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Breakdown product of creatine phosphate
Creatinine (/kriˈætɪnɪn, -ˌniːn/; from Ancient Greek κρέας (kréas) 'flesh') is a breakdown product of creatine phosphate from muscle and protein metabolism
Creatinine
Medical laboratory value
urea-to-creatinine ratio (UCR), known in the United States as BUN-to-creatinine ratio, is the ratio of the blood levels of urea (BUN) (mmol/L) and creatinine
Urea-to-creatinine_ratio
Renal function test
through the kidney. The creatinine clearance rate (CCr or CrCl) is the volume of blood plasma that is cleared of creatinine per unit time and is a useful
Glomerular_filtration_rate
Ratio of protein excreted in urine
Urine protein/creatinine ratio is a widely used initial method to estimate daily protein excretion in urine. Since the diagnosis and management of proteinuric
Urine protein/creatinine ratio
Urine_protein/creatinine_ratio
Medical condition
albumin in the sample against its concentration of creatinine is helpful. This is termed the albumin/creatinine ratio (ACR) and microalbuminuria is defined as
Microalbuminuria
Disease where the kidneys fail to adequately filter waste products from the blood
combination of factors such as decreased urine production or increased serum creatinine. Diagnosis of chronic failure is based on a glomerular filtration rate
Kidney_failure
Presence of an excess of serum proteins in the urine
in the urine may be compared to the creatinine level in a spot urine sample. This is termed the protein/creatinine ratio. The 2005 UK Chronic Kidney Disease
Proteinuria
Colorimetric method used in clinical chemistry
reaction is a colorimetric method used in clinical chemistry to determine creatinine levels in blood and urine. In 1886, Max Jaffe (1841–1911) wrote about
Jaffe_reaction
In enzymology, a creatinine deaminase (EC 3.5.4.21) is an enzyme that catalyzes the chemical reaction creatinine + H2O ⇌ {\displaystyle \rightleftharpoons
Creatinine_deaminase
Protein family
catalyses the hydrolysis of creatinine to creatine, which can then be metabolised to urea and sarcosine by creatinase. creatinine + H2O ⇌ {\displaystyle \rightleftharpoons
Creatininase
Blood test
called urea and electrolytes (U&E or "U and Es"), or urea, electrolytes, creatinine (UEC or EUC or CUE), and are often referred to as 'kidney function tests'
Basic_metabolic_panel
Chemical compound
κρέας (kreas). In 1928, creatine was shown to exist in equilibrium with creatinine. Studies in the 1920s showed that consumption of large amounts of creatine
Creatine
Sudden decrease in kidney function that develops within seven days
function that develops within seven days, as shown by an increase in serum creatinine or a decrease in urine output, or both. Causes of AKI are classified as
Acute_kidney_injury
Buildup of metabolic waste due to kidney dysfunction
protein metabolic waste compounds, like urea, uric acid, ammonia, and creatinine. Protein toxicity has many causes, including urea cycle disorders, genetic
Protein_toxicity
Excess urea in the blood due to kidney dysfunction
blood of amino acid and protein metabolism end products, such as urea and creatinine, which would normally be excreted in the urine. Uremic syndrome can be
Uremia
Excess of nitrogen-rich compounds in the blood
abnormally high levels of nitrogen-containing compounds (such as urea, creatinine, and other nitrogen-rich compounds) in the blood. It is largely related
Azotemia
Blood test
detect kidney problems. It is not considered as reliable as creatinine or BUN-to-creatinine ratio blood studies. BUN is an indication of kidney health
Blood_urea_nitrogen
Ways of assessing the function of the kidneys
Bowman's capsule per unit time. Creatinine clearance (CCr) is the volume of blood plasma that is cleared of creatinine per unit time and is a useful measure
Assessment_of_kidney_function
Breed of cat
concentration of creatinine and symmetric dimethylarginine, but most Birman cats have higher concentrations of creatinine than SDMA. Creatinine is a creatine
Birman
Medical therapy for kidney failure
reached when the glomerular filtration rate is less than 15% of the normal, creatinine clearance is less than 10 mL per minute, and uremia is present. Dialysis
Kidney_dialysis
Abnormal presence of albumin in the urine
urine (often measured as urine albumin-to-creatinine ratio of >30 milligrams of albumin per 1 gram of creatinine per day). It is a type of proteinuria, and
Albuminuria
Laboratory analysis performed on a blood sample
potassium, chloride, bicarbonate, blood urea nitrogen (BUN), magnesium, creatinine, glucose, and sometimes calcium. Tests that focus on cholesterol levels
Blood_test
Abnormal kidney structure or gradual loss of kidney function
derived from the serum creatinine and is proportional to 1/creatinine, i.e., it is a reciprocal relationship; the higher the creatinine, the lower the GFR
Chronic_kidney_disease
Class of enzymes
is often listed in medical literature under incorrect name "creatinine kinase". Creatinine is not a substrate or a product of the enzyme. Reference ranges
Creatine_kinase
Percentage of kidney-filtered sodium excreted in urine
plasma × ( [ creatinine ] urinary × UFR [ creatinine ] plasma ) = 100 × [ Na ] urinary × [ creatinine ] plasma [ Na ] plasma × [ creatinine ] urinary {\displaystyle
Fractional excretion of sodium
Fractional_excretion_of_sodium
Antibiotic
(hyperkalemia). Can compete with creatinine for secretion into the renal tubule. This can cause an artificial rise in the serum creatinine. Use in EHEC infections
Trimethoprim
Liquid by-product of animal metabolism
excess water and metabolic by-products including urea, uric acid, and creatinine. In mammals, urine travels from the kidneys via the ureters to the bladder
Urine
Endocrine disease of horses
is currently not recommended for PPID testing. Although corticoid-to-creatinine ratios are generally higher in horses with PPID, numerous false positives
Pituitary pars intermedia dysfunction
Pituitary_pars_intermedia_dysfunction
Medical study concerned with the kidneys
The serum creatinine concentration is the most important blood test as it is used to estimate the function of the kidney, called the creatinine clearance
Nephrology
clearance of inulin. Creatinine is sometimes used instead of inulin as the reference substance; for example, the calcium-creatinine clearance ratio is used
Renal_clearance_ratio
Natural plant polysaccharides
maintaining a reasonably constant level in the plasma. In the United States, creatinine clearance is more widely used to estimate GFR. A 2017 systematic review
Inulin
Incurable progressive feline disease
stages based on the creatinine concentration in the blood plasma, which are further subdivided according to the protein-creatinine quotient in the urine
Chronic kidney disease in cats
Chronic_kidney_disease_in_cats
Study of the physiology of the kidney
Substances mainly secreted into renal tubule are; H+, K+, NH3, urea, creatinine, histamine and drugs like penicillin. Tubular secretion occurs at Proximal
Renal_physiology
Protein used as a biomarker of kidney function
complicated, costly, time-consuming and have potential side-effects. Creatinine is the most widely used biomarker of kidney function. It is inaccurate
Cystatin_C
Medication
subunit alpha agonist. The most common adverse reactions include increased creatinine, dysuria, hematuria, urinary frequency, micturition urgency, urinary tract
Nogapendekin_alfa_inbakicept
Chemical compound
been measured in a range of 0–68 micromoles per millimole (μmol/mmol) of creatinine. In the breast milk of healthy lactating women, HMB and L-leucine have
Β-Hydroxy β-methylbutyric acid
Β-Hydroxy_β-methylbutyric_acid
Smallest type of blood vessel
water, oxygen, carbon dioxide, urea, glucose, uric acid, lactic acid and creatinine. Lymph capillaries connect with larger lymph vessels to drain lymphatic
Capillary
Initial known conditions used for comparison with later data
patient with kidney failure (whose creatinine is usually 3.0 mg/dL) suddenly has a creatinine of 5.0 mg/dL, then his creatinine is out of his normal. For that
Baseline_(science)
Chemical compound
people with creatinine clearance rates equal to or less than 30 mL/minute. A half-life of 22–50 hours has been reported for people with creatinine clearances
Sulfamethoxazole
Chemical compound
day through creatine phosphate. Phosphocreatine can be broken down into creatinine, which is then excreted in the urine. A 70 kg man contains around 120
Phosphocreatine
Blood test assessing vital organ health
interfere with this test. Serum glucose Calcium Blood urea nitrogen (BUN) Creatinine Electrolyte levels and the balance among them are tightly regulated by
Comprehensive_metabolic_panel
Endocrine disorder in cats
non-diabetes related hyperglycaemia. In roughly 10% of hyperthyroid cats serum creatinine levels are increased to the point of azotaemia. In 10-20% of cats increased
Feline_hyperthyroidism
Method of determining chemical concentration
→ colored complex Copper + bathocuproin disulfonate → colored complex Creatinine + picrate → colored complex Iron + bathophenanthroline disulfonate → colored
Colorimetric_analysis
Array of tests performed on urine
associated with glomerular hematuria. Proteinuria and elevated blood creatinine alongside hematuria suggests kidney dysfunction. In people at risk, persistent
Urinalysis
Protein-coding gene in the species Homo sapiens
mortality. Kidney health is most frequently measured by serum creatinine. Serum creatinine is a marker of kidney function, whereas NGAL is a marker of kidney
Lipocalin-2
Change in kidney function during illness
medication through the kidneys. In many cases, it is observed as a measured creatinine clearance above that which is expected given the patient's age, sex, and
Augmented_renal_clearance
Pharmacokinetic measurement
one another. If applied to creatinine (i.e. creatinine clearance), it follows from the equation that if the serum creatinine doubles the clearance halves
Clearance_(pharmacology)
ACE inhibitor medication
unilateral significant renal artery stenosis (RAS). An early rise in serum creatinine above baseline is expected after initiation of therapy with Ramipril,
Ramipril
Amino acid
3-Phosphoglyceric acid glycine→creatine: Glycocyamine Phosphocreatine Creatinine G→glutamate→ α-ketoglutarate histidine→ Urocanic acid Imidazole propionate
Lysine
Medical test of urine
and microscopic examination Urine creatinine, creatinine clearance — used to assess kidney function Albumin/creatinine ratio — used to diagnose microalbuminuria
Urine_test
Inflammation of the kidneys
their kidney function through measurements of BUN, creatinine, urinalysis, urine protein/creatinine ratio, and by trending their estimated glomerular filtration
Lupus_nephritis
called a basic metabolic panel (blood urea nitrogen, carbon dioxide, creatinine, glucose, serum chloride, serum potassium, serum sodium) CHEM-20 a group
List of medical abbreviations: C
List_of_medical_abbreviations:_C
Chemical compound
3-Phosphoglyceric acid glycine→creatine: Glycocyamine Phosphocreatine Creatinine G→glutamate→ α-ketoglutarate histidine→ Urocanic acid Imidazole propionate
Glutamate-5-semialdehyde
German biochemist
various compounds and substances, such as cholesterol (Salkowski's test), creatinine, glucose, carbon monoxide, and indole. In 1892 (with Jastrowitz) he was
Ernst_Leopold_Salkowski
Proteinogenic amino acid
3-Phosphoglyceric acid glycine→creatine: Glycocyamine Phosphocreatine Creatinine G→glutamate→ α-ketoglutarate histidine→ Urocanic acid Imidazole propionate
Cysteine
Chemical compound
3-Phosphoglyceric acid glycine→creatine: Glycocyamine Phosphocreatine Creatinine G→glutamate→ α-ketoglutarate histidine→ Urocanic acid Imidazole propionate
Cysteine_sulfinic_acid
High blood pressure medication
2016 review. ACE inhibitor can result in an initial increase of serum creatinine, but mostly returns to baseline in a few weeks in majority of patients
Perindopril
Type of kidney disorder
compared to that of small molecules (less than 5 kDa) such as water and creatinine. The syndrome is associated with premature death. SPS has been identified
Shrunken_pore_syndrome
Microscopic structural and functional unit of the kidney
phosphate, uric acid, and bicarbonate. Substances secreted include urea, creatinine, potassium, hydrogen, and uric acid. Some of the hormones which signal
Nephron
Medical condition
third CCD. Initially diagnosis is typically established by creatine, creatinine, and guanidinoacetate measurement in the plasma, urine, and/or cerebrospinal
Cerebral_creatine_deficiency
Simplest of the alpha-keto acids
3-Phosphoglyceric acid glycine→creatine: Glycocyamine Phosphocreatine Creatinine G→glutamate→ α-ketoglutarate histidine→ Urocanic acid Imidazole propionate
Pyruvic_acid
Medical condition
degree of pericarditis does not correlate with the degree of serum BUN or creatinine elevation. The pathogenesis is poorly understood. Uremic pericarditis
Uremic_pericarditis
Medical condition resulting from overconsumption of bromine (Br)
serum chloride level, electrolytes, glucose, blood urea nitrogen and creatinine, as well as symptoms such as psychosis. Bromine is also radiopaque, so
Bromism
Failure of the heart to provide sufficient blood flow
strongest risk factor for heart failure. Diabetic women with depressed creatinine clearance or elevated BMI were at the highest risk of heart failure. While
Heart_failure
Viral pulmonary disease of humans
include thrombocytopenia, leukocytosis, hemoconcentration, elevated serum creatinine levels, hematuria, and proteinuria. Hantavirus-specific IgM and IgG antibodies
Hantavirus_pulmonary_syndrome
Medical condition
high sensitivity amino-terminal B-type natriuretic peptide, creatinine kinase, and creatinine kinase myocardial band, which indicate myocardial damage,
Viral_cardiomyopathy
Canine dietary toxicity
ingestion. A blood test may reveal increases in blood urea nitrogen (BUN), creatinine, phosphorus, and calcium. Emesis (induction of vomiting) is the generally
Grape_toxicity_in_dogs
Chemical compound
concentration in urine, creatinine-corrected. Urine concentration is a proxy variable - the measurement is of unmetabolised MOCA - and creatinine-correction affects
4,4'-Methylenebis(2-chloroaniline)
4,4'-Methylenebis(2-chloroaniline)
Accumulation of collagen in the skin and internal organs
elevated serum creatinine level is not a contraindication for ACE inhibitors in this population, and slight elevations in creatinine are common during
Systemic_scleroderma
Medical condition
failure. Patients may present with hyponatremia, hypokalemia, and elevated creatinine. The treatment is supportive until the villous adenoma can be resected
McKittrick–Wheelock_syndrome
Antihypertensive medication
other antihypertensive drugs. Severe depression, severe kidney failure (creatinine clearance <15 ml/min), as a precaution in the absence of currently available
Rilmenidine
Chemical compound
decreased neutrophils, increased alanine aminotransferase (ALT), increased creatinine, increased alkaline phosphatase, fatigue, constipation, musculoskeletal
Pralsetinib
Loop diuretic medication
recommended that serum electrolytes (especially potassium), serum CO2, creatinine, BUN levels, and liver and kidney functioning be monitored in patients
Furosemide
Chemical compound
3-Phosphoglyceric acid glycine→creatine: Glycocyamine Phosphocreatine Creatinine G→glutamate→ α-ketoglutarate histidine→ Urocanic acid Imidazole propionate
L-Arginine_L-pyroglutamate
Endogenous GABA precursor
3-Phosphoglyceric acid glycine→creatine: Glycocyamine Phosphocreatine Creatinine G→glutamate→ α-ketoglutarate histidine→ Urocanic acid Imidazole propionate
N-Acetyl-γ-aminobutyric_acid
Endogenous GABA precursor
3-Phosphoglyceric acid glycine→creatine: Glycocyamine Phosphocreatine Creatinine G→glutamate→ α-ketoglutarate histidine→ Urocanic acid Imidazole propionate
N-Acetylputrescine
Chemotherapy and immunosuppressant medication
complete blood count, liver function tests, and creatinine are recommended. Measurements of creatinine are recommended at least every two months. Folic
Methotrexate
Qualitative chemical test, primarily used for detecting cholesterol
different kinds of molecules (besides cholesterol and other sterols also for creatinine, carbon monoxide, glucose and indoles). A solution that has tested positive
Salkowski's_test
3-Phosphoglyceric acid glycine→creatine: Glycocyamine Phosphocreatine Creatinine G→glutamate→ α-ketoglutarate histidine→ Urocanic acid Imidazole propionate
Cysteine_metabolism
Angiotensin II receptor antagonist
bilateral renal artery stenosis have been reported to have increases in serum creatinine or blood urea nitrogen. There has been no long-term use of olmesartan
Olmesartan
Warm-blooded animals with wings and feathers
nitrogenous wastes as ammonia. They also excrete creatine, rather than creatinine like mammals. This material, as well as the output of the intestines,
Bird
Process used to reduce bacterial and algal residue in water
ineffective with the organic chloramines present in all pool water e.g. with creatinine, an organic component in human sweat. Indeed, superchlorination produces
Shock_chlorination
Pharmaceutical drug
levels), surgical wound complication, weight increase, increased serum creatinine (a marker of kidney problems), hypophosphataemia (low blood phosphate
Basiliximab
Medical condition
pulse oximetry, testing serum electrolyte, blood urea nitrogen (BUN), and creatinine levels, measuring arterial blood gases, chest radiography, electrocardiogram
Chlorine_gas_poisoning
Medical condition
including histochemical staining of renal biopsy specimens, the measure of creatinine level, GFR level, and urine output, urine microscopy, CT scanning, and
Phosphate_nephropathy
Physical substance of the human organism
through their respective nephrons, removing waste products like urea, creatinine and maintaining the proper balance of electrolytes and turning the waste
Human_body
Percentages of fat, bone, water and muscle in human bodies
circumference (MAMC), and creatinine height ratio (CHI). Creatinine height ratio is calculated as 24-hour urine creatinine multiplied by 100 over the
Body_composition
Chemical compound
warns against a mean rise in serum creatinine of 0.11 mg/dL due to inhibition of tubular secretion of creatinine and does not affect GFR. In 2019 there
Dolutegravir
Extreme manifestation of hypothyroidism
features in myxedema coma: Anemia Elevated creatine kinase (CPK) Elevated creatinine Elevated transaminases Hypercapnia Hypercholesterolemia (elevated LDL)
Myxedema_coma
Anti-inflammatory drug
levels) Hypernatremia (high sodium levels) Hypertension Elevations of serum creatinine and more serious renal damage such as acute kidney failure, chronic nephritis
Indometacin
Disease of the kidney
hypertension, smoking, hyperlipidemia, older age, familial disease and elevated creatinine concentrations are markers of a poor outcome. Frank hematuria has shown
IgA_nephropathy
Diuretics that act along the loop of Henle in the kidneys
can only replace thiazide-type diuretics if there is renal impairment (Creatinine of more than 1.5 mg/dL or estimated glomerular filtration rate (eGFR)
Loop_diuretic
Medical condition
exposure indices for blood and urine cadmium levels are 5 μg/L and 5 μg/g creatinine, respectively, in random specimens. Persons who have sustained kidney
Cadmium_poisoning
Chemical compound
identify alcohol components in esters and in the fluorometric analysis of creatinine. 3,5-dinitrobenzoic acid is obtained from benzoic acid by the nitration
3,5-Dinitrobenzoic_acid
Life-threatening response to infection
coagulation Kidney dysfunction serum creatinine ≥ 2 times the upper limit of normal for age or 2-fold increase in baseline creatinine in people with chronic kidney
Sepsis
Medical condition
ovary, ascites, hematocrit > 45%, WBC > 15,000, oliguria, creatinine 1.0–1.5 mg/dl, creatinine clearance > 50 ml/min, liver dysfunction, and anasarca. Critical
Ovarian hyperstimulation syndrome
Ovarian_hyperstimulation_syndrome
Chemical compound found in all domains of life with largely unexplored effects
3-Phosphoglyceric acid glycine→creatine: Glycocyamine Phosphocreatine Creatinine G→glutamate→ α-ketoglutarate histidine→ Urocanic acid Imidazole propionate
S-Adenosyl_methionine
Organic compound
3-Phosphoglyceric acid glycine→creatine: Glycocyamine Phosphocreatine Creatinine G→glutamate→ α-ketoglutarate histidine→ Urocanic acid Imidazole propionate
Fumaric_acid
Antibiotic medication
> 90% was available, and kidney toxicity defined by an increase in serum creatinine of at least 0.5 mg/dL occurred in only about 5% of patients. But dosing
Vancomycin
Chemical compound
techniques. A biological exposure index of 200 mg 2-butoxyacetic acid per g creatinine has been established in an end-of-shift urine specimen for U.S. employees
2-Butoxyethanol
CREATININE
CREATININE
CREATININE
CREATININE
Boy/Male
Arabic, Muslim
Responsible; Sponsor; Surety
Girl/Female
British, English
Form of Dorothy; A Gift of God
Female
English
Modern English form of French Cerise, SHERISSE means "cherry."Â
Girl/Female
Bengali, Indian
Kind; Find
Boy/Male
Tamil
Jahangeer | ஜஹாஂகீர
World conqueror, A moghul emperor, Akbars son
Girl/Female
Welsh
meaning lovable.
Girl/Female
Muslim
Fourth.
Girl/Female
Arabic
The Moon
Male
Scottish
 Short form of Scottish Gaelic Alestair, ALEC means "defender of mankind." Compare with other forms of Alec.
Boy/Male
Hindu
CREATININE
CREATININE
CREATININE
CREATININE
CREATININE