcriptome: transcripts, gene structures
Paired-end_tag
Biotechnology company
"SLC45A3-ELK4 is a novel and frequent erythroblast transformation-specific fusion transcript in prostate cancer". Cancer Research. 69 (7): 2734–8. doi:10.1158/0008-5472
Dendreon
Fusion reactor design
a fusion reactor using an electric and magnetic field to heat ions to fusion conditions. The design is related to the fusor, the high beta fusion reactor
Polywell
Protein-coding gene in humans
Hsiao HH, Yang MY, Liu YC, et al. (2005). "RBM15-MKL1 (OTT-MAL) fusion transcript in an adult acute myeloid leukemia patient". Am. J. Hematol. 79 (1):
RBM15
Protein-coding gene in humans
Hsiao HP, Tseng SB, Chao MC, et al. (May 2005). "RBM15-MKL1 (OTT-MAL) fusion transcript in an adult acute myeloid leukemia patient". American Journal of Hematology
MRTFA
American physician-scientist (born 1962)
Yanding (2026-02-05). "EcDNA-borne structural variants drive oncogenic fusion transcript amplification". Cell. 189 (3): 906–921.e20. doi:10.1016/j.cell.2025
Paul_Mischel
Mammalian protein found in Homo sapiens
characterization of spliced fusion transcript variants of synovial sarcoma: SYT/SSX4, SYT/SSX4v, and SYT/SSX2v. Possible regulatory role of the fusion gene product in
SSX2
Laboratory technique used in molecular biology
unknown parts of novel transcripts and fusion transcripts in colorectal cancer. In another study aiming to characterize unknown transcript structures of lncRNAs
Rapid amplification of cDNA ends
Rapid_amplification_of_cDNA_ends
Chemical compound
breakpoints in t(8;21) acute myelogenous leukemia and isolation of a fusion transcript, AML1/ETO, with similarity to Drosophila segmentation gene, runt"
AI-10-49
Protein-coding gene in the species Homo sapiens
t(4;14)(p16;q32) translocation lacks FGFR3 expression but maintains an IGH/MMSET fusion transcript". Blood. 101 (6): 2374–6. doi:10.1182/blood-2002-09-2801. PMID 12433679
NSD2
Protein found in humans
(August 1993). "The 3;21 translocation in myelodysplasia results in a fusion transcript between the AML1 gene and the gene for EAP, a highly conserved protein
60S_ribosomal_protein_L22
Protein-coding gene in the species Homo sapiens
Dorfman HD, Raimondi SC (December 2011). "A novel EWSR1-CREB3L1 fusion transcript in a case of small cell osteosarcoma". Genes, Chromosomes & Cancer
CREB3L1
Tumor originating in adipose (fat) tissue
gene by in situ hybridization or immunohistochemistry or the RNA fusion transcripts of these genes by real-time polymerase chain reactions confirms the
Liposarcoma
Group of transposable elements
retrotransposon open reading frame-1 initiates expression of diverse fusion transcripts and limits retrotransposition". Nucleic Acids Research. 42 (7): 4546–62
LINE1
Human protein and coding gene
Mitelman F, Aman P (1995). "Characterization of the CHOP breakpoints and fusion transcripts in myxoid liposarcomas with the 12;16 translocation". Cancer Res.
RNA-binding_protein_FUS
Protein-coding gene in the species Homo sapiens
Penzel R, Sergi C, et al. (2002). "Identification of a CTL4/Neu1 fusion transcript in a sialidosis patient". FEBS Lett. 521 (1–3): 19–23. doi:10
Choline transporter-like protein 4
Choline_transporter-like_protein_4
Protein-coding gene in the species Homo sapiens
characterization of spliced fusion transcript variants of synovial sarcoma: SYT/SSX4, SYT/SSX4v, and SYT/SSX2v. Possible regulatory role of the fusion gene product in
SSX4_(gene)
Protein found in humans
gene also forms a fusion transcript with another gene called MAP3K9, that encodes for MAP3 kinase enzyme. This SLC39A9-MAP3K9 fusion gene has a repetitive
Zinc_transporter_ZIP9
Type of acute lymphoblastic leukemia
to evaluate for fusion transcripts such as SIL-TAL1. Mutation of TAL1 is frequently present in T-ALL patients, where SIL/TAL1 fusion leads to inappropriate
T-cell acute lymphoblastic leukemia
T-cell_acute_lymphoblastic_leukemia
Medical condition
suppressor gene, while sporadic cylindromas are associated with MYB-NFIB fusion transcripts. However, despite being named after the tumor, mutation in the CYLD
Cylindroma
Indian academic (born 1973)
tumours, mutually exclusive with HPV, and identified a novel UBE3C-LRP5 fusion transcript in head and neck cancer activating the Wnt/β-catenin pathway, with
Amit_Dutt
Human protein and coding gene
tumorigenicity of Ewing's sarcoma cells expressing antisense RNA to EWS-fusion transcripts". Oncogene. 11 (6): 1049–54. PMID 7566963. Ban J, Siligan C, Kreppel
RNA-binding_protein_EWS
Fictional character
(Interview: Transcript) (in Japanese). No. 56. Nintendo. Archived from the original on July 21, 2015. Retrieved February 4, 2024. "Metroid Fusion – 2003 Developer
SA-X
American journalist (born 1964)
2017. Cheney, Kyle (January 9, 2018). "Feinstein releases transcript of interview with Fusion GPS co-founder". Politico. Archived from the original on
Glenn_R._Simpson
Protein-coding gene in the species Homo sapiens
in the expression of BCL11B-TRDC fusion transcripts and is associated with the absence of wild-type BCL11B transcripts in T-ALL". Leukemia. 19 (2): 201–8
BCL11B
Protein found in humans
et al. (2006). "Identification of truncated RUNX1 and RUNX1-PRDM16 fusion transcripts in a case of t(1;21)(p36;q22)-positive therapy-related AML". Leukemia
PRDM16
Area of research which persists despite being widely discredited
Examples of pathological science include the Martian canals, N-rays, and cold fusion. The theories and conclusions behind all of these examples are currently
Pathological_science
Protein found in humans
Kazmierczak B, Bullerdiek J (December 2000). "An identical HMGIC-LPP fusion transcript is consistently expressed in pulmonary chondroid hamartomas with
HMGA2
American broadcaster
Daily Dot. Twitch Boosts A New Pro Category: Video Game Player (radio, transcript). NPR. April 4, 2014. Laura Sydell: Twitch Boosts A New Pro Category:
ManvsGame
Process of copying a segment of DNA into RNA
polymerase, which produces a complementary RNA strand called a primary transcript. In virology, the term transcription is used when referring to mRNA synthesis
Transcription_(biology)
American physicist
Polywell Reactor Transcript of Bussard Polywell Interview, May 10, 2007 Robert Bussard on Fusion Drives, NERVA & the Bussard Ramjet Transcript of Bussard Space
Robert_W._Bussard
Protein domain
of the two genes in the BCR-ABL fusion protein, which is associated with the Philadelphia chromosome. Two transcript variants encoding different isoforms
Breakpoint cluster region protein
Breakpoint_cluster_region_protein
History of technical design of modern hydrogen bombs
compress and ignite nuclear fusion in a secondary. This is in contrast to the simpler design and usage of nuclear fusion in boosted fission weapons. The
History of the Teller–Ulam design
History_of_the_Teller–Ulam_design
Protein-coding gene in the species Homo sapiens
J, Stenman G (2002). "Expression of PLAG1 and HMGIC proteins and fusion transcripts in radiation-associated pleomorphic adenomas". Int. J. Oncol. 20 (4):
PLAG1
Single nucleic acid sequence created from fragments that are normally separated
sequencing, a chimera is a single DNA sequence originating when multiple transcripts or DNA sequences get joined. Chimeras can be considered artifacts and
Chimera_(molecular_biology)
Carbonated soft drink
(December 13, 2008). "Axl answers fans' questions on GN'R fan sites (transcripts)". HereTodayGoneToHell.com. Archived from the original on June 15, 2009
Dr_Pepper
The White House corroborated allegations raised by the whistleblower. A transcript of the Trump–Zelenskyy call confirmed Trump requested investigations into
2019_Trump–Ukraine_scandal
Protein-coding gene in the species Homo sapiens
"Molecular diagnosis of synovial sarcoma: RT-PCR detection of SYT-SSX1/2 fusion transcripts in paraffin-embedded tissue". Med. Sci. Monit. 11 (3): MT1–7. PMID 15735574
SSX1
American inventor (1906–1971)
invented a small nuclear fusion device, the Farnsworth Fusor, employing inertial electrostatic confinement (IEC). Like many fusion devices, it was not a
Philo_Farnsworth
Protein-coding gene in humans
A medically important aspect of the FIP1L1 gene is its fusion with other genes to form fusion genes which cause clonal hypereosinophilia and leukemic
FIP1L1
American journalist (born 1975)
hit the country. Ruhle also appeared in Shark Land: A Mission Blue and Fusion Expedition (2015), which brings attention to the plight of sharks in Cocos
Stephanie_Ruhle
Political opposition research report regarding the 2016 US election
Release Fusion GPS Transcript From Russia Probe". Bloomberg News. Retrieved January 9, 2018. Barrett, Devlin; Hamburger, Tom (January 9, 2018). "Fusion GPS
Steele_dossier
British theoretical physicist
1959) is a British fusion and astrophysical theoretical plasma physicist. He has served as director of the UKAEA Culham Centre for Fusion Energy between 2009
Steven_Cowley
Protein found in humans
in multiple transcript variants. A read-through transcript from the upstream TRIM6 gene has also been observed, which results in a fusion product from
Tripartite motif containing 34
Tripartite_motif_containing_34
Protein
Size (bp) Transcript Variant 1 NM_022483 3 2736 Transcript Variant 2 NM_001377394.1 4 2887 Transcript Variant X2 XM_011514075 4 3574 Transcript Variant
TMEM267
Human protein and coding gene
DNA damage-inducible transcript 3, also known as C/EBP homologous protein (CHOP), is a pro-apoptotic transcription factor that is encoded by the DDIT3
DNA damage-inducible transcript 3
DNA_damage-inducible_transcript_3
Protein-coding gene in the species Homo sapiens
(charged multivesicular body protein 3) genes. The read-through transcript encodes a fusion protein that shares sequence identity with each individual gene
RNF103-CHMP3_readthrough
cell fusion peptides for fusion. This protein is coded by the canonical transcript as NP_003805.4, whereas the other predicted alternate transcripts have
ADAM20
Protein-coding gene in the species Homo sapiens
of therapy-related myelodysplasia with NUP98-DDX10 and DDX10-NUP98 fusion transcripts". Int. J. Hematol. 69 (3): 160–4. PMID 10222653. Liang WQ, Clark JA
DDX10
Protein-coding gene in the species Homo sapiens
"Activation of a novel gene in 3q21 and identification of intergenic fusion transcripts with ecotropic viral insertion site I in leukemia". Cancer Res. 57
RPN1
Video-sharing platform
(conference). Archived from the original on December 2, 2013. (click on "Show transcript" tab) • Corresponding YouTube video from official TED channel was titled
YouTube
Type of excimer laser
Pethokoukis, James (2024-04-11). "⚡⚛ My chat (+transcript) with Steve Obenschain of LaserFusionX on laser fusion". Faster, Please!. Retrieved 2024-04-12.
Argon_fluoride_laser
American political advisor (born 1985)
crime". NBC News. Retrieved September 15, 2025. "Aired January 5, 2026". transcripts.cnn.com. "Stephen Miller and the Amnesic Hypocrisy of His Ideology".
Stephen_Miller
Mammalian protein found in Homo sapiens
development. Specifically, syncytin-1 and syncytin-2 facilitate trophoblast fusion, a critical process in placenta formation. Suppressyn is a 160 amino acid
Suppressyn
President of the United States from 2001 to 2009
John Kerry's Shifting Positions on Iraq War Spending". Fox News Network (transcript). Cain, Áine (February 19, 2018). "29 American presidents who served in
George_W._Bush
Industrialist and technologist (born 1971)
Oliver (January 22, 2025). "Elon Musk admits cheating at video games, chat transcript appears to show". The Guardian. "Gamers Disgusted as Elon Musk Admits
Elon_Musk
Political party
Allies of White Supremacy". ISSN 0027-8378. Retrieved September 29, 2026. "Transcript: Trump's Support Among Minority Voters Has Collapsed". November 15, 2025
Republican Party (United States)
Republican_Party_(United_States)
Mayor of New York City since 2026
Kampala in 1991" (Tweet). Retrieved October 6, 2026 – via Twitter. "Transcript: Mayor Mamdani Hosts African Heritage Reception". nyc.gov. September 9
Zohran_Mamdani
American politician and activist (born 1989)
"Shields and Brooks on Cohen testimony, North Korea summit". PBS NewsHour (Transcript). Archived from the original on March 2, 2019. Retrieved March 2, 2019
Alexandria_Ocasio-Cortez
Specialized typewriter or chorded keyboard for recording in shorthand
draft of their transcript, then proofread and certify the transcript themselves, or they may use neither and produce a final transcript by themselves,
Stenotype
travel, tourism, insurance
FUSION TRANSCRIPT
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travel, tourism, insurance