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Glycoprotein layer surrounding the plasma membrane of mammalian oocytes
The zona pellucida (Latin meaning "transparent zone") is the specialized area surrounding mammalian oocytes (eggs). It is also known as an egg coat. The
Zona_pellucida
Protein-coding gene in the species Homo sapiens
Zona pellucida sperm-binding protein 1 is a protein that in humans is encoded by the gene ZP1. The ZP1 protein, together with the related proteins ZP2
ZP1
Union of a human egg and sperm
enzymes which allow it to burrow through the outer shell called the zona pellucida of the egg. The sperm plasma then fuses with the egg's plasma membrane
Human_fertilization
zona pellucida (PZP) is the zona pellucida extracted from the ovaries of pigs which is used as a source of antigens for immunocontraception. The zona
Porcine_zona_pellucida
Using an animal's anti-disease protections against its reproductive system
trials typically check for signs of autoimmune disease. One concern with zona pellucida vaccination, in particular, is that in certain cases it appears to be
Immunocontraception
Development and formation of the human embryo
blastocyst causes it to hatch through the zona pellucida, which then disintegrates. This process is called zona hatching and it takes place on the sixth
Human_embryonic_development
Protein domain
The zona pellucida-like domain (ZP domain / ZP-like domain / ZP module) is a large protein region of about 260 amino acids. It has been recognised in a
Zona_pellucida-like_domain
Failure of an embryo to implant
affected by maternal and paternal genetic abnormalities as well as zona pellucida dysfunction and poor embryo transfer technique. The quality of the sperm
Repeated_implantation_failure
Method of testing human sperm viability
egg is measured. The hamster eggs have had the zona pellucida, the outer membrane, removed—hence, zona-free. Having all eggs penetrated by multiple sperm
Hamster_zona-free_ovum_test
Biological process that prevents polyspermy
the cortical reaction is the zona pellucida. This modification of the zona pellucida is known as the zona reaction or zona hardening. Although highly conserved
Cortical_reaction
Union of opposite-sex gametes in sexual reproduction to form a zygote
independently binds to the zona. After the acrosome reaction, the sperm is believed to remain bound to the zona pellucida through exposed ZP2 receptors
Fertilisation
Cellular mantle around egg cell
of the cells of the cumulus oophorus and is directly adjacent to the zona pellucida, the inner protective glycoprotein layer of the ovum. Cumulus oophorus
Corona_radiata_(embryology)
Male reproductive cell
make up the zona pellucida, then binds to a partner molecule on the sperm. Enzymes on the inner acrosomal membrane digest the zona pellucida. After the
Sperm
First stage of pregnancy
Assisted zona hatching may take place in assisted reproduction, where the zona pellucida may be artificially pierced to facilitate hatching. Following zona hatching
Implantation_(embryology)
Protein-coding gene in the species Homo sapiens
Zona pellucida sperm-binding protein 3, also known as zona pellucida glycoprotein 3 (Zp-3) or the sperm receptor, is a ZP module-containing protein that
ZP3
Assisted reproductive technology procedure
zona pellucida (mechanically, chemically or by laser) to facilitate hatching. Zona hatching is where the blastocyst gets rid of the surrounding zona pellucida
Assisted_zona_hatching
External genitalia of the female mammal
Thecae Externa Interna Follicular antrum Follicular fluid Corona radiata Zona pellucida Membrana granulosa Perivitelline space Other Germinal epithelium Tunica
Vulva
Middle membrane of Ovum
The perivitelline space is the space between the zona pellucida and the cell membrane of an oocyte or fertilized ovum. In the slow block to polyspermy
Perivitelline_space
Protein-coding gene in the species Homo sapiens
Zona pellucida sperm-binding protein 4, ZP-4 or avilesine, named after its discoverer Manuel Avilés Sánchez is a protein that in humans is encoded by the
ZP4
Sperm-meets-egg process
straightforward, penetrating the egg's protective layers, such as the zona pellucida, presents a significant challenge. Therefore, sperm cells go through
Acrosome_reaction
extracellular matrix, particularly the zona pellucida. This alteration of the zona pellucida components is known as the zona reaction. The cortical reaction
Cortical_granule
Protein-coding gene in the species Homo sapiens
Zona pellucida sperm-binding protein 2 is a protein that in humans is encoded by the ZP2 gene. The zona pellucida is an extracellular matrix that surrounds
ZP2
Mammalian protein found in Homo sapiens
consequence of the acrosome reaction. It aids in the penetration of the Zona Pellucida. Acrosin is a typical serine proteinase with trypsin-like specificity
Acrosin
Female reproductive organ that produces egg cells
membrana granulosa (and the granulosa cells inside it), corona radiata, zona pellucida, and primary oocyte. Theca of follicle, antrum and liquor folliculi
Ovary
Part of the vulva that covers and protects the glans of the clitoris
Thecae Externa Interna Follicular antrum Follicular fluid Corona radiata Zona pellucida Membrana granulosa Perivitelline space Other Germinal epithelium Tunica
Clitoral_hood
Genetic profiling of embryos prior to implantation
embryo and/or blastomere. Currently, zona drilling using a laser is the predominant method of opening the zona pellucida. Using a laser is an easier technique
Preimplantation genetic diagnosis
Preimplantation_genetic_diagnosis
Reproductive system of female humans
Thecae Externa Interna Follicular antrum Follicular fluid Corona radiata Zona pellucida Membrana granulosa Perivitelline space Other Germinal epithelium Tunica
Female_reproductive_system
Immature ovum or egg cell
Thecae Externa Interna Follicular antrum Follicular fluid Corona radiata Zona pellucida Membrana granulosa Perivitelline space Other Germinal epithelium Tunica
Oocyte
Act of lengthening the labia minora
Thecae Externa Interna Follicular antrum Follicular fluid Corona radiata Zona pellucida Membrana granulosa Perivitelline space Other Germinal epithelium Tunica
Labia_stretching
Structure formed around day 5 of mammalian embryonic development
the blastocyst into the endometrium requires that it hatches from the zona pellucida, the egg coat that prevents adherence to the fallopian tube as the pre-embryo
Blastocyst
primordial follicles, each of consists of a small oocyte (with no zona pellucida) and a single layer of flattened pre-granulosa cells, can first be observed
Canine_follicle_development
Method of determining sex
other mammals, are covered with a thick translucent layer called the zona pellucida, which the sperm must penetrate to fertilize the egg. Once viewed simply
XY_sex-determination_system
System describing embryonic development
before hatching from the zona pellucida. During this process, the blastocyst breaks through and escapes from the zona pellucida. This process must occur
Carnegie_stages
Penultimate step in the activation of mammalian spermatozoa
through the outer layers of an oocyte, namely the cumulus ooporus and the zona pellucida. Capacitation results in hyperactivation of sperm motility, with the
Capacitation
Division of cells in the early embryo
tightly adhered epithelial cells. They are still enclosed within the zona pellucida. The morula is now watertight, to contain the fluid that the cells will
Cleavage_(embryo)
Mammalian protein found in Homo sapiens
stimulates binding of the spermatozoa to the zona pellucida. First, cumulus cells reduce the spermatozoa-zona binding inhibitory activity of follicular fluid
Glycodelin
Prior to implantation, the embryo remains in a protein shell, the zona pellucida, and undergoes a series of rapid mitotic cell divisions called cleavage
Development_of_the_human_body
Human body part
Thecae Externa Interna Follicular antrum Follicular fluid Corona radiata Zona pellucida Membrana granulosa Perivitelline space Other Germinal epithelium Tunica
Perineal_raphe
Mammalian protein found in Homo sapiens
Uromodulin (UMOD),Tamm–Horsfall protein (THP), is a zona pellucida-like domain-containing glycoprotein that in humans is encoded by the UMOD gene. Uromodulin
Uromodulin
Topics referred to by the same term
subthalamus below the thalamus Zona pellucida, a glycoprotein membrane surrounding the plasma membrane of an oocyte Zona Rosa, Mexico City This disambiguation
Zona_(disambiguation)
Structure surrounding the surface of the plasma membrane of an ovum
contributes to prevention of breeding between different species. It is called zona pellucida in mammals. Between the vitelline membrane and the oolemma (ovum cell
Vitelline_membrane
One of two offspring produced by the same pregnancy
fetus, rather than by the embryo splitting while hatching from the zona pellucida (the gelatinous protective coating around the blastocyst). Monozygotic
Twin
protein–protein recognition and cell adhesion, potentially binding zona pellucida ligands or oocyte membrane receptors. Disintegrin domains in ADAM proteins
ADAM20
Diploid eukaryotic cell formed by fertilization between two gametes
approaches the site of implantation. When the blastocyst hatches from the zona pellucida, it can implant in the endometrial lining of the uterus and begin the
Zygote
Enzyme
acid induced cell signaling, and a receptor that is involved in sperm-zona pellucida adhesion. Abnormal expression of this gene in tumors has implicated
SPAM1
Process of maturation of primordial follicles
capsule called the zona pellucida forms around the oocyte, separating it from the surrounding granulosa cells. The zona pellucida, which remains with
Folliculogenesis
Gamete-producing cell
maturity that the primary oocytes secrete proteins to form a coat called zona pellucida and they also produce cortical granules containing enzymes and proteins
Germ_cell
Topics referred to by the same term
ZP may refer to: Zp, the ring of p-adic integers Zona pellucida (or egg coat), a glycoprotein layer around an oocyte Z/pZ, the cyclic group of integers
ZP
Medical condition
chromatin. This makes the sperm completely unable to penetrate the zona pellucida. The sperm in Type 2 globozoospermia has some acrosomal covering surrounded
Globozoospermia
perversity Polysexuality Pompoir POPLINE Population Council Porcine zona pellucida Porn groove Porn Sunday Pornographic film actor Pornography Pornography
Index of human sexuality articles
Index_of_human_sexuality_articles
Medical condition
Thecae Externa Interna Follicular antrum Follicular fluid Corona radiata Zona pellucida Membrana granulosa Perivitelline space Other Germinal epithelium Tunica
Ovarian_remnant_syndrome
Procedure performed prior to IVF
quality in terms of morphological characteristics are the cumulus cells, zona pellucida, polar body, perivitelline space, and cytoplasm; These are the main
Oocyte_selection
Procedure to preserve a woman's eggs (oocytes)
controlled trials are still lacking. During the freezing process, the zona pellucida, or shell of the egg, can be modified, preventing fertilization. Thus
Oocyte_cryopreservation
American Developmental Biologist
His laboratory identified and characterised proteins that make up the zona pellucida (ZP) of mammalian eggs and determined their role in fertilisation. He
Paul_M._Wassarman
Union of an egg and sperm to form a zygote within the female body
and associations, piercings of the oocyte zona pellucida by sperm, and reactions such as the cortical and zona reactions. Sperm capacitation is a process
Internal_fertilization
Period of reproduction
Then, a flat layer cell forms on the exterior of this cavity, and the zona pellucida, the blastocyst's barrier, remains the same size as before. Cells grow
Pregnancy_(mammals)
Measure of male fertility
Hemizona test is a test to evaluate sperm zona-binding capacity. In this test, the two halves of human zona pellucida are incubated with the patient's capacitated
Semen_quality
Protein found in humans
Biological process protein folding single fertilization binding of sperm to zona pellucida protein-containing complex assembly Sources:Amigo / QuickGO Orthologs
Calmegin
Female reproductive system health issue
does not reach the uterus in time, will hatch from the non-adhesive zona pellucida and implant itself inside the fallopian tube, thus causing ectopic pregnancy
Ectopic_pregnancy
Chemical compound
egg cell. For fertilization to occur, human sperm must bind to the zona pellucida (ZP), the translucent matrix covering the human egg composed of four
Sialyl-Lewis_X
In vitro fertilization procedure
thick zona pellucida (covering) around the embryo, have ideal candidates for assisted zona hatching. The procedure involves creating a hole in the zona to
Intracytoplasmic sperm injection
Intracytoplasmic_sperm_injection
Organelle of sperm cells
These enzymes break down the outer membrane of the ovum, called the zona pellucida, allowing the haploid nucleus in the sperm cell to join with the haploid
Acrosome
Human-selected breeding
co-incubation of female and male gametes in simple IVF. A plug of the zona pellucida is removed and a single sperm cell is injected into the ooplasm of the
Horse_breeding
Non-surgical methods of avoiding unattended pregnancy in domestic animals
gonadotropin-releasing hormone (GnRH) and porcine zona pellucida (PZP) are known as GonaCon™ and ZonaStat-H/ZonaStat-D, respectively. Both have been approved
Non-surgical fertility control for dogs and cats
Non-surgical_fertility_control_for_dogs_and_cats
Primary layer of cells in embryonic development
embryoblast. Filled with uterine fluid, the blastocyst breaks out of the zona pellucida and undergoes implantation. The inner cell mass initially has two layers:
Germ_layer
Byproduct of oogenesis
stages of segmentation of a mammalian embryo. Semidiagrammatic. z.p. Zona pellucida. p.gl. Polar bodies. a. Two-cell stage. b. Four-cell stage. c. Eight-cell
Polar_body
Genus of Old World monkeys
birds from macaque predation, live trapping, and the vaccine porcine zona pellucida (PZP), which causes infertility in females. In January 2018, scientists
Macaque
the fusing of spermatozoa to the zona pellucida (ZP). Normally in fertilisation, spermatozoa fuse with the zona pellucida surrounding the mature oocyte;
Reproductive_immunology
Species of Old World monkey
has become a popular tourist attraction. The immunovaccine porcine zona pellucida (PZP), which causes infertility in females, is currently being tested
Macaca_fascicularis
Protein-coding gene in the species Homo sapiens
pericentriolar material myelin sheath microtubule organizing center zona pellucida receptor complex heterochromatin acrosomal vesicle chaperonin-containing
T-complex_1
Structures that maintain the position of the vagina within the pelvic cavity
Thecae Externa Interna Follicular antrum Follicular fluid Corona radiata Zona pellucida Membrana granulosa Perivitelline space Other Germinal epithelium Tunica
Vaginal_support_structures
Protein-coding gene in humans
component cell body centrosome myelin sheath microtubule organizing center zona pellucida receptor complex nucleolus chaperonin-containing T-complex microtubule
T-complex protein 1 subunit epsilon
T-complex_protein_1_subunit_epsilon
Expanded region of the vaginal canal at the internal end of the vagina
Thecae Externa Interna Follicular antrum Follicular fluid Corona radiata Zona pellucida Membrana granulosa Perivitelline space Other Germinal epithelium Tunica
Vaginal_vault
Protein-coding gene in humans
binding Cellular component cell body myelin sheath plasma membrane zona pellucida receptor complex chaperonin-containing T-complex microtubule cytoskeleton
CCT3
Protein-coding gene in humans
centrosome cell projection cilium nucleoplasm microtubule organizing center zona pellucida receptor complex intermediate filament cytoskeleton microtubule extracellular
CCT8
Process in which an embryo and later fetus develops during gestation
embryo, as it is confined within a glycoprotein shell, known as the zona pellucida. Instead, each division produces successively smaller cells. The blastocyst
Prenatal_development
Process by which animal embryos form and develop
– is made of glycoproteins and is known as the vitelline membrane (zona pellucida in mammals). Different taxa show different cellular and acellular envelopes
Animal_embryonic_development
Medical condition
Thecae Externa Interna Follicular antrum Follicular fluid Corona radiata Zona pellucida Membrana granulosa Perivitelline space Other Germinal epithelium Tunica
Vaginitis_emphysematosa
Thecae Externa Interna Follicular antrum Follicular fluid Corona radiata Zona pellucida Membrana granulosa Perivitelline space Other Germinal epithelium Tunica
Corpus_hemorrhagicum
Type of sperm cell motility
(flagellum). This type of motility may aid in sperm penetration of the zona pellucida, which encloses the ovum. Hyperactivation could then be followed by
Hyperactivation
Thecae Externa Interna Follicular antrum Follicular fluid Corona radiata Zona pellucida Membrana granulosa Perivitelline space Other Germinal epithelium Tunica
List_of_vaginal_tumors
Protein found in humans
of sperm through the uterus to the oviduct as well as binding to the zona pellucida. Inactivation of ADAM3 is a cause of male infertility. Numerous studies
ADAM3
Protein-coding gene in the species Homo sapiens
membrane Biological process flagellated sperm motility penetration of zona pellucida single fertilization Sources:Amigo / QuickGO Orthologs Species Human
Sperm mitochondrial-associated cysteine-rich protein
Sperm_mitochondrial-associated_cysteine-rich_protein
Protein-coding gene in the species Homo sapiens
oligosaccharide catabolic process metabolism lysosome organization penetration of zona pellucida ganglioside catabolic process positive regulation of transcription by
HEXB
Practice of controlling size of animal population
Another type of vaccine that is being used in deer is called porcine zona pellucida (PZP). PZP works by blocking sperm with antibodies on the deer's egg
Population_control
include embryonic stem cells. The embryo hatches from its protein shell (zona pellucida) and performs implantation onto the endometrial lining of the mother's
Timeline of human prenatal development
Timeline_of_human_prenatal_development
Failure to separate properly during cell division
accomplished through zona drilling or laser drilling. Blastomere biopsy is a technique in which blastomeres are removed from the zona pellucida. It is commonly
Nondisjunction
Benign growths of the vaginal epithelium
Thecae Externa Interna Follicular antrum Follicular fluid Corona radiata Zona pellucida Membrana granulosa Perivitelline space Other Germinal epithelium Tunica
Vaginal_cysts
American horse breed
(2009). "Immunocontraceptive Reproductive Control Utilizing Porcine Zona Pellucida (PZP) in Federal Wild Horse Populations" (PDF) (2nd ed.). American Wild
Chincoteague_pony
Diminished or absent ability of a female to achieve conception
hypogonadism TACR3 Tachykinin receptor 3 Normosmic hypogonadotrophic hypogonadism ZP1 zona pellucida glycoprotein 1 Dysfunctional zona pellucida formation
Female_infertility
Protein-coding gene in the species Homo sapiens
renal water homeostasis cGMP-mediated signaling binding of sperm to zona pellucida Sources:Amigo / QuickGO Orthologs Species Human Mouse Entrez 5576 19087
PRKAR2A
Protein-coding gene in the species Homo sapiens
glycoprotein biosynthetic process epithelial cell development penetration of zona pellucida cell adhesion lactose biosynthetic process extracellular matrix organization
B4GALT1
Protein with oligosaccharide modifications
platelet aggregation and adherence to the endothelium. components of the zona pellucida, which surrounds the oocyte, and is important for sperm-egg interaction
Glycoprotein
is affected. Subtle signs of submucous cleft palate may include the zona pellucida (a pale coloring of the midline of the palate, indicative of a submucous
Classification of cleft lip and cleft palate
Classification_of_cleft_lip_and_cleft_palate
Removal of an animal's reproductive organ
Female mammals – Vaccine of antigens (derived from purified porcine zona pellucida) encapsulated in liposomes (cholesterol and lecithin) with an adjuvant
Neutering
Outer portion of the ovary
Thecae Externa Interna Follicular antrum Follicular fluid Corona radiata Zona pellucida Membrana granulosa Perivitelline space Other Germinal epithelium Tunica
Ovarian_cortex
16-32 cells in a ball within a translucent, elastic layer called the zona pellucida. It will then undergo compaction which is a process where the cells
Morphokinetics_IVF
American plastic surgeon
mutations that replaced highly conserved amino acid residues within the zona pellucida (ZP) domain of α-tectorin. Chen, Achih H.; Becker, Adam M. (September
Achih_H._Chen
Egg cell production process
which release glycoproteins and proteoglycans acids that will form the zona pellucida, which accompany the installation. In the preantral secondary follicle
Oogenesis
Fertilization of an egg by more than one sperm
the egg (the zona pellucida), and additional mechanisms that are not well understood modify the egg's plasma membrane. The zona pellucida is modified by
Polyspermy
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