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CYCLIN B1

  • Cyclin B1
  • Protein-coding gene in the species Homo sapiens

    G2/mitotic-specific cyclin-B1 is a protein that in humans is encoded by the CCNB1 gene. Cyclin B1 is a regulatory protein involved in mitosis. The gene

    Cyclin B1

    Cyclin B1

    Cyclin_B1

  • G2 phase
  • Third subphase of interphase

    threshold level of active cyclin-B1/CDK1 complex, also known as cyclin-B1/Cdc2 or the maturation promoting factor (MPF). Active cyclin-B1/CDK1 triggers irreversible

    G2 phase

    G2 phase

    G2_phase

  • Cyclin
  • Group of proteins

    Cyclins are proteins that control the progression of a cell through the cell cycle by activating cyclin-dependent kinases (CDK). Cyclins were originally

    Cyclin

    Cyclin

    Cyclin

  • Cyclin B
  • Protein family

    Cyclin B is a member of the cyclin family. Cyclin B is a mitotic cyclin. The amount of cyclin B (which binds to Cdk1) and the activity of the cyclin B-Cdk

    Cyclin B

    Cyclin B

    Cyclin_B

  • Cyclin-dependent kinase 1
  • Mammalian protein found in Homo sapiens

    Ollendorff V, Donoghue DJ (March 2000). "Cyclin F regulates the nuclear localization of cyclin B1 through a cyclin-cyclin interaction". The EMBO Journal. 19

    Cyclin-dependent kinase 1

    Cyclin-dependent kinase 1

    Cyclin-dependent_kinase_1

  • Cyclin-dependent kinase
  • Class of enzymes

    CDK to a subcellular area where the substrate is found. For example, cyclin B1 and B2 can localize CDK1 to the nucleus and the Golgi, respectively, through

    Cyclin-dependent kinase

    Cyclin-dependent kinase

    Cyclin-dependent_kinase

  • Cyclin B2
  • Protein-coding gene in the species Homo sapiens

    cyclins. The B-type cyclins, B1 and B2, associate with p34cdc2 and are essential components of the cell cycle regulatory machinery. B1 and B2 differ in their

    Cyclin B2

    Cyclin B2

    Cyclin_B2

  • Cyclin A2
  • Protein-coding gene in the species Homo sapiens

    promoting factor (MPF). Recent studies have shown that the cyclin A2-CDK1 complex triggers cyclin B1-CDK1 activation which results in chromatin condensation

    Cyclin A2

    Cyclin A2

    Cyclin_A2

  • Cyclin B3
  • Cell cycle protein

    other previously characterized invertebrate or vertebrate cyclin B3s. Unlike cyclin B1 and cyclin B2, it is solely expressed in germ cells in mammals, with

    Cyclin B3

    Cyclin B3

    Cyclin_B3

  • Mitotic catastrophe
  • Mechanism of cell death

    phenomenon is caused by improper degradation of cyclin B1 and can result in chromosome missegregation events. Cyclin B1 is a major regulator of the cell cycle

    Mitotic catastrophe

    Mitotic catastrophe

    Mitotic_catastrophe

  • Ultrasensitivity
  • intermediate levels of Cyclin B1, and the transition between the two stable states is abrupt when increasing levels of Cyclin B1 switches the system from

    Ultrasensitivity

    Ultrasensitivity

    Ultrasensitivity

  • Mitotic exit
  • checkpoints. Many factors including cyclins, cyclin-dependent kinases (CDKs), ubiquitin ligases, inhibitors of cyclin-dependent kinases, and reversible

    Mitotic exit

    Mitotic_exit

  • G0 phase
  • Quiescent stage of the cell cycle in which the cell does not divide

    involves downregulation of cell cycle progression genes, such as cyclin A2, cyclin B1, cyclin E2, and survivin, and upregulation of genes involved in the regulation

    G0 phase

    G0 phase

    G0_phase

  • Cell cycle analysis
  • Biological measurement technique

    analysis that includes measurement of expression of cyclin D1, cyclin E, cyclin A and cyclin B1, each in relation to DNA content Concurrent measurement

    Cell cycle analysis

    Cell_cycle_analysis

  • Cell division
  • Biological process

    Lindqvist A, van Zon W, Karlsson Rosenthal C, Wolthuis RM (May 2007). "Cyclin B1-Cdk1 activation continues after centrosome separation to control mitotic

    Cell division

    Cell division

    Cell_division

  • Spindle apparatus
  • Feature of biological cell structure

    considered the main mitotic kinase in mammalian cells and is activated by Cyclin B1. Aurora kinases are required for proper spindle assembly and separation

    Spindle apparatus

    Spindle apparatus

    Spindle_apparatus

  • Cyclin A1
  • Protein-coding gene in the species Homo sapiens

    "G2 delay induced by nitrogen mustard in human cells affects cyclin A/cdk2 and cyclin B1/cdc2-kinase complexes differently". J. Biol. Chem. 268 (11):

    Cyclin A1

    Cyclin A1

    Cyclin_A1

  • S100A4
  • Protein-coding gene in the species Homo sapiens

    from proteins that contribute to metastasis, such as cathepsin B and cyclin B1. Together, these factors form polyploid giant cancer cells (PGCCs), which

    S100A4

    S100A4

    S100A4

  • Separase
  • Mammalian protein found in Homo sapiens

    human separase were determined in complex with either securin or CDK1-cyclin B1-CKS1 using cryo-EM by scientists of the University of Geneva. Stable cohesion

    Separase

    Separase

    Separase

  • Basal-like carcinoma
  • Breast cancer subtype

    Overgaard J, et al. (June 2009). "Integrative analysis of cyclin protein levels identifies cyclin b1 as a classifier and predictor of outcomes in breast cancer"

    Basal-like carcinoma

    Basal-like carcinoma

    Basal-like_carcinoma

  • Xin Lu
  • Chinese and British oncologist

    "Restoring p53 Function in Human Melanoma Cells by Inhibiting MDM2 and Cyclin B1/CDK1-Phosphorylated Nuclear iASPP". Cancer Cell. 23 (5): 618–633. doi:10

    Xin Lu

    Xin_Lu

  • GADD45G
  • Protein-coding gene in the species Homo sapiens

    with CRIF, which causes the inhibition of Cdc2-cyclin B1 and Cdk-cyclin E. GADD45 also works with the cyclin-dependent kinase inhibitor p21, which can cause

    GADD45G

    GADD45G

    GADD45G

  • Biochemical switches in the cell cycle
  • experiments in both human cells and starfish oocytes, Jin et al. summarize that cyclin B1 is abundant in the cytoplasm during non-dividing phases of mitosis, but

    Biochemical switches in the cell cycle

    Biochemical_switches_in_the_cell_cycle

  • Hitoshi Okamura
  • Japanese scientist (born 1952)

    that cyclin B1 and cdc2 were positively correlated. They also found that wee1, the gene for a kinase that inhibits mitosis by inactivating CDC2/cyclin B

    Hitoshi Okamura

    Hitoshi_Okamura

  • CPEB1
  • Protein-coding gene in humans

    their translation. Members of this protein family regulate translation of cyclin B1 during embryonic cell divisions. Multiple transcript variants encoding

    CPEB1

    CPEB1

    CPEB1

  • Reprimo
  • Cdc2 expression, and in the inhibition of the nuclear translocation of cyclin B1 which is necessary to its function. Reprimo is known to collaborate with

    Reprimo

    Reprimo

  • PAK1
  • Mammalian protein found in Homo sapiens

    vascular endothelial growth factor, Cyclin D1, phosphofructokinase-muscle isoform, nuclear factor of activated T-cell, Cyclin B1, Tissue Factor and tissue factor

    PAK1

    PAK1

    PAK1

  • Mir-744 microRNA precursor family
  • RNA family

    lines. Its expression induces cyclin B1 expression, whilst knockdown sees a resultant decreased level of mouse cyclin B through the Ccnb1 gene. Short-term

    Mir-744 microRNA precursor family

    Mir-744_microRNA_precursor_family

  • HSPA1B
  • Human gene

    where it is necessary for the formation of the complex between CDC2 and cyclin B1. It later becomes incorporated into the CatSper complex, a specialized

    HSPA1B

    HSPA1B

    HSPA1B

  • GADD45A
  • Protein-coding gene in the species Homo sapiens

    Fornace AJ (May 1999). "Association with Cdc2 and inhibition of Cdc2/Cyclin B1 kinase activity by the p53-regulated protein Gadd45". Oncogene. 18 (18):

    GADD45A

    GADD45A

    GADD45A

  • Mitotic cell rounding
  • Shape change in animal cells

    Chen, Nan-Peng; Aretz, Jonas; Faessler, Reinhard (24 May 2022). "CDK1-cyclin-B1-induced kindlin degradation drives focal adhesion disassembly at mitotic

    Mitotic cell rounding

    Mitotic_cell_rounding

  • CPEB
  • Protein

    "Cytoplasmic polyadenylation elements mediate masking and unmasking of cyclin B1 mRNA". The EMBO Journal. 18 (8): 2294–2303. doi:10.1093/emboj/18.8.2294

    CPEB

    CPEB

    CPEB

  • Cell cycle
  • Events leading to cell division

    R, Engler J, Verkest A, Beeckman T, Naudts M, et al. (April 2004). "B1-type cyclin-dependent kinases are essential for the formation of stomatal complexes

    Cell cycle

    Cell cycle

    Cell_cycle

  • Cytoplasmic polyadenylation element
  • RNA sequence

    (1999). "Cytoplasmic polyadenylation mediate masking and unmasking of cyclin B1 mRNA". EMBO J. 18 (8): 2294–2303. doi:10.1093/emboj/18.8.2294. PMC 1171312

    Cytoplasmic polyadenylation element

    Cytoplasmic_polyadenylation_element

  • Jonathon Pines
  • British oncologist (born 1961)

    their localisation. Recently, he discovered that the mitotic kinase, cyclin B1-Cdk1 is activated on centrosomes, and thereby prompted considerable interest

    Jonathon Pines

    Jonathon Pines

    Jonathon_Pines

  • Endoreduplication
  • Replication of the nuclear genome without mitosis

    cycle in polyploid megakaryocytes is associated with reduced activity of cyclin B1-dependent cdc2 kinase". Journal of Biological Chemistry. 271 (8): 4266–72

    Endoreduplication

    Endoreduplication

  • CCNF
  • Protein-coding gene in humans

    G2/mitotic-specific cyclin-F is a protein that in humans is encoded by the CCNF gene. This gene encodes a member of the cyclin family. Cyclins are important

    CCNF

    CCNF

    CCNF

  • DNM1L
  • Protein-coding gene in humans

    mitochondria and encouraging mitochondrial- related necrosis. In addition, cyclin B1- CDK activates Drp1, causing fragmentation and ensuring mitochondria are

    DNM1L

    DNM1L

    DNM1L

  • CCNG1
  • Protein-coding gene in humans

    Kobayashi S, Imaida K, Maeta H, Ishida T, Kuriyama S (2003). "Cyclin B1, unlike cyclin G1, increases significantly during colorectal carcinogenesis and

    CCNG1

    CCNG1

    CCNG1

  • CCNB
  • Topics referred to by the same term

    CCNB may stand for: Collège communautaire du Nouveau-Brunswick Cyclin B1 This disambiguation page lists articles associated with the title CCNB. If an

    CCNB

    CCNB

  • ZC3HC1
  • Protein-coding gene in the species Homo sapiens

    of which is regulated by cell-cycle-dependent phosphorylation of NIPA. Cyclin B1, essential in the entry into mitosis, is targeted by SCFNIPA in interphase

    ZC3HC1

    ZC3HC1

    ZC3HC1

  • Callystatin A
  • Chemical compound

    molecules include regulatory proteins such as Rev, MAPK/MEK1, c-Abl, Cyclin B1, MDM2/p53, IkB, MPF, and PKA. The most important role of leptomycin B

    Callystatin A

    Callystatin A

    Callystatin_A

  • RNA activation
  • Biological gene-regulation phenomenon

    Z; Yu, A; Shuman, M; Yu, J; Li, LC (February 2012). "Upregulation of Cyclin B1 by miRNA and its implications in cancer". Nucleic Acids Research. 40 (4):

    RNA activation

    RNA_activation

  • HIST1H1A
  • Protein-coding gene in the species Homo sapiens

    "G2 delay induced by nitrogen mustard in human cells affects cyclin A/cdk2 and cyclin B1/cdc2-kinase complexes differently". J. Biol. Chem. 268 (11):

    HIST1H1A

    HIST1H1A

    HIST1H1A

  • CCNB1IP1
  • Protein-coding gene in humans

    Cyclin B Levels". Mol Cell Biol. 23 (6): 2109–2122. doi:10.1128/MCB.23.6.2109-2122.2003. PMC 149478. PMID 12612082. "Entrez Gene: CCNB1IP1 cyclin B1 interacting

    CCNB1IP1

    CCNB1IP1

    CCNB1IP1

  • PKMYT1
  • Protein-coding gene in the species Homo sapiens

    of the Golgi apparatus and the Endoplasmic reticulum. Since almost all cyclin B1-Cdk 1 complexes are found in the cytoplasm, Myt 1 may be the most important

    PKMYT1

    PKMYT1

    PKMYT1

  • RUNX2
  • Protein-coding gene in humans

    shown that on a molecular level, Runx associates with the cdc2 partner cyclin B1 during mitosis. The phosphorylation state of Runx2 also mediates its DNA-binding

    RUNX2

    RUNX2

    RUNX2

  • Brivanib alaninate
  • Chemical compound

    and down-regulation of cell cycle regulators, including cyclin D1, Cdk-2, Cdk-4, cyclin B1, and phospho-c-Myc. Based on this study, researchers have

    Brivanib alaninate

    Brivanib alaninate

    Brivanib_alaninate

  • MOS (gene)
  • Protein-coding gene in the species Homo sapiens

    Lanzendorf SE, Baka SG, Gibbons WE (1995). "Cell cycle genes c-mos and cyclin-B1 are expressed in a specific pattern in human oocytes and preimplantation

    MOS (gene)

    MOS (gene)

    MOS_(gene)

  • Gadd45
  • other proteins implicated in stress responses, including PCNA, p21, Cdc2/CyclinB1, MEKK4, and p38 kinase. GADD45 proteins regulate differentiation at the

    Gadd45

    Gadd45

  • MASTL
  • Protein-coding gene in the species Homo sapiens

    form 4N G1 cells due to cytokinesis failure. This enzyme enhances the cyclin B1-Cdk1-dependent mitotic phosphorylation events during mitosis. Although

    MASTL

    MASTL

    MASTL

  • Kruppel-like factors
  • Family of zinc finger transcription factors

    through activation of p21Cip1/Waf1, and direct suppression of cyclin D1 and cyclin B1 gene expression. Both Klf4 & Klf5 proteins act on the Klf4 promoter

    Kruppel-like factors

    Kruppel-like_factors

  • RALBP1
  • Protein-coding gene in the species Homo sapiens

    is encoded by the RALBP1 gene. RALBP1 has been shown to interact with: Cyclin B1, HSF1, RALA, RALB, and REPS2. GRCh38: Ensembl release 89: ENSG00000017797

    RALBP1

    RALBP1

    RALBP1

  • MXI1
  • Protein-coding gene in humans

    inhibits the proliferation of U87 glioma cells through down-regulation of cyclin B1 gene expression". Br. J. Cancer. 86 (3): 477–84. doi:10.1038/sj.bjc.6600065

    MXI1

    MXI1

    MXI1

  • CDC25B
  • Protein-coding gene in humans

    PMID 9278511. Jin P, Hardy S, Morgan DO (1998). "Nuclear Localization of Cyclin B1 Controls Mitotic Entry After DNA Damage". J. Cell Biol. 141 (4): 875–85

    CDC25B

    CDC25B

    CDC25B

  • GADD45B
  • Protein-coding gene in the species Homo sapiens

    AG, Hoffman B, Liebermann DA (Sep 2002). "GADD45b and GADD45g are cdc2/cyclinB1 kinase inhibitors with a role in S and G2/M cell cycle checkpoints induced

    GADD45B

    GADD45B

    GADD45B

  • CDC25C
  • Protein-coding gene in humans

    belongs to the Cdc25 phosphatase family. It directs dephosphorylation of cyclin B-bound CDC2 (CDK1) and triggers entry into mitosis. It is also thought

    CDC25C

    CDC25C

    CDC25C

  • TGF beta 1
  • Protein-coding gene in the species Homo sapiens

    "Survival and cell cycle control in early hematopoiesis: role of bcl-2, and the cyclin dependent kinase inhibitors P27 and P21". Leukemia & Lymphoma. 43 (1): 51–57

    TGF beta 1

    TGF beta 1

    TGF_beta_1

  • Nuclear lamina
  • Fibrillar network

    their kinetochores. These different disassembly events are initiated by the cyclin B/Cdk1 protein kinase complex (MPF). Once this complex is activated, the

    Nuclear lamina

    Nuclear lamina

    Nuclear_lamina

  • Retinoblastoma protein
  • Mammalian protein found in humans

    example of E2F-regulated genes repressed by pRb are cyclin E and cyclin A. Both of these cyclins are able to bind to Cdk2 and facilitate entry into the

    Retinoblastoma protein

    Retinoblastoma protein

    Retinoblastoma_protein

  • BRAF (gene)
  • Protein-coding gene in humans

    2.7.11.21-EC 2.7.11.30) Polo kinase (EC 2.7.11.21) PLK1 PLK2 PLK3 PLK4 Cyclin-dependent kinase (EC 2.7.11.22) CDK1 CDK2 CDKL2 CDK3 CDK4 CDK5 CDKL5 CDK6

    BRAF (gene)

    BRAF (gene)

    BRAF_(gene)

  • Transcription factor II H
  • Protein complex

    the core complex. The remaining three subunits—CDK7, MAT1, and cyclin H—form the cyclin-activating kinase (CAK) subcomplex, which is tethered to the core

    Transcription factor II H

    Transcription_factor_II_H

  • DNA end resection
  • Process involved in DNA repair

    nucleolytic degradation of DNA ends. Along with cdk1, the MRX complex, B1 cyclin, and Spo11-induced DSBs serve as a positive regulators to the HR pathway

    DNA end resection

    DNA end resection

    DNA_end_resection

  • MyoD
  • Mammalian protein found in Homo sapiens

    repression of the D1 cyclin. Both MyoD and pRb are necessary for the repression of cyclin D1, but rather than acting directly on cyclin D1, they act on Fra-1

    MyoD

    MyoD

    MyoD

  • Control of chromosome duplication
  • origins. Removal of cyclin E with antibodies blocks replication. Cyclin E-CDk2 is also important in Drosophila. Levels of cyclin E rise during S phase

    Control of chromosome duplication

    Control of chromosome duplication

    Control_of_chromosome_duplication

  • MAPRE3
  • Protein-coding gene in the species Homo sapiens

    positive regulation of microtubule plus-end binding positive regulation of cyclin-dependent protein serine/threonine kinase activity cell division protein

    MAPRE3

    MAPRE3

    MAPRE3

  • E2F
  • Family of transcription factors

    The phosphorylation of pRB is initiated by cyclin D/cdk4, cdk6 complex and continued by cyclin E/cdk2. Cyclin D/cdk4,6 itself is activated by the MAPK signaling

    E2F

    E2F

  • P53
  • Mammalian protein found in humans

    including CDKN1A, which encodes p21. Upon activation by p53, p21 inhibits cyclin-dependent kinases, leading to cell cycle arrest and contributing to tumor

    P53

    P53

    P53

  • Maternal to zygotic transition
  • Stage in embryonic development

    as Cyclin A1 and Cyclin B2. Lee MT, Bonneau AR, Takacs CM, Bazzini AA, DiVito KR, Fleming ES, Giraldez AJ (November 2013). "Nanog, Pou5f1 and SoxB1 activate

    Maternal to zygotic transition

    Maternal_to_zygotic_transition

  • Ubiquitin
  • Regulatory protein found in most eukaryotic tissues

    degradation. SKP2 targets p27Kip-1, an inhibitor of cyclin-dependent kinases (CDKs). CDKs2/4 partner with the cyclins E/D, respectively, forming a family of cell

    Ubiquitin

    Ubiquitin

    Ubiquitin

  • E2F1
  • Protein-coding gene in the species Homo sapiens

    promoter[PAX8] => E2F1 E2F1 has been shown to interact with: ARID3A, CUL1, Cyclin A1, Cyclin A2, GTF2H1, MDM4, NCOA6, NDN, NPDC1, PURA, PHB, RB1, UDG, RBL1, SKP2

    E2F1

    E2F1

    E2F1

  • Long non-coding RNA
  • Non-protein coding transcripts longer than 200 nucleotides

    acetyltransferase activities on a repressed gene target, cyclin D1. The recruitment of TLS to the promoter of cyclin D1 is directed by long ncRNAs expressed at low

    Long non-coding RNA

    Long non-coding RNA

    Long_non-coding_RNA

  • Eukaryotic DNA replication
  • DNA replication in eukaryotic organisms

    activation and inactivation of cyclin-dependent kinases (Cdks, CDKs). Specifically it is the interactions of cyclins and cyclin dependent kinases that are

    Eukaryotic DNA replication

    Eukaryotic DNA replication

    Eukaryotic_DNA_replication

  • List of MeSH codes (D12.776)
  • cerevisiae MeSH D12.776.167.200.067.875 – cyclin-dependent kinase 5 MeSH D12.776.167.200.067.900 – cyclin-dependent kinase 9 MeSH D12.776.167.200.580

    List of MeSH codes (D12.776)

    List_of_MeSH_codes_(D12.776)

  • CDC34
  • Protein-coding gene in humans

    the cell cycle. Cdc34 in yeast targets numerous substrates - notably the cyclin-dependent kinase inhibitor Sic1 - for ubiquitin-mediated protein degradation

    CDC34

    CDC34

    CDC34

  • STK11
  • Protein-coding gene in the species Homo sapiens

    Serine/threonine kinase 11 (STK11) also known as liver kinase B1 (LKB1) or renal carcinoma antigen NY-REN-19 is a protein kinase that in humans is encoded

    STK11

    STK11

    STK11

  • Retinoblastoma-like protein 2
  • Protein-coding gene in the species Homo sapiens

    Retinoblastoma-like protein 2 has been shown to interact with: BRCA1, BRF1 C-Raf, Cyclin E1, Cyclin-dependent kinase 2, HDAC1, Prohibitin, and RBBP8. Mutations in RBL2

    Retinoblastoma-like protein 2

    Retinoblastoma-like protein 2

    Retinoblastoma-like_protein_2

  • Titin
  • Largest known protein in human muscles

    2.7.11.21-EC 2.7.11.30) Polo kinase (EC 2.7.11.21) PLK1 PLK2 PLK3 PLK4 Cyclin-dependent kinase (EC 2.7.11.22) CDK1 CDK2 CDKL2 CDK3 CDK4 CDK5 CDKL5 CDK6

    Titin

    Titin

    Titin

  • MYBL2
  • Protein-coding gene in the species Homo sapiens

    in cell cycle progression. The encoded protein is phosphorylated by cyclin A/cyclin-dependent kinase 2 during the S-phase of the cell cycle and possesses

    MYBL2

    MYBL2

    MYBL2

  • Human papillomavirus infection
  • Human disease

    p53 also upregulates the p21 protein, which blocks the formation of the cyclin D/Cdk4 complex, thereby preventing the phosphorylation of retinoblastoma

    Human papillomavirus infection

    Human papillomavirus infection

    Human_papillomavirus_infection

  • Ubiquitin ligase
  • Protein

    key players in cell cycle control, mediating the degradation of cyclins, as well as cyclin dependent kinase inhibitor proteins. The human genome encodes

    Ubiquitin ligase

    Ubiquitin ligase

    Ubiquitin_ligase

  • ALDH1B1
  • Protein-coding gene in the species Homo sapiens

    Triche TJ, He Q, Wu L (Oct 2007). "Intrinsic retinoic acid receptor alpha-cyclin-dependent kinase-activating kinase signaling involves coordination of the

    ALDH1B1

    ALDH1B1

    ALDH1B1

  • Lateral root
  • Plant root

    Inze, Dirk (December 1994). "Developmental Expression of the Arabidopsis Cyclin Gene cyc1At". The Plant Cell. 6 (12): 1763–1774. Bibcode:1994PlanC...6.1763F

    Lateral root

    Lateral root

    Lateral_root

  • Forkhead box protein O1
  • Protein

    arrest is linked with cyclin D1 and cyclin D2 suppression in mammals. It was detected that human FOXO1 is linked with the cyclin D1 promoter using chromatin

    Forkhead box protein O1

    Forkhead box protein O1

    Forkhead_box_protein_O1

  • Epidermal growth factor receptor
  • Transmembrane protein

    mediated signal transduction cell differentiation positive regulation of cyclin-dependent protein serine/threonine kinase activity negative regulation of

    Epidermal growth factor receptor

    Epidermal growth factor receptor

    Epidermal_growth_factor_receptor

  • E2F3
  • Protein-coding gene in the species Homo sapiens

    This protein and another 2 members, E2F1 and E2F2, have an additional cyclin binding domain. This protein binds specifically to retinoblastoma protein

    E2F3

    E2F3

    E2F3

  • Encorafenib
  • Chemical compound

    kinase inhibitor, decreasing ERK phosphorylation and down-regulation of CyclinD1. This arrests the cell cycle in G1 phase, inducing senescence without

    Encorafenib

    Encorafenib

    Encorafenib

  • Caspase 3
  • Protein found in humans

    peptidase activity protein binding phospholipase A2 activator activity cyclin-dependent protein serine/threonine kinase inhibitor activity cysteine-type

    Caspase 3

    Caspase 3

    Caspase_3

  • Retinoblastoma-like protein 1
  • Mammalian protein found in Homo sapiens

    Retinoblastoma-like protein 1 has been shown to interact with: BEGAIN, BRCA1, BRF1, Cyclin A2, Cyclin-dependent kinase 2, E2F1, HDAC1, MYBL2 Mothers against decapentaplegic

    Retinoblastoma-like protein 1

    Retinoblastoma-like protein 1

    Retinoblastoma-like_protein_1

  • Schumanniophyton problematicum
  • Species of plant

    treatment of animal models of rheumatoid arthritis with small-molecule cyclin-dependent kinase inhibitors". J. Immunol. 180 (3): 1954–61. doi:10.4049/jimmunol

    Schumanniophyton problematicum

    Schumanniophyton problematicum

    Schumanniophyton_problematicum

  • PPP2CA
  • Protein-coding gene in humans

    interact with: Bcl-2, Bestrophin 1, CCNG2, CTTNBP2NL, CTTNBP2, Cyclin-dependent kinase 2, Cyclin-dependent kinase 6, FAM40A, IGBP1, MOBKL3, PPP2R1A, PPP2R1B

    PPP2CA

    PPP2CA

    PPP2CA

  • Androgen receptor
  • Mammalian protein found in humans

    C-jun, Calmodulin 1, Caveolin 1, CDK9, COX5B, CREB-binding protein, Cyclin D1, Cyclin-dependent kinase 7, DACH1, Death associated protein 6, L-DOPA, EFCAB6

    Androgen receptor

    Androgen receptor

    Androgen_receptor

  • UBE2C
  • Protein-coding gene in the species Homo sapiens

    Aristarkhov A, Beck S, Hershko A, Ruderman JV (Apr 1997). "Dominant-negative cyclin-selective ubiquitin carrier protein E2-C/UbcH10 blocks cells in metaphase"

    UBE2C

    UBE2C

    UBE2C

  • Von Hippel–Lindau tumor suppressor
  • Mammalian protein found in humans

    interacts with cyclin D1. This leads to increased survival due to lower rates of apoptosis and increased proliferation due to the activation of cyclin D1. Recent

    Von Hippel–Lindau tumor suppressor

    Von Hippel–Lindau tumor suppressor

    Von_Hippel–Lindau_tumor_suppressor

  • Allograft inflammatory factor 1
  • Protein-coding gene in the species Homo sapiens

    Upregulation of AIF-1 enhanced activity of NF-ΚB and increased expression of cyclin D1. Cyclin D1 contribute to cell proliferation and mutation in this gene has

    Allograft inflammatory factor 1

    Allograft inflammatory factor 1

    Allograft_inflammatory_factor_1

  • P70-S6 Kinase 1
  • Protein-coding gene in the species Homo sapiens

    2.7.11.21-EC 2.7.11.30) Polo kinase (EC 2.7.11.21) PLK1 PLK2 PLK3 PLK4 Cyclin-dependent kinase (EC 2.7.11.22) CDK1 CDK2 CDKL2 CDK3 CDK4 CDK5 CDKL5 CDK6

    P70-S6 Kinase 1

    P70-S6 Kinase 1

    P70-S6_Kinase_1

  • NRF1
  • Protein-coding gene in the species Homo sapiens

    isoforms have been described but they have not been fully characterized. Cyclin D1-dependent kinase, through phosphorylating NRF-1 at S47, coordinates nuclear

    NRF1

    NRF1

    NRF1

  • SH3GLB1
  • Protein-coding gene in the species Homo sapiens

    Endophilin-B1 is a protein that in humans is encoded by the SH3GLB1 gene. Endophilin-B1 belongs to the Bin/Amphiphysin/Rvs167 (BAR) family of proteins

    SH3GLB1

    SH3GLB1

    SH3GLB1

  • HLA-F
  • Protein-coding gene in the species Homo sapiens

    pathways include IFN-gamma signaling and CDK-mediated phosphorylation (cyclin-dependent kinase) and removal of the Saccharomyces cerevisiae Cdc6 protein

    HLA-F

    HLA-F

    HLA-F

  • Receptor for activated C kinase 1
  • Protein-coding gene in the species Homo sapiens

    RACK1 has been shown to interact with: AGTRAP Androgen receptor, CD18, CD29 Cyclin A1 EIF6, FYN, IFNAR2, Janus kinase 1 OTUB1, P73, PDE4D, PRKCB1, PRKCE, PTPRM

    Receptor for activated C kinase 1

    Receptor for activated C kinase 1

    Receptor_for_activated_C_kinase_1

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  • Catlin
  • Surname or Lastname

    English

    Catlin

    English : from the medieval female personal name Cat(e)lin(e), Anglo-Norman French form of Catherine.

    Catlin

  • Carlin
  • Boy/Male

    Gaelic German Irish

    Carlin

    Small champion.

    Carlin

  • Bhawar
  • Boy/Male

    Indian, Sikh

    Bhawar

    Cyclone

    Bhawar

  • Catlin
  • Girl/Female

    Irish

    Catlin

    meaning pure.

    Catlin

  • Cailin
  • Boy/Male

    Scottish

    Cailin

    Contemporary'Child.

    Cailin

  • Coilin
  • Boy/Male

    Gaelic Irish

    Coilin

    Virile.

    Coilin

  • AYLIN
  • Female

    Turkish

    AYLIN

    Turkish name AYLIN means "moon halo."

    AYLIN

  • Cocklin
  • Surname or Lastname

    English

    Cocklin

    English : from a diminutive of Middle English cok ‘cock’ (see Cocke).Perhaps also an Americanized spelling of Swiss and South German Köchlin, Koechlin, or Köchling, all diminutives of Koch.

    Cocklin

  • Collin
  • Boy/Male

    Gaelic American Irish English French

    Collin

    child.

    Collin

  • Collin
  • Surname or Lastname

    English and French

    Collin

    English and French : from a pet form of English Coll 1, French Colle.Probably an altered spelling of German Kollin.Danish : variant of Colding.Swedish : ornamental name from an unexplained first element, probably from a place name, + the the suffix -in, from Latin -in(i)us ‘descendant of’.

    Collin

  • Cullin
  • Boy/Male

    Gaelic Irish

    Cullin

    Handsome; good-looking lad.

    Cullin

  • Caplin
  • Surname or Lastname

    English

    Caplin

    English : occupational name for a chantry priest (or the servant of one), a priest endowed to sing mass daily on behalf of the souls of the dead (Late Latin capellanus). Compare Chaplin.Americanized spelling of Swiss German Kaeppelin, a diminutive of Kappel.

    Caplin

  • Colin
  • Surname or Lastname

    French

    Colin

    French : from a reduced pet form of the personal name Nicolas (see Nicholas).English : variant spelling of Collin.A Colin from Brittany, France, is documented in St. Ours, Quebec, in 1669, with the secondary surname LaLiberté, which is often translated Liberty; Colin is often Americanized as Collins.

    Colin

  • COLLIN
  • Male

    English

    COLLIN

    Variant spelling of English Colin, COLLIN means "whelp; young pup."

    COLLIN

  • CARLIN
  • Female

    English

    CARLIN

    Irish Gaelic unisex name CARLIN means "little champion."

    CARLIN

  • Cailin
  • Girl/Female

    Irish Gaelic

    Cailin

    Girl.

    Cailin

  • Caylin
  • Girl/Female

    Gaelic

    Caylin

    Girl; lass.

    Caylin

  • Conlin
  • Boy/Male

    Gaelic Irish

    Conlin

    Hero.

    Conlin

  • Collin
  • Boy/Male

    American, Australian, British, Celtic, Christian, Dutch, English, French, Gaelic, German, Greek, Irish, Portuguese

    Collin

    Creative; Victory of the People; Form of Colin; Victor; Abbreviation of Nicholas; Young Creature; People's Victory; Dove; One who had Travelled to Rome; Young Pup

    Collin

  • CAYLIN
  • Female

    English

    CAYLIN

    Variant spelling of English Kaylin, CAYLIN means "girl."

    CAYLIN

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Online names & meanings

  • Dnyaneshwari | த்ந்யநேஷ்வாரீ 
  • Girl/Female

    Tamil

    Dnyaneshwari | த்ந்யநேஷ்வாரீ 

    Bhagwad Geeta

  • Meason
  • Surname or Lastname

    English

    Meason

    English : perhaps a variant of Meacham.

  • Savera
  • Boy/Male

    Hindu, Indian

    Savera

    Morning

  • Shafee | شفیع
  • Boy/Male

    Muslim

    Shafee | شفیع

    Giving shaft, Honest, Truthful, Healer

  • Vibhav
  • Boy/Male

    Hindu, Indian, Kannada, Marathi, Sanskrit, Telugu

    Vibhav

    Friend; Soft Spoken

  • Maherbani
  • Girl/Female

    Indian, Punjabi, Sikh

    Maherbani

    Word of the Headman

  • Cynddelw
  • Boy/Male

    Welsh

    Cynddelw

    Chief statue.

  • Sunhari
  • Girl/Female

    Indian

    Sunhari

    Golden

  • JACQUES
  • Male

    French

    JACQUES

    French diminutive form of Latin Jacobus, JACQUES means "supplanter."

  • Mispar
  • Girl/Female

    Biblical

    Mispar

    Numbering, showing, increase of tribute.

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Other words and meanings similar to

CYCLIN B1

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CYCLIN B1

  • Cyclonic
  • a.

    Pertaining to a cyclone.

  • Circular
  • a.

    Adhering to a fixed circle of legends; cyclic; hence, mean; inferior. See Cyclic poets, under Cyclic.

  • Indiction
  • n.

    A cycle of fifteen years.

  • Cycle
  • v. i.

    To pass through a cycle of changes; to recur in cycles.

  • Lollard
  • n.

    One of the followers of Wyclif in England.

  • Circler
  • n.

    A mean or inferior poet, perhaps from his habit of wandering around as a stroller; an itinerant poet. Also, a name given to the cyclic poets. See under Cyclic, a.

  • Wheelman
  • n.

    One who rides a bicycle or tricycle; a cycler, or cyclist.

  • Wheeling
  • n.

    The act or practice of using a cycle; cycling.

  • Cyclic
  • a.

    Alt. of Cyclical

  • Potestate
  • n.

    A chief ruler; a potentate. [Obs.] Wyclif.

  • Cycling
  • p. pr. & vb. n.

    of Cycle

  • Cyclist
  • n.

    A cycler.

  • Cycle
  • n.

    An interval of time in which a certain succession of events or phenomena is completed, and then returns again and again, uniformly and continually in the same order; a periodical space of time marked by the recurrence of something peculiar; as, the cycle of the seasons, or of the year.

  • Cycle
  • v. i.

    To ride a bicycle, tricycle, or other form of cycle.

  • Cycloidian
  • a. & n.

    Same as 2d and 3d Cycloid.

  • Cycle
  • n.

    One entire round in a circle or a spire; as, a cycle or set of leaves.

  • Cyclical
  • a.

    Of or pertaining to a cycle or circle; moving in cycles; as, cyclical time.

  • Cycling
  • n.

    The act, art, or practice, of riding a cycle, esp. a bicycle or tricycle.

  • Cycled
  • imp. & p. p.

    of Cycle